Ashik Jawahar Deen - UEFConnect

Refine your search

Information Publications

Research groups

Mechanisms of cancer and metabolic disease (Levon… 01.01.2010 -

Keywords

apoptosis autophagy drug resistance KEAP1 lung cancer Nrf2 oxidative stress proteomics

Publications

16/16 items

Epithelial-mesenchymal Transition (EMT) and the Effect of Atorvastatin on it in ARPE-19 cells
Mysore, Yashavanthi; Hytti, Maria; Deen, Ashik Jawahar; Ranta-aho, Sofia; Piippo, Niina; Toppila, Maija; Loukovaara, Sirpa; Harju, Niina; Kauppinen, Anu. 2024. Cell biochemistry and biophysics. 82: 1523-1536 A1 Journal article (refereed), original research
Making Multiplexed Imaging Flexible: Combining Essential Markers With Established Antibody Panels
Deen, Ashik Jawahar; Thorsson, Johan; O’Roberts, Eleanor M; Panshikar, Pranauti; Ullman, Tony; Krantz, David; Oses, Carolina; Stadler, Charlotte. 2024. Journal of histochemistry and cytochemistry. 72: 517-544 A1 Journal article (refereed), original research
Oncogenic KEAP1 mutations activate TRAF2-NFκB signaling to prevent apoptosis in lung cancer cells
Deen, Ashik Jawahar; Adinolfi, Simone; Härkönen, Jouni; Patinen, Tommi; Liu, Xiaonan; Laitinen, Tuomo; Takabe, Piia; Kainulainen, Kirsi; Pasonen-Seppänen, Sanna; Gawriyski, Lisa M; Arasu, Uma Thanigai; Selvarajan, Ilakya; Mäkinen, Petri; Laitinen, Hanna; Kansanen, Emilia; Kaikkonen, Minna U; Poso, Antti; Varjosalo, Markku; Levonen, Anna-Liisa. 2024. Redox biology. 69: A1 Journal article (refereed), original research
A pan-cancer analysis shows immunoevasive characteristics in NRF2 hyperactive squamous malignancies
Härkönen, Jouni; Pölönen, Petri; Deen, Ashik Jawahar; Selvarajan, Ilakya; Teppo, Hanna-Riikka; Dimova, Elitsa Y.; Kietzmann, Thomas; Ahtiainen, Maarit; Väyrynen, Juha P.; Väyrynen, Sara A.; Elomaa, Hanna; Tynkkynen, Niko; Eklund, Tiia; Kuopio, Teijo; Talvitie, Eva-Maria; Taimen, Pekka; Kallajoki, Markku; Kaikkonen, Minna U.; Heinäniemi, Merja; Levonen, Anna-Liisa. 2023. Redox biology. 61: A1 Journal article (refereed), original research
The KEAP1-NRF2 pathway: Targets for therapy and role in cancer
Adinolfi, Simone; Patinen, Tommi; Jawahar Deen, Ashik; Pitkänen, Sini; Härkönen, Jouni; Kansanen, Emilia; Küblbeck, Jenni; Levonen, Anna-Liisa. 2023. Redox biology. 63: A2 Review article, Literature review, Systematic review
Integrative analysis of liver-specific non-coding regulatory SNPs associated with the risk of coronary artery disease
Selvarajan, Ilakya; Toropainen, Anu; Garske, Kristina M.; López Rodríguez, Maykel; Ko, Arthur; Miao, Zong; Kaminska, Dorota; Õunap, Kadri; Örd, Tiit; Ravindran, Aarthi; Liu, Oscar H.; Moreau, Pierre R.; Jawahar Deen, Ashik; Männistö, Ville; Pan, Calvin; Levonen, Anna-Liisa; Lusis, Aldons J.; Heikkinen, Sami; Romanoski, Casey E.; Pihlajamäki, Jussi; Pajukanta, Päivi; Kaikkonen, Minna U.. 2021. American journal of human genetics. 108: 411-430 A1 Journal article (refereed), original research
The calcium-activated chloride channel-associated protein rCLCA2 is expressed throughout rat epidermis, facilitates apoptosis and is downmodulated by UVB
Hämäläinen, L; Bart, G; Takabe, P; Rauhala, L; Deen, A; Pasonen-Seppänen, S; Kärkkäinen, E; Kärnä, R; Kumlin, T; Tammi, M; I; Tammi, RH. 2021. Histochemistry and cell biology. 5: 605-615 A1 Journal article (refereed), original research
