HEIKKI KOSKELA

Contact info

Research groups - UEF

• 
  Prolonged cough research group

Publications

• Koskela Heikki O; Lätti, Anne M. 2021. Sputum production in chronic cough increases the probability of asthma: a cross-sectional questionnaire study ERJ open research 7 2: 00086-2021. 2021
• Koskela, Heikki Olavi; Nurmi, Hanna Maria; Surinder, Singh Birring. 2021. Utility of Cough Provocation Tests in Chronic Cough and Respiratory Diseases: A Comprehensive Review and Introduction of New Reference Ranges for the Capsaicin Test Allergy asthma & immunology research 13 6: 833-849. 2021
• Koskela, Heikki. 2021. Miksi aikuisen yskä pitkittyy? Duodecim 137 19: 2045-2050. 2021
• Koskela, Heikki O.; Nurmi, Hanna M.; Song, Woo-Jung. 2021. Deep Inspiration-Provoked Cough: A Sign of Cough Reflex Arc Hypersensitivity Lung 199 5: 501-505. 2021
• Chang, RYK; Kwok, PCL; Ghassabian, S; Brannan, JD; Koskela, HO; Chan, H-K. 2020. Cough as an adverse effect on inhalation pharmaceutical products British journal of pharmacology 177 18: 4096-4112. 2020
• Koskela, Heikki O; Selander, Tuomas A; Lätti, Anne M. 2020. Cluster analysis in 975 patients with current cough identifies a phenotype with several cough triggers, many background disorders, and low quality of life Respiratory research 21: 219. 2020
• Koskela, Heikki; Nurmi, Hanna; Purokivi, Minna. 2020. Cough-provocation tests with hypertonic aerosols ERJ open research 6 2: 1-12. 2020
• Lätti, Anne M; Pekkanen, Juha; Koskela, Heikki O. 2020. Persistence of chronic cough in a community-based population ERJ open research 6 2: 00229-2019. 2020
• Nurmi, Hanna; Koskela, Heikki. 2020. Pitkittynyttä yskää sairastava potilas yleislääkärin vastaanotolla Yleislääkäri 35 2: 9-12. 2020
• Koskela, Heikki; Tikkakoski, Antti; Karjalainen, Jussi; Mäkelä, Mika; Malmberg, Pekka. 2019. Epäsuorat altistuskokeet astman diagnostiikassa Duodecim 138 18: 1787-1794. 2019
• Uusitalo, Arja; Lindström, Irmeli; Karjalainen, Jussi; Kauppi, Paula; Koskela, Heikki; Suojalehto, Hille. 2019. Pelastustyöntekijän astma Duodecim 135 18: 1795-1801. 2019
• Nurmi, Hanna M; Lätti, Anne M; Brannan, John D; Koskela, Heikki O. 2019. Comparison of mannitol and citric acid cough provocation tests Respiratory medicine 158: 14-20. 2019
• Lätti, AM; Pekkanen, J; Koskela, HO. 2019. Predictors of prolongation in recent-onset cough ERJ open research 5 2: 00238-2018. 2019
• Koskela, HO; Lätti, AM; Pekkanen, J. 2019. Subfreezing air as a cough trigger and multiple triggers are strongly associated with the presence of asthma in chronic cough Respiratory medicine 153: 26-30. 2019
• Koskela, Heikki; Tikkakoski, Antti; Karjalainen, Jussi; Mäkelä, Mika; Malmberg, Pekka. 2019. Epäsuorat altistuskokeet astman diagnosoinnissa Duodecim 135 18: 1787-1794. 2019
• Koskela, Heikki Olavi; Lätti, Anne. 2019. On aika ymmärtää yskää Lääkärilehti 74 39: 2135. 2019
• Koskela, Heikki Olavi; Lätti, Anne. 2019. On aika kuunnella yskää Lääkärilehti 74 39: 2135. 2019
• Koskela, Heikki O; Lätti, Anne M; Pekkanen, Jukka. 2019. Risk factors for repetitive doctor's consultations due to cough: a cross-sectional study in a Finnish employed population . BMJ open 9 6: e030945. 2019
• Koskela, Heikki. 2019. Erikoislääkäripula ei poistu nykyresurssein Lääkärilehti 74 32: 1650. 2019
• Lätti, Anne M; Pekkanen, Juha; Koskela, Heikki O. 2018. Defining the risk factors for acute, subacute and chronic cough: a cross-sectional study in a Finnish adult employee population . BMJ Open 8 7: e022950. 2018
• Malmberg, Pekka; Karjalainen, Jussi; Tikkakoski, Antti; Mäkelä, Mika; Koskela, Heikki. 2018. Keuhkoputkien supistumisherkkyyden mittaus metakoliinialtistuksella - Suomen Kliinisen Fysiologian yhdistyksen ja Suomen Keuhkolääkäriyhdistyksen ja Suomen Lastenlääkäreiden Allergologiayhdistyksen suositus Lääkärilehti 73 23: 1511-1513. 2018
• Koskela, Heikki O; Lätti, Anne M; Pekkanen, Juha. 2018. The impacts of cough: a cross-sectional study in a Finnish adult employee population ERJ open research 4 4: 00113. 2018
