Kirsi Virtanen - UEFConnect

Cold-stimulated brown adipose tissue activation is related to changes in serum metabolites relevant to NAD+ metabolism in humans

U-Din, Mueez; de Mello, Vanessa D; Tuomainen, Marjo; Raiko, Juho; Niemi, Tarja; Fromme, Tobias; Klåvus, Anton; Gautier, Nadine; Haimilahti, Kimmo; Lehtonen, Marko; Kristiansen, Karsten; Newman, John W; Pietiläinen, Kirsi H; Pihlajamäki, Jussi; Amri, Ez-Zoubir; Klingenspor, Martin; Nuutila, Pirjo; Pirinen, Eija; Hanhineva, Kati; Virtanen, Kirsi A. 2023. Cell reports. 42:

Defective extracellular matrix remodeling in brown adipose tissue is associated with fibro-inflammation and reduced diet-induced thermogenesis

Pellegrinelli, Vanessa; Figueroa-Juárez, Elizabeth; Samuelson, Isabella; U-Din, Mueez; Rodriguez-Fdez, Sonia; Virtue, Samuel; Leggat, Jennifer; Çubuk, Cankut; Peirce, Vivian J.; Niemi, Tarja; Campbell, Mark; Rodriguez-Cuenca, Sergio; Blázquez, Joaquin Dopazo; Carobbio, Stefania; Virtanen, Kirsi A.; Vidal-Puig, Antonio. 2023. Cell reports. 42: . 112640

Liraglutide demonstrates a therapeutic effect on mitochondrial dysfunction in human SGBS adipocytes in vitro

Vaittinen, Maija; Ilha, Mariana; Herbers, Elena; Wagner, Anita; Virtanen, Kirsi A; Pietiläinen, Kirsi H; Pirinen, Eija; Pihlajamäki, Jussi. 2023. Diabetes research and clinical practice. 199:

Brown fat triglyceride content is associated with cardiovascular risk markers in adults from a tropical region

Monfort-Pires, Milena; Regeni-Silva, Giulianna; Dadson, Prince; Nogueira, Guilherme A; U-Din, Mueez; Ferreira, Sandra R G; Sapienza, Marcelo Tatit; Virtanen, Kirsi A; Velloso, Licio A. 2022. Frontiers in endocrinology. 13: . 919588

Novel Effects of the Gastrointestinal Hormone Secretin on Cardiac Metabolism and Renal

Laurila, Sanna; Rebelos, Eleni; Lahesmaa, Minna; Sun, Lihua; Schnabl, Katharina; Peltomaa, Tia-Mari; Klén, Riku; U-Din, Mueez; Honka, Miikka-Juhani; Eskola, Olli; Kirjavainen, Anna K; Nummenmaa, Lauri; Klingenspor, Martin; Virtanen, Kirsi A.; Nuutila, Pirjo. 2022. American journal of physiology : endocrinology and metabolism. 322: E54-E62

Obesity-associated Blunted Subcutaneous Adipose Tissue Blood Flow After Meal Improves After Bariatric Surgery

Saari, Teemu; Koffert, Jukka; Honka, Henri; Kauhanen, Saila; U-Din, Mueez; Wierup, Nils; Lindqvist, Andreas; Groop, Leif; Virtanen, Kirsi A; Nuutila, Pirjo. 2022. Journal of clinical endocrinology and metabolism. 107: 1930-1938

The FADS1 rs174550 Genotype Modifies the n‐3 and n‐6 PUFA and Lipid Mediator Responses to a High Alpha‐Linolenic Acid and High Linoleic Acid Diets

Meuronen, Topi; Lankinen, Maria A; Kolmert, Johan; Laaksonen, Vanessa de Mello; Sallinen, Taisa; Ågren, Jyrki; Virtanen, Kirsi A; Laakso, Markku; Wheelock, Craig E; Pihlajamäki, Jussi; Schwab, Ursula. 2022. Molecular nutrition and food research. 66:

Brown adipose tissue fat-fraction is associated with skeletal muscle adiposity

Ogawa, Madoka; Koskensalo, Kalle; Laurila, Sanna; Holstila, Milja; Lahesmaa, Minna; Virtanen, Kirsi A.; Iida, Hidehiro; Akima, Hiroshi; Nuutila, Pirjo. 2021. European journal of applied physiology. 2022; 122: 81-90

