Astrid Subrizi
Academy Research Fellow
School of Pharmacy, Faculty of Health Sciences
I study and develop ocular drug delivery systems. I am interested in the design and functionality of nanocarriers, in the selection of targeting moieties that facilitate safe and precise delivery of drugs to ocular tissues, and in the investigation of ocular barriers and their effects on ocular pharmacokinetics.
Research groups
Projects
Publications
19/19 items-
Injectable biodegradable silica hydrogel depot for dexamethasone delivery in the eye via subconjunctival administration
Pollari, Ville-Matias; Valtari, Annika; Marttila, Lauri; Vellonen, Kati-Sisko; Akieh-Pirkanniemi, Marceline; Jokinen, Mika; Leino, Lasse; Subrizi, Astrid; Urtti, Arto, 2026, International journal of pharmaceutics, 694, 126735. A1 Journal article (refereed), original research -
Novel in vitro model for intravitreal drug dissolution and release studies of small molecules and their long-acting formulations
Sorsa, Teemu; del Amo, Eva M.; Sadeghi, Amir; Laitinen, Jonna; Pilipenko, Iuliia; Urtti, Arto; Subrizi, Astrid, 2025, Journal of controlled release, 383, 113823. A1 Journal article (refereed), original research -
Rapid elimination of suprachoroidally injected small molecule drugs into the systemic blood circulation
Laitinen, Jonna; Valkama, Eetu; Valtari, Annika; Toropainen, Elisa; Koskela, Ali; Kolehmainen, Ida; Puranen, Jooseppi; del Amo, Eva M.; Vellonen, Kati-Sisko; Subrizi, Astrid; Urtti, Arto, 2025, European journal of pharmaceutical sciences, 215, 107349. A1 Journal article (refereed), original research -
Selection of locally administered ocular tissue-targeting RNA aptamers using in vivo SELEX
Stenberg, Katja; Korhonen, Sonja; Seemab, Umair; Dupont, Daniel Miotto; Kjems, Jørgen; Honkakoski, Paavo; Subrizi, Astrid, 2025, European journal of pharmaceutical sciences, 212, 107217. A1 Journal article (refereed), original research -
Thermoresponsive Hydrogels with Tunable Viscoelasticity for Extended Ocular Drug Delivery
Pilipenko, Iuliia; Sorsa, Teemu; Valtari, Annika; Posio, Susanna; Vellonen, Kati-Sisko; Subrizi, Astrid; Hietala, Sami; Ruponen, Marika; Urtti, Arto, 2025, Biomacromolecules, 26, 6, 3721-3731. A1 Journal article (refereed), original research -
Mathematical Models of Ocular Drug Delivery
Sadeghi, Amir; Subrizi, Astrid; del Amo, Eva M; Urtti, Arto, 2024, Investigative ophthalmology and visual science, 65, 11, 28. A2 Review article, Literature review, Systematic review -
PL3 CendR peptide shows specific uptake in cultured Y79 retinoblastoma cells with nucleolar accumulation
Korhonen, Sonja; Bosch, Stef; Erkinheimo, Antero; Lajunen, Tatu; Rilla, Kirsi; Teesalu, Tambet; Subrizi, Astrid; Ruponen, Marika; Urtti, Arto; Reinisalo, Mika, 2024, European journal of pharmaceutical sciences, 201, 106866. A1 Journal article (refereed), original research -
Targeting ocular tissues with intravenously administered aptamers selected by in vivo SELEX
Korhonen, Sonja; Stenberg, Katja; Seemab, Umair; Bartos, Piia; Mäkiniemi, Katariina; Kjems, Jørgen; Dupont, Daniel Miotto; Subrizi, Astrid, 2024, Molecular therapy nucleic acids, 35, 4, 102352. A1 Journal article (refereed), original research -
Intravitreal CendR peptides target laser-induced choroidal neovascularization sites in mice
Puranen, Jooseppi; Korhonen, Sonja; Haugas, Maarja; Lingasamy, Prakash; Teesalu, Tambet; Subrizi, Astrid; Urtti, Arto; Ruponen, Marika; Reinisalo, Mika, 2023, Journal of controlled release, 360, 810-817. A1 Journal article (refereed), original research -
Tailoring surface properties of liposomes for dexamethasone intraocular administration
Al-Amin, M.D.; Mastrotto, Francesca; Subrizi, Astrid; Sen, Merve; Turunen, Tiina; Arango-Gonzalez, Blanca; Ueffing, Marius; Malfanti, Alessio; Urtti, Arto; Salmaso, Stefano; Caliceti, Paolo, 2023, Journal of controlled release, 354, 323-336. A1 Journal article (refereed), original research