Molecular Pathology and Genetics of Cancer

We study the etiology and pathogenesis of malignant diseases with a special emphasis on the histopathologic, molecular pathologic and genetic/genomic factors. Profound collaboration between several research groups at the UEF and Kuopio University Hospital (KUH) as well as with our national and in...

Genetics of gene regulation in disease

Transcription factors regulate their target genes not only upon specific stimuli, but also through binding to specific DNA sequences. Genetic variation that occurs on those binding sequences may disturb target gene expression. It is also a potential source for the “missing variation” in polygenic...

Molecular Genetics of Alzheimer's Disease

Alzheimer’s disease (AD) is the most common neurodegenerative disorder in the world, which affects up to 50% of individuals above the age of 85. Due to the global increase in the aging population, early diagnosis and treatment of AD are becoming increasingly important, not only from a human point...

Single Cell Genomics Core

Single cell genomics technologies are transforming our understanding of biology and disease. This technology can be applied across a breadth of research areas to provide detailed cellular maps of tissues, organoids, and cell-based models.

As a part of the national Biocenter Finlan...

Cancer Center of Eastern Finland - CCEF

Cancer Center of Eastern Finland - CCEF - is an alliance of research groups extending from the fields of basic molecular science to Kuopio University Hospital clinics.

CCEF includes strong research infrastructure, wide-ranging national and foreign networking as well as top level s...