MARKO PIETILä

Contact info

Research groups - UEF

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  North Savo Talent Hub

Publications

• Idehen, Esther E; Pietilä, Anna-Maija; Kangasniemi, Mari. 2020. Barriers and Facilitators to Cervical Screening among Migrant Women of African Origin: A Qualitative Study in Finland International journal of environmental research and public health 17 20: 7473. 2020
• Pietilä Marko, Halmekytö Maria. 2015. Erillisistä molekyylibiologian harjoitustyökursseista tutkimusprojektiksi. Yliopistopedagogiikka 22 1: 32-35. 2015
• Hyvönen Mervi T, Koponen Taina, Weisell Janne, Pietilä Marko, Khomutov Alex R, Vepsäläinen Jouko, Alhonen Leena, Keinänen Tuomo A. 2013. Spermidine promotes adipogenesis of 3T3-L1 cells by preventing interaction of ANP32 with HuR and PP2A. BIOCHEMICAL JOURNAL 453: 467-474. 2013
• Pietilä M, Dhungana H, Uimari A, Sironen R, Alhonen L. 2013. Systemic overexpression of antizyme 1 in mouse reduces ornithine decarboxylase activity without major changes in tissue polyamine homeostasis. TRANSGENIC RESEARCH [Epub ahead of print]: -. 2013
• Pietilä M, Ryhänen S, Mahonen A, Palvimo J. 2013. Terveyden biotieteiden opiskelijoiden työelämäorientaation rakentaminen: Kaarniemi H, Luotsausta ja luovintaa. Publications of the University of Eastern Finland. General Series 12. 63-70. 2013
• Cerrada-Gimenez M, Pietilä Marko, Loimas Suvikki, Pirinen Eija , Hyvönen Mervi T, Keinänen Tuomo A, Jänne Juhani, Alhonen Leena. 2011. Continuous oxidative stress due to activation of polyamine catabolism accelerates aging and protects against hepatotoxic insults TRANSGENIC RESEARCH 20: 387-396. 2011
• Pietilä M, Lampinen A, Pellinen R, Alhonen L. 2011. Inducible expression of antizyme 1 in prostate cancer cell lines after lentivirus mediated gene transfer AMINO ACIDS 2012 Feb;42(2-3): 559-64. 2011
• Ramot Y, Tiede S, Bíró T, Abu Bakar MH, Sugawara K, Philpott MP, Harrison W, Pietilä M, Paus R.. 2011. Spermidine promotes human hair growth and is a novel modulator of human epithelial stem cell functions PLOS ONE [ONLINE] 2011;6(7):e22564: --. 2011
• Fashe TM, Keinänen TA, Grigorenko NA, Khomutov AR, Jänne J, Alhonen L & Pietilä M. 2010. Cutaneous application of alpha-methylspermidine activates the growth of resting hair follicles in mice AMINO ACIDS 38: 583-590. 2010
• Pirinen E, Gylling H, Itkonen P, Yaluri N, Heikkinen S, Pietilä M, Kuulasmaa T, Tusa M, Cerrada-Gimenez M, Pihlajamäki J, Alhonen L, Jänne J, Miettinen TA & Laakso M. 2010. Activated polyamine catabolism leads to low cholesterol levels by enhancing bile acid synthesis. AMINO ACIDS 38: 549-560. 2010
• Ramot Y, Pietilä M, Giuliani G, Rinaldi F, Alhonen L & Paus R. 2010. Polyamines and hair: a couple in search of perfection. EXPERIMENTAL DERMATOLOGY 19 9: 784-790. 2010
• Vuohelainen S, Pirinen E, Cerrada-Gimenez M, Keinänen TA, Uimari A, Pietilä M, Khomutov AR, Jänne J & Alhonen L. 2010. Spermidine is indispensable in differentiation of 3T3-L1 fibroblasts to adipocytes. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE 14 6b: 1683-1692. 2010
• Weisell J, Hyvönen MT, Häkkinen MR, Grigorenko NA, Pietilä M, Lampinen A, Kochetkov SN, Alhonen L, Vepsäläinen J, Keinänen TA et al. 2010. Synthesis and Biological Characterization of Novel Charge-Deficient Spermine Analogues. JOURNAL OF MEDICINAL CHEMISTRY 53 15: 5738-5748. 2010
• Alhonen L, Uimari A, Pietilä M, Hyvönen MT, Pirinen E, Keinänen TA. 2009. Transgenic animals modelling polyamine metabolism-related diseases. ESSAYS IN BIOCHEMISTRY 46: 125-144. 2009
• Khomutov AR, Keinanen TA, Grigorenko NA, Hyvonen MT, Uimari A, Pietila M, Cerrada-Gimenez M, Simonian AR, Khomutov MA, Vepsalainen J, Alhonen L, Janne J. 2009. Methylated analogs of spermine and spermidine as tools to investigate cellular functions of polyamines and the enzymes of their metabolism. MOLEKULIARNAIA BIOLOGIIA [MOSKVA] 43 2: 274-285. 2009
• Pirinen E, Kuulasmaa T, Pietilä M, Heikkinen S, Tusa M, Itkonen P, Boman S, Skommer J, Virkamäki A, Hohtola E, Kettunen M, Fatrai S, Kansanen E, Koota S, Niiranen K, Parkkinen J, Levonen A-L, Ylä-Herttuala S, Hiltunen JK, Alhonen L, Smith U, Jänne J. 2007. Enhanced polyamine catabolism alters homeostatic control of white adipose tissue mass, energy expenditure, and glucose metabolism MOLECULAR AND CELLULAR BIOLOGY 27 13: 4953-4967. 2007
