Carsten Carlberg
Professor
Professor of Biochemistry
Institute of Biomedicine, School of Medicine, Faculty of Health Sciences
[email protected] | +358 40 355 3062
The research of Carsten Carlberg is directed to gene regulation and epigenetics by vitamin D.
Over 245 of his publications are listed in the Science Citation Index. These have been cited more than 11,000 times leading to h-index of 58 (Web of Science/Publons). So far he finished the supervision of 13 post-doctoral fellows, 19 doctoral students (18 PhD, 1 MD) and 32 MSc students.
Carsten Carlberg published textbooks on “Mechanisms of Gene Regulation”, “Nutrigenomics”, “Human Epigenomics” and “Cancer Biology”.
Research groups
Publications
195/195 items-
Gesund bleiben und elegant altern
Carlberg, Carsten. 2025. . . Springer E2 Popularised monograph -
Nutrigenomics: How Science Works
Carlberg, Carsten; Molnár, Ferdinand. 2025. . 2nd ed.. Springer D5 Textbook, professional manual or guide -
Transcriptomic profiling of immune modulation induced by vitamin D3 in the VitDPAS and VitDHiD cohort studies
Gospodarska, Emilia; Dastidar, Ranjini Ghosh; Jaroslawska, Julia; Rybiński, Maciej; Raczyk, Marianna; Tokarczyk-Malesa, Kornelia; Romaszko, Jerzy; Carlberg, Carsten. 2025. Scientific reports. 15: . 17334 A1 Journal article (refereed), original research -
A Nutrigenomic View on the Premature-Aging Disease Fanconi Anemia
Velleuer, Eunike; Carlberg, Carsten. 2024. Nutrients. 16: . 2271 A2 Review article, Literature review, Systematic review -
Aging : How Science Works
Carlberg, Carsten; Ulven, Stine M.; Velleuer, Eunike. 2024. . . Springer D5 Textbook, professional manual or guide -
Anti-Müllerian hormone: biology and role in endocrinology and cancers
Gowkielewicz, Marek; Lipka, Aleksandra; Zdanowski, Wojciech; Waśniewski, Tomasz; Majewska, Marta; Carlberg, Carsten. 2024. Frontiers in endocrinology. 15: . 1468364 A2 Review article, Literature review, Systematic review -
Die molekulare Basis von Gesundheit
Carlberg, Carsten. 2024. . . Springer E2 Popularised monograph -
Evaluation of the vitamin D response index in a Saudi cohort
AlGhamdi, Shareefa A; Ghosh Dastidar, Ranjini; Rybiński, Maciej; Alsufiani, Hadeil M; Khoja, Sawsan O; Enaibsi, Nusaibah N; Saif, Safa F; Carlberg, Carsten. 2024. Saudi pharmaceutical journal. 32: A1 Journal article (refereed), original research -
Gene Regulation and Epigenetics : How Science Works
Carlberg, Carsten. 2024. . . Springer D5 Textbook, professional manual or guide -
In vivo vitamin D target genes interconnect key signaling pathways of innate immunity
Jaroslawska, Julia; Dastidar, Ranjini Ghosh; Carlberg, Carsten. 2024. PLoS ONE. 19: . e0306426 A1 Journal article (refereed), original research -
In vivo vitamin D targets reveal the upregulation of focal adhesion-related genes in primary immune cells of healthy individuals
Ghosh Dastidar, Ranjini; Jaroslawska, Julia; Malinen, Marjo; Tuomainen, Tomi Pekka; Virtanen, Jyrki K; Bendik, Igor; Carlberg, Carsten. 2024. Scientific reports. 14: . 17552 A1 Journal article (refereed), original research -
Vitamin D and Aging: Central Role of Immunocompetence
Carlberg, Carsten; Velleuer, Eunike. 2024. Nutrients. 16: A2 Review article, Literature review, Systematic review -
Concepts of multi-level dynamical modelling: understanding mechanisms of squamous cell carcinoma development in Fanconi anemia
Velleuer, Eunike; Domínguez-Hüttinger, Elisa; Rodríguez, Alfredo; Harris, Leonard A; Carlberg, Carsten. 2023. Frontiers in genetics. 14: . 1254966 A1 Journal article (refereed), original research -
Epigenetik des Menschen
Carlberg, Carsten; Molnár, Ferdinand. 2023. . . Springer Spektrum D5 Textbook, professional manual or guide -
Genomic signaling of vitamin D
Carlberg, Carsten. 2023. Steroids. 198: . 109271 A2 Review article, Literature review, Systematic review -
In Vivo Regulation of Signal Transduction Pathways by Vitamin D Stabilizes Homeostasis of Human Immune Cells and Counteracts Molecular Stress
Jaroslawska, Julia; Carlberg, Carsten. 2023. International journal of molecular sciences. 24: A1 Journal article (refereed), original research -
Intervention Approaches in Studying the Response to Vitamin D3 Supplementation
Gospodarska, Emilia; Ghosh Dastidar, Ranjini; Carlberg, Carsten. 2023. Nutrients. 15: A2 Review article, Literature review, Systematic review -
