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Reino Laatikainen

Reino Laatikainen

Professor, Emeritus

School of Pharmacy, Faculty of Health Sciences

[email protected] | +358 40 355 3248

Information Publications

Publications

77/77 items

21Ne and 131Xe NMR study of electric field gradients and multinuclear NMR study of the composition of a ferroelectric liquid crystal
Ahola, Susanna K; Ingman, Petri; Laatikainen, Reino; Sinkkonen, Jari; Jokisaari, Jukka. 2018. Journal of chemical physics. 149: 234901 A1 Journal article (refereed), original research
Biowaste Conversion into Carboxylate Platform Chemicals
den Boer Emilia, Lukaszewska Agnieszka, Kluczkiewicz Wladyslaw, Lewandowska Daria, King Kevin, Jääskeläinen Ari, Heitto Anneli, Laatikainen Reino, Hakalehto Elias. Teoksessa: Eino Elias Hakalehto(toim.) , 2016. Microbiological Industrial Hygiene. s. 231-247. Nova science publishers A3 Book section, Chapters in research books
Forest Industry Hygiene Control with Reference to Waste Refinement
Hakalehto Elias, Heitto Anneli, Niska Harri, Suhonen Anssi, Laatikainen Reino, Heitto Lauri, Antikainen Eero, Jääskeläinen Ari. Teoksessa: Eino Elias Hakalehto(toim.) , 2016. Microbiological Industrial Hygiene. s. 151-185. Nova science publishers A3 Book section, Chapters in research books
Meat Industry Hygiene, Outlines of Safety and Material Recycling by Biotechnological Means
Hakalehto Elias, Heitto Anneli, Kivelä Jukka, Laatikainen Reino. Teoksessa: Eino Elias Hakalehto(toim.) , 2016. Microbiological Industrial Hygiene. s. 249-270. Nova science publishers A3 Book section, Chapters in research books
Quantitative quantum mechanical NMR analysis: the superior tool for analysis of biofluids
Laatikainen Reino, Laatikainen Pekka, Hakalehto Elias. Teoksessa: (toim.) , 2016. . s. C005. MDPI AG A4 Conference proceedings
Some Remarks on Processing of Slaughterhouse Wastes from Ecological Chicken Abattoir and Farm
Hakalehto Elias, Heitto Anneli, Andersson Henny, Lindmark Johan, Jansson Joakim, Reijonen Tero, Suhonen Anssi, Jääskeläinen Ari, Laatikainen Reino, Schwede Sebastian, Klintenberg Patrik, Thorin Eva. Teoksessa: Eino Elias Hakalehto(toim.) , 2016. Microbiological Industrial Hygiene. s. 271-293. Nova science publishers A3 Book section, Chapters in research books
Using slaughterhouse waste in a biochemical-based biorefinery - results from pilot scale tests
Schwede Sebastian, Thorin Eva, Lindmark Johan, Klintenberg Patrik, Jääskeläinen Ari, Suhonen Anssi, Laatikainen Reino, Hakalehto Elias. 2016. Environmental technology. 2017; 38: 1275-1284 A1 Journal article (refereed), original research
Volatile fatty acids as an added value from biowaste
den Boer Emilia, Lukaszewska Agnieszka, Kluczkiewicz Wladyslaw, Lewandowska Daria, King Kevin, Reijonen Tero, Kuhmonen Tero, Suhonen Anssi, Jääskeläinen Ari, Heitto Anneli, Laatikainen Reino, Hakalehto Elias. 2016. Waste management. 58: 62-69 A1 Journal article (refereed), original research
Comprehensive strategy for proton chemical shift prediction: linear prediction with nonlinear corrections
Laatikainen Reino, Hassinen Tommi, Lehtivarjo Juuso, Tiainen Mika, Jungman Juha, Tynkkynen Tuulia, Korhonen Samuli-Petrus, Niemitz Matthias, Poutiainen Pekka, Jääskeläinen Olli, Väisänen Topi, Weisell Janne, Soininen Pasi, Laatikainen Pekka, Martonen Henri, Tuppurainen Kari. 2014. Journal of chemical information and modeling. 54: 419-430 A1 Journal article (refereed), original research
Preclinical pharmacology of FL442, a novel nonsteroidal androgen receptor modulator
Poutiainen Pekka K, Huhtala Tuulia, Jääskeläinen Tiina, Petsalo Aleksanteri, Küblbeck Jenni, Kaikkonen Sanna, Palvimo Jorma J, Raunio Hannu, Närvänen Ale, Peräkylä Mikael, Juvonen Risto O, Honkakoski Paavo, Laatikainen Reino, Pulkkinen Juha T. 2014. Molecular and cellular endocrinology. 387: 8-18 A1 Journal article (refereed), original research
Quantitative Quantum Mechanical Spectral Analysis (qQMSA) of (1)H NMR spectra of complex mixtures and biofluids
Tiainen Mika, Soininen Pasi, Laatikainen Reino. 2014. Journal of magnetic resonance. 242: 67-78 A1 Journal article (refereed), original research