Effects of mutations in the post-translational modification sites on the trafficking of hyaluronan synthase 2 (HAS2)
Melero-Fernandez de Mera, RM; Arasu, UT; Kärnä, R; Oikari, S; Rilla, K; Vigetti, D; Passi, A; Heldin, P; Tammi, MI; Deen, AJ. 2019. Matrix biology. 80: 85-103 A1 Journal article (refereed), original research
HAS3-induced extracellular vesicles from melanoma cells stimulate IHH mediated c-Myc upregulation via the hedgehog signaling pathway in target cells
Arasu, UT; Deen, AJ; Pasonen-Seppänen, S; Heikkinen, S; Lalowski, M; Kärnä, R; Härkönen, K; Mäkinen, P; Lázaro-Ibáñez, E; Siljander, PR; Oikari, S; Levonen, AL; Rilla, K. 2019. Cellular and molecular life sciences. [Published: 09 December 2019]: 1-23 A1 Journal article (refereed), original research
Nrf2 and SQSTM1/p62 jointly contribute to mesenchymal transition and invasion in glioblastoma
Pölönen, P; Jawahar Deen, A; Leinonen, HM; Jyrkkänen, HK; Kuosmanen, S; Mononen, M; Jain, A; Tuomainen, T; Pasonen-Seppänen, S; Hartikainen, JM; Mannermaa, A; Nykter, M; Tavi, P; Johansen, T; Heinäniemi, M; Levonen, AL. 2019. Oncogene. 38: 7473-7490 A1 Journal article (refereed), original research
Regulation of stress signaling pathways by protein lipoxidation
Patinen, Tommi; Adinolfi, Simone; Cortés, Carlos Cruz; Härkönen, Jouni; Jawahar Deen, Ashik; Levonen, Anna-Liisa. 2019. Redox biology. 23: 1-8 A2 Review article, Literature review, Systematic review
Regulation of stress signaling pathways by nitro-fatty acids
Deen, Ashik Jawahar; Sihvola, Virve; Härkönen, Jouni; Patinen, Tommi; Adinolfi, Simone; Levonen, Anna-Liisa. 2018. Nitric oxide-biology and chemistry. 78: 170-175 A2 Review article, Literature review, Systematic review
Regulation of hyaluronan synthesis: role of hyaluronan synthase trafficking and UDP-sugars
Jawahar Deen Ashik. 2016. Publications of the University of Eastern Finland. Dissertations in Health Sciences G5 Doctoral dissertation (article)
Fluorescence Resonance Energy Transfer (FRET) and Proximity Ligation Assays Reveal Functionally Relevant Homo-and Heteromeric Complexes among Hyaluronan Synthases HAS1, HAS2, and HAS3
Bart Genevieve, Vico Nuria Ortega, Hassinen Antti, Pujol Francois M., Deen Ashik Jawahar, Ruusala Aino, Tammi Raija H., Squire Anthony, Heldin Paraskevi, Kellokumpu Sakari, Tammi Markku I.. 2015. Journal of biological chemistry. 290: 11479-11490 A1 Journal article (refereed), original research
Rab10-mediated endocytosis of the hyaluronan synthase HAS3 regulates hyaluronan synthesis and cell adhesion to collagen
Deen Ashik Jawahar, Rilla Kirsi, Oikari Sanna, Kärnä Riikka, Bart Genevieve, Häyrinen Jukka, Bathina Avinash Rahul, Ropponen Antti, Makkonen Katri, Tammi Raija H, Tammi Markku I. 2014. Journal of biological chemistry. 289: 8375-89 A1 Journal article (refereed), original research
Hyaluronan production enhances shedding of plasma membrane-derived microvesicles
Rilla K, Pasonen-Seppänen S, Deen AJ, Koistinen VVT, Wojciechowski S, Oikari S, Kärnä R, Bart G, Törrönen K, Tammi RH, Tammi MI. 2013. Experimental cell research. 319: 2006-2018 A1 Journal article (refereed), original research