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Pekka Jarho

Pekka Jarho

Lecturer

School of Pharmacy, Faculty of Health Sciences

pekka.jarho@uef.fi | +358 40 355 2226

Information Publications

Publications

51/51 items

Farmaseuttinen kemia
Jarho, Pekka; Lahtela-Kakkonen, Maija; Vepsäläinen, Jouko; Rautio, Jarkko; Huttunen, Kristiina; Poso, Antti; Auriola, Seppo. 2023. Publications of the University of Eastern Finland. General series. 44: 32-35
Improved ocular delivery of quercetin and resveratrol: A comparative study between binary and ternary cyclodextrin complexes
Krstić, Luna; Jarho, Pekka; Ruponen, Marika; Urtti, Arto; González-García, María J.; Diebold, Yolanda. 2022. International journal of pharmaceutics. 624:
A scaffold replacement approach towards new sirtuin 2 inhibitors
Seifert, T; Malo, M; Kokkola, T; Stéen, EJL; Meinander, K; Wallén, EAA; Jarho, EM; Luthman, K. 2019. Bioorganic and medicinal chemistry. 2020; 28: 115231
Effect of storage on the dissolution rate of a fast-dissolving perphenazine/&#946 -cyclodextrin complex
Turunen Elina, Korhonen Ossi, Lehto Vesa-Pekka, Kauppinen Ari, Ahtiainen Hanne, Järvinen Kristiina, Jarho Pekka. 2013. Journal of pharmacy and pharmacology. 2014:66: 367-377
The effect of hydroxypropyl-beta-cyclodextrin and sucrose on the sublingual absorption of midazolam in rabbits
Kaartama Ruut, Turunen Elina, Toljamo Kirsi, Kokki Hannu, Lehtonen Marko, Ranta Veli-Pekka, Savolainen Jouko, Järvinen Kristiina, Jarho Pekka. 2012. European journal of pharmaceutics and biopharmaceutics. 81: 178-183
Determination of midazolam and 1-hydroxymidazolam from plasma by gas chromatography coupled to methane negative chemical ionization mass spectrometry after sublingual administration of midazolam
Kaartama Ruut, Jarho Pekka, Savolainen Jouko, Kokki Hannu, Lehtonen Marko. 2011. Journal of chromatography b: analytical technologies in the biomedical and life sciences. 879: 1668 - 1676
Fast-dissolving sublingual solid dispersion and cyclodextrin complex increase the absorption of perphenazine in rabbits
Turunen Elina, Mannila Janne, Laitinen Riikka, Riikonen Joakim, Lehto Vesa-Pekka, Järvinen Tomi, Ketolainen Jarkko, Järvinen Kristiina, Jarho Pekka. 2011. Journal of pharmacy and pharmacology. 63: 19 - 25
Preface: First European cyclodextrin conference
Larsen Kim L, Loftsson Thorsteinn, Mazzaglia Antonino, Jarho Pekka. 2011. Journal of Inclusion Phenomena and Macrocyclic Chemistry. 69: 295
An optical method for continuous monitoring of the dissolution rate of pharmaceutical powders
Laitinen R, Lahtinen J, Silfsten P, Vartiainen E, Jarho P & Ketolainen J. 2010. Journal of pharmaceutical and biomedical analysis. 52: 181 - 189
Cyclodextrins and chitosan derivatives in sublingual delivery of low solubility peptides: A study using cyclosporin A, alpha-cyclodextrin and quaternary chitosan N-betainate
Mannila J, Järvinen K, Holappa J, Matilainen L, Auriola S, Jarho P. 2009. International journal of pharmaceutics. 381: 19-24
Development and validation of a gas chromatographic-mass spectrometric method for quantitative determination of perphenazine in rabbit plasma after sublingual administration
Turunen E, Lehtonen M, Järvinen T, Jarho P. 2008. Journal of chromatography b: analytical technologies in the biomedical and life sciences. 872: 51-57
In vitro toxicity and permeation of cyclodextrins in Calu-3 cells
Matilainen L, Toropainen T, Vihola H, Hirvonen J, Järvinen T, Jarho P, Järvinen K. 2008. Journal of controlled release. 126: 10-16
Lääkepäivät - Lääkkeitä myös terveille?. 25.-26.4.2008 Kuopio
Jarho P. 2008. Kuopion yliopiston julkaisuja A. Farmaseuttiset tieteet. . -
Quantitative analysis of natural cyclodextrins by high-performance liquid chromatography with pulsed amperometric detection: Application to cell permeation study
Toropainen T, Jarho P, Lehtonen M, Keski-Rahkonen P, Raatikainen H, Järvinen T. 2008. Journal of chromatography b: analytical technologies in the biomedical and life sciences. 867: 90-98