Discovery of 5-benzyl-3-phenyl-4,5-dihydroisoxazoles and 5-benzyl-3-phenyl-1,4,2-dioxazoles as potent firefly luciferase inhibitors
Poutiainen Pekka K, Palvimo Jorma J, Hinkkanen Ari E, Valkonen Arto, Väisänen Topi K, Laatikainen Reino, Pulkkinen Juha T. 2013. Journal of medicinal chemistry. 56: 1064-1073 A1 Journal article (refereed), original research
Firefly luciferase inhibitor-conjugated peptide quenches bioluminescence: a versatile tool for real time monitoring cellular uptake of biomolecules
Poutiainen Pekka K, Rönkkö Teemu, Hinkkanen Ari E, Palvimo Jorma J, Närvänen Ale, Turhanen Petri, Laatikainen Reino, Weisell Janne, Pulkkinen Juha T. 2013. Bioconjugate chemistry. 2014:25: 4-10 A1 Journal article (refereed), original research
MetIDB: a publicly accessible database of predicted and experimental 1H NMR spectra of flavonoids
Mihaleva Velitchka V, te Beek Tim A, van Zimmeren Frank, Moco Sofia, Laatikainen Reino, Niemitz Matthias, Korhonen Samuli-Petrus, van Driel Marc A, Vervoort Jacques. 2013. Analytical chemistry. 85: 8700-8707 A1 Journal article (refereed), original research
Novel non-steroidal compounds as androgen receptor modulators
Pulkkinen Juha, Poutiainen Pekka, Oravilahti Tuomas, Palvimo Jorma, Peräkylä Mikael, Laatikainen Reino, Ihalainen Tarja. 2013. H1 Granted patent
¹H-NMR fingerprinting of Vaccinium vitis-idaea flavonol glycosides
Riihinen Kaisu R, Mihaleva Velitchka V, Gödecke Tanja, Soininen Pasi, Laatikainen Reino, Vervoort Jacques M, Lankin David C, Pauli Guido F. 2013. Phytochemical analysis. 24: 476-483 A1 Journal article (refereed), original research
Combining NMR ensembles and molecular dynamics simulations provides more realistic models of protein structures in solution and leads to better chemical shift prediction
Lehtivarjo Juuso, Tuppurainen Kari, Hassinen Tommi, Laatikainen Reino, Peräkylä Mikael. 2012. Journal of biomolecular nmr. 52: 257-267 A1 Journal article (refereed), original research
Design, synthesis and biological evaluation of nonsteroidal cycloalkane[d]isoxazole-containing androgen receptor modulators
Poutiainen Pekka, Oravilahti Tuomas, Peräkylä Mikael, Palvimo Jorma, Ihalainen Janne, Laatikainen Reino, Pulkkinen Juha. 2012. Journal of medicinal chemistry. 55: 6316-6327 A1 Journal article (refereed), original research
High-throughput quantification of circulating metabolites improves prediction of subclinical atherosclerosis
Würtz Peter, Raiko Juho R, Magnussen Costan G, Soininen Pasi, Kangas Antti J, Tynkkynen Tuulia, Thomson Russell, Laatikainen Reino, Savolainen Markku J, Laurikka Jari, Kuukasjärvi Pekka, Tarkka Matti, Karhunen Pekka J, Jula Antti, Viikari Jorma S, Kähönen Mika, Lehtimäki Terho, Juonala Markus, Ala-Korpela Mika, Raitakari Olli T. 2012. European heart journal. 33: 2307-2316 A1 Journal article (refereed), original research
Metabolic Diversity of Progressive Kidney Disease in 325 Patients with Type 1 Diabetes (the FinnDiane Study)
Mäkinen VP, Tynkkynen T, Soininen P, Peltola T, Kangas AJ, Forsblom C, Thorn LM, Kaski K, Laatikainen R, Ala-Korpela M, Groop PH. 2012. Journal of proteome research. 11: 1782-1790 A1 Journal article (refereed), original research
Molecular dynamics simulations for human CAR inverse agonists
Jyrkkärinne Johanna, Küblbeck Jenni, Pulkkinen Juha, Honkakoski Paavo, Laatikainen Reino, Poso Antti, Laitinen Tuomo. 2012. Journal of chemical information and modeling. 52: 457-464 A1 Journal article (refereed), original research
¹H NMR spectral analysis and conformational behavior of n-alkanes in different chemical environments
Tynkkynen Tuulia, Hassinen Tommi, Tiainen Mika, Soininen Pasi, Laatikainen Reino. 2012. Magnetic resonance in chemistry. 50: 598-607 A1 Journal article (refereed), original research
Computerized Analysis of High-resolution Solution-state Spectra
Laatikainen Reino, Tiainen Mika, Korhonen Samuli-Petrus, Niemitz Matthias. 2011. Magnetic resonance in chemistry. . John Wiley C2 Edited book, conference proceedings or special issue of a journal
NMR protocol for determination of oxidation susceptibility of serum lipids and application of the protocol to a chocolate study
