Anam Hammid
Postdoctoral Researcher
Doctor of Philosophy, Ph.D. (Drug research) Post-doctoral researcher
School of Pharmacy, Faculty of Health Sciences
I am a molecular biologist with further training and expertise in the field of drug research. I have completed my Ph.D. degree in the field of ocular drug development. My Ph.D. thesis focused on the quantification and determination of activities of drug-metabolizing enzymes (DME) in major eye tissues of preclinical species and humans. The outcomes highlighted that there is a profound variation in enzyme expression levels and activities among ocular tissues. Moreover, variation among species further complicates the translation studies. My research findings will help in ocular drug development and aid in understanding the complications associated with drug pharmacokinetics.
During my Ph.D., I gained expertise in various skills and techniques including enzyme assay optimization (kinetics, activity, and inhibition), proteomics study design and analysis, proteins extraction, western blot, ocular tissues extraction, biological sample preparation/homogenization, LC/MS analysis, cell culturing, etc.,
Currently, I am working as a post-doctoral researcher in the field of targeted and global proteomics. Proteomics is an advanced, highly sensitive, and high throughput technique to profile and characterize the protein expression levels in biological fluids. I am working toward developing my skills and deepening my expertise in the field of proteomics. I am looking forward to being an independent ocular drug research and proteomics scientist.
Research groups
Publications
9/9 items-
A Standardized Protocol for Extraction and Homogenization of Ocular Tissues
Hammid, Anam. 2024. Bio-protocol. 14: 1-11 A1 Journal article (refereed), original research -
Ocular Drug-Metabolizing Enzymes: Focus on Esterases
Hammid, Anam; Honkakoski, Paavo. 2024. Drug metabolism reviews. [Epub ahead of print 19 June 2024]: 1-15 A2 Review article, Literature review, Systematic review -
Aldehyde oxidase 1 activity and protein expression in human, rabbit, and pig ocular tissues
Hammid, Anam; Fallon, John K; Vellonen, Kati Sisko; Lassila, Toni; Reinisalo, Mika; Urtti, Arto; Gonzalez, Francisco; Tolonen, Ari; Smith, Philip C; Honkakoski, Paavo. 2023. European journal of pharmaceutical sciences. 191: . 106603 A1 Journal article (refereed), original research -
Expression and activities of carboxylesterase and aldehyde oxidase in human, rabbit, and pig ocular tissues
Hammid, Anam. 2023. Publications of the University of Eastern Finland. Dissertations in Health Sciences G5 Doctoral dissertation (article) -
Mass spectrometry in ocular drug research
del Amo, Eva M.; Vellonen, Kati‐Sisko; Urtti, Arto; Terasaki, Tetsuya; Hammid, Anam; Honkakoski, Paavo; Auriola, Seppo. 2023. Mass spectrometry reviews. [First published: 02 August 2023]: 1-32 A2 Review article, Literature review, Systematic review -
My Story at UEF Pharmacy
Hammid, Anam. 2023. Publications of the University of Eastern Finland. General series. 44: 152-154 E1 Popularised article, newspaper article -
Activity and expression of carboxylesterases and arylacetamide deacetylase in human ocular tissues
Hammid, Anam; Fallon, John K; Lassila, Toni; Vieiro, Paula; Balla, Anusha; Gonzalez, Francisco; Urtti, Arto; Smith, Philip C; Tolonen, Ari; Honkakoski, Paavo. 2022. Drug metabolism and disposition. 50: 1483-1492 A1 Journal article (refereed), original research -
Ocular metabolism and distribution of drugs in the rabbit eye: Quantitative assessment after intracameral and intravitreal administrations
del Amo, Eva M.; Hammid, Anam; Tausch, Melanie; Toropainen, Elisa; Sadeghi, Amir; Valtari, Annika; Puranen, Jooseppi; Reinisalo, Mika; Ruponen, Marika; Urtti, Arto; Sauer, Achim; Honkakoski, Paavo. 2022. International journal of pharmaceutics. 613: A1 Journal article (refereed), original research -
Carboxylesterase Activities and Protein Expression in Rabbit and Pig Ocular Tissues
Hammid, Anam; Fallon, John K; Lassila, Toni; Salluce, Giulia; Smith, Philip C; Tolonen, Ari; Sauer, Achim; Urtti, Arto; Honkakoski, Paavo. 2021. Molecular pharmaceutics. 18: 1305-1316 A1 Journal article (refereed), original research