Marjo Tuomainen

Cold-stimulated brown adipose tissue activation is related to changes in serum metabolites relevant to NAD+ metabolism in humans

U-Din, Mueez; de Mello, Vanessa D; Tuomainen, Marjo; Raiko, Juho; Niemi, Tarja; Fromme, Tobias; Klåvus, Anton; Gautier, Nadine; Haimilahti, Kimmo; Lehtonen, Marko; Kristiansen, Karsten; Newman, John W; Pietiläinen, Kirsi H; Pihlajamäki, Jussi; Amri, Ez-Zoubir; Klingenspor, Martin; Nuutila, Pirjo; Pirinen, Eija; Hanhineva, Kati; Virtanen, Kirsi A. 2023. Cell reports. 42:

Topical pharmacokinetics of dexamethasone suspensions in the rabbit eye: Bioavailability comparison

Naageshwaran, Vatsala; Ranta, Veli-Pekka; Toropainen, Elisa; Tuomainen, Marjo; Gum, Glenwood; Xie, Enli; Bhoopathy, Siddhartha; Urtti, Arto; del Amo, Eva M. 2022. International journal of pharmaceutics. 615:

Understanding dexamethasone kinetics in the rabbit tear fluid: Drug release and clearance from solution, suspension and hydrogel formulations

Balla, Anusha; Ruponen, Marika; Valtari, Annika; Toropainen, Elisa; Tuomainen, Marjo; Alvarez-Lorenzo, Carmen; del Amo, Eva M.; Urtti, Arto; Vellonen, Kati-Sisko. 2022. European journal of pharmaceutics and biopharmaceutics. 172: 53-60

Indole-3-Propionic Acid, a Gut-Derived Tryptophan Metabolite, Associates with Hepatic Fibrosis

Sehgal, Ratika Ilha, Mariana Vaittinen, Maija Kaminska, Dorota Männistö, Ville Kärjä, Vesa Tuomainen, Marjo Hanhineva, Kati Romeo, Stefano Pajukanta, Päivi Pihlajamäki, Jussi de Mello, Vanessa D.. 2021. Nutrients. 13: 3509

"notame": Workflow for Non-Targeted LC-MS Metabolic Profiling

Klåvus, Anton; Kokla, Marietta; Noerman, Stefania; Koistinen, Ville M; Tuomainen, Marjo; Zarei, Iman; Meuronen, Topi; Häkkinen, Merja R; Rummukainen, Soile; Farizah Babu, Ambrin; Sallinen, Taisa; Kärkkäinen, Olli; Paananen, Jussi; Broadhurst, David; Brunius, Carl; Hanhineva, Kati. 2020. Metabolites. 10: 135

Side-stream products of malting: a neglected source of phytochemicals

Koistinen, Ville M; Tuomainen, Marjo; Lehtinen, Pekka; Peltola, Petri; Auriola, Seppo; Jonsson, Karin; Hanhineva, Kati. 2020. npj science of food. 4: 21

Quantitative assessment of betainized compounds and associations with dietary and metabolic biomarkers in the randomized study of the healthy Nordic diet (SYSDIET)

Tuomainen, M; Kärkkäinen, O; Leppänen, J; Auriola, S; Lehtonen, M; Savolainen, MJ; Hermansen, K; Risérus, U; Åkesson, B; Thorsdottir, I; Kolehmainen, M; Uusitupa, M; Poutanen, K; Schwab, U; Hanhineva, K. 2019. American journal of clinical nutrition. 110: 1108-1118

Associations of serum indolepropionic acid, a gut microbiota metabolite, with type 2 diabetes and low-grade inflammation in high-risk individuals

Tuomainen, Marjo; Lindström, Jaana; Lehtonen, Marko; Auriola, Seppo; Pihlajamäki, Jussi; Peltonen, Markku; Tuomilehto, Jaakko; Uusitupa, Matti; de Mello, Vanessa D; Hanhineva, Kati. 2018. Nutrition and diabetes. 8: 35

Transcriptional effects of cadmium on iron homeostasis differ in calamine accessions of Noccaea caerulescens

Halimaa, P; Blande, D; Baltzi, E; Aarts, MGM; Granlund, L; Keinänen, M; Kärenlampi, SO; Kozhevnikova, AD; Peräniemi, S; Schat, H; Seregin, IV; Tuomainen, M; Tervahauta, AI. 2018. Plant journal. 2019; 97: 306-320