Tynkkynen Tuulia, Mursu Jaakko, Nurmi Tarja, Tuppurainen Kari, Laatikainen Reino, Soininen Pasi. 2011. Metabolomics. 8: 386-398 A1 Journal article (refereed), original research
13C Isotope Effects on 1H Chemical Shifts: NMR Spectral Analysis of 13C-Labelled D-glucose and Some 13C-Labelled Amino Acids
Tiainen M, Maaheimo H, Soininen P & Laatikainen R. 2010. Magnetic resonance in chemistry. 48(2): 117-122 A1 Journal article (refereed), original research
Screening of binding activity of Streptococcus pneumoniae, Streptococcus agalactiae and Streptococcus suis to berries and juices
Toivanen M, Huttunen S, Duricová J, Soininen P, Laatikainen R, Loimaranta V, Haataja S, Finne J, Lapinjoki S & Tikkanen-Kaukanen C. 2010. Phytotherapy research. 24: S95 - S101 A1 Journal article (refereed), original research
Sex hormones and their analogues in neuroimmune biology.
Berczi, I.; Laatikainen, R.; Pulkkinen, J.. 2010. Immunology, endocrine and metabolic agents in medicinal chemistry. 10: 142-181 A2 Review article, Literature review, Systematic review
Synthesis and biological evaluation of phenolic 4,5-dihydroisoxazoles and 3-hydroxy ketones as estrogen receptor alpha and beta agonists
Poutiainen, Pekka K.; Venäläinen, Tuomas A.; Peräkylä, Mikael; Matilainen, Juha M.; Väisänen, Sami; Honkakoski, Paavo; Laatikainen, Reino; Pulkkinen, Juha T. 2010. Bioorganic and medicinal chemistry. 18: 3437-3447 A1 Journal article (refereed), original research
4D prediction of protein 1H chemical shifts
Lehtivarjo J, Hassinen T, Korhonen S-P, Peräkylä M, Laatikainen R. 2009. . 45: 413-426 A1 Journal article (refereed), original research
High-throughput serum NMR metabonomics for cost effect holistic studies on systematic metabolism
Soininen P, Kangas AJ, Würtz P, Tukiainen T, Tynkkynen T, Laatikainen R, Järvelin M-R, Kähönen M, Lehtimäki T, Viikari J, Raitakari OT, Savolainen MJ, Ala-Korpela M. 2009. Analyst. : 1781-1785 A1 Journal article (refereed), original research
NMR and UPLC-qTOF-MS/MS characterisation of novel phenylethanol derivates of phenylpropanoid glucosides from the leaves of strawberry (Fragaria x ananassa cv. Jonsok)
Hanhineva K, Soininen P, Anttonen MJ, Kokko H, Rogachev I, Aharoni A, Laatikainen R, Kärenlampi S. 2009. Phytochemical analysis. : 353-364 A1 Journal article (refereed), original research
NMR and UPLC-qTOF-MS/MS characterisation of novel phenylethanol derivatives of phenylpropanoid glucosides from the leaves of strawberry (Fragaria x ananassa cv. Jonsok)
Hanhineva K, Soininen P, Anttonen MJ, Kokko H, Rogachev I, Aharoni A, Laatikainen R & Kärenlampi S. 2009. Phytochemical analysis. 20: 353-364 A1 Journal article (refereed), original research
Novel 4,5-dihydroisoxazoles with estrogenic activity
Pulkkinen J, Honkakoski P, Peräkylä M, Berczi I, Laatikainen R. 2009. H1 Granted patent
Novel beta-hydroxyketones and beta-alkoxyketones with estrogenic activity
Pulkkinen J, Honkakoski P, Peräkylä M, Berczi I, Laatikainen R. 2009. H1 Granted patent
Stilbene synthase gene transfer resulted in down regulation of endogenous chalcone synthase in strawberry (Fragaria x ananassa) and led to the identification of novel phenylpropanoid glucosides
Hanhineva K, Anttonen MJ, Kokko H, Soininen P, Laatikainen R, Kärenlampi S, Rogachev I, Aharoni A. Teoksessa: Hanke M-V, Dunemann F, Flachowsky H(toim.) , 2009. Proceedings of the First International Symposium on Biotechnology of Fruit Species Bioftechfruit 2008. s. 673-679. International Society for Horticultural Science A4 Conference proceedings
A multi-metabolite analysis of serum by 1H NMR spectroscopy: Early systemic signs of Alzheimer's disease
Tukiainen T, Tynkkynen T, Mäkinen V-P, Jylänki P, Kangas A, Hokkanen J, Vehtari A, Gröhn O, Hallikainen M, Soininen H, Kivipelto M, Groop P-H, Kaski K, Laatikainen R, Soininen P, Pirttilä T, Ala-Korpela M, Soininen H, Pirttilä. 2008. Biochemical and biophysical research communications. 375: 356-361 A1 Journal article (refereed), original research
Ligand specificity of constitutive androstane receptor as probed by induced-fit drocking and mutagenesis
Repo S, Jyrkkärinne J, Pulkkinen JT, Laatikainen R, Honkakoski P, Johnson MS. 2008. Journal of medicinal chemistry. 51: 7119-7131 A1 Journal article (refereed), original research
