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Frontotemporal Lobar Degeneration and Early Onset Dementia´s Profile image

Frontotemporal Lobar Degeneration and Early Onset Dementia

Research group
01.01.2019 -
Institute of Clinical Medicine, School of Medicine, Faculty of Health Sciences

Leaders

  • Research group has a wide expertise in clinical research as well as molecular genetics in early onset dementias, especially in frontotemporal dementia (FTD). During the last years, the main focus has been in the C9orf72 repeat expansion-associated FTD.

We aim to identify and characterize novel diagnostic tools, imaging methods (including functional MRI), biomarkers and etiological factors as well as the underlying pathogenesis of FTD and other early onset neurodegenerative disorders.

Our research focuses also on psychiatric manifestations of the behavioral variant of frontotemporal dementia (bvFTD) and cognitive decline in psychiatric disorders.

Our major research areas are:

  • Psychiatric manifestations in frontotemporal dementia
  • Role and etiology of cognitive decline in psychiatric disorders
  • Imaging and biomarkers in diagnostics and predicting the clinical course of frontotemporal lobar degeneration
  • Genetics of frontotemporal dementia and other early onset dementias

We are partner in

  • FinFTD reserach network
  • SynaDeg JPND EU-funded project
  • GENFI ( Genetic FTD Initiative, www.genfi.org)
  • FPI (FTD prevention Initiative, www.thefpi.org)
  • NIC-FTD (Neuropyschiatric International Consortium on Frontotemporal Dementia (https://www.alzheimercentrum.nl/wetenschap/lopend-onderzoek/nic-ftd/#1470052967796-59f78775-9a7f)
  • FRONTIERS (FRONTotemporal dementia Incidence European Research Network)

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