JAGADISH VANGIPURAPU

Yhteystiedot

Julkaisut

• Chen, J; Spracklen, CN; Marenne, G; Varshney, A; Corbin, LJ; Luan, J; Willems, SM; Wu, Y; Zhang, X; Horikoshi, M; Boutin, TS; Mägi, R; Waage, J; Li-Gao, R; Chan, KHK; Yao, J; Anasanti, MD; Chu, AY; Claringbould, A; Heikkinen, J; et al. [incl. Kuulasmaa, T; Kuusisto, J; Laakso, M; Lakka, T; Uusitupa, M; Vangipurapu, J]. 2021. The trans-ancestral genomic architecture of glycemic traits Nature genetics 53 6: 840-860. 2021
• Fernandes Silva, Lilian; Vangipurapu, Jagadish; Laakso, Markku. 2021. The "Common Soil Hypothesis" Revisited - Risk Factors for Type 2 Diabetes and Cardiovascular Disease Metabolites 11 10: 691. 2021
• Ganel, Liron; Chen, Lei; Christ, Ryan; Vangipurapu, Jagadish; Young, Erica; Das, Indraniel; Kanchi, Krishna; Larson, David; Regier, Allison; Abel, Haley; Kang, Chul Joo; Scott, Alexandra; Havulinna, Aki; Chiang, Charleston WK; Service, Susan; Freimer, Nelson; Palotie, Aarno; Ripatti, Samuli; Kuusisto, Johanna; Boehnke, Michael; Laakso, Markku; Locke, Adam; Stitziel, Nathan O; Hall, Ira M. 2021. Mitochondrial genome copy number measured by DNA sequencing in human blood is strongly associated with metabolic traits via cell-type composition differences Human genomics 15 1: 1-17. 2021
• Jauhiainen, Raimo; Vangipurapu, Jagadish; Laakso, Annamaria; Kuulasmaa, Teemu; Kuusisto, Johanna; Laakso, Markku. 2021. The association of nine amino acids with cardiovascular events in Finnish men in a 12-year follow-up study Journal of clinical endocrinology and metabolism 106 12: 3448-3454. 2021
• Tura, Andrea; Grespan, Eleonora; Göbl, Christian S; Koivula, Robert W; Franks, Paul W; Pearson, Ewan R; Walker, Mark; Forgie, Ian M; Giordano, Giuseppe N; Pavo, Imre; Ruetten, Hartmut; Dermitzakis, Emmanouil T; McCarthy, Mark I; Pedersen, Oluf; Schwenk, Jochen M; Adamski, Jerzy; De Masi, Federico; Tsirigos, Konstantinos D; Brunak, Søren; Viñuela, Ana et al. [incl. Kokkola, Tarja; Vangipurapu Jaga. 2021. Profiles of glucose metabolism in different prediabetes phenotypes, classified by fasting glycemia, 2-hour OGTT, glycated hemoglobin, and 1-hour OGTT: An IMI DIRECT study Diabetes 70 96: 2092-2106. 2021
• Atabaki-Pasdar, Naeimeh; Ohlsson, Mattias; Viñuela, Ana; Frau, Francesca; Pomares-Millan, Hugo; Haid, Mark; Jones, Angus G; Thomas, E Louise; Koivula, Robert W; Kurbasic, Azra; Mutie, Pascal M; Fitipaldi, Hugo; Fernandez, Juan; Dawed, Adem Y; Giordano, Giuseppe N; Forgie, Ian M; McDonald, Timothy J; Rutters, Femke; Cederberg, Henna; Chabanova, Elizaveta et al. [Incl. Kokkola, Tarja; Laakso Markku;. 2020. Predicting and elucidating the etiology of fatty liver disease: A machine learning modeling and validation study in the IMI DIRECT cohorts PLoS medicine 17 6: e1003149. 2020
• Bar, Noam; Korem, Tal; Weissbrod, Omer; Zeevi, David; Rothschild, Daphna; Leviatan, Sigal; Kosower, Noa; Lotan-Pompan, Maya; Weinberger, Adina; Le Roy, Caroline I; Menni, Cristina; Visconti, Alessia; Falchi, Mario; Spector, Tim D; Adamski, Jerzy; Franks, Paul W; Pedersen, Oluf; Segal, Eran; The IMI DIRECT Consortium [incl. Kuulasmaa, Teemu; Kokkola, Tarja; Laakso, Markku; Vangipurapu, Jagadish; Ce. 2020. A reference map of potential determinants for the human serum metabolome. Nature 588: 135-140. 2020
• Fernandes Silva, Lilian; Vangipurapu, Jagadish; Smith, Ulf; Laakso, Markku. 2020. Metabolite signature of albuminuria involves amino acid pathways in 8,661 Finnish men without diabetes Journal of clinical endocrinology and metabolism 2021; 106 1: 143-152. 2020
• Jauhiainen, Raimo; Jauhiainen, Matti; Vangipurapu, Jagadish; Kuulasmaa, Teemu; Ala-Korpela, Mika; Laakso, Markku; Kuusisto, Johann. 2020. Novel biomarkers associated with incident heart failure in 10 106 Finnish men ESC heart failure 2021; 8 1: 605-614. 2020
