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People
Alina Solomon

Alina Solomon

Professor

Institute of Clinical Medicine, School of Medicine, Faculty of Health Sciences

alina.solomon@uef.fi | +358 40 355 2015

Information Publications

Research groups

Brain Research Unit (BRU) - Clinical Trial Unit 01.01.2022 -
Clinical Alzheimer Research 01.01.2022 -
UEF - Nordic-UK Brain Network (UEF-NBN) 01.01.2022 -

Projects

CAIDE - Cardiovascular Risk Factors, Aging and Dementia Finished 01.01.1998 - 31.12.2022
e-FINGERS virtual facilitator for personalized brain health promotion and dementia prevention Finished 01.06.2022 - 31.03.2023
Neuro-Innovation 01.05.2021 - 30.04.2026

Publications

130/130 items

Alzheimer's disease genetic risk score and neuroimaging in the FINGER lifestyle trial
Saadmaan, Gazi; Dalmasso, Maria Carolina; Ramirez, Alfredo; Hiltunen, Mikko; Kemppainen, Nina; Lehtisalo, Jenni; Mangialasche, Francesca; Ngandu, Tiia; Rinne, Juha; Soininen, Hilkka; Stephen, Ruth; Kivipelto, Miia; Solomon, Alina. 2024. Alzheimer's & dementia. [Epub ahead of print 22 April 2024]: 1-6
Association of tooth location, occlusal support and chewing ability with cognitive decline and incident dementia
Asher, Sam; Suominen, Anna Liisa; Stephen, Ruth; Ngandu, Tiia; Koskinen, Seppo; Solomon, Alina. 2024. Journal of clinical periodontology. [Epub ahead of print 11 March 2024]: 1-16
Cognitive reserve, cortisol, and Alzheimer's disease biomarkers: A memory clinic study
Yerramalla, Manasa Shanta; Darin‐Mattsson, Alexander; Udeh‐Momoh, Chinedu T; Holleman, Jasper; Kåreholt, Ingemar; Aspö, Malin; Hagman, Göran; Kivipelto, Miia; Solomon, Alina; Marseglia, Anna; Sindi, Shireen. 2024. Alzheimer's & dementia. 20: 4486-4498
Diurnal cortisol, neuroinflammation, and neuroimaging visual rating scales in memory clinic patients
Holleman, Jasper; Daniilidou, Makrina; Kåreholt, Ingemar; Aspö, Malin; Hagman, Göran; Udeh-Momoh, Chinedu T; Spulber, Gabriela; Kivipelto, Miia; Solomon, Alina; Matton, Anna; Sindi, Shireen. 2024. Brain behavior and immunity. 118: 499-509
Diverging medical and legal perceptions of the need for legal guardianship in people with dementia: A qualitative study
Näkki, Kaisa; Mäki‐Petäjä‐Leinonen, Anna; Ervasti, Kaijus; Halkoaho, Arja; Nurmi, Sanna‐Maria; Solomon, Alina; Suhonen, Noora‐Maria; Portaankorva, Anne M.; Krüger, Johanna; Solje, Eino. 2024. European journal of neurology. 31:
Evaluation of Clinical Meaningfulness of Fortasyn Connect in Terms of “Time Saved”
Dickson, Samuel; Solomon, A; Kivipelto, M; Hartmann, T; van Hees, AMJ; Brownlee, A; Haaland, B; Mallinckrodt, CH; Hendrix, SB. 2024. The Journal of prevention of Alzheimer's disease. [Published: 13 March 2024]: 1-6
Machine learning prediction of future amyloid beta positivity in amyloid-negative individuals
Moradi, Elaheh; Prakash, Mithilesh; Hall, Anette; Solomon, Alina; Strange, Bryan; Tohka, Jussi; Alzheimer’s Disease Neuroimaging Initiative. 2024. Alzheimer's research and therapy. 16: . 46
Nutrition guidance within a multimodal intervention improves diet quality in prodromal Alzheimer’s disease: Multimodal Preventive Trial for Alzheimer’s Disease (MIND-ADmini)
Levak, Nicholas; Lehtisalo, Jenni; Thunborg, Charlotta; Westman, Eric; Andersen, Pia; Andrieu, Sandrine; Broersen, Laus M.; Coley, Nicola; Hartmann, Tobias; Irving, Gerd Faxén; Mangialasche, Francesca; Ngandu, Tiia; Pantel, Johannes; Rosenberg, Anna; Sindi, Shireen; Soininen, Hilkka; Solomon, Alina; Wang, Rui; Kivipelto, Miia. 2024. Alzheimer's research and therapy. 16: . 147
Sleep disturbances and change in multiple cognitive domains among older adults: A multicentre study of five Nordic cohorts
Overton, Marieclaire; Skoog, Johan; Laukka, Erika J; Bodin, Timothy Hadarsson; Darin Mattsson, Alexander; Sjöberg, Linnea; Hofer, Scott M; Johansson, Lena; Kulmala, Jenni; Kivipelto, Miia; Solomon, Alina; Skoog, Ingmar; Kåreholt, Ingemar; Sindi, Shireen. 2024. Sleep. 47: 1-17
Validation, Deployment, and Real-World Implementation of a Modular Toolbox for Alzheimer’s Disease Detection and Dementia Risk Reduction: The AD-RIDDLE Project
Malzbender, K.; Barbarino, P.; Ferrell, P. Barkman; Bradshaw, A.; Brookes, A. J.; Díaz, C.; van der Flier, W. M.; Georges, J.; Hansson, O.; Hartmanis, M.; Jönsson, L.; Krishnan, R.; MacLeod, T.; Mangialasche, F.; Mecocci, P.; Minguillon, C.; Middleton, L.; Pla, S.; Sardi, S. P.; Schöll, M.; Suárez-Calvet, M.; Weidner, W.; Visser, P. J.; Zetterberg, H.; Bose, N.; Solomon, A.; Kivipelto, Miia; AD-RIDDLE Consortium. 2024. The Journal of prevention of Alzheimer's disease. 11: 329-338
27‐hydroxycholesterol promotes oligodendrocyte maturation: Implications for hypercholesterolemia‐associated brain white matter changes
Alanko, Vilma; Gaminde‐Blasco, Adhara; Quintela‐López, Tania; Loera‐Valencia, Raúl; Solomon, Alina; Björkhem, Ingemar; Cedazo‐Minguez, Angel; Maioli, Silvia; Tabacaru, Graziella; Latorre‐Leal, María; Matute, Carlos; Kivipelto, Miia; Alberdi, Elena; Sandebring‐Matton, Anna. 2023. Glia. 71: 1414-1428
Association between Longitudinal Cerebrospinal Fluid Alzheimer's Biomarkers and the Lifestyle for Brain Health (LIBRA) Index: Findings from the European Prevention of Alzheimer's Dementia Cohort Study (EPAD LCS)
Saunders, Tyler S; Protsiv, M; Jenkins, N D; Solomon, A; Blennow, K; Ritchie, C; Muniz-Terrera, G. 2023. The Journal of prevention of Alzheimer's disease. 10: 542-550
Association of tooth count with cognitive decline and dementia in the Finnish adult population
Asher, Sam; Suominen, Anna Liisa; Stephen, Ruth; Ngandu, Tiia; Koskinen, Seppo; Solomon, Alina. 2023. Journal of clinical periodontology. 50: 1154-1166
Combined Evidence for a Long-Term, Clinical Slowing Effect of Multinutrient Intervention in Prodromal Alzheimer’s Disease: Post-Hoc Analysis of 3-Year Data from the LipiDiDiet Trial
Hendrix, Suzanne B; Soininen, H; Solomon, A; Visser, PJ; van Hees, AMJ; Counotte, DS; Nicodemus-Johnson, J; Dickson, SP; Blennow, K; Kivipelto, M; Hartmann, T; LipiDiDiet clinical study group. 2023. The Journal of prevention of Alzheimer's disease. 10: 464-470
Dementia prevention in memory clinics: recommendations from the European task force for brain health services