Linking Mechanisms of Vitamin D Signaling with Multiple Sclerosis
Carlberg, Carsten; Mycko, Marcin P. 2023. Cells. 12: . 2391 A2 Review article, Literature review, Systematic review -
Molecular Medicine : How Science Works
Carlberg, Carsten; Velleuer, Eunike; Molnár, Ferdinand. 2023. . . Springer D5 Textbook, professional manual or guide -
Nursing students’ genomics literacy: Basis for genomics nursing education course development
Parviainen, Anndra; Ward, Linda D; Halkoaho, Arja; Laing, Bobbi; Maguire, Jane; Palovaara, Marjo; Mandysova, Petra; Bacungan, Gabriel; Mamungay, Jima J; Sund, Reijo; Mikkonen, Santtu; Carlberg, Carsten; Vehviläinen-Julkunen, Katri. 2023. Teaching and learning in nursing. 18: 6-11 A1 Journal article (refereed), original research -
Nutrigenomics and redox regulation: Concepts relating to the Special Issue on nutrigenomics
Klotz, Lars-Oliver; Carlberg, Carsten. 2023. Redox biology. 68: A2 Review article, Literature review, Systematic review -
Nutrigenomics in the context of evolution
Carlberg, Carsten. 2023. Redox biology. 62: A2 Review article, Literature review, Systematic review -
Vitamin D, chromatin, and epigenetics
Carlberg, Carsten. Teoksessa: Hewison, Martin; Bouillon, Roger; Giovannucci, Edward; Goltzman, David; Meyer, Mark; Welsh, JoEllen(toim.) , 2023. Feldman and Pike's Vitamin D: Volume One: Biochemistry, Physiology and Diagnostics. s. 229-239. Academic press A3 Book section, Chapters in research books -
Vitamin D: A master example of nutrigenomics
Carlberg, Carsten; Raczyk, Marianna; Zawrotna, Natalia. 2023. Redox biology. 62: . 102695 A2 Review article, Literature review, Systematic review -
A Pleiotropic Nuclear Hormone Labelled Hundred Years Ago Vitamin D
Carlberg, Carsten. 2022. Nutrients. 2023; 15: B1 Non-refereed journal articles -
A Single Oral Vitamin D3 Bolus Reduces Inflammatory Markers in Healthy Saudi Males
AlGhamdi, Shareefa A.; Enaibsi, Nusaibah N.; Alsufiani, Hadeil M.; Alshaibi, Huda F.; Khoja, Sawsan O.; Carlberg, Carsten. 2022. International journal of molecular sciences. 23: A1 Journal article (refereed), original research -
A Single Vitamin D3 Bolus Supplementation Improves Vitamin D Status and Reduces Proinflammatory Cytokines in Healthy Females
Alsufiani, Hadeil M.; AlGhamdi, Shareefa A.; AlShaibi, Huda F.; Khoja, Sawsan O.; Saif, Safa F.; Carlberg, Carsten. 2022. Nutrients. 14: A1 Journal article (refereed), original research -
An update on vitamin D signaling and cancer
Carlberg, Carsten; Muñoz, Alberto. 2022. Seminars in cancer biology. 79: 217-230 A2 Review article, Literature review, Systematic review -
Gene-Regulatory Potential of 25-Hydroxyvitamin D3 and D2
Hanel, Andrea; Veldhuizen, Cor; Carlberg, Carsten. 2022. Frontiers in nutrition. 9: . 910601 A1 Journal article (refereed), original research -
Linguistic Validation of Genomic Nursing Concept Inventory to Finnish Applying Mandysova’s Decision Tree Algorithm
Dumo, Anndra Margareth; Mandysova, Petra; Ward, Linda D.; Laing, Bobbi; Lim, Anecita Gigi; Palovaara, Marjo; Saunders, Hannele; Maguire, Jane; Carlberg, Carsten; Sund, Reijo; Vehviläinen-Julkunen, Katri. 2022. Journal of nursing measurement. 31: 1-18 A1 Journal article (refereed), original research -
Molecular Immunology: How Science Works
Carlberg, Carsten; Velleuer, Eunike. 2022. . . Springer D5 Textbook, professional manual or guide -
Nutrigenomik : Gene und unsere Ernährung
Carlberg, Carsten; Klotz, Lars-Oliver; Molnár, Ferdinand. 2022. . . Springer D5 Textbook, professional manual or guide -
Nutrition and epigenetic programming
Carlberg, Carsten; Velleuer, Eunike. 2022. Current opinion in clinical nutrition and metabolic care. [December 26, 2022, Publish Ahead of Print]: 1-7 A2 Review article, Literature review, Systematic review -
Time-Resolved Gene Expression Analysis Monitors the Regulation of Inflammatory Mediators and Attenuation of Adaptive Immune Response by Vitamin D
Hanel, Andrea; Carlberg, Carsten. 2022. International journal of molecular sciences. 23: A1 Journal article (refereed), original research -
Vitamin D and Its Target Genes
Carlberg, Carsten. 2022. Nutrients. 14: A2 Review article, Literature review, Systematic review -
Vitamin D and Pigmented Skin
Carlberg, Carsten. 2022. Nutrients. 14: B1 Non-refereed journal articles -
Vitamin D and the risk for cancer: A molecular analysis
