Early Stage Researcher
I am an early stage researcher in AIVI/Lehtonen group. I'm currently working with hiPSC-derived midbrain organoids and studying their utility as in vitro models of Parkinson's disease. The incidence of neurodegenerative diseases is expected to increase as the population ages, which in turn creates an increasing need for more effective treatments. To accelerate drug discovery efforts, improved in vitro models are needed. Brain organoids could provide a human-derived, physiologically relevant, high-throughput-compatible alternative to animal models and 2D cell culture.
Research groups and research projects
Research groups - UEF
Aaltonen, Niina; Singha, Prosanta; Jakupovic, Hermina; Wirth, Thomas; Samaranayake, Haritha; Pasonen-Seppänen, Sanna; Rilla, Kirsi; Varjosalo, Markku; Edgington-Mitchell, Laura; Kasperkiewicz, Paulina; Drag, Marcin; Kälvälä, Sara; Moisio, Eemeli; Savinainen, Juha; Laitinen, Jarmo. 2020. High-Resolution Confocal Fluorescence Imaging of Serine Hydrolase Activity in Cryosections - Application to Glioma Brain Unveils Activity Hotspots Originating from Tumor-Associated Neutrophils Biological procedures online 22: 6. 2020