Frisoni, Giovanni B.; Altomare, Daniele; Ribaldi, Federica; Villain, Nicolas; Brayne, Carol; Mukadam, Naaheed; Abramowicz, Marc; Barkhof, Frederik; Berthier, Marcelo; Bieler-Aeschlimann, Melanie; Blennow, Kaj; Brioschi Guevara, Andrea; Carrera, Emmanuel; Chételat, Gaël; Csajka, Chantal; Demonet, Jean-François; Dodich, Alessandra; Garibotto, Valentina; Georges, Jean; Hurst, Samia; Jessen, Frank; Kivipelto, Miia; Llewellyn, David J.; McWhirter, Laura; Milne, Richard; Minguillón, Carolina; Miniussi. 2023. The Lancet regional health – Europe. 26:
Life-course stress, cognition, and diurnal cortisol in memory clinic patients without dementia
Holleman, Jasper; Kåreholt, Ingemar; Aspö, Malin; Hagman, Göran; Udeh-Momoh, Chinedu T; Kivipelto, Miia; Solomon, Alina; Sindi, Shireen. 2023. Archives of gerontology and geriatrics. 2024; 119:
Longitudinal study of Alzheimer's disease biomarkers, allostatic load, and cognition among memory clinic patients
Adedeji, Dickson O.; Holleman, Jasper; Juster, Robert-Paul; Udeh-Momoh, Chinedu T.; Kåreholt, Ingemar; Hagman, Göran; Aspö, Malin; Adagunodo, Sofia; Håkansson, Krister; Kivipelto, Miia; Solomon, Alina; Sindi, Shireen. 2023. Brain, behavior, & immunity : health. 28:
Multimodal Precision Prevention - A New Direction in Alzheimer’s Disease
Barbera, M; Perera, D; Matton, A; Mangialasche, F; Rosenberg, A; Middleton, L; Ngandu, T; Solomon, A; Kivipelto, Miia. 2023. The Journal of prevention of Alzheimer's disease. 10: 718-728
Precision medicine in neurodegeneration: the IHI-PROMINENT project
Tate, Ashley; Suárez-Calvet, Marc; Ekelund, Mats; Eriksson, Sven; Eriksdotter, Maria; Van Der Flier, Wiesje M.; Georges, Jean; Kivipelto, Miia; Kramberger, Milica G.; Lindgren, Peter; López, Juan Domingo Gispert; Lötjönen, Jyrki; Persson, Sofie; Pla, Sandra; Solomon, Alina; Thurfjell, Lennart; Wimo, Anders; Winblad, Bengt; Jönsson, Linus; PROMINENT consortium. 2023. Frontiers in neurology. 14: . 1175922
Response to “Comment on ‘Dementia prevention: The potential long-term cost-effectiveness of the FINGER prevention program’”
Wimo, Anders; Handels, Ron; Antikainen, Riitta; Eriksdotter, Maria; Jönsson, Linus; Knapp, Martin; Kulmala, Jenni; Laatikainen, Tiina; Lehtisalo, Jenni; Peltonen, Markku; Sköldunger, Anders; Soininen, Hilkka; Solomon, Alina; Timo Strandberg, T; Tuomilehto, Jaakko; Ngandu, Tiia; Kivipelto, Miia. 2023. Alzheimer's & dementia. 19: 4760-4763
Study design and methods: US study to protect brain health through lifestyle intervention to reduce risk (US POINTER)
Baker, Laura D; Snyder, Heather M; Espeland, Mark A; Whitmer, Rachel A; Kivipelto, Miia; Woolard, Nancy; Katula, Jeffrey; Papp, Kathryn V.; Ventrelle, Jennifer; Graef, Sarah; Hill, Marcus A; Rushing, Scott; Spell, Julia; Lovato, Laura; Felton, Deborah; Williams, Benjamin J; Ghadimi Nouran, Mina; Raman, Rema; Ngandu, Tiia; Solomon, Alina; Wilmoth, Sharon; Cleveland, Maryjo L; Williamson, Jeff D.; Lambert, Katherine L; Tomaszewski Farias, Sarah; Day, Claire E; Tangney, Christy C; Gitelman, Darren . 2023. Alzheimer's & dementia. 2024; 20: 769-782
Associations of Depressive Symptoms and Cognition in the FINGER Trial: A Secondary Analysis of a Randomised Clinical Trial
Neuvonen, Elisa; Lehtisalo, Jenni; Ngandu, Tiia; Levälahti, Esko; Antikainen, Riitta; Hänninen, Tuomo; Laatikainen, Tiina; Lindström, Jaana; Paajanen, Teemu; Soininen, Hilkka; Strandberg, Timo; Tuomilehto, Jaakko; Kivipelto, Miia; Solomon, Alina. 2022. Journal of clinical medicine. 11:
Cortisol, cognition and Alzheimer’s disease biomarkers among memory clinic patients
Holleman, Jasper; Adagunodo, Sofia; Kåreholt, Ingemar; Hagman, Göran; Aspö, Malin; Udeh-Momoh, Chinedu T; Solomon, Alina; Kivipelto, Miia; Sindi, Shireen. 2022. BMJ neurology open. 4:
Dementia Risk Scores and Their Role in the Implementation of Risk Reduction Guidelines
Anstey, Kaarin J; Zheng, Lidan; Peters, Ruth; Kootar, Scherazad; Barbera, Mariagnese; Stephen, Ruth; Dua, Tarun; Chowdhary, Neerja; Solomon, Alina; Kivipelto, Miia. 2022. Frontiers in neurology. 12: . 765454
Diabetes and Dementia: Spotlight on Multidomain Lifestyle Strategies
Hooshmand, Babak; Solomon, Alina. 2022. Neurology. 99: 927-928
Effect of a multi-domain lifestyle intervention on cardiovascular risk in older people: the FINGER trial
Lehtisalo, Jenni; Rusanen, Minna; Solomon, Alina; Antikainen, Riitta; Laatikainen, Tiina; Peltonen, Markku; Strandberg, Timo; Tuomilehto, Jaakko; Soininen, Hilkka; Kivipelto, Miia; Ngandu, Tiia. 2022. European heart journal. 43: 2054–2061
Metabolome-wide association study on ABCA7 indicates a role of ceramide metabolism in Alzheimer’s disease
Dehghan, Abbas; Pinto, Rui Climaco; Karaman, Ibrahim; Huang, Jian; Durainayagam, Brenan R.; Ghanbari, Mohsen; Nazeer, Areesha; Zhong, Qi; Liggi, Sonia; Whiley, Luke; Mustafa, Rima; Kivipelto, Miia; Solomon, Alina; Ngandu, Tiia; Kanekiyo, Takahisa; Aikawa, Tomonori; Radulescu, Carola I.; Barnes, Samuel J.; Graça, Gonçalo; Chekmeneva, Elena; Camuzeaux, Stephane; Lewis, Matthew R.; Kaluarachchi, Manuja R.; Ikram, M. Arfan; Holmes, Elaine; Tzoulaki, Ioanna; Matthews, Paul M.; Griffin, Julian L.; Ell. 2022. Proceedings of the National Academy of Sciences of the United States of America. 119: . e2206083119
Multimodal Preventive Trial for Alzheimer’s Disease: MIND-ADmini Pilot Trial Study Design and Progress
Sindi, S; Thunborg, C; Rosenberg, A; Andersen, P; Andrieu, S; Broersen, LM; Coley, N; Couderc, C; Duval, CZ; Faxen-Irving, G; Hagman, G; Hallikainen, M; Håkansson, K; Lehtisalo, J; Levak, N; Mangialasche, F; Pantel, J; Kekkonen, E; Rydström, A; Stigsdotter-Neely, A; Wimo, A; Ngandu, T; Soininen, H; Hartmann, T; Solomon, A; Kivipelto, M. 2022. The Journal of prevention of Alzheimer's disease. 9: 30-39
New insights into the genetic etiology of Alzheimer’s disease and related dementias
Bellenguez, Céline; Küçükali, Fahri; Jansen, Iris E.; Kleineidam, Luca; Moreno-Grau, Sonia; Amin, Najaf; Naj, Adam C.; Campos-Martin, Rafael; Grenier-Boley, Benjamin; Andrade, Victor; Holmans, Peter A.; Boland, Anne; Damotte, Vincent; van der Lee, Sven J.; Costa, Marcos R.; Kuulasmaa, Teemu; Yang, Qiong; de Rojas, Itziar; Bis, Joshua C.; Yaqub, Amber; Prokic, Ivana; Chapuis, Julien; Ahmad, Shahzad; Giedraitis, Vilmantas; Aarsland, Dag; Garcia-Gonzalez, Pablo; Abdelnour, Carla; Alarcón-Martín, Em. 2022. Nature genetics. 54: 412-436