Carlberg, Carsten; Velleuer, Eunike. 2022. Biochemical pharmacology. 196: A2 Review article, Literature review, Systematic review -
Vitamin D in the Context of Evolution
Carlberg, Carsten. 2022. Nutrients. 14: A2 Review article, Literature review, Systematic review -
A hierarchical regulatory network analysis of the vitamin D induced transcriptome reveals novel regulators and complete VDR dependency in monocytes
Warwick, Timothy; Schulz, Marcel H; Guenther, Stefan; Gilsbach, Ralf; Neme, Antonio; Carlberg, Carsten; Brandes, Ralf P; Seuter, Sabine. 2021. Scientific reports. 11: 6518 A1 Journal article (refereed), original research -
Cancer Biology: How Science Works
Carlberg, Carsten; Velleuver, Eunike. 2021. . . Springer Nature D5 Textbook, professional manual or guide -
Replacing Saturated Fat with Polyunsaturated Fat Modulates Peripheral Blood Mononuclear Cell Gene Expression and Pathways Related to Cardiovascular Disease Risk Using a Whole Transcriptome Approach
Larsen, Sunniva, V; Holven, Kirsten B; Christensen, Jacob J; Flatberg, Arnar; Rundblad, Amanda; Leder, Lena; Blomhoff, Rune; Telle-Hansen, Vibeke; Kolehmainen, Marjukka; Carlberg, Carsten; Myhrstad, Mari C; Thoresen, Magne; Ulven, Stine M. 2021. Molecular nutrition and food research. 65: 2100633 A1 Journal article (refereed), original research -
Transcriptome-Wide Profile of 25-Hydroxyvitamin D3 in Primary Immune Cells from Human Peripheral Blood
Hanel, Andrea; Bendik, Igor; Carlberg, Carsten. 2021. Nutrients. 13: 4100 A1 Journal article (refereed), original research -
Vitamin D Treatment Sequence Is Critical for Transcriptome Modulation of Immune Challenged Primary Human Cells
Malmberg, Henna-Riikka; Hanel, Andrea; Taipale, Mari; Heikkinen, Sami; Carlberg, Carsten. 2021. Frontiers in immunology. 12: 754056 A1 Journal article (refereed), original research -
Common and personal target genes of the micronutrient vitamin D in primary immune cells from human peripheral blood
Hanel, Andrea; Neme, Antonio; Malinen, Marjo; Hämäläinen, Emmi; Malmberg, Henna-Riikka; Etheve, Stéphane; Tuomainen, Tomi-Pekka; Virtanen, Jyrki K; Bendik, Igor; Carlberg, Carsten. 2020. Scientific reports. 10: 21051 A1 Journal article (refereed), original research -
Genome-wide effects of chromatin on vitamin D signaling
Hanel, Andrea; Malmberg, Henna-Riikka; Carlberg, Carsten. 2020. Journal of molecular endocrinology. 64: R45-R56 A2 Review article, Literature review, Systematic review -
Impact of Epigenetics on Complications of Fanconi Anemia: The Role of Vitamin D-Modulated Immunity
Velleuer, Eunike; Carlberg, Carsten. 2020. Nutrients. 12: 1355 A2 Review article, Literature review, Systematic review -
Key Vitamin D Target Genes With Functions in the Immune System
Koivisto, Oona; Hanel, Andrea; Carlberg, Carsten. 2020. Nutrients. 12: 1140 A1 Journal article (refereed), original research -
Mechanisms of Gene Regulation: How Science works
Carlberg, Carsten; Molnár, Ferdinand. 2020. . . Springer Nature D5 Textbook, professional manual or guide -
Monitoring genome-wide chromatin accessibility by formaldehyde-assisted isolation of regulatory elements sequencing (FAIRE-seq)
Seuter, Sabine; Neme, Antonio; Carlberg, Carsten. Teoksessa: Tollefsbol, Trygve(toim.) , 2020. Epigenetics Methods. s. 353-369. Elsevier A3 Book section, Chapters in research books -
Nutrigenomics: How Science works
Carlberg, Carsten; Ulven, Stine Marie; Molnár, Ferdinand. 2020. . . Springer D5 Textbook, professional manual or guide -
Randomized controlled trial on the effectiveness of web-based Genomics Nursing Education Intervention for undergraduate nursing students: a study protocol
Dumo, AM; Laing, B; Lim, AG; Palaganas, E; Abad, PJ; Valdehueza, O; Palovaara, M; Saunders, H; Estola, M; Mandysova, P; Maguire, J; Ward, LD; Carlberg, C; Vehviläinen-Julkunen, K. 2020. Journal of advanced nursing. 76: 3136-3146 A1 Journal article (refereed), original research -
Skin Color and Vitamin D: An Update
Hanel, Andrea; Carlberg, Carsten. 2020. Experimental dermatology. 29: 864-875 A2 Review article, Literature review, Systematic review -
Vitamin D and evolution: pharmacologic implications
Hanel, Andrea; Carlberg, Carsten. 2020. Biochemical pharmacology. 173: 113595 A2 Review article, Literature review, Systematic review -
Vitamin D receptor(s): in the nucleus but also at membranes?
