Jyrki Ågren

Lankinen, MA; de Mello, VD; Meuronen, T; Sallinen, T; Ågren, J; Virtanen, KA; Laakso, M; Pihlajamäki, J; Schwab, U. 2021. The FADS1 Genotype Modifes Metabolic Responses to the Linoleic Acid and Alpha-linolenic Acid Containing Plant Oils-Genotype Based Randomized Trial FADSDIET2 Molecular nutrition and food research 65 7: 2001004. 2021

Eloranta, Aino-Maija; Sallinen, Taisa; Viitasalo, Anna; Lintu, Niina; Väistö, Juuso; Jalkanen, Henna; Tompuri, Tuomo T; Soininen, Sonja; Haapala, Eero A; Kiiskinen, Sanna; Schnurr, Theresia M; Kilpeläinen, Tuomas O; Mikkonen, Santtu; Savonen, Kai; Atalay, Mustafa; Brage, Soren; Laaksonen, David E; Lindi, Virpi; Ågren, Jyrki; Schwab, Ursula; et al. [incl. Jääskeläinen, Jarmo; Lakka, Timo]. 2020. The effects of a 2-year physical activity and dietary intervention on plasma lipid concentrations in children: the PANIC Study European journal of nutrition 2021; 60: 425-434. 2020

Lankinen, MA; Fauland, A; Shimizu, BI; Ågren, J; Wheelock, CE; Laakso, M; Schwab, U; Pihlajamäki, J. 2019. Inflammatory response to dietary linoleic acid depends on FADS1 genotype American journal of clinical nutrition 109 1: 165-175. 2019

Manninen, S; Lankinen, M; de Mello, V; Ågren, J; Laaksonen, D; Schwab, U; Erkkilä, A. 2018. The effect of camelina sativa oil and fish intakes on fatty acid compositions of blood lipid fractions NUTRITION, METABOLISM AND CARDIOVASCULAR DISEASES 2019; 29 1: 51-61. 2018

Mäntyselkä, A; Lindi, V; Viitasalo, A; Eloranta, AM; Ågren, J; Väisänen, S; Voutilainen, R; Laitinen, T; Lakka, TA; Jääskeläinen, J. 2018. Associations of Dehydroepiandrosterone Sulfate with Cardiometabolic Risk Factors in Prepubertal Children JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 103 7: 2592-2600. 2018

Vaittinen M, Männistö V, Käkelä P, Ågren J, Tiainen M, Schwab U, Pihlajamäki J. 2017. Interorgan cross talk between fatty acid metabolism, tissue inflammation, and FADS2 genotype in humans with obesity. OBESITY (SILVER SPRING, MD.) 25 3: 545-552. 2017

Walle P, Takkunen M, Männistö V, Vaittinen M, Käkelä P, Ågren J, Schwab U, Lindström J, Tuomilehto J, Uusitupa M, Pihlajamäki J. 2017. Alterations in fatty acid metabolism in response to obesity surgery combined with dietary counseling. NUTRITION AND DIABETES 7 9: e285. 2017

Haapala EA, Viitasalo A, Venäläinen T, Eloranta AM, Ågren J, Lindi V, Lakka TA. 2016. Plasma polyunsaturated fatty acids are directly associated with cognition in overweight children but not in normal weight children. ACTA PAEDIATRICA 105 12: 1502-1507. 2016

Venäläinen Taisa M, Viitasalo Anna M, Schwab Ursula S, Eloranta Aino-Maija, Haapala Eero A, Jalkanen Henna P, de Mello Vanessa DF, Laaksonen David E, Lindi Virpi I, Ågren Jyrki J, Lakka Timo A. 2016. Effect of a 2-y dietary and physical activity intervention on plasma fatty acid composition and estimated desaturase and elongase activities in children: the Physical Activity and Nutrition in Children Study. AMERICAN JOURNAL OF CLINICAL NUTRITION 104 4: 964-972. 2016

Walle Paula, Takkunen Markus, Männistö Ville, Vaittinen Maija, Lankinen Maria, Kärjä Vesa, Käkelä Pirjo, Ågren Jyrki, Tiainen Mika, Schwab Ursula, Kuusisto Johanna, Laakso Markku, Pihlajamäki Jussi. 2016. Fatty acid metabolism is altered in non-alcoholic steatohepatitis independent of obesity. METABOLISM 65 5: 655-666. 2016

