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Muistin neurobiologia 12.11.2022 -

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Most dystrophic neurites in the common 5xFAD Alzheimer mouse model originate from axon terminals
Mabrouk, R; Miettinen, PO; Tanila, H. 2023. Neurobiology of disease. 182:
Diabetic phenotype in mouse and humans reduces the number of microglia around ß-amyloid plaques
Natunen, Teemu; Martiskainen, Henna; Marttinen, Mikael; Gabbouj, Sami; Koivisto, Hennariikka; Kemppainen, Susanna; Kaipainen, Satu; Takalo, Mari; Svobodová, Helena; Leppänen, Luukas; Kemiläinen, Benjam; Ryhänen, Simo; Kuulasmaa, Teemu: Rahunen, Eija: Juutinen, Sisko; Mäkinen, Petra; Miettinen, Pasi; Rauramaa, Tuomas; Pihlajamäki, Jussi; Haapasalo, Annakaisa; et al [incl. Leinonen, Ville; Tanila, Heikki; Hiltunen, Mikko]. 2020. Molecular neurodegeneration. 15: 66
Elevated Age-Related Cortical Iron, Ferritin and Amyloid Plaques in APP(swe)/PS1(Delta E9) Transgenic Mouse Model of Alzheimer's Disease
Svobodova, H; Kosn, D; Balazsiova, Z; Tanila, H; Miettinen, P O; Sierra, A; Vitovic, P; Wagner, A; Polak, S; Kopani, M. 2019. Physiological research. 68: S445-S451
Null mutation in P4h-tm leads to decreased fear and anxiety and increased social behavior in mice
Leinonen, H; Koivisto, H; Lipponen, HR; Matilainen, A; Salo, AM; Dimova, EY; Hämäläinen, E; Stavén, S; Miettinen, P; Myllyharju, J; Koivunen, P; Tanila, H. 2019. Neuropharmacology. 153: 63-72
Progressive age-dependent motor impairment in human tau P301S overexpressing mice
Koivisto, H; Ytebrouck, E; Carmans, S; Naderi, R; Miettinen, PO; Roucourt, B; Tanila, H. 2019. Behavioural brain research. 376: 112158
Brain-Specific Basal and Novelty-Induced Alternations in PI3K-Akt and MAPK/ERK Signaling in a Middle-Aged AßPP/PS1 Mouse Model of Alzheimer's Disease
Guillot Florence, Kemppainen Susanna, Lavasseur Gregoire, Miettinen Pasi O, Laroche Serge, Tanila Heikki, Davis Sabrina. 2016. Journal of Alzheimer's disease. 51: 1157-1173
Opposing effects of APP/PS1 and TrkB.T1 genotypes on midbrain dopamine neurons and stimulated dopamine release in vivo
Kärkkäinen Elisa, Yavich Leonid, Miettinen Pasi O, Tanila Heikki. 2015. Brain research. 1622: 452-465
Relationship between ubiquilin-1 and BACE1 in human Alzheimer's disease and APdE9 transgenic mouse brain and cell-based models
Natunen Teemu, Takalo Mari, Kemppainen Ssusanna, Leskelä Stina, Marttinen Mikael, Kurkinen Kaisa MA, Pursiheimo Juha-Pekka, Sarajärvi Timo, Viswanathan Jayashree, Gabbouj Sami, Solje Eino, Tahvanainen Eveliina, Pirttimäki Tiina, Kurki Mitja, Paananen Jussi, Rauramaa Tuomas, Miettinen Pasi, Mäkinen Petra, Leinonen Ville, Soininen Hilkka et al. 2015. Neurobiology of disease. 2016; 85: 187-205
Axonal tract tracing for delineating interacting brain regions: Implications for Alzheimer's disease-associated memory
van Groen T, Miettinen P, Kadish I. 2014. Future neurology. Volume 9, Issue 1: 89-98
Behavioral and neuropathological consequences of transient global ischemia in APP/PS1 Alzheimer model mice
Kemppainen S, Hämäläinen E, Miettinen PO, Koistinaho J, Tanila H. 2014. Behavioural brain research. Volume 275, 15 December 2014: 15-26
High-fat diet increases tau expression in the brain of T2DM and AD mice independently of peripheral metabolic status
Takalo M, Haapasalo A, Martiskainen H, Kurkinen KM, Koivisto H, Miettinen P, Khandelwal VK, Kemppainen S, Kaminska D, Mäkinen P, Leinonen V, Pihlajamäki J, Soininen H, Laakso M, Tanila H, Hiltunen M. 2014. Journal of nutritional biochemistry. 25: 634-641
Special lipid-based diets alleviate cognitive deficits in the APPswe/PS1dE9 transgenic mouse model of Alzheimer's disease independent of brain amyloid deposition
Koivisto H, Grimm MO, Rothhaar TL, Berkecz R, Lütjohann D D, Giniatullina R, Takalo M, Miettinen PO, Lahtinen HM, Giniatullin R, Penke B, Janáky T, Broersen LM, Hartmann T, Tanila H. 2014. Journal of nutritional biochemistry. 25: 157-169
The Impact of Bdnf Gene Deficiency to the Memory Impairment and Brain Pathology of APPswe/PS1dE9 Mouse Model of Alzheimer's Disease
Rantamäki T, Kemppainen S, Autio H, Stavén S, Koivisto H, Kojima M, Antila H, Miettinen PO, Kärkkäinen E, Karpova N, Vesa L, Lindemann L, Hoener MC, Tanila H, Castrén E. 2013. PLoS ONE. 2013 Jul 3;8(7): e68722: -
Contribution of genetic and dietary insulin resistance to Alzheimer phenotype in APP/PS1 transgenic mice
Hiltunen M, Khandelwal VKM, Yaluri N, Tiilikainen T, Tusa M, Koivisto H, Krzisch M, Vepsäläinen S, Mäkinen P, Kemppainen S, Miettinen P, Haapasalo A, Soininen H, Laakso M, Tanila H. 2012. Journal of cellular and molecular medicine. 16: 1206-1222
Transduced Wild-Type but Not P301S Mutated Human Tau Shows Hyperphosphorylation in Transgenic Mice Overexpressing A30P Mutated Human Alpha-Synuclein
Oksman M, Wisman LA, Jiang H, Miettinen P, Kirik D, Tanila H. 2012. Neurodegenerative diseases. 2012 Aug 30. [Epub ahead of print]: - -
The entorhinal cortex of the mouse: Organization of the projection to the hippocampal formation
van Groen T, Miettinen P, Kadish I. 2003. Hippocampus. 13: 133-149