Quantification of 1H NMR spectra of human cerebrospinal fluid: a protocol based on constrained total-line-shape analysis
Jukarainen NM, Korhonen S-P, Laakso MP, Korolainen MA, Niemitz M, Soininen PP, Tuppurainen K, Vepsäläinen J, Pirttilä T, Laatikainen R, Pirttilä T. 2008. Metabolomics. 4: 150-160 A1 Journal article (refereed), original research
Spectral analysis of 1H coupled 13C spectra of the amino acids: adaptive spectral library of amino acid 13C isotopomers and positional fractional 13C enrichments
Tiainen M, Maaheimo H, Niemitz M, Soininen P, Laatikainen R. 2008. Magnetic resonance in chemistry. 46: 125-137 A1 Journal article (refereed), original research
Synthesis and evaluation of estrogen agonism of diaryl 4,5-dihydroisoxazoles, 3-hydroxyketones, 3-methoxyketones, and 1,3-diketones: A compound set forming a 4D molecular library
Pulkkinen JT, Honkakoski P, Peräkylä M, Berczi I, Laatikainen R. 2008. Journal of medicinal chemistry. 51: 3562-3571 A1 Journal article (refereed), original research
1H NMR at 800 MHz facilitates detailed phospholipid follow-up during atherogenic modifications in low density lipoproteins
Soininen P, Öörni K, Maaheimo H, Laatikainen R, Kovanen PT, Kaski K, Ala-Korpela M. 2007. Biochemical and biophysical research communications. 360: 290-294 A1 Journal article (refereed), original research
1H NMR metabonomics of plasma lipoprotein subclasses: elucidation of metabolic clustering by self-organising maps
Suna T, Salminen A, Soininen P, Laatikainen R, Ingman P, Mäkelä S, Savolainen MJ, Hannuksela ML, Jauhiainen M, Taskinen M-R, Kaski K, Ala-Korpela M. 2007. Nmr in biomedicine. 20: 658-672 A1 Journal article (refereed), original research
Complete 1H NMR spectral fingerprint of huperzine A
Niemitz M, Laatikainen R, Chen S-N, Kleps R, Kozikowski AP, Pauli GF. 2007. Magnetic resonance in chemistry. 45: 878-882 A1 Journal article (refereed), original research
The inherent accuracy of 1H NMR spectroscopy to quantify plasma lipoproteins is subclass dependent
Ala-Korpela M, Lankinen N, Salminen A, Suna T, Soininen P, Laatikainen R, Ingman P, Jauhiainen M, Taskinen M-R, Héberger K, Kaski K. 2007. Atherosclerosis. 190: 352-358 A1 Journal article (refereed), original research
Beta-amyloid infusion results in delayed and age-dependent learning deficits without role of inflammation or beta-amyloid deposits
Malm T, Ort M, Tähtivaara L, Jukarainen N, Goldsteins G, Puoliväli J, Nurmi A, Pussinen R, Ahtoniemi T, Miettinen T-K, Kanninen K, Leskinen S, Vartiainen N, Yrjänheikki J, Laatikainen R, Harris-White ME, Koistinaho M, Frautschy SA, Bures J. 2006. Proceedings of the National Academy of Sciences of the United States of America. 103: 8852-8857 A1 Journal article (refereed), original research
Improving the performance of SOMFA by use of standard multivariate methods
Korhonen SP, Tuppurainen K, Laatikainen R, Peräkylä M. 2005. Sar and qsar in environmental research. 16: 567-579 A1 Journal article (refereed), original research
Strategies for organic impurity quantification by 1H NMR spectroscopy: constrained total-line-shape fitting
Soininen P, Haarala J, Vepsäläinen J, Niemitz M, Laatikainen R. 2005. Analytica chimica acta. 542: 178-185 A1 Journal article (refereed), original research
Application of novel metallocomplexes for mimicking of cytochrome P450 analysis of product distribution for 1-hexene as a substrate
Pulkkinen J, Zachar P, Borek VA, Laatikainen R, Kral V. 2004. Journal of molecular catalysis A : chemical. 219: 21-27 A1 Journal article (refereed), original research
Determination of the degree of substitution of acetylated starch by hydrolysis, 1H NMR and TGA/IR
Elomaa M, Asplund T, Soininen P, Laatikainen R, Peltonen S, Hyvärinen S, Urtti A. 2004. Carbohydrate polymers. : 261-267 A1 Journal article (refereed), original research
Ligand intramolecular motions in ligand-protein interaction: ALPHA, a novel dynamic descriptor and a QSAR study with extended steroid benchmark dataset
Tuppurainen K, Viisas M, Peräkylä M, Laatikainen R. 2004. Journal of computer-aided molecular design. 18: 175-187 A1 Journal article (refereed), original research
