Timo Lakka
Professor
Professor of Medical Physiology
Institute of Biomedicine, School of Medicine, Faculty of Health Sciences
[email protected] | +358 40 770 7329
Timo Lakka is a Professor of Medical Physiology at University of Eastern Finland, a Specialist in Internal Medicine, and an Adjunct Professor of Public Health. His research is focused on the identification of individuals at increased risk of overweight, metabolic syndrome, type 2 diabetes, and atherosclerotic cardiovascular diseases and the prevention of these diseases and conditions by increasing physical activity and improving diet since childhood. He is a Principal Investigator in the Physical Activity and Nutrition in Children (PANIC) study and a Co-Principal Investigator in the Stop Diabetes (StopDia) study and the Dose Responses to Exercise Training (DR’s EXTRA) study. He has also acted as a senior researcher in many other large-scale lifestyle intervention studies, long-term epidemiological follow-up studies, and wide international genetic-epidemiological studies. He has published over 360 scientific articles in international journals, and these articles have almost 60 000 citations and a h-index of 106 (Google Scholar). He has supervised 24 doctoral theses and is a supervisor of another 13 doctoral students.
Research groups
Publications
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Accelerated early childhood growth associates with the development of earlier adrenarche and puberty
Liimatta, Jani; Jääskeläinen, Jarmo; Mäntyselkä, Aino; Häkkinen, Merja R; Auriola, Seppo; Voutilainen, Raimo; Flück, Christa E; Lakka, Timo A. 2024. Journal of the Endocrine Society. 8: . bvae026 A1 Journal article (refereed), original research -
Accumulating Sedentary Time and Physical Activity From Childhood to Adolescence and Cardiac Function in Adolescence
Haapala, Eero A; Leppänen, Marja H; Lee, Earric; Savonen, Kai; Laukkanen, Jari A; Kähönen, Mika; Brage, Soren; Lakka, Timo A. 2024. Journal of the american heart association: Cardiovascular and cerebrovascular disease. 13: A1 Journal article (refereed), original research -
Association between arterial health and cognition in adolescents: The PANIC study
Jalanko, Petri; Bond, Bert; Laukkanen, Jari A; Brage, Soren; Ekelund, Ulf; Laitinen, Tomi; Määttä, Sara; Kähönen, Mika; Haapala, Eero A; Lakka, Timo A. 2024. Physiological reports. 12: . e16024 A1 Journal article (refereed), original research -
Associations of Cardiovascular Health Metrics in Childhood and Adolescence With Arterial Health Indicators in Adolescence: The PANIC Study
Kraav, Juta; Zagura, Maksim; Viitasalo, Anna; Soininen, Sonja; Veijalainen, Aapo; Kähönen, Mika; Jürimäe, Jaak; Tillmann, Vallo; Haapala, Eero; Lakka, Timo. 2024. Journal of the american heart association: Cardiovascular and cerebrovascular disease. 13: A1 Journal article (refereed), original research -
Associations of Lifestyle Patterns with Glucose and Lipid Metabolism in Finnish Adults at Increased Risk of Type 2 Diabetes
Manninen, Suvi; Tilles‐Tirkkonen, Tanja; Aittola, Kirsikka; Männikkö, Reija; Karhunen, Leila; Kolehmainen, Marjukka; Schwab, Ursula; Lindström, Jaana; Lakka, Timo; Pihlajamäki, Jussi; the Stop Diabetes study group. 2024. Molecular nutrition and food research. 68: A1 Journal article (refereed), original research -
Associations of physical fitness with cortical inhibition and excitation in adolescents and young adults
Skog, Hanna Mari; Määttä, Sara; Säisanen, Laura; Lakka, Timo A; Haapala, Eero A. 2024. Frontiers in neuroscience. 18: A1 Journal article (refereed), original research -
Childhood Physical Fitness as a Predictor of Cognition and Mental Health in Adolescence: The PANIC Study
Haapala, Eero A; Leppänen, Marja H; Skog, Hannamari; Lubans, David R; Viitasalo, Anna; Lintu, Niina; Jalanko, Petri; Määttä, Sara; Lakka, Timo A. 2024. Sports medicine. [Published: 10 September 2024]: 1-11 A1 Journal article (refereed), original research -
Cross-sectional and longitudinal associations between the 24-hour movement behaviours, including muscle and bone strengthening activity, with bone and lean mass from childhood to adolescence
Skinner, Annie M; Barker, Alan R; Moore, Sarah A; Soininen, Sonja; Haapala, Eero A; Väistö, Juuso; Westgate, Kate; Brage, Soren; Lakka, Timo A; Vlachopoulos, Dimitris. 2024. Bmc public health. 24: . 227 A1 Journal article (refereed), original research -
Eight-year Diet and Physical Activity Intervention Affects Serum Metabolites during Childhood & Adolescence: A Nonrandomized Controlled Trial
Zarei, Iman; Eloranta, Aino-Maija; Klåvus, Anton; Väistö, Juuso; Lehtonen, Marko; Mikkonen, Santtu; Koistinen, Ville M; Sallinen, Taisa; Haapala, Eero A; Lintu, Niina; Soininen, Sonja; Haikonen, Retu; Atalay, Mustafa; Schwab, Ursula; Auriola, Seppo; Kolehmainen, Marjukka; Hanhineva, Kati; Lakka, Timo A. 2024. iScience. 27: A1 Journal article (refereed), original research -
Increased adiposity in juvenile idiopathic arthritis – A comparison of the bioelectrical impedance analysis and dual‐energy X‐ray absorptiometry for the assessment of body composition
Räsänen, Kati; Soisalo, Katja; Markula‐Patjas, Kati; Kantanen, Saija; Sipilä, Kalle; Lakka, Timo A; Valve‐Dietz, Anna‐Kaisa; Piippo‐Savolainen, Eija; Arikoski, Pekka. 2024. Acta paediatrica. 113: 2072-2080 A1 Journal article (refereed), original research -
Longitudinal associations of an exposome score with serum metabolites from childhood to adolescence
Healy, Darren R; Zarei, Iman; Mikkonen, Santtu; Soininen, Sonja; Viitasalo, Anna; Haapala, Eero A; Auriola, Seppo; Hanhineva, Kati; Kolehmainen, Marjukka; Lakka, Timo A. 2024. Communications biology. 7: . 890 A1 Journal article (refereed), original research -
Luonnossa vietetyn ajan ja liikunnan yhteydet positiiviseen mielenterveyteen työelämän ulkopuolella olevilla pohjoissavolaisilla
Rekola, Hanna; Kurkinen, Karoliina; Tolmunen, Tommi; Pentikäinen, Heikki; Lakka, Timo A; Mäki-Opas, Tomi. 2024. Liikunta ja tiede. 61: 105-111 A1 Journal article (refereed), original research -
Maternal gestational hypertension, smoking and pre‐eclampsia are associated with metabolic dysfunction‐associated fatty liver disease in overweight offspring
de Ruyter, Hanna; Aitokari, Linnea; Lahti, Siiri; Riekki, Hanna; Huhtala, Heini; Lakka, Timo; Laivuori, Hannele; Kurppa, Kalle. 2024. Acta obstetricia et gynecologica scandinavica. 103: 1183-1191 A1 Journal article (refereed), original research -
Multiple androgen pathways contribute to the steroid signature of adrenarche
Liimatta, Jani; du Toit, Therina; Voegel, Clarissa D; Jääskeläinen, Jarmo; Lakka, Timo A; Flück, Christa E. 2024. Molecular and cellular endocrinology. 592: A1 Journal article (refereed), original research -
Prenatal Urban Environment and Blood Pressure Trajectories From Childhood to Early Adulthood
Gonçalves Soares, Ana; Santos, Susana; Seyve, Emie; Nedelec, Rozenn; Puhakka, Soile; Eloranta, Aino-Maija; Mikkonen, Santtu; Yuan, Wen Lun; Lawlor, Deborah A.; Heron, Jon; Vrijheid, Martine; Lepeule, Johanna; Nieuwenhuijsen, Mark; Fossati, Serena; Jaddoe, Vincent W.V.; Lakka, Timo; Sebert, Sylvain; Heude, Barbara; Felix, Janine F.; Elhakeem, Ahmed; Timpson, Nicholas J.. 2024. JACC : advances. 3: A1 Journal article (refereed), original research -
Psychological well-being of children and adolescents with inflammatory bowel disease
Vekara, Laura; Kantanen, Saija; Kolho, Kaija Leena; Räsänen, Kati; Lakka, Timo; Huhtala, Heini; Piippo-Savolainen, Eija; Arikoski, Pekka; Hiltunen, Pauliina. 2024. Journal of pediatric gastroenterology and nutrition. 78: 1287-1296 A1 Journal article (refereed), original research -
The associations of depressive symptoms and perceived stress with arterial health in adolescents
Toivonen, Emmi; Lee, Earric; Leppänen, Marja H; Laitinen, Tomi; Kähoenen, Mika; Lakka, Timo A; Haapala, Eero A. 2024. Physiological reports. 12: A1 Journal article (refereed), original research -
Alanine aminotransferase cutoffs for the pediatric fatty liver disease: Major impact of the reference population
Aitokari, Linnea; Lahti, Siiri; Kivelä, Laura; Riekki, Hanna; Hiltunen, Pauliina; Vuorela, Nina; Viitasalo, Anna; Soininen, Sonja; Huhtala, Heini; Lakka, Timo; Kurppa, Kalle. 2023. Journal of pediatric gastroenterology and nutrition. 2024; 78: 488-496 A1 Journal article (refereed), original research -
Associations Between Engagement with the BitHabit Digital Lifestyle Intervention and Changes in Type 2 Diabetes Risk Factors
Liedes, Hilkka; Mattila, Elina; Honka, Anita; Absetz, Pilvikki; Aittola, Kirsikka; Manninen, Suvi; Lintu, Niina; Schwab, Ursula; Eloranta, Aino-Maija; Umer, Adil; Tilles-Tirkkonen, Tanja; Männikkö, Reija; Ruotsalainen, Ilona; Van Gils, Mark; Lindström, Jaana; Lakka, Timo; Pihlajamäki, Jussi; Vuorinen, Anna-Leena. 2023. Studies in health technology and informatics abstract -
Associations between physical fitness and cerebellar gray matter volume in adolescents
Jalanko, Petri; Säisänen, Laura; Kallioniemi, Elisa; Könönen, Mervi; Lakka, Timo A; Määttä, Sara; Haapala, Eero A. 2023. Scandinavian journal of medicine and science in sports. 2024; 34: A1 Journal article (refereed), original research -
Associations of diet quality and food consumption with serum biomarkers for lipid and amino acid metabolism in Finnish children: the PANIC study
Laamanen, Suvi E; Eloranta, Aino Maija; Haapala, Eero A; Sallinen, Taisa; Schwab, Ursula; Lakka, Timo A. 2023. European journal of nutrition. 2024; 63: 623-637 A1 Journal article (refereed), original research -
Bone mineral density loci specific to the skull portray potential pleiotropic effects on craniosynostosis
Medina-Gomez, Carolina; Mullin, Benjamin H.; Chesi, Alessandra; Prijatelj, Vid; Kemp, John P.; Shochat-Carvalho, Chen; Trajanoska, Katerina; Wang, Carol; Joro, Raimo; Evans, Tavia E.; Schraut, Katharina E.; Li-Gao, Ruifang; Ahluwalia, Tarunveer S.; Zillikens, M. Carola; Zhu, Kun; Mook-Kanamori, Dennis O.; Evans, Daniel S.; Nethander, Maria; Knol, Maria J.; Thorleifsson, Gudmar; Prokic, Ivana; Zemel, Babette; Broer, Linda; McGuigan, Fiona E.; van Schoor, Natasja M.; Reppe, Sjur; Pawlak, Mikolaj A. 2023. Communications biology. 6: A1 Journal article (refereed), original research -
Cross-Lagged Associations between Physical Activity, Motor Performance, and Academic Skills in Primary-School Children
Haapala, Eero A; Widlund, Anna; Poikkeus, Anna-Maija; Lima, Rodrigo Antunes; Brage, Soren; Aunio, Pirjo; Lakka, Timo A. 2023. Medicine and science in sports and exercise. 55: 1465-1470 A1 Journal article (refereed), original research -
Cross-sectional associations between physical fitness and biomarkers of inflammation in children—The PANIC study
Haapala, Eero A; Kuronen, Emmi; Ihalainen, Johanna K; Lintu, Niina; Leppänen, Marja H; Tompuri, Tuomo; Atalay, Mustafa; Schwab, Ursula; Lakka, Timo A. 2023. Scandinavian journal of medicine and science in sports. 33: 1000-1009 A1 Journal article (refereed), original research -
Developmental models of motor-evoked potential features by transcranial magnetic stimulation across age groups from childhood to adulthood
Nguyen, Dao T A; Julkunen, Petro; Säisänen, Laura; Määttä, Sara; Rissanen, Saara M; Lintu, Niina; Könönen, Mervi; Lakka, Timo; Karjalainen, Pasi A. 2023. Scientific reports. 13: A1 Journal article (refereed), original research -
Digitaalisella hyvinvointisovelluksella voidaan mitata mielen hyvinvointia ja elintapoja sekä toteuttaa näiden edistämistä tukevia interventioita
Rekola, Hanna; Sveins, Petteri; Tenhunen, Juha; Strömmer, Juho; Borgström, Joni; Paronen, Elsa; Surakka, Anne; Saijonkari, Maija; Pentikäinen, Heikki; Lakka, Timo; Mäki-Opas, Tomi. 2023. . . Itä-Suomen yliopisto D4 Published development or research report or study -
Effects of 2-Year Physical Activity and Dietary Intervention on Adrenarchal and Pubertal Development: The PANIC Study
Liimatta, Jani; Flück, Christa E; Mäntyselkä, Aino; Häkkinen, Merja R; Auriola, Seppo; Voutilainen, Raimo; Jääskelainen, Jarmo; Lakka, Timo A. 2023. Journal of clinical endocrinology and metabolism. 108: e1603-e1613 A1 Journal article (refereed), original research -
Effects of 2‐year dietary and physical activity intervention on cognition in children—a nonrandomized controlled trial
Naveed, Sehrish; Sallinen, Taisa; Eloranta, Aino‐Maija; Skog, Hannamari; Jalkanen, Henna; Brage, Soren; Ekelund, Ulf; Pentikäinen, Heikki; Savonen, Kai; Lakka, Timo A.; Haapala, Eero A.. 2023. Scandinavian journal of medicine and science in sports. 33: 2340-2350 A1 Journal article (refereed), original research -
European fitness landscape for children and adolescents: updated reference values, fitness maps and country rankings based on nearly 8 million test results from 34 countries gathered by the FitBack network
Ortega, Francisco B; Leskošek, Bojan; Blagus, Rok; Gil-Cosano, José J; Mäestu, Jarek; Tomkinson, Grant R; Ruiz, Jonatan R; Mäestu, Evelin; Starc, Gregor; Milanovic, Ivana; Tammelin, Tuija H; Sorić, Maroje; Scheuer, Claude; Carraro, Attilio; Kaj, Mónika; Csányi, Tamás; Sardinha, Luis B; Lenoir, Matthieu; Emeljanovas, Arunas; Mieziene, Brigita; Sidossis, Labros S; Pihu, Maret; Lovecchio, Nicola; Konstabel, Kenn; Tambalis, Konstantinos D; Štefan, Lovro; Drenowatz, Clemens; Rubín, Lukáš; Gontarev, S. 2023. British journal of sports medicine. 57: 299-310 A1 Journal article (refereed), original research -
Evidence for protein leverage in a general population sample of children and adolescents
Saner, Christoph; Senior, Alistair M; Zhang, Hanyue; Eloranta, Aino-Maija; Magnussen, Costan G; Sabin, Matthew A; Juonala, Markus; Janner, Marco; Burgner, David P; Schwab, Ursula; Haapala, Eero A; Heitmann, Berit L; Simpson, Stephen J; Raubenheimer, David; Lakka, Timo A. 2023. European journal of clinical nutrition. 77: 652-659 A1 Journal article (refereed), original research -
Gene-educational attainment interactions in a multi-population genome-wide meta-analysis identify novel lipid loci
de las Fuentes, Lisa; Schwander, Karen L; Brown, Michael R; Bentley, Amy R; Winkler, Thomas W; Sung, Yun Ju; Munroe, Patricia B; Miller, Clint L; Aschard, Hugo; Aslibekyan, Stella; Bartz, Traci M; Bielak, Lawrence F; Chai, Jin Fang; Cheng, Ching-Yu; Dorajoo, Rajkumar; Feitosa, Mary F; Guo, Xiuqing; Hartwig, Fernando P; Horimoto, Andrea; Kolčić, Ivana; Lim, Elise; Liu, Yongmei; Manning, Alisa K; Marten, Jonathan; Musani, Solomon K; Noordam, Raymond; Padmanabhan, Sandosh; Rankinen, Tuomo; Richard,. 2023. Frontiers in genetics. 14: . 1235337 A1 Journal article (refereed), original research -
Genome-wide association study and functional characterization identifies candidate genes for insulin-stimulated glucose uptake
Williamson, Alice; Norris, Dougall M.; Yin, Xianyong; Broadaway, K. Alaine; Moxley, Anne H.; Vadlamudi, Swarooparani; Wilson, Emma P.; Jackson, Anne U.; Ahuja, Vasudha; Andersen, Mette K.; Arzumanyan, Zorayr; Bonnycastle, Lori L.; Bornstein, Stefan R.; Bretschneider, Maxi P.; Buchanan, Thomas A.; Chang, Yi-Cheng; Chuang, Lee-Ming; Chung, Ren-Hua; Clausen, Tine D.; Damm, Peter; Delgado, Graciela E.; de Mello, Vanessa D.; Dupuis, Josée; Dwivedi, Om P.; Erdos, Michael R.; Silva, Lilian Fernandes; F. 2023. Nature genetics. 55: 973-983 A1 Journal article (refereed), original research -
Genome-wide association study of placental weight identifies distinct and shared genetic influences between placental and fetal growth
Beaumont, Robin N.; Flatley, Christopher; Vaudel, Marc; Wu, Xiaoping; Chen, Jing; Moen, Gunn-Helen; Skotte, Line; Helgeland, Øyvind; Solé-Navais, Pol; Banasik, Karina; Albiñana, Clara; Ronkainen, Justiina; Fadista, João; Stinson, Sara Elizabeth; Trajanoska, Katerina; Wang, Carol A.; Westergaard, David; Srinivasan, Sundararajan; Sánchez-Soriano, Carlos; Bilbao, Jose Ramon; Allard, Catherine; Groleau, Marika; Kuulasmaa, Teemu; Leirer, Daniel J.; White, Frédérique; Jacques, Pierre-Étienne; Cheng, H. 2023. Nature genetics. 55: 1807-1819 A1 Journal article (refereed), original research -
Impaired cardiorespiratory and neuromuscular fitness in children and adolescents with juvenile idiopathic arthritis: a cross-sectional case-control study in the era of biologic drug therapies
Räsänen, Kati; Markula-Patjas, Kati; Kantanen, Saija; Sipilä, Kalle; Lakka, Timo A.; Arikoski, Pekka; Piippo-Savolainen, Eija. 2023. Pediatric rheumatology. 21: A1 Journal article (refereed), original research -
Large-scale exome array summary statistics resources for glycemic traits to aid effector gene prioritization
