Animal Physiology
Leaders
Animals are exposed to natural and anthropogenic environmental stresses that affect animal life at all levels of biological organization, from molecules and cells to organs, individuals, and populations. We study the physiological adaptation and acclimation of ectothermal animals, mainly fish, and their adaptation to abiotic environmental conditions in the northern and arctic regions. In particular, the effects of temperature and oxygen availability on the cardiovascular function of fish under seasonally changing conditions are investigated. Our research topics include thermal adaptation and acclimation of fishes, the use of zebrafish as an animal model in thermal biology of ectotherms and human cardiac electrophysiology, and combined effects of thermal stress and environmental toxicants on fish cardiovascular function.
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Leaders
Professors
Senior Researchers
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Jaakko Haverinen
Visiting ResearcherDepartment of Environmental and Biological Sciences, Faculty of Science, Forestry and Technology -
Vesa Paajanen
University LecturerDepartment of Environmental and Biological Sciences, Faculty of Science, Forestry and Technology
Post-doctoral Researchers
Doctoral Researchers
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Publications
7 items-
Cardiac Toxicity of Cadmium Involves Complex Interaction Between Multiple Ion Currents in Rainbow Trout (Oncorhynchus mykiss) Ventricular Myocytes
Haverinen, Jaakko; Badr, Ahmed; Vornanen, Matti. 2021. Environmental toxicology and chemistry. 40: 2874-2885 A1 Journal article (refereed), original research -
Effects of Na+ channel isoforms and cellular environment on temperature tolerance of cardiac Na+ current in zebrafish (Danio rerio) and rainbow trout (Oncorhynchus mykiss)
Haverinen, Jaakko; Dzhumaniiazova, Irina; Abramochkin, Denis V.; Hassinen, Minna; Vornanen, Matti. 2021. Journal of experimental biology. 224: jeb241067 A1 Journal article (refereed), original research -
Ionic basis of atrioventricular conduction: ion channel expression and sarcolemmal ion currents of the atrioventricular canal of the rainbow trout (Oncorhynchus mykiss) heart
Hassinen, Minna; Dzhumaniiazova, Irina; Abramochkin, Denis V.; Vornanen, Matti. 2021. Journal of comparative physiology B : biochemical, systemic, and environmental physiology. 191: 327-346 A1 Journal article (refereed), original research -
Reduced ventricular excitability causes atrioventricular block and depression of heart rate in fish at critically high temperatures
Haverinen, Jaakko; Vornanen, Matti. 2020. Journal of experimental biology. 223: jeb225227 A1 Journal article (refereed), original research -
Polycyclic aromatic hydrocarbons phenanthrene and retene modify the action potential via multiple ion currents in rainbow trout Oncorhynchus mykiss cardiac myocytes
Vehniäinen, Eeva-Riikka; Haverinen, Jaakko; Vornanen, Matti. 2019. Environmental toxicology and chemistry. 38: 2145-2153 A1 Journal article (refereed), original research -
Cardiac voltage-gated sodium channel expression and electrophysiological characterization of the sodium current in the zebrafish (Danio rerio) ventricle
Haverinen, Jaakko; Hassinen, Minna; Korajoki, Hanna; Vornanen, Matti. 2018. Progress in biophysics and molecular biology. 138: 59-68 A1 Journal article (refereed), original research -
Zebrafish heart as a model for human cardiac electrophysiology
Vornanen Matti, Hassinen Minna. 2015. Channels. [Epub ahead of print 15 Dec 2015]: - A2 Review article, Literature review, Systematic review