Whole grain intake associated molecule 5-aminovaleric acid betaine decreases ß-oxidation of fatty acids in mouse cardiomyocytes

Kärkkäinen, Olli; Tuomainen, Tomi; Koistinen, Ville; Tuomainen, Marjo; Leppänen, Jukka; Laitinen, Tuomo; Lehtonen, Marko; Rysä, Jaana; Auriola, Seppo; Poso, Antti; Tavi, Pasi; Hanhineva, Kati. 2018. Scientific reports. 8: 13036

Differentially cleaving peptides as a strategy for controlled drug release in human retinal pigment epithelial cells

Bhattacharya M, Sarkhel S, Peltoniemi J, Broadbridge R, Tuomainen M, Auriola S, Urtti A. 2017. Journal of controlled release. 251: 37-48

Impact of Chemical Structure on Conjunctival Drug Permeability: Adopting Porcine Conjunctiva and Cassette Dosing for Construction of In Silico Model

Ramsay E, Ruponen M, Picardat T, Tengvall U, Tuomainen M, Auriola S, Toropainen E, Urtti A, del Amo EM. 2017. Journal of pharmaceutical sciences. 106: 2463-2471

Comparative transcriptome analysis of the metal hyperaccumulator Noccaea caerulescens

Halimaa Pauliina, Blande Daniel, Aarts Mark G M, Tuomainen Marjo, Tervahauta Arja, Kärenlampi Sirpa. 2014. Frontiers in plant science. 5: 1-7

Gene Expression Differences between Noccaea caerulescens Ecotypes Help to Identify Candidate Genes for Metal Phytoremediation

Halimaa Pauliina, Lin Ya-Fen, Ahonen Viivi H, Blande Daniel, Clemens Stephan, Gyenesei Attila, Häikiö Elina, Kärenlampi Sirpa O, Laiho A, Aarts Mark G M, Pursiheimo Juha-Pekka, Schat Henk, Schmidt Holger, Tuomainen Marjo H, Tervahauta Arja I. 2014. Environmental science and technology. 48: 3344-3353

A bisphosphonate increasing the shoot biomass of the metal hyperaccumulator Noccaea caerulescens

Alanne Aino-Liisa, Peräniemi Sirpa, Turhanen Petri, Tuomainen Marjo, Vepsäläinen Jouko, Tervahauta Arja. 2013. Chemosphere. 2014:95: 566-571

Carbohydrate concentrations and freezing stress resistance of silver birch buds grown under elevated temperature and ozone

Riikonen J, Kontunen-Soppela S, Vapaavuori E, Tervahauta A, Tuomainen M, Oksanen E. 2013. Tree physiology. 33: 311-319

Effect of bisphosphonates on metal accumulation in the metal hyperaccumulator plan Noccaea caerulescens

Alanne A, Tuomainen M, Turhanen P, Peräniemi S, Vepsäläinen J, Kärenlmpi S, Tervahauta A. 2013.

Adaptive mechanisms of Noccaea caerulescens ecotypes with contrasting metal hyper-accumulation and hypertolerance traits

Halimaa Pauliina, Ahonen Viivi, Blande Daniel, Clemens Stephan, Gyenesei Attila, Häikiö Elina, Kärenlampi Sirpa, Laiho Asta, Pehkonen Petri, Pursiheimo Juha-Pekka, Schat Henk, Schmidt Holger, Tuomainen Marjo, Tervahauta Arja. 2012.

Needle metabolome, freezing tolerance and gas exchange in Norway spruce seedlings exposed to elevated temperature and ozone concentration

Riikonen Johanna, Kontunen-Soppela Sari, Ossipov Vladimir, Tervahauta Arja, Tuomainen Marjo, Oksanen Elina, Vapaavuori Elina, Heinonen Jaakko, Kivimäenpää Minna. 2012. Tree physiology. 32: 1102-1112

Adaptive mechanisms of hyperaccumulator Noccaea caerulescens ecotypes with contrasting metal hyperaccumulation and hypertolerance traits

Halimaa P, Ahonen V, Gyenesei A, Kärenlampi S, Laiho A, Pehkonen P, Pursiheimo J-P, Schat H, Tuomainen M, Tervahauta A. 2011.