Willems, Sara M; Ng, Natasha H J; Fernandez, Juan; Fine, Rebecca S; Wheeler, Eleanor; Wessel, Jennifer; Kitajima, Hidetoshi; Marenne, Gaelle; Sim, Xueling; Yaghootkar, Hanieh; Wang, Shuai; Chen, Sai; Chen, Yuning; Chen, Yii-Der Ida; Grarup, Niels; Li-Gao, Ruifang; Varga, Tibor V; Asimit, Jennifer L; Feng, Shuang; Strawbridge, Rona J; Kleinbrink, Erica L; Ahluwalia, Tarunveer S; An, Ping; Appel, Emil V; Arking, Dan E; Auvinen, Juha; Bielak, Lawrence F; Bihlmeyer, Nathan A; Bork-Jensen, Jette; Bro. 2023. Wellcome open research. 8: A1 Journal article (refereed), original research -
Parempaa mielenterveyden edistämistä Pohjois-Savossa kuntien mielenterveysjohtamisen käsitettä ja tavoitteita täsmentämällä sekä tiedolla johtamista kehittämällä
Rekola, Hanna; Surakka, Anne; Saijonkari, Maija; Mäki-Opas, Tomi; Lakka, Timo; Paronen, Elsa. 2023. . . Itä-Suomen yliopisto D4 Published development or research report or study -
Prevalence and associated factors of metabolic-associated fatty liver disease in overweight Finnish children and adolescents
Riekki, Hanna; Aitokari, Linnea; Kivela, Laura; Lahti, Siiri; Hiltunen, Pauliina; Vuorela, Nina; Huhtala, Heini; Lakka, Timo A.; Kurppa, Kalle. 2023. Frontiers in endocrinology. 14: A1 Journal article (refereed), original research -
Promotive and preventive interventions for mental health and well-being in adult populations: a systematic umbrella review
Saijonkari, Maija; Paronen, Elsa; Lakka, Timo; Tolmunen, Tommi; Linnosmaa, Ismo; Lammintakanen, Johanna; Isotalo, Jenni; Rekola, Hanna; Mäki-Opas, Tomi. 2023. Frontiers in public health. 11: . 1201552 A2 Review article, Literature review, Systematic review -
A participatory arts programme – Shared experience for family caregivers and care recipients
Vaajoki, Anne; Turjamaa, Riitta; Lakka, Timo; Mäkinen, Eeva; Välimäki, Tarja. 2022. Nursing open. 2023; 10: 3011-3017 A1 Journal article (refereed), original research -
A quantitative ultra-performance liquid chromatography high-resolution mass spectrometry analysis of steroids from human scalp hair
Koskivuori, Johanna; Voutilainen, Raimo; Uusitalo, Lauri; Lehtonen, Marko; Lakka, Timo; Auriola, Seppo; Häkkinen, Merja R. 2022. Journal of pharmaceutical and biomedical analysis. 215: A1 Journal article (refereed), original research -
ACE2 expression in adipose tissue is associated with cardio-metabolic risk factors and cell type composition—implications for COVID-19
El-Sayed Moustafa, Julia S.; Jackson, Anne U.; Brotman, Sarah M.; Guan, Li; Villicaña, Sergio; Roberts, Amy L.; Zito, Antonino; Bonnycastle, Lori; Erdos, Michael R.; Narisu, Narisu; Stringham, Heather M.; Welch, Ryan; Yan, Tingfen; Lakka, Timo; Parker, Stephen; Tuomilehto, Jaakko; Seow, Jeffrey; Graham, Carl; Huettner, Isabella; Acors, Sam; Kouphou, Neophytos; Wadge, Samuel; Duncan, Emma L.; Steves, Claire J.; Doores, Katie J.; Malim, Michael H.; Collins, Francis S.; Pajukanta, Päivi; Boehnke, M. 2022. International journal of obesity. 46: 1478-1486 A1 Journal article (refereed), original research -
Associations between weight loss history and factors related to type 2 diabetes risk in the Stop Diabetes study
Halali, F; Lapveteläinen, A; Aittola, K; Männikkö, R; Tilles-Tirkkonen, T; Järvelä-Reijonen, E; Absetz, P; Kolehmainen, M; Schwab, U; Lindström, J; Lakka, TA; Pihlajamäki, J; Karhunen, L. 2022. International journal of obesity. 46: 935-942 A1 Journal article (refereed), original research -
Associations of diet quality, food consumption, eating frequency, and eating behaviour with dental caries experience in Finnish children: A 2-year longitudinal study
Virkkala, Veera; Eloranta, Aino-Maija; Suominen, Anna Liisa; Vierola, Anu; Ikävalko, Tiina; Väistö, Juuso; Mikkonen, Santtu; Methuen, Mirja; Schwab, Ursula; Viljakainen, Heli; Leinonen, Jukka; Närhi, Matti; Lakka, Timo A.. 2022. British journal of nutrition. [Published 08 August 2022]: 1-11 A1 Journal article (refereed), original research -
Cross-sectional associations between cardiorespiratory fitness and NMR-derived metabolic biomarkers in children – the PANIC study
Haapala, Eero A.; Leppänen, Marja H.; Lehti, Maarit; Lintu, Niina; Tompuri, Tuomo; Viitasalo, Anna; Schwab, Ursula; Lakka, Timo A.. 2022. Frontiers in endocrinology. 13: . 954418 A1 Journal article (refereed), original research -
Determinants of Cognitive Performance in Children and Adolescents : A Populational Longitudinal Study
Lima, Rodrigo Antunes; Soares, Fernanda Cunha; van Poppel, Mireille; Savinainen, Saija; Mäntyselkä, Aino; Haapala, Eero A; Lakka, Timo. 2022. International journal of environmental research and public health. 19: . 8955 A1 Journal article (refereed), original research -
Digitally Supported Lifestyle Intervention to Prevent Type 2 Diabetes Through Healthy Habits: Secondary Analysis of Long-Term User Engagement Trajectories in a Randomized Controlled Trial
Lavikainen, Piia; Mattila, Elina; Absetz, Pilvikki; Harjumaa, Marja; Lindström, Jaana; Järvelä-Reijonen, Elina; Aittola, Kirsikka; Männikkö, Reija; Tilles-Tirkkonen, Tanja; Lintu, Niina; Lakka, Timo; van Gils, Mark; Pihlajamäki, Jussi; Martikainen, Janne. 2022. Journal of medical internet research. 24: A1 Journal article (refereed), original research -
Is low cardiorespiratory fitness a feature of metabolic syndrome in children and adults?
Haapala, Eero A.; Tompuri, Tuomo; Lintu, Niina; Viitasalo, Anna; Savonen, Kai; Lakka, Timo A.; Laukkanen, Jari A.. 2022. Journal of science and medicine in sport. 25: 923-929 A1 Journal article (refereed), original research -
Lapsuuden suun terveydenhuollon käynnit ja vanhempien sosioekonominen asema
Tolonen, Ville; Ikävalko, Tiina; Suominen, Liisa; Lakka, Timo; Karvinen, Henri; Törmälehto, Soili; Raittio, Eero. 2022. Suomen hammaslääkärilehti. 29: 44-50 A1 Journal article (refereed), original research -
LongITools: Dynamic longitudinal exposome trajectories in cardiovascular and metabolic noncommunicable diseases
Ronkainen, Justiina; Nedelec, Rozenn; Atehortua, Angelica; Balkhiyarova, Zhanna; Cascarano, Anna; Ngoc Dang, Vien; Elhakeem, Ahmed; van Enckevort, Esther; Goncalves Soares, Ana; Haakma, Sido; Halonen, Miia; Heil, Katharina F.; Heiskala, Anni; Hyde, Eleanor; Jacquemin, Bénédicte; Keikkala, Elina; Kerckhoffs, Jules; Klåvus, Anton; Kopinska, Joanna A.; Lepeule, Johanna; Marazzi, Francesca; Motoc, Irina; Näätänen, Mari; Ribbenstedt, Anton; Rundblad, Amanda; Savolainen, Otto; Simonetti, Valentina; de. 2022. Environmental epidemiology. 6: A1 Journal article (refereed), original research -
Mielenterveys- ja päihdeongelmat työelämän ulkopuolella olevilla pohjoissavolaisilla
Kurkinen, Karoliina; Karjalainen, Panu; Rekola, Hanna; Pietikäinen, Liisa; Laakso, Seija; Laine, Katja; Surakka, Anne; Saijonkari, Maija; Lakka, Timo; Mäki-Opas, Tomi; Tolmunen, Tommi. 2022. University of Eastern Finland other -
Physical activity volume and intensity distribution in relation to bone, lean and fat mass in children
Skinner, Annie M.; Vlachopoulos, Dimitris; Barker, Alan R.; Moore, Sarah A.; Rowlands, Alex V.; Soininen, Sonja; Haapala, Eero A.; Väistö, Juuso; Westgate, Kate; Brage, Soren; Lakka, Timo A.. 2022. Scandinavian journal of medicine and science in sports. 2023; 33: 267-282 A1 Journal article (refereed), original research -
Prevalence of erosive tooth wear and associated dietary factors among a group of Finnish adolescents
Methuen, Mirja; Kangasmaa, Hanna; Alaraudanjoki, Viivi Karoliina; Suominen, Anna L.; Anttonen, Vuokko; Vähänikkilä, Hannu; Karjalainen, Panu; Väistö, Juuso; Lakka, Timo A.; Laitala, Marja-Liisa. 2022. Caries research. 56: 477-487 A1 Journal article (refereed), original research -
Real-world effectiveness of digital and group-based lifestyle interventions as compared with usual care to reduce type 2 diabetes risk – A stop diabetes pragmatic randomised trial
Lakka, Timo A.; Aittola, Kirsikka; Järvelä-Reijonen, Elina; Tilles-Tirkkonen, Tanja; Männikkö, Reija; Lintu, Niina; Karhunen, Leila; Kolehmainen, Marjukka; Harjumaa, Marja; Mattila, Elina; Järvenpää, Riia; Ermes, Miikka; Mikkonen, Santtu; Martikainen, Janne; Poutanen, Kaisa; Schwab, Ursula; Absetz, Pilvikki; Lindström, Jaana; Pihlajamäki, Jussi. 2022. The Lancet regional health : Europe. 2023; 24: A1 Journal article (refereed), original research -
Sources of vitamin D and determinants of serum 25-hydroxyvitamin D in Finnish adolescents
Soininen, Sonja; Eloranta, Aino-Maija; Schwab, Ursula; Lakka, Timo A. 2022. European journal of nutrition. 2023; 62: 1011-1025 A1 Journal article (refereed), original research -
The Composition and Functional Capacities of Saliva Microbiota Differ Between Children With Low and High Sweet Treat Consumption
Lommi, Sohvi; Manzoor, Muhammed; Engberg, Elina; Agrawal, Nitin; Lakka, Timo A.; Leinonen, Jukka; Kolho, Kaija-Leena; Viljakainen, Heli. 2022. Frontiers in nutrition. 9: . 864687 A1 Journal article (refereed), original research -
The Mediating Role of Endocrine Factors in the Positive Relationship Between Fat Mass and Bone Mineral Content in Children Aged 9–11 Years: The Physical Activity and Nutrition in Children Study
Constable, Annie M.; Vlachopoulos, Dimitris; Barker, Alan R.; Moore, Sarah A.; Soininen, Sonja; Haapala, Eero A.; Väistö, Juuso; Jääskeläinen, Jarmo; Voutilainen, Raimo; Auriola, Seppo; Häkkinen, Merja R.; Laitinen, Tomi; Lakka, Timo A.. 2022. Frontiers in endocrinology. 13: . 850448 A1 Journal article (refereed), original research -
The effects of an 8-year individualised lifestyle intervention on food consumption and nutrient intake from childhood to adolescence: the PANIC Study
Sallinen, Taisa; Viitasalo, Anna; Lintu, Niina; Väistö, Juuso; Soininen, Sonja; Jalkanen, Henna; Haapala, Eero A.; Mikkonen, Santtu; Schwab, Ursula; Lakka, Timo A.; Eloranta, Aino-Maija. 2022. Journal of nutritional science. 11: A1 Journal article (refereed), original research -
Työelämän ulkopuolella olevien positiivista mielenterveyttä tulee parantaa edistämällä terveellisiä elintapoja ja tarjoamalla matalan kynnyksen palveluita
Rekola, Hanna; Kurkinen, Karoliina; Tolmunen, Tommi; Saijonkari, Maija; Surakka, Anne; Pentikäinen, Heikki; Lakka, Timo A; Paronen, Elsa; Mäki-Opas, Tomi. 2022. University of Eastern Finland other -
Associations of physical activity, sedentary time, and diet quality with biomarkers of inflammation in children
Haapala, Eero A; Väistö, Juuso; Ihalainen, Johanna K; Tomaselli González, Claudia; Leppänen, Marja H; Veijalainen, Aapo; Sallinen, Taisa; Eloranta, Aino-Maija; Ekelund, Ulf; Schwab, Ursula; Brage, Soren; Atalay, Mustafa; Lakka, Timo A. 2021. European journal of sport science. [Epub ahead of print 14 March 2021]: 1-10 A1 Journal article (refereed), original research -
Comparison of Communication Channels for Large-Scale Type 2 Diabetes Risk Screening and Intervention Recruitment: Empirical Study
Jalkanen, Kari; Järvenpää, Riia; Tilles-Tirkkonen, Tanja; Martikainen, Janne; Aarnio, Emma; Männikkö, Reija; Rantala, Eeva; Karhunen, Leila; Kolehmainen, Marjukka; Harjumaa, Marja; Poutanen, Kaisa; Ermes, Miikka; Absetz, Pilvikki; Schwab, Ursula; Lakka, Timo; Pihlajamäki, Jussi; Lindström, Jaana; The StopDia Study Group. 2021. JMIR diabetes. 6: e21356 A1 Journal article (refereed), original research -
Cost-effectiveness of physical activity intervention in children - results based on the Physical Activity and Nutrition in Children (PANIC) study
Kuvaja-Köllner, Virpi; Lintu, Niina; Lindi, Virpi; Rissanen, Elisa; Eloranta, Aino-Maija; Kiiskinen, Sanna; Martikainen, Janne; Kankaanpää, Eila; Valtonen, Hannu; Lakka, Timo A.. 2021. International journal of behavioral nutrition and physical activity. 18: 116 A1 Journal article (refereed), original research -
Dental caries among Finnish teenagers participating in physical activity and diet intervention: association with anthropometrics and behavioural factors
Methuen, Mirja; Kauppinen, Sofia; Suominen, Anna Liisa; Eloranta, Aino-Maija; Väistö, Juuso; Lakka, Timo; Vähänikkilä, Hannu; Anttonen, Vuokko. 2021. Bmc oral health. 21: 333 A1 Journal article (refereed), original research -
Enhanced Eating Competence Is Associated with Improved Diet Quality and Cardiometabolic Profile in Finnish Adults with Increased Risk of Type 2 Diabetes
Aittola, Kirsikka; Karhunen, Leila; Männikkö, Reija; Järvelä-Reijonen, Elina; Mikkonen, Santtu; Absetz, Pilvikki; Kolehmainen, Marjukka; Schwab, Ursula; Harjumaa, Marja; Lindström, Jaana; Lakka, Timo; Tilles-Tirkkonen, Tanja; Pihlajamäki, Jussi. 2021. Nutrients. 13: 4030 A1 Journal article (refereed), original research -
Exercise, diet, and cognition in a 4-year randomized controlled trial: Dose-Responses to Exercise Training (DR's EXTRA)
Komulainen, Pirjo; Tuomilehto, Jaakko; Savonen, Kai; Männikkö, Reija; Hassinen, Maija; Lakka, Timo A; Hänninen, Tuomo; Kiviniemi, Vesa; Jacobs, David R; Kivipelto, Miia; Rauramaa, Rainer. 2021. American journal of clinical nutrition. 113: 1428-1439 A1 Journal article (refereed), original research -
Hyvällä mielellä Pohjois-Savo -hankkeen esiselvitys: Toimenpide-ehdotus ja vaikuttavuuden arviointisuunnitelma
Saijonkari, Maija; Paronen, Elsa; Lakka, Timo; Tolmunen, Tommi; Linnosmaa, Ismo; Lammintakanen, Johanna; Mäki-Opas, Tomi. 2021. Publications of the University of Eastern Finland. General series. . D4 Published development or research report or study -
Liikunnallisuus ja hyvä kunto ehkäisevät tyypin 2 diabetesta ja valtimotautien riskitekijöitä lapsuudesta lähtien
Väistö, Juuso; Haapala, Eero; Lakka, Timo A. 2021. Liikunta ja tiede. 58: 62-64 D1 Article in a trade journal -
Longitudinal and cross-sectional associations of adherence to 24-hour movement guidelines with cardiometabolic risk
Leppänen, Marja H; Haapala, Eero A; Väistö, Juuso; Ekelund, Ulf; Brage, Søren; Kilpeläinen, Tuomas O; Lakka, Timo A. 2021. Scandinavian journal of medicine and science in sports. 2022; 32: 255-266 A1 Journal article (refereed), original research -
Longitudinal associations of physical activity, sedentary time, and cardiorespiratory fitness with arterial health in children - the PANIC study
Korhonen, Marika; Väisto, Juuso; Veijalainen, Aapo; Leppänen, Marja; Ekelund, Ulf; Laukkanen, Jari A; Brage, Soren; Lintu, Niina; Haapala, Eero A; Lakka, Timo A. 2021. Journal of sports sciences. 39: 1980-1987 A1 Journal article (refereed), original research -
Multi-ancestry genome-wide association study accounting for gene-psychosocial factor interactions identifies novel loci for blood pressure traits
Sun, Daokun; Richard, Melissa A.; Musani, Solomon K.; Sung, Yun Ju; Winkler, Thomas W.; Schwander, Karen; Chai, Jin Fang; Guo, Xiuqing; Kilpeläinen, Tuomas O.; Vojinovic, Dina; Aschard, Hugues; Bartz, Traci M.; Bielak, Lawrence F.; Brown, Michael R.; Chitrala, Kumaraswamy; Hartwig, Fernando P.; Horimoto, Andrea R.V.R.; Liu, Yongmei; Manning, Alisa K.; Noordam, Raymond et al. [incl. Heikkinen, Sami; Lakka, Timo]. 2021. HGG advances. 2: 100013 A1 Journal article (refereed), original research -
Oxygen-18 and Carbon-13 isotopes in eCO 2 and erythrocytes carbonic anhydrase activity of Finnish prediabetic population
Kårlund, Anna; Kääriäinen, Teemu; Kostamo, Vili M; Kokkola, Tarja; Kolehmainen, Marjukka; Lakka, Timo A; Pihlajamäki, Jussi; Manninen, Albert. 2021. Journal of breath research. 15: 21001 A1 Journal article (refereed), original research -
Plasma irisin and its associations with oxidative stress in athletes suffering from overtraining syndrome
Joro, R; Korkmaz, A; Lakka, TA; Uusitalo, ALT; Atalay, M. 2021. Physiology international. 10: 513-526 A1 Journal article (refereed), original research -
Response
Haapala, Eero A; Barker, Alan R; Lakka, Timo A. 2021. Medicine and science in sports and exercise. 53: 454 B1 Non-refereed journal articles -
Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability
Mägi, Reedik; Hottenga, Jouke- Jan; Grallert, Harald; Perry, John R. B.; Bouatia-Naji, Nabila; Marullo, Letizia; Rybin, Denis; Jansen, Rick; Min, Josine L.; Dimas, Antigone S.; Ulrich, Anna; Zudina, Liudmila; Gådin, Jesper R.; Jiang, Longda; Faggian, Alessia; Bonnefond, Amélie; Fadista, Joao; Stathopoulou, Maria G.; Isaacs, Aaron; Willems, Sara M et al. [incl. Kuusisto, Johanna; Laakso, Markku; Lakka, Timo, Uusitupa, Matti]. 2021. Nature communications. 12: 24 A1 Journal article (refereed), original research -
The Positive Relationship between Moderate-to-Vigorous Physical Activity and Bone Mineral Content Is Not Mediated by Free Leptin Index in Prepubertal Children: The PANIC Study
Constable, Annie M.; Porter, Josie E.; Benger, Danielle; Vlachopoulos, Dimitris; Barker, Alan R.; Moore, Sarah A.; Soininen, Sonja; Haapala, Eero A.; Westgate, Kate; Brage, Soren; Agostinete, Ricardo R.; Fernandes, Romulo A.; Lakka, Timo A.. 2021. International journal of environmental research and public health. 18: 5365 A1 Journal article (refereed), original research -