FLUFF-BALL, a template-based grid-independent superposition and QSAR technique: validation using a benchmark steroid data set
Korhonen S-P, Tuppurainen K, Laatikainen R, Peräkylä M. 2003. JOURNAL OF CHEMICAL INFORMATION AND COMPUTER SCIENCES (WASHINGTON). 43: 1780-1793 A1 Journal article (refereed), original research
Reduction of 6/7-substituted 3-phenyltrop-3-en-2-ones: stereoselectivity and conformational analysis of the products
Airaksinen AJ, Lipsonen J, Ahlgren M, Vainiotalo P, Bergström KA, Laatikainen R, Vepsäläinen J. 2003. Tetrahedron. 59: 377-383 A1 Journal article (refereed), original research
Antioxidant and antitumor effects of hydroxymatairesinol (HM-3000, HMR), a lignan isolated from the knots of spruce
Kangas L, Saarinen N, Mutanen M, Ahotupa M, Hirsinummi R, Unkila M, Perälä M, Soininen P, Laatikainen R, Korte H, Santti R. 2002. European journal of cancer prevention. 11: S48-S57 A1 Journal article (refereed), original research
Correlative motions and memory effects in molecular dynamics simulations of molecules: principal components and rescaled range analysis suggest that the motions of native BPTI are more correlated than those of its mutants
Saarela JTA, Tuppurainen K, Peräkylä M, Santa H, Laatikainen R. 2002. Biophysical chemistry. 95: 49-57 A1 Journal article (refereed), original research
Evaluation of a novel electronic eigenvalue (EEVA) molecular descriptor for QSAR/QSPR studies: Validation using a benchmark steroid data set
Tuppurainen K, Viisas M, Laatikainen R, Peräkylä M. 2002. JOURNAL OF CHEMICAL INFORMATION AND COMPUTER SCIENCES (WASHINGTON). 42: 607-613 A1 Journal article (refereed), original research
Isolation and identification of Aspergillus fumigatus mycotoxins on growth medium and some building materials
Nieminen SM, Kärki R, Auriola S, Toivola M, Laatsch H, Laatikainen R, Hyvärinen A, Von Wright A. 2002. Applied and environmental microbiology. 68: 4871-4875 A1 Journal article (refereed), original research
Stability and amino acid preferences of type VIII reverse turn: the most common turn in peptides?
Santa H, Ylisirniö M, Hassinen T, Laatikainen R, Peräkylä M. 2002. Protein engineering design and selection. 15: 651-657 A1 Journal article (refereed), original research
Synthesis and antimicrobial activity of the symmetric dimeric form of tetmporin a based on 3-N,N-di(3-aminopropyl)amino propanoic acid as the branching unit
Hujakka H, Ratilainen J, Korjamo T, Lankinen H, Kuusela P, Santa H, Laatikainen R, Närvänen A. 2001. Bioorganic and medicinal chemistry. 9: 1601-1607 A1 Journal article (refereed), original research
A proton relay process as the mechanism of activation of the histamine H3-receptor determined by 1H NMR and ab initio quantum mechanical calculations
Kovalainen JT, Christiaans JAM, Ropponen R, Poso A, Peräkylä M, Vepsäläinen J, Laatikainen R, Gynther J. 2000. Journal of the American Chemical Society. 122: 6989-6996 A1 Journal article (refereed), original research
Conformational flexibility and role of aromatic-aromatic interactions in the crystal packing of the coordination compounds of some novel quadridentate Schiff bases
Pulkkinen JT, Laatikainen R, Ahlgrén MJ, Peräkylä M, Vepsäläinen JJ. 2000. JOURNAL OF THE CHEMICAL SOCIETY. PERKIN 2. 2: 777-784 A1 Journal article (refereed), original research
Effect of supplementation with organic selenium on mercury status as measured by mercury in pubic hair
Seppänen K, Kantola M, Laatikainen R, Nyyssönen K, Valkonen V-P, Kaarlöpp V, Salonen JT. 2000. Journal of trace elements in medicine and biology. 14: 84-87 A1 Journal article (refereed), original research
Oligonucleotides containing 9-(2-deoxy-2-fluoro-beta-d-arabinofuranosyl)-adenine and -guanine: synthesis, hybridization and antisense properties
Tennilä T, Azhayeva E, Vepsäläinen J, Laatikainen R, Azhayev A, Mikhailopulo IA. 2000. Nucleosides nucleotides and nucleic acids. 19: 1861-1884 A1 Journal article (refereed), original research
1H NMR study on putative intramolecular hydrogen bonding for histamine H3-receptor agonists
