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Microplastics and health

We use and develop several research methods typically used in the field of pharmacy for the needs of microplastics research. We use molecular modeling for molecular level studies of plastics, we develop extraction and sample preparation methods for plastic samples and create analytical methods for NMR and mass spectrometry. The membrane permeability is studied using, among others, the PAMPA-method. We do particle size analysis, microscoping and imaging. In toxicological research we examine, for example, cell viability and inflammation markers.

Piia Bartos (piia.bartos@uef.fi)

I am a pharmaceutical chemist with my research interests now in short non-coding RNA sequences and how to mimic their function using synthetic drugs. My background is in Pharmacy, and I defended my Doctoral thesis in drug design of sirtuins in autumn 2015 in UEF. After my dissertation, I left to study molecular dynamics methods and enzyme engineering to Brno, Czech Republic. I can use all the basic tools of computational drug design, including docking and molecular dynamics simulations and up to some simple quantum chemistry calculations.

Tatu Lajunen (tatu.lajunen@uef.fi)

Tatu got his PhD in Pharmacy from University of Helsinki in 2016. He works on drug delivery to challenging target sites, for example posterior segment of the eye, tumors and central nervous system. Tatu has diverse international research background through working in Santen Pharmaceuticals in Japan as well as Kyoto University and Tokyo University of Pharmacy & Life Sciences. He holds a shared position in University of Helsinki and University of Eastern Finland. The current focus of his research is the utilization of nanoparticle drug delivery systems for targeted treatment of diseases with biomacromolecules. With the help of his international network of collaborators, the work continues to progress the field towards better medications.