Einar Aavik
Vieraileva tutkija
A.I. Virtanen -instituutti, Terveystieteiden tiedekunta
einari.aavik@uef.fi
Julkaisut
18 kappaletta-
ApoA-I Nanotherapy Rescues Postischemic Vascular Maladaptation by Modulating Endothelial Cell and Macrophage Phenotypes in Type 2 Diabetic Mice
Babu, Mohan; Devi, Durga; Mäkinen, Petri; Örd, Tiit; Aavik, Einari; Kaikkonen, Minna; Ylä-Herttuala, Seppo. 2023. Arteriosclerosis, thrombosis, and vascular biology. 43: e46–e61 -
Dissecting the polygenic basis of atherosclerosis via disease-associated cell state signatures
Örd, Tiit; Lönnberg, Tapio; Nurminen, Valtteri; Ravindran, Aarthi; Niskanen, Henri; Kiema, Miika; Õunap, Kadri; Maria, Maleeha; Moreau, Pierre R; Mishra, Pashupati P; Palani, Senthil; Virta, Jenni; Liljenbäck, Heidi; Aavik, Einari; Roivainen, Anne; Ylä-Herttuala, Seppo; Laakkonen, Johanna P; Lehtimäki, Terho; Kaikkonen, Minna U. 2023. American journal of human genetics. 110: 722-740 -
ErbB signalling is a potential therapeutic target for vascular lesions with fibrous component
Jauhiainen, Suvi; Ilmonen, Henna; Vuola, Pia; Rasinkangas, Heta; Pulkkinen, Heidi H; Keränen, Sara; Kiema, Miika; Liikkanen, Jade J; Laham Karam, Nihay; Laidinen, Svetlana; Beter, Mustafa; Aavik, Einari; Lappalainen, Kimmo; Lohi, Jouko; Aronniemi, Johanna; Örd, Tiit; Kaikkonen, Minna U; Salminen, Päivi; Tukiainen, Erkki; Ylä-Herttuala, Seppo; Laakkonen, Johanna P. 2023. eLife. 12: -
Hypoxic regulation of hypoxia inducible factor 1 alpha via antisense transcription
Downes, Nicholas; Niskanen, Henri; Tomas-Bosch, Vanesa; Taipale, Mari; Godiwala, Mehvash; Väänänen, Mari-Anna; Turunen, Tiia A; Aavik, Einari; Laham-Karam, Nihay; Ylä-Herttuala, Seppo; Kaikkonen, Minna U. 2023. Journal of biological chemistry. 299: -
Epigenetic Regulation of Vascular Smooth Muscle Cell Phenotype Switching in Atherosclerotic Artery Remodeling: A Mini-Review
Zurek, Michelle; Aavik, Einari; Mallick, Rahul; Ylä-Herttuala, Seppo. 2021. Frontiers in genetics. 12: 719456 -
Single-Cell Epigenomics and Functional Fine-Mapping of Atherosclerosis GWAS Loci
Örd, Tiit; Õunap, Kadri; Stolze, Lindsey; Aherrahrou, Rédouane; Nurminen, Valtteri; Selvarajan, Ilakya; Toropainen, Anu; Lönnberg, Tapio; Aavik, Einari; Yla-Herttuala, Seppo; Civelek, Mete; Romanoski, Casey E; Kaikkonen, Minna U. 2021. Circulation research. 129: 240-258 -
Microanatomy of the Human Atherosclerotic Plaque by Single-Cell Transcriptomics
Depuydt, Marie Ac; Prange, Koen Hm; Slenders, Lotte; Örd, Tiit; Elbersen, Danny; Boltjes, Arjan; de Jager, Saskia Ca; Asselbergs, Folkert W; de Borst, Gert J; Aavik, Einari; Lönnberg, Tapio; Lutgens, Esther; Glass, Christopher K; den Ruijter, Hester M; Kaikkonen, Minna U; Bot, Ilze; Slütter, Bram; van der Laan, Sander W; Ylä-Herttuala, Seppo; Mokry, Michal; et al. 2020. Circulation research. 127: 1437-1455 -
DNA methylation processes in atheosclerotic plaque
Aavik, Einari; Babu, Mohan; Ylä-Herttuala, Seppo. 2019. Atherosclerosis. 281: 168-179 -
Smoking is Associated to DNA Methylation in Atherosclerotic Carotid Lesions
Siemelink, Marten A; van der Laan, Sander W; Haitjema, Saskia; van Koeverden, Ian D; Schaap, Jacco; Wesseling, Marian; de Jager, Saskia C A; Mokry, Michal; van Iterson, Maarten; Dekkers, Koen F; Luijk, Rene; Asl, Hassan Foroughi; Michoel, Tom; Björkegren, Johan L M; Aavik, Einari; Ylä-Herttuala, Seppo; de Borst, Gert J; Asselbergs, Folkert W; el Azzouzi, Hamid; den Ruijter, Hester M; et al.. 2018. Circulation. Genomic and precision medicine. 11: e002030 -
Therapeutic effects of rosuvastatin in hypercholesterolemic prediabetic mice in the absence of low density lipoprotein receptor
Gurzeler, Erika; Aavik, Einari; Laine, Anssi; Valkama, Teemu; Niskanen, Henri; Huusko, Jenni; Kaikkonen, Minna U; Ylä-Herttuala, Seppo. 2018. Biochimica et biophysica acta: general subjects. 2019; 1863: 481-490