Our research focus lies in the genetic background and molecular mechanisms underpinning neurodegenerative diseases, especially frontotemporal dementia (FTD). To this end, we utilize a variety of in vitro and in vivo model systems and patient-derived cells, clinical samples and data. We are especi...
Research focus: pathogenesis of Alzheimer's research, particularly search for new biomarkers for neurodegenerative diseases.
Biomarkers for neurodegenerative diseases are needed for early diagnosis, follow-up of the progression of the disease and monitoring of therapeutic responses...
Rapid advances in non-invasive neuroimaging methods have revolutionized the possibilities to study changes occurring in living brain across a variety of time-scales ranging from seconds to an entire life span. A large part of these advances can be attributed to the development of dedicated comput...
Clinical Alzheimer Research groups have a wide expertise in clinical and population based cohorts, risk factors, neuropsychology, biomarkers, genetics, brain imaging, and clinical interventions and trials in AD and mild cognitive impairment.
Our major research areas are:
- Prognosis, risk factors and biomarkers of epilepsy
- Rare or Orphan epilepsies
- Genetics of epilepsies
- Methodological development
- Clinical epilepsy trials at Kuopio Epilepsy Center
Our major research areas are:
- Psychiatric manifestations in frontotemporal dementia
- Role and etiology of cognitive decline in psychiatric disorders
- Imaging and biomarkers in diagnostics and predicting the clinical course of frontotemporal lobar degeneration