The effect of cyclodextrins on chemical and physical stability of glucagon and characterization of glucagon/gamma-CD inclusion complexes
Matilainen L, Lambertsen Larsen K, Wimmer R, Keski-Rahkonen P, Auriola S, Järvinen T, Jarho P. 2008. Journal of pharmaceutical sciences. 97: 2720-2729
Crystal structure changes of gamma-cyclodextrin after the SEDS process in supercritical carbon dioxide affect the dissolution rate of complexed budesonide
Toropainen T, Heikkilä T, Leppänen J, Matilainen L, Velaga S, Jarho P, Carlfors J, Lehto V-P, Järvinen T, Järvinen K. 2007. Pharmaceutical research. 24: 1058-1066
In vitro evaluation of the effect of cyclodextrin complexation on pulmonary deposition of a peptide, cyclosporin A
Matilainen L, Järvinen K, Toropainen T, Näsi E, Auriola S, Järvinen T, Jarho P. 2006. International journal of pharmaceutics. 318: 41-48
Novel methylated cyclodextrin complexes
Järvinen T, Mannila J, Jarho P. 2006.
Precipitation complexation method produces cannabidiol/beta-cyclodextrin inclusion complex suitable for sublingual administration of cannabidiol
Mannila J, Järvinen T, Järvinen K, Jarho P. 2006. Journal of pharmaceutical sciences. 96: 312-319
Preparation of budesonide/gamma-cyclodextrin complexes in supercritical fluids with a novel SEDS method
Toropainen T, Velaga S, Heikkilä T, Matilainen L, Jarho P, Carlfors J, Lehto V-P, Järvinen T, Järvinen K. 2006. Journal of pharmaceutical sciences. 95: 2235-2245
Sublingual administration of Delta9 -tetrahydrocannabinol/ß-cyclodextrin complex increases the bioavailability of Delta9 -tetrahydrocannabinol in rabbits
Mannila J, Järvinen T, Järvinen K, Tervonen J, Jarho P. 2006. Life sciences. 78: 1911-1914
Cyclodextrins in drug delivery
Loftsson T, Jarho P, Másson M, Järvinen T. 2005. Expert opinion on drug delivery. 2: 335-351
Effects of RM-beta-CD on sublingual bioavailability of Delta9-tetrahydrocannabinol in rabbits
Mannila J, Järvinen T, Järvinen K, Tarvainen M, Jarho P. 2005. European journal of pharmaceutical sciences. 26: 71-77
Lignaanikomplekseja
Järvinen T, Jarho P, Unkila M, Hiilovaara-Teijo M. 2005.
Cyclodextrins in pulmonary drug delivery: in vitro toxicity of cyclodextrins in calu-3 cells
Kinnarinen T, Järvinen K, Jarho P, Vihola H, Hirvonen J, Järvinen T. Teoksessa: (toim.) , 2004. Respiratory Drug Delivery IX. Biological, Pharmaceutical, Clinical, and Regultory Issues Relating to Optimized Drug Delivery by Aerosol. s. 773-776. Davis Healthcare International Publishing, LLC
Determination of delta9 -tetrahydrocannabinol from rabbit plasma by gas chromatography-mass spectrometry using two ionization techniques
Mannila J, Lehtonen M, Järvinen T, Jarho P. 2004. Journal of chromatography b: analytical technologies in the biomedical and life sciences. 810: 283-290
Uudet luonnon syklodekstriinin kompleksit
Jarho P, Mannila J, Järvinen T. 2004.
Pulmonary deposition of a budesonide/gamma-cyclodextrin complex in vitro
Kinnarinen T, Jarho P, Järvinen K, Järvinen T. 2003. Journal of controlled release. 90: 197-205
Uudet metyloidut syklodekstriininkompleksit
Järvinen T, Mannila J, Jarho P. 2003.
The in vitro pulmonary deposition of a budesonide/gamma-cyclodextrin inclusion complex
Kinnarinen T, Jarho P, Järvinen K, Järvinen T. Teoksessa: (toim.) , 2002. Proceedings of the 11th International Cyclodextrin Symposium. s. 97-100. Kluwer Academic Publishers
Complexation with tolbutamide modifies the physicochemical and tableting properties of hydroxypropyl-beta-cyclodextrin
Suihko E, Korhonen O, Järvinen T, Ketolainen J, Jarho P, Laine E, Paronen P. 2001. International journal of pharmaceutics. 215: 137-145
The effect of cyclodextrin and pH on cyclodextrincatalyzed deacetylation of spironolactone
Jarho P, Vander Velde D, Stella VJ. Teoksessa: Szejtli J(toim.) , 2001. Cyclodextrins: From Basic Research to Market. 10th International Cyclodextrin Symposium CD2000. s. 500-505. Mira Digital Publishing