Periodontal health, cognitive decline, and dementia: A systematic review and meta‐analysis of longitudinal studies
Asher, Sam; Stephen, Ruth; Mäntylä, Päivi; Suominen, Anna Liisa; Solomon, Alina. 2022. Journal of the american geriatrics society. 70: 2695-2709
Psychosocial determinants for adherence to a healthy lifestyle and intervention participation in the FINGER trial: an exploratory analysis of a randomised clinical trial
Neuvonen, Elisa; Lehtisalo, Jenni; Solomon, Alina; Antikainen, Riitta; Havulinna, Satu; Hänninen, Tuomo; Laatikainen, Tiina; Lindström, Jaana; Rautio, Nina; Soininen, Hilkka; Strandberg, Timo; Tuomilehto, Jaakko; Kivipelto, Miia; Ngandu, Tiia. 2022. Aging clinical and experimental research. 34: 1793-1805
Serum Thioredoxin-80 is associated with age, ApoE4, and neuropathological biomarkers in Alzheimer’s disease: a potential early sign of AD
Goikolea, Julen; Gerenu, Gorka; Daniilidou, Makrina; Mangialasche, Francesca; Mecocci, Patrizia; Ngandu, Tiia; Rinne, Juha; Solomon, Alina; Kivipelto, Miia; Cedazo-Minguez, Angel; Sandebring-Matton, Anna; Maioli, Silvia. 2022. Alzheimer's research and therapy. 14: . 37
β-Amyloid, Tau, Neurodegeneration Classification and Eligibility for Anti-amyloid Treatment in a Memory Clinic Population
Rosenberg, Anna; Öhlund-Wistbacka, Ulf; Hall, Anette; Bonnard, Alexandre; Hagman, Göran; Rydén, Marie; Thunborg, Charlotta; Wiggenraad, Fleur; Sandebring-Matton, Anna; Solomon, Alina; Kivipelto, Miia. 2022. Neurology. 99: 1-35
27-Hydroxycholesterol, cognition, and brain imaging markers in the FINGER randomized controlled trial
Sandebring-Matton, Anna; Goikolea, Julen; Björkhem, Ingemar; Paternain, Laura; Kemppainen, Nina; Laatikainen, Tiina; Ngandu, Tiia; Rinne, Juha; Soininen, Hilkka; Cedazo-Minguez, Angel; Solomon, Alina; Kivipelto, Miia. 2021. Alzheimer's research and therapy. 13: 56
Change in CAIDE Dementia Risk Score and neuroimaging biomarkers during a 2-year multidomain lifestyle randomized controlled trial: results of a post-hoc subgroup analysis
Stephen, Ruth; Ngandu, Tiia; Liu, Yawu; Peltonen, Markku; Antikainen, Riitta; Kemppainen, Nina; Laatikainen, Tiina; Lötjönen, Jyrki; Rinne, Juha; Strandberg, Timo; Tuomilehto, Jaakko; Vanninen, Ritva; Soininen, Hilkka; Kivipelto, Miia; Solomon, Alina. 2021. Journals of gerontology series a: biological sciences and medical sciences. 76: 1407-1414
Changes in Lifestyle, Behaviors, and Risk Factors for Cognitive Impairment in Older Persons During the First Wave of the Coronavirus Disease 2019 Pandemic in Finland: Results From the FINGER Study
Lehtisalo, Jenni; Palmer, Katie; Mangialasche, Francesca; Solomon, Alina; Kivipelto, Miia; Ngandu, Tiia. 2021. Frontiers in psychiatry. 12: 624125
Development of the First WHO Guidelines for Risk Reduction of Cognitive Decline and Dementia: Lessons Learned and Future Directions
Stephen, Ruth; Barbera, Mariagnese; Peters, Ruth; Ee, Nicole; Zheng, Lidan; Lehtisalo, Jenni; Kulmala, Jenni; Håkansson, Krister; Chowdhary, Neerja; Dua, Tarun; Solomon, Alina; Anstey, Kaarin J; Kivipelto, Miia. 2021. Frontiers in neurology. 12: 763573
Effect of a Multidomain Lifestyle Intervention on Estimated Dementia Risk
Solomon, Alina; Handels, Ron; Wimo, Anders; Antikainen, Riitta; Laatikainen, Tiina; Levälahti, Esko; Peltonen, Markku; Soininen, Hilkka; Strandberg, Timo; Tuomilehto, Jaakko; Kivipelto, Miia; Ngandu, Tiia. 2021. Journal of Alzheimer's disease. 82: 1461-1466
Everyday Life Meaningfulness for the Community-Dwelling Oldest Old During the COVID-19 Pandemic
Tiilikainen, Elisa; Lisko, Inna; Kekkonen, Eija; Solomon, Alina; Ngandu, Tiia; Kivipelto, Miia; Kulmala, Jenni. 2021. Frontiers in psychology. 12: 716428
Facilitators and barriers to implementing lifestyle intervention programme to prevent cognitive decline
Kulmala, J; Rosenberg, A; Ngandu, T; Hemiö, K; Tenkula, T; Hyytiä, A; Vienola, M; Huhtamäki-Kuoppala, M; Saarinen, A; Korkki, S; Laatikainen, T; Solomon, A; Kivipelto, M. 2021. European journal of public health. 31: 816-822
Multidomain interventions: state-of-the-art and future directions for protocols to implement precision dementia risk reduction. A user manual for Brain Health Services-part 4 of 6
Solomon, Alina; Stephen, Ruth; Altomare, Daniele; Carrera, Emmanuel; Frisoni, Giovanni B.; Kulmala, Jenni; Molinuevo, José Luis; Nilsson, Peter; Ngandu, Tiia; Ribaldi, Federica; Vellas, Bruno; Scheltens, Philip; Kivipelto, Miia; European Task Force for Brain Health Services. 2021. Alzheimer's research and therapy. 13: 171
Personal Social Networks of Community-Dwelling Oldest Old During the Covid-19 Pandemic - A Qualitative Study
Kulmala, Jenni; Tiilikainen, Elisa; Lisko, Inna; Ngandu, Tiia; Kivipelto, Miia; Solomon, Alina. 2021. Frontiers in public health. 9: 770965
Quantifying dementia prevention potential in the FINGER randomized controlled trial using the LIBRA prevention index.
Deckers, Kay; Köhler, Sebastian; Ngandu, Tiia; Antikainen, Riitta; Laatikainen, Tiina; Soininen, Hilkka; Strandberg, Timo; Verhey, Frans; Kivipelto, Miia; Solomon, Alina. 2021. Alzheimer's & dementia. 17: 1205-1212
Research diagnostic criteria for Alzheimer's disease: findings from the LipiDiDiet randomized controlled trial
Rosenberg, Anna; Solomon, Alina; Soininen, Hilkka; Visser, Pieter Jelle; Blennow, Kaj; Hartmann, Tobias; Kivipelto, Miia; on behalf of the LipiDiDiet clinical study group [incl. Hallikainen, Ilona; Hallikainen, Merja; Helisalmi, Seppo; Lappalainen, Tarja; Liu, Yawu; Paajanen, Teemu]. 2021. Alzheimer's research and therapy. 13: 64
Telomere length change in a multidomain lifestyle intervention to prevent cognitive decline: a randomized clinical trial
Sindi, Shireen; Solomon, Alina; Kåreholt, Ingemar; Hovatta, Iiris; Antikainen, Riitta; Hänninen, Tuomo; Levälahti, Esko; Laatikainen, Tiina; Lehtisalo, Jenni; Lindström, Jaana; Paajanen, Teemu; Peltonen, Markku; Singh Khalsa, Dharma; Wolozin, Benjamin; Strandberg, Timo; Tuomilehto, Jaakko; Soininen, Hilkka; Ngandu, Tiia; Kivipelto, Miia; for the FINGER Study Group. 2021. Journals of gerontology series a: biological sciences and medical sciences. 76: 491-498
