Eveliina Korhonen

Inflammasome activation in response to aberrations of cellular homeostasis in epithelial cells from human cornea and retina

Korhonen, Eveliina. 2024. Acta ophthalmologica. 102: 3-68 B1 Non-refereed journal articles

Cis-urocanic acid improves cell viability and suppresses inflammasome activation in human retinal pigment epithelial cells

Korhonen, Eveliina; Piippo, Niina; Hytti, Maria; Kaarniranta, Kai; Kauppinen, Anu. 2023. Biochemical pharmacology. 216: A1 Journal article (refereed), original research

Inflammasome activation in response to aberrations of cellular homeostasis in epithelial cells from human cornea and retina

Korhonen, Eveliina. 2023. Publications of the University of Eastern Finland. Dissertations in Health Sciences G5 Doctoral dissertation (article)

The Prolyl Oligopeptidase Inhibitor KYP-2047 Is Cytoprotective and Anti-Inflammatory in Human Retinal Pigment Epithelial Cells with Defective Proteasomal Clearance

Toppila, Maija; Hytti, Maria; Korhonen, Eveliina; Ranta-aho, Sofia; Harju, Niina; Forsberg, Markus M.; Kaarniranta, Kai; Jalkanen, Aaro; Kauppinen, Anu. 2023. Antioxidants. 12: A1 Journal article (refereed), original research

Antimycin A-induced mitochondrial dysfunction regulates inflammasome signaling in human retinal pigment epithelial cells

Korhonen, Eveliina; Hytti, Maria; Piippo, Niina; Kaarniranta, Kai; Kauppinen, Anu. 2021. Experimental eye research. 209: 108687 A1 Journal article (refereed), original research

Differential Expression of Inflammasome-Related Genes in Induced Pluripotent Stem-Cell-Derived Retinal Pigment Epithelial Cells with or without History of Age-Related Macular Degeneration

Hytti, Maria; Korhonen, Eveliina; Hongisto, Heidi; Kaarniranta, Kai; Skottman, Heli; Kauppinen, Anu. 2021. International journal of molecular sciences. 22: 6800 A1 Journal article (refereed), original research

Hydroquinone Induces NLRP3-Independent IL-18 Release from ARPE-19 Cells

Bhattarai, Niina; Korhonen, Eveliina; Mysore, Yashavanthi; Kaarniranta, Kai; Kauppinen, Anu. 2021. Cells. 10: 1405 A1 Journal article (refereed), original research

TAS-116, a Well-Tolerated Hsp90 Inhibitor, Prevents the Activation of the NLRP3 Inflammasome in Human Retinal Pigment Epithelial Cells

Ranta-aho, Sofia; Piippo, Niina; Korhonen, Eveliina; Kaarniranta, Kai; Hytti, Maria; Kauppinen, Anu. 2021. International journal of molecular sciences. 22: 4875 A1 Journal article (refereed), original research

Only IL-1ß release is inflammasome-dependent upon ultraviolet B irradiation although IL-18 is also secreted

Korhonen, Eveliina; Piippo, Niina; Hytti, Maria; Hyttinen, Juha; Kaarniranta, Kai; Kauppinen, Anu. 2020. Faseb journal. 34: 6437-6448 A1 Journal article (refereed), original research

Resvega Alleviates Hydroquinone-Induced Oxidative Stress in ARPE-19 Cells

Bhattarai, Niina; Korhonen, Eveliina; Toppila, Maija; Koskela, Ali; Kaarniranta, Kai; Mysore, Yashavanthi; Kauppinen, Anu. 2020. International journal of molecular sciences. 21: 2066 A1 Journal article (refereed), original research

UV-B-Induced Inflammasome Activation Can Be Prevented by Cis-Urocanic Acid in Human Corneal Epithelial Cells

