Nutrigenomics and molecular nutrition group

Nutrigenomics and non-communicable or chronic diseases: Nutrigenomics is an emerging science in nutrition that uses molecular tools to better understand the physiological responses obtained through a certain diet in individuals and population groups.

At the Institute of Public Health and Clinical Nutrition, the main research interests of the nutrigenomics research line are:

• To study the relationship of lifestyles, including dietary changes, weight loss and physical activity, with the responses at the molecular and metabolic levels
that comprise omics areas such as metabolomics, transcriptomics and epigenomics in metabolic and cardiovascular diseases.
• Translate the above to specific dietary modifications and related biomarkers to study their metabolic response according to the genetic profile.
• Currently, a special interest is to study the molecular interactions between metabolites produced by the gut microbiota derived from specific dietary
nutrients that protect from type 2 diabetes and non-alcoholic fatty liver disease.

Recent projects:

• Molecular and metabolic mechanisms for the role of gut microbiota-derived indole propionic acid (IPA) in the prevention of type 2 diabetes
• Tailored diets for individuals with different fatty acid desaturase gene locus genotypes: FADSDIET2

Other projects:

• Studying the gene-pathway associations for IPA both for adipose and liver tissues.

PhD student
Ratika Sehgal, Ratika.Sehgal@uef.fi

Post Doc researcher
Mariana Ilha, Mariana.Ilha@uef.fi
Marjo Tuomainen, Marjo.Tuomainen@uef.fi

Group members - UEF

COLLABORATION - UEF

Cooperation partners

Publications by the research group members