VANESSA DE MELLO LAAKSONEN

Yhteystiedot

PROJEKTIT - UEF

• 
  Nutrigenomiikan

Linkit

• Research gate https://www.researchgate.net/profile/Vanessa_Mello

Julkaisut

• Murphy, Rachel A; Tintle, Nathan; Harris, William S; Darvishian, Maryam; Marklund, Matti; Virtanen, Jyrki K; Hantunen, Sari; de Mello, Vanessa D; Tuomilehto, Jaakko; Lindström, Jaana; Bolt, Matthew A; Brouwer, Ingeborg A; Wood, Alexis C; Senn, Mackenzie; Redline, Susan; Tsai, Michael Y; Gudnason, Vilmundur; Eiriksdottir, Gudny; Lindberg, Eva; Shadyab, Aladdin H et al [incl. Uusitupa, Matti]. 2022. Omega-3 and omega-6 polyunsaturated fatty acid biomarkers and sleep: a pooled analysis of cohort studies On behalf of the Fatty Acids and Outcomes Research Consortium (FORCE) American journal of clinical nutrition 115 3: 864-876. 2022
• Sehgal, Ratika Ilha, Mariana Vaittinen, Maija Kaminska, Dorota Männistö, Ville Kärjä, Vesa Tuomainen, Marjo Hanhineva, Kati Romeo, Stefano Pajukanta, Päivi Pihlajamäki, Jussi de Mello, Vanessa D.. 2021. Indole-3-Propionic Acid, a Gut-Derived Tryptophan Metabolite, Associates with Hepatic Fibrosis Nutrients 13 10: 3509. 2021
• de Mello, Vanessa Derenji; Selander, Tuomas; Lindström, Jaana; Tuomilehto, Jaakko; Uusitupa, Matti; Kaarniranta, Kai. 2021. Serum Levels of Plasmalogens and Fatty Acid Metabolites Associate with Retinal Microangiopathy in Participants from the Finnish Diabetes Prevention Study Nutrients 13 12: 4452. 2021
• Lankinen, MA; de Mello, VD; Meuronen, T; Sallinen, T; Ågren, J; Virtanen, KA; Laakso, M; Pihlajamäki, J; Schwab, U. 2021. The FADS1 Genotype Modifes Metabolic Responses to the Linoleic Acid and Alpha-linolenic Acid Containing Plant Oils-Genotype Based Randomized Trial FADSDIET2 Molecular nutrition and food research 65 7: 2001004. 2021
• de Mello, Vanessa D; Sehgal, Ratika; Männistö, Ville; Klåvus, Anton; Nilsson, Emma; Perfilyev, Alexander; Kaminska, Dorota; Miao, Zong; Pajukanta, Päivi; Ling, Charlotte; Hanhineva, Kati; Pihlajamäki, Jussi. 2020. Serum aromatic and branched-chain amino acids associated with NASH demonstrate divergent associations with serum lipids Liver international 2021; 41 4: 754-763. 2020
• Meuronen, Topi; Lankinen, Maria A; Fauland, Alexander; Shimizu, Bun-Ichi; de Mello, Vanessa D; Laaksonen, David E; Wheelock, Craig E; Erkkilä, Arja T; Schwab, Ursula S. 2020. Intake of Camelina Sativa Oil and Fatty Fish Alter the Plasma Lipid Mediator Profile in Subjects with Impaired Glucose Metabolism - A Randomized Controlled Trial Prostaglandins leukotrienes and essential fatty acids 159: 102143. 2020
• Sousa, Danilo Ferreira de; Araújo, Márcio Flávio Moura de; de Mello, Vanessa Derenji; Damasceno, Marta Maria Coelho; Freitas, Roberto Wagner Júnior Freire de. 2020. Cost-Effectiveness of Passion Fruit Albedo versus Turmeric in the Glycemic and Lipaemic Control of People with Type 2 Diabetes: Randomized Clinical Trial Journal of the american college of nutrition 2021; 40 8: 679-688. 2020
• de Mello, VD; Dahlman, I; Lankinen, M; Kurl, S; Pitkänen, L; Laaksonen, DE; Schwab, US; Erkkilä, AT. 2019. The effect of different sources of fish and camelina sativa oil on immune cell and adipose tissue mRNA expression in subjects with abnormal fasting glucose metabolism: a randomized controlled trial Nutrition and diabetes 9 1: 1. 2019