The effect of adherence on cognition in a multidomain lifestyle intervention (FINGER)
Ngandu, Tiia; Lehtisalo, Jenni; Korkki, Saana; Solomon, Alina; Coley, Nicola; Antikainen, Riitta; Bäckman, Lars; Hänninen, Tuomo; Lindström, Jaana; Laatikainen, Tiina; Paajanen, Teemu; Havulinna, Satu; Peltonen, Markku; Neely, Anna Stigsdotter; Strandberg, Timo; Tuomilehto, Jaakko; Soininen, Hilkka; Kivipelto, Miia. 2021. Alzheimer's & dementia. First published: 20 October 2021: 1 - 10
Association of Peripheral Insulin Resistance and Other Markers of Type 2 Diabetes Mellitus With Brain Amyloid Deposition in Healthy Individuals at Risk of Dementia
Pekkala, Timo; Hall, Anette; Mangialasche, Francesca; Kemppainen, Niina; Mecocci, Patrizia; Ngandu, Tiia; Rinne, Juha O; Soininen, Hilkka; Tuomilehto, Jaakko; Kivipelto. Miia; Solomon. Alina 1 2. 2020. Journal of Alzheimer's disease. 76: 1243-1248
Detecting Amyloid Positivity in Elderly With Increased Risk of Cognitive Decline
Pekkala, Timo; Hall, Anette; Ngandu, Tiia; Gils, Mark van; Helisalmi, Seppo; Hänninen, Tuomo; Kemppainen, Nina; Liu, Yawu; Lötjönen, Jyrki; Paajanen, Teemu; Rinne, Juha O; Soininen, Hilkka; Kivipelto, Miia; Solomon, Alina. 2020. Frontiers in aging neuroscience. 12: 228
Late-life personality traits, cognitive impairment, and mortality in a population-based cohort
Neuvonen, Elisa; Hall, Anette; Tolppanen, Anna-Maija; Ngandu, Tiia; Rusanen, Minna; Laatikainen, Tiina; Soininen, Hilkka; Kivipelto, Miia; Solomon, Alina. 2020. International journal of geriatric psychiatry. 35: 989-999
Prescreening for European Prevention of Alzheimer Dementia (EPAD) trial-ready cohort: impact of AD risk factors and recruitment settings
Vermunt, L; Muniz-Terrera, G; Ter Meulen, L; Veal, C; Blennow, K; Campbell, A; Carrié, I; Delrieu, J; Fauria, K; Huesa Rodríguez, G; Ingala, S; Jenkins, N; Molinuevo, JL; Ousset, PJ; Porteous, D; Prins, ND; Solomon, A; Tom, BD; Zetterberg, H; Zwan, M; et al.. 2020. Alzheimer's research and therapy. 12: 8
Third follow-up of the Cardiovascular Risk Factors, Aging and Dementia (CAIDE) cohort investigating determinants of cognitive, physical, and psychosocial wellbeing among the oldest old: the CAIDE85+ study protocol
Barbera, Mariagnese; Kulmala, Jenni; Lisko, Inna; Pietilä, Eija; Rosenberg, Anna; Hallikainen, Ilona; Hallikainen, Merja; Laatikainen, Tiina; Lehtisalo, Jenni; Neuvonen, Elisa; Rusanen, Minna; Soininen, Hilkka; Tuomilehto, Jaakko; Ngandu, Tiia; Solomon, Alina; Kivipelto, Miia. 2020. Bmc geriatrics. 20: 238
White Matter Changes on Diffusion Tensor Imaging in the FINGER Randomized Controlled Trial
Stephen, Ruth; Solomon, Alina; Ngandu, Tiia; Levälahti, Esko; Rinne, Juha O; Kemppainen, Nina; Parkkola, Riitta; Antikainen, Riitta; Strandberg, Timo; Kivipelto, Miia; Soininen, Hilkka; Liu, Yawu. 2020. Journal of Alzheimer's disease. 78: 75-86
World-Wide FINGERS Network: A global approach to risk reduction and prevention of dementia
Kivipelto, M; Mangialasche, F; Snyder, HM; Allegri, R; Andrieu, S; Arai, H; Baker, L; Belleville, S; Brodaty, H; Brucki, SM; Calandri, I; Caramelli, P; Chen, C; Chertkow, H; Chew, E; Choi, SH; Chowdhary, N; Crivelli, L; De La Torre, R; Du, Y; et al. [Incl. Lehtisalo, J; Rosenberg, A; Soininen, H; Solomon, A]. 2020. Alzheimer's & dementia. 16: 1078-1094
Alzheimer's Disease Composite Score: A Post-Hoc Analysis Using Data from the LipiDiDiet Trial in Prodromal Alzheimer's Disease
Hendrix, Suzanne B; Soininen, H; van Hees, AMJ; Ellison, N; Visser, PJ; Solomon, A; Attali, A; Blennow, K; Kivipelto, M; Hartmann, T. 2019. The Journal of prevention of Alzheimer's disease. 6: 232-236
Brain volumes and cortical thickness on MRI in the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER)
Stephen, R; Liu, Y; Ngandu, T; Antikainen, R; Hulkkonen, J; Koikkalainen, J; Kemppainen, N; Lötjönen, J; Levälahti, E; Parkkola, R; Pippola, P; Rinne, J; Strandberg, T; Tuomilehto, J; Vanninen, R; Kivipelto, M; Soininen, H; Solomon, A. 2019. Alzheimer's research and therapy. 11: 53
European Prevention of Alzheimer's Dementia Longitudinal Cohort Study (EPAD LCS): study protocol
Solomon, A; Kivipelto, M; Molinuevo, JL; Tom, B; Ritchie, CW. 2019. BMJ open. 8: e021017
FINGER-elintapaohjelma -toimintamalli kognitiivisen toimintakyvyn tukemiseen
Kivipelto, Miia; Kulmala, Jenni; Lehtisalo, Jenni; Solomon, Alina; Lindström, Jaana; Rauramaa, Rainer; Peltonen, Markku; Laatikainen, Tiina; Havulinna, Satu; Soininen, Hilkka; Tuomilehto, Jaakko; Hänninen, Tuomo; Paajanen, Teemu; Antikainen, Riitta; Strandberg, Timo; Ngandu, Tiia. 2019. Lääkärilehti. 74: 183-186
From prediction to dementia prevention
Solomon, A; Ngandu, T; Kivipelto, M. Teoksessa: Irving, Kate; Hogervorst, Eef; Oliveira, Deborah; Kivipelto, Miia(toim.) , 2019. New Developments in Dementia Prevention Research : State of the Art and Future Possibilities. s. 13-26. Routledge
Long-term dementia risk prediction by the LIBRA score: a 30-year follow-up of the CAIDE study
Deckers, K; Barbera, M; Köhler, S; Ngandu, T; van Boxtel, M; Rusanen, M; Laatikainen, T; Verhey, F; Soininen, H; Kivipelto, M; Solomon, A. 2019. International journal of geriatric psychiatry. 2020; 35: 195-203
Multidomain Interventions to Prevent Cognitive Impairment, Alzheimer's Disease, and Dementia: From FINGER to World-Wide FINGERS
Rosenberg, A; Mangialasche, F; Ngandu, T; Solomon, A; Kivipelto, M. 2019. The Journal of prevention of Alzheimer's disease. 2020; 7: 29-36
Predicting Development of Alzheimer's Disease in Patients with Shunted Idiopathic Normal Pressure Hydrocephalus
Luikku, AJ; Hall, A; Nerg, O; Koivisto, AM; Hiltunen, M; Helisalmi, S; Herukka, SK; Junkkari, A; Sutela, A; Kojoukhova, M; Korhonen, V; Mattila, J; Lötjönen, J; Rummukainen, J; Alafuzoff, I; Jääskeläinen, JE; Remes, AM; Solomon, A; Kivipelto, M; Soininen, H; et al. [Incl. Rauramaa, T; Leinonen, V]. 2019. Journal of Alzheimer's disease. 71: 1233-1243
Prediction models for dementia and neuropathology in the oldest old: the Vantaa 85+ cohort study
Hall, A; Pekkala, T; Polvikoski, T; van Gils, M; Kivipelto, M; Lötjönen, J; Mattila, J; Kero, M; Myllykangas, L; Mäkelä, M; Oinas, M; Paetau, A; Soininen, H; Tanskanen, M; Solomon, A. 2019. Alzheimer's research and therapy. 11: 11
Progression to dementia in memory clinic patients with mild cognitive impairment and normal ß-amyloid
