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Eino Solje

Eino Solje

Tutkimusjohtaja

Apulaisprofessori

LT, apulaisprofessori (tenure track), neurologian erikoislääkäri

eino.solje@uef.fi | 050 465 6866

Tiedot Julkaisut

Kliinisen tutkimuksen apulaipsrofessori ja Aivotutkimusyksikön johtaja

Tutkimusjohtaja, Frontotemporal Lobar Degeneration and Early Onset Dementia -tutkimusryhmä
Partneri kansallisessa FinFTD-tutkimuskonsortiossa

Tutkimusryhmät

Aivotutkimusyksikkö 01.01.2022 -
Frontotemporal Lobar Degeneration and Early Onset… 01.01.2022 -
Otsalohkodementiatutkimuksen verkosto (FinFTD) 01.05.2016 -

Projektit

UEF Aivotutkimusyksikkö 2.0 01.03.2023 - 28.02.2025
Varjoja paratiisissa? Muistisairaan ihmisen oikeuksien toteutuminen hyvinvointivaltiossa 01.01.2022 - 31.05.2032

- LT Kasper Katisko
- LL Sami Heikkinen
- LK Marjut Haapanen
- LK Titta Korhonen
- LK Annu Toivanen
- FM Tomi Hietanen
- OtM Kaisa Näkki
- LK Helmi Soppela
- LL Ave Kivisild
- LK Kalle Aho
- LK Kaarlo Ylimäki
- LK Meri Juslin
- FM Hille Halonen
- FM Elena Ppali
- FM Alex Berg
- LK Laura Leppänen
- LK Iina Lempiäinen
- LK Susanna SIpilä
- LK Adolfina Lehtonen
- LK Kenske Kränä
- LK Mika Kinnunen
- LK Matti Tyrväinen
- HLK Lauriina Soiniemi
- Johtaja, Aivotutkimusyksikkö
- Apulaisprofessori, Frontotemporal Lobar Degeneration and Early Onset Dementia -rtutkimusryhmä
- Neurologi, Kuopion yliopistollinen sairaala, Neurokeskus
- Dosentti
- Neurologian erikoislääkäri
- Lääketieteen tohtori

Avainsanat

aivotutkimus biomarkkerit dementia käytösoireet muistisairaudet muistisairaus neurodegeneraatio neurologia otsalohkodementia