Kovalainen JT, Christiaans JAM, Poso A, Vepsäläinen J, Laatikainen R, Gynther J. 1999. Tetrahedron letters. 40: 2425-2428 A1 Journal article (refereed), original research
Characterization of a conformationally flexible system: NMR spectroscopic study of 1,5-diphenylpentane-2,4-dione
Pulkkinen JT, Laatikainen R, Vepsäläinen JJ, Ahlgrén MJ. 1999. Magnetic resonance in chemistry. 37: 119-126 A1 Journal article (refereed), original research
Folding of alfarbeta and ethabeta reverse turns: a nanosecond molecular dynamics simulation of the hexapeptide MSALNT and octapeptide NMSALNTL in water
Santa H, Peräkylä M, Laatikainen R. 1999. Journal of biomolecular structure and dynamics. 16: 1033-1041 A1 Journal article (refereed), original research
Nuclear magnetic resonance and molecular orbital study of some cocaine analogues
Airaksinen AJ, Tuppurainen KA, Lötjönen SE, Niemitz M, Yu M, Vepsäläinen JJ, Laatikainen R, Hiltunen J, Bergström KA. 1999. Tetrahedron. 55: 10537-10546 A1 Journal article (refereed), original research
Solvent dependence of rotational energetics and formyl-proton long-range spin-spin coupling behavior of 2,6-dichloro- and 2,6-dinitrobenzaldehydes using dipolar couplings and temperature dependence of long-range couplings
Lounila J, Hiltunen Y, Tuppurainen K, Pulkkinen A, Laatikainen R. 1999. Canadian journal of chemistry. 77: 1788-1796 A1 Journal article (refereed), original research
A bovine dander allergen, comparative modeling, and similarities and differences in folding with related proteins
Santa H, Saarela JTA, Laatikainen R, Rautiainen J, Virtanen T, Rytkönen M, Mäntyjärvi R. 1998. Protein journal. 17: 657-662 A1 Journal article (refereed), original research
Internal motions of native lysozyme are more organized than those of mutants: a principal component analysis of molecular dynamics data
Laatikainen R, Saarela J, Tuppurainen K, Hassinen T. 1998. Biophysical chemistry. 73: 1-5 A1 Journal article (refereed), original research
Mercury-binding capacity of organic and inorganic selenium in rat blood and liver
Seppänen K, Laatikainen R, Salonen JT, Kantola M, Lötjönen S, Harri M, Nurminen L, Kaikkonen J, Nyyssönen K. 1998. Biological trace element research. 65: 197-210 A1 Journal article (refereed), original research
Complete spectral analysis of the 1H NMR 16-spin system of beta-pinene
Kolehmainen E, Laihia K, Laatikainen R, Vepsäläinen J, Niemitz M, Suontamo R. 1997. Magnetic resonance in chemistry. 35: 463-467 A1 Journal article (refereed), original research
Identification of a common structural motif in the disordered N-terminal region of bacterial flagellins Evidence for a new class of fibril-forming peptides
Hakalehto E, Santa H, Vepsäläinen J, Laatikainen R, Finne J. 1997. Febs journal. 250: 19-29 A1 Journal article (refereed), original research
A computational strategy for the deconvolution of NMR spectra with multiplet structures and constraints: analysis of overlapping 13C-2H multiplets of 13C enriched metabolites from cell suspensions incubated in deuterated media
Laatikainen R, Niemitz M, Malaisse WJ, Biesemans M, Willem R. 1996. Magnetic resonance in medicine. 36: 359-365 A1 Journal article (refereed), original research
General strategies for total-lineshape-type spectral analysis of NMR spectra using integral-transform iterator
Laatikainen R, Niemitz M, Weber U, Sundelin J, Hassinen T, Vepsäläinen J. 1996. JOURNAL OF MAGNETIC RESONANCE (A). 120: 1-10 A1 Journal article (refereed), original research
Reactions of hydrated formaldehyde in nasal mucus
Priha E, Liesivuori J, Santa H, Laatikainen R. 1996. Chemosphere. 32: 1077-1082 A1 Journal article (refereed), original research
NMR study of aromatic-aromatic interactions for benzene and some other fundamental aromatic systems using alignment of aromatics in strong magnetic field
Laatikainen R, Ratilainen J, Sebastian R, Santa H. 1995. Journal of the American Chemical Society. 117: 11006-11010 A1 Journal article (refereed), original research
A general route to 3-unsubstituted 1,5-diaryl-2,4-pentanediones and -4-methoxy-2-pentanones
Pulkkinen, Juha; Vepsäläinen, Jouko; Laatikainen, Reino. 1994. Tetrahedron letters. 35: 9749-9750 A1 Journal article (refereed), original research

