The Immune System in Skin Cancers

The research project, constituting a part of the North-Savo Skin Cancer Program (NoSCaP), is aimed at enhancing secondary prevention of skin cancers through identification of patients at increased risk for skin cancers.

Professor Ilkka Harvima and Dr Hanna Siiskonen, Department of ...

Latonen Lab - Cancer stress biology

We study the molecular, cellular and tissue mechanisms that contribute to the increased ability of cancer cells to tolerate stress. We focus on the molecular mechanisms behind the different capacities of cancer and neuronal cells to deal with protein and RNA aggregates, and the ability of cancer ...

Redox signaling (Anna-Liisa Levonen group)

Nrf2 is a transcription factor mainly involved in combating cellular stress caused by reactive oxygen and nitrogen species. However, Nrf2 is also involved in cancer and cardiometabolic diseases, making it an essential drug target.

Molecular Pathology and Genetics of Cancer

We study the etiology and pathogenesis of malignant diseases with a special emphasis on the histopathologic, molecular pathologic and genetic/genomic factors. Profound collaboration between several research groups at the UEF and Kuopio University Hospital (KUH) as well as with our national and in...

Tumor-stroma interaction - Pasonen-Seppänen group

01.09.2019 -
Tumor microenvironment (TME) has an active contribution to tumor development and cancer progression. This extremely complex system is composed of multiple cell types, such as fibroblasts and infiltrating immune cells, and structural extracellular matrix (ECM), which is mainly composed of hyaluron...

Quantitative cell biology

01.10.2020 -
In the Quantitative Cell Biology laboratory, we study the biology of cells through the prism of quantitative sciences. We use cutting edge quantitative bio-imaging tools to count biomolecules such as proteins or mRNAs, measure their interactions, clustering or quantify their motion in live cells ...