Cyclodextrin-catalyzed deacetylation of spironolactone is pH and cyclodextrin dependent
Jarho P, Vander Velde D, Stella VJ. 2000. Journal of pharmaceutical sciences. 89: 241-249
Effects of aqueous solubility and dissolution characteristics on oral bioavailability of entacapone
Savolainen J, Forsberg M, Taipale H, Männistö PT, Järvinen K, Gynther J, Jarho P, Järvinen T. 2000. Drug development research. 49: 238-244
Syklodekstriinit - perustutkimuksesta lääkkeisiin
Jarho P, Järvinen T. 2000. TABU. : 12-14
Coadministration of a water-soluble polymer increases the usefulness of cyclodextrins in solid oral dosage forms
Savolainen J, Järvinen K, Taipale H, Jarho P, Loftsson T, Järvinen T. Teoksessa: Torres Labandeira JJ, Vila-Jato JL(toim.) , 1999. Proceedings of the Ninth International Symposium on Cyclodextrins. s. 261-264. Kluwer Academic
Co-administration of a water-soluble polymer increases the usefulness of cyclodextrins in solid oral dosage forms
Savolainen J, Järvinen K, Taipale H, Jarho P, Loftsson T, Järvinen T. 1998. Pharmaceutical research. 15: 1696-1701
Hydroxypropyl-beta-cyclodextrin and its combination with hydroxypropyl-methylcellulose increases aqueous solubility of delta9-tetrahydrocannabinol
Jarho P, Pate DW, Brenneisen R, Järvinen T. 1998. Life sciences. 63: 381-384
Syklodekstriinit silmätippaformulaatiossa
Jarho P. 1998. Dosis. 14: 82-86
Beta-cyclodextrin derivatives (2-HP-beta-CD, SBE4-beta-CD) decrease the amphiphilicity and membrane perturbing effects of pilocarpine prodrugs
Saarinen-Savolainen P, Urtti A, Jarho P, Järvinen T. 1997. European journal of pharmaceutical sciences. 5: 89-96
Cyclodextrins in Eyedrop Formulations. Studies with Pilocarpine Prodrugs, Anandamide and Dipivefrine
Jarho P. 1997. Kuopion yliopiston julkaisuja A. Farmaseuttiset tieteet
Effects of Topical alpha-substituted anandamides on intraocular pressure in normotensive rabbits
Pate DW, Järvinen K, Urtti A, Jarho P, Mahadevan V, Järvinen T. 1997. Pharmaceutical research. 14: 1738-1743
The use of cyclodextrins in ophthalmic formulations of dipivefrin
Jarho P, Järvinen K, Urtti A, Stella VJ, Järvinen T. 1997. International journal of pharmaceutics. 153: 225-233
Effects of topical anandamides on intraocular pressure in normotensive rabbits
Pate DW, Järvinen K, Urtti A, Jarho P, Fich M, Mahadevan V, Järvinen T. 1996. Life sciences. 58: 1849-1860
Hydroxypropyl-ß-cyclodextrin increases aqueous solubility and stability of anandamide
Jarho P, Urtti A, Järvinen K, Pate DW, Järvinen T. 1996. Life sciences. 58: 181-185
Increase in aqueous solubility, stability and in vitro corneal permeability of anandamide by hydroxypropyl-ß-cyclodextrin
Jarho P, Urtti A, Pate DW, Suhonen P, Järvinen T. 1996. International journal of pharmaceutics. 137: 209-216
Modified ß-cyclodextrin (SBE7-ß-CyD) with viscous vehicle improves the ocular delivery and tolerability of pilocarpine prodrug in rabbits
Jarho P, Järvinen K, Urtti A, Stella VJ, Järvinen T. 1996. Journal of pharmacy and pharmacology. 48: 263-269
The effect of SBE7-ß-CD with viscous vehicle on ocular delivery of pilocarpine prodrug in rabbits
Jarho P, Järvinen K, Urtti A, Stella VJ, Järvinen T. Teoksessa: Szejtli J, Szente L(toim.) , 1996. Proceedings of the Eighth International Symposium on Cyclodextrons. s. 399-402. Kluwer
The effects of HP-ß-CD on aqueous solubility, stability and in vitro corneal penetration of anandamide
Jarho P, Urtti A, Pate DW, Suhonen P, Järvinen T. Teoksessa: Szejtli J, Szente L(toim.) , 1996. Proceedings of the Eight International Symposium on Cyclodextrons. s. 395-398. Kluwer
Hydroxypropyl-ß-cyclodextrin increases the aqueous solubility and stability of pilocarpine prodrugs
Jarho P, Urtti A, Järvinen T. 1995. Pharmaceutical research. 12: 1371-1375
Ophthalmic arachidonylethanolamide decreases intraocular pressure in normotensive rabbits
Pate DW, Järvinen K, Urtti A, Jarho P, Järvinen T. 1995. Current eye research. 14: 791-797

University of Eastern Finland Joensuu, Kuopio © University of Eastern Finland

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Pekka Jarho

Farmaseuttinen kemia

Improved ocular delivery of quercetin and resveratrol: A comparative study between binary and ternary cyclodextrin complexes

A scaffold replacement approach towards new sirtuin 2 inhibitors

Effect of storage on the dissolution rate of a fast-dissolving perphenazine/&#946 -cyclodextrin complex

The effect of hydroxypropyl-beta-cyclodextrin and sucrose on the sublingual absorption of midazolam in rabbits

Determination of midazolam and 1-hydroxymidazolam from plasma by gas chromatography coupled to methane negative chemical ionization mass spectrometry after sublingual administration of midazolam

Fast-dissolving sublingual solid dispersion and cyclodextrin complex increase the absorption of perphenazine in rabbits

Preface: First European cyclodextrin conference

An optical method for continuous monitoring of the dissolution rate of pharmaceutical powders

Cyclodextrins and chitosan derivatives in sublingual delivery of low solubility peptides: A study using cyclosporin A, alpha-cyclodextrin and quaternary chitosan N-betainate

Development and validation of a gas chromatographic-mass spectrometric method for quantitative determination of perphenazine in rabbit plasma after sublingual administration

In vitro toxicity and permeation of cyclodextrins in Calu-3 cells

Lääkepäivät - Lääkkeitä myös terveille?. 25.-26.4.2008 Kuopio

Quantitative analysis of natural cyclodextrins by high-performance liquid chromatography with pulsed amperometric detection: Application to cell permeation study