Zmijewski, MA; Carlberg, C. 2020. Experimental dermatology. 29: 876-884 A1 Journal article (refereed), original research -
An Isocaloric Nordic Diet Modulates RELA and TNFRSF1A Gene Expression in Peripheral Blood Mononuclear Cells in Individuals with Metabolic Syndrome-A SYSDIET Sub-Study
Ulven, SM; Holven, KB; Rundblad, A; Myhrstad, MCW; Leder, L; Dahlman, I; Mello, VD; Schwab, U; Carlberg, C; Pihlajamäki, J; Hermansen, K; Dragsted, LO; Gunnarsdottir, I; Cloetens, L; Åkesson, B; Rosqvist, F; Hukkanen, J; Herzig, KH; Savolainen, MJ; Risérus, U; et al. [incl. Uusitupa, M]. 2019. Nutrients. 11: 2932 A1 Journal article (refereed), original research -
Healthy Nordic Diet Modulates the Expression of Genes Related to Mitochondrial Function and Immune Response in Peripheral Blood Mononuclear Cells from Subjects with the Metabolic Syndrome - A SYSDIET Sub-Study
Myhrstad, MC; de Mello, VD; Dahlman, I; Kolehmainen, M; Paananen, J; Rundblad, A; Carlberg, C; Olstad, OK; Pihlajamäki, J; Holven, KB; Hermansen, K; Dragsted, LO; Gunnarsdottir, I; Cloetens, L; Storm, MU; Åkesson, B; Rosqvist, F; Hukkanen, J; et al. (incl. Schwab, U; Uusitupa, M). 2019. Molecular nutrition and food research. 63: 1801405 A1 Journal article (refereed), original research -
Highlights from the 21st Workshop on Vitamin D in Barcelona, May 2018
Fleet, JC; Campbell, MJ; Carlberg, C; Demay, MB; Ebeling, PR; Schoenmakers, I; White, JH; Welsh, J; Hewison, M. 2019. Journal of steroid biochemistry and molecular biology. 189: 210-217 B1 Non-refereed journal articles -
In vivo transcriptome changes of human white blood cells in response to vitamin D
Neme, Antonio; Seuter, Sabine; Malinen, Marjo; Nurmi, Tarja; Tuomainen, Tomi-Pekka; Virtanen, Jyrki K; Carlberg, Carsten. 2019. Journal of steroid biochemistry and molecular biology. 188: 71-76 A1 Journal article (refereed), original research -
Nutrigenomics of Vitamin D
Carlberg, Carsten. 2019. Nutrients. 11: 676 A2 Review article, Literature review, Systematic review -
Primary Vitamin D Target Genes of Human Monocytes
Nurminen, V; Seuter, S; Carlberg, C. 2019. Frontiers in physiology. 10: 194 A2 Review article, Literature review, Systematic review -
Vitamin D Signaling Suppresses Early Prostate Carcinogenesis in TgAPT121 Mice
Fleet, JC; Kovalenko, PL; Li, Y; Smolinski, J; Spees, C; Yu, JG; Thomas-Ahner, JM; Cui, M; Neme, A; Carlberg, C; Clinton, SK. 2019. Cancer prevention research. 12: 343-356 A1 Journal article (refereed), original research -
Vitamin D Signaling in the Context of Innate Immunity: Focus on Human Monocytes
Carlberg, Carsten. 2019. Frontiers in immunology. 10: 2211 A2 Review article, Literature review, Systematic review -
Vitamin D and Its Synthetic Analogs
Maestro, Miguel A; Molnár, Ferdinand; Carlberg, Carsten. 2019. Journal of medicinal chemistry. 62: 6854-6875 A1 Journal article (refereed), original research -
Vitamin D: A Micronutrient Regulating Genes
Carlberg, Carsten. 2019. Current pharmaceutical design. 25: 1740-1746 A2 Review article, Literature review, Systematic review -
A Machine learning approaches infer vitamin D signaling: Critical impact of vitamin D receptor binding within topologically associated domains
Carlberg, Carsten; Neme, Antonio. 2018. Journal of steroid biochemistry and molecular biology. 2019; 15: 103-109 A2 Review article, Literature review, Systematic review -
ETS transcription factor family member GABPA contributes to vitamin D receptor target gene regulation
Seuter, Sabine; Neme, Antonie; Carlberg, Carsten. 2018. Journal of steroid biochemistry and molecular biology. 177: 46-52 A1 Journal article (refereed), original research -
Highlights from the 6th International Conference on Vitamin D Deficiency, "Nutrition and Human Health", Abu Dhabi, United Arab Emirates, March 9-10, 2017
Haq, Afrozul; Wimalawansa, Sunil J; Carlberg, Carsten. 2018. Journal of steroid biochemistry and molecular biology. 180: 1-3 B1 Non-refereed journal articles -