• Koskela, Heikki O; Lake, Clair; Wong, Keith; Brannan, John D. 2018. Cough sensitivity to mannitol inhalation challenge identifies subjects with chronic cough European respiratory journal 51 5: 1800294. 2018
• Harju Terttu, Koskela Heikki. 2017. Interstitiaaliset keuhkomuutokset sidekudossairauksissa - perussairaus, lääkehaitta vai infektio?. SUOMEN LÄÄKÄRILEHTI 72 38: 2091-2096. 2017
• Koskela Heikki O, Lätti Anne M, Purokivi Minna K. 2017. Long-term prognosis of chronic cough : a prospective, observational cohort study BMC PULMONARY MEDICINE 17 1: 146. 2017
• Koskela Heikki, Naaranlahti Toivo. 2016. Yskän lääkehoito. DUODECIM 132 5: 455-60. 2016
• Koskela HO, Purokivi MK, Kokkarinen J. 2016. Stepping down from combination asthma therapy: the predictors of outcome. RESPIRATORY MEDICINE 117: 109-115. 2016
• Koskela Heikki O, Salonen Päivi H, Romppanen Jarkko, Hartikainen Juha. 2015. Plasma amino-terminal pro B-type natriuretic peptide as a predictor of late cardiovascular mortality in patients with acute lung disorders: a prospective, observational cohort study. ESC Heart Failure 2 2: 69-75. 2015
• Koskela Heikki O, Salonen Päivi H, Romppanen Jarkko, Niskanen Leo. 2015. A history of diabetes but not hyperglycaemia during exacerbation of obstructive lung disease has impact on long-term mortality: a prospective observational cohort study. BMJ Open 5 1: e006794. 2015
• Lampi Jussi, Koskela Heikki, Hartikainen Anna-Liisa, Ramasamy Adaikalavan, Couto Alves Alexessander, Järvelin Marjo-Riitta, Pekkanen Juha. 2015. Farm environment during infancy and lung function at the age of 31: a prospective birth cohort study in Finland. BMJ Open 5 7: e007350. 2015
• Rutanen J, Kononoff A, Arstila L, Elfving P, Koskela H, Kaipiainen-Seppänen O. 2014. Five cases of interstitial lung disease after leflunomide was combined with methotrexate therapy. SCANDINAVIAN JOURNAL OF RHEUMATOLOGY 43: 254-258. 2014
• Koskela Heikki, Purokivi Minna. 2014. Pitkittynyt yskä: tavallinen vaiva, tyytymätön potilas. DUODECIM 130 18: 1827-1833. 2014
• Koskela Heikki O, Salonen Päivi H, Romppanen Jarkko, Niskanen Leo. 2014. Long-term mortality after community-acquired pneumonia - impacts of diabetes and newly discovered hyperglycaemia: a prospective, observational cohort study. BMJ Open 4 8: e005715. 2014
• Salonen Päivi H, Koskela Heikki O, Niskanen Leo. 2013. Prevalence and determinants of hyperglycaemia in pneumonia patients. SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES 45 2: 88-94. 2013
• Koskela HO, Purokivi MK, Nieminen RM, Moilanen E. 2012. Asthmatic cough and airway oxidative stress RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY 181: 346-350. 2012
• Väisänen T, Hämäläinen S, Koivula I, Koskela H. 2012. Nuoren miehen Mycoplasma penumoniae - infektio ja limakalvoille rajoittunut Stevens-Johnsonin oireyhtymä. DUODECIM 128 21: 2272-2276. 2012
• Koskela H, Purokivi M. 2011. Hypertonisen suolan inhalaatio: lupaava hoitomuoto bronkiektasiataudissa DUODECIM 127: 2653-2659. 2011
• Koskela H. 2011. Empyeeman hoito DUODECIM 127: 191-196. 2011
• Purokivi M, Koskela H, Brannan JD, Kontra K. 2011. Cough response to isocapnic hyperpnoea of dry air and hypertonic saline are interrelated COUGH [ONLINE] 7: 8. 2011
• Koskela HO. 2009. Do we need more than one bronchial provocation test in order to diagnose asthma?. CLINICAL AND EXPERIMENTAL ALLERGY 39: 940-942. 2009
• Koskela HO. 2009. Pitkäaikainen happihoito: paljon toiveita, vähän näyttöjä. DUODECIM 125: 1177-1183. 2009
• Koskela HO, Purokivi MK, Kontra KM, Taivainen AH, Tukiainen HO. 2008. Hypertonic saline cough provocation test with salbumatol pre-treatment: evidence for sensorineural dysfunction in asthma. CLINICAL AND EXPERIMENTAL ALLERGY 38: 1100-1107. 2008
• Koskela HO, Purokivi MK, Tukiainen RM. 2008. Simultaneous versus video counting of coughs in hypertonic cough challenges. COUGH [ONLINE] 4 8: [6]. 2008