• Erkkilä, AT; Lee, JC; Lankinen, M; Manninen, S; Leung ,HH; Oger, C; de Mello, VD; Schwab, US. 2019. Camelina sativa Oil, Fatty Fish, and Lean Fish Do Not Markedly Affect Urinary Prostanoids in Subjects with Impaired Glucose Metabolism Lipids 54 8: 453-464. 2019
• Myhrstad, MC; de Mello, VD; Dahlman, I; Kolehmainen, M; Paananen, J; Rundblad, A; Carlberg, C; Olstad, OK; Pihlajamäki, J; Holven, KB; Hermansen, K; Dragsted, LO; Gunnarsdottir, I; Cloetens, L; Storm, MU; Åkesson, B; Rosqvist, F; Hukkanen, J; et al. (incl. Schwab, U; Uusitupa, M). 2019. Healthy Nordic Diet Modulates the Expression of Genes Related to Mitochondrial Function and Immune Response in Peripheral Blood Mononuclear Cells from Subjects with the Metabolic Syndrome - A SYSDIET Sub-Study Molecular nutrition and food research 63 13: 1801405. 2019
• Männistö, V; Kaminska, D; Kärjä, V; Tiainen, M; de Mello, VD; Hanhineva, K; Soininen, P; Ala-Korpela, M; Pihlajamäki, J. 2019. Total liver phosphatidylcholine content associates with non-alcoholic steatohepatitis and glycine N-methyltransferase expression Liver international 39 10: 1895-1905. 2019
• Ulven, SM; Holven, KB; Rundblad, A; Myhrstad, MCW; Leder, L; Dahlman, I; Mello, VD; Schwab, U; Carlberg, C; Pihlajamäki, J; Hermansen, K; Dragsted, LO; Gunnarsdottir, I; Cloetens, L; Åkesson, B; Rosqvist, F; Hukkanen, J; Herzig, KH; Savolainen, MJ; Risérus, U; et al. [incl. Uusitupa, M]. 2019. An Isocaloric Nordic Diet Modulates RELA and TNFRSF1A Gene Expression in Peripheral Blood Mononuclear Cells in Individuals with Metabolic Syndrome-A SYSDIET Sub-Study Nutrients 11 12: 2932. 2019
• Walle, P; Männistö, V; de Mello, VD; Vaittinen, M; Perfilyev, A; Hanhineva, K; Ling, C; Pihlajamäki, J. 2019. Liver DNA methylation of FADS2 associates with FADS2 genotypex Clinical epigenetics 11 1: 10. 2019
• Tuomainen, Marjo; Lindström, Jaana; Lehtonen, Marko; Auriola, Seppo; Pihlajamäki, Jussi; Peltonen, Markku; Tuomilehto, Jaakko; Uusitupa, Matti; de Mello, Vanessa D; Hanhineva, Kati. 2018. Associations of serum indolepropionic acid, a gut microbiota metabolite, with type 2 diabetes and low-grade inflammation in high-risk individuals Nutrition and diabetes 8: 35. 2018
• Schwab, US; Lankinen, MA; de Mello, VD; Manninen, SM; Kurl, S; Pulkki, KJ; Laaksonen, DE; Erkkilä, AT. 2018. Camelina Sativa Oil, but not Fatty Fish or Lean Fish Improved Serum Lipid Profile in Subjects with Impaired Glucose Metabolism - a Randomized Controlled Trial Molecular nutrition and food research 62 4: 1700503. 2018
• Manninen, Suvi M; Lankinen, Maria A; de Mello, Vanessa D; Laaksonen, David E; Schwab, Ursula S; Erkkilä, Arja T. 2018. Intake of Fatty Fish Alters the Size and the Concentration of Lipid Components of HDL Particles and Camelina Sativa Oil Decreases IDL Particle Concentration in Subjects with Impaired Glucose Metabolism. Molecular Nutrition & Food Research 62 10: 1701042. 2018