Korhonen, Eveliina; Bisevac, Jovana; Hyttinen, Juha MT; Piippo, Niina; Hytti, Maria; Kaarniranta, Kai; Petrovski, Goran; Kauppinen, Anu. 2020. Investigative ophthalmology and visual science. 61: 7 A1 Journal article (refereed), original research

Antimycin A-Induced Mitochondrial Damage Causes Human RPE Cell Death despite Activation of Autophagy

Hytti, Maria; Korhonen, Eveliina; Hyttinen, Juha M T; Roehrich, Heidi; Kaarniranta, Kai; Ferrington, Deborah A; Kauppinen, Anu. 2019. Oxidative medicine and cellular longevity. 2019: 1583656 A1 Journal article (refereed), original research

Resvega alleviates oxidative stress and inflammasome activation in retinal pigment epithelial cells

Bhattarai, Niina; Korhonen, Eveliina; Toppila, Maija; Kaarniranta, Kai; Kauppinen, Anu. 2019. Acta ophthalmologica

SQSTM1/p62 regulates the production of IL-8 and MCP-1 in IL-1ß-stimulated human retinal pigment epithelial cells

Korhonen, E; Piippo, N; Hytti, M; Hyttinen, JMT; Kaarniranta, K; Kauppinen, A. 2019. Cytokine. 116: 70-77 A1 Journal article (refereed), original research

Autophagy Stimulus Promotes Early HuR Protein Activation and p62/SQSTM1 Protein Synthesis in ARPE-19 Cells by Triggering Erk1/2, p38MAPK, and JNK Kinase Pathways

Marchesi, Nicoletta; Thongon, Natthakan; Pascale, Alessia; Provenzani, Alessandro; Koskela, Ali; Korhonen, Eveliina; Smedowski, Adrian; Govoni, Stefano; Kauppinen, Anu; Kaarniranta, Kai; Amadio, Marialaura. 2018. Oxidative medicine and cellular longevity. 2018: 4956080 A1 Journal article (refereed), original research

Hsp90 inhibition as a means to inhibit activation of the NLRP3 inflammasome

Piippo, N; Korhonen, E; Hytti, M; Skottman, H; Kinnunen, K; Josifovska, N; Petrovski, G; Kaarniranta, K; Kauppinen, A. 2018. Scientific reports. 8: 6720 A1 Journal article (refereed), original research

Oxidative Stress is the Principal Contributor to Inflammasome Activation in Retinal Pigment Epithelium Cells with Defunct Proteasomes and Autophagy

Piippo, Niina; Korhonen, Eveliina; Hytti, Maria; Kinnunen, Kati; Kaarniranta, Kai; Kauppinen, Anu. 2018. Cellular physiology and biochemistry. 49: 359-367 A1 Journal article (refereed), original research

CB2 receptor activation causes an ERK1/2-dependent inflammatory response in human RPE cells

Hytti M, Andjelic S, Josifovska N, Piippo N, Korhonen E, Hawlina M, Kaarniranta K, Nevalainen TJ, Petrovski G, Parkkari T, Kauppinen A. 2017. Scientific reports. 7: 16169 A1 Journal article (refereed), original research

Two dietary polyphenols, fisetin and luteolin, reduce inflammation but augment DNA damage-induced toxicity in human RPE cell

Hytti M, Szabó D, Piippo N, Korhonen E, Honkakoski P, Kaarniranta K, Petrovski G, Kauppinen A. 2017. Journal of nutritional biochemistry. 42: 37-42 A1 Journal article (refereed), original research

Inhibition of BET bromodomains alleviates inflammation in human RPE cells

Hytti Maria, Tokarz P, Määttä E, Piippo Niina, Korhonen Eveliina, Suuronen T, Honkakoski Paavo, Kaarniranta Kai, Lahtela-Kakkonen Maija, Kauppinen Anu. 2016. Biochemical pharmacology. 110-111: 71-79 A1 Journal article (refereed), original research

Long-term topical application of preservative-free prostaglandin analogues evokes macrophage infiltration in the ocular adnexa