Human Epigenomics
Carlberg, Carsten; Molnár, Ferdinand. 2018. . . Springer D5 Textbook, professional manual or guide -
In vivo response of the human epigenome to vitamin D: A proof-of-principle study
Carlberg, Carsten; Seuter, Sabine; Nurmi, Tarja; Tuomainen, Tomi-Pekka; Virtanen, Jyrki K; Neme, Antonio. 2018. Journal of steroid biochemistry and molecular biology. 180: 142-148 A1 Journal article (refereed), original research -
Modulation of vitamin D signaling by the pioneer factor CEBPA
Nurminen, Veijo; Neme, Antonio; Seuter, Sabine; Carlberg, Carsten. 2018. Biochimica et biophysica acta: gene regulatory mechanisms. 2019; 1862: 96-106 A1 Journal article (refereed), original research -
The impact of the vitamin D-modulated epigenome on VDR target gene regulation
Nurminen, Veijo; Neme, Antonio; Seuter, Sabine; Carlberg, Carsten. 2018. Biochimica et biophysica acta: gene regulatory mechanisms. 1861: 697-705 A1 Journal article (refereed), original research -
Vitamin D
Carlberg, Carsten. Teoksessa: Maccarrone, Mauro; Clarke, Angus; Zheng, Yixian; Tickle, Cheryll; Kehrer-Sawatzki, Hildegard; Cooper, David N; Delves, Peter; Pettis, Gregg; Candi, Eleonora; Perkel, David J; Hetherington, Alistair M; Bynum, William F; Valpuesta, José María; Harper, David(toim.) , 2018. Encyclopedia of Life Sciences (eLS). s. -. John Wiley & Sons A3 Book section, Chapters in research books -
Vitamin D Genomics: From In Vitro to In Vivo
Carlberg, Carsten. 2018. Frontiers in endocrinology. 9: 250 A1 Journal article (refereed), original research -
Endocrine functions of vitamin D
Carlberg Carsten. 2017. Molecular and cellular endocrinology. 453: 1-2 B1 Non-refereed journal articles -
Epigenomic PU.1-VDR crosstalk modulates vitamin D signaling
Seuter S, Neme A, Carlberg C. 2017. Biochimica et biophysica acta: gene regulatory mechanisms. 1860: 405-415 A1 Journal article (refereed), original research -
Highlights from the 5th International Conference on Vitamin D Deficiency, Nutrition and Human Health, Abu Dhabi, United Arab Emirates, March 24-25, 2016
Haq A, Wimalawansa SJ, Carlberg C. 2017. Journal of steroid biochemistry and molecular biology. 175: 1-3 B1 Non-refereed journal articles -
Integration of VDR genome wide binding and GWAS genetic variation data reveals co-occurrence of VDR and NF-kappaB binding that is linked to immune phenotypes
Singh PK, van den Berg PR, Long MD, Vreugdenhil A, Grieshober L, Ochs-Balcom HM, Wang J, Delcambre S, Heikkinen S, Carlberg C, Campbell MJ, Sucheston-Campbell LE. 2017. Bmc genomics. 18: - A1 Journal article (refereed), original research -
Molecular endocrinology of vitamin D on the epigenome level
Carlberg Carsten. 2017. Molecular and cellular endocrinology. 453: 14-21 A1 Journal article (refereed), original research -
Molecular evaluation of vitamin D responsiveness of healthy young adults
Seuter Sabine, Virtanen Jyrki K, Nurmi Tarja, Pihlajamäki Jussi, Mursu Jaakko, Voutilainen Sari, Tuomainen Tomi-Pekka, Neme Antonio, Carlberg Carsten. 2017. Journal of steroid biochemistry and molecular biology. 174: 314-321 A1 Journal article (refereed), original research -
Selective regulation of biological processes by vitamin D based on the spatio-temporal cistrome of its receptor
Neme Antonio, Seuter Sabine, Carlberg Carsten. 2017. Biochimica et biophysica acta: gene regulatory mechanisms. 1860: 952-961 A1 Journal article (refereed), original research -
The concept of the personal vitamin D response index
Carlberg Carsten, Haq Afrozul. 2017. Journal of steroid biochemistry and molecular biology. 2018; 175: 12-17 A2 Review article, Literature review, Systematic review -
Vitamin D and chromatin
Carlberg Carsten. Teoksessa: Feldman David, Pike J Wesley, Bouillon Roger, Giovannucci Edward, Goltzman David, Hewison Martin(toim.) , 2017. Vitamin D. 4th Edition. Volume 1: Biochemistry, Physiology and Diagnostics. s. 217-226. Elsevier A3 Book section, Chapters in research books -
