Tumor-stroma interaction - Pasonen-Seppänen group

01.09.2019 -
Tumor microenvironment (TME) has an active contribution to tumor development and cancer progression. This extremely complex system is composed of multiple cell types, such as fibroblasts and infiltrating immune cells, and structural extracellular matrix (ECM), which is mainly composed of hyaluron...

Human Brain Disease Modelling (Lehtonen lab)

Our research focuses on revealing the cellular and molecular mechanisms of neurological diseases, especially Parkinson`s disease (PD). We utilize patient-derived brain cells in novel human-based models, including 3D culture systems and midbrain organoids, to more accurately mimic the diseased bra...

Neurobiology of disease

24.10.2017 -
The main goal of our research is to understand the mechanisms that lead to neurodegenerative diseases and to identify novel therapeutic approaches for them. We are interested in the effects of environmental factors (such as air pollution and viral infections) and lifestyle factors on brain healt...

Jenni Kublbeck

Project Researcher , A.I. Virtanen Institute for Molecular Sciences

Molecular Pathology and Genetics of Cancer

We study the etiology and pathogenesis of malignant diseases with a special emphasis on the histopathologic, molecular pathologic and genetic/genomic factors. Profound collaboration between several research groups at the UEF and Kuopio University Hospital (KUH) as well as with our national and in...