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Reino Laatikainen

21Ne and 131Xe NMR study of electric field gradients and multinuclear NMR study of the composition of a ferroelectric liquid crystal

Biowaste Conversion into Carboxylate Platform Chemicals

Forest Industry Hygiene Control with Reference to Waste Refinement

Meat Industry Hygiene, Outlines of Safety and Material Recycling by Biotechnological Means

Quantitative quantum mechanical NMR analysis: the superior tool for analysis of biofluids

Some Remarks on Processing of Slaughterhouse Wastes from Ecological Chicken Abattoir and Farm

Using slaughterhouse waste in a biochemical-based biorefinery - results from pilot scale tests

Volatile fatty acids as an added value from biowaste

Comprehensive strategy for proton chemical shift prediction: linear prediction with nonlinear corrections

Preclinical pharmacology of FL442, a novel nonsteroidal androgen receptor modulator

Quantitative Quantum Mechanical Spectral Analysis (qQMSA) of (1)H NMR spectra of complex mixtures and biofluids

Discovery of 5-benzyl-3-phenyl-4,5-dihydroisoxazoles and 5-benzyl-3-phenyl-1,4,2-dioxazoles as potent firefly luciferase inhibitors

Firefly luciferase inhibitor-conjugated peptide quenches bioluminescence: a versatile tool for real time monitoring cellular uptake of biomolecules

MetIDB: a publicly accessible database of predicted and experimental 1H NMR spectra of flavonoids

Novel non-steroidal compounds as androgen receptor modulators

¹H-NMR fingerprinting of Vaccinium vitis-idaea flavonol glycosides

Combining NMR ensembles and molecular dynamics simulations provides more realistic models of protein structures in solution and leads to better chemical shift prediction

Design, synthesis and biological evaluation of nonsteroidal cycloalkane[d]isoxazole-containing androgen receptor modulators

High-throughput quantification of circulating metabolites improves prediction of subclinical atherosclerosis

Metabolic Diversity of Progressive Kidney Disease in 325 Patients with Type 1 Diabetes (the FinnDiane Study)

Molecular dynamics simulations for human CAR inverse agonists

¹H NMR spectral analysis and conformational behavior of n-alkanes in different chemical environments

Computerized Analysis of High-resolution Solution-state Spectra

NMR protocol for determination of oxidation susceptibility of serum lipids and application of the protocol to a chocolate study

13C Isotope Effects on 1H Chemical Shifts: NMR Spectral Analysis of 13C-Labelled D-glucose and Some 13C-Labelled Amino Acids

Screening of binding activity of Streptococcus pneumoniae, Streptococcus agalactiae and Streptococcus suis to berries and juices

Sex hormones and their analogues in neuroimmune biology.

Synthesis and biological evaluation of phenolic 4,5-dihydroisoxazoles and 3-hydroxy ketones as estrogen receptor alpha and beta agonists

4D prediction of protein 1H chemical shifts

High-throughput serum NMR metabonomics for cost effect holistic studies on systematic metabolism

NMR and UPLC-qTOF-MS/MS characterisation of novel phenylethanol derivates of phenylpropanoid glucosides from the leaves of strawberry (Fragaria x ananassa cv. Jonsok)

NMR and UPLC-qTOF-MS/MS characterisation of novel phenylethanol derivatives of phenylpropanoid glucosides from the leaves of strawberry (Fragaria x ananassa cv. Jonsok)

Novel 4,5-dihydroisoxazoles with estrogenic activity

Novel beta-hydroxyketones and beta-alkoxyketones with estrogenic activity

Stilbene synthase gene transfer resulted in down regulation of endogenous chalcone synthase in strawberry (Fragaria x ananassa) and led to the identification of novel phenylpropanoid glucosides

A multi-metabolite analysis of serum by 1H NMR spectroscopy: Early systemic signs of Alzheimer's disease

Ligand specificity of constitutive androstane receptor as probed by induced-fit drocking and mutagenesis