• Merentie M, Uimari A, Pietilä M, Sinervirta R, Keinänen TA, Vepsäläinen J, Khomutov A, Grigorenko N, Herzig K-H, Jänne J, Alhonen L. 2007. Oxidative stress and inflammation in the pathogenesis of activated polyamine catabolism-induced acute pancreatitis AMINO ACIDS 33 2: 323-330. 2007
• Jänne J, Alhonen L, Pietilä M, Keinänen TA, Suppola S, Pirinen E, Hyvönen MT, Järvinen A, Laakso M. 2006. Genetic engineering of polyamine catabolism in transgenic mice and rats: Wang J-Y, Casero RA Jr, Polyamine Cell Signaling. Physiology, Pharmacology, and Cancer Research.Humana Press. 465-477. 2006
• Jänne J, Alhonen L, Pietilä M, Keinänen TA, Uimari A, Hyvönen MT, Pirinen E. 2006. Genetic manipulation of polyamine catabolism in rodents. JOURNAL OF BIOCHEMISTRY 139 2: 155-160. 2006
• Niiranen K, Keinänen TA, Pirinen E, Heikkinen S, Tusa M, Fatrai S, Suppola S, Pietilä M, Uimari A, Laakso M, Alhonen L, Jänne J. 2006. Mice with targeted disruption of spermidine/spermine N1-acetyltransferese gene maintain nearly normal tissue polyamine homeostasis but show signs of insulin resistance upon aging JOURNAL OF CELLULAR AND MOLECULAR MEDICINE 10: 933-945. 2006
• Pietilä M. 2006. Polyamiinien merkitys keratinosyyttien erilaistumisessa. SOLUBIOLOGI 24 2: 23-27. 2006
• Jänne J, Alhonen L, Keinänen TA, Pietilä M, Uimari A, Pirinen E, Hyvönen MT, Järvinen A. 2005. Animal disease models generated by genetic engineering of polyamine metabolism. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE 9 4: 865-882. 2005
• Pietilä M, Pirinen E, Keskitalo S, Juutinen S, Pasonen-Seppänen S, Keinänen T, Alhonen L, Jänne J. 2005. Disturbed keratinocyte differentiation in transgenic mice and organotypic keratinocyte cultures as a result of spermidine/spermine N1-acetyltransferase overexpression. JOURNAL OF INVESTIGATIVE DERMATOLOGY 124 3: 596-601. 2005
• Jänne J, Alhonen L, Pietilä M, Keinänen TA. 2004. Genetic approaches to the cellular functions of polyamines in mammals. FEBS JOURNAL 271 2: 877-894. 2004
• Alhonen L, Räsänen T-L, Sinervirta R, Parkkinen JJ, Korhonen V-P, Pietilä M, Jänne J. 2002. Polyamines are required for the initiation of rat liver regeneration. BIOCHEMICAL JOURNAL 362: 149-153. 2002
• Niiranen K, Pietilä M, Pirttilä TJ, Järvinen A, Halmekytö M, Korhonen V-P, Keinänen TA, Alhonen L, Jänne J. 2002. Targeted disruption of spermidine/spermine N1-acetyltransferase gene in mouse embryonic stem cells. JOURNAL OF BIOLOGICAL CHEMISTRY 277 28: 25323-25328. 2002
• Korhonen V-P, Niiranen K, Halmekytö M, Pietilä M, Diegelman P, Parkkinen JJ, Eloranta T, Porter CW, Alhonen L, Jänne J. 2001. Spermine deficiency resulting from targeted disruption of the spermine synthase gene in embryonic stem cells leads to enhanced sensitivity to antiproliferative drugs. MOLECULAR PHARMACOLOGY 59 2: 231-238. 2001
• Pietilä M, Parkkinen JJ, Alhonen L, Jänne J. 2001. Relation of skin polyamines to the hairless phenotype in transgenic mice overexpressing spermidine/spermine N1-acetyltransferase JOURNAL OF INVESTIGATIVE DERMATOLOGY 116 5: 801-805. 2001
• Pietilä M. 2001. Activation of Polyamine Catabolism in Transgenic Mice. Kuopion yliopiston julkaisuja C. Luonnontieteet ja ympäristötieteet. 2001
• Alhonen L, Pietilä M, Halmekytö M, Kramer DL, Jänne J, Porter CW. 1999. Transgenic mice with activated polyamine catabolism due to overexpression of spermidine/spermine N1-acetyltransferase show enhanced sensitivity to the polyamine analog, N1, N11-diethylnorspermine. MOLECULAR PHARMACOLOGY 54: 693-698. 1999
• Heikkinen S, Pietilä M, Halmekytö M, Suppola S, Pirinen E, Deeb SS, Jänne J, Laakso M. 1999. Hexokinase II-deficient mice: prenatal death of homozygotes without disturbances in glucose tolerance in heterozygotes. JOURNAL OF BIOLOGICAL CHEMISTRY 274: 22517-22523. 1999
• Jänne J, Alhonen L, Halmekytö M, Pietilä M. 1999. Genetic engineering of polyamine metabolism: consequences of the activation of polyamine biosynthesis or catabolism in transgenic rodents: Bardócz S, White A, Polyamines in Health and Nutrition.Kluwer. 87-98. 1999
• Suppola S, Pietilä M, Parkkinen JJ, Korhonen V-P, Alhonen L, Halmekytö M, Porter CW, Jänne J. 1999. Overexpression of spermidine/spermine N1-acetyltransferase under the control of mouse metallothionein I promoter in transgenic mice: evidence for a striking post-transcriptional regulation of transgene expression by a poly. BIOCHEMICAL JOURNAL 338: 311-316. 1999