Julkaisut

57/57 kappaletta

Anti-GluA3 autoantibodies define a new sub-population of frontotemporal lobar degeneration patients with distinct neuropathological features
Italia, Maria; Salvadè, Michela; La Greca, Filippo; Zianni, Elisa; Pelucchi, Silvia; Spinola, Alessio; Ferrari, Elena; Archetti, Silvana; Alberici, Antonella; Benussi, Alberto; Solje, Eino; Haapasalo, Annakaisa; Hoffmann, Dorit; Katisko, Kasper; Krüger, Johanna; Facchinetti, Roberta; Scuderi, Caterina; Padovani, Alessandro; DiLuca, Monica; Scheggia, Diego; Borroni, Barbara; Gardoni, Fabrizio. 2024. Brain behavior and immunity. 118: 380-397
Evaluating the need for legal guardianship in people with dementia: gaining insight into professionals’ assessment criteria
Näkki, Kaisa; Mäki-Petäjä-Leinonen, Anna; Ervasti, Kaijus; Solje, Eino. 2024. International journal of law, policy and the family. 38:
‘Something is dropped out of the journey of life’: perceived spaces of opportunity among people with dementia
Gadd, Katri; Mauranen, Katariina; Issakainen, Mervi; Ervasti, Kaijus; Mäki-Petäjä-Leinonen, Anna; Solje, Eino. 2024. GeoJournal. 89:
Amyotrophic Lateral Sclerosis in Southwestern and Eastern Finland
Hanhisuanto, Mirka; Solje, Eino; Jokela, Manu; Sipilä, Jussi OT. 2023. Neuroepidemiology. 57: 238-245
Incidence of Syndromes Associated With Frontotemporal Lobar Degeneration in 9 European Countries
Logroscino, Giancarlo; Piccininni, Marco; Graff, Caroline; Hardiman, Orla; Ludolph, Albert C; Moreno, Fermin; Otto, Markus; Remes, Anne M; Rowe, James B; Seelaar, Harro; Solje, Eino; Stefanova, Elka; Traykov, Latchezar; Jelic, Vesna; Rydell, Melissa Taheri; Pender, Niall; Anderl-Straub, Sarah; Barandiaran, Myriam; Gabilondo, Alazne; Kruger, Johanna; Murley, Alexander G; Rittman, Timothy; van der Ende, Emma L; van Swieten, John C; Hartikainen, Paeivi; Stojmenovic, Gorana Mandic; Mehrabian, Shima;. 2023. JAMA neurology. 80: 279-286
Psychopharmacological Medication Use in Frontotemporal Dementia at the Time of Diagnosis: Comparison with Alzheimer’s Disease
Katisko, Kasper; Krüger, Johanna; Soppela, Helmi; Hartikainen, Päivi; Haapasalo, Annakaisa; Remes, Anne M.; Solje, Eino. 2023. Journal of Alzheimer's disease. 95: 677-685
Salivary Metabolomics in the Diagnosis and Monitoring of Neurodegenerative Dementia
Hyvärinen, Eelis; Solje, Eino; Vepsäläinen, Jouko; Kullaa, Arja; Tynkkynen, Tuulia. 2023. Metabolites. 13:
Serum Cathepsin S Levels Do Not Show Alterations in Different Clinical, Neuropathological, or Genetic Subtypes of Frontotemporal Dementia Patients nor in Comparison to Healthy Control Individuals
Heikkinen, Sami; Huber, Nadine; Katisko, Kasper; Kokkola, Tarja; Hartikainen, Päivi; Krüger, Johanna; Leinonen, Ville; Korhonen, Ville E; Herukka, Sanna-Kaisa; Remes, Anne M; Borroni, Barbara; Alberici, Antonella; Libri, Ilenia; Solje, Eino; Haapasalo, Annakaisa. 2023. Journal of Alzheimer's disease. 93: 395-401
Syljen metabolomiikan sovellutuksia suulääketieteellisessä tutkimuksessa
Hyvärinen, Eelis; Solje, Eino; Vepsäläinen, Jouko; Kullaa, Arja; Tynkkynen, Tuulia. 2023. Suomen hammaslääkärilehti. 30: 27
Traumatic Brain Injury Associates with an Earlier Onset in Sporadic Frontotemporal Dementia
Soppela, Helmi; Krüger, Johanna; Hartikainen, Päivi; Koivisto, Anne; Haapasalo, Annakaisa; Borroni, Barbara; Remes, Anne M.; Katisko, Kasper; Solje, Eino. 2023. Journal of Alzheimer's disease. 91: 225-232
Brainstem atrophy is linked to extrapyramidal symptoms in frontotemporal dementia
Heikkinen, Sami; Cajanus, Antti; Katisko, Kasper; Hartikainen, Päivi; Vanninen, Ritva; Haapasalo, Annakaisa; Krüger, Johanna; Remes, Anne M; Solje, Eino. 2022. Journal of neurology. 269: 4488-4497