The independent and interactive associations of physical activity intensity and vitamin D status with bone mineral density in prepubertal children: the PANIC Study
Constable, AM; Vlachopoulos, D; Barker, AR; Moore, SA; Soininen, S; Haapala, EA; Väistö, J; Westgate, K; Brage, S; Mähönen, A; Lakka, TA. 2021. Osteoporosis international. 32: 1609-1620 A1 Journal article (refereed), original research -
The trans-ancestral genomic architecture of glycemic traits
Chen, J; Spracklen, CN; Marenne, G; Varshney, A; Corbin, LJ; Luan, J; Willems, SM; Wu, Y; Zhang, X; Horikoshi, M; Boutin, TS; Mägi, R; Waage, J; Li-Gao, R; Chan, KHK; Yao, J; Anasanti, MD; Chu, AY; Claringbould, A; Heikkinen, J; et al. [incl. Kuulasmaa, T; Kuusisto, J; Laakso, M; Lakka, T; Uusitupa, M; Vangipurapu, J]. 2021. Nature genetics. 53: 840-860 A1 Journal article (refereed), original research -
A 2 year physical activity and dietary intervention attenuates the increase in insulin resistance in a general population of children: the PANIC study
Lakka, Timo A; Lintu, Niina; Väistö, Juuso; Viitasalo, Anna; Sallinen, Taisa; Haapala, Eero A; Tompuri, Tuomo T; Soininen, Sonja; Karjalainen, Panu; Schnurr, Theresia M; Mikkonen, Santtu; Atalay, Mustafa; Kilpeläinen, Tuomas O; Laitinen, Tomi; Laaksonen, David E; Savonen, Kai; Brage, Soren; Schwab, Ursula; Jääskeläinen, Jarmo; Lindi, Virpi; Eloranta, Aino-Maija. 2020. Diabetologia. 63: 2270-2281 A1 Journal article (refereed), original research -
An overview on the associations between health behaviors and brain health in children and adolescents with special reference to diet quality
Naveed, Sehrish; Lakka, Timo; Haapala, Eero A. 2020. International journal of environmental research and public health. 17: 953 A2 Review article, Literature review, Systematic review -
Associations between cardiorespiratory fitness, motor competence, and adiposity in children
Haapala, Eero A; Gao, Ying; Lintu, Niina; Väistö, Juuso; Vanhala, Anssi; Tompuri, Tuomo; Lakka, Timo A; Finni, Taija. 2020. Translational sports medicine. 2021; 4: 56-64 A1 Journal article (refereed), original research -
Associations of dietary carbohydrate and fatty acid intakes with cognition among children
Naveed, Sehrish; Venäläinen, Taisa; Eloranta, Aino-Maija; Erkkilä, Arja; Jalkanen, Henna; Lindi, Virpi; Lakka, Timo; Haapala, Eero. 2020. Public health nutrition. 23: 1657-1663 A1 Journal article (refereed), original research -
Child-related and Parental Predictors for Thelarche in a General Population of Girls: The PANIC Study
Savinainen, SE; Viitasalo, A; Sallinen, TM; Jääskeläinen, JES; Lakka, TA. 2020. Pediatric research. 88: 676-680 A1 Journal article (refereed), original research -
Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals
Surendran, Praveen; Feofanova, Elena V; Lahrouchi, Najim; Ntalla, Ioanna; Karthikeyan, Savita; Cook, James; Chen, Lingyan; Mifsud, Borbala; Yao, Chen; Kraja, Aldi T; Cartwright, James H; Hellwege, Jacklyn N; Giri, Ayush; Tragante, Vinicius; Thorleifsson, Gudmar; Liu, Dajiang J; Prins, Bram P; Stewart, Isobel D; Cabrera, Claudia P; Eales, James M; et al. (incl. Stanakova, Alena; Laatikainen, Tiina; Laakso, Markku; Lakka, Timo A). 2020. Nature genetics. 52: 1314-1332 A1 Journal article (refereed), original research -
Effects of a 2-Year Lifestyle Intervention on Cardiorespiratory Fitness in 6-8- Year-Old Children: The PANIC Study
Agbaje, AO; Barker, AR; Eloranta, A-M; Haapala, EA; Lintu, N; Savonen, K; Kilpeläinen, TO; Brage, S; Lakka, TA. 2020. Pediatric exercise science -
Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci
de Las Fuentes, Lisa; Sung, Yun Ju; Noordam, Raymond; Winkler, Thomas; Feitosa, Mary F; Schwander, Karen; Bentley, Amy R; Brown, Michael R; Guo, Xiuqing; Manning, Alisa; Chasman, Daniel I; Aschard, Hugues; Bartz, Traci M; Bielak, Lawrence F; Campbell, Archie; Cheng, Ching-Yu; Dorajoo, Rajkumar; Hartwig, Fernando P; Horimoto, A R V R; Li, Changwei et al [incl. Heikkinen, Sami; Lakka, Timo]. 2020. Molecular psychiatry. 2021; 26: 2111-2125 A1 Journal article (refereed), original research -
Leisure-time cross-country skiing and the risk of venous thromboembolism: A prospective cohort study
Kunutsor, Setor; Lakka, Timo; Kurl, Sudhir; Mäkikallio, Timo; Jae, Sae Young; Laukkanen, Jari. 2020. European journal of preventive cardiology. 2021; 28: 1138-1141 A1 Journal article (refereed), original research -
Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits
Vogelezang, Suzanne; Bradfield, Jonathan P; Ahluwalia, Tarunveer S; Curtin, John A; Lakka, Timo A; Grarup, Niels; Scholz, Markus; van der Most, Peter J; Monnereau, Claire; Stergiakouli, Evie; Heiskala, Anni; Horikoshi, Momoko; Fedko, Iryna O; Vilor-Tejedor, Natalia; Cousminer, Diana L; Standl, Marie; Wang, Carol A; Viikari, Jorma; Geller, Frank; Íñiguez, Carmen; et al. (Incl. Atalay, Mustafa; Lindi, Virpi). 2020. PLoS genetics. 16: e1008718 A1 Journal article (refereed), original research -
Primary hand motor representation areas in healthy children, preadolescents, adolescents, and adults
Säisänen, Laura; Könönen, Mervi; Niskanen, Eini; Lakka, Timo; Lintu, Niina; Vanninen, Ritva; Julkunen, Petro; Määttä, Sara. 2020. Neuroimage. 2021; 228: 117702 A1 Journal article (refereed), original research -
StopDia-hankkeesta vinkkejä terveyden edistämiseen ja hyte-johtamiseen
Tilles-Tirkkonen, Tanja; Männikkö, Reija; Lindström, Jaana; Harjumaa, Marja; Aittola, Kirsikka; Järvelä-Reijonen, Elina; Rantala, Eeva; Martikainen, Janne; Lakka, Timo; Pihlajamäki, Jussi. 2020. Ravitsemusasiantuntija. 6: 4-7 D1 Article in a trade journal -
Suomalaisten lasten ja nuorten ruokaympäristö ja toimenpide-ehdotukset sen kehittämiseen terveyttä edistäväksi
Rantala, Eeva; Martikainen, Janne; Lakka, Timo; Vanhatalo, Saara; Heiskanen, Jari; Väistö, Juuso; Leväsluoto, Johanna; Hassinen, Maija; Eloranta, Aino-Maija; Sigfrids, Anton; Harjumaa, Marja. 2020. Valtioneuvoston selvitys- ja tutkimustoiminnan julkaisusarja. . D4 Published development or research report or study -
The effects of a 2-year physical activity and dietary intervention on plasma lipid concentrations in children: the PANIC Study
Eloranta, Aino-Maija; Sallinen, Taisa; Viitasalo, Anna; Lintu, Niina; Väistö, Juuso; Jalkanen, Henna; Tompuri, Tuomo T; Soininen, Sonja; Haapala, Eero A; Kiiskinen, Sanna; Schnurr, Theresia M; Kilpeläinen, Tuomas O; Mikkonen, Santtu; Savonen, Kai; Atalay, Mustafa; Brage, Soren; Laaksonen, David E; Lindi, Virpi; Ågren, Jyrki; Schwab, Ursula; et al. [incl. Jääskeläinen, Jarmo; Lakka, Timo]. 2020. European journal of nutrition. 2021; 60: 425-434 A1 Journal article (refereed), original research -
A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure
Sung, Yun Ju; de Las Fuentes, Lisa; Winkler, Thomas W; Chasman, Daniel I; Bentley, Amy R; Kraja, Aldi T; Ntalla, Ioanna; Warren, Helen R; Guo, Xiuqing; Schwander, Karen; Manning, Alisa K; Brown, Michael R; Aschard, Hugues; Feitosa, Mary F; Franceschini, Nora; Lu, Yingchang; et al. (incl. Heikkinen, Sami; Kuusisto, Johanna; Laakso, Markku; Stancáková, Alena; Lakka, Timo A). 2019. Human molecular genetics. 28: 2615-2633 A1 Journal article (refereed), original research -
A trans-ancestral meta-analysis of genome-wide association studies reveals loci associated with childhood obesity
Bradfield, Jonathan P; Vogelezang, Suzanne; Felix, Janine F; Chesi, Alessandra; Helgeland, Øyvind; Horikoshi, Momoko; Karhunen, Ville; Lowry, Estelle; Cousminer, Diana L; Ahluwalia, Tarunveer S; Thiering, Elisabeth; Boh, Eileen Tai-Hui; Zafarmand, Mohammad H; Vilor-Tejedor, Natalia; Wang, Carol A; Joro, Raimo; Chen, Zhanghua; Gauderman, William J; Pitkänen, Niina; Parra, Esteban J; et al. (incl. Atalay, Mustafa; Lakka, Timo A; Lindi, Virpi). 2019. Human molecular genetics. 28: 3327-3338 A1 Journal article (refereed), original research -
Abdominal adiposity and cardiometabolic risk factors in children and adolescents: a Mendelian randomization analysis
Viitasalo, A; Schnurr, TM; Pitkänen, N; Hollensted, M; Nielsen, TRH; Pahkala, K; Atalay, M; Lind, MV; Heikkinen, S; Frithioff-Bøjsøe, C; Fonvig, CE; Grarup, N; Kähönen, M; Carrasquilla, GD; Larnkjaer, A; Pedersen, O; Michaelsen, KF; Lakka, TA; Holm, JC; Lehtimäki, T; et al.. 2019. American journal of clinical nutrition. 110: 1079-1087 A1 Journal article (refereed), original research -
Adiposity Criteria in Assessing Increased Cardiometabolic Risk in Prepubertal Children
Tompuri, Tuomo Tapani; Jaaskelainen, Jarmo; Lindi, Virpi; Laaksonen, David Elliot; Eloranta, Aino-Maija; Viitasalo, Anna; Laitinen, Tomi; Lakka, Limo Antero. 2019. Frontiers in endocrinology. 10: 410 A1 Journal article (refereed), original research -
Associations of Cardiorespiratory Fitness and Adiposity With Arterial Stiffness and Arterial Dilatation Capacity in Response to a Bout of Exercise in Children
Agbaje, Andrew O; Haapala, Eero A; Lintu, Niina; Viitasalo, Anna; Vaisto, Juuso; Khan, Sohaib; Veijalainen, Aapo; Tompuri, Tuomo; Laitinen, Tomi; Lakka, Timo A. 2019. Pediatric exercise science. 31: 238-247 A1 Journal article (refereed), original research -
Associations of IGF-1 and Adrenal Androgens with Cognition in Childhood
Mäntyselkä, A; Haapala, EA; Lindi, V; Häkkinen, MR; Auriola, S; Jääskeläinen, J; Lakka, TA. 2019. Hormone research in paediatrics. 91: 329-335 A1 Journal article (refereed), original research -
Associations of cardiometabolic risk factors with heart rate variability in 6-8-year-old children: the PANIC Study
Leppänen, MH; Haapala, EA; Veijalainen, A; Seppälä, S; Oliveira, RS; Lintu, N; Laitinen, T; Tarvainen, MP; Lakka, TA. 2019. Pediatric diabetes. 2020; 21: 251-258 A1 Journal article (refereed), original research -
Associations of physical activity, sedentary time, and cardiorespiratory fitness with heart rate variability in 6- to 9-year-old children: the PANIC study
Veijalainen, A; Haapala, EA; Väistö, J; Leppänen, MH; Lintu, N; Tompuri, T; Seppälä, S; Ekelund, U; Tarvainen, MP; Westgate, K; Brage, S; Lakka, TA. 2019. European journal of applied physiology. 119: 2487-2498 A1 Journal article (refereed), original research -
Cardiorespiratory Fitness, Physical Activity, and Insulin Resistance in Children
Haapala, EA; Wiklund, P; Lintu, N; Tompuri, T; Väistö, J; Finni, T; Tarkka, IM; Kemppainen. T; Barker, AR; Ekelund, U; Brage, S; Lakka, TA. 2019. Medicine and science in sports and exercise. 2020; 52: 1144-1152 A1 Journal article (refereed), original research -
Cross-country skiing and the risk of acute myocardial infarction: A prospective cohort study
Laukkanen, JA; Lakka, TA; Ogunjesa, BA; Kurl, S; Kunutsor, SK. 2019. European journal of preventive cardiology. [First Published August 19, 2019]: 1-4 A1 Journal article (refereed), original research -
Digitally supported program for type 2 diabetes risk identification and risk reduction in real-world setting: protocol for the StopDia model and randomized controlled trial
Pihlajamäki, J; Männikkö, R; Tilles-Tirkkonen, T; Karhunen, L; Kolehmainen, M; Schwab, U; Lintu, N; Paananen, J; Järvenpää, R; Harjumaa, M; Martikainen, J; Kohl, J; Poutanen, K; Ermes, M; Absetz, P; Lindström, J; Lakka, TA. 2019. Bmc public health. 19: 255 A1 Journal article (refereed), original research -
Eating Competence Is Associated with Lower Prevalence of Obesity and Better Insulin Sensitivity in Finnish Adults with Increased Risk for Type 2 Diabetes: The StopDia Study
Tilles-Tirkkonen, Tanja; Aittola, Kirsikka; Männikkö, Reija; Absetz, Pilvikki; Kolehmainen, Marjukka; Schwab, Ursula; Lindström, Jaana; Lakka, Timo; Pihlajamäki, Jussi; Karhunen, Leila. 2019. Nutrients. 2020; 12: 104 A1 Journal article (refereed), original research -
Functional and structural asymmetry in primary motor cortex in Asperger syndrome: a navigated TMS and imaging study
Säisänen, L; Määttä, S; Julkunen, P; Niskanen, E; Kallioniemi, E; Gröhn, H; Kemppainen, S; Lakka, TA; Lintu, N; Eloranta, AM; Vanninen, R; Makkonen, I; Könönen, M. 2019. Brain topography. 32: 504-518 A1 Journal article (refereed), original research -
Fyysinen aktiivisuus ja ravitsemus lasten terveyden edistämisessä - tavoitteena lihavuuden, tyypin 2 diabeteksen ja valtimotautien ehkäisy
Lakka, Timo A; Talvia, Sanna; Sääkslahti, Arja; Haapala, Eero. Teoksessa: Pietilä, Anna-Maija; Terkamo-Moisio, Anja(toim.) , 2019. Näkökulmia terveyteen ja sen edistämiseen. s. 133-166. Itä-Suomen yliopisto B2 Book section -
GWAS on longitudinal growth traits reveals different genetic factors influencing infant, child, and adult BMI
Alves, AC; De Silva, NMG; Karhunen, V; Sovio, U; Das, S; Rob Taal, H; Warrington, NM; Lewin, AM; Kaakinen, M; Cousminer, DL; Thiering, E; Timpson, NJ; Bond, TA; Lowry, E; Brown, CD; Estivill, X; Lindi, V; Bradfield, JP; Geller, F; Speed, D; et al. for BIOS Consortium [incl. Lakka, TA]. 2019. Science advances. 5: eaaw3095 A1 Journal article (refereed), original research -
Genetic predisposition to higher body fat yet lower cardiometabolic risk in children and adolescents
Viitasalo, Anna; Schnurr, Theresia M.; Pitkanen, Niina; Hollensted, Mette; Nielsen, Tenna R. H.; Pahkala, Katja; Lintu, Niina; Lind, Mads V.; Atalay, Mustafa; Frithioff-Bojsoe, Christine; Fonvig, Cilius E.; Grarup, Niels; Kahonen, Mika; Larnkjaer, Anni; Pedersen, Oluf; Holm, Jens-Christian; Michaelsen, Kim F.; Lakka, Timo A.; Lehtimaki, Terho; Raitakari, Olli; et al.. 2019. International journal of obesity. 43: 2007-2016 A1 Journal article (refereed), original research -
Hyvinvoinnin ja osallisuuden edistäminen vaatii uusia vaikuttavia keinoja
Mäki-Opas, Tomi; Tilles-Tirkkonen, Tanja; Saari, Eveliina; Järvenpää, Riia; Lindström, Jaan; Karhunen, Leila; Kurki, Marjo; Pihlajamäki, Jussi; Niemi, Anna-Maija; Laaksonen, Linda Maria; Korkiakangas, Eveliina; Lakka, Timo; Vaarama, Marja; Laitinen, Jaana. 2019. Policy Brief / SA. : 1-12 E1 Popularised article, newspaper article -
Integrative analysis of gene expression, DNA methylation, physiological traits, and genetic variation in human skeletal muscle
Taylor, DL; Jackson, AU; Narisu, N; Hemani, G; Erdos, MR; Chines, PS; Swift, A; Idol, J; Didion, JP; Welch, RP; Kinnunen, L; Saramies, J; Lakka, TA; Laakso, M; Tuomilehto, J; Parker, SCJ; Koistinen, HA; Davey Smith, G; Boehnke, M; Scott, LJ; et al.. 2019. Proceedings of the National Academy of Sciences of the United States of America. 116: 10883-10888 A1 Journal article (refereed), original research -
Longitudinal Associations of Fitness, Motor Competence, and Adiposity with Cognition
Haapala, Eero A; Lintu, Niina; Väistö, Juuso; Tompuri, Tuomo; Soininen, Sonja; Viitasalo, Anna; Eloranta, Aino-Maija; Venäläinen, Taisa; Sääkslahti, Arja; Laitinen, Tomi; Lakka, Timo A. 2019. Medicine and science in sports and exercise. 51: 465-471 A1 Journal article (refereed), original research -
Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors
Warrington, NM; Beaumont, RN; Horikoshi, M; Day, FR; Helgeland, Ø; Laurin, C; Bacelis, J; Peng, S; Hao, K; Feenstra, B; Wood, AR; Mahajan, A; Tyrrell, J; Robertson, NR; Rayner, NW et al. (ncl. Joro, R; Atalay, M; Eloranta, AM; Lakka, TA). 2019. Nature genetics. 51: 804-814 A1 Journal article (refereed), original research -
Maturation changes the excitability and effective connectivity of the frontal lobe: A developmental TMS-EEG study
Määttä, S; Säisänen, L; Kallioniemi, E; Lakka, TA; Lintu, N; Haapala, EA; Koskenkorva, P; Niskanen, E; Ferreri, F; Könönen, M. 2019. Human brain mapping. 40: 2320-2335 A1 Journal article (refereed), original research -
Multi-Ancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions
de Vries, PS; Brown, MR; Bentley, AR; Sung, YJ; Winkler, TW; Ntalla, I; Schwander, K; Kraja, AT; Guo, X; Franceschini, N; Cheng, CY; Sim, X; Vojinovic, D; Huffman, JE; Musani, SK; Li, C; Feitosa, MF; Richard, MA; Noordam, R; Aschard, H; et al. (Incl. Kuusisto, Johanna; Laakso, Markku; Lakka, Timo; Heikkinen, Sami). 2019. American journal of epidemiology. 188: 1033-1054 A1 Journal article (refereed), original research -
Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids
Bentley, AR; Sung, YJ; Brown, MR; Winkler, TW; Kraja, AT; Ntalla, I; Schwander, K; Chasman, DI; Lim, E; Deng, X; Guo, X; Liu, J; Lu, Y; Cheng, CY; Sim, X; Vojinovic, D; Lakka, TA; Heikkinen, S; Kuusisto, J; Laakso, M; et al. (incl. Laakso, Markku; Heikkinen, Sami; Kuusisto, Johanna; Lakka, Timo; Rauramaa, Rainer). 2019. Nature genetics. 51: 636-648 A1 Journal article (refereed), original research -
Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity
Kilpeläinen, TO; Bentley, AR; Noordam, R; Sung, YJ; Schwander, K; Winkler, TW; Jakupovic, H; Chasman, DI; Manning, A; Ntalla, I; Aschard, H; Brown, MR; de Las Fuentes, L; Franceschini, N; Guo, X; Vojinovic, D; Aslibekyan, S; Feitosa, MF; Kho, M; Musani, SK; et al. [Incl. Lakka, Timo; Heikkinen, Sami; Kuusisto, Johanna; Laakso, Markku]. 2019. Nature communications. 10: 376 A1 Journal article (refereed), original research -
Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution
Justice, AE; Karaderi, T; Highland, HM; Young, KL; Graff, M; Lu, Y; Turcot, V; Auer, PL; Fine, RS; Guo, X; Schurmann, C; Lempradl, A; Marouli, E; Mahajan, A; Winkler, TW; Locke, AE; Medina-Gomez, C; Esko, T; Vedantam, S; Giri, A; Lo, KS; et al. (Incl. Kuusisto, Johanna; Laakso, Markku; Lakko, Timo; Uusitupa, Matti; Vanhala, Mauno). 2019. Nature genetics. 51: 452-469 A1 Journal article (refereed), original research -
The Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia: design, results and future prospects
Middeldorp, Christel M; Felix, Janine F; Mahajan, Anubha; EArly Genetics Lifecourse Epidemiology (EAGLE) consortium; Early Growth Genetics (EGG) consortium (Incl Atalay, Mustafa; Lakka, Timo A); McCarthy, Mark I. 2019. European journal of epidemiology. 34: 279-300 A1 Journal article (refereed), original research -
Analysis by LC-MS/MS of endogenous steroids from human serum, plasma, endometrium and endometriotic tissue
Häkkinen, MR; Heinosalo, T; Saarinen, N; Linnanen, T; Voutilainen, R; Lakka, T; Jääskeläinen, J; Poutanen, M; Auriola, S. 2018. Journal of pharmaceutical and biomedical analysis. 152: 165-172 A1 Journal article (refereed), original research -
Associations of Dehydroepiandrosterone Sulfate with Cardiometabolic Risk Factors in Prepubertal Children
Mäntyselkä, A; Lindi, V; Viitasalo, A; Eloranta, AM; Ågren, J; Väisänen, S; Voutilainen, R; Laitinen, T; Lakka, TA; Jääskeläinen, J. 2018. Journal of clinical endocrinology and metabolism. 103: 2592-2600 A1 Journal article (refereed), original research -
Associations of Genetic Susceptibility to Alzheimer's Disease with Adiposity and Cardiometabolic Risk Factors among Children in a 2-Year Follow-up Study
Haapala, Eero A; Paananen, Jussi; Hiltunen, Mikko; Lakka, Timo A. 2018. Journal of Alzheimer's disease. 64: 587-595 A1 Journal article (refereed), original research -
Associations of cardiorespiratory fitness and adiposity with arterial stiffness and arterial dilation capacity in response to exercise in children
Agbaje, AO; Haapala, EA; Lintu, N; Viitasalo, A; Väistö, J; Khan, S; Veijalainen, A; Tompuri, T; Laitinen, T; Lakka, TA. 2018. Pediatric exercise science -
Birth weight is associated with dietary factors at the age of 6-8 years: the Physical Activity and Nutrition in Children (PANIC) study
Eloranta, AM; Jääskeläinen, J; Venäläinen, T; Jalkanen, H; Kiiskinen, S; Mäntyselkä, A; Schwab, U; Lindi, V; Lakka, TA. 2018. Public health nutrition. 21: 1278-1285 A1 Journal article (refereed), original research -
Body fat mass, lean body mass and associated biomarkers as determinants of bone mineral density in children 6-8 years of age - The Physical Activity and Nutrition in Children (PANIC) study
Soininen, Sonja; Sidoroff, Virpi; Lindi, Virpi; Mahonen, Anitta; Kröger, Liisa; Kröger, Heikki; Jääskeläinen, Jarmo; Atalay, Mustafa; Laaksonen, David E; Laitinen, Tomi; Lakka, Timo A. 2018. Bone. 108: 106-114 A1 Journal article (refereed), original research -
Consortium-based genome-wide meta-analysis for childhood dental caries traits
Haworth, S; Shungin, D; van der Tas, JT; Vucic, S; Medina-Gomez, C; Yakimov, V; Feenstra, B; Shaffer, JR; Lee, MK; Standl, M; Thiering, E; Wang, C; Bønnelykke, K; Waage, J; Eyrich Jessen, L; Nørrisgaard, PE; Joro, R; Seppälä, I; Raitakari, O; Dudding, T; et al. [Incl Lakka, T; Eloranta, A-M; Vierola, A]. 2018. Human molecular genetics. 27: 3113-3127 A1 Journal article (refereed), original research -
Development of corticospinal motor excitability and cortical silent period from mid-childhood to adulthood - a navigated TMS study
Säisänen, Laura; Julkunen, Petro; Lakka, Timo; Lindi, Virpi; Könönen, Mervi; Määttä; Sara. 2018. Neurophysiologie clinique-clinical neurophysiology. 48: 65-75 A1 Journal article (refereed), original research -
Health-related correlates of psychological well-being among girls and boys 6-8 years of age: The Physical Activity and Nutrition in Children study
Ikävalko, T; Lehto, S; Lintu, N; Väistö, J; Eloranta, AM; Haapala, EA; Vierola, A; Myllykangas, R; Tuomilehto, H; Brage, S; Pahkala, R; Närhi, M; Lakka, TA. 2018. Journal of paediatrics and child health. 54: 506-509 A1 Journal article (refereed), original research -
Interactions between genetic variation and cellular environment in skeletal muscle gene expression
Taylor, DL; Knowles, DA; Scott, LJ; Ramirez, AH; Casale, FP; Wolford, BN; Guan, L; Varshney, A; Albanus, RD; Parker, SC; Narisu, N; Chines, PS; Erdos, MR; Welch, RP; Kinnunen, L; Saramies, J; Sundvall, J; Lakka, TA; Laakso, M; Tuomilehto, J; et al.. 2018. PLoS ONE. 13: e0195788 A1 Journal article (refereed), original research -
Kasvu, sukupuolinen kypsyminen ja kehitys sekä niiden merkitys liikuntatieteissä
Savinainen, Saija; Lakka, Timo A; Vlachopoulos, Dimitris; Sääkslahti, Arja; Helajärvi, Harri; Ihalainen, Johanna K; Finni, Taija; Haapala, Eero A. 2018. Liikunta ja tiede. 55: 23-29 D1 Article in a trade journal -
Lasten ja nuorten kestävyyskunto
Lintu, Niina; Joensuu, Laura; Barker, Alan; Sansum, Kate; Lakka, Timo A; Huotari, Pertti; Haapala, Eero A. 2018. Liikunta ja tiede. 55: 36-43 D1 Article in a trade journal -
Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects
Medina-Gomez, C; Kemp, JP; Trajanoska, K; Luan, J; Chesi, A; Ahluwalia, TS; Mook-Kanamori, DO; Ham, A; Hartwig, FP; Evans, DS; Joro, R; Nedeljkovic, I; Zheng, HF; Zhu, K; Atalay, M; Liu, CT; Nethander, M; Broer, L; Porleifsson, G; Mullin, BH et al. [incl. Lakka, T]. 2018. American journal of human genetics. 102: 88-102 A1 Journal article (refereed), original research -
Longitudinal associations of physical activity and sedentary time with cardiometabolic risk factors in children
Väistö, Juuso; Haapala, Eero A; Viitasalo, Anna; Schnurr, Theresia M; Kilpeläinen, Tuomas O; Karjalainen, Panu; Westgate, Kate; Lakka, Hanna-Maaria; Laaksonen, David E; Ekelund, Ulf; Brage, Søren; Lakka, Timo A. 2018. Scandinavian journal of medicine and science in sports. 2019; 29: 113-123 A1 Journal article (refereed), original research -
Mediating effects of motor performance, cardiorespiratory fitness, physical activity, and sedentary behaviour on the associations of adiposity and other cardiometabolic risk factors with academic achievement in children
Haapala, Eero A; Lintu, Niina; Eloranta, Aino-Maija; Venäläinen, Taisa; Poikkeus, Anna-Maija; Ahonen, Timo; Lindi, Virpi; Lakka, Timo A. 2018. Journal of sports sciences. 36: 2296-2303 A1 Journal article (refereed), original research -
Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries
Feitosa, MF; Kraja, AT; Chasman, DI; Sung, YJ; Winkler, TW; Ntalla, I; Guo, X; Franceschini, N; Cheng, CY; Sim, X; Vojinovic, D; Marten, J; Musani, SK; Li, C; Bentley, AR; Brown, MR; Schwander, K; Richard, MA; Noordam, R; Aschard, H; et al. (incl. Laakso, Markku; Heikkinen, Sami; Kuusisto, Johanna; Lakka, Timo; Yaluri, Alena). 2018. PLoS ONE. 13: e0198166 A1 Journal article (refereed), original research -
Peak oxygen uptake cut-points to identify children at increased cardiometabolic risk - The PANIC Study
Agbaje, Andrewe O; Haapala, Eero A; Lintu, Nina; Viitasalo, Anna; Barker, Alan R; Takken, Tim; Tompuri, Tuomo; Lindi, Virpi; Lakka, Timo A. 2018. Scandinavian journal of medicine and science in sports. 2019; 29: 16-24 A1 Journal article (refereed), original research -
Serum 25-Hydroxyvitamin D, Plasma Lipids, and Associated Gene Variants in Prepubertal Children
Soininen, Sonja; Eloranta, Aino-Maija; Viitasalo, Anna; Dion, Geneviève; Erkkilä, Arja; Sidoroff, Virpi; Lindi, Virpi; Mahonen, Anitta; Lakka, Timo A. 2018. Journal of clinical endocrinology and metabolism. 103: 2670-2679 A1 Journal article (refereed), original research -
Simultaneous analysis by LC-MS/MS of 22 ketosteroids with hydroxylamine derivatization and underivatized estradiol from human plasma, serum and prostate tissue
Häkkinen, Merja R; Murtola, Teemu; Voutilainen, Raimo; Poutanen, Matti; Linnanen, Tero; Koskivuori, Johanna; Lakka, Timo; Jääskeläinen, Jarmo; Auriola, Seppo. 2018. Journal of pharmaceutical and biomedical analysis. 2019; 164: 642-652 A1 Journal article (refereed), original research -
Uric acid level as a risk factor for cardiovascular and all-cause mortality in middle-aged men. A prospective cohort study (in Russian)
Niskanen, LK; Laaksonen, DE; Nyyssonen, K; Alfthan, G; Lakka, H-M; Lakka, TA; Salonen, J. 2018. Kardiologiâ v Belarusi. 10: 440-445 A1 Journal article (refereed), original research -
A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk
Manning A, Highland HM, Gasser J, Sim X, Tukiainen T, Fontanillas P, Grarup N, Rivas MA, Mahajan A, Locke AE, Cingolani P, Pers TH, Viñuela A, Brown AA, Wu Y, Flannick J, Fuchsberger C, Gamazon ER, Gaulton KJ, Im HK et al. (incl. Lakka Timo, Kuulasmaa Teemu, Laakso Markku, Uusitupa Matti). 2017. Diabetes. 66: 2019-2032 A1 Journal article (refereed), original research -
Associations of Objectively Measured Physical Activity and Sedentary Time With Arterial Stiffness in Pre-pubertal Children
Haapala Eero, Väistö Juuso, Veijalainen Aapo, Lintu Niina, Wiklund P,etri Westgate Kate, Ekelund Ulf, Lindi Virpi, Brage Soren, Lakka Timo A. 2017. Pediatric exercise science. 29: 326-335 A1 Journal article (refereed), original research -
Associations of lifestyle factors with serum dehydroepiandrosterone sulfate and insulin-like growth factor-1 concentration in prepubertal children
Mäntyselkä A, Jääskeläinen J, Eloranta AM, Väistö J, Voutilainen R, Ong K, Brage S, Lakka TA, Lindi V. 2017. Clinical endocrinology. 2018; 88: 234-242 A1 Journal article (refereed), original research -
Determinants for craniofacial pains in children 6-8 years of age: the PANIC study
Vierola A, Suominen AL, Eloranta AM, Lintu N, Ikävalko T, Närhi M, Lakka T. 2017. Acta odontologica scandinavica. 75: 453-460 A1 Journal article (refereed), original research -
Development of cortical motor circuits between childhood and adulthood: A navigated TMS-HdEEG study
Määttä S, Könönen M, Kallioniemi E, Lakka T, Lintu N, Lindi V, Ferreri F, Ponzo D, Säisänen L. 2017. Human brain mapping. 38: 2599-2615 A1 Journal article (refereed), original research -
Eating behaviour is associated with eating frequency and food consumption in 6-8 year-old children: The Physical Activity and Nutrition in Children (PANIC) study
Jalkanen H, Lindi V, Schwab U, Kiiskinen S, Venäläinen T, Karhunen L, Lakka TA, Eloranta AM. 2017. Appetite. 114: 28-37 A1 Journal article (refereed), original research -
Exome-wide association study of plasma lipids in >300,000 individuals
Liu DJ, Peloso GM, Yu H, Butterworth AS, Wang X, Mahajan A, Saleheen D, Emdin C, Alam D, Alves AC, Amouyel P, Di Angelantonio E, Arveiler D, Assimes TL, Auer PL, Baber U, Ballantyne CM, Bang LE, Benn M, Bis JC et al.. 2017. Nature genetics. 49: 1758-1766 A1 Journal article (refereed), original research -
Genetic predisposition to adiposity is associated with increased objectively assessed sedentary time in young children
Schnurr TM, Viitasalo A, Eloranta AM, Damsgaard CT, Mahendran Y, Have CT, Väistö J, Hjorth MF, Christensen LB, Brage S, Atalay M, Lyytikäinen LP, Lindi V, Lakka T, Michaelsen KF, Kilpeläinen TO, Hansen T. 2017. International journal of obesity. 42: 111-114 A1 Journal article (refereed), original research -
Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits
Justice Anne E, Winkler Thomas W, Feitosa Mary F, Graff Misa, Fisher Virginia A, Young Kristin, Barata Llilda, Deng Xuan, Czajkowski Jacek, Hadley David, Ngwa Julius S, Ahluwalia Tarunveer S, Chu Audrey Y, Heard-Costa Nancy L, Lim Elise, Perez Jeremiah, Eicher John D, Kutalik Zoltan, Xue Luting, Mahajan Anubha et al.. 2017. Nature communications. 8: 14977 A1 Journal article (refereed), original research -
Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults
Graff M, Scott RA, Justice AE, Young KL, Feitosa MF, Barata L, Winkler TW, Chu AY, Mahajan A, Hadley D, Xue L, Workalemahu T, Heard-Costa NL, den Hoed M, Ahluwalia TS, Qi Q, Ngwa JS, Renström F, Quaye L, Eicher JD et al.. 2017. PLoS genetics. 13: e1006528 A1 Journal article (refereed), original research -
High Leisure-Time Physical Activity Is Associated With Reduced Risk of Sudden Cardiac Death Among Men With Low Cardiorespiratory Fitness
Hagnäs, MJ; Lakka, TA; Mäkikallio, TH; Kurl, S; Savonen, K; Rauramaa, R; Laukkanen, JA. 2017. Canadian journal of cardiology. 2018; 34: 288-294 A1 Journal article (refereed), original research -
Is there a duty to participate in a health research? A viewpoint of children 6-8 years of age and their parents
Länsimies H, Halkoaho A, Pietilä A-M, Lintu N, Kangasniemi M, Eloranta A-M, Viitasalo A, Lakka TA. 2017. International diabetes nursing. 13: 49-54 A1 Journal article (refereed), original research -
Maternal and fetal genetic contribution to gestational weight gain
Warrington NM, Richmond R, Fenstra B, Myhre R, Gaillard R, Paternoster L, Wang CA, Beaumont RN, Das S, Murcia M, Barton SJ, Espinosa A, Thiering E, Atalay M, Pitkänen N, Ntalla I, Jonsson AE, Freathy R, Karhunen V, Tiesler CMT et al. for the Early Growth Genetics (EGG) consortium. 2017. International journal of obesity. 42: 775-784 A1 Journal article (refereed), original research -
New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals
Kraja Aldi T, Cook James P, Warren Helen R, Surendran Praveen, Liu Chunyu, Evangelou Evangelos, Mannig Alisa K, Grarup Niels, Drenos Fotios, Sim Xueling, Smith Albert Vernon, Amin Najaf, Blakemore Alexandra I F, Bork-Jensen Jette, Brandslund Ivan, Farmaki Aliki-Eleni, Fava Cristiano, Ferreira Teresa, Herzig Karl-Heinz, Giri Ayush et al.. 2017. Circulation: cardiovascular genetics. 10: e001778 A1 Journal article (refereed), original research -
Physical activity, sedentary behaviour, and socioeconomic status among Finnish girls and boys aged 6 - 8 years
Lampinen Eeva-Kaarina, Eloranta Aino-Maija, Haapala Eero A, Lindi Virpi, Väistö Juuso, Lintu Niina, Karjalainen Panu, Kukkonen-Harjula Katriina, Laaksonen David, Lakka Timo A. 2017. European journal of sport science. 17: 462-472 A1 Journal article (refereed), original research -
Predictors of sleep disordered breathing in children: the PANIC study
Ikävalko, T; Närhi, M; Eloranta, AM; Lintu, N; Myllykangas, R; Vierola, A; Tuomilehto, H; Lakka, T; Pahkala, R. 2017. European journal of orthodontics. 2018; 40: 268-272 A1 Journal article (refereed), original research -
Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity
Turcot V, Lu Y, Highland HM, Schurmann C, Justice AE, Fine RS, Bradfield JP, Esko T, Giri A, Graff M, Guo X, Hendricks AE, Karaderi T, Lempradl A, Locke AE, Mahajan A, Marouli E, Sivapalaratnam S, Young KL, Alfred T et al. (incl. Laakso Markku, Lakka Timo, Uusitupa Matti). 2017. Nature genetics. 50; 2018: 26-41 A1 Journal article (refereed), original research -
Rare and low-frequency coding variants alter human adult height
Marouli Eirini, Graff Mariaelisa, Medina-Gomez Carolina, Sin Lo Ken, Wood Andrew R, Kjaer Troels R, Fine Rebecca S, Lu Yingchang, Schurmann Claudia, Highland Heather M, Rüeger Sina, Thorleifsson Gudmar, Justice Anne E, Lamparter David, Stirrups Kathleen E, Turcot Valérie, Young Kristin L, Winkler Thomas W, Esko Tõnu, Karaderi Tugce et al. (incl Kuusisto Johanna, Laakso Markku, Lakka Timo A). 2017. Nature. 542: 186-190 A1 Journal article (refereed), original research -
Relation of oxygen uptake to work rate in prepubertal healthy children - reference for VO2/W-slope and effect on cardiorespiratory fitness assessment
Tompuri, Tuomo; Lintu, Niina; Laitinen, Tomi; Lakka, Timo A. 2017. Clinical physiology and functional imaging. 2018; 38: 645-651 A1 Journal article (refereed), original research -
Vähäinen fyysinen aktiivisuus ja runsas fyysinen passiivisuus ovat yhteydessä 6-8-vuotiaiden lasten ylipainoon
Haapala Eero A, Väistö Juuso, Lintu Niina, Eloranta Aino-Maija, Lindi Virpi, Lakka Timo A. 2017. Liikunta ja tiede. 54: 106-112 A1 Journal article (refereed), original research -
A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape
