Genetics of gene regulation in disease

Transcription factors regulate their target genes not only upon specific stimuli, but also through binding to specific DNA sequences. Genetic variation that occurs on those binding sequences may disturb target gene expression. It is also a potential source for the “missing variation” in polygenic...

Molecular Medicine

World leading laboratory in cardiovascular and malignant glioma gene therapy. Main focus of the research is on the development of new gene drugs, translational research and phase I/II human clinical trials.

Nihay Laham Karam

Assistant Professor , A.I. Virtanen Institute for Molecular Sciences

Tiia Turunen

Grant-funded Researcher , A.I. Virtanen Institute for Molecular Sciences

Vascular Biology (Laakkonen)

'From basic science to translational impact.'
The goal of our junior research group is to improve therapeutics and diagnostics of cardiovascular diseases by understanding the biology behind the diseases. The main focus is in studying vascular anomalies and aortic aneurysms. Particularly ...

Clinical Nutrition and Nutrition Therapy

Our research is based on randomized controlled dietary inervention studies examining the effects of nutrients, diet and lifestyle on metabolism and risk of non-communicable diseases. We concentrate on the health effects of the quality of dietary fat, dietary fiber and dietary patterns. Lately, we...

Redox signaling (Anna-Liisa Levonen group)

Nrf2 is a transcription factor mainly involved in combating cellular stress caused by reactive oxygen and nitrogen species. However, Nrf2 is also involved in cancer and cardiometabolic diseases, making it an essential drug target.

Neurobiology of Memory

Our research group investigates neurobiological mechanisms underlying memory impairment in Alzheimer’s disease and searches for new treatment options to halt the disease progression.