Lankinen Maria A, Stancáková Alena, Uusitupa Matti, Ågren Jyrki, Pihlajamäki Jussi, Kuusisto Johanna, Schwab Ursula, Laakso Markku. 2015. Plasma fatty acids as predictors of glycaemia and type 2 diabetes. DIABETOLOGIA 58 11: 2533-2544. 2015

Pihlajamäki Jussi, Schwab Ursula, Kaminska Dorota, Ågren Jyrki, Kuusisto Johanna, Kolehmainen Marjukka, Paananen Jussi, Laakso Markku, Uusitupa Matti. 2015. Dietary polyunsaturated fatty acids and the Pro12Ala polymorphisms of PPARG regulate serum lipids through divergent pathways: a randomized crossover clinical trial. Genes and Nutrition 10 6: 43. 2015

Takkunen Markus J, de Mello Vanessa D, Schwab Ursula S, Kuusisto Johanna, Vaittinen Maija, Ågren Jyrki J, Laakso Markku, Pihlajamäki Jussi, Uusitupa MI. 2015. Gene-diet interaction of a common FADS1 variant with marine polyunsaturated fatty acids for fatty acid composition in plasma and erythrocytes among men. Molecular Nutrition & Food Research 2016; 60 2: 381-389. 2015

Vaittinen Maija, Walle Paula, Kuosmanen Emmi, Männistö Ville, Käkelä Pirjo, Ågren Jyrki, Schwab Ursula, Pihlajamäki Jussi. 2015. FADS2 genotype regulates delta-6 desaturase activity and inflammation in human adipose tissue. JOURNAL OF LIPID RESEARCH 2016; 57: 56-65. 2015

Venäläinen Taisa, Ågren Jyrki, Schwab Ursula, de Mello Vanessa D, Eloranta Aino-Maija, Laaksonen David E, Lindi Virpi, Lakka Timo A. 2015. Cross-sectional associations of plasma fatty acid composition and estimated desaturase and elongase activities with cardiometabolic risk in Finnish children - The PANIC study. Journal of Clinical Lipidology 2016; 10 1: 82-91. 2015

Viitasalo A, Ågren J, Venäläinen T, Pihlajamäki J, Jääskeläinen J, Korkmaz A, Atalay M, Lakka TA. 2015. Association of plasma fatty acid composition with plasma irisin levels in normal weight and overweight/obese children. PEDIATRIC OBESITY 2015; 11 4: 299-305. 2015

Väistö J, Eloranta A-M, Viitasalo A, Tompuri T, Lintu N, Karjalainen P, Lampinen E-K, Ågren J, Laaksonen DE, Lakka H-M, Lindi V, Lakka TA. 2014. Physical activity and sedentary behaviour in relation to cardiometabolic risk in children: cross-sectional findings from the Physical Activity and Nutrition in Children (PANIC) Study. INTERNATIONAL JOURNAL OF BEHAVIORAL NUTRITION AND PHYSICAL ACTIVITY 11 1: 55. 2014

Takkunen MJ, de Mello VDF, Schwab US, Ågren JJ, Kuusisto J, Uusitupa MIJ. 2014. Associations of erythrocyte membrane fatty acids with the concentrations of C-reactive protein, interleukin 1 receptor antagonist and adiponectin in1373 men. PROSTAGLANDINS, LEUKOTRIENES AND ESSENTIAL FATTY ACIDS 91: 169-174. 2014

Venäläinen Taisa, Schwab Ursula, Ågren Jyrki, de Mello Vanessa, Lindi Virpi, Eloranta Aino-Maija, Kiiskinen Sanna, Laaksonen David, Lakka Timo A. 2014. Cross-Sectional Associations of Food Consumption with Plasma Fatty Acid Composition and Estimated Desaturase Activities in Finnish Children. LIPIDS 49 5: 467-479. 2014

Mahendran Y, Ågren J, Uusitupa M, Cederberg H, Vangipurapu J, Stancakova A, Schwab U, Kuusisto J, Laakso M. 2013. Association of erythrocyte membrane fatty acids with changes in glycemia and risk of type 2 diabetes. AMERICAN JOURNAL OF CLINICAL NUTRITION -: -. 2013

Takkunen M, Ågren J, Kuusisto J, Laakso M, Uusitupa M, Schwab U. 2013. Dietary fat in relation to erythrocyte fatty acid composition in men. LIPIDS 48: 1093-1102. 2013