Rosenberg, A; Solomon, A; Jelic, V; Hagman, G; Bogdanovic, N; Kivipelto, M. 2019. Alzheimer's research and therapy. 11: 99
The Effect of Multidomain Lifestyle Intervention on Daily Functioning in Older People
Kulmala, J; Ngandu, T; Havulinna, S; Levälahti, E; Lehtisalo, J; Solomon, A; Antikainen, R; Laatikainen, T; Pippola, P; Peltonen, M; Rauramaa, R; Soininen, H; Strandberg, T; Tuomilehto, J; Kivipelto, M. 2019. Journal of the american geriatrics society. 67: 1138-1144
CAIDE dementia risk score, Alzheimer and cerebrovascular pathology: a population-based autopsy study
Hooshmand, B; Polvikoski, T; Kivipelto, M; Tanskanen, M; Myllykangas, L; Mäkelä, M; Oinas, M; Paetau, A; Solomon, A. 2018. Journal of internal medicine. 283: 597-603
Decreased plasma C-reactive protein levels in APOE E 4 allele carriers
Martiskainen, Henna; Takalo, Mari; Solomon, Alina; Stancáková, Alena; Marttinen, Mikael; Natunen, Teemu; Haapasalo, Annakaisa; Herukka, Sanna-Kaisa; Kuusisto, Johanna; Soininen, Hilkka; Kivipelto, Miia; Laakso, Markku; Hiltunen, Mikko. 2018. Annals of clinical and translational neurology. 5: 1229-1240
Effect of the Apolipoprotein E Genotype on Cognitive Change During a Multidomain Lifestyle Intervention: A Subgroup Analysis of a Randomized Clinical Trial
Solomon, A; Turunen, H; Ngandu, T; Peltonen, M; Levälahti, E; Helisalmi, S; Antikainen, R; Bäckman, L; Hänninen, T; Jula, A; Laatikainen, T; Lehtisalo, J; Lindström, J; Paajanen, T; Pajala, S; Stigsdotter-Neely, A; Strandberg, T; Tuomilehto, J; Soininen, H; Kivipelto, M. 2018. JAMA neurology. 75: 462-470
Multidomain lifestyle intervention benefits a large elderly population at risk for cognitive decline and dementia regardless of baseline characteristics: The FINGER trial
Rosenberg, A; Ngandu, T; Rusanen, M; Antikainen, R; Bäckman, L; Havulinna, S; Hänninen, T; Laatikainen, T; Lehtisalo, J; Levälahti, E; Lindström, J; Paajanen, T; Peltonen, M; Soininen, H; Stigsdotter-Neely, A; Strandberg, T; Tuomilehto, J; Solomon, A; Kivipelto, M. 2018. Alzheimer's & dementia. 14: 263-270
Sleep disturbances and dementia risk: A multicenter study
Sindi, S; Kåreholt, I; Johansson, L; Skoog, J; Sjöberg, L; Wang, HX; Johansson, B; Fratiglioni, L; Soininen, H; Solomon, A; Skoog, I; Kivipelto, M. 2018. Alzheimer's & dementia. 14: 1235-1242
Sleep disturbances and later cognitive status: a multi-centre study
Sindi, S; Johansson, L; Skoog, J; Mattsson, AD; Sjöberg, L; Wang, HX; Fratiglioni, L; Kulmala, J; Soininen, H; Solomon, A; Johansson, B; Skoog, I; Kivipelto, M; Kåreholt, I. 2018. Sleep medicine. 52: 26-33
24-month intervention with a specific multinutrient in people with prodromal Alzheimer's disease (LipiDiDiet): a randomised, double-blind, controlled trial
Soininen Hilkka, Solomon Alina, Jelle Visser Pieter, Hendrix Suzanne B, Blennow Kaj, Kivipelto Miia, Hartmann Tobias, LipiDiDiet clinical study group. 2017. The Lancet Neurology. 16: 965-975
Associations of CAIDE Dementia Risk Score with MRI, PIB-PET measures, and cognition
Stephen R, Liu Y, Ngandu T, Rinne JO, Kemppainen N, Parkkola R, Laatikainen T, Paajanen T, Hänninen T, Strandberg T, Antikainen R, Tuomilehto J, Keinänen Kiukaanniemi S, Vanninen R, Helisalmi S, Levälahti E, Kivipelto M, Soininen H, Solomon A. 2017. Journal of Alzheimer's disease. 59: 695-705
Baseline Telomere Length and Effects of a Multidomain Lifestyle Intervention on Cognition: The FINGER Randomized Controlled Trial
Sindi Shireen, Ngandu Tiia, Hovatta Iiris, Kåreholt Ingemar, Antikainen Riitta, Hänninen Tuomo, Levälahti Esko, Laatikainen Tiina, Lindström Jaana, Paajanen Teemu, Peltonen Markku, Khalsa Dharma Singh, Wolozin Benjamin, Strandberg Timo, Tuomilehto Jaakko, Soininen Hilkka, Kivipelto Miia, Solomon Alina. 2017. Journal of Alzheimer's disease. 59: 1459-1470
Health-related quality of life in a multidomain intervention trial to prevent cognitive decline (FINGER)
Strandberg TE, Levälahti E, Ngandu T, Solomon A, Kivipelto M, Lehtisalo J, Laatikainen T, Soininen H, Antikainen R, Jula A, Tuomilehto J, Peltonen M, Lindström J, Rauramaa R, Pajala S, Hänninen T, Solomon A, Paajanen T, Mangialasche F, FINGER Study Group. 2017. European geriatric medicine. 8: 164-167
Hippocampal Sclerosis and Epilepsy in Elderly Population
Rauramaa Tuomas, Solomon Alina, Pikkarainen Maria, Kälviäinen Reetta, Alafuzoff Irina. 2017. Journal of Alzheimer's disease & Parkinsonism. 7: 384
Midlife Work-Related Stress is Associated with Late-Life Gray Matter Volume Atrophy
Sindi, Shireen; Kåreholt, Ingemar; Spulber, Gabriela; Soininen, Hilkka; Kivipelto, Miia; Solomon, Alina. 2017. Journal of Alzheimer's disease reports. 1: 219-227
Physical Activity and Alzheimer's Disease: A Systematic Review
Stephen Ruth, Hongisto Kristiina, Solomon Alina, Lönnroos Eija. 2017. Journals of gerontology series a: biological sciences and medical sciences. 72: 733-739
Self-rated physical fitness and estimated maximal oxygen uptake in relation to all-cause and cause-specific mortality
Solomon A, Borodulin, Ngandu T, Kivipelto M, Laatikainen T, Kulmala J. 2017. Scandinavian journal of medicine and science in sports. 2018; 28: 532-540
Tutkimusnäytöstä kohti uusia käytäntöjä: Liikunta- ja elintapamuutoksilla muistisairauksia ehkäisemään
Kulmala Jenni, Rosenberg Anna, Ngandu Tiia, Solomon Alina, Kivipelto Miia. 2017. Liikunta ja tiede. 54: 17-21
Association of Vitamin B12, Folate, and Sulfur Amino Acids With Brain Magnetic Resonance Imaging Measures in Older Adults: A Longitudinal Population-Based Study
Hooshmand B, Mangialasche F, Kalpouzos G, Solomon A, Kåreholt I, Smith AD, Refsum H, Wang R, Mühlmann M, Ertl-Wagner B, Laukka EJ, Bäckman L, Fratiglioni L, Kivipelto M. 2016. JAMA psychiatry. 73: 606-613
CAIDE Dementia Risk Score and biomarkers of neurodegeneration in memory clinic patients without dementia.
Enache D, Solomon A, Cavallin L, Kåreholt I, Kramberger MG, Aarsland D, Kivipelto M, Eriksdotter M, Winblad B, Jelic V. 2016. Neurobiology of aging. 42: 124-131
Development of a Late-Life Dementia Prediction Index with Supervised Machine Learning in the Population-Based CAIDE Study
Pekkala Timo, Hall Anette, Lötjönen Jyrki, Mattila Jussi, Soininen Hilkka, Ngandu Tiia, Laatikainen Tiina, Kivipelto Miia, Solomon Alina. 2016. Journal of Alzheimer's disease. 2017; 55: 1055-1067
