Cerebrovascular Disorders and Stroke Recovery

Sulje

Tarkenna hakuasi

Tutkimusryhmä

01.01.2022 -

Kliinisen lääketieteen yksikkö, Lääketieteen laitos, Terveystieteiden tiedekunta

Tiedot Ihmiset Julkaisut

Johtajat

Pekka Jäkälä

Professori

Kliinisen lääketieteen yksikkö, Lääketieteen laitos, Terveystieteiden tiedekunta
Jukka Jolkkonen

Tutkimusjohtaja

Biolääketieteen yksikkö, Lääketieteen laitos, Terveystieteiden tiedekunta

AVH-tutkimus perustuu vahvaan translationaaliseen yhteistyöhön. Tavoitteena on kehittää turvallisia ja tehokkaita hoitoja aivoverenkiertohäiriöistä kärsivien potilaiden auttamiseksi.

Lisätietoja tutkimusryhmästä voi lukea englanninkieliseltä sivulta.

Yhteistyö

SECRETO (Searching for Explanations for Cryptogenic Stroke in the Young)
- Adjunct Prof. Jukka Putaala, University Hospital of Helsinki, Finland
- Prof. Risto Roine, University Hospital of Turku, Finland
- Adjunct Prof. Heikki Numminen, University Hospital of Tampere, Finland
- Adjunct Prof. Juha Huhtakangas, University Hospital of Oulu, Finland
Mechanisms and Imaging of Cardiogenic Embolism
- Adjunt Prof. Pirjo Mustonen, Department of Cardiology, Jyväskylä Central Hospital
- Prof. Ritva Vanninen, Department of Radiology, Kuopio University Hospital
Cost-Effectiveness of Invasive Stroke Treatments
- Adjunct Prof. Stepani Bendel, Intensive Care Unit, Kuopio University Hospital
Clinical Neurorehabilitation
- Dr. Kauko Pitkänen, VetreaNeuron, Kuopio, Finland
- Dr. Sinikka Hiekkala, PT, PhD, The Finnish Association of People with Physical Disabilities, Lahti, Finland
- Prof. Pasi Karjalainen, Department of Physics, UEF
Translational Studies
- Prof. Tarja Malm, A.I.Virtanen Institute for Molecular Sciences, University of Eastern Finland
- Prof. Chuansheng Zhao, Professor, Neurology Department The First Hospital of China Medical University, Shenyang, China

Avainsanat

aivoverenkiertohäiriöt akuuttihoito ennaltaehkäisy kliininen lääketiede kuntoutus liuotushoito mekaaninen tromboektomia neurologia tehohoito translationaalinen tutkimus

Tarkenna hakuasi

Cerebrovascular Disorders and Stroke Recovery

Johtajat

Pekka Jäkälä

Jukka Jolkkonen

Yhteistyö

Yhteistyökumppanit

Avainsanat

Johtajat

Pekka Jäkälä

Jukka Jolkkonen

Muut ryhmän jäsenet

Acute stroke and TIA patients have specific polygraphic features of obstructive sleep apnea

Association between migraine and cryptogenic ischemic stroke in young adults

Blood-based Biomarkers and Stem Cell Therapy in Human Stroke: A Systematic Review

Communications Between Peripheral and the Brain-Resident Immune System in Neuronal Regeneration After Stroke

Hypoxia and extracellular vesicles: A review on methods, vesicular cargo and functions

Increased migratory and homing abilities of neural and mesenchymal stem cell populations by transient cell modifications: Preclinical progress and clinical relevance

Neurorepair Strategies After Stroke

Neurotropism of SARS-CoV-2 and its neuropathological alterations: Similarities with other coronaviruses

Tau, S100B and NSE as Blood Biomarkers in Acute Cerebrovascular Events

The Selection of an Optimal Transportation Strategy in Urgent Stroke Missions: A Simulation Study

An injectable implant to stimulate the sphenopalatine ganglion for treatment of acute ischaemic stroke up to 24 h from onset (ImpACT-24B): an international, randomised, double-blind, sham-controlled, pivotal trial

Combined Adipose Tissue-Derived Mesenchymal Stem Cell Therapy and Rehabilitation in Experimental Stroke

Effects of CXCR7-neutralizing antibody on neurogenesis in the hippocampal dentate gyrus and cognitive function in the chronic phase of cerebral ischemia

Intravenous delivery of adipose tissue-derived mesenchymal stem cells improves brain repair in hyperglycemic stroke rats

Mesenchymal Stem Cells From Adipose Tissue Do not Improve Functional Recovery After Ischemic Stroke in Hypertensive Rats

Serum Neurofilament Light Chain Concentration Correlates with Infarct Volume but Not Prognosis in Acute Ischemic Stroke

Stem Cells as an Emerging Paradigm in Stroke 4: Advancing and Accelerating Preclinical Research

Behavioral outcome measures to improve experimental stroke research

Future of Animal Modeling for Poststroke Tissue Repair

Intravascular cell therapy in stroke: predicting the future trends

Mechanical Thrombectomy of Large Artery Occlusion Is Beneficial in Octogenarians

Translating experimental evidence to finding novel ways to promote motor recovery in stroke patients - a review

Aivoverenkiertohäiriöt ja diabetes - mitä uutta?