Schwab U, Seppänen-Laakso T, Yetukuri L, Ågren J, Kolehmainen M, Laaksonen DE, Ruskeepää A-L, Gylling H, Uusitupa M, Oresic M, for the Genobin Study Group, Schwab U, Kolehmainen M, Gylling H, Uusitupa M. 2008. Triacylglycerol fatty acid composition in diet-induced weight loss in subjects with abnormal glucose metabolism - the GENOBIN study. PLOS ONE [ONLINE] 3 7: e2630. 2008

Erkkilä AT, Schwab US, Ågren JJ, Hallikainen M, Gylling H, Uusitupa MIJ, Schwab US, Uusitupa MIJ. 2007. Moderate increase in dietary sucrose does not influence fasting or postprandial serum lipids regardless of the presence of apolipoprotein E2 allele in healthy subjects EUROPEAN JOURNAL OF CLINICAL NUTRITION 61: 1094-1101. 2007

Gylling H, Hallikainen M, Kolehmainen M, Toppinen L, Pihlajamäki J, Mykkänen H, Ågren JJ, Rauramaa R, Laakso M, Miettinen TA. 2007. Cholesterol synthesis prevails over absorption in metabolic syndrome. TRANSLATIONAL RESEARCH 149: 310-316. 2007

Sittiwet C, Gylling H, Hallikainen M, Pihlajamäki J, Moilanen L, Laaksonen DE, Niskanen L, Ågren JJ, Laakso M, Miettinen TA. 2007. Cholesterol metabolism and non-cholesterol sterol distribution in lipoproreins of type 1 diabetes: The effect of improved glycemic control. ATHEROSCLEROSIS 194: 465-472. 2007

Hallikainen M, Vidgren H, Ågren JJ, Kiviniemi V, Miettinen TA, Gylling H. 2006. Postprandial behavior of plasma squalene and non-cholesterol sterols in men with varying cholesterol sbsorbtion. CLINICA CHIMICA ACTA (AMSTERDAM) 374: 63-68. 2006

Ågren JJ, Hallikainen M, Vidgren H, Miettinen TA, Gylling H. 2006. Postprandial lipemic response and lipoprotein composition in subjects with low or high cholesterol absorption efficiency. CLINICA CHIMICA ACTA (AMSTERDAM) 366: 309-315. 2006

Gylling HK, Hallikainen M, Vidgren H, Ågren J. 2006. Ester percentages of plant sterols and cholesterol in chylomicrons and VLDL of humans with low and high sterol absorption. ATHEROSCLEROSIS 187: 150-152. 2006

Hallikainen M, Toppinen L, Mykkänen H, Ågren JJ, Laaksonen DE, Miettinen TA, Niskanen L, Poutanen KS, Gylling H, Poutanen KS. 2006. Interaction between cholesterol and glucose metabolism during dietary carbohydrate midification in subjects with the metabolic syndrome 1-3. AMERICAN JOURNAL OF CLINICAL NUTRITION 84: 1385-1392. 2006

Hallikainen M, Lyyra-Laitinen T, Laitinen T, Ågren JJ, Pihlajamäki J, Rauramaa R, Miettinen TA, Gylling H. 2006. Endothelial function in hypercholesterolemic subjects: Effects of plant stanol and sterol esters ATHEROSCLEROSIS 188: 425-432. 2006

Ågren JJ, Kurvinen J-P, Kuksis A. 2005. Isolation of very low density lipiprotein phospholipids enriched in ethanolamine phospholipids from rats with Triton WR 1339. BIOCHIMICA ET BIOPHYSICA ACTA 1734: 34-43. 2005

Chatzifotis S, Muje P, Pavlidis M, Ågren J, Paalavuo M, Mölsä H. 2004. Evolution of tissue composition and serum metabolites during gonadal development in the common dentex (Dentex dentex) AQUACULTURE 236: 557-573. 2004

Gylling H, Hallikainen M, Pihlajamäki J, Ågren J, Laakso M, Rajaratnam RA, Rauramaa R, Miettinen TA, Laakso M. 2004. Polymorphisms in the ABCG5 and ABCG8 genes associate with cholesterol absorbtion and insulin sensitivity. JOURNAL OF LIPID RESEARCH 45: 1660-1665. 2004

Ågren JJ, Ravandi A, Kuksis A, Steiner G. 2002. Structural and compositional changes in very low density lipoprotein triacylglycerols during basal lipolysis. FEBS JOURNAL 269: 6223-6232. 2002

Schwab US, Ågren JJ, Valve R, Hallikainen MA, Sarkkinen ES, Jauhiainen M, Karvonen MK, Pesonen U, Koulu M, Uusitupa MIJ, Savolainen MJ. 2002. The impact of the leucine 7 to proline 7 polymorphism of the neuropeptide Y gene on postprantial lipemia and on the response of serum total and lipoprotein lipids to a reduced fat diet EUROPEAN JOURNAL OF CLINICAL NUTRITION 56: 149-156. 2002