Cognitive impairment is not uncommon in patients with biallelic RFC1 AAGGG repeat expansion, but the expansion is rare in patients with cognitive disease
Korpioja, Anita; Krüger, Johanna; Hurme-Niiranen, Anri; Solje, Eino; Katisko, Kasper; Lipponen, Joonas; Lehtilahti, Maria; Remes, Anne M.; Majamaa, Kari; Kytövuori, Laura. 2022. Parkinsonism and related disorders. 103: 98-101
Increasing Brain Gamma Activity Improves Episodic Memory and Restores Cholinergic Dysfunction in Alzheimer's Disease
Benussi, Alberto; Cantoni, Valentina; Grassi, Mario; Brechet, Lucie; Michel, Christoph M.; Datta, Abhishek; Thomas, Chris; Gazzina, Stefano; Cotelli, Maria Sofia; Bianchi, Marta; Premi, Enrico; Gadola, Yasmine; Cotelli, Maria; Pengo, Marta; Perrone, Federica; Scolaro, Maria; Archetti, Silvana; Solje, Eino; Padovani, Alessandro; Pascual‐Leone, Alvaro; Borroni, Barbara. 2022. Annals of neurology. 92: 322-334
Lääkärinlausunto ratkaisijan pöydällä
Näkki, Kaisa; Mäki-Petäjä-Leinonen, Anna; Ervasti, Kaijus; Koivisto, Anne; Krüger, Johanna; Solje, Eino. 2022. Yleislääkäri. 37: 26-29
Modifiable potential risk factors in familial and sporadic frontotemporal dementia
Soppela, Helmi; Katisko, Kasper; Gadola, Yasmine; Krüger, Johanna; Hartikainen, Päivi; Alberici Antonella; Benussi, Alberto; Koivisto,Anne; Haapasalo, Annakaisa; Remes, Anne M; Borroni, Barbara; Solje, Eino. 2022. Annals of clinical and translational neurology. 9: 1195-1205
Serum total TDP-43 levels are decreased in frontotemporal dementia patients with C9orf72 repeat expansion or concomitant motoneuron disease phenotype
Katisko, Kasper; Huber, Nadine; Kokkola, Tarja; Hartikainen, Päivi; Krüger, Johanna; Heikkinen, Anna-Leena; Paananen, Veera; Leinonen, Ville; Korhonen, Ville E.; Helisalmi, Seppo; Herukka, Sanna-Kaisa; Cantoni, Valentina; Gadola, Yasmine; Archetti, Silvana; Remes, Anne M.; Haapasalo, Annakaisa; Borroni, Barbara; Solje, Eino. 2022. Alzheimer's research and therapy. 14: . 151
A Novel Genetic Marker for the C9orf72 Repeat Expansion in the Finnish Population
Rostalski, H; Korhonen, V; Kuulasmaa, T; Solje, E; Krüger, J; Gen, F; Kaivola, K; Eide, PK; Lambert, JC; Julkunen, V; Tienari, PJ; Remes, AM; Leinonen, V; Hiltunen, M; Haapasalo, A. 2021. Journal of Alzheimer's disease. 83: 1325-1332
C9orf72 hexanucleotide repeat expansion leads to altered neuronal and dendritic spine morphology and synaptic dysfunction
Huber, Nadine; Hoffmann, Dorit; Giniatullina, Raisa; Rostalski, Hannah; Leskelä, Stina; Takalo, Mari; Natunen, Teemu; Solje, Eino; Remes, Anne M.; Giniatullin, Rashid; Hiltunen, Mikko; Haapasalo, Annakaisa. 2021. Neurobiology of disease. 2022; 162: 105584
Deficient neurotransmitter systems and synaptic function in frontotemporal lobar degeneration-Insights into disease mechanisms and current therapeutic approaches
Huber, Nadine; Korhonen, Sonja; Hoffmann, Dorit; Leskelä, Stina; Rostalski, Hannah; Remes, Anne M.; Honkakoski, Paavo; Solje, Eino; Haapasalo, Annakaisa. 2021. Molecular psychiatry. Published online: 19 November 2021: 1 - 10
Experimental Disease-Modifying Agents for Frontotemporal Lobar Degeneration
Giunta, Marcello; Solje, Eino; Gardoni, Fabrizio; Borroni, Barbara; Benussi, Alberto. 2021. Journal of experimental pharmacology. 13: 359-376
FRONTotemporal dementia Incidence European Research Study - FRONTIERS: Rationale and design
Borroni, Barbara; Graff, Caroline; Hardiman, Orla; Ludolph, Albert C; Moreno, Fermin; Otto, Markus; Piccininni, Marco; Remes, Anne M; Rowe, James B; Seelaar, Harro; Stefanova, Elka; Traykov, Latchezar; Logroscino, Giancarlo; Alberici, Antonella; Anderl-Straub, Sarah; Barandiaran, Myriam; Belezhanska, Diyana; Benussi, Alberto; Bianchetti, Angelo; Capozzo, Rosa; FRONTIERS [incl. Solje, Eino]. 2021. Alzheimer's & dementia. 2022; 18: 498-506
