Katja Sirviö (ent./former Puttonen)

Metabolic alterations in Parkinson's disease astrocytes

Sonninen, Tuuli-Maria; Hämäläinen, Riikka H; Koskuvi, Marja; Oksanen, Minna; Shakirzyanova, Anastasia; Wojciechowski, Sara; Puttonen, Katja; Naumenko, Nikolay; Goldsteins, Gundars; Laham-Karam, Nihay; Lehtonen, Marko; Tavi, Pasi; Koistinaho, Jari; Lehtonen, ¦árka. 2020. Scientific reports. 10: 14474 A1 Journal article (refereed), original research

PSEN1 Mutant iPSC-Derived Model Reveals Severe Astrocyte Pathology in Alzheimer's Disease

Oksanen M, Petersen AJ, Naumenko N, Puttonen K, Lehtonen ¦, Gubert Olivé M, Shakirzyanova A, Leskelä S, Sarajärvi T, Viitanen M, Rinne JO, Hiltunen M, Haapasalo A, Giniatullin R, Tavi P, Zhang SC, Kanninen KM, Hämäläinen RH, Koistinaho J. 2017. Stem cell reports. 9: 1885-1897 A1 Journal article (refereed), original research

Creation of a library of induced pluripotent stem cells from Parkinsonian patients

Holmqvist S, Lehtonen S, Chumarina M, Puttonen KA, Azevedo C, Lebedeva O, Ruponen M, Oksanen M, Djelloul M, Collin A, Goldwurm S, Meyer M, Lagarkova M, Kiselev S, Koistinaho J, Roybon L. 2016. npj parkinson's disease. : 16009 A1 Journal article (refereed), original research

Dancing with the Bosses: Creative Movement as a Method

Hujala Anneli, Laulainen Sanna, Kinni Riitta-Liisa, Kokkonen Kaija, Puttonen Katja, Aunola Anniina. 2015. Organizational aesthetics. 5: 11-36 A1 Journal article (refereed), original research

Generation of Functional Neuromuscular Junctions from Human Pluripotent Stem Cell Lines

Puttonen Katja A, Ruponen Marika, Naumenko Nikolay, Hovatta Outi H, Tavi Pasi, Koistinaho Jari. 2015. Frontiers in cellular neuroscience. 9:473: - A1 Journal article (refereed), original research

Immunomodulation by interleukin-33 is protective in stroke through modulation of inflammation

Korhonen Paula, Kanninen Katja M, Lehtonen Sarka, Lemarchant Sighild, Puttonen Katja A, Oksanen Minna, Dhungana Hiramani, Loppi Sanna, Pollari Eveliina, Wojciechowski Sara, Kidin Iurii, Garcia-Berrocoso Teresa, Giralt Dolors, Montaner Joan, Koistinaho Jan I, Malm Tarja. 2015. Brain behavior and immunity. 49: 322-336 A1 Journal article (refereed), original research

Transplanted human iPSC-derived neural progenitor cells do not promote functional recovery of pharmacologically immunosuppressed mice with contusion spinal cord injury

Pomeshchik Y, Puttonen KA, Kidin I, Ruponen M, Lehtonen S, Malm T, Akesson E, Hovatta O, Koistinaho J. 2014. Cell transplantation. 2014 Sep 8. [Epub ahead of print]: - - A1 Journal article (refereed), original research

Chondrogenic differentiation of human pluripotent stem cells in chondrocyte co-culture

Qu C, Puttonen KA, Lindeberg H, Ruponen M, Hovatta O, Koistinaho J, Lammi MJ. 2013. International journal of biochemistry and cell biology. : 1802-1812 A1 Journal article (refereed), original research

Improved method of producing human neural progenitor cells of high purity and in large quantities from pluripotent stem cells for transplantation studies

Puttonen Katja A, Ruponen Marika, Kauppinen Riitta, Wojciechowski Sara, Hovatta Outi, Koistinaho Jari. 2012. Cell transplantation. 2013:22: 1753-1766 A1 Journal article (refereed), original research

Minocycline protects SH-SY5Y cells from 6-hydroxydopamine by inhibiting both caspase-dependent and -independent programmed cell death

Ossola Bernardino, Lantto Tiina A, Puttonen Katja A, Tuominen Raimo K, Raasmaja Atso, Männistö Pekka T. 2012. Journal of neuroscience research. 90: 682-690 A1 Journal article (refereed), original research

Prolyl endopeptidase is involved in cellular signalling in human neuroblastoma SH-SY5Y cells

Moreno-Baylach José, Puttonen Katja, Tenorio-Laranga Jofre, Venäläinen Jarkko, Storvik Markus, Forsberg Markus, García-Horsman Arturo. 2011. Neurosignals. 19: 97 - 109 A1 Journal article (refereed), original research

Different effects of scopolamine and inhibition of prolyl oligopeptidase on mnemonic and motility functions of young and 8- to 9-month-old rats in the radial-arm maze

Peltonen I, Jalkanen AJ, Sinervä V, Puttonen KA & Männistö P. 2010. Basic and clinical pharmacology and toxicology. 106: 280-287 A1 Journal article (refereed), original research