Ried JS, Jeff M J, Chu AY, Bragg-Gresham JL, van Dongen J, Huffman JE, Ahluwalia TS, Cadby G, Eklund N, Eriksson J, Esko T, Feitosa MF, Goel A, Gorski M, Hayward C, Heard-Costa NL, Jackson AU, Jokinen E, Kanoni S, Kristiansson K et al. 2016. Nature communications. 7: 13357 A1 Journal article (refereed), original research -
Adiposity, physical activity and neuromuscular performance in children
Haapala Eero A, Vaisto, Juuso, Lintu Niina, Tompuri Tuomo, Brage Soren, Westgate Kate, Ekelund Ulf, Lampinen Eeva-Kaarina, Saakslahti Arja, Lindi Virpi, Lakka Timo A. 2016. Journal of sports sciences. 34: 1699-706 A1 Journal article (refereed), original research -
Association of MBOAT7 gene variant with plasma ALT levels in children: The PANIC study
Viitasalo A, Eloranta A-M, Atalay M, Romeo S, Pihlajamäki J, Lakka TA. 2016. Pediatric research. 80: 651-655 A1 Journal article (refereed), original research -
Associations of Sedentary Behavior, Physical Activity, Cardiorespiratory Fitness, and Body Fat Content With Pain Conditions in Children: The Physical Activity and Nutrition in Children Study
Vierola Anu, Suominen Anna Liisa, Lindi Virpi, Viitasalo Anna, Ikävalko Tiina, Lintu Niina, Väistö Juuso, Kellokoski Jari, Närhi Matti, Lakka Timo A. 2016. Journal of pain. 17: 845-853 A1 Journal article (refereed), original research -
Associations of TM6SF2 167K allele with liver enzymes and lipid profile in children: the PANIC Study
Viitasalo Anna, Pihlajamäki Jussi, Paananen Jussi, Atalay Mustafa, Lindi Virpi, Lakka Timo A. 2016. Pediatric research. 79: 684-688 A1 Journal article (refereed), original research -
Cardiorespiratory fitness and exercise-induced ST segment depression in assessing the risk of sudden cardiac death in men
Hagnäs MJ, Lakka TA, Kurl S, Rauramaa R, Mäkikallio TH, Savonen K, Laukkanen JA. 2016. Heart. 103: 383-389 A1 Journal article (refereed), original research -
Comparison between parameters from maximal cycle ergometer test first without respiratory gas analysis and thereafter with respiratory gas analysis among healthy prepubertal children
Tompuri Tuomo T, Lintu Niina, Soininen Sonja, Laitinen Tomi, Lakka Timo A. 2016. Applied physiology nutrition and metabolism-physiologie appliquee nutrition et metabolisme. 41: 624-630 A1 Journal article (refereed), original research -
Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study
Winkler Thomas W, Justice Anne E, Graff Mariaelisa, Barata Llilda, Feitosa Mary F, Chu Su, Czajkowski Jacek, Esko Tõnu, Fall Tove, Kilpeläinen Tuomas O, Lu Yingchang, Mägi Reedik, Mihailov Evelin, Pers Tune H, Rüeger Sina, Teumer Alexander, Ehret Georg B, Ferreira Teresa, Heard-Costa Nancy L, Karjalainen Juha et al. 2016. PLoS genetics. 12: e1006166 A1 Journal article (refereed), original research -
Cross-sectional associations of objectively-measured physical activity and sedentary time with body composition and cardiorespiratory fitness in mid-childhood: the PANIC study
Collings Paul J, Westgate Kate, Väistö Juuso, Wijndaele Katrien, Atkin Andrew J, Haapala Eero A, Lintu Niina, Laitinen Tomi, Ekelund Ulf, Brage Soren, Lakka Timo A. 2016. Sports medicine. [Epub ahead of print 24 Aug 2016]: 1-12 A1 Journal article (refereed), original research -
Determinants of cardiorespiratory fitness in a population sample of girls and boys aged 6-8 years
Lintu Niina, Savonen Kai, Viitasalo Anna, Tompuri Timo, Paananen Jussi, Tarvainen Mika P, Lakka Timo. 2016. Journal of physical activity and health. [epub ahead of print]: 1-22 A1 Journal article (refereed), original research -
Determinants of serum 25-hydroxyvitamin D concentration in Finnish children: the Physical Activity and Nutrition in Children (PANIC) study
Soininen Sonja, Eloranta Aino-Maija, Lindi Virpi, Venäläinen Taisa, Zaproudina Nina, Mahonen Anitta, Lakka Timo A. 2016. British journal of nutrition. 115: 1080-1091 A1 Journal article (refereed), original research -
Diet quality and academic achievement: a prospective study among primary school children
Haapala Eero A, Eloranta Aino-Maija, Venäläinen Taisa, Jalkanen Henna, Poikkeus Anna-Maija, Ahonen Timo, Lindi Virpi, Lakka Timo A. 2016. European journal of nutrition. 56: 2299-2308 A1 Journal article (refereed), original research -
Dietary quality indices in relation to cardiometabolic risk among Finnish children aged 6-8 years - The PANIC study
Eloranta Aino-Maija, Schwab Ursula, Venäläinen Taisa, Kiiskinen Sanna, Lakka HM, Laaksonen David E, Lakka Timo A, Lindi Virpi. 2016. Nutrition metabolism and cardiovascular diseases. 26: 833-841 A1 Journal article (refereed), original research -
Effect of a 2-y dietary and physical activity intervention on plasma fatty acid composition and estimated desaturase and elongase activities in children: the Physical Activity and Nutrition in Children Study
Venäläinen Taisa M, Viitasalo Anna M, Schwab Ursula S, Eloranta Aino-Maija, Haapala Eero A, Jalkanen Henna P, de Mello Vanessa DF, Laaksonen David E, Lindi Virpi I, Ågren Jyrki J, Lakka Timo A. 2016. American journal of clinical nutrition. 104: 964-972 A1 Journal article (refereed), original research -
Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index
Hinney A, Kesselmeier M, Jall S, Volckmar AL, Föcker M, Antel J, Heid IM, Winkler TW, Grant SF, Guo Y, Bergen AW, Kaye W, Berrettini W, Hakonarson H, Herpertz-Dahlmann B, de Zwaan M, Herzog W, Ehrlich S, Zipfel S, Egberts KM et al., GCAN, WTCCC3, EGG, GIANT, Price Foundation Collaborative Group, Children's Hospital of Philadelphia/Price Foundation. 2016. Molecular psychiatry. 2017; 22: 192-201 A1 Journal article (refereed), original research -
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Physical activity and sedentary time in relation to academicachievement in children
Haapala EA, Väistö J, Lintu N, Westgate K, Ekelund U, Poikkeus A-M, Brage S, Lakka TA. 2016. Journal of science and medicine in sport. 2017; 20: 583-589 A1 Journal article (refereed), original research -
Plasma polyunsaturated fatty acids are directly associated with cognition in overweight children but not in normal weight children
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Prevalence and associated factors of abnormal liver values in children with celiac disease
Aarela Linnea, Nurminen Samuli, Kivela Laura, Huhtala Heini, Maki Markku, Viitasalo Anna, Kaukinen Katri, Lakka Timo, Kurppa Kalle. 2016. Digestive and liver disease. 48: 1023-1029 A1 Journal article (refereed), original research -
Response: food fortification as a means to increase vitamin D intake
Soininen Sonja, Eloranta Aino-Maija, Lindi Virpi, Lakka Timo A. 2016. British journal of nutrition. 116: 1134-1135 A1 Journal article (refereed), original research -
The Effects of a 2-year Individualized and Family-based Lifestyle Intervention on Physical Activity, Sedentary Behavior and Diet in Children
Viitasalo Anna, Eloranta Aino-Maija, Lintu Niina, Väistö Juuso, Venäläinen Taisa, Kiiskinen Sanna, Karjalainen Panu, Peltola Jaana, Lampinen Eeva-Kaarina, Haapala Eero A, Paananen Jussi, Schwab Ursula, Lindi Virpi, Lakka Timo A. 2016. Preventive medicine. 87: 81-88 A1 Journal article (refereed), original research -
The genetic regulatory signature of type 2 diabetes in human skeletal muscle
Scott Laura J, Erdos Michael R, Huyghe Jeroen R, Welch Ryan P, Beck Andrew T, Wolford Brooke N, Chines Peter S, Didion John P, Narisu Narisu, Stringham Heather N, Taylor D Leeland, Jackson Anne U, Vadlamudi Swarooparani, Bonnycastle Bonny M, Kinnunen Leena, Saramies Jouko, Sundvall Jouko, D'Oliveira Albanus Ricardo, Kiseleva Anna, Hensley John et al (inc. LakkaTimo A, Laakso Markku). 2016. Nature communications. 7: 11764 A1 Journal article (refereed), original research -
The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals
Ehret GB, Ferreira T, Chasman DI, Jackson AU, Schmidt EM, Johnson T, Thorleifsson G, Luan J, Donnelly LA, Kanoni S, Petersen AK, Pihur V, Strawbridge RJ, Shungin D, Hughes MF, Meirelles O, Kaakinen M, Bouatia-Naji N, Kristiansson K, Shah S et al.. 2016. Nature genetics. 48: 1171-1184 A1 Journal article (refereed), original research -
Tieteelliset perusteet varhaisvuosien fyysisen aktiivisuuden suosituksille
Sääkslahti Arja, Muuronen Kaisu, Haapala Eero, Pulakka Anna, Haapala Henna, Lakka Timo A, Laukkanen Arto, Määttä Suvi, Reunamo Jyrki, Roos Eva, Soini Anne, Mäki Päivi, Iivonen Susanna, Asunta Piritta, Viholainen Helena, Ahonen Timo, Rintala Pauli, Cantell Marja, Kyhälä Anna-Liisa. 2016. Opetus- ja kulttuuriministeriön julkaisuja. . D4 Published development or research report or study -
Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension
Surendran P, Drenos F, Young R, Warren H, Cook JP, Manning AK, Grarup N, Sim X, Barnes DR, Witkowska K, Staley JR, Tragante V, Tukiainen T, Yaghootkar H, Masca N, Freitag DF, Ferreira T, Giannakopoulou O, Tinker A, Harakalova M et al. 2016. Nature genetics. 48: 1151-1161 A1 Journal article (refereed), original research -
Association of plasma fatty acid composition with plasma irisin levels in normal weight and overweight/obese children
Viitasalo A, Ågren J, Venäläinen T, Pihlajamäki J, Jääskeläinen J, Korkmaz A, Atalay M, Lakka TA. 2015. Pediatric obesity. 2015; 11: 299-305 A1 Journal article (refereed), original research -
Associations of Physical Performance and Adiposity with Cognition in Children
Haapala Eero A, Lintu Niina, Väistö Juuso, Robinson Leah E, Viitasalo Anna, Lindi Virpi, Lakka Timo A. 2015. Medicine and science in sports and exercise. 47: 2166-2174 A1 Journal article (refereed), original research -
Associations of cardiorespiratory fitness, physical activity, and adiposity with arterial stiffness in children
Veijalainen A, Tompuri T, Haapala EA, Viitasalo , Lintu N, Väistö J, Laitinen T, Lindi V, Lakka TA. 2015. Scandinavian journal of medicine and science in sports. [epub ahead of print 29 Jul 2015]: - A1 Journal article (refereed), original research -
Associations of diet quality with cognition in children - the Physical Activity and Nutrition in Children Study
Haapala Eero A, Eloranta Aino-Maija, Venäläinen Taiisa, Schwab Ursula, Lindi Virpi, Lakka Timo A. 2015. British journal of nutrition. 114: 1080-1087 A1 Journal article (refereed), original research -
Biological interpretation of genome-wide association studies using predicted gene functions
Pers Tune H, Karjalainen Juha M, Chan Yingleong, Westra Harm-Jan, Wood Andrew R, Yang Jian, Lui Julian C, Vedantam Sailaja, Gustafsson Stefan, Esko Tonu, Frayling Tim, Speliotes Elizabeth K, Genetic Investigation of ANthropometric Traits (GIANT) Consortium (incl. Johanna Kuusisto, Markku Laakso, Timo Lakka, Matti Uusitupa), Boehnke Michael, Raychaudhuri Soumya, Fehrmann Rudolf SN, Hirschhorn Joel N, Franke Lude. 2015. Nature communications. 6: 5890 A1 Journal article (refereed), original research -
Cardiopulmonary fitness is a function of lean mass, not total body weight: The DR's EXTRA study
Krachler Benno, Savonen Kai, Komulainen Pirjo, Hassinen Maija, Lakka Timo A., Rauramaa Rainer. 2015. European journal of preventive cardiology. 22: 1171-1179 A1 Journal article (refereed), original research -
Cross-sectional associations of plasma fatty acid composition and estimated desaturase and elongase activities with cardiometabolic risk in Finnish children - The PANIC study
Venäläinen Taisa, Ågren Jyrki, Schwab Ursula, de Mello Vanessa D, Eloranta Aino-Maija, Laaksonen David E, Lindi Virpi, Lakka Timo A. 2015. Journal of clinical lipidology. 2016; 10: 82-91 A1 Journal article (refereed), original research -
Dietary Intake, FTO Genetic Variants, and Adiposity: A Combined Analysis of Over 16,000 Children and Adolescents
Qi Qibin, Downer Mary K, Kilpeläinen Tuomas O, Taal H Rob, Barton Sheila J, Ntalla Ioanna, Standl Marie, Boraska Vesna, Huikari Ville, Kiefte-de Jong Jessica C, Körner Antje, Lakka Timo A, Liu Gaifen, Magnusson Jessica, Okuda Masayuki, Raitakari Olli, Richmond Rebecca, Scott Robert A, Bailey Mark ES, Scheuermann Kathrin et al. 2015. Diabetes. 64: 2467-2476 A1 Journal article (refereed), original research -
Finger skin temperatures in 8- to 11-year-old children: determinants including physical characteristics and seasonal variation. The Physical Activity an Nutrition in Children (PANIC) Study
Zaproudina Nina, Närhi Matti, Veijalainen Aapo, Laitinen Tomi, Lakka Timo A. 2015. European journal of applied physiology. [epub ahead of print 26 Nov 2015]: 1-9 A1 Journal article (refereed), original research -
Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci
Gaulton KJ, Ferreira T, Lee Y, Raimondo A, Mägi R, Reschen ME, Mahajan A, Locke A, William Rayner N, Robertson N, Scott RA, Prokopenko I, Scott LJ, Green T, Sparso T, Thuillier D, Yengo L, Grallert H, Wahl S, Frånberg M et al.. 2015. Nature genetics. 47: 1415-1425 A1 Journal article (refereed), original research -
Genetic studies of body mass index yield new insights for obesity biology
Locke Adam E, Kahali Bratati, Berndt Sonja I, Justice Anne E, Pers Tune H, Day Felix R, Powell Corey, Vedantam Sailaja, Buchkovich Martin L, Yang Jian, Croteau-Chonka Damien C, Esko Tonu, Fall Tove, Ferreira Teresa, Gustafsson Stefan, Kutalik Zoltán, Luan Jian'an, Mägi Reedik, Randall Joshua C, Winkler Thomas W et al. 2015. Nature. 518: 197-206 A1 Journal article (refereed), original research -
Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index
Felix Janine F, Bradfield Jonathan P, Monnereau Claire, van der Valk Ralf JP, Stergiakouli Evie, Chesi Alessandra, Gaillard Romy, Feenstra Bjarke, Thiering Elisabeth, Kreiner-Møller Eskil, Mahajan Anubha, Pitkänen Niina, Joro Raimo, Cavadino Alana, Huikari Ville, Franks Steve, Groen-Blokhuis Maria M, Cousminer Diana L, Marsh Julie A, Lehtimäki Terho et al.; Early Growth Genetics (EGG) Consortium; Bone Mineral Density in Childhood Study BMDCS Consortium. 2015. Human molecular genetics. (2016) 25: 389-403 A1 Journal article (refereed), original research -
Lateral facial profile may reveal the risk for sleep disordered breathing in children - The PANIC-study
Ikävalko Tiina, Närhi Matti, Lakka Timo, Myllykangas Riitta, Tuomilehto Henri, Vierola Anu, Pahkala Riitta. 2015. Acta odontologica scandinavica. online April 20, 2015: 6 p A1 Journal article (refereed), original research -
Motor cortical alterations in children with Asperger's syndrome studied with navigated TMS
Säisänen Laura, Könönen Mervi, Anttonen Meri, Niskanen Eini, Lintu Niina, Lindi Virpi, Lakka Timo, Vanninen Ritva, Makkonen Ismo, Julkunen Petro, Määttä Sara. 2015. -
New genetic loci link adipose and insulin biology to body fat distribution
Shungin Dmitry, Winkler Thomas W, Croteau-Chonka Damien C, Ferreira Teresa, Locke Adam E, Mägi Reedik, Strawbridge Rona J, Pers Tune H, Fischer Krista, Justice Anne E, Workalemahu Tsegaselassie, Wu Joseph MW, Buchkovich Martin L, Heard-Costa Nancy L, Roman Tamara S, Drong Alexander W, Song Ci, Gustafsson Stefan, Day Felix R, Esko Tonu et al. 2015. Nature. 518: 187-196 A1 Journal article (refereed), original research -
Obesity is an important source of bias in the assessment of cardiorespiratory fitness
Krachler Benno, Savonen Kai, Lakka Timo. 2015. American heart journal. 170: e7-e8 A1 Journal article (refereed), original research -
Secular trends affect timing of emergence of permanent teeth
Eskeli Ritva, Lösönen Matias, Ikävalko Tiina, Myllykangas Riitta, Lakka Timo, Laine-Alava Maija T. 2015. Angle orthodontist. Published Online: April 29, 2015: 6 p A1 Journal article (refereed), original research -
The 148 M allele of the PNPLA3 is associated with plasma irisin levels in a population sample of Caucasian children: The PANIC Study
Viitasalo Anna, Mustafa Atalay, Pihlajamäki Jussi, Jääskeläinen Jarmo, Korkmaz Ayhan, Kaminska Dorota, Lindi Virpi, Lakka Timo A.. 2015. Metabolism: clinical and experimental. 64: 793-796 A1 Journal article (refereed), original research -
The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study
Winkler Thomas W, Justice Anne E, Graff Mariaelisa, Barata Llilda, Feitosa Mary F, Chu Su, Czajkowski Jacek, Esko Tõnu, Fall Tove, Kilpeläinen Tuomas O, Lu Yingchang, Mägi Reedik, Mihailov Evelin, Pers Tune H, Rüeger Sina, Teumer Alexander, Ehret Georg B, Ferreira Teresa, Heard-Costa Nancy L, Karjalainen Juha et al. 2015. PLoS genetics. 11: e1005378 A1 Journal article (refereed), original research -
The value of cardiorespiratory fitness and exercise-induced ST segment depression in predicting death from coronary heart disease
Hagnas Magnus J., Kurl Sudhir, Rauramaa Rainer, Lakka Timo A., Makikallio Timo H., Savonen Kai, Laukkanen Jari A.. 2015. International journal of cardiology. 196: 31-33 B1 Non-refereed journal articles -
VO2max/kg is expected to be lower in obese individuals!