• García-Calzón, Sonia; Perfilyev, Alexander; de Mello, Vanessa D; Pihlajamäki, Jussi; Ling, Charlotte. 2018. Sex Differences in the Methylome and Transcriptome of the Human Liver and Circulating HDL-Cholesterol Levels Journal of clinical endocrinology and metabolism 103 12: 4395-4408. 2018
• Aregbesola, A; de Mello, VDF; Lindström, J; Voutilainen, S; Virtanen, JK; Keinänen-Kiukaanniemi, S; Tuomainen, TP; Tuomilehto, J; Uusitupa, M. 2018. Serum Adiponectin/Ferritin Ratio in Relation to the Risk of Type 2 diabetes and Insulin Sensitivity. DIABETES RESEARCH AND CLINICAL PRACTICE 141: 264-274. 2018
• Manninen, S; Lankinen, M; de Mello, V; Ågren, J; Laaksonen, D; Schwab, U; Erkkilä, A. 2018. The effect of camelina sativa oil and fish intakes on fatty acid compositions of blood lipid fractions NUTRITION, METABOLISM AND CARDIOVASCULAR DISEASES 2019; 29 1: 51-61. 2018
• de Mello VD, Lankinen MA, Lindström J, Puupponen-Pimiä R, Laaksonen DE, Pihlajamäki J, Lehtonen M, Uusitupa M, Tuomilehto J, Kolehmainen M, Törrönen R, Hanhineva K. 2017. Fasting serum hippuric acid is elevated after bilberry (Vaccinium myrtillus) consumption and associates with improvement of fasting glucose levels and insulin secretion in persons at high risk of developing type 2 diabetes. Molecular Nutrition & Food Research 61 9: 1700019. 2017
• de Mello VD, Paananen J, Lindstrom J, Lankinen MA, Shi L, Kuusisto J, Pihlajamaki J, Auriola S, Lehtonen M, Rolandsson O, Bergdahl IA, Nordin E, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Landberg R, Eriksson JG, Tuomilehto J, Hanhineva K, Uusitupa M. 2017. Indolepropionic acid and novel lipid metabolites are associated with a lower risk of type 2 diabetes in the Finnish Diabetes Prevention Study. Scientific Reports 7: 46337. 2017
• García-Calzón Sonia, Perfilyev Alexander, Männistö Ville, de Mello Vanessa D, Nilsson Emma, Pihlajamäki Jussi, Ling Charlotte. 2017. Diabetes medication associates with DNA methylation of metformin transporter genes in the human liver. Clinical Epigenetics 9: 102. 2017
• Bysani M, Perfilyev A, de Mello VD, Rönn T, Nilsson E, Pihlajamäki J, Ling C. 2016. Epigenetic alterations in blood mirror age-associated DNA methylation and gene expression changes in human liver. Epigenomics 2017; 9 2: 105-122. 2016
• Dayeh T, Tuomi T, Almgren P, Perfilyev A, Jansson PA, de Mello VD, Pihlajamäki J, Vaag A, Groop L, Nilsson E, Ling C. 2016. DNA methylation of loci within ABCG1 and PHOSPHO1 in blood DNA is associated with future type 2 diabetes risk. Epigenetics 11 7: 482-488. 2016
• Leder Lena, Kolehmainen Marjukka, Narverud Ingunn, Dahlman Ingrid, Myhrstad Mari CW, de Mello Vanessa D, Paananen Jussi, Carlberg Castren, Schwab Ursula, Herzig Karl-Heinz, Cloetens Lieselotte, Storm Matilda Ulmius, Hukkanen Janne, Savolainen Markku J, Rosqvist Fredrik, Hermansen Kjeld, Dragsted Lars O, Gunnarsdottir Ingibjörk, Thorsdottir Inga, Risérus Ulf et al.. 2016. Effects of a healthy Nordic diet on gene expression changes in peripheral blood mononuclear cells in response to an oral glucose tolerance test in subjects with metabolic syndrome: a SYSDIET sub-study. Genes and Nutrition 11 3: 1-13. 2016
