The Immune System in Skin Cancers

The research project, constituting a part of the North-Savo Skin Cancer Program (NoSCaP), is aimed at enhancing secondary prevention of skin cancers through identification of patients at increased risk for skin cancers.

Professor Ilkka Harvima and Dr Hanna Siiskonen, Department of ...

Single Cell Genomics Core

Single cell genomics technologies are transforming our understanding of biology and disease. This technology can be applied across a breadth of research areas to provide detailed cellular maps of tissues, organoids, and cell-based models.

As a part of the national Biocenter Finlan...

AIVI Stem Cell Center

The stem cell core facility of Biocenter Kuopio is a comprehensive provider of human pluripotent stem cell services at A.I. Virtanen Institute, Kuopio campus of the University of Eastern Finland.
iPSC-derived, disease specific cells serve as models to study human development or pathophysio...

Tumor-stroma interaction - Pasonen-Seppänen group

01.09.2019 -
Tumor microenvironment (TME) has an active contribution to tumor development and cancer progression. This extremely complex system is composed of multiple cell types, such as fibroblasts and infiltrating immune cells, and structural extracellular matrix (ECM), which is mainly composed of hyaluron...

Redox signaling (Anna-Liisa Levonen group)

Nrf2 is a transcription factor mainly involved in combating cellular stress caused by reactive oxygen and nitrogen species. However, Nrf2 is also involved in cancer and cardiometabolic diseases, making it an essential drug target.

Human Brain Disease Modelling (Lehtonen lab)

Our research focuses on revealing the cellular and molecular mechanisms of neurological diseases, especially Parkinson`s disease (PD). We utilize patient-derived brain cells in novel human-based models, including 3D culture systems and midbrain organoids, to more accurately mimic the diseased bra...

Ocular Drug Delivery group (ODD)

The Ocular Drug Delivery (ODD) group develops advanced drug delivery methods for targeted and prolonged drug delivery to both the anterior and posterior segments of the eye. Furthermore, we use computational tools for drug development and preclinical-to-clinical translation to build a quantitativ...