Trzeciecka Anna, Paterno J Jussi, Toropainen Elisa, Koskela Ali, Podracka Lucia, Korhonen Eveliina, Kauppinen Anu, Kaarniranta Kai, Smedowski Adrian. 2016. European journal of pharmacology. 788: 12-20 A1 Journal article (refereed), original research

Cytotoxicity assessment of porous silicon microparticles for ocular drug delivery

Korhonen Eveliina, Rönkkö Seppo, Hillebrand Satu, Riikonen Joakim, Xu Wujun, Järvinen Kristiina, Lehto Vesa-Pekka, Kauppinen Anu. 2015. European journal of pharmaceutics and biopharmaceutics. 2016; 100: 1-8 A1 Journal article (refereed), original research

Fisetin and luteolin protect human retinal pigment epithelial cells from oxidative stress-induced cell death and regulate inflammation

Hytti Maria, Piippo Niina, Korhonen Eveliina, Honkakoski Paavo, Kaarniranta Kai, Kauppinen Anu. 2015. Scientific reports. 5: A1 Journal article (refereed), original research

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Inflammasome activation in response to aberrations of cellular homeostasis in epithelial cells from human cornea and retina

Cis-urocanic acid improves cell viability and suppresses inflammasome activation in human retinal pigment epithelial cells

Inflammasome activation in response to aberrations of cellular homeostasis in epithelial cells from human cornea and retina

The Prolyl Oligopeptidase Inhibitor KYP-2047 Is Cytoprotective and Anti-Inflammatory in Human Retinal Pigment Epithelial Cells with Defective Proteasomal Clearance

Antimycin A-induced mitochondrial dysfunction regulates inflammasome signaling in human retinal pigment epithelial cells

Differential Expression of Inflammasome-Related Genes in Induced Pluripotent Stem-Cell-Derived Retinal Pigment Epithelial Cells with or without History of Age-Related Macular Degeneration

Hydroquinone Induces NLRP3-Independent IL-18 Release from ARPE-19 Cells

TAS-116, a Well-Tolerated Hsp90 Inhibitor, Prevents the Activation of the NLRP3 Inflammasome in Human Retinal Pigment Epithelial Cells

Only IL-1ß release is inflammasome-dependent upon ultraviolet B irradiation although IL-18 is also secreted

Resvega Alleviates Hydroquinone-Induced Oxidative Stress in ARPE-19 Cells

UV-B-Induced Inflammasome Activation Can Be Prevented by Cis-Urocanic Acid in Human Corneal Epithelial Cells

Antimycin A-Induced Mitochondrial Damage Causes Human RPE Cell Death despite Activation of Autophagy

Resvega alleviates oxidative stress and inflammasome activation in retinal pigment epithelial cells

SQSTM1/p62 regulates the production of IL-8 and MCP-1 in IL-1ß-stimulated human retinal pigment epithelial cells

Autophagy Stimulus Promotes Early HuR Protein Activation and p62/SQSTM1 Protein Synthesis in ARPE-19 Cells by Triggering Erk1/2, p38MAPK, and JNK Kinase Pathways

Hsp90 inhibition as a means to inhibit activation of the NLRP3 inflammasome

Oxidative Stress is the Principal Contributor to Inflammasome Activation in Retinal Pigment Epithelium Cells with Defunct Proteasomes and Autophagy

CB2 receptor activation causes an ERK1/2-dependent inflammatory response in human RPE cells

Two dietary polyphenols, fisetin and luteolin, reduce inflammation but augment DNA damage-induced toxicity in human RPE cell

Inhibition of BET bromodomains alleviates inflammation in human RPE cells

Long-term topical application of preservative-free prostaglandin analogues evokes macrophage infiltration in the ocular adnexa

Cytotoxicity assessment of porous silicon microparticles for ocular drug delivery

Fisetin and luteolin protect human retinal pigment epithelial cells from oxidative stress-induced cell death and regulate inflammation