FTLD Patient-Derived Fibroblasts Show Defective Mitochondrial Function and Accumulation of p62
Leskelä, S; Hoffmann, D; Rostalski, H; Huber, N; Wittrahm, R; Hartikainen, P; Korhonen, V; Leinonen, V; Hiltunen, M; Solje, E; Remes, AM; Haapasalo, A. 2021. Molecular neurobiology. 58: 5438-5458
GFAP as a biomarker in frontotemporal dementia and primary psychiatric disorders: diagnostic and prognostic performance
Katisko, Kasper; Cajanus, Antti; Huber, Nadine; Jääskeläinen, Olli; Kokkola, Tarja; Kärkkäinen, Virve; Rostalski, Hannah; Hartikainen, Paivi; Koivisto, Anne M; Hannonen, Sanna; Lehtola, Juha-Matti; Korhonen, Ville E; Helisalmi, Seppo; Koivumaa-Honkanen, Heli; Herukka, Sanna-Kaisa; Remes, Anne M; Solje, Eino; Haapasalo, Annakaisa. 2021. Journal of neurology neurosurgery and psychiatry. 92: 1305-1312
Otsa-ohimolohkorappeumat
Solje, Eino; Krüger, Johanna; Suhonen, Noora; Remes, Anne M. Teoksessa: Juva, Kati; Hublin, Christer; Kalska, Hely; Korkeila, Jyrki; Sainio, Markku; Tani, Pekka; Vataja, Risto(toim.) , 2021. Kliininen neuropsykiatria (2. uudistettu painos). s. 262-273. Duodecim
Otsa-ohimolohkorappeumat - miten tunnistan ja hoidan?
Krüger, Johanna; Katisko, Kasper; Suhonen, Noora-Maria; Haapasalo, Annakaisa; Remes, Anne M; Solje, Eino. 2021. Duodecim. 137: 2307-2316
Primary progressive aphasias associated with C9orf72 expansions: Another side of the story
Saracino, Dario; Géraudie, Amandine; Remes, Anne M.; Ferrieux, Sophie; Noguès-Lassiaille, Marie; Bottani, Simona; Cipriano, Lorenzo; Houot, Marion; Funkiewiez, Aurélie; Camuzat, Agnès; Rinaldi, Daisy; Teichmann, Marc; Pariente, Jérémie; Couratier, Philippe; Boutoleau-Bretonnière, Claire; Auriacombe, Sophie; Etcharry-Bouyx, Frédérique; Levy, Richard; Migliaccio, Raffaella; Solje, Eino et al. 2021. Cortex. 145: 145-159
Serum GFAP and NfL levels in benign relapsing-remitting multiple sclerosis
Niiranen, Marja; Kontkanen, Aleksi; Jääskeläinen, Olli; Tertsunen, Hanna-Mari; Selander, Tuomas; Hartikainen, Päivi; Huber, Nadine; Solje, Eino; Haapasalo, Annakaisa; Kokkola, Tarja; Lohioja, Tarja; Herukka, Sanna-Kaisa; Simula, Sakari; Remes, Anne M.. 2021. Multiple sclerosis and related disorders. 56: 103280
State-of-the-Art Methods and Emerging Fluid Biomarkers in the Diagnostics of Dementia-A Short Review and Diagnostic Algorithm
Solje, Eino; Benussi, Alberto; Buratti, Emanuele; Remes, Anne M; Haapasalo, Annakaisa; Borroni, Barbara. 2021. Diagnostics. 11: 788
Suuntana muistisairauden yksilöllinen varhaisdiagnostiikka ja hoito
Solje, Eino; Remes, Anne M; Krüger, Johanna. 2021. Duodecim. 137: 2223-2225
BV-2 Microglial Cells Overexpressing C9orf72 Hexanucleotide Repeat Expansion Produce DPR Proteins and Show Normal Functionality but No RNA Foci
Rostalski, Hannah; Hietanen, Tomi; Leskelä, Stina; Behánová, Andrea; Abdollahzadeh, Ali; Wittrahm, Rebekka; Mäkinen, Petra; Huber, Nadine; Hoffmann, Dorit; Solje, Eino; Remes, Anne M; Natunen, Teemu; Takalo, Mari; Tohka, Jussi; Hiltunen, Mikko; Haapasalo, Annakaisa. 2020. Frontiers in neurology. 11: 550140
C9orf72 Repeat Expansion Does Not Affect the Phenotype in Primary Progressive Aphasia
Haapanen, Marjut; Katisko, Kasper; Hänninen, Tuomo; Krüger, Johanna; Hartikainen, Päivi; Haapasalo, Annakaisa; Remes, Anne M; Solje, Eino. 2020. Journal of Alzheimer's disease. 78: 919-925
Comparison of Prodromal Symptoms of Patients with Behavioral Variant Frontotemporal Dementia and Alzheimer Disease
Korhonen, Titta; Katisko, Kasper; Cajanus, Antti; Hartikainen, Päivi; Koivisto, Anne M; Haapasalo, Annakaisa; Remes, Anne M; Solje, Eino. 2020. Dementia and geriatric cognitive disorders. 49: 98-106