• Tovar Juscelino, de Mello Vanessa D, Nilsson Anne, Johansson Maria, Paananen Jussi, Lehtonen Marko, Hanhineva Kati, Björck Inger. 2016. Reduction in cardiometabolic risk factors by a multifunctional diet is mediated via several branches of metabolism as evidenced by non-targeted metabolite profiling approach. Molecular Nutrition & Food Research [Epub ahead of print 8 Nov 2016]: 1-12. 2016
• Venäläinen Taisa M, Viitasalo Anna M, Schwab Ursula S, Eloranta Aino-Maija, Haapala Eero A, Jalkanen Henna P, de Mello Vanessa DF, Laaksonen David E, Lindi Virpi I, Ågren Jyrki J, Lakka Timo A. 2016. Effect of a 2-y dietary and physical activity intervention on plasma fatty acid composition and estimated desaturase and elongase activities in children: the Physical Activity and Nutrition in Children Study. AMERICAN JOURNAL OF CLINICAL NUTRITION 104 4: 964-972. 2016
• Takkunen Markus J, de Mello Vanessa D, Schwab Ursula S, Kuusisto Johanna, Vaittinen Maija, Ågren Jyrki J, Laakso Markku, Pihlajamäki Jussi, Uusitupa MI. 2015. Gene-diet interaction of a common FADS1 variant with marine polyunsaturated fatty acids for fatty acid composition in plasma and erythrocytes among men. Molecular Nutrition & Food Research 2016; 60 2: 381-389. 2015
• Takkunen Markus J, Schwab Ursula S, de Mello Vanessa DF, Eriksson Johan G, Lindström Jaana, Tuomilehto Jaakko, Uusitupa Matti IJ, the DPS Study Group. 2015. Longitudinal associations of serum fatty acid composition with type 2 diabetes risk and markers of insulin secretion and sensitivity in the Finnish Diabetes Prevention Study. EUROPEAN JOURNAL OF NUTRITION 2016; 55 3: 967-979. 2015
• Nilsson Emma, Matte Ashok, Perfilyev Alexander, de Mello Vanessa D, Käkelä Pirjo, Pihlajamäki Jussi, Ling Charlotte. 2015. Epigenetic alterations in human liver from subjects with type 2 diabetes in parallel with reduced folate levels. JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM [epub ahead of p rint Sep 29, 2015]: -. 2015
• de Mello VDF, Lindström J, Eriksson JG, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Pihlajamäki J, Tuomilehto J, Uusitupa M. 2015. Markers of cholesterol metabolism as biomarkers in predicting diabetes in the Finnish Diabetes Prevention Study. NUTRITION, METABOLISM AND CARDIOVASCULAR DISEASES 25 7: 635-642. 2015
• de Mello Vanessa Derenji Ferreira, Pulkkinen Leena, Lalli Marianne, Kolehmainen Marjukka, Pihlajamäki Jussi, Uusitupa Matti. 2014. DNA methylation in obesity and type 2 diabetes. Annals of Medicine 46: 103-113. 2014
• Venäläinen Taisa, Schwab Ursula, Ågren Jyrki, de Mello Vanessa, Lindi Virpi, Eloranta Aino-Maija, Kiiskinen Sanna, Laaksonen David, Lakka Timo A. 2014. Cross-Sectional Associations of Food Consumption with Plasma Fatty Acid Composition and Estimated Desaturase Activities in Finnish Children. LIPIDS 49 5: 467-479. 2014
• Erkkilä AT, Schwab US, Lehto S, de Mello VD, Kangas AJ, Soininen P, Ala-Korpela M, Uusitupa MIJ. 2013. Effect of fatty and lean fish intake on lipoprotein subclasses in subjects with coronary heart disease: A controlled trial. Journal of Clinical Lipidology online [Epub ahead of print]: -. 2013