• Vangipurapu, Jagadish; Fernandes Silva, Lilian; Kuulasmaa, Teemu; Smith, Ulf; Laakso, Markku. 2020. Microbiota-Related Metabolites and the Risk of Type 2 Diabetes Diabetes care 43 6: 1319-1325. 2020
• Clark, DW; Okada, Y; Moore, KHS; Mason, D; Pirastu, N; Gandin, I; Mattsson, H; Barnes, CLK; Lin, K; Zhao, JH; Deelen, P; Rohde, R; Schurmann, C; Guo, X; Giulianini, F; Zhang, W; Medina-Gomez, C; Karlsson, R; Bao, Y; Bartz, TM; et al. [incl. Kuusisto, J; Laakso, M; Vangipurapu, J; Yaluri, A]. 2019. Associations of autozygosity with a broad range of human phenotypes Nature communications 10 1: 4957. 2019
• Evangelou E; Gao, H; Chu, C; Ntritsos, G; Blakeley, P; Butts, AR; Pazoki, R; Suzuki, H; Koskeridis, F; Yiorkas, AM; Karaman, I; Elliott, J; Luo, Q; Aeschbacher, S; Bartz, TM; Baumeister, SE; Braund, PS; Brown, MR; Brody, JA; Clarke TK; et al. (Incl. Yaluri, A; Kuusisto, J; Laakso, M; Vangipurapu, J). 2019. New alcohol-related genes suggest shared genetic mechanisms with neuropsychiatric disorders Nature human behaviour 3 9: 950-961. 2019
• Fernandes, Silva L; Vangipurapu, J; Kuulasmaa, T; Laakso, M. 2019. An intronic variant in the GCKR gene is associated with multiple lipids Scientific reports 9: 10240. 2019
• Jääskeläinen, P; Vangipurapu, J; Raivo, J; Kuulasmaa, T; Heliö, T; Aalto-Setälä, K; Kaartinen, M; Ilveskoski, E; Vanninen, S; Hämäläinen, L; Melin, J; Kokkonen, J; Nieminen, MS; FinHCM Study Group; Laakso, M; Kuusisto, J. 2019. Genetic basis and outcome in a nationwide study of Finnish patients with hypertrophic cardiomyopathy ESC heart failure 6 3: 436-445. 2019
• Locke, AE; Steinberg, KM; Chiang, CWK; Service, SK; Havulinna, AS; Stell, L; Pirinen, M; Abel, HJ; Chiang, CC; Fulton, RS; Jackson, AU; Kang, CJ; Kanchi, KL; Koboldt, DC; Larson, DE; Nelson, J; Nicholas, TJ; Pietilä, A; Ramensky, V; Ray, D; et al. (incl. Laakso, M; Ala-Korpela, M; Vangipurapu, J). 2019. Exome sequencing of Finnish isolates enhances rare-variant association power Nature 572: 323-328. 2019
• Vangipurapu, J; Stancáková, A; Smith, U; Kuusisto, J; Laakso, M. 2019. Nine Amino Acids are Associated with Decreased Insulin Secretion and Elevated Glucose Levels in a 4.6-Year Follow-Up Study of 5,181 Finnish Men Diabetes 68 6: 1353-1358. 2019
• López Rodríguez, Maykel; Fernandes Silva, Lilian; Vangipurapu, Jagadish; Modi, Shalem; Kuusisto, Johanna; Kaikkonen, Minna U; Laakso, Markku. 2018. Functional Variant in the GCKR Gene Affects Lactate Levels Differentially in the Fasting State and During Hyperglycemia Scientific Reports 8 1: 15989. 2018
• Huopio Hanna, Miettinen Päivi J, Ilonen Jorma, Nykänen Päivi, Veijola Riitta, Keskinen Päivi, Näntö-Salonen Kirsti, Vangipurapu Jagadish, Raivo Joose, Stancáková Alena, Männistö Jonna, Kuulasmaa Teemu, Knip Mikael, Otonkoski Timo, Laakso Markku. 2016. Clinical, Genetic, and Biochemical Characteristics of Early-Onset Diabetes in the Finnish Population. JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 101 8: 3018-3026. 2016
• Löf Christoffer, Patyra Konrad, Kuulasmaa Teemu, Vangipurapu Jagadish, Undeutsch Henriette, Jäschke Holger, Pajunen Tuulia, Kero Andreina, Krude Heiko, Biebermann Heike, Kleinau Gunnar, Kühnen Peter, Rantakari Krista, Miettinen Päivi, Kirjavainen Turkka, Pursiheimo Juha-Pekka, Mustila Taina, Jääskeläinen Jarmo, Ojaniemi Marja, Toppari Jorma et al. 2016. Detection of novel gene variants associated with congenital hypothyroidism in a Finnish patient cohort. THYROID 26 9: 1215-1224. 2016
• Vangipurapu Jagadish, Stancakova Alena, Jauhiainen Raimo, Kuusisto Johanna, Laakso Markku. 2016. Short adult stature predicts impaired beta-cell function, insulin resistance, glycemia and type 2 diabetes in Finnish men Journal of clinical endocrinology and metabolism 2017: 102 2: 443-450. 2016