Frontotemporal dementia: a conference report from the 2nd FinFTD Symposium
Hoffmann, Dorit; Huber, Nadine; Leskelä, Stina; Rostalski, Hannah; Solje, Eino; Remes, Anne M; Haapasalo, Annakaisa. 2020. Neurodegenerative disease management. 10: 1758-2024
Huippuasiantuntijaksi ei kehity harjoittelemalla yksinäisyydessä
Solje, Eino. 2020. Duodecim. 136: 1505-1507
Serum neurofilament light chain in FTLD: association with C9orf72, clinical phenotype, and prognosis
Cajanus, Antti; Katisko, Kasper; Kontkanen, Aleksi; Jääskeläinen, Olli; Hartikainen, Päivi; Haapasalo, Annakaisa; Herukka, Sanna-Kaisa; Vanninen, Ritva; Solje, Eino; Hall, Anette; Remes, Anne. 2020. Annals of clinical and translational neurology. 7: 903-910
The ethical implications of genetic testing in neurodegenerative diseases: A systematic review
Nurmi, Sanna-Maria; Halkoaho, Arja; Moilanen, Jukka; Remes, Anne M; Solje, Eino. 2020. Scandinavian journal of caring sciences. 2021; 35: 1057-1074
Astrocytes and Microglia as Potential Contributors to the Pathogenesis of C9orf72 Repeat Expansion-Associated FTLD and ALS
Rostalski, Hannah; Leskelä, Stina; Huber, Nadine; Katisko, Kasper; Cajanus, Antti; Solje, Eino; Marttinen, Mikael; Natunen, Teemu; Remes, Anne M; Hiltunen, Mikko; Haapasalo, Annakaisa. 2019. Frontiers in neuroscience. 13: 486
Low Serum High-Density Lipoprotein Cholesterol Levels Associate with the C9orf72 Repeat Expansion in Frontotemporal Lobar Degeneration Patients
Jääskeläinen, O; Solje, E; Hall, A; Katisko, K; Korhonen, V; Tiainen, M; Kangas, AJ; Helisalmi, S; Pikkarainen, M; Koivisto, A; Hartikainen, P; Hiltunen, M; Ala-Korpela, M; Soininen, H; Soininen, P; Haapasalo, A; Remes, AM; Herukka, SK. 2019. Journal of Alzheimer's disease. 72: 127-137
Mutation Analysis of the Genes Linked to Early Onset Alzheimer's Disease and Frontotemporal Lobar Degeneration
Luukkainen, L; Helisalmi, S; Kytövuori, L; Ahmasalo, R; Solje, E; Haapasalo, A; Hiltunen, M; Remes, AM; Krüger, J. 2019. Journal of Alzheimer's disease. 69: 775-782
Neurologeilta hattutemppu - erikoislääkärikoulutus auditoitiin jo kolmannen kerran
Solje, Eino; Valkonen, Kati. 2019. Lääkärilehti. 74: 2808-2812
Prodromal and Early bvFTD: Evaluating Clinical Features and Current Biomarkers
Katisko, Kasper; Cajanus, Antti; Korhonen, Titta; Remes, Anne M; Haapasalo, Annakaisa; Solje, Eino. 2019. Frontiers in neuroscience. 13: 658
The Association Between Distinct Frontal Brain Volumes and Behavioral Symptoms in Mild Cognitive Impairment, Alzheimer's Disease, and Frontotemporal Dementia
Cajanus, A; Solje, E; Koikkalainen, J; Lötjönen, J; Suhonen, NM; Hallikainen, I; Vanninen, R; Hartikainen, P; de Marco, M; Venneri, A; Soininen, H; Remes, AM; Hall, A. 2019. Frontiers in neurology. 10: 1059
Automatic MRI Quantifying Methods in Behavioral-Variant Frontotemporal Dementia Diagnosis
Cajanus, A; Hall, A; Koikkalainen, J; Solje, E; Tolonen, A; Urhemaa, T; Liu, Y; Haanpää, RM; Hartikainen, P; Helisalmi, S; Korhonen, V; Rueckert, D; Hasselbalch, S; Waldemar, G; Mecocci, P; Vanninen, R; van Gils, M; Soininen, H; Lötjönen, J; Remes, AM. 2018. Dementia and geriatric cognitive disorders extra. 8: 51-59
Low Prevalence of Cancer in Patients with Frontotemporal Lobar Degeneration
Katisko, Kasper; Haapasalo, Annakaisa; Koivisto, Anne; Kruger, Johanna; Hartikainen, Päivi; Korhonen, Ville; Helisalmi, Seppo; Herukka, Sanna-Kaisa; Remes, Anne M; Solje, Eino. 2018. Journal of Alzheimer's disease. 62: 789-794
Otsalohkodementia - neurologian ja psykiatrian rajapinnalla
Solje, Eino; Remes, Anne M. 2018. Lääkärilehti. 73: 9
Otsalohkodementia - salakavala muistisairaus