Differential Mitochondrial Gene Expression in Adipose Tissue Following Weight Loss Induced by Diet or Bariatric Surgery

van der Kolk, Birgitta; Muniandy, Maheswary; Kaminska, Dorota; Alvarez, Marcus; Ko, Arthur; Miao, Zong; Valsesia, Armand; Langin, Dominique; Vaittinen, Maija; Pääkkönen, Mirva; Jokinen, Riikka; Kaye, Sanna; Heinonen, Sini; Virtanen, Kirsi A; Andersson, Daniel; Männistö, Ville; Saris, Wim; Astrup, Arne; Rydén, Mikael; Blaak, Ellen; Pajukanta, Päivi; Pihlajamäki, Jussi; Pietiläinen, Kirsi H. 2021. Journal of clinical endocrinology and metabolism. 106: 1312-1324

Editorial: Brown Adipose Tissue: From Heat Production in Rodents to Metabolic Health in Humans

Chondronikola, Maria; Bartelt, Alexander; Vidal-Puig, Antonio; Virtanen, Kirsi A. 2021. Frontiers in endocrinology. 12: 1-3

Fatal complications after an interrupted gastric bypass operation in a patient with non-alcoholic fatty liver disease and massive obesity: a case report

Käkelä, Pirjo; Rantanen, Tuomo; Paajanen, Hannu; Virtanen, Kirsi A. 2021. Journal of surgical case reports. : rjab247

Insulin Resistance Is Associated With Enhanced Brain Glucose Uptake During Euglycemic Hyperinsulinemia: A Large-Scale PET Cohort

Rebelos, Eleni; Bucci, Marco; Karjalainen, Tomi; Oikonen, Vesa; Bertoldo, Alessandra; Hannukainen, Jarna C.; Virtanen, Kirsi A.; Latva-Rasku, Aino; Hirvonen, Jussi; Heinonen, Ilkka; Parkkola, Riitta; Laakso, Markku; Ferrannini, Ele; Iozzo, Patricia; Nummenmaa, Lauri; Nuutila, Pirjo. 2021. Diabetes care. 44: 788-794

Secretin activates brown fat and induces satiation

Laurila, Sanna; Sun, Lihua; Lahesmaa, Minna; Schnabl, Katharina; Laitinen, Kirsi; Klén, Riku; Li, Yongguo; Balaz, Miroslav; Wolfrum, Christian; Steiger, Katja; Niemi, Tarja; Taittonen, Markku; U-Din, Mueez; Välikangas, Tommi; Elo, Laura L.; Eskola, Olli; Kirjavainen, Anna K.; Nummenmaa, Lauri; Virtanen, Kirsi A.; Klingenspor, Martin et al.. 2021. Nature metabolism. 3: 798-809

The FADS1 Genotype Modifes Metabolic Responses to the Linoleic Acid and Alpha-linolenic Acid Containing Plant Oils-Genotype Based Randomized Trial FADSDIET2

Lankinen, MA; de Mello, VD; Meuronen, T; Sallinen, T; Ågren, J; Virtanen, KA; Laakso, M; Pihlajamäki, J; Schwab, U. 2021. Molecular nutrition and food research. 65: 2001004

The Importance of Intestinal Length in Triglyceride Metabolism and in Predicting the Outcomes of Comorbidities in Laparoscopic Roux-en-Y Gastric Bypass-a Narrative Review

Käkelä, Pirjo; Rantanen, Tuomo; Virtanen, Kirsi A. 2021. Obesity surgery. 31: 3291-3295

Adenosine/A2B Receptor Signaling Ameliorates the Effects of Aging and Counteracts Obesity

Gnad, T; Navarro, G; Lahesmaa, M; Reverte-Salisa, L; Copperi, F; Cordomi, A; Naumann, J; Hochhäuser, A; Haufs-Brusberg, S; Wenzel, D; Suhr, F; Jespersen, NZ; Scheele, C; Tsvilovskyy, V; Brinkmann, C; Rittweger, J; Dani, C; Kranz, M; Deuther-Conrad, W; Eltzschig, HK; et al. [incl. Virtanen, KA]. 2020. Cell metabolism. 32: 56-70

Basal and cold-induced fatty acid uptake of human brown adipose tissue is impaired in obesity

Saari, TJ; Raiko, J; U-Din, M; Niemi, T; Taittonen, M; Laine, J; Savisto, N; Haaparanta-Solin, M; Nuutila, P; Virtanen, KA. 2020. Scientific reports. 10: 14373