Effects of a healthy Nordic diet on gene expression changes in peripheral blood mononuclear cells in response to an oral glucose tolerance test in subjects with metabolic syndrome: a SYSDIET sub-study
Leder Lena, Kolehmainen Marjukka, Narverud Ingunn, Dahlman Ingrid, Myhrstad Mari CW, de Mello Vanessa D, Paananen Jussi, Carlberg Castren, Schwab Ursula, Herzig Karl-Heinz, Cloetens Lieselotte, Storm Matilda Ulmius, Hukkanen Janne, Savolainen Markku J, Rosqvist Fredrik, Hermansen Kjeld, Dragsted Lars O, Gunnarsdottir Ingibjörk, Thorsdottir Inga, Risérus Ulf et al.. 2016. Genes and nutrition. 11: 1-13 A1 Journal article (refereed), original research -
Mechanisms of gene regulation (2. ed)
Carlberg Carsten, Molnár Ferdinand. 2016. . 2nd ed. Springer C1 Book -
Nutrigenomics
Carlberg Carsten, Ulven Stine Marie, Molnár Ferdinand. 2016. . . Springer C1 Book -
Vitamin D
Carlberg Carsten. Teoksessa: Caplan Michael(toim.) , 2016. Reference Module in Biomedical Sciences. s. -. Elsevier A3 Book section, Chapters in research books -
Vitamin D receptor 2016: novel ligands and structural insights
Maestro Miguel A, Molnár Ferdinand, Mouriño Antonio, Carlberg Carsten. 2016. Expert opinion on therapeutic patents. 26: 1291-1306 A2 Review article, Literature review, Systematic review -
Vitamin D receptor signaling improves Hutchinson-Gilford progeria syndrome cellular phenotypes
Kreienkamp Ray, Croke Monica, Neumann Martin A, Bedia-Diaz Gonzalo, Graziano Simona, Dusso Adriana, Dorsett Dale, Carlberg Carsten, Gonzalo Susana. 2016. Oncotarget. 7: 30018-30031 A1 Journal article (refereed), original research -
Vitamin D-dependent chromatin association of CTCF in human monocytes
Neme Antonio, Seuter Sabine, Carlberg Carsten. 2016. Biochimica et biophysica acta: gene regulatory mechanisms. 1859: 1380-1388 A1 Journal article (refereed), original research -
Epigenome-wide effects of vitamin D and their impact on the transcriptome of human monocytes involve CTCF
Seuter Sabine, Neme Antonio, Carlberg Carsten. 2015. Nucleic acids research. 2016; 44: 4090-4104 A1 Journal article (refereed), original research -
Molecular approaches for optimizing vitamin D supplementation
Carlberg Carsten. 2015. Vitamins and hormones series. 2016; 100: 255-271 A1 Journal article (refereed), original research -
Multiplex Eukaryotic Transcription (In) activation: Timing, Bursting and Cycling of a Ratchet Clock Mechanism
Rybakova Katja N, Bruggeman Frank J, Tomaszewska Aleksandra, Moné Martijn J, Carlberg Carsten, Westerfoff Hans V. 2015. PLoS computational biology. 11: e1004236 A1 Journal article (refereed), original research -
Relevance of Vitamin D Receptor Target Genes for Monitoring the Vitamin D Responsiveness of Primary Human Cells
Vukic Maja, Neme Antonio, Seuter Sabine, Saksa Noora, de Mello Vanessa DF, Nurmi Tarja, Uusitupa Matti, Tuomainen Tomi-Pekka, Virtanen Jyrki K, Carlberg Carsten. 2015. PLoS ONE. 10: e0124339 A1 Journal article (refereed), original research -
The vitamin D-dependent transcriptome of human monocytes
Neme Antonio, Nurminen Veijo, Seuter Sabine, Carlberg Carsten. 2015. Journal of steroid biochemistry and molecular biology. 2016; 164: 180-187 A2 Review article, Literature review, Systematic review -
Vitamin D receptor signaling and its therapeutic implications: Genome-wide and structural view
Carlberg Carsten, Molnár Ferdinand. 2015. Canadian journal of physiology and pharmacology. 93: 311-318 A2 Review article, Literature review, Systematic review -
Changes in vitamin D target gene expression in adipose tissue monitor the vitamin D response of human individuals
Ryynänen Jussi, Neme Antonio, Tuomainen Tomi-Pekka, Virtanen Jyrki K, Voutilainen Sari, Nurmi Tarja, de Mello Vanessa DF, Uusitupa Matti, Carlberg Carsten. 2014. Molecular nutrition and food research. 58: 2036-2045 A1 Journal article (refereed), original research -