Characterization of the glyoxalase 1 gene TcGLX1 in the metal hyperaccumulator plant Thlaspi caerulescens

Tuomainen Marjo, Ahonen Viivi, Kärenlampi Sirpa O, Schat Henk, Paasela Tanja, Svanys Algirdas, Tuohimetsä Saara, Peräniemi Sirpa, Tervahauta Arja. 2011. Planta. 233: 1173-1184

Metal hyperaccumulator plants: excellent models for metal homeostasis and stress tolerance studies

Tervahauta, A.I., Ahonen, V.H., Halimaa, P.H., Tuomainen, M.H., Kärenlampi, S.O.. 2011.

Next-generation sequencing of metal hyperaccumulator Noccaea caerulescens reveals ecotypic differences in the root transcriptome

Halimaa LP, Ahonen VH, Gyenesei A, Kärenlampi SO, Laiho A, Pehkonen P, Pursiheimo J-P, Schat H, Tuomainen MH, Tervahauta AI. 2011.

Search for molecular mechanisms related to Zn accumulation and tolerance in Thlaspi caerulescens

Tuomainen Marjo. 2011. Publications of the University of Eastern Finland. Dissertations in Forestry and Natural Sciences

Leaf proteome responses of Arabidopsis thaliana exposed to mild cadmium stress

Semane B, Dupae J, Cuypers A, Noben J-P. Tuomainen M, Tervahauta A, Kärenlampi S, Van Belleghem F, Smeets K & Vangronsveld J. 2010. Journal of plant physiology. 167: 247-254

Proteomic study of zinc accumulation and tolerance in metal hyperaccumulator plant Thlaspi caerulescens

Tuomainen M, Tervahauta A, Häyrinen J, Hassinen V, Schat H, Koistinen KM, Lehesranta S, Rantalainen K, Auriola S, Anttonen M & Kärenlampi S. 2010.

Proteomics of Thlaspi caerulescens accessions and an inter-accession cross segregating for zinc accumulation

Tuomainen M, Tervahauta A, Hassinen V, Schat H, Koistinen KM, Lehesranta S, Rantalainen K, Häyrinen J, Auriola S, Anttonen M & Kärenlampi S. 2010. Journal of experimental botany. 61: 1075-1087

Proteomics of Thlaspi caerulescens accessions and inter-accession cross segregating for zinc accumulation

Tuomainen M, Tervahauta A, Häyrinen J, Hassinen V, Schat H, Koistinen K, Lehesranta S, Rantalainen K, Auriola S, Anttonen M & Kärenlampi S. 2010.

Effect of birch (Betula spp.) and associated rhizoidal bacteria on the degradation of soil polyaromatic hydrocarbons, PAH-induced changes in birch proteome and bacterial community

Tervahauta A, Fortelius C, Tuomainen M, Åkerman M-L, Rantalainen K, Sipilä T, Lehesranta SJ, Koistinen KM, Kärenlampi S & Yrjälä K. 2009. Environmental pollution. 157: 341-346

Effect of birch (Betula spp.) and associated rhizoidal bacteria on the degradation of soil polyaromatic hydrocarbons, PAH-induced changes in birch proteome and bacterial community

Tervahauta AI, Fortelius C, Tuomainen M, Åkerman M-L, Rantalainen K, Sipilä T, Lehesranta SJ, Koistinen KM, Kärenlampi S. 2009. Environmental pollution. : 341-346

Metallothioneins 2 and 3 contribute to the metal-adapted phenotype but are not directly linked to Zn accumulation in the metal hyperaccumulator, Thlaspi caerulescens

Hassinen V, Tuomainen M, Peräniemi S, Schat H, Kärenlampi SO & Tervahauta AI. 2009. Journal of experimental botany. 60: 187-196

Multivariate analysis of protein profiles of metal hyperaccumulator Thlaspi caerulescens accessions

Tuomainen MH, Nunan N, Lehesranta SJ, Tervahauta AI, Hassinen VH, Schat H, Koistinen KM, Auriola S, McNicol J, Kärenlampi SO. 2006. Proteomics. 6: 3696-3706

