Sirtuin Research Group- UEF Pharmacy

Sirtuin Research Group at School of Pharmacy develops novel modulators involved in histone acetylation. We have hundreds of in-house epigenetic regulators. We explore the regulation of sirtuins and BRD bromodomains in cancer.

Tumor-stroma interaction - Pasonen-Seppänen group

01.09.2019 -
Tumor microenvironment (TME) has an active contribution to tumor development and cancer progression. This extremely complex system is composed of multiple cell types, such as fibroblasts and infiltrating immune cells, and structural extracellular matrix (ECM), which is mainly composed of hyaluron...

Molecular Modeling and Drug Design Research Group

Our molecular modeling and computer-aided drug design (CADD) group at School of Pharmacy in Kuopio applies various computational chemistry methods to speed up identification of new drug candidates, and to improve their properties. Our group utilizes both structure-based and ligand-based methods.