Characterization of genomic vitamin D receptor binding sites through chromatin looping and opening
Seuter Sabine, Neme Antonio, Carlberg Carsten. 2014. PLoS ONE. 9: e96184 A1 Journal article (refereed), original research -
Dissecting high from low responders in a vitamin D3 intervention study
Saksa Noora, Neme Antonio, Ryynänen Jussi, Uusitupa Matti, de Mello Vanessa DF, Voutilainen Sari, Nurmi Tarja, Virtanen Jyrki K, Tuomainen Tomi-Pekka, Carlberg Carsten. 2014. Journal of steroid biochemistry and molecular biology. Epub ahead of print: - A1 Journal article (refereed), original research -
Effects of a healthy Nordic diet on plasma 25-hydroxyvitamin D concentration in subjects with metabolic syndrome: a randomized, placebo-controlled trial (SYSDIET)
Brader Lea, Rejnmark Lars, Carlberg Carsten, Schwab Ursula, Kolehmainen Marjukka, Rosqvist Fredrik, Cloetens Lieselotte, Landin-Olsson Mona, Gunnarsdottir Ingibjorg, Poutanen Kaisa S, Herzig Karl-Heinz, Risérus Ulf, Savolainen Markku J, Thorsdottir Inga, Uusitupa Matti, Hermansen Kjeld. 2014. European journal of nutrition. 53: 1123-34 A1 Journal article (refereed), original research -
From pharmacogenomics to integrated personal omics profiling: a gap in implementation into healthcare
Carlberg Carsten, Raunio Hannu. 2014. Personalized medicine. 11: 625-629 A1 Journal article (refereed), original research -
Genome-wide (over)view on the actions of vitamin D
Carlberg Carsten. 2014. Frontiers in physiology. 5: 1-10 A2 Review article, Literature review, Systematic review -
Healthy Nordic diet downregulates the expression of genes involved in inflammation in subcutaneous adipose tissue in individuals with features of the metabolic syndrome
Kolehmainen Marjukka, Ulven Stine M, Paananen Jussi, de Mello Vanessa, Schwab Ursula, Carlberg Carsten, Myhrstad Mari, Pihlajamäki Jussi, Dungner Elisabeth, Sjölin Eva, Gunnarsdottir Ingibjörg, Cloetens Lieselotte, Landin-Olsson Mona, Akesson Björn, Rosqvist Fredrik, Hukkanen Janne, Herzig Karl-Heinz, Dragsted Lars O, Savolainen Markku J, Brader Lea, Hermansen Kjeld, Risérus Ulf, Thorsdottir Inga, Poutanen Kaisa S, Uusitupa Matti, Arner Peter, Dahlman Ingrid. 2014. American journal of clinical nutrition. 101: 228-239 A1 Journal article (refereed), original research -
Mechanisms of Gene Regulation
Carlberg Carsten, Molnár Ferdinand. 2014. . . Springer C1 Book -
Patterns of Genome-Wide VDR Locations
Tuoresmäki Pauli, Väisänen Sami, Neme Antonio, Heikkinen Sami, Carlberg Carsten. 2014. PLoS ONE. 9: e96105 A1 Journal article (refereed), original research -
Primary vitamin D receptor target genes as biomarkers for the vitamin D3 status in the hematopoietic system
Wilfinger Julia, Seuter Sabine, Tuomainen Tomi-Pekka, Virtanen Jyrki K, Voutilainen Sari, Nurmi Tarja, de Mello Vanessa DF, Uusitupa Matti, Carlberg Carsten. 2014. Journal of nutritional biochemistry. 25: 875-884 A1 Journal article (refereed), original research -
The physiology of vitamin D - far more than calcium and bone
Carlberg Carsten. 2014. Frontiers in physiology. 5: - A1 Journal article (refereed), original research -
The transcriptional regulator BCL6 participates in the secondary gene regulatory response to vitamin D
Nurminen Veijo, Neme Antonio, Ryynänen Jussi, Heikkinen Sami, Seuter Sabine, Carlberg Carsten. 2014. Biochimica et biophysica acta: gene regulatory mechanisms. Epub ahead of print: - A1 Journal article (refereed), original research -
Tracing the molecular basis of transcriptional dynamics in noisy data by using an experiment-based mathematical model
Rybakova Katja N, Tomaszewska Aleksandra, van Mourik Simon, Blom Joke, Westerhoff Hans V, Carlberg Carsten, Bruggeman Frank J. 2014. Nucleic acids research. Epub ahead of print: - A1 Journal article (refereed), original research -
What Do We Learn from the Genome-wide Perspective on Vitamin D3?
