Leaders
Translational genomics and mechanics training programme focuses on
1. basic genomics research of major common diseases
2. molecular research cardiovascular and metabolic diseases and neurosciences
3. translational research aiming at clinical adaptation of research results
European and global health care is faced with a growing burden of major age-associated diseases. New means of diagnosis and treatment are needed to survive the challenges in health care.
With long time established and successful experience in both research and researcher training, the GenomMed programme will provide the ESRs:
* multidisciplinary research skills that will enable pursuit of an academic career and employment to R&D positions outside academia
* increased transferable skills leading to employment in private and health care sectors, enhanced entrepreneurship, and academic careers
* increased innovation potential of individuals leading to creation of new health care products, services, treatments and more efficient health care processes, i.e. increasing the research and innovation output
* abilities to make greater contributions to the society, both helping the knowledge-based society and creating a meaningful life and career
Cooperation
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Mechanisms of cancer and metabolic disease (Levonen Lab) 01.01.2010 -
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Molecular Physiology 01.01.2009 -
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Molecular Medicine 01.01.1995 -
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Biomedical MRI 01.01.1995 -
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Epilepsy Research
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Cardiovascular Genomics (Kaikkonen lab) 01.09.2015 -
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Annakaisa Haapasalo Group (Molecular Neurodegeneration) 01.06.2015 -
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Neuroinflammation research group 01.01.2017 -
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Biomedical Image Analysis 01.11.2016 -
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Molecular Genetics of Alzheimer's Disease - Hiltunen Lab 01.01.2022 -
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Diabetes and Heart Disease Research Unit 01.08.1994 -
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T2D-Data 12.05.2023 -
Keywords
Leaders
Doctoral Researchers
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Simone Adinolfi
Project Researcher -
Mustafa Beter
Postdoctoral ResearcherA.I. Virtanen Institute for Molecular Sciences, Faculty of Health Sciences -
Lenka Dvoráková
Doctoral ResearcherA.I. Virtanen Institute for Molecular Sciences, Faculty of Health Sciences -
Aarthi Ravindran
Early Stage ResearcherA.I. Virtanen Institute for Molecular Sciences, Faculty of Health Sciences -
Flavia Scoyni
Visiting ResearcherA.I. Virtanen Institute for Molecular Sciences, Faculty of Health Sciences -
Juan Valverde Martínez
Visiting ResearcherA.I. Virtanen Institute for Molecular Sciences, Faculty of Health Sciences
Supporting Staff
Publications
20 items-
A Novel Genetic Marker for the C9orf72 Repeat Expansion in the Finnish Population
Rostalski, H; Korhonen, V; Kuulasmaa, T; Solje, E; Krüger, J; Gen, F; Kaivola, K; Eide, PK; Lambert, JC; Julkunen, V; Tienari, PJ; Remes, AM; Leinonen, V; Hiltunen, M; Haapasalo, A. 2021. Journal of Alzheimer's disease. 83: 1325-1332 -
Automated joint skull-stripping and segmentation with Multi-Task U-Net in large mouse brain MRI databases
De Feo, Riccardo; Shatillo, Artem; Sierra, Alejandra; Valverde, Juan Miguel; Gröhn, Olli; Giove, Federico; Tohka, Jussi. 2021. Neuroimage. 229: 117734 -
C9orf72 hexanucleotide repeat expansion leads to altered neuronal and dendritic spine morphology and synaptic dysfunction
Huber, Nadine; Hoffmann, Dorit; Giniatullina, Raisa; Rostalski, Hannah; Leskelä, Stina; Takalo, Mari; Natunen, Teemu; Solje, Eino; Remes, Anne M.; Giniatullin, Rashid; Hiltunen, Mikko; Haapasalo, Annakaisa. 2021. Neurobiology of disease. 2022; 162: 105584 -
Characterization of a functional endothelial super-enhancer that regulates ADAMTS18 and angiogenesis
Mushimiyimana, I; Niskanen. H; Beter, M; Laakkonen, JP; Kaikkonen, MU; Ylä-Herttuala, S; Laham-Karam, N. 2021. Nucleic acids research. 49: 8078-8096 -
Expression of C9orf72 hexanucleotide repeat expansion leads to formation of RNA foci and dipeptide repeat proteins but does not influence autophagy or proteasomal function in neuronal cells
Leskelä, Stina; Huber, Nadine; Hoffmann, Dorit; Rostalski, Hannah; Remes, Anne M; Takalo, Mari; Hiltunen, Mikko; Haapasalo, Annakaisa. 2021. Biochimica et biophysica acta: molecular cell research. 1868: 119021 -
FTLD Patient-Derived Fibroblasts Show Defective Mitochondrial Function and Accumulation of p62
Leskelä, S; Hoffmann, D; Rostalski, H; Huber, N; Wittrahm, R; Hartikainen, P; Korhonen, V; Leinonen, V; Hiltunen, M; Solje, E; Remes, AM; Haapasalo, A. 2021. Molecular neurobiology. 58: 5438-5458 -
Indole-3-Propionic Acid, a Gut-Derived Tryptophan Metabolite, Associates with Hepatic Fibrosis
Sehgal, Ratika Ilha, Mariana Vaittinen, Maija Kaminska, Dorota Männistö, Ville Kärjä, Vesa Tuomainen, Marjo Hanhineva, Kati Romeo, Stefano Pajukanta, Päivi Pihlajamäki, Jussi de Mello, Vanessa D.. 2021. Nutrients. 13: 3509 -
Light sedation with short habituation time for large-scale functional magnetic resonance imaging studies in rats
Dvoráková, Lenka; Stenroos, Petteri; Paasonen, Ekaterina; Salo, Raimo A.; Paasonen, Jaakko; Gröhn, Olli. 2021. Nmr in biomedicine. 2022; 35: -
MECP2 Increases the Pro-Inflammatory Response of Microglial Cells and Phosphorylation at Serine 423 Regulates Neuronal Gene Expression upon Neuroinflammation
Wittrahm, Rebekka; Takalo, Mari; Marttinen, Mikael; Kuulasmaa, Teemu; Mäkinen, Petra; Kemppainen, Susanna; Martiskainen, Henna; Rauramaa, Tuomas; Pike, Ian; Leinonen, Ville; Natunen, Teemu; Haapasalo, Annakaisa; Hiltunen, Mikko. 2021. Cells. 10: 860 -
Transfer Learning in Magnetic Resonance Brain Imaging: A Systematic Review
Valverde, Juan Miguel; Imani, Vandad; Abdollahzadeh, Ali; De Feo, Riccardo; Prakash, Mithilesh; Ciszek, Robert; Tohka, Jussi. 2021. Journal of imaging. 7: 66