• Hovatta I, de Mello VDF, Kananen L, Lindström J, Eriksson JG, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Peltonen M, Tuomilehto J, Uusitupa M. 2012. Leukocyte Telomere Lenght in the Finnish Diabetes Prevention Study. PLOS ONE [ONLINE] 7 4: 1-6. 2012
• de Mello VDF, Kolehmainen M, Schwab U, Pulkkinen L, Uusitupa M. 2012. Gene expression of peripheral blood mononuclear cells as a tool in dietary intervention studies: What do we know so far?. Molecular Nutrition & Food Research 56: 1160-1172. 2012
• de Mello Laaksonen VD, Lindström J, Eriksson J, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Sundvall J, Laakso M, Tuomilehto J, Uusitupa M. 2012. Insulin secretion and its determinants in the progression of impaired glucose tolerance to type 2 diabetes in impaired glucose-tolerant individuals: the finnish diabetes prevention study DIABETES CARE 35: 211-217. 2012
• de Mello Vanessa D, Schwab Ursula, Kolehmainen Marjukka, Koenig W, Siloaho Maritta, Poutanen Kaisa, Mykkänen Hannu, Uusitupa Matti. 2011. A diet high in fatty fish, bilberries and wholegrain products improves markers of endothelial function and inflammation in individuals with impaired glucose metabolism in a randomised controlled trial: The Sysdimet study. DIABETOLOGIA 54: 2755-2767. 2011
• De Mello VDF, Erkkilä AT, Schwab US, Pulkkinen L, Kolehmainen M, Atalay M, Mussalo H, Lankinen M, Oresic M, Lehto S, Uusitupa M, De Mello VDF, Schwab US, Pulkkinen L, Kolehmainen M, Lankinen M, Uusitupa M. 2009. The effect of fatty or lean fish intake on inflammatory gene expression in peripheral blood mononuclear cells of patients with coronary heart disease. EUROPEAN JOURNAL OF NUTRITION 48: 447-455. 2009
• De Mello VDF, Lankinen M, Schwab U, Kolehmainen M, Lehto S, Seppä-Laakso T, Oresic M, Pulkkinen L, Uusitupa M, Erkkilä AT, De Mello VDF, Lankinen M, Schwab U, Kolehmainen M, Pulkkinen L, Uusitupa M. 2009. Link between plasma ceramides, inflammation and insulin resistance: association with serum IL-6 concentration in patients with coronary heart disease. DIABETOLOGIA 52: 2612-2615. 2009
• De Mello V, Kolehmainen M, Pulkkinen L, Schwab U, Mager U, Laaksonen DE, Niskanen L, Gylling H, Atalay M, Rauramaa R, Uusitupa M, De Mello V, Kolehmainen M, Pulkkinen L, Schwab U, Mager U, Gylling H, Uusitupa M. 2008. Downregulation of genes involved in NFkappaB activation in peripheral blood mononuclear cells after weight loss is associated with the improvement of insulin sensitivity in individuals with the metabolic syndrome: the GENOBIN study. DIABETOLOGIA 51: 2060-2067. 2008
• de Mello VDF, Kolehmainen M, Schwab U, Mager U, Laaksonen DE, Pulkkinen L, Niskanen L, Gylling H, Atalay M, Rauramaa R, Uusitupa M, Ferreira de Mello V, Kolehmainen M, Schwab U, Mager U, Pulkkinen L, Gylling H, Uusitupa M. 2008. Effect of weight loss on cytokine messenger RNA expression in peripheral blood mononuclear cells of obese subjects with the metabolic syndrome. METABOLISM: CLINICAL AND EXPERIMENTAL 57: 192-199. 2008
• Erkkilä A, de Mello VDF, Risérus U, Laaksonen DE. 2008. Dietary fatty acids and cardiovascular disease: an epidemiological approach. PROGRESS IN LIPID RESEARCH 47: 172-187. 2008