Remes, Anne M; Haanpää, Ramona M; Suhonen, Noora-Maria; Junttila, Anna; Solje, Eino. 2018. Lääkärilehti. 73: 37-41
Prevalence of immunological diseases in a Finnish frontotemporal lobar degeneration cohort with the C9orf72 repeat expansion carriers and non-carriers
Katisko, K; Solje, E; Koivisto, AM; Krüger, J; Kinnunen, T; Hartikainen, P; Helisalmi, S; Korhonen, V; Herukka, S-K; Haapasalo, A; Remes, AM. 2018. Journal of neuroimmunology. 321: 29-35
Subtle Cognitive Impairment and Alzheimer's Disease-Type Pathological Changes in Cerebrospinal Fluid are Common Among Neurologically Healthy Subject
Haapalinna, F; Kokki, M; Jääskeläinen, O; Hallikainen, M; Helisalmi, S; Koivisto, A; Kokki, H; Paajanen, T; Penttinen, J; Pikkarainen, M; Rautiainen, M; Soininen, H; Solje, E; Remes, AM; Herukka, SK. 2018. Journal of Alzheimer's disease. 62: 165-174
The association between frontotemporal lobar degeneration and bullous pemphigoid
Katisko, Kasper; Kokkonen, Nina; Krüger, Johanna; Hartikainen, Päivi; Koivisto, Anne; Helisalmi, Seppo; Korhonen, Ville; Kokki, Merja; Tuusa, Jussi; Herukka, Sanna-Kaisa; Solje, Eino; Haapasalo, Annakaisa; Tasanen, Kaisa; Remes, Anne. 2018. Journal of Alzheimer's disease. 66: 743-750
Frontotemporal dementia as a comorbidity to idiopathic normal pressure hydrocephalus (iNPH): a short review of literature and an unusual case
Korhonen VE, Solje E, Suhonen NM, Rauramaa T, Vanninen R, Remes AM, Leinonen V. 2017. Fluids and barriers of the cns. 14: 10
Low Cerebrospinal Fluid Amyloid-Beta Concentration Is Associated with Poorer Delayed Memory Recall in Women
Haapalinna F, Paajanen T, Penttinen J, Kokki H, Kokki M, Koivisto AM, Hartikainen P, Solje E, Hänninen T, Remes AM, Herukka SK. 2016. Dementia and geriatric cognitive disorders extra. 6: 303-312
The C9ORF72 expansion sizes in patients with psychosis: a population-based study on the Northern Finland Birth Cohort 1966
Solje Eino, Miettunen Jouko, Marttila Riikka, Helisalmi Seppo, Laitinen Marjo, Koivumaa-Honkanen Heli, Isohanni Matti, Hiltunen Mikko, Jääskeläinen Erika, Remes Anne M. 2016. Psychiatric genetics. 26: 92-94
The Spectrum of the Phenotypes in the C9ORF72 Expansion Carriers: Insights at the Interface between Neurology and Psychiatry
Solje Eino. 2016. Publications of the University of Eastern Finland. Dissertations in Health Sciences
The role of the FTD-ALS associated C9orf72 expansion in suicide victims
Solje Eino, Riipinen Pirkko, Helisalmi Seppo, Särkioja Terttu, Laitinen Marjo, Hiltunen Mikko, Hakko Helinä, Remes Anne M. 2016. Amyotrophic lateral sclerosis & frontotemporal degeneration. 17: 589-592
Relationship between ubiquilin-1 and BACE1 in human Alzheimer's disease and APdE9 transgenic mouse brain and cell-based models
Natunen Teemu, Takalo Mari, Kemppainen Ssusanna, Leskelä Stina, Marttinen Mikael, Kurkinen Kaisa MA, Pursiheimo Juha-Pekka, Sarajärvi Timo, Viswanathan Jayashree, Gabbouj Sami, Solje Eino, Tahvanainen Eveliina, Pirttimäki Tiina, Kurki Mitja, Paananen Jussi, Rauramaa Tuomas, Miettinen Pasi, Mäkinen Petra, Leinonen Ville, Soininen Hilkka et al. 2015. Neurobiology of disease. 2016; 85: 187-205
The phenotype of the C90RF72 Expansion carriers according to revised crieria for bvFTD
Solje Eino, Aaltokallio Heidi, Koivumaa-Honkanen Heli, Suhonen Noora M, Moilanen Virpi, Kiviharju Anna, Traynor Bryan, Tienari Pentti J, Hartikainen Päivi, Remes Anne M. 2015. PLoS ONE. 10: e0131817
The C90RF72 expansion does not affect the phenotype in Nasu-Hakola disease with the DAP12 mutation
Solje Eino, Hartikainen Päivi, Valori Miko, Vanninen Ritva, Tiihonen Jari, Hakola Panu, Tienari Pentti J, Remes Anne M. 2014. Neurobiology of aging. 35: 1780.e13-1780.e17