• Vangipurapu Jagadish, Stancáková Alena, Kuulasmaa Teemu, Kuusisto Johanna, Laakso Markku. 2015. Both fasting and glucose-stimulated proinsulin levels predict hyperglycemia and incident type 2 diabetes: a population-based study of 9,396 finnish men. PLOS ONE [ONLINE] 10 4: e0124028. 2015
• Yaghootkar Hanieh, Stancáková Alena, Freathy Rachel M, Vangipurapu Jagadish, Weedon Michael N, Xie Weijia, Wood Andrew R, Ferrannini Ele, Mari Andrea, Ring Susan M, Lawlor Debbie A, Smith George Davey, Jørgensen Torben, Hansen Torben, Pedersen Oluf, Steinthorsdottir Valgerdur, Guðbjartsson Daniel F, Thorleifsson Gudmar, Thorsteinsdottir Unnur, Stefansson Kari et al. 2015. Association analysis of 29,956 individuals confirms that a low-frequency variant at CCND2 halves the risk of type 2 diabetes by enhancing insulin secretion. DIABETES (NY) 64 6: 2279-2285. 2015
• Fízelóvá Maria, Cederberg Henna, Stancakova Alena, Jauhiainen Raimo, Vangipurapu Jagadish, Kuusisto Johanna, Laakso Markku. 2014. Markers of tissue-specific insulin resistance predict the worsening of hyperglycemia, incident type 2 diabetes and cardiovascular disease. PLOS ONE [ONLINE] 9 10: e109772. 2014
• Cederberg H, Gylling H, Miettinen TA, Paananen J, Vangipurapu J, Pihlajamäki J, Kuulasmaa T, Stancáková A, Smith U, Kuusisto J, Laakso M. 2013. Non-cholesterol sterol levels predict hyperglycemia and conversion to type 2 diabetes in finnish men. PLOS ONE [ONLINE] 8 6: e67406. 2013
• Huopio H, Cederberg H, Vangipurapu J, Hakkarainen H, Pääkkönen M, Kuulasmaa T, Heinonen S, Laakso M. 2013. Association of risk variants for type 2 diabetes and hyperglycemia with gestational diabetes. EUROPEAN JOURNAL OF ENDOCRINOLOGY 169 3: 291-297. 2013
• Mahendran Y, Vangipurapu J, Cederberg H, Stancáková A, Pihlajamäki J, Soininen P, Kangas AJ, Paananen J, Civelek M, Saleem NK, Pajukanta P, Lusis AJ, Bonnycastle LL, Morken MA, Collins FS, Mohlke KL, Boehnke M, Ala-Korpela M, Kuusisto J, Laakso M. 2013. Association of ketone body levels with hyperglycemia and type 2 diabetes in 9,398 Finnish men. DIABETES (NY) 62: 3618-3626. 2013
• Mahendran Y, Ågren J, Uusitupa M, Cederberg H, Vangipurapu J, Stancakova A, Schwab U, Kuusisto J, Laakso M. 2013. Association of erythrocyte membrane fatty acids with changes in glycemia and risk of type 2 diabetes. AMERICAN JOURNAL OF CLINICAL NUTRITION -: -. 2013
• Mahendran Yuvaraj, Cederberg Henna, Vangipurapu Jagadish, Kangas Antti J, Soininen Pasi, Kuusisto Johanna, Uusitupa Matti, Ala-Korpela Mika, Laakso Markku. 2013. Glycerol and fatty acids in serum predict the development of hyperglycemia and type 2 diabetes in Finnish men. DIABETES CARE 36: 3732-3738. 2013
• Vangipurapu J. 2012. Liver insulin resistance and hyperglycemia: Genetic determinants and association with cardiovascular risk factors. 2012
• Vangipurapu Jagadish, Stančáková A, Kuulasmaa Teemu, Soininen Pasi, Kangas AJ, Ala-Korpela Mika, Kuusisto Johanna, Laakso Markku. 2012. Association between liver insulin resistance and cardiovascular risk factors JOURNAL OF INTERNAL MEDICINE 272: 402-408. 2012
• Vangipurapu J, Stancakova A, Kuulasmaa T, Paananen J, Kuusisto J, EGIR-RISC Study Group, Ferrannini E, Laakso M. 2011. A novel surrogate index for hepatic insulin resistance DIABETOLOGIA 54: 540-543. 2011
• Vangipurapu J, Stancakova A, Pihlajamäki J, Kuulasmaa TM, Kuulasmaa T, Paananen J, Kuusisto J, Ferrannini E, Laakso M. 2011. Association of indices of liver and adipocyte insulin resistance with 19 confirmed susceptibility loci for type 2 diabetes in 6,733 non-diabetic Finnish men DIABETOLOGIA 54: 563-571. 2011