Krachler Benno, Savonen Kai, Komulainen Pirjo, Hassinen Maija, Lakka Timo A, Rauramaa Rainer. 2015. International journal of cardiology. 189: 234 A1 Journal article (refereed), original research -
A Central Role for GRB10 in Regulation of Islet Function in Man
Prokopenko Inga, Poon Wenny, Mägi Reedik, Prasad BR, Salehi S Albert, Almgren Peter, Osmark Peter, Bouatia-Naji Nabila, Wierup Nils, Fall Tove, Stancáková Alena, Barker Adam, Lagou Vasiliki, Osmond Clive, Xie Weijia, Lahti Jari, Jackson Anne U, Cheng Yu-Ching, Liu Jie, O'Connell Jeffrey R et al. (including Kuusisto Johanna, Laakso Markku, Lakka Timo). 2014. PLoS genetics. 10: e1004235 A1 Journal article (refereed), original research -
A novel common variant in DCST2 is associated with length in early life and height in adulthood
van der Valk Ralf JP, Kreiner-Moller Eskil, Kooijman Marjolein N, Guxens Mònica, Stergiakouli Evangelia, Sääf Annika, Bradfield Jonatan P, Geller Frank, Geoffrey Hayes M, Cousminer Diana L, Körner Antje, Thiering Elisabeth, Curtin John A, Myhre Ronny, Huikari Ville, Joro Raimo, Kerkhof Marjan, Warrington Nicole M, Pitkänen Niina, Ntalla Ioanna et. al.. 2014. Human molecular genetics. Epub ahead of print: - A1 Journal article (refereed), original research -
Associations Of Cardiovascular Fitness, Motor Performance And Adiposity With Cognition In Children
Haapala Eero A, Tompuri Tuomo, Lintu Niina, Laitinen Tomi, Lindi Virpi, Lakka Timo A. 2014. MEDICINE AND SCIENCE IN SPORTS AND EXERCISE. SUPPLEMENT -
Associations of I148M variant in PNPLA3 gene with plasma ALT levels during 2-year follow-up in normal weight and overweight children: the PANIC Study
Viitasalo A, Pihlajamaki J, Lindi V, Atalay M, Kaminska D, Joro R, Lakka TA. 2014. Pediatric obesity. -: A1 Journal article (refereed), original research -
Cardiorespiratory fitness, respiratory function and hemodynamic responses to maximal cycle ergometer exercise test in girls and boys aged 9-11 years: the PANIC Study
Lintu Niina, Viitasalo Anna, Tompuri Tuomo, Veijalainen Aapo, Hakulinen Mikko, Laitinen Tomi, Savonen Kai, Lakka Timo A. 2014. European journal of applied physiology. Epub ahead of print: - A1 Journal article (refereed), original research -
Correlates of Low Physical Activity Levels in Aging Men and Women: The DR's EXTRA Study
Hakola Leena, Hassinen Maija, Komulainen Pirjo, Lakka Timo A, Savonen Kai, Rauramaa Rainer. 2014. Journal of aging and physical activity. Epub ahead of print: - A1 Journal article (refereed), original research -
Cross-Sectional Associations of Food Consumption with Plasma Fatty Acid Composition and Estimated Desaturase Activities in Finnish Children
Venäläinen Taisa, Schwab Ursula, Ågren Jyrki, de Mello Vanessa, Lindi Virpi, Eloranta Aino-Maija, Kiiskinen Sanna, Laaksonen David, Lakka Timo A. 2014. Lipids. 49: 467-479 A1 Journal article (refereed), original research -
Defining the role of common variation in the genomic and biological architecture of adult human height
Wood Andrew R, Esko Tonu, Yang Jian, Vedantam Sailaja, Pers Tune H, Gustafsson Stefan, Chu Audrey Y, Estrada Karol, Luan Jian'an, Kutalik Zoltán, Amin Najaf, Buchkovich Martin L, Croteau-Chonka Damien C, Day Felix R, Duan Yanan, Fall Tove, Fehrmann Rudolf, Ferreira Teresa, Jackson Anne U, Karjalainen Juha et.al.. 2014. Nature genetics. 46: 1173-86 A1 Journal article (refereed), original research -
Effects of extended-release niacin with laropiprant in high-risk patients
HPS2-THRIVE Collaborative Group, Landray MJ, Haynes R, Hopewell JC, Parish S, Aung T, Tomson J, Wallendszus K, Craig M, Jiang L, Collins R, Armitage J. 2014. The new england journal of medicine. 371: 203-212 A1 Journal article (refereed), original research -
Ennenaikaisen adrenarken sukupuolierot saattavat johtua erilaisesta kehon rasvakoostumuksesta
Mäntyselkä Aino, Jääskeläinen Jarmo, Lindi Virpi, Viitasalo Anna, Tompuri Tuomo, Voutilainen Raimo, Lakka Timo A. 2014. Duodecim. 130: 101 D1 Article in a trade journal -
Genome-wide Enrichment Analysis between Endometriosis and Obesity-related Traits Reveals Novel Susceptibility Loci
Rahmioglu Nilufer, Macgregor Stuart, Drong Alexander W, Hedman Åsa K, Harris Holly R, Randall Joshua C, Prokopenko Inga, The International EndoGene Consortium (IEC), The GIANT Consortium, Nyholt Dale R, Morris Andrew P, Montgomery Grant W, Missmer Stacey A, Lindgren Cecilia M, Zondervan Krina T. 2014. Human molecular genetics. Epub ahead of print: - A1 Journal article (refereed), original research -
Genome-wide association study of sexual maturation in males and females highlights a role for body mass and menarche loci in male puberty
Cousminer Diana L, Stergiakouli Evangelia, Berry Diane J, Ang Wei, Groen-Blokhuis Maria M, Körner Antje, Siitonen Niina, Ntalla Ioanna, Marinelli Marcella, Perry John RB, Kettunen Johannes, Jansen Rick, Surakka Ida, Timpson Nicholas J, Ring Susan, Mcmahon George, Power Chris, Wang Carol, Kähönen Mika, Jorma Viikari et. al.. 2014. Human molecular genetics. 23: 4451-64 A1 Journal article (refereed), original research -
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
Diabetes Genetics Replication and Meta-analysis (DIAGRAM) Consortium, Asian Genetic Epidemiology Network Type 2 Diabetes (AGEN-T2D) Consortium, South Asian Type 2 Diabetes (SAT2D) Consortium, Mexican American Type 2 Diabetes (MAT2D) Consortium, Type 2 Diabetes Genetic Exploration by Nex-generation sequencing in multi-Ethnic Samples (T2D-GENES) Consortium, Mahajan A, Go MJ, Zhang W, Below JE, Gaulton KJ, Ferreira T, Horikoshi M, Johnson AD, Ng MC, Prokopenko I, Saleheen D, Wang X, Zeggini E, Abec. 2014. Nature genetics. 46: 234-244 A1 Journal article (refereed), original research -
Measures of cardiorespiratory fitness in relation to measures of body size and composition among children
Tompuri Tuomo, Lintu Niina, Savonen Kai, Laitinen Tomi, Laaksonen David, Jääskeläinen Jarmo, Lakka Timo A. 2014. Clinical physiology and functional imaging. Epub ahead of print: - A1 Journal article (refereed), original research -
Moderators of Maintained Increase in Aerobic Exercise Among Aging Men and Women in a 4-year Randomized Controlled Trial: The DR's EXTRA Study
Hakola Leena, Savonen Kai, Komulainen Pirjo, Hassinen Maija, Rauramaa Rainer, Lakka Timo A. 2014. Journal of physical activity and health. -: - A1 Journal article (refereed), original research -
Novel approach identifies SNPs in SLC2A10 and KCNK9 with evidence for parent-of-origin effect on body mass index
Hoggart Clive J, Venturini Giulia, Mangino Massimo, Gomez Felicia, Ascari Giulia, Zhao Jing Hua, Teumer Alexander, Winkler Thomas W, T¨ernikova Natalia, Luan Jian'an, Mihailov Evelin, Ehret Georg B, Zhang Weihua, Lamparter David, Esko Tõnu, Macé Aurelian, Rüeger Sina, Bochud Pierre-Yves, Barcella Matteo, Dauvilliers Yves et al (including Atalay Mustafa, Kuusisto Johanna, Lakka Timo, Yaluri Alena, Laakso Markku, Uusitupa Matti). 2014. PLoS genetics. 10: e1004508 A1 Journal article (refereed), original research -
Physical activity and sedentary behaviour in relation to cardiometabolic risk in children: cross-sectional findings from the Physical Activity and Nutrition in Children (PANIC) Study
Väistö J, Eloranta A-M, Viitasalo A, Tompuri T, Lintu N, Karjalainen P, Lampinen E-K, Ågren J, Laaksonen DE, Lakka H-M, Lindi V, Lakka TA. 2014. International journal of behavioral nutrition and physical activity. 11: 55 A1 Journal article (refereed), original research -
The presentation of adrenarche is sexually dimorphic and modified by body adiposity
Mäntyselkä Aino, Jääskeläinen Jarmo, Lindi Virpi, Viitasalo Anna, Tompuri Tuomo, Voutilainen Raimo, Lakka Timo A. 2014. Journal of clinical endocrinology and metabolism. 99: 3889-3894 A1 Journal article (refereed), original research -
Validation of metabolic syndrome score by confirmatory factor analysis in children and adults and prediction of cardiometabolic outcomes in adults
Viitasalo Anna, Lakka Timo A, Laaksonen David E, Savonen Kai, Lakka Hanna-Maaria, Hassinen Maija, Komulainen Pirjo, Tompuri Tuomo, Kurl Sudhir, Laukkanen Jari A, Rauramaa Rainer. 2014. Diabetologia. Epub ahead of print: - A1 Journal article (refereed), original research -
Assessment of body composition by dual-energy X-ray absorptiometry, bioimpedance analysis and anthropometrics in children: the Physical Activity and Nutrition in Children study
Tompuri TT, Lakka TA, Hakulinen M, Lindi V, Laaksonen DE, Kilpeläinen TO, Jääskeläinen J, Lakka H-M, Laitinen T. 2013. Clinical physiology and functional imaging. 2015; 35: 21-33 A1 Journal article (refereed), original research -
Associations of motor and cardiovascular performance with academic skills in children
Haapala EA, Poikkeus A-M, Tompuri T, Kukkonen-Harjula K, Leppänen PHT, Lindi V, Lakka TA. 2013. Medicine and science in sports and exercise. online: x-x A1 Journal article (refereed), original research -
Cardiovascular fitness and haemodynamic responses to maximal cycle ergometer exercise test in children 6-8 years of age
Lintu N, Tompuri T, Viitasalo A, Soininen S, Laitinen T, Savonen K, Lindi V, Lakka TA. 2013. Journal of sports sciences. online: - A1 Journal article (refereed), original research -
Common variants associated with plasma triglycerides and risk for coronary artery disease
Do R, Willer CJ, Schmidt EM, Sengupta S, Gao C, Peloso GM, Gustafsson S, Kanoni S, Ganna A, Chen J, Buchkovich ML, Mora S, Beckmann JS, Bragg-Gresham JL, Chang H-Y, Demirkan A, Den Hertog HM, Donnelly LA, Ehret GB, Esko T et.al.. 2013. Nature genetics. 45: 1345-52 A1 Journal article (refereed), original research -
Dietary factors associated with metabolic risk score in Finnish children aged 6-8 years: the PANIC study
Eloranta AM, Lindi V, Schwab U, Kiiskinen S, Venäläinen T, Lakka HM, Laaksonen DE, Lakka TA. 2013. European journal of nutrition. online: - A1 Journal article (refereed), original research -
Discovery and refinement of loci associated with lipid levels
Willer CJ, Schmidt EM, Sengupta S, Peloso GM, Gustafsson S, Kanoni S, Ganna A, Chen J, Buchkovich ML, Mora S, Beckmann JS, Bragg-Gresham JL, Chang H-Y, Demirkan A, Den Hertog HM, Do R, Donnelly LA, Ehret GB, Esko T, Feitosa MF et.al.. 2013. Nature genetics. 45: 1274-1283 A1 Journal article (refereed), original research -
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture
Berndt SI, Gustafsson S, Mägi R, Ganna A, Wheeler E, Feitosa MF, Justice AE, Monda KL, Croteau-Chonka DC, Day FR, Esko T, Fall T, Ferreira T, Gentilini D, Jackson AU, Luan J, Randall JC, Vedantam S, Willer CJ, Winkler TW, et al. (including Atalay M, Kuusisto J, Lakka TA, Stancakova A, Laakso M, Uusitupa M). 2013. Nature genetics. 45: 501-512 A1 Journal article (refereed), original research -
Lapsuusiän liikunnan merkitys - kardiometabolinen näkökulma
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Meta-analysis of gene-level associations for rare variants based on single-variant statistics
Hu Y-J, Berndt SI, Gustafsson S, Ganna A, Genetic Investigation of ANthropometric Traits (GIANT) Consortium (including M Atalay, T Lakka, J Kuusisto, M Laakso), Hirschhorn J, North KE, Ingelsson E, Lin D-Y et.al.. 2013. American journal of human genetics. 93: 236-248 A1 Journal article (refereed), original research -
Metabolic risk factors are associated with stiffness index, reflection index and finger skin temperature in children
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Normal values for heart rate variability parameters in children 6-8 years of age: the PANIC Study
Seppälä S, Laitinen T, Tarvainen MP, Tompuri T, Veijalainen A, Savonen K, Lakka T. 2013. Clinical physiology and functional imaging. Article first published online: - A1 Journal article (refereed), original research -
Sex-stratified Genome-wide Association Studies Including 270,000 Individuals Show Sexual Dimorphism in Genetic Loci for Anthropometric Traits
Randall JC, Winkler TW, Kutalik Z, Berndt SI, Jackson AU, Monda KL, Kilpeläinen TO, Esko T, Mägi R, Li S, Workalemahu T, Feitosa MF, Croteau-Chonka DC, Day FR, Fall T, Ferreira T, Gustafsson S, Locke AE, Mathieson I, Scherag A, et al. (including J Kuusisto, M Laakso, M Atalay, T Lakka). 2013. PLoS genetics. 9: e1003500 A1 Journal article (refereed), original research -
Trans-Ethnic Fine-Mapping of Lipid Loci Identifies Population-Specific Signals and Allelic Heterogeneity That Increases the Trait Variance Explained
Wu Y, Waite LL, Jackson AU, Sheu WH, Buyske S, Absher D, Arnett DK, Boerwinkle E, Bonnycastle LL, Carty CL, Cheng I, Cochran B, Croteau-Chonka DC, Dumitrescu L, Eaton CB, Franceschini N, Guo X, Henderson BE, Hindorff LA, Kim E, et al. (including Stancakova A, Kuusisto J, Laakso M, Uusitupa M, Rauramaa R Lakka T.). 2013. PLoS genetics. 9: e1003379 A1 Journal article (refereed), original research -
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance
Manning AK, Hivert MF, Scott RA, Grimsby JL, Bouatia-Naji N, Chen H, Rybin D, Liu CT, Bielak LF, Prokopenko I, Amin N, Barnes D, Cadby G, Hottenga JJ, Ingelsson E, Jackson AU, Johnson T, Kanoni S, Ladenvall C, Lagou V et.al.. 2012. Nature genetics. 44: 659-669 A1 Journal article (refereed), original research -
A genome-wide association meta-analysis identifies new childhood obesity loci
Bradfield JP, Taal HR, Timpson NJ, Scherag A, Lecoeur C, Warrington NM, Hypponen E, Holst C, Valcarcel B, Thiering E, Salem RM, Schumacher FR, Cousminer DL, Sleiman PMA, Zhao J, Berkowitz RI, Vimaleswaran KS, Jarick I, Pennell CE, Evans DM et.al.. 2012. Nature genetics. 44: 526-531 A1 Journal article (refereed), original research -
Clinical signs of temporomandibular disorders and various pain conditions among children 6 to 8 years of age: The Panic Study
Vierola A, Suominen AL, Ikävalko T, Lintu N, Lindi V, Lakka H-M, Kellokoski J, Närhi M, Lakka TA. 2012. Journal of orofacial pain. 26: 17-25 A1 Journal article (refereed), original research -
Clustering of Metabolic Risk Factors Is Associated with High-Normal Levels of Liver Enzymes among 6- to 8-Year-Old Children: The PANIC Study
Viitasalo A, Laaksonen DE, Lindi V, Eloranta A-M, Jääskeläinen J, Tompuri T, Väisänen S, Lakka H-M, Lakka TA. 2012. Metabolic syndrome and related disorders. 10: 337-343 A1 Journal article (refereed), original research -
Common variants at 12q15 and 12q24 are associated with infant head circumference
Taal HR, St Pourcain B, Thiering E, Das S, Mook-Kanamori DO, Warrington NM, Kaakinen M, Kreiner-Moller E, Bradfield JP, Freathy RM, Geller F, Guxens M, Cousminer DL, Kerkhof M, Timpson NJ, Ikram MA, Beilin LJ, Bonnelykke K, Buxton JL, Charoen P et.al.. 2012. Nature genetics. 44: 532-538 A1 Journal article (refereed), original research -
Common variants at 6q22 and 17q21 are associated with intracranial volume
Ikram MA, Fornage M, Smith AV, Seshadri S, Schmidt R, Debette S, Vrooman HA, Sigurdsson S, Ropele S, Taal HR, Kanamori-Mook DO, Coker LH, Longstreth Jr WT, Niessen WJ, DeStefano AL, Beiser A, Zijdenbos AP, Struchalin M, Jack Jr CR, Rivadeneira F et.al.. 2012. Nature genetics. 44: 539-544 A1 Journal article (refereed), original research -
Craniofacial morphology but not excess body fat is associated with risk of having sleep-disordered breathing -The PANIC Study (a questionnaire-based inquiry in 6-8-year-olds)
Ikävalko T, Tuomilehto H, Pahkala R, Tompuri T, Laitinen T, Myllykangas R, Vierola A, Lindi V, Närhi M, Lakka TA. 2012. European journal of pediatrics. 171: 1747-1752 A1 Journal article (refereed), original research -