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Tarkenna hakuasi

Eino Solje

Tutkimusryhmät

Projektit

Ohjaukset (tohtorikoulutus ja opinnäytetyöt)

Työtehtävät

Tutkinnot

Avainsanat

Anti-GluA3 autoantibodies define a new sub-population of frontotemporal lobar degeneration patients with distinct neuropathological features

Evaluating the need for legal guardianship in people with dementia: gaining insight into professionals’ assessment criteria

‘Something is dropped out of the journey of life’: perceived spaces of opportunity among people with dementia

Amyotrophic Lateral Sclerosis in Southwestern and Eastern Finland

Incidence of Syndromes Associated With Frontotemporal Lobar Degeneration in 9 European Countries

Psychopharmacological Medication Use in Frontotemporal Dementia at the Time of Diagnosis: Comparison with Alzheimer’s Disease

Salivary Metabolomics in the Diagnosis and Monitoring of Neurodegenerative Dementia

Serum Cathepsin S Levels Do Not Show Alterations in Different Clinical, Neuropathological, or Genetic Subtypes of Frontotemporal Dementia Patients nor in Comparison to Healthy Control Individuals

Syljen metabolomiikan sovellutuksia suulääketieteellisessä tutkimuksessa

Traumatic Brain Injury Associates with an Earlier Onset in Sporadic Frontotemporal Dementia

Brainstem atrophy is linked to extrapyramidal symptoms in frontotemporal dementia

Cognitive impairment is not uncommon in patients with biallelic RFC1 AAGGG repeat expansion, but the expansion is rare in patients with cognitive disease

Increasing Brain Gamma Activity Improves Episodic Memory and Restores Cholinergic Dysfunction in Alzheimer's Disease

Lääkärinlausunto ratkaisijan pöydällä

Modifiable potential risk factors in familial and sporadic frontotemporal dementia

Serum total TDP-43 levels are decreased in frontotemporal dementia patients with C9orf72 repeat expansion or concomitant motoneuron disease phenotype

A Novel Genetic Marker for the C9orf72 Repeat Expansion in the Finnish Population

C9orf72 hexanucleotide repeat expansion leads to altered neuronal and dendritic spine morphology and synaptic dysfunction