Proteomics of Metal Hyperaccumulator Thlaspi caerulescens

Tuomainen M, Tervahauta A, Koistinen K, Hassinen V, Kärenlampi S. Teoksessa: G. R. Gobran and N. Lepp(toim.) , 2003. Conference Proceedings, 7th International Conference on the Biogeochemistry of Trace Elements. s. 112-113. Swedish University of Agricultural Sciences

Tarkenna hakuasi

Projektit

Julkaisut

Cold-stimulated brown adipose tissue activation is related to changes in serum metabolites relevant to NAD+ metabolism in humans

Topical pharmacokinetics of dexamethasone suspensions in the rabbit eye: Bioavailability comparison

Understanding dexamethasone kinetics in the rabbit tear fluid: Drug release and clearance from solution, suspension and hydrogel formulations

Indole-3-Propionic Acid, a Gut-Derived Tryptophan Metabolite, Associates with Hepatic Fibrosis

"notame": Workflow for Non-Targeted LC-MS Metabolic Profiling

Side-stream products of malting: a neglected source of phytochemicals

Quantitative assessment of betainized compounds and associations with dietary and metabolic biomarkers in the randomized study of the healthy Nordic diet (SYSDIET)

Associations of serum indolepropionic acid, a gut microbiota metabolite, with type 2 diabetes and low-grade inflammation in high-risk individuals

Transcriptional effects of cadmium on iron homeostasis differ in calamine accessions of Noccaea caerulescens

Whole grain intake associated molecule 5-aminovaleric acid betaine decreases ß-oxidation of fatty acids in mouse cardiomyocytes

Differentially cleaving peptides as a strategy for controlled drug release in human retinal pigment epithelial cells

Impact of Chemical Structure on Conjunctival Drug Permeability: Adopting Porcine Conjunctiva and Cassette Dosing for Construction of In Silico Model

Comparative transcriptome analysis of the metal hyperaccumulator Noccaea caerulescens

Gene Expression Differences between Noccaea caerulescens Ecotypes Help to Identify Candidate Genes for Metal Phytoremediation

A bisphosphonate increasing the shoot biomass of the metal hyperaccumulator Noccaea caerulescens

Carbohydrate concentrations and freezing stress resistance of silver birch buds grown under elevated temperature and ozone

Effect of bisphosphonates on metal accumulation in the metal hyperaccumulator plan Noccaea caerulescens

Adaptive mechanisms of Noccaea caerulescens ecotypes with contrasting metal hyper-accumulation and hypertolerance traits

Needle metabolome, freezing tolerance and gas exchange in Norway spruce seedlings exposed to elevated temperature and ozone concentration

Adaptive mechanisms of hyperaccumulator Noccaea caerulescens ecotypes with contrasting metal hyperaccumulation and hypertolerance traits

Characterization of the glyoxalase 1 gene TcGLX1 in the metal hyperaccumulator plant Thlaspi caerulescens

Metal hyperaccumulator plants: excellent models for metal homeostasis and stress tolerance studies

Next-generation sequencing of metal hyperaccumulator Noccaea caerulescens reveals ecotypic differences in the root transcriptome

Search for molecular mechanisms related to Zn accumulation and tolerance in Thlaspi caerulescens

Leaf proteome responses of Arabidopsis thaliana exposed to mild cadmium stress

Proteomic study of zinc accumulation and tolerance in metal hyperaccumulator plant Thlaspi caerulescens

Proteomics of Thlaspi caerulescens accessions and an inter-accession cross segregating for zinc accumulation

Proteomics of Thlaspi caerulescens accessions and inter-accession cross segregating for zinc accumulation

Effect of birch (Betula spp.) and associated rhizoidal bacteria on the degradation of soil polyaromatic hydrocarbons, PAH-induced changes in birch proteome and bacterial community

Effect of birch (Betula spp.) and associated rhizoidal bacteria on the degradation of soil polyaromatic hydrocarbons, PAH-induced changes in birch proteome and bacterial community

Metallothioneins 2 and 3 contribute to the metal-adapted phenotype but are not directly linked to Zn accumulation in the metal hyperaccumulator, Thlaspi caerulescens

Multivariate analysis of protein profiles of metal hyperaccumulator Thlaspi caerulescens accessions

Proteomics of Metal Hyperaccumulator Thlaspi caerulescens