Estradiol and Cognition in the Cardiovascular Risk Factors, Aging and Dementia (CAIDE) Cohort Study
Imtiaz Bushra, Tolppanen Anna-Maija, Solomon Alina, Soininen Hilkka, Kivipelto Miia. 2016. Journal of Alzheimer's disease. 2017; 56: 453-458
Midlife work-related stress increases dementia risk in later life: the CAIDE 30-year study
Sindi Shireen, Hagman Göran, Håkansson Krister, Kulmala Jenni, Nilsen Charlotta, Kåreholt Ingemar, Soininen Hilkka, Solomon Alina, Kivipelto Miia. 2016. Journals of gerontology series b: psychological sciences and social sciences. 2017; 72: 1044-1053
A 2 year multidomain intervention of diet, exercise, cognitive training, and vascular risk monitoring versus control to prevent cognitive decline in at-risk elderly people (FINGER): a randomised controlled trial
Ngandu Tiia, Lehtisalo Jenni, Solomon Alina, Levälahti Esko, Ahtiluoto Satu, Antikainen Riitta, Bäckman Lars, Hänninen Tuomo, Jula Antti, Laatikainen Tiina, Lindström Jaana, Mangialasche Francesca, Paajanen Teemu, Pajala Satu, Peltonen Markku, Rauramaa Rainer, Stigsdotter-Neely Anna, Strandberg T, Tuomilehto J, Soininen Hilkka, Kivipelto Miia. 2015. The Lancet. 385: 2255-2263
Dementia: Risk prediction models in dementia prevention
Solomon Alina, Soininen Hilkka. 2015. Nature reviews neurology. 11: 375-377
Midlife CAIDE Dementia Risk Score and Dementia-Related Brain Changes up to 30 Years Later on Magnetic Resonance Imaging
Vuorinen Miika, Spulber Gabriela, Soheil Damingir, Niskanen Eini, Ngandu Tiia, Soininen Hilkka, Kivipelto Miia, Soloman Alina. 2015. Journal of Alzheimer's disease. 44: 93-101
Pointing the FINGER at multimodal dementia prevention - Authors' reply
Kivipelto Miia, Mangialasched Francesca, Solomon Alina on behalf of the FINGER Study Group. 2015. The Lancet. 386: 1627
9th Key symposium introduction: Updating Alzheimer's disease diagnosis implications for prevention and treatment
Kivipelto M, Mangialasche F, Solomon A, Johansson G, Lannfelt L, Fratiglioni L, Winblad B. 2014. Journal of internal medicine. 275: 202-203
Advances in the prevention of Alzheimer's disease and dementia
Solomon A, Mangialasche F, Richard E, Andrieu S, Bennett DA, Breteler B, Fratiglioni L, Hooshmand B, Khachaturian AS, Schneider LS, Skoog I, Kivipelto M. 2014. Journal of internal medicine. 275: 229-250
Association between mid- to late life physical fitness and dementia: evidence from the CAIDE study
Kulmala J, Solomon A, Kåreholt I, Ngandu T, Rantanen T, Laatikainen T, Soininen H, Tuomilehto J, Kivipelto M. 2014. Journal of internal medicine. 276: 296-307
Coronary Heart Disease and Cortical Thickness, Gray Matter and White Matter Lesion Volumes on MRI
Vuorinen Miika, Damangir Soheil, Niskanen Eini, Miralbell Julia, Rusanen Minna, Spulber Gabriela, Soininen Hilkka, Kivipelto Miia, Solomon Alina. 2014. PLoS ONE. 9: e109250, 1-9
Late-life cynical distrust, risk of incident dementia, and mortality in a population-based cohort
Neuvonen Elisa, Rusanen Minna, Solomon Alina, Ngandu Tiia, Laatikainen Tiina, Soininen Hilkka, Kivipelto Miia, Tolppanen Anna-Maija. 2014. Neurology. 82: 2205-2212
Leisure-time physical activity from mid- to late life, body mass index, and risk of dementia
Tolppanen Anna-Maija, Solomon Alina, Kulmala Jenni, Kåreholt Ingemar, Ngandu Tiia, Rusanen Minna, Laatikainen Tiina, Soininen Hilkka, Kivipelto Miia. 2014. Alzheimer's & dementia. Epub ahead of print: -
Recruitment and baseline characteristics of participants in the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER)-a randomized controlled lifestyle trial
Ngandu Tiia, Lehtisalo Jenni, Levälahti Esko, Laatikainen Tiina, Lindström Jaana, Peltonen Markku, Solomon Alina, Ahtiluoto Satu, Antikainen Riitta, Hänninen Tuomo, Jula Antti, Mangialasche Francesca, Paajanen Teemu, Pajala Satu, Rauramaa Rainer, Strandberg Timo, Tuomilehto Jaakko, Soininen Hilkka, Kivipelto Miia. 2014. International journal of environmental research and public health. 11: 9345-9360
Vitamin D in relation to cognitive impairment, cerebrospinal fluid biomarkers, and brain volumes
Hooshmand Babak, Lökk Johan, Solomon Alina, Mangialasche Francesca, Miralbell Julia, Spulber Gabriela, Annerbo Sylvia, Andreasen Niels, Winblad Bengt, Cedazo-Minguez Angel, Wahlund Lars-Olof, Kivipelto Miia. 2014. Journals of gerontology series a: biological sciences and medical sciences. -: 7 s.
Changes in vascular factors 28 years from midlife and late-life cortical thickness
Vuorinen M, Kåreholt I, Julkunen V, Spulber G, Niskanen E, Paajanen T, Soininen H, Kivipelto M, Solomon A. 2013. Neurobiology of aging. 34: 100-109
Cholesterol, statins, and late-life cognitive disorders.
Solomon A, Kivipelto M. Teoksessa: Yaffe Kristine(toim.) , 2013. Chronic Medical Disease and Cognitive Aging. Toward a healthy body and brain. s. 13-39. Oxford University Press
Diagnostic power of 24S-hydroxycholesterol in cerebrospinal fluid: Candidate marker of brain health
Leoni V, Solomon A, Lövgren-Sandholm A, Blennow K, Hansson O, Wahlund L-O, Kivipelto M, Björkhem I. 2013. Journal of Alzheimer's disease. 36: 739-747
History of medically treated diabetes and risk of Alzheimer disease in a nationwide case-control study
Tolppanen Anna-Maija, Lavikainen Piia, Solomon Alina, Kivipelto Miia, Uusitupa Matti, Soininen Hilkka, Hartikainen Sirpa. 2013. Diabetes care. 36: 2015-2019
Incidence of stroke in people with Alzheimer disease. A national register-based approach
Tolppanen Anna-Maija, Lavikainen Piia, Solomon Alina, Kivipelto Miia, Soininen Hilkka, Hartikainen Sirpa. 2013. Neurology. 80: 353-358
Plasma homocysteine, Alzheimer and cerebrovascular pathology: a population-based autopsy study
Hooshmand B, Polvikoski T, Kivipelto M, Tanskanen M, Myllykangas L, Erkinjuntti T, Mäkelä M, Oinas M, Paetau A, Scheltens P, van Straaten ECW, Sulkava R, Solomon A. 2013. Brain. 136: 2707-2716
Prevention of Alzheimer's Disease: Moving backward through the lifespan
Solomon A, Kivipelto M, Soininen H. 2013. Journal of Alzheimer's disease. 33: S465-S469
Serum levels of vitamin E forms and risk of cognitive impairment in a Finnish cohort of older adults
