Molecular Mechanisms Of Cardiometabolic Diseases

Cardiometabolic diseases are the most common cause of death worldwide. The main goal of our group is to identify novel molecular mechanisms of development of calcific aortic valve disease and to reveal the effects of maternal cardiometabolic diseases on placental molecular processes and metabolic...

Redox signaling (Anna-Liisa Levonen group)

Nrf2 is a transcription factor mainly involved in combating cellular stress caused by reactive oxygen and nitrogen species. However, Nrf2 is also involved in cancer and cardiometabolic diseases, making it an essential drug target.

Metabolic MR Imaging Group

01.09.2017 -
Our group is interested in the development of novel metabolic imaging using hyperpolarised MRI to gain a better understanding of potential biomarkers for metabolic diseases in brain and in other organs such as heart.

GenomMed

01.04.2018 - 31.03.2022
The Genetics and Mechanisms in Translational Medicine Doctoral programme (GenomMed) will train international experts in translational genomics aiming to solve health care -related questions in the fields of cardiovascular and metabolic diseases and neurosciences to create solutions and innovation...

Clinical Nutrition and Nutrition Therapy

Our research is based on randomized controlled dietary inervention studies examining the effects of nutrients, diet and lifestyle on metabolism and risk of non-communicable diseases. We concentrate on the health effects of the quality of dietary fat, dietary fiber and dietary patterns. Lately, we...

EDCMET

01.01.2019 - 31.12.2023
Metabolic effects of Endocrine Disrupting Chemicals: novel testing METhods and adverse outcome pathways

Nutrigenomics and molecular nutrition group

Nutrigenomics and non-communicable or chronic diseases: Nutrigenomics is an emerging science in nutrition that uses molecular tools to better understand the physiological responses obtained through a certain diet in individuals and population groups.

At the Institute of Public Hea...

Genetics of gene regulation in disease

Transcription factors regulate their target genes not only upon specific stimuli, but also through binding to specific DNA sequences. Genetic variation that occurs on those binding sequences may disturb target gene expression. It is also a potential source for the “missing variation” in polygenic...