Carlberg Carsten. 2014. Anticancer research. 48: 217-218 A2 Review article, Literature review, Systematic review -
Dynamics of 1α ,25-dihydroxyvitamin D3-dependent chromatin accessibility of early vitamin D receptor target genes
Seuter S, Pehkonen P, Heikkinen S, Carlberg C. 2013. Biochimica et biophysica acta: international journal of biochemistry and biophysics. 1829: 1266-1275 A1 Journal article (refereed), original research -
Gene Regulatory Scenarios of Primary 1,25-Dihydroxyvitamin D3 Target Genes in a Human Myeloid Leukemia Cell Line
Ryynänen J, Seuter S, Campbell MJ, Carlberg C. 2013. Cancers. 5: 1221-1241 A1 Journal article (refereed), original research -
Primary 1,25-Dihydroxyvitamin D3 Response of the Interleukin 8 Gene Cluster in Human Monocyte- and Macrophage-Like Cells
Ryynänen J, Carlberg C. 2013. PLoS ONE. 8: e78170 A1 Journal article (refereed), original research -
Primary vitamin D target genes allow a categorization of possible benefits of vitamin D3 supplementation
Carlberg C, Seuter S, de Mello VDF, Schwab U, Voutilainen S, Pulkki K, Nurmi T, Virtanen J, Tuomainen T-P, Uusitupa M. 2013. PLoS ONE. 8: e71042 A1 Journal article (refereed), original research -
The ASAP2 gene is a primary target of 1,25-dihydroxyvitamin D3 in human monocytes and macrophages
Seuter S, Ryynänen J, Carlberg C. 2013. Journal of steroid biochemistry and molecular biology. [Epub ahead of print]: x-x A1 Journal article (refereed), original research -
Vitamin D receptor signaling mechanisms: Integrated actions of a well-defined transcription factor
Carlberg C, Campbell MJ. 2013. Steroids. 78: 127-136 A1 Journal article (refereed), original research -
Chromatin acetylation at transcription start sites and vitamin D receptor binding regions relates to effects of 1alfa,25-dihydroxyvitamin D3 and histone deacetylase inhibitors on gene expression
Seuter S, Heikkinen S, Carlberg C. 2012. Nucleic acids research. -: - A1 Journal article (refereed), original research -
Current status of vitamin D signaling and its therapeutic applications
Carlberg Carsten, Molnár Ferdinand. 2012. Current topics in medicinal chemistry. 12: 528-547 A1 Journal article (refereed), original research -
Dataset integration identifies transcriptional regulation of microRNA genes by PPARgamma in differentiating mouse 3T3-L1 adipocytes
John E, Wienecke-Baldacchino A, Liivrand M, Heinäniemi M, Carlberg C, Sinkkonen L. 2012. Nucleic acids research. 40: 4446-4460 A1 Journal article (refereed), original research -
Differential effects of 1alfa,25-dihydroxycholecalciferol on MCP-1 and adiponectin production in human white adipocytes
Lorente-Cebrián S, Eriksson A, Dunlop T, Mejhert N, Dahlman I, Åström G, Sjölin E, Wåhlén K, Carlberg C, Laurencikiene J, Hedén P, Arner P, Rydén M. 2012. European journal of nutrition. 51: 335-342 A1 Journal article (refereed), original research -
Genome-wide landscape of liver X receptor chromatin binding and gene regulation in human macrophages
Pehkonen P, Welter-Stahl L, Diwo J, Ryynänen J, Wienecke-Baldacchino A, Heikkinen S, Treuter E, Steffensen K, Carlberg C. 2012. Bmc genomics. 13: - A1 Journal article (refereed), original research -
Inhibition of cytokine secretion from adipocytes by 1,25-dihydroxyvitamin D3 via the NF-kappaB pathway
Mutt SJ, Karhu T, Lehtonen S, Lehenkari P, Carlberg C, Saarnio J, Sebert S, Hyppönen E, Järvelin M-R, Herzig K-H. 2012. Faseb journal. 26: 4400-4407 A1 Journal article (refereed), original research -
The First Genome-wide View of Vitamin D Receptor Locations and Their Mechanistic Implications
Carlberg C, Seuter S, Heikkinen S. 2012. Anticancer research. 32: 271-282 A2 Review article, Literature review, Systematic review -
The gene for the transcription factor BHLHE40/DEC1/stra13 is a dynamically regulated primary target of the vitamin D receptor
Seuter S, Pehkonen P, Heikkinen S, Carlberg C. 2012. Journal of steroid biochemistry and molecular biology. online: - A1 Journal article (refereed), original research -
The need for education in personalized medicine
Carlberg C. 2012. Personalized medicine. 9: