EMILIA KANSANEN

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Publications

• Linna-Kuosmanen, Suvi; Bosch, Vanesa Tomas; Moreau, Pierre R; Bouvy-Liivrand, Maria; Niskanen, Henri; Kansanen, Emilia; Kivelä, Annukka; Hartikainen, Juha; Hippeläinen, Mikko; Kokki, Hannu; Tavi, Pasi; Levonen, Anna-Liisa; Kaikkonen, Minna U. 2021. NRF2 is a key regulator of endothelial microRNA expression under proatherogenic stimuli Cardiovascular research 117 5: 1339-1357. 2021
• Jobbagy, Soma; Vitturi, Dario A; Salvatore, Sonia R; Turell, Lucía; Pires, Maria F; Kansanen, Emilia; Batthyany, Carlos; Lancaster, Jack R Jr; Freeman, Bruce A; Schopfer, Francisco. 2018. Electrophiles modulate glutathione reductase activity via alkylation and upregulation of glutathione biosynthesis Redox biology 2019; 21: 101050. 2018
• Kansanen Emilia, Kuosmanen Suvi M, Ruotsalainen Anna-Kaisa, Hynynen Heidi, Levonen Anna-Liisa. 2017. Nitro-Oleic Acid Regulates Endothelin Signaling in Human Endothelial Cells. MOLECULAR PHARMACOLOGY 92 4: 481-490. 2017
• Kuosmanen SM, Kansanen E, Kaikkonen MU, Sihvola V, Pulkkinen K, Jyrkkänen H-K, Tuoresmäki P, Hartikainen J, Hippeläinen M, Kokko H, Tavi P, Heikkinen S, Levonen A-M. 2017. NRF2 regulates endothelial glycolysis and proliferation with miR-93 and mediates the effects of oxidized phospholipids on endothelial activation. NUCLEIC ACIDS RESEARCH 2018; 46 3: 1124-1138. 2017
• Kuosmanen Suvi M, Kansanen Emilia, Sihvola Virve, Levonen Anna-Liisa. 2017. MicroRNA Profiling Reveals Distinct Profiles for Tissue-Derived and Cultured Endothelial Cells. Scientific Reports 7: 10943. 2017
• Kansanen Emilia, Levonen Anna-Liisa. 2015. Oxidized and Nitrated Lipid Interactions with the Keap1-Nrf2 Pathway. In: Corinne M. Spickett, Henry Jay Forman (ed.) Lipid Oxidation in Health and Disease. CRC PRESS. s. 255-277. 2015
• Savinainen Juha R, Kansanen Emilia, Pantsar Tatu, Navia-Paldanius Dina, Parkkari Teija, Lehtonen Marko, Laitinen Tuomo, Nevalainen Tapio, Poso Antti, Levonen Anna-Liisa, Laitinen Jarmo T. 2014. Robust hydrolysis of prostaglandin glycerol esters by human monoacylglycerol lipase (MAGL). MOLECULAR PHARMACOLOGY Epub ahead of print: -. 2014
• Kansanen Emilia, Kuosmanen Suvi M, Leinonen Hanna, Levonen Anna-Liisa. 2013. The Keap1-Nrf2 pathway: Mechanisms of activation and dysregulation in cancer. Redox Biology Volume 1, Issue 1, 2013: 45-49. 2013
• Kansanen, Emilia. 2012. Lipid Oxidation and Nitration Products as Activators of Cytoprotective Nrf2 Signaling in the Endothelium. Itä-Suomen yliopisto. Publications of the University of Eastern Finland. Dissertations in Health Sciences 91. 2012
• Kansanen E, Jyrkkänen HK, Levonen AL. 2011. Activation of stress signaling pathways by electrophilic oxidized and nitrated lipids. FREE RADICAL BIOLOGY & MEDICINE 2012 Mar 15;52(6 2011 Dec 13. [Epub ahead of print]: 973-82. 2011
• Kansanen Emilia, Bonacci Gustavo, Schopfer Francisco J, Kuosmanen Suvi M, Tong Kit I, Leinonen Hanna, Woodcock Steven R, Yamamoto Masayuk, Carlberg Carsten, Ylä-Herttuala Seppo, Freeman Bruce A, Levonen Anna-Liisa. 2011. Electrophilic nitro-fatty acids activate NRF2 by a KEAP1 cysteine 151-independent mechanism. JOURNAL OF BIOLOGICAL CHEMISTRY 286: 14019-14027. 2011
• Kansanen E, Jyrkkänen H-K, Volger OL, Leinonen H, Kivelä AM, Häkkinen S-K, Woodcock SR, Schopfer FJ, Horrevoets AJ, Ylä-Herttuala S, Freeman BA, Levonen A-L. 2009. Nrf2-dependent and -independent responses to nitro-fatty acids in human endothelial cells: identification of heat shock response as the major pathway activated by nitro-oleic acid. JOURNAL OF BIOLOGICAL CHEMISTRY 284 48: 33233-33241. 2009
• Jyrkkänen H-K, Kansanen E, Inkala M, Kivelä AM, Hurttila H, Heinonen SE, Goldsteins G, Jauhiainen S, Tiainen S, Makkonen H, Oskolkova O, Afonyushkin T, Koistinaho J, Yamamoto M, Bochkov VN, Ylä-Herttuala S, Levonen A-L. 2008. Nrf2 regulates antioxidant gene expression evoked by oxidized phospholipids in endothelial cells and murine arteries in vivo CIRCULATION RESEARCH [ONLINE: HTTP://CIRCRES.AHAJOURNALS.ORG/] 103: e1-e9. 2008