Brain substrate metabolism and ß-cell function in humans: A positron emission tomography study

Rebelos, Eleni; Mari, Andrea; Bucci, Marco; Honka, Miikka-Juhani; Hannukainen, Jarna C; Virtanen, Kirsi A; Hirvonen, Jussi; Nummenmaa, Lauri; Heni, Martin; Iozzo, Patricia; Ferrannini, Ele; Nuutila, Pirjo. 2020. Endocrinology, diabetes & metabolism. 3: e00136

Predicting Skeletal Muscle and Whole-Body Insulin Sensitivity Using NMR-Metabolomic Profiling

Klén, Riku; Honka, Miikka-Juhani; Hannukainen, Jarna; Huovinen, Ville; Bucci, Marco; Latva-Rasku, Aino; Venäläinen, Mikko; Kalliokoski, Kari; Virtanen, Kirsi; Lautamäki, Riikka; Iozzo, Patricia; Elo, Laura; Nuutila, Pirjo. 2020. Journal of the Endocrine Society. 4: 1-18

Ruskean rasvakudoksen toiminta ja merkitys

Laurila, Sanna; Lahesmaa, Minna; Nuutila, Pirjo; Virtanen, Kirsi A. 2020. Duodecim. 136: 625-632

Short dietary intervention with olive oil increases brown adipose tissue activity in lean but not overweight subjects

Monfort-Pires, Milena; U-Din, Mueez; Nogueira, Guilherme A; de Almeida-Faria, Juliana; Sidarta-Oliveira, Davi; Sant'Ana, Marcella Ramos; de Lima-Júnior, José C; Cintra, Dennys E; de Souza, Heraldo Possolo; Ferreira, Sandra R G; Sapienza, Marcelo Tatit; Virtanen, Kirsi A; Velloso, Licio A. 2020. Journal of clinical endocrinology and metabolism. 2021; 106: 472-484

Activation of Human Brown Adipose Tissue (BAT): Focus on Nutrition and Eating

Virtanen, Kirsi A. Teoksessa: Pfeifer, Alexander; Klingenspor, Martin; Herzig, Stephan(toim.) , 2019. Brown Adipose Tissue. s. 349-357. Springer

Exercise training alters lipoprotein particles independent of brown adipose tissue metabolic activity

Motiani, P; Teuho, J; Saari, T; Virtanen, KA; Honkala, SM; Middelbeek, RJ; Goodyear, LJ; Eskola, O; Andersson, J; Loeyttyniemi, E; Hannukainen, JC; Nuutila, P. 2019. Obesity science & practice. 5: 258-272

Brown Adipose Tissue Energy Metabolism in Humans

Carpentier, Andre C; Blondin, Denis P; Virtanen, Kirsi A; Richard, Denis; Haman, Francois; Turcotte, Eric E. 2018. Frontiers in endocrinology. 9: 447

Insulin-stimulated glucose uptake in skeletal muscle, adipose tissue and liver : a positron emission tomography study

Honka, Miikka-Juhani; Latva-Rasku, Aino; Bucci, Marco; Virtanen, Kirsi A; Hannukainen, Jarna C; Kalliokoski, Kari K; Nuutila, Pirjo. 2018. European journal of endocrinology. 178: 523-531

Kylmäaltistus saa ruskean rasvan polttamaan kaloreita

Virtanen, Kirsi. 2018. DIABETES JA LÄÄKÄRI. 47: 24-25

Postprandial Oxidative Metabolism of Human Brown Fat Indicates Thermogenesis

U Din, Mueez; Saari, Teemu; Raiko, Juho; Kudomi, Nobu; Maurer, Stefanie F; Lahesmaa, Minna; Fromme, Tobias; Amri, Ez-Zoubir; Klingenspor, Martin; Solin, Olof; Nuutila, Pirjo; Virtanen, Kirsi A. 2018. Cell metabolism. 28: 207-216.e3

Small Intestinal Length Associates with Serum Triglycerides Before and After LRYGB

Käkelä, Pirjo; Männistö, Ville; Vaittinen, Maija; Venesmaa, Sari; Kärjä, Vesa; Virtanen, Kirsi; Paajanen, Hannu; Pihlajamäki, Jussi. 2018. Obesity surgery. 28: 3969-3975