Induction of PUMA-alpha and down-regulation of PUMA-beta expression is associated with benzo(alpha)pyrene-induced apoptosis in MCF-7 cells

Tampio M, Markkanen P, Puttonen KA, Hagelberg E, Heikkinen H, Huhtinen K, Loikkanen J, Hirvonen M-R, Vähäkangas KH. 2009. Toxicology letters. 188: 214-222 A1 Journal article (refereed), original research

Different viabilities and toxicity types after 6-OHDA and Ara-C exposure evaluated by four assaays in five cell lines

Puttonen KA, Lehtonen S, Lampela P, Männistö PT, Raasmaja A. 2008. Toxicology in vitro. 22: 182-189 A1 Journal article (refereed), original research

Beneficial effect of prolyl oligopeptidase inhibition on spatial memory in young but not in old scopolamine-treated rats

Jalkanen AJ, Puttonen KA, Venäläinen JI, Sinervä V, Mannila A, Ruotsalainen S, Jarho EM, Wallén EAA, Männistö PT. 2007. Basic and clinical pharmacology and toxicology. 100: 132-138 A1 Journal article (refereed), original research

A prolyl oligopeptidase inhibitor, Z-Pro-Prolinal, inhibits glyceraldehyde-3-phosphate dehydrogenase translocation and production of reactive oxygen species in CV1-P cells exposed to 6-hydroxydopamine

Puttonen KA, Lehtonen S, Raasmaja A, Männistö PT. 2006. Toxicology in vitro. 20: 1446-1454 A1 Journal article (refereed), original research

Effect of cell-surface glycosaminoglycans on cationic carrier combined with low-MW PEI-mediated gene transfection

Lampela P, Soininen P, Puttonen KA, Ruponen M, Urtti A, Männistö PT, Raasmaja A. 2004. International journal of pharmaceutics. 284: 43-52 A1 Journal article (refereed), original research

The roles of dopamine transporter and Bcl-2 protein in the protection of CV1-P cells from 6-OHDA-induced toxicity

Manakova S, Puttonen KA, Raasmaja A, Männistö PT. 2004. Toxicology letters. 154: 117-123 A1 Journal article (refereed), original research

Ara-C induces apoptosis in monkey fibroblast cells

Manakova S, Puttonen KA, Raasmaja A, Männistö PT. 2003. Toxicology in vitro. 17: 367-373 A1 Journal article (refereed), original research

Increased p53 levels without caspase-3 activity and change of cell viability in 6-hydroxydopamine-treated CV1-P cells

Puttonen KA, Manakova S, Raasmaja A, Männistö PT. 2003. Cell biology and toxicology. 19: 177-187 A1 Journal article (refereed), original research

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Katja A. Sirviö (ent./former Puttonen)

Publications

Metabolic alterations in Parkinson's disease astrocytes

PSEN1 Mutant iPSC-Derived Model Reveals Severe Astrocyte Pathology in Alzheimer's Disease

Creation of a library of induced pluripotent stem cells from Parkinsonian patients

Dancing with the Bosses: Creative Movement as a Method

Generation of Functional Neuromuscular Junctions from Human Pluripotent Stem Cell Lines

Immunomodulation by interleukin-33 is protective in stroke through modulation of inflammation

Transplanted human iPSC-derived neural progenitor cells do not promote functional recovery of pharmacologically immunosuppressed mice with contusion spinal cord injury

Chondrogenic differentiation of human pluripotent stem cells in chondrocyte co-culture

Improved method of producing human neural progenitor cells of high purity and in large quantities from pluripotent stem cells for transplantation studies

Minocycline protects SH-SY5Y cells from 6-hydroxydopamine by inhibiting both caspase-dependent and -independent programmed cell death

Prolyl endopeptidase is involved in cellular signalling in human neuroblastoma SH-SY5Y cells

Different effects of scopolamine and inhibition of prolyl oligopeptidase on mnemonic and motility functions of young and 8- to 9-month-old rats in the radial-arm maze

Induction of PUMA-alpha and down-regulation of PUMA-beta expression is associated with benzo(alpha)pyrene-induced apoptosis in MCF-7 cells

Different viabilities and toxicity types after 6-OHDA and Ara-C exposure evaluated by four assaays in five cell lines

Beneficial effect of prolyl oligopeptidase inhibition on spatial memory in young but not in old scopolamine-treated rats

A prolyl oligopeptidase inhibitor, Z-Pro-Prolinal, inhibits glyceraldehyde-3-phosphate dehydrogenase translocation and production of reactive oxygen species in CV1-P cells exposed to 6-hydroxydopamine

Effect of cell-surface glycosaminoglycans on cationic carrier combined with low-MW PEI-mediated gene transfection

The roles of dopamine transporter and Bcl-2 protein in the protection of CV1-P cells from 6-OHDA-induced toxicity

Ara-C induces apoptosis in monkey fibroblast cells

Increased p53 levels without caspase-3 activity and change of cell viability in 6-hydroxydopamine-treated CV1-P cells