Determinants of pain and functioning in hip osteoarthritis - a two-year prospective study
Juhakoski R, Malmivaara A, Lakka TA, Tenhonen S, Hannila M-L, Arokoski JPA. 2012. Clinical rehabilitation. online: - A1 Journal article (refereed), original research -
Diet, fitness and metabolic syndrome - The DR's EXTRA Study
Kouki R, Schwab U, Lakka TA, Hassinen M, Savonen K, Komulainen P, Krachler B, Rauramaa R. 2012. Nutrition metabolism and cardiovascular diseases. 22: 553-560 A1 Journal article (refereed), original research -
Dietary factors associated with overweight and body adiposity in Finnish children aged 6-8 years: the PANIC study
Eloranta A-M, Lindi V, Schwab U, Tompuri T, Kiiskinen S, Lakka H-M, Laitinen T, Lakka TA. 2012. International journal of obesity. 36: 950-955 A1 Journal article (refereed), original research -
Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways
Scott RA, Lagou V, Welch RP, Wheeler E, Montasser ME, Luan J, Mägi R, Strawbridge RJ, Rehnberg E, Gustafsson S, Kanoni S, Rasmussen-Torvik L, Yengo L, Lecoeur C, Shungin D, Sanna S, Sidore C, Johnson PCD, Jukema JW, Johnson T et.al.. 2012. Nature genetics. 44: 991-1005 A1 Journal article (refereed), original research -
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes
Morris AP, Voight BF, Teslovich TM, Ferreira T, Segrè AV, Steinthorsdottir V, Strawbridge RJ, Khan H, Grallert H, Mahajan A, Prokopenko I, Kang HM, Dina C, Esko T, Fraser RM, Kanoni S, Kumar A, Lagou V, Langenberg C, Luan J et.al.. 2012. Nature genetics. 44: 981-990 A1 Journal article (refereed), original research -
Low-grade inflammation and depressive symptoms as predictors of abdominal obesity
Valtonen MK, Laaksonen DE, Laukkanen JA, Tolmunen T, Viinamäki H, Lakka H-M, Lakka TA, Niskanen L, Kauhanen J. 2012. Scandinavian journal of public health. 40: 674-680 A1 Journal article (refereed), original research -
New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism
Horikoshi M, Yaghootkar H, Mook-Kanamori DO, Sovio U, Taal HR, Hennig BJ, Bradfield JP, St Pourcain B, Evans DM, Charoen P, Kaakinen M, Cousminer DL, Lehtimäki T, Kreiner-Møller E, Warrington NM, Bustamante M, Feenstra B, Berry DJ, Thiering E et.al.. 2012. Nature genetics. -: 1-10 A1 Journal article (refereed), original research -
Purchase of antidepressant agents by patients with type 1 diabetes is associated with increased mortality rates in women but not in men
Ahola AJ, Harjutsalo V, Saraheimo M, Forsblom C, Groop PH; FinnDiane Study Group.. 2012. Diabetologia. 55: 73-79 A1 Journal article (refereed), original research -
Two-minute heart rate recovery after cycle ergometer exercise and all-cause mortality in middle-aged men
Savonen KP, Kiviniemi V, Laaksonen DE, Lakka TA, Laukkanen JA, Tuomainen T-P, Rauramaa R. 2012. Journal of internal medicine. 270: 589-596 A1 Journal article (refereed), original research -
Cardiorespiratory fitness in aging men and women: the DR's EXTRA study
Hakola L, Komulainen P, Hassinen M, Savonen K, Litmanen H, Lakka TA, Rauramaa R. 2011. Scandinavian journal of medicine and science in sports. 21: 679-687 A1 Journal article (refereed), original research -
Dietary factors and their associations with socioeconomic background in Finnish girls and boys 6-8 years of age: the PANIC Study
Eloranta AM, Lindi V, Schwab U, Kiiskinen S, Kalinkin M, Lakka HM, Lakka TA. 2011. European journal of clinical nutrition. 65: 1211-8 A1 Journal article (refereed), original research -
Fine mapping of five loci associated with low-density lipoprotein cholesterol detects variants that double the explained heritability
Sanna S, Li B, Mulas A, Sidore C, Kang HM, Jackson AU, Grazia Piras M, Usala G, Maninchedda G, Sassu A, Serra F, Palmas MA, Wood III WH, Njølstad I, Laakso M, Hveem K, Tuomilehto J, Lakka TA, Rauramaa R, Boehnke M,et al.. 2011. PLoS genetics. 7: e1002198 A1 Journal article (refereed), original research -
Food consumption, nutrient intake and the risk of having metabolic syndrome: the DR's EXTRA Study.
Kouki R, Schwab U, Hassinen M, Komulainen P, Heikkilä H, Lakka TA, Rauramaa R.. 2011. European journal of clinical nutrition. 65: 368-377 A1 Journal article (refereed), original research -
Liikunta. Käypä hoito -suositus
Kesäniemi A , Kettunen J, Ketola E, Kujala U, Kukkonen-Harjula K, Lakka T, Rauramaa R, Rauramo I, Tikkanen H, Vuori I. 2011. Duodecim. 127: 150-151 A1 Journal article (refereed), original research -
Physical activity attenuates the influence of FTO variants on obesity risk: A meta-analysis of 218,166 adults and 19,268 children
Kilpeläinen Tuomas O, Qi Lu, Brage Soren, Sharp Stephen J., Sonestedt Emily, Demerath Ellen, Ahmad Tariq, Mora Samia, Kaakinen Marika, Sandholt Camilla H, Holzapfel Christina, Autenrieth Christine S., Hyppönen Elina, Cauchi Stéphane , He Meian, Kutalik Zoltan, Kumari Meena, Stancaková Alena, Meidtner Karina, Balkau Beverley et al.. 2011. PLoS medicine. 8: e1001116 A1 Journal article (refereed), original research -
Physical activity, body composition and sleep in children
Lintu N, Himanen A, Karjalainen P, Elonranta A-M, Tompuri T, Viitasalo A, Laitinen T, Tuomilehto H, Lakka H-M, Lindi V, Lakka T. Teoksessa: Hakkarainen Anni, Liukkonen Jarmo, Linnamo Vesa(toim.) , 2011. International congress on enhancement of physical activity of children and youth 2011. s. 45. Jyväskylän yliopisto A4 Conference proceedings -
Reproducibility of pulse contour analysis in children before and after maximal exercise stress test: The physical activity and nutrition in children (PANIC) study
Veijalainen A, Tompuri T, Lakka H-M, Laitinen T, & Lakka TA. 2011. Clinical physiology and functional imaging. 31: 132-138 A1 Journal article (refereed), original research -
The current standard measure of cardiorespiratory fitness introduces confounding by body mass: the DR's EXTRA study
Savonen K, Krachler B, Hassinen M, Komulainen P, Kiviniemi V, Lakka TA and Rauramaa R. 2011. International journal of obesity. 36: 1135-1140 A1 Journal article (refereed), original research -
Aikuisten liikunta
Kesäniemi A, Kettunen J, Ketola E, Kujala U, Kukkonen-Harjula K, Lakka T, Rauramaa R, Rauramo I, Tikkanen H & Vuori I. 2010. Duodecim. 126: 150-1 A2 Review article, Literature review, Systematic review -
Cardiorespiratory fitness and metabolic syndrome in older men and women
Hassinen M, Lakka TA, Hakola L, Savonen K, Komulainen P, Litmanen H, Kiviniemi V, Kouki R, Heikkilä H, & Rauramaa R. 2010. Diabetes care. 33: 1655-1657 A1 Journal article (refereed), original research -
Cross-sectional analysis of baseline data to identify the major determinants of carotid intima-media thickness in a European population: the IMPROVE study
Baldassarre D, Nyyssönen K, Rauramaa R, de Faire U, Hamsten A, Smit AJ, Mannarino E, Humphries SE, Giral P, Grossi E, Veglia F, Paoletti R, Tremoli E; IMPROVE study group.. 2010. European heart journal. 614-22: 614-622 A1 Journal article (refereed), original research -
Exercise, fitness and cognition - A randomised controlled trial in older indivuals: The DR's EXTRA study
Komulainen P, Kivipelto M, Lakka TA, Savonen K, Hassinen M, Kiviniemi V, Hänninen T & Rauramaa R. 2010. European geriatric medicine. 1: 266-272 A1 Journal article (refereed), original research -
Lasten liikunta ja ravitsemus -tutkimus selvittää alakoululaisten elintapoja
Eloranta A-m, Lindi V, Schwab U, Kiiskinen S, Kalinkin M, Lintu N, Karjalainen P, Himanen A, Karjalainen J, Tompuri T, Viitasalo A, Lakka H-M, Lakka T & Lasten liikunta ja ravitsemus -tutkimus, Itä-Suomen yliopisto. 2010. BOLUS : RAVITSEMUSTERAPEUTTIEN YHDISTYKSEN LEHTI. : 30-33 D1 Article in a trade journal -
Leisure-time physical activity and the metabolic syndrome in the Finnish diabetes prevention study
Ilanne-Parikka P, Laaksonen DE, Eriksson JG, Lakka TA, Lindström J, Peltonen M, Aunola S, Keinänen-Kiukaanniemi S, Uusitupa M & Tuomilehto J. On behalf of the Finnish diabetes prevention study group. 2010. Diabetes care. 33: 1610-1617 A1 Journal article (refereed), original research -
Reproducibility of pulse contour analysis in children before and after maximal exercise stress test: The Physical Activity and Nutrition in Children (PANIC) Study
Veijalainen A, Tompuri T, Lakka HM, Laitinen T & Lakka TA. 2010. Clinical physiology and functional imaging. online: 1-7 A1 Journal article (refereed), original research -
Sedentary lifestyle and emergence of hopelessness in middle-aged men
Valtonen M, Laaksonen DE, Laukkanen J, Tolmunen T, Rauramaa R, Viinamäki H, Mursu J, Savonen K, Lakka TA, Niskanen L & Kauhanen J. 2010. EUROPEAN JOURNAL OF CARDIOVASCULAR PREVENTION AND REHABILITATION. 17: 524-9 A1 Journal article (refereed), original research -
Determinants of cardiorespiratory fitness in men aged 42 to 60 years with and without cardiovascular disease
Laukkanen JA, Laaksonen D, Lakka TA, Savonen K, Rauramaa R, Mäkikallio T, Kurl S. 2009. American journal of cardiology. 103: 1598-1604 A1 Journal article (refereed), original research -
Exercise and type 2 diabetes prevention
Hu G, Lakka TA, Barengo NC, Tuomilehto J. Teoksessa: Lignalli AT(toim.) , 2009. Handbook of Type 2 Diabetes in the Middle Aged and Elderly [E-Book]. s. 93-111. Nova Science Publisher A3 Book section, Chapters in research books -
Kardiorespiratorinen suorituskyky ja metabolinen oireyhtymä
Hassinen M, Savonen K, Lakka TA, Komulainen P, Litmanen H, Kiviniemi V, Kouki R, Heikkilä H, Hakola L, Rauramaa R. 2009. Liikunta ja tiede. 46: 34-35 A1 Journal article (refereed), original research -
Kardiorespiratorinen suorituskyky muistin ennustajana ikääntyneillä miehillä ja naisilla
Komulainen P, Savonen K, Litmanen H, Lakka TA, Kiviniemi V, Hassinen M, Kivipelto M, Hänninen T, Heikkilä H, Kouki R, Hakola L, Rauramaa R. 2009. Liikunta ja tiede. 46: 41 A1 Journal article (refereed), original research -
Lasten ruokavaliossa on huolestuttavia piirteitä
Kiiskinen S, Schwab U, Kalinkin M, Lindi V, Tompuri T, Lakka H-M, Lakka T. 2009. Lääkärilehti. 64: 144-145 A1 Journal article (refereed), original research -
Leisure-time physical activity, cardiorespiratory fitness and feelings of hopelessness in men
Valtonen M, Laaksonen DE, Laukkanen J, Tolmunen T, Rauramaa R, Viinamäki H, Kauhanen J, Lakka T, Niskanen L. 2009. Bmc public health. 9: A1 Journal article (refereed), original research -
Physical activity, fitness, and the preventioon of type 2 diabetes
Hu G, Lakka TA, Tuomilehto J. Teoksessa: Lee I-M(toim.) , 2009. Epidemiologic Methods in Physical Avtivity Studies. s. 201-224. Oxford University Press A3 Book section, Chapters in research books -
Association of age and education with different types of leisure-time physical activity among 4437 Finnish adults
Borodulin K, Laatikainen T, Lahti-Koski M, Jousilahti P, Lakka TA. 2008. Journal of physical activity and health. 5: 242-251 A1 Journal article (refereed), original research -
BDNF is a novel marker of cognitive function in ageing women: the DR's EXTRA Study
Komulainen P, Pedersen M, Hänninen T, Bruunsgaard H, Lakka TA, Kivipelto M, Hassinen M, Rauramaa TH, Pedersen BK, Rauramaa R. 2008. Neurobiology of learning and memory. 90: 596-603 A1 Journal article (refereed), original research -
Cardiorespiratory fitness as a feature of metabolic syndrome in older men and women
Hassinen M, Lakka TA, Savonen K, Litmanen H, Kiviaho L, Laaksonen DE, Komulainen P, Rauramaa R. 2008. Diabetes care. 31: 1242-1247 A1 Journal article (refereed), original research -
Chronotropic incompetence and mortality in middle-aged men with known or suspected coronary heart disease
Savonen KP, Kiviniemi V, Laukkanen JA, Lakka TA, Rauramaa TH, Salonen JT, Rauramaa R. 2008. European heart journal. 29: 1896-1902 A1 Journal article (refereed), original research -
Dyslipidaemia as a predictor of hypertension in middle-aged men
Laaksonen DE, Niskanen L, Nyyssönen K, Lakka TA, Laukkanen JA, Salonen JT. 2008. European heart journal. 29: 2561-2568 A1 Journal article (refereed), original research -
Interaction of single nucleotide polymorphisms in ADRB2, ADRB3, TNF, IL6, IGF1R, LIPC, LEPR, and GHRL with physical activity on the risk of type 2 diabetes mellitus and changes in characteristics of the metabolic syndrome. The Finnish Diabetes Prevention Study
Kilpeläinen TO, Lakka TA, Laakosnen DE, Mager U, Salopuro T, Kubaszek A, Todorova B, Laukkanen O, Lindström J, Eriksson JG, Hämäläinen H, Aunola S, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Tuomilehto J, Laakso M, Uusitupa M. 2008. Metabolism: clinical and experimental. 57: 428-436 A1 Journal article (refereed), original research -
Physical activity and diabetes complications in patients with type 1 diabetes. The Finnish Diabetic Nephropathy (FinnDiane) Study
Wadén J, Forsblom C, Thorn LM, Saraheimo M, Rosengård-Bärlund M, Heikkilä O, Lakka TA, Tikkanen H, Groop PH, FinnDiane Study Group, Karhapää P, Laakso M, Moilanen L, Niskanen L, Vauhkonen I, Voutilainen E. 2008. Diabetes care. 31: 230-232 A2 Review article, Literature review, Systematic review -
Physical activity, fitness, and prevention of type 2 diabetes
Hu G, Lakka TA, Tuomilehto J. Teoksessa: Lee IM(toim.) , 2008. Epidemiologic Methods in Physical Activity Studies. s. 201-224. Oxford University Press A3 Book section, Chapters in research books -
SNPs in PPARG associte with type 2 diabetes and intract with physival activity
Kilpeläinen TO, Lakka TA, Laaksonen DE, Lindström J, Eriksson JG, Valle TT, Hämäläinen H, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Lindi V, Tuomilehto J, Uusitupa M, Laakso M. 2008. Medicine and science in sports and exercise. 40: 25-33 A1 Journal article (refereed), original research -
Usefulness of chronotropic incompetence in response to exercise as a predictor of myocardial infarction in middle-aged men without cardiovascular disease
Savonen KP, Lakka TA, Laukkanen JA, Rauramaa TH, Salonen JT, Rauramaa R. 2008. American journal of cardiology. 101: 992-998 A1 Journal article (refereed), original research -
Workload at the heart rate of 100 beats/min and mortality in middle-aged men known or suspected coronary heart disease
Savonen KP, Lakka TA, Laukkanen JA, Rauramaa TH, Salonen JT, Rauramaa R. 2008. Heart. 94: E14 A1 Journal article (refereed), original research -
Association of waist and hip circumference with 12-year progression of carotid intima-media thickness in elderly women
Hassinen M, Lakka TA, Komulainen P, Haapala I, Nissinen A, Rauramaa R. 2007. International journal of obesity. 31: 1406-1411 A1 Journal article (refereed), original research -
Carotid intima-media thickness and cognitive function in elderly women: a population-based study
Komulainen P, Kivipelto M, Lakka TA, Hassinen M, Helkala E-L, Patja K, Nissinen A, Rauramaa R. 2007. Neuroepidemiology. 28: 207-213 A1 Journal article (refereed), original research -
Effectiveness of workload at the heart rate of 100 beats/min in predicting cardiovascular mortality in men aged 42, 48, 54, or 60 years at baseline
Savonen KP, Lakka TA, Laukkanen JA, Rauramaa TH, Salonen JT, Rauramaa R. 2007. American journal of cardiology. 100: 563-568 A1 Journal article (refereed), original research -
Epidemiological studies of exercise in diabetes prevention