• Purokivi M, Koskela HO, Koistinen T, Magga J, Peuhkurinen K, Kiviniemi V, Kontra KM. 2008. Utility of cough response during hypertonic histamine challenge in diagnosing asthma. RESPIRATORY MEDICINE 102: 1379-1384. 2008
• Purokivi M, Tacke U, Koskela H, Kokkarinen J, Leutola H. 2008. Äkillinen hengitysvajaus - metadonikorvaushoidon aloittamiseen liittyvä harvinainen haittavaikutus. DUODECIM 124: 1753-1756. 2008
• Purokivi M, Koskela HO, Koistinen T, Magga J, Peuhkurinen K, Kiviniemi V, Kontra KM. 2007. Utility of hypertonic histamine challenge in distinguishing difficult-to-diagnose asthma. CLINICAL RESPIRATORY JOURNAL 1: 91-98. 2007
• Koskela HO. 2007. Cold air-provoked respiratory symptoms: the mechanisms and management. INTERNATIONAL JOURNAL OF CIRCUMPOLAR HEALTH 66: 91-100. 2007
• Brannan JD, Koskela H, Anderson SD. 2007. Monitoring asthma therapy using indirect bronchial provocation tests. CLINICAL RESPIRATORY JOURNAL 1: 3-15. 2007
• Koskela H, Kaipiainen-Seppänen O. 2006. Amyopaattiseen dermatomyosiittiin liittyvä interstitiaalinen keuhkosairaus. DUODECIM 122: 2349-2351. 2006
• Koskela HO, Kiviniemi V, Purokivi MK, Taivainen AH, Tukiainen HO. 2006. Determinants of the bronchodilation response to salbutamol on histamine-induced bronchoconstriction. RESPIRATORY MEDICINE 100: 1760-1766. 2006
• Pelkonen M, Notkola I-L, Nissinen A, Tukiainen H, Koskela H. 2006. Thirty-year cumulative incidence of chronic bronchitis and COPD in relation to 30-year pulmonary function and 40-year mortality: A follow-up in middle-aged rural men. CHEST 130: 1129-1137. 2006
• Anderson SD, Brannan JD, Leuppi JD, Koskela H. 2005. Monitoring airway hyperresponsiveness: Indirect stimuli - exercise, hypertonic saline, mannitol, and adenosine monophosphate. In: Gibson PG (ed.) Monitoring Asthma. Taylor & Francis Group. s. 275-323. 2005
• Koskela HO, Happonen KK, Remes ST, Pekkanen J. 2005. Effect of farming environment on sensitisation to allergens continues after childhood. OCCUPATIONAL AND ENVIRONMENTAL MEDICINE 62: 607-611. 2005
• Remes ST, Koskela HO, Iivanainen K, Pekkanen J. 2005. Allergen-specific sensitization in asthma and allergic diseases in children: the study on farmers' and non-farmers' children. CLINICAL AND EXPERIMENTAL ALLERGY 35: 160-166. 2005
• Valtonen J, Hakala T, Koskela H, Pirinen R, Mäkinen K. 2004. Keuhkopussin paikallinen sidekudoskasvain. DUODECIM 120: 1490-1493. 2004
• Koskela H, Taivainen A, Tukiainen H, Chan H-K. 2003. Inhalation challenge with bovine dander allergens: Who needs it?. CHEST 124: 383-391. 2003
• Nikolajev K, Korppi M, Koskela H, Remes K, Jokela V, Länsimies E, Heinonen K. 2002. Methacholine, cold air and exercise challenge tests in the diagnosis of bronchial responsiveness at school age: A follow-up study from birth to school age. ALLERGOLOGY INTERNATIONAL 51: 131-138. 2002
• Nikolajev K, Heinonen K, Koskela H, Korppi M, Länsimies E, Jokela V. 1999. Determinants of bronchial responsiveness at school age in prematurely born children. PEDIATRIC PULMONOLOGY 28: 408-413. 1999
• Koskela H, Pihlajamäki J, Pekkarinen H, Tukiainen H. 1998. Effect of cold air on exercise capacity in COPD. Increase or decrease?. CHEST 113: 1560-1565. 1998
• Koskela H. 1997. Effects of Cold Air on Lung Function in Obstructive Lung Diseases. The Roles of Direct Airways Effects and Cutaneous Reflex Mechanisms. Kuopion yliopiston julkaisuja D. Lääketiede. 1997
• Koskela HO, Räsänen SH, Tukiainen HO. 1997. The diagnostic value of cold air hyperventilation in adults with suspected asthma. RESPIRATORY MEDICINE 91 8: 470-478. 1997
• Koskela HO, Koskela AK, Tukiainen HO. 1996. Bronchoconstriction due to cold weather in COPD*. The roles of direct airway effects and cutaneous reflex mechanisms. CHEST 110 3: 632-636. 1996
• Koskela H, Tukiainen H. 1995. Facial cooling, but not nasal breathing of cold air, induces bronchoconstriction: a study in asthmatic and healthy subjects. EUROPEAN RESPIRATORY JOURNAL 8 12: 2088-2093. 1995