Mangialasche F, Solomon A, Kåreholt I, Hooshmand B, Cecchetti R, Fratiglioni L, Soininen H, Laatikainen T, Mecocci P, Kivipelto M. 2013. Experimental gerontology. 48: 1428-1435
The Finnish Geriatric intervention study to prevent cognitive impairment and disability (FINGER): Study design and progress
Kivipelto M, Solomon A, Ahtiluoto S, Ngandu T, Lehtisalo J, Antikainen R, Bäckman L, Hänninen T, Jula A, Laatikainen T, Lindström J, Mangialasche F, Nissinen A, Paajanen T, Pajala S, Peltonen M, Rauramaa R, Stigsdotter-Neely A, Strandberg T, Tuomilehto J, Soininen H. 2013. Alzheimer's & dementia. 9: 657-665
Validity of dementia and Alzheimer disease diagnoses in Finnish national registers
Solomon A, Ngandu T, Soininen H, Hallikainen M, Kivipelto M, Laatikainen T. 2013. Alzheimer's & dementia. Epub: 1-7
Associations between serum homocysteine, holotranscobalamin, folate and cognition in the elderly: a longitudinal study
Hooshmand B, Solomon A, Kåreholt I, Rusanen M, Hänninen T, Leivistä J, Winblad B, Laatikainen T, Soininen H, Kivipelto M. 2012. Journal of internal medicine. 271: 204-212
Dementia prevention: current epidemiological evidence and future perspective
Mangialasche F, Kivipelto M, Solomon M, Fratiglioni L. 2012. Alzheimer's research and therapy. 4: 1-8
Differences in brain cholestero metabolism and insulin in two subgroups of patients with different CSF biomarkers but similar white matter lesions suggest different pathogenic mechanisms
Besga A, Cedazo-Minguez A, Kåreholt I, Solomon A, Björkhem I, Winblad B, Leoni V, Hooshmand B, Spulber G, Gonzales-Pinto A, Kivipelto M, Wahlund LO. 2012. Neuroscience letters. 510: 121-126
Methodological challenges in designing dementia prevention trials - The European Dementia Prevention Initiative (EDPI)
Richard E, Andrieu S, Solomon A, Mangialasche F, Ahtiluoto S, Moll van Charante EP, Coley N, Fratiglioni L, Stigsdotter Neely A, Vellas B, van Gool WA, Kivipelto M. 2012. Journal of the neurological sciences. 322: 64-70
Midlife Vascular Risk Factors and Alzheimer's Disease: Evidence from Epidemiological Studies
Tolppanen AM, Solomon A, Soininen H, Kivipelto M. 2012. Journal of Alzheimer's disease. 32: 531-40
Midlife rheumatoid arthritis increases the risk of cognitive impairment two decades later: A population-based study
Wallin K, Solomon A, Kåreholt I, Tuomilehto J, Soininen H, Kivipelto M. 2012. Journal of Alzheimer's disease. 31: 669-676
Practical Lessons from Amyloid Immunotherapy Trials in Alzheimer Disease
Solomon A, Akenine U, Andreasen N, Mangialasche F, Wimo A, Jelic V, Kivipelto M, Winblad B. 2012. Current alzheimer research. 9: 1126-1134
Changes in vascular risk factors from midlife to late life and white matter lesions: A 20-year follow-up study
Vuorinen Miika, Solomon Alina, Rovio Suvi, Nieminen Lasse, Kåreholt Ingemar, Tuomilehto Jaakko, Soininen Hilkka, Kivipelto Miia. 2011. Dementia and geriatric cognitive disorders. 31: 119-125
Comorbidity and the rate of cognitive decline in patients with Alzheimer dementia
Solomon A, Dobranici L, Kåreholt I, Tudose C, Lazarescu M. 2011. International journal of geriatric psychiatry. 26: 1244-1251
Cost-effectiveness of a health intervention program with risk reductions for getting demented: Results of a Markow model in a Swedish/Finnish setting
Zhang Y, Kivipelto M, Solomon A, Wimo A. 2011. Journal of Alzheimer's disease. 26: 735-744
IAGG Workshop: Health promotion program on prevention of late onset dementia
Andrieu S, Aboderin I, Baeyens J-P, Beard J, Benetos A, Berrut G, Brainin M, Cha HB, Chen L-K, Forette B, Forette F, Franco A, Fratigkioni L, Gillette-Guyonnet S, Gold G, Gomez F, Guimaraes R, Gustafson D, Khachaturian A, Luchsinger J, Mangialasche F, Mathiex-Fortunet H, Michel J-P, Richard E, Schneider LS, Solomon A, Vellas B. 2011. Journal of nutrition health and aging. 15: 562-575
Alzheimer's disease: clinical trials and drug development
Mangialasche F, Solomon A, Winblad B, Mecocci P & Kivipelto M. 2010. The Lancet Neurology. 9: 702-16
Diabetes, Alzheimer disease, and vascular dementia: a population-based neuropathologic study
Ahtiluoto S, Polvikoski T, Peltonen M, Solomon A, Tuomilehto J, Winblad B, Sulkava R & Kivipelto M. 2010. Neurology. 75: 1195-1202
Homocysteine and holotranscobalamin and the risk of Alzheimer disease
Hooshmand B, Solomon A, Kåreholt I, Leivistä J, Rusanen M, Ahtiluoto S, Winblad B, Laatikainen T, Soininen H & Kivipelto M. 2010. Neurology. 75: 1408-1414
Links between ApoE, brain cholesterol metabolism, tau and amyloid beeta-peptide in patients with cognitive impairment
Leoni V, Solomon A & Kivipelto M. 2010. Biochemical society transactions. 38: 1021-2025
Lipid-Lowering Treatment Is Related to Decreased Risk of Dementia: A Population-Based Study (FINRISK)
Solomon A, Sippola R, Soininen H, Wolozin B, Tuomilehto J, Laatikainen T & Kivipelto M. 2010. Neurodegenerative diseases. 7: 180-182
Cholesterol and Late-Life Cognition. An Epidemiological and Clinical Approach
Solomon A. 2009. Kuopion yliopisto. Neurologian klinikan julkaisusarja, No
Midlife serum cholesterol and increased risk of Alzheimer's and vascular dementia three decades later
Solomon A, Kivipelto M, Wolozin B, Zhou J, Whitmer RA. 2009. Dementia and geriatric cognitive disorders. 28: 75-80
Levels of ApoE in cerebrospinal fluid are correlated with Tau and 24S-hydroxycholesterol in patients with cognitive disorders
Shafaati M, Solomon A, Kivipelto M, Björkhem I, Leoni V. 2007. Neuroscience letters. 425: 78-82
Serum cholesterol changes after midlife and late-life cognition. Twenty-one-year follow-up study
Solomon A, Kåreholt I, Ngandu T, Winblad B, Nissinen A, Tuomilehto J, Soininen H, Kivipelto M. 2007. Neurology. 68: 751-756
Alzheimer's Disease: back to the future
Kivipelto M, Solomon A, Winbland B. 2006. Acta neurologica scandinavica: supplementum. 114: 119-120
Cerebral embolism and Alzheimer¿s disease
Kivipelto M, Solomon A. 2006. BMJ international edition
Cholesterol as a risk factor for Alzheimer¿s disease - epidemiological evidence
Kivipelto M, Solomon A. 2006. Acta neurologica scandinavica: supplementum. 114: 50-57
The new cholesterol controversy - a little bit of history repeating?
Kivipelto M, Solomon A, Blennow K, Olsson AG, Winblad B. 2006. Acta neurologica scandinavica: supplementum. 114: 1-2

