Aleksi Leikas
Postdoctoral Researcher
A.I. Virtanen Institute for Molecular Sciences, Faculty of Health Sciences
aleksi.leikas@uef.fi
Research groups
Publications
6/6 items-
Clinical development and proof of principle testing of new regenerative vascular endothelial growth factor-D therapy for refractory angina: rationale and design of the phase 2 ReGenHeart trial
Leikas, Aleksi J; Hartikainen, Juha EK; Kastrup, Jens; Mathur, Anthony; Gyöngyösi, Mariann; Fernández-Avilés, Francisco; Sanz-Ruiz, Ricardo; Wojakowski, Wojtek; Gwizdała, Adrian; Luite, Riho; Nikkinen, Marko; Qayyum, Abbas A; Haack-Sørensen, Mandana; Kelham, Matthew; Jones, Daniel A; Hamzaraj, Kevin; Spannbauer, Andreas; Fernández-Santos, Maria E; Jędrzejek, Marek; Skoczyńska, Agnieszka; Vartiainen, Niklas; Knuuti, Juhani; Saraste, Antti; Ylä-Herttuala, Seppo. 2024. Open heart. 11: A1 Journal article (refereed), original research -
Adenoviral Gene Therapy Vectors in Clinical Use—Basic Aspects with a Special Reference to Replication-Competent Adenovirus Formation and Its Impact on Clinical Safety
Leikas, Aleksi J; Ylä-Herttuala, Seppo; Hartikainen, Juha E K. 2023. International journal of molecular sciences. 24: A2 Review article, Literature review, Systematic review -
Gene Therapy for Refractory Angina : Preclinical and Clinical Studies
Leikas, Aleksi. 2022. Publications of the University of Eastern Finland. Dissertations in Health Sciences G5 Doctoral dissertation (article) -
Intramyocardial adenoviral vascular endothelial growth factor‐D∆N∆C gene therapy does not induce ventricular arrhythmias
Leikas, Aleksi J; Hassinen, Iiro; Kivelä, Antti; Hedman, Antti; Mussalo, Hanna; Ylä‐Herttuala, Seppo; Hartikainen, Juha EK. 2022. Journal of gene medicine. 24: . e3437 A1 Journal article (refereed), original research -
Efficacy and Safety of Clinical Grade hVEGF-D [delta]N[delta]C Gene Therapy Containing Residual Replication-Competent Adenoviruses
Leikas, Aleksi Johannes; Laham-Karam, Nihay; Agtereek, Eline; Peltonen, Hanna Marjaana; Selander, Tuomas; Korpisalo, Petra; Holappa, Lari; Hartikainen, Juha EK; Heikura, Tommi; Ylä-Herttuala, Seppo. 2021. Human gene therapy. 32: 761-770 A1 Journal article (refereed), original research -
Long-term safety and efficacy of intramyocardial adenovirusmediated VEGF-DΔNΔC gene therapy eight-year follow-up of phase I KAT301 study
Leikas, Aleksi J.; Hassinen, Iiro; Hedman, Antti; Kivelä, Antti; Ylä-Herttuala, Seppo; Hartikainen, Juha E. K.. 2021. Gene therapy. Published online: 01 October 2021: 1 - 5 A1 Journal article (refereed), original research