Concise Review: Increasing the Validity of Cerebrovascular Disease Models and Experimental Methods for Translational Stem Cell Research

Enhancing the Alignment of the Preclinical and Clinical Stroke Recovery Research Pipeline: Consensus-Based Core Recommendations From the Stroke Recovery and Rehabilitation Roundtable Translational Working Group

Inhibition of Nkcc1 Promotes Axonal Growth and Motor Recovery in Ischemic Rats

Soluble Urokinase-type Plasminogen Activator Receptor Predicts All-cause 5-Year Mortality in Ischemic Stroke and TIA

vWF correlates with visceral and pericardial adipose tissue in patients with a recent stroke of suspected cardiogenic etiology

Cardiac CT Differentiates Left Atrial Appendage Thrombi from Circulatory Stasis in Acute Stroke Patients

Chloride Co-transporter NKCC1 Inhibitor Bumetanide Enhances Neurogenesis and Behavioral Recovery in Rats After Experimental Stroke

Functional and structural cortical characteristics after restricted focal motor cortical infarction evaluated at chronic stage : Indications from a preliminary study

Increased protein expression levels of pCREB, BDNF and SDF-1/CXCR4 in the hippocampus may be associated with enhanced neurogenesis induced by environmental enrichment

Longitudinal study on modulated corticospinal excitability throughout recovery in supratentorial stroke

The Current State of Cell Therapies for Cerebrovascular Diseases

Translational Hurdles in Stroke Recovery Studies

Acute Phase IL-10 Plasma Concentration Associates with the High Risk Sources of Cardiogenic Stroke

CXCR4 antagonist AMD3100 reverses the neurogenesis and behavioral recovery promoted by forced limb-use in stroke rats

Combined enriched environment/atipamezole treatment transiently improves sensory functions in stroke rats independent from neurogenesis and angiogenesis

Diagnostic Performance of Left Atrial Diameter Measurement in Computed Tomography to Detect Increased Left Atrial Volume

Fluoxetine Enhances Neurogenesis in Aged Rats with Cortical Infarcts, but This is not Reflected in a Behavioral Recovery

Increased Visceral Adipose Tissue as a Potential Risk Factor in Patients with Embolic Stroke of Undetermined Source (ESUS)

Infarction of the Corpus Callosum : A Retrospective Clinical Investigation

Left Atrial Appendage Morphology in Patients with Suspected Cardiogenic Stroke without Known Atrial Fibrillation

Proper housing conditions in experimental stroke studies - special emphasis on environmental enrichment

The cerebral embolism evoked by intra-arterial delivery of allogeneic bone marrow mesenchymal stem cells in rats is related to cell dose and infusion velocity

The dark side of the force - constraints and complications of cell therapies for stroke

The future of stem cell therapy for stroke rehabilitation

Unexpected complication in a rat stroke model: exacerbation of secondary pathology in the thalamus by subacute intraarterial administration of human bone marrow-derived mesenchymal stem cells

Determinants of left atrial appendage volume in stroke patients without chronic atrial fibrillation

Differential Clearance of Rat and Human Bone Marrow-Derived Mesenchymal Stem Cells from the Brain After Intra-arterial Infusion in Rats

Forced limb-use enhanced neurogenesis and behavioral recovery after stroke in the aged rats

Morphological and volumetric analysis of left atrial appendage and left atrium: cardiac computed tomography-based reproducibility assessment

Computed tomography and echocardiography together reveal more high-risk findings than echocardiography alone in the diagnostics of stroke etiology

Effect of middle cerebral artery territory ischemic stroke on QT interval

Left atrial appendage volume increased in more than half of patients with cryptogenic stroke

Time for a neurorestorative therapy in stroke

Prevalence of pulmonary embolism in patients with suspected cardioembolic ischemic stroke

Effects of intensive therapy using gait trainer or floor walking exercise early after stroke

Restoration of normal cortical excitability and gait ability in acute stroke after intensive rehabilitation

Effects of intensive gait-oriented physiotherapy during early acute phase of stroke