Hu G, Lakka TA, Kilpeläinen T, Tuomilehto J. 2007. Applied physiology nutrition and metabolism-physiologie appliquee nutrition et metabolisme. 32: 583-595 A2 Review article, Literature review, Systematic review -
Leisure-time physical activity is associated with the metaboic syndrome in type 1 diabetes: Effect of the PPAR-gamma Pro12Ala polymorphism: the FinnDiane Study
Wadén J, Thorn LM, Forsblom C, Lakka T, Saraheimo M, Rosengård-Bärlund M, Heikkilä O, Wessman M, Turunen JA, Parkkonen M, Tikkanen H, Groop P-H, on behalf of the FinnDiane Study Group. 2007. Diabetes care. 30: 1618-1620 A2 Review article, Literature review, Systematic review -
Metabolic syndrome and cognitive function: a population-based follow-up study in elderly women
Komulainen P, Lakka TA, Kivipelto M, Hassinen M, Helkala E-L, Haapala I, Nissinen A, Rauramaa R. 2007. Dementia and geriatric cognitive disorders. 23: 29-34 A1 Journal article (refereed), original research -
Obesity, physical activity, and nutrition in the metabolic syndrome
Hu G, Lakka TA, Lakka H-M, Tuomilehto J, Lakka TA. Teoksessa: Krentz AJ, Wong ND(toim.) , 2007. Metabolic Syndrome and Cardiovascular Disease. s. 241-278. Informa Healthcare A3 Book section, Chapters in research books -
Occupational, commuting and leisure-time physical activity in relation to coronary heart disease among middle-aged Finnish men and women
Hu G, Jousilahti P, Borodulin K, Barengo NC, Lakka TA, Nissinen A, Tuomilehto J. 2007. Atherosclerosis. 194: 490-497 A1 Journal article (refereed), original research -
Physical activity in prevention and treatment of the metabolic syndrome
Lakka TA, Laaksonen DE. 2007. Applied physiology nutrition and metabolism-physiologie appliquee nutrition et metabolisme. 32: 76-88 A1 Journal article (refereed), original research -
Physical activity modifies the effect of SNPs in the SLC2A2 (GLUT2) and ABCC8 (SUR1) genes on the risk of developing type 2 diabetes
Kilpeläinen TO, Lakka TA, Laaksonen DE, Laukkanen O, Lindström J, Eriksson JG, Valle TT, Hämäläinen H, Aunola S, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Tuomilehto J, Uusitupa M, Laakso M, for the Finnish Diabetes Prevention Study Group, Laakso M. 2007. Physiological genomics. 31: 264-272 A1 Journal article (refereed), original research -
Serum high sensitivity C-reactive protein and cognitive function in elderly women
Komulainen P, Lakka TA, Kivipelto M, Hassinen M, Penttilä IM, Helkala E-L, Gylling H, Nissinen A, Rauramaa R. 2007. Age and ageing. 36: 443-448 A1 Journal article (refereed), original research -
Association of leisure time physical activity abdomimal obesity with fsting serum insulin and 2-h postchallenge plasma glucose levels
Borodulin K, Tuomilehto J, Peltonen M, Lakka TA, Sundvall J, Jousilahti P. 2006. Diabetic medicine. 23: 1025-1028 A1 Journal article (refereed), original research -
C-reactive protein and metabolic syndrome in elderly women. A 12-year follow-up study
Hassinen M, Lakka TA, Komulainen P, Gylling H, Nissinen A, Rauramaa R. 2006. Diabetes care. 29: 931-932 A2 Review article, Literature review, Systematic review -
Different forms of physical activity and cardiovascular risk factors among 24-64-year-old men and women in Finland
Barengo NC, Kastarinen M, Lakka T, Nissinen A, Tuomilehto J. 2006. EUROPEAN JOURNAL OF CARDIOVASCULAR PREVENTION AND REHABILITATION. 13: 51-59 A1 Journal article (refereed), original research -
Exercise, genetics and prevention of type 2 diabetes
Hu G, Rico-Sanz J, Lakka TA, Tuomilehto J. 2006. Essays in biochemistry. 42: 177-192 A1 Journal article (refereed), original research -
Heart rate response during exercise test and cardiovascular mortality in middle-aged men
Savonen KP, Lakka TA, Laukkanen JA, Halonen PM, Rauramaa TH, Salonen JT, Rauramaa R. 2006. European heart journal. 27: 582-588 A1 Journal article (refereed), original research -
High dietary methionine intake increases the risk of acute coronary events in middle-aged men
Virtanen JK, Voutilainen S, Rissanen TH, Happonen P, Mursu J, Laukkanen JA, Poulsen H, Lakka TA, Salonen JT. 2006. Nutrition metabolism and cardiovascular diseases. 16: 113-120 A1 Journal article (refereed), original research -
Letter to the editor (Exercise and inflammation: reply)
Lakka TA, Lakka H-M, Rankinen T, Bouchard C. 2006. European heart journal -
Lifestyle management in the metabolic syndrome
Hu G, Lakka TA, Lakka H-M, Tuomilehto J. 2006. Metabolic syndrome and related disorders. 4: 270-286 A2 Review article, Literature review, Systematic review -
Metabolic syndrome and the progression of carotid intima-media thickness in elderly women
Hassinen M, Komulainen P, Lakka TA, Väisänen SB, Haapala I, Gylling H, Alen M, Schmidt-Trucksäss A, Nissinen A, Rauramaa R. 2006. Archives of internal medicine. 166: 444-449 A1 Journal article (refereed), original research -
Peak oxygen pulse during exercise as a predictor for coronary heart disease and all cause death
Laukkanen JA, Kurl S, Salonen JT, Lakka TA, Rauramaa R. 2006. Heart. 92: 1219-1224 A1 Journal article (refereed), original research -
Quantitative trait locus on chromosme 20q13 for plasma levels of C-reactive protein in healthy whites: the HERITAGE family sudy
Lakka TA, Rankinen T, Rice T, Leon AS, Rao DC, Skinner JS, Bouchard C. 2006. Physiological genomics. 27: 103-107 A1 Journal article (refereed), original research -
Systemic immune mediators and lifestyle changes in the prevention of type 2 diabetes. Results from the Finnish diabes prevention study
Herder C, Peltonen M, Koenig W, Kräft I, Mûller-Scholze S, Martin S, Lakka T, Ilanne-Parikka P, Eriksson JG, Hämäläinen H, Keinänen-Kiukaanniemi S, Valle TT, Uusitupa M, Lindström J, Kolb H, Tuomilehto J. 2006. Diabetes. 55: 2340-2346 A1 Journal article (refereed), original research -
The TNF-a G-308A polymorphism is associated with C-reactive protein levels: The HERITAGE Family Study
Lakka H-M, Lakka TA, Rankinen T, Rice T, Rao DC, Leon AS, Skinner JS, Bouchard C. 2006. Vascular pharmacology. 44: 377-383 A1 Journal article (refereed), original research -
Associations between estimated aerobic fitness and cardiovascular risk factors in adults with different levels of abdominal obesity
Borodulin K, Laatikainen T, Lahti-Koski M, Lakka TA, Laukkanen R, Sarna S, Jousilahti P. 2005. EUROPEAN JOURNAL OF CARDIOVASCULAR PREVENTION AND REHABILITATION. 12: 126-131 A1 Journal article (refereed), original research -
Associations of body composition and physical activity with balance and walking ability in the elderly
Hassinen M, Komulainen P, Lakka TA, Väisänen SB, Rauramaa R. 2005. Journal of physical activity and health. 3: 298-306 A1 Journal article (refereed), original research -
Effect of exercise training on plasma levels of C-reactive protein in healthy adults: the HERITAGE family study
Lakka TA, Lakka H-M, Rankinen T, Leon AS, Rao DC, Skinner JS, Wilmore JH, Bouchard C. 2005. European heart journal. 26: 2018-2025 A1 Journal article (refereed), original research -
Effects of exercise training on glucose homeostasis. The Heritage family studies
Boulé NG, Weisnagel SJ, Lakka TA, Tremblay A, Bergman RN, Rankinen T, Leon AS, Skinner JS, Wilmore JH, Rao DC, Bouchard C. 2005. Diabetes care. 28: 108-114 A1 Journal article (refereed), original research -
Low physical activity as a predictor for antihypertensive drug treatment in 25- 64-year-old populations in Eastern and south-western Finland
Barengo NC, Hu G, Kastarinen M, Lakka TA, Pekkarinen H, Nissinen A, Tuomilehto J. 2005. Journal of hypertension. 23: 293-299 A1 Journal article (refereed), original research -
Physical activity in the prevention of type 2 diabetes. The Finnish diabetes prevention study
Laaksonen DE, Lindström J, Lakka TA, Eriksson JG, Niskanen L, Wikström K, Aunola S, Keinänen-Kiukaanniemi S, Laakso M, Valle TT, Ilanne-Parikka P, Louheranta A, Hakumäki M, Kaikkonen H, Härkönen P, Sundvall J, Tuomilehto J, Uusitupa M, Louheranta A. 2005. Diabetes. 54: 158-165 A1 Journal article (refereed), original research -
Physical activity, cardiovascular risk factors, and mortality among Finnish adults with diabetes
Hu G, Jousilahti P, Barengo NC, Qiao Q, Lakka TA, Tuomilehto J. 2005. Diabetes care. 28: 799-805 A1 Journal article (refereed), original research -
Protein tyrosine phosphatase 1B variant associated with fat distribution and insulin metabolism
Ukkola O, Rankinen T, Lakka T, Leon AS, Skinner JS, Wilmore JH, Rao DC, Kesäniemi YA, Bouchard C. 2005. Obesity. 13: 829-834 A1 Journal article (refereed), original research -
Epidemiology and treatment of the metabolic syndrome
Laaksonen DE, Niskanen L, Lakka H-M, Lakka TA, Uusitupa M, Laaksonen DE. 2004. Annals of medicine. 36: 332-346 A2 Review article, Literature review, Systematic review -
Low physical activity as a predictor for total and cardiovascular disease mortality in middle-aged men and women in Finland
Barengo NC, Hu G, Lakka TA, Pekkarinen H, Nissinen A, Tuomilehto J. 2004. European heart journal. 25: 2204-2211 A1 Journal article (refereed), original research -
Physical activity in the prevention of type 2 diabetes
Hu G, Lakka TA, Barengo NC, Tuomilehto J. 2004. KARDIOVASKULÄRE MEDIZIN. 7: 394-405 A1 Journal article (refereed), original research -
Relationship of physical activity and body mass index to the risk of hypertension: a prospective study in Finland
Hu G, Barengo NC, Tuomilehto J, Lakka TA, Nissinen A, Jousilahti P. 2004. Hypertension. 43: 25-30 A1 Journal article (refereed), original research -
Systolic blood pressure during recovery from exercise and the risk of acute myocardial infarction in middle-aged men
Laukkanen JA, Kurl S, Salonen R, Lakka TA, Rauramaa R, Salonen JT. 2004. Hypertension. 44: 820-825 A1 Journal article (refereed), original research -
Cardiorespiratory fitness and vigorous leisure-time physical activity modify the association of small size at birth with the metabolic syndrome
Laaksonen DE, Lakka H-M, Lynch J, Lakka TA, Niskanen L, Rauramaa R, Salonen JT, Kauhanen J. 2003. Diabetes care. 26: 2156-2164 A1 Journal article (refereed), original research -
Sedentary lifestyle, poor cardiorespiratory fitness, and the metabolic syndrome
Lakka TA, Laaksonen DE, Lakka H-M, Männikkö N, Niskanen LK, Rauramaa R, Salonen JT. 2003. Medicine and science in sports and exercise. 35: 1279-1286 A1 Journal article (refereed), original research -
Abdominal obesity is associated with accelerated progression of carotid atherosclerosis in men
Lakka TA, Lakka H-M, Salonen R, Kaplan GA, Salonen JT. 2001. Atherosclerosis. 154: 497-504 A1 Journal article (refereed), original research -
Cardiovascular fitness as a predictor of mortality in men
Laukkanen JA, Lakka TA, Rauramaa R, Kuhanen R, Venäläinen JM, Salonen R, Salonen JT. 2001. Archives of internal medicine. 161: 825-831 A1 Journal article (refereed), original research -
Leisure-time physical activity and rate of bone loss among peri- and postmenopausal women: a longitudinal study
Puntila E, Kröger H, Lakka T, Tuppurainen M, Jurvelin J, Honkanen R. 2001. Bone. 29: 442-446 A1 Journal article (refereed), original research -
Liikuntaa sepelvaltimotaudin ehkäisyyn ja hoitoon
Rauramaa R, Lakka TA. 2001. Duodecim. 117: 633-638 A2 Review article, Literature review, Systematic review -
Low dietary folate intake is associated with an excess incidence of acute coronary events. The Kuopio Ischemic Heart Disease Risk Factor Study
Voutilainen S, Rissanen TH, Virtanen J, Lakka TA, Salonen JT. 2001. Circulation. 103: 2674-2680 A1 Journal article (refereed), original research -
Risk of acute coronary events and serum concentration of asymmetrical dimethylarginine
Valkonen V-P, Päivä H, Salonen JT, Lakka TA, Lehtimäki T, Laakso J, Laaksonen R. 2001. The Lancet. 358: 2127-2128 A1 Journal article (refereed), original research -
Low serum folate concentrations are associated with an excess incidence of acute coronary events: the Kuopio Ischaemic Heart Disease Risk Factor Study
Voutilainen S, Lakka TA, Porkkala-Sarataho E, Rissanen T, Kaplan GA, Salonen JT. 2000. European journal of clinical nutrition. 54: 424-428 A1 Journal article (refereed), original research -
Risk of acute coronary events according to serum concentrations of enterolactone: a prospective population-based case-control study
Vanharanta M, Voutilainen S, Lakka TA, van der Lee M, Adlercreutz H, Salonen JT. 1999. The Lancet. 354: 2112-2115 A1 Journal article (refereed), original research -
Hyperinsulinemia is associated with the incidence of hypertension and dyslipidemia in middle-aged men
Salonen JT, Lakka TA, Lakka H-M, Valkonen V-P, Everson SA, Kaplan GA. 1998. Diabetes. 47: 270-275 A1 Journal article (refereed), original research -
Weight gain and the risk of developing insulin resistance syndrome
Everson SA, Goldberg DE, Helmrich SP, Lakka TA, Lynch JW, Kaplan GA, Salonen JT. 1998. Diabetes care. 21: 1637-1643 A1 Journal article (refereed), original research -
Body iron stores are associated with serum insulin and blood glucose concentrations
Tuomainen T-P, Nyyssönen K, Salonen R, Tervahauta A, Korpela H, Lakka T, Kaplan GA, Salonen JT. 1997. Diabetes care. 20: 426-428 A1 Journal article (refereed), original research -
Frequent hangovers and cardiovascular mortality in middle-aged men
Kauhanen J, Kaplan GA, Goldberg DD, Cohen RD, Lakka TA, Salonen JT. 1997. Epidemiology. 8: 310-314 A1 Journal article (refereed), original research -
Physical activity in adolescence and bone density in peri- and postmenopausal women: A population-based study
Puntila E, Kröger H, Lakka T, Honkanen R, Tuppurainen M. 1997. Bone. 21: 363-367 A1 Journal article (refereed), original research -
The physical activity questionnaires of the Kuopio Ischemic Heart Disease Risk Factor Study (KIHD)
Lakka TA, Salonen JT. 1997. MEDICINE AND SCIENCE IN SPORTS AND EXERCISE. SUPPLEMENT. 29: S46-S58 A1 Journal article (refereed), original research -
Conditioning leisure time physical activity and cardiorespiratory fitness in sociodemographic groups of middle-aged men in Eastern Finland
Lakka TA, Kauhanen J, Salonen JT. 1996. International journal of epidemiology. 25: 86-93 A1 Journal article (refereed), original research -
Hyperinsulinemia and the risk of coronary heart disease
Lakka TA, Lakka H-M, Salonen JT. 1996. The new england journal of medicine -
Moderately intense physical activities and high levels of cardiorespiratory fitness reduce the risk of non-insulin-dependent diabetes mellitus in middle-aged men
Lynch J, Helmrich SP, Lakka TA, Kaplan GA, Cohen RD, Salonen R, Salonen JT. 1996. Archives of internal medicine. 156: 1307-1314 A1 Journal article (refereed), original research -
Religious affiliation and all-cause mortality: a prospective population study in middle-aged men in Eastern Finland
Räsänen J, Kauhanen J, Lakka TA, Kaplan GA, Salonen JT. 1996. International journal of epidemiology. 25: 1244-1249 A1 Journal article (refereed), original research -
Higher levels of conditioning leisure time physical activity are associated with reduced levels of stored iron in Finnish men
Lakka TA, Nyyssönen K, Salonen JT. 1994. American journal of epidemiology. 140: 148-160 A1 Journal article (refereed), original research -
Relation of leisure-time physical activity and cardiorespiratory fitness to the risk of acute myocardial infarction in men
Lakka TA, Venäläinen JM, Rauramaa R, Salonen R, Tuomilehto J, Salonen JT. 1994. The new england journal of medicine. 330: 1549-1554 A1 Journal article (refereed), original research