Deficient neurotransmitter systems and synaptic function in frontotemporal lobar degeneration-Insights into disease mechanisms and current therapeutic approaches

Experimental Disease-Modifying Agents for Frontotemporal Lobar Degeneration

FRONTotemporal dementia Incidence European Research Study - FRONTIERS: Rationale and design

FTLD Patient-Derived Fibroblasts Show Defective Mitochondrial Function and Accumulation of p62

GFAP as a biomarker in frontotemporal dementia and primary psychiatric disorders: diagnostic and prognostic performance

Otsa-ohimolohkorappeumat

Otsa-ohimolohkorappeumat - miten tunnistan ja hoidan?

Primary progressive aphasias associated with C9orf72 expansions: Another side of the story

Serum GFAP and NfL levels in benign relapsing-remitting multiple sclerosis

State-of-the-Art Methods and Emerging Fluid Biomarkers in the Diagnostics of Dementia-A Short Review and Diagnostic Algorithm

Suuntana muistisairauden yksilöllinen varhaisdiagnostiikka ja hoito

BV-2 Microglial Cells Overexpressing C9orf72 Hexanucleotide Repeat Expansion Produce DPR Proteins and Show Normal Functionality but No RNA Foci

C9orf72 Repeat Expansion Does Not Affect the Phenotype in Primary Progressive Aphasia

Comparison of Prodromal Symptoms of Patients with Behavioral Variant Frontotemporal Dementia and Alzheimer Disease

Frontotemporal dementia: a conference report from the 2nd FinFTD Symposium

Huippuasiantuntijaksi ei kehity harjoittelemalla yksinäisyydessä

Serum neurofilament light chain in FTLD: association with C9orf72, clinical phenotype, and prognosis

The ethical implications of genetic testing in neurodegenerative diseases: A systematic review

Astrocytes and Microglia as Potential Contributors to the Pathogenesis of C9orf72 Repeat Expansion-Associated FTLD and ALS

Low Serum High-Density Lipoprotein Cholesterol Levels Associate with the C9orf72 Repeat Expansion in Frontotemporal Lobar Degeneration Patients

Mutation Analysis of the Genes Linked to Early Onset Alzheimer's Disease and Frontotemporal Lobar Degeneration

Neurologeilta hattutemppu - erikoislääkärikoulutus auditoitiin jo kolmannen kerran

Prodromal and Early bvFTD: Evaluating Clinical Features and Current Biomarkers

The Association Between Distinct Frontal Brain Volumes and Behavioral Symptoms in Mild Cognitive Impairment, Alzheimer's Disease, and Frontotemporal Dementia

Automatic MRI Quantifying Methods in Behavioral-Variant Frontotemporal Dementia Diagnosis

Low Prevalence of Cancer in Patients with Frontotemporal Lobar Degeneration

Otsalohkodementia - neurologian ja psykiatrian rajapinnalla

Otsalohkodementia - salakavala muistisairaus

Prevalence of immunological diseases in a Finnish frontotemporal lobar degeneration cohort with the C9orf72 repeat expansion carriers and non-carriers

Subtle Cognitive Impairment and Alzheimer's Disease-Type Pathological Changes in Cerebrospinal Fluid are Common Among Neurologically Healthy Subject

The association between frontotemporal lobar degeneration and bullous pemphigoid

Frontotemporal dementia as a comorbidity to idiopathic normal pressure hydrocephalus (iNPH): a short review of literature and an unusual case

Low Cerebrospinal Fluid Amyloid-Beta Concentration Is Associated with Poorer Delayed Memory Recall in Women

The C9ORF72 expansion sizes in patients with psychosis: a population-based study on the Northern Finland Birth Cohort 1966

The Spectrum of the Phenotypes in the C9ORF72 Expansion Carriers: Insights at the Interface between Neurology and Psychiatry

The role of the FTD-ALS associated C9orf72 expansion in suicide victims

Relationship between ubiquilin-1 and BACE1 in human Alzheimer's disease and APdE9 transgenic mouse brain and cell-based models

The phenotype of the C90RF72 Expansion carriers according to revised crieria for bvFTD

The C90RF72 expansion does not affect the phenotype in Nasu-Hakola disease with the DAP12 mutation