University of Eastern Finland Joensuu, Kuopio © University of Eastern Finland

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Alina Solomon

Research groups

Projects

Alzheimer's disease genetic risk score and neuroimaging in the FINGER lifestyle trial

Association of tooth location, occlusal support and chewing ability with cognitive decline and incident dementia

Cognitive reserve, cortisol, and Alzheimer's disease biomarkers: A memory clinic study

Diurnal cortisol, neuroinflammation, and neuroimaging visual rating scales in memory clinic patients

Diverging medical and legal perceptions of the need for legal guardianship in people with dementia: A qualitative study

Evaluation of Clinical Meaningfulness of Fortasyn Connect in Terms of “Time Saved”

Machine learning prediction of future amyloid beta positivity in amyloid-negative individuals

Nutrition guidance within a multimodal intervention improves diet quality in prodromal Alzheimer’s disease: Multimodal Preventive Trial for Alzheimer’s Disease (MIND-ADmini)

Sleep disturbances and change in multiple cognitive domains among older adults: A multicentre study of five Nordic cohorts

Validation, Deployment, and Real-World Implementation of a Modular Toolbox for Alzheimer’s Disease Detection and Dementia Risk Reduction: The AD-RIDDLE Project

27‐hydroxycholesterol promotes oligodendrocyte maturation: Implications for hypercholesterolemia‐associated brain white matter changes

Association between Longitudinal Cerebrospinal Fluid Alzheimer's Biomarkers and the Lifestyle for Brain Health (LIBRA) Index: Findings from the European Prevention of Alzheimer's Dementia Cohort Study (EPAD LCS)

Association of tooth count with cognitive decline and dementia in the Finnish adult population

Combined Evidence for a Long-Term, Clinical Slowing Effect of Multinutrient Intervention in Prodromal Alzheimer’s Disease: Post-Hoc Analysis of 3-Year Data from the LipiDiDiet Trial

Dementia prevention in memory clinics: recommendations from the European task force for brain health services

Life-course stress, cognition, and diurnal cortisol in memory clinic patients without dementia

Longitudinal study of Alzheimer's disease biomarkers, allostatic load, and cognition among memory clinic patients

Multimodal Precision Prevention - A New Direction in Alzheimer’s Disease

Precision medicine in neurodegeneration: the IHI-PROMINENT project

Response to “Comment on ‘Dementia prevention: The potential long-term cost-effectiveness of the FINGER prevention program’”

Study design and methods: US study to protect brain health through lifestyle intervention to reduce risk (US POINTER)

Associations of Depressive Symptoms and Cognition in the FINGER Trial: A Secondary Analysis of a Randomised Clinical Trial

Cortisol, cognition and Alzheimer’s disease biomarkers among memory clinic patients

Dementia Risk Scores and Their Role in the Implementation of Risk Reduction Guidelines

Diabetes and Dementia: Spotlight on Multidomain Lifestyle Strategies

Effect of a multi-domain lifestyle intervention on cardiovascular risk in older people: the FINGER trial

Metabolome-wide association study on ABCA7 indicates a role of ceramide metabolism in Alzheimer’s disease

Multimodal Preventive Trial for Alzheimer’s Disease: MIND-ADmini Pilot Trial Study Design and Progress

New insights into the genetic etiology of Alzheimer’s disease and related dementias

Periodontal health, cognitive decline, and dementia: A systematic review and meta‐analysis of longitudinal studies

Psychosocial determinants for adherence to a healthy lifestyle and intervention participation in the FINGER trial: an exploratory analysis of a randomised clinical trial

Serum Thioredoxin-80 is associated with age, ApoE4, and neuropathological biomarkers in Alzheimer’s disease: a potential early sign of AD

β-Amyloid, Tau, Neurodegeneration Classification and Eligibility for Anti-amyloid Treatment in a Memory Clinic Population

27-Hydroxycholesterol, cognition, and brain imaging markers in the FINGER randomized controlled trial

Change in CAIDE Dementia Risk Score and neuroimaging biomarkers during a 2-year multidomain lifestyle randomized controlled trial: results of a post-hoc subgroup analysis

Changes in Lifestyle, Behaviors, and Risk Factors for Cognitive Impairment in Older Persons During the First Wave of the Coronavirus Disease 2019 Pandemic in Finland: Results From the FINGER Study

Development of the First WHO Guidelines for Risk Reduction of Cognitive Decline and Dementia: Lessons Learned and Future Directions

Effect of a Multidomain Lifestyle Intervention on Estimated Dementia Risk

Everyday Life Meaningfulness for the Community-Dwelling Oldest Old During the COVID-19 Pandemic

Facilitators and barriers to implementing lifestyle intervention programme to prevent cognitive decline

Multidomain interventions: state-of-the-art and future directions for protocols to implement precision dementia risk reduction. A user manual for Brain Health Services-part 4 of 6

Personal Social Networks of Community-Dwelling Oldest Old During the Covid-19 Pandemic - A Qualitative Study

Quantifying dementia prevention potential in the FINGER randomized controlled trial using the LIBRA prevention index.

Research diagnostic criteria for Alzheimer's disease: findings from the LipiDiDiet randomized controlled trial

Telomere length change in a multidomain lifestyle intervention to prevent cognitive decline: a randomized clinical trial

The effect of adherence on cognition in a multidomain lifestyle intervention (FINGER)

Association of Peripheral Insulin Resistance and Other Markers of Type 2 Diabetes Mellitus With Brain Amyloid Deposition in Healthy Individuals at Risk of Dementia

Detecting Amyloid Positivity in Elderly With Increased Risk of Cognitive Decline

Late-life personality traits, cognitive impairment, and mortality in a population-based cohort

Prescreening for European Prevention of Alzheimer Dementia (EPAD) trial-ready cohort: impact of AD risk factors and recruitment settings

Third follow-up of the Cardiovascular Risk Factors, Aging and Dementia (CAIDE) cohort investigating determinants of cognitive, physical, and psychosocial wellbeing among the oldest old: the CAIDE85+ study protocol

White Matter Changes on Diffusion Tensor Imaging in the FINGER Randomized Controlled Trial

World-Wide FINGERS Network: A global approach to risk reduction and prevention of dementia

Alzheimer's Disease Composite Score: A Post-Hoc Analysis Using Data from the LipiDiDiet Trial in Prodromal Alzheimer's Disease

Brain volumes and cortical thickness on MRI in the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER)

European Prevention of Alzheimer's Dementia Longitudinal Cohort Study (EPAD LCS): study protocol

FINGER-elintapaohjelma -toimintamalli kognitiivisen toimintakyvyn tukemiseen

From prediction to dementia prevention

Long-term dementia risk prediction by the LIBRA score: a 30-year follow-up of the CAIDE study

Multidomain Interventions to Prevent Cognitive Impairment, Alzheimer's Disease, and Dementia: From FINGER to World-Wide FINGERS

Predicting Development of Alzheimer's Disease in Patients with Shunted Idiopathic Normal Pressure Hydrocephalus

Prediction models for dementia and neuropathology in the oldest old: the Vantaa 85+ cohort study

Progression to dementia in memory clinic patients with mild cognitive impairment and normal ß-amyloid

The Effect of Multidomain Lifestyle Intervention on Daily Functioning in Older People

CAIDE dementia risk score, Alzheimer and cerebrovascular pathology: a population-based autopsy study

Decreased plasma C-reactive protein levels in APOE E 4 allele carriers

Effect of the Apolipoprotein E Genotype on Cognitive Change During a Multidomain Lifestyle Intervention: A Subgroup Analysis of a Randomized Clinical Trial

Multidomain lifestyle intervention benefits a large elderly population at risk for cognitive decline and dementia regardless of baseline characteristics: The FINGER trial

Sleep disturbances and dementia risk: A multicenter study

Sleep disturbances and later cognitive status: a multi-centre study

24-month intervention with a specific multinutrient in people with prodromal Alzheimer's disease (LipiDiDiet): a randomised, double-blind, controlled trial

Associations of CAIDE Dementia Risk Score with MRI, PIB-PET measures, and cognition

Baseline Telomere Length and Effects of a Multidomain Lifestyle Intervention on Cognition: The FINGER Randomized Controlled Trial

Health-related quality of life in a multidomain intervention trial to prevent cognitive decline (FINGER)

Hippocampal Sclerosis and Epilepsy in Elderly Population

Midlife Work-Related Stress is Associated with Late-Life Gray Matter Volume Atrophy