The effect of cyclodextrins on chemical and physical stability of glucagon and characterization of glucagon/gamma-CD inclusion complexes

Crystal structure changes of gamma-cyclodextrin after the SEDS process in supercritical carbon dioxide affect the dissolution rate of complexed budesonide

In vitro evaluation of the effect of cyclodextrin complexation on pulmonary deposition of a peptide, cyclosporin A

Novel methylated cyclodextrin complexes

Precipitation complexation method produces cannabidiol/beta-cyclodextrin inclusion complex suitable for sublingual administration of cannabidiol

Preparation of budesonide/gamma-cyclodextrin complexes in supercritical fluids with a novel SEDS method

Sublingual administration of Delta9 -tetrahydrocannabinol/ß-cyclodextrin complex increases the bioavailability of Delta9 -tetrahydrocannabinol in rabbits

Cyclodextrins in drug delivery

Effects of RM-beta-CD on sublingual bioavailability of Delta9-tetrahydrocannabinol in rabbits

Lignaanikomplekseja

Cyclodextrins in pulmonary drug delivery: in vitro toxicity of cyclodextrins in calu-3 cells

Determination of delta9 -tetrahydrocannabinol from rabbit plasma by gas chromatography-mass spectrometry using two ionization techniques

Uudet luonnon syklodekstriinin kompleksit

Pulmonary deposition of a budesonide/gamma-cyclodextrin complex in vitro

Uudet metyloidut syklodekstriininkompleksit

The in vitro pulmonary deposition of a budesonide/gamma-cyclodextrin inclusion complex

Complexation with tolbutamide modifies the physicochemical and tableting properties of hydroxypropyl-beta-cyclodextrin

The effect of cyclodextrin and pH on cyclodextrincatalyzed deacetylation of spironolactone

Cyclodextrin-catalyzed deacetylation of spironolactone is pH and cyclodextrin dependent

Effects of aqueous solubility and dissolution characteristics on oral bioavailability of entacapone

Syklodekstriinit - perustutkimuksesta lääkkeisiin

Coadministration of a water-soluble polymer increases the usefulness of cyclodextrins in solid oral dosage forms

Co-administration of a water-soluble polymer increases the usefulness of cyclodextrins in solid oral dosage forms

Hydroxypropyl-beta-cyclodextrin and its combination with hydroxypropyl-methylcellulose increases aqueous solubility of delta9-tetrahydrocannabinol

Syklodekstriinit silmätippaformulaatiossa

Beta-cyclodextrin derivatives (2-HP-beta-CD, SBE4-beta-CD) decrease the amphiphilicity and membrane perturbing effects of pilocarpine prodrugs

Cyclodextrins in Eyedrop Formulations. Studies with Pilocarpine Prodrugs, Anandamide and Dipivefrine

Effects of Topical alpha-substituted anandamides on intraocular pressure in normotensive rabbits

The use of cyclodextrins in ophthalmic formulations of dipivefrin

Effects of topical anandamides on intraocular pressure in normotensive rabbits

Hydroxypropyl-ß-cyclodextrin increases aqueous solubility and stability of anandamide

Increase in aqueous solubility, stability and in vitro corneal permeability of anandamide by hydroxypropyl-ß-cyclodextrin

Modified ß-cyclodextrin (SBE7-ß-CyD) with viscous vehicle improves the ocular delivery and tolerability of pilocarpine prodrug in rabbits

The effect of SBE7-ß-CD with viscous vehicle on ocular delivery of pilocarpine prodrug in rabbits

The effects of HP-ß-CD on aqueous solubility, stability and in vitro corneal penetration of anandamide

Hydroxypropyl-ß-cyclodextrin increases the aqueous solubility and stability of pilocarpine prodrugs

Ophthalmic arachidonylethanolamide decreases intraocular pressure in normotensive rabbits