Ågren JJ, Kuksis A. 2002. Analysis of diastereomeric DAG napthylethylurethanes by normal-phase HPLC with on-line electrospray MS LIPIDS 37 6: 613-619. 2002

Ågren JJ, Tvrzicka E, Nenonen MT, Helve T, Hänninen O. 2001. Divergent changes in serum sterols during a strict uncooked vegan diet in patients with rheumatoid arthritis. BRITISH JOURNAL OF NUTRITION 85: 137-139. 2001

Ågren JJ, Vidgren HM, Valve RS, Laakso M, Uusitupa MI. 2001. Postprandial responses of individual fatty acids in subjects homozygous for the threonine- or alanine-encoding allele in codon 54 of the intestinal fatty acid binding protein 2 gene 1,2 AMERICAN JOURNAL OF CLINICAL NUTRITION 73: 31-35. 2001

Hänninen O, Nenonen M, Ågren J, Kaartinen K, Atalay M. 2000. Kasvisruokavaliot nousemassa suosioon. SUOMEN LÄÄKÄRILEHTI 55 35: 3469-3473. 2000

Krasnov A, Ågren JJ, Pitkänen TI, Mölsä H. 1999. Transfer of growth hormone (GH) transgenes into Arctic charr (Salvelinus alpinus L.) : II. Nutrient partitioning in rapidly growing fish. GENETIC ANALYSIS - BIOMOLECULAR ENGINEERING 15: 99-105. 1999

Vidgren HM, Ågren JJ, Valve RS, Karhunen LJ, Rissanen AM, Uusitupa MIJ. 1999. The effect of orlistat on the fatty acid composition of serum lipid fractions in obese subjects. CLINICAL PHARMACOLOGY AND THERAPEUTICS 66: 315-322. 1999

Paalavuo M, Muje P, Ågren J, Tambets M. 1998. Energy content and fatty acid composition of vendace (Coregonus albula L.) gonads in four Finnish and Estonian lakes: Eckmann R, Appenzeller A, Rösch R, Biology and Management of Coregonid Fishes -- 1996. Proceedings of the Sixth International Symposium.Schweizerbart'sche Verlagsbuchhandlung . Advances in Limnology. 25-32. 1998

Vidgren HM, Louheranta AM, Ågren JJ, Schwab US, Uusitupa MIJ. 1998. Divergent incorporation of dietary trans fatty acids in different serum lipid fractions. LIPIDS 33 10: 955-962. 1998

Ågren JJ, Valve R, Vidgren H, Laakso M, Uusitupa M. 1998. Postprandial lipemic response is modified by the polymorphism at codon 54 of the fatty acid-binding protein 2 gene. ARTERIOSCLEROSIS, THROMBOSIS AND VASCULAR BIOLOGY 18: 1606-1610. 1998

Sen CK, Atalay M, Ågren J, Laaksonen DE, Roy S, Hänninen O. 1997. Fish oil and vitamin E supplementation in oxidative stress at rest and after physical exercise rest and after physical exercise. JOURNAL OF APPLIED PHYSIOLOGY 83 1: 189-195. 1997

Vidgren HM, Ågren JJ, Schwab U, Rissanen T, Hänninen O, Uusitupa MIJ. 1997. Incorporation of n-3 fatty acids into plasma lipid fractions, and erythrocyte membranes and platelets during dietary supplementation with fish, fish oil, and docosahexaenoic acid-rich oil among healthy young men. LIPIDS 32 7: 697-705. 1997

Ågren JJ, Väisänen S, Hänninen O, Muller AD, Hornstra G. 1997. Hemostatic factors and platelet aggregation after a fish-enriched diet or fish oil or docosahexaenoic acid supplementation. PROSTAGLANDINS, LEUKOTRIENES AND ESSENTIAL FATTY ACIDS 57 4 & 5: 419-421. 1997

Vidgren HM, Niskanen LK, Erkkilä AT, Ågren JJ, Uusitupa MIJ. 1996. Altered fatty acid composition of serum lipids in patients with non-insulin-dependent diabetes. NUTRITION, METABOLISM AND CARDIOVASCULAR DISEASES 6: 219-226. 1996