Quantification of 1H NMR spectra of human cerebrospinal fluid: a protocol based on constrained total-line-shape analysis

Spectral analysis of 1H coupled 13C spectra of the amino acids: adaptive spectral library of amino acid 13C isotopomers and positional fractional 13C enrichments

Synthesis and evaluation of estrogen agonism of diaryl 4,5-dihydroisoxazoles, 3-hydroxyketones, 3-methoxyketones, and 1,3-diketones: A compound set forming a 4D molecular library

1H NMR at 800 MHz facilitates detailed phospholipid follow-up during atherogenic modifications in low density lipoproteins

1H NMR metabonomics of plasma lipoprotein subclasses: elucidation of metabolic clustering by self-organising maps

Complete 1H NMR spectral fingerprint of huperzine A

The inherent accuracy of 1H NMR spectroscopy to quantify plasma lipoproteins is subclass dependent

Beta-amyloid infusion results in delayed and age-dependent learning deficits without role of inflammation or beta-amyloid deposits

Improving the performance of SOMFA by use of standard multivariate methods

Strategies for organic impurity quantification by 1H NMR spectroscopy: constrained total-line-shape fitting

Application of novel metallocomplexes for mimicking of cytochrome P450 analysis of product distribution for 1-hexene as a substrate

Determination of the degree of substitution of acetylated starch by hydrolysis, 1H NMR and TGA/IR

Ligand intramolecular motions in ligand-protein interaction: ALPHA, a novel dynamic descriptor and a QSAR study with extended steroid benchmark dataset

FLUFF-BALL, a template-based grid-independent superposition and QSAR technique: validation using a benchmark steroid data set

Reduction of 6/7-substituted 3-phenyltrop-3-en-2-ones: stereoselectivity and conformational analysis of the products

Antioxidant and antitumor effects of hydroxymatairesinol (HM-3000, HMR), a lignan isolated from the knots of spruce

Correlative motions and memory effects in molecular dynamics simulations of molecules: principal components and rescaled range analysis suggest that the motions of native BPTI are more correlated than those of its mutants

Evaluation of a novel electronic eigenvalue (EEVA) molecular descriptor for QSAR/QSPR studies: Validation using a benchmark steroid data set

Isolation and identification of Aspergillus fumigatus mycotoxins on growth medium and some building materials

Stability and amino acid preferences of type VIII reverse turn: the most common turn in peptides?

Synthesis and antimicrobial activity of the symmetric dimeric form of tetmporin a based on 3-N,N-di(3-aminopropyl)amino propanoic acid as the branching unit

A proton relay process as the mechanism of activation of the histamine H3-receptor determined by 1H NMR and ab initio quantum mechanical calculations

Conformational flexibility and role of aromatic-aromatic interactions in the crystal packing of the coordination compounds of some novel quadridentate Schiff bases

Effect of supplementation with organic selenium on mercury status as measured by mercury in pubic hair

Oligonucleotides containing 9-(2-deoxy-2-fluoro-beta-d-arabinofuranosyl)-adenine and -guanine: synthesis, hybridization and antisense properties

1H NMR study on putative intramolecular hydrogen bonding for histamine H3-receptor agonists

Characterization of a conformationally flexible system: NMR spectroscopic study of 1,5-diphenylpentane-2,4-dione

Folding of alfarbeta and ethabeta reverse turns: a nanosecond molecular dynamics simulation of the hexapeptide MSALNT and octapeptide NMSALNTL in water

Nuclear magnetic resonance and molecular orbital study of some cocaine analogues

Solvent dependence of rotational energetics and formyl-proton long-range spin-spin coupling behavior of 2,6-dichloro- and 2,6-dinitrobenzaldehydes using dipolar couplings and temperature dependence of long-range couplings

A bovine dander allergen, comparative modeling, and similarities and differences in folding with related proteins

Internal motions of native lysozyme are more organized than those of mutants: a principal component analysis of molecular dynamics data

Mercury-binding capacity of organic and inorganic selenium in rat blood and liver

Complete spectral analysis of the 1H NMR 16-spin system of beta-pinene

Identification of a common structural motif in the disordered N-terminal region of bacterial flagellins Evidence for a new class of fibril-forming peptides

A computational strategy for the deconvolution of NMR spectra with multiplet structures and constraints: analysis of overlapping 13C-2H multiplets of 13C enriched metabolites from cell suspensions incubated in deuterated media

General strategies for total-lineshape-type spectral analysis of NMR spectra using integral-transform iterator

Reactions of hydrated formaldehyde in nasal mucus

NMR study of aromatic-aromatic interactions for benzene and some other fundamental aromatic systems using alignment of aromatics in strong magnetic field

A general route to 3-unsubstituted 1,5-diaryl-2,4-pentanediones and -4-methoxy-2-pentanones