Ågren JJ, Hänninen O, Julkunen A, Fogelholm L, Vidgren H, Schwab U, Pynnönen O, Uusitupa M. 1996. Fish diet, fish oil and docosahexaenoic acid rich lower fasting and postprandial plasma lipid levels EUROPEAN JOURNAL OF CLINICAL NUTRITION 50: 765-771. 1996

Zhu ZR, Ågren J, Männistö S, Pietinen P, Eskelinen M, Syrjänen K, Uusitupa M. 1995. Fatty acid composition of breast adipose tissue in breast cancer patients and in patients with bening breast disease. NUTRITION AND CANCER 24: 151-160. 1995

Ågren JJ, Törmälä M-L, Nenonen MT, Hänninen OO. 1995. Fatty acid composition of erythrocyte, platelet, and serum lipids in strict vegans. LIPIDS 30 4: 365-369. 1995

Uusitupa M, Schwab U, Mäkimattila S, Karhapää P, Sarkkinen E, Maliranta H, Ågren J, Penttilä I. 1994. Effects of two high-fat diets with different fatty acid compositions on glucose and lipid metabolism in healthy young women. AMERICAN JOURNAL OF CLINICAL NUTRITION 59: 1310-1316. 1994

Orlov SN, Ågren JJ, Hänninen OO, Nenonen MT, Lietava J, Rauma A-L, Cragoe EJ Jr. 1994. Univalent cation fluxes in human erythrocytes from individuals with low or normal sodium intake EUROPEAN JOURNAL OF CARDIOVASCULAR PREVENTION AND REHABILITATION 1: 249-254. 1994

Sarkkinen ES, Ågren JJ, Ahola I, Ovaskainen M-L, Uusitupa MIJ. 1994. Fatty acid composition of serum cholesterol esters, and erythrocyte and platelet membranes as indicators of long-term adherence to fat-modified diets. AMERICAN JOURNAL OF CLINICAL NUTRITION 59: 364-70. 1994

Ågren J, Hänninen O. 1993. Effects of cooking on the fatty acids of three freshwater fish species. FOOD CHEMISTRY 46: 337-382. 1993

Ågren JJ, Julkunen A, Penttilä I. 1992. Rapid separation of serum lipids for fatty acid analysis by a single aminopropyl column JOURNAL OF LIPID RESEARCH 33: 1871-1876. 1992

Ågren J, Al-Amad H, Hänninen O. 1991. Fatty acid content and composition of five fish species from the Persian Gulf 100B 2: 339-341. 1991

Ågren J, Hänninen O. 1991. Effects of moderate freshwater fish diet on erythrocyte ghost phospholipid fatty acids. Annals of Medicine 23: 261-263. 1991

Ågren J, Pekkarinen H, Litmanen H, Hänninen O. 1991. Fish diet and physical fitness in relation to membrane and serum lipids, prostanoid metabolism and platelet aggregation in female students. EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY 63: 393-398. 1991

Ågren J. 1991. n-3 fatty acids and lipid metabolism. Responses of human subjects to moderate fish diet. 1991

Hessel E, Ågren J, Paulitschke M, Hänninen O, Hänninen A, Lerche D. 1990. Freshwater fish diet affects lipid composition, deformability and aggregation properties of erythrocytes. ATHEROSCLEROSIS 82: 37-42. 1990

Ågren J, Hänninen O, Hänninen A, Seppänen K. 1990. Dose responses in platelet fatty acid composition, aggregation and prostanoid metabolism during moderate freshwater fish diet 57: 565-575. 1990

Blanck J, Lindström-Seppä P, Ågren J, Hänninen O, Rein H, Ruckpaul K. 1989. Temperature compensation of hepatic microsomal cytochrome P-450 activity in rainbow trout. I. Thermodynamic regulation during water cooling in autumn 93C: 55-60. 1989

Hänninen O, Ågren J, Laitinen M, Jääskeläinen I, Penttilä I. 1989. Dose-response relationships in blood lipids during moderate freshwater fish diet ANNALS OF MEDICINE (HELSINKI) 21: 203-207. 1989

Hänninen O, Ågren J. 1989. Effects of moderate freshwater fish diet on lipid metabolism of Finnish students 225: 77-81. 1989

Muje P, Ågren J, Lindqvist O, Hänninen O. 1989. Fatty acid composition of vendace (Coregonus albula L.) muscle and its plankton feed 92B: 75-79. 1989

Muje P, Ågren JJ, Lindqvist OV, Hänninen O. 1989. Fatty composition of vendace (coregonus Albula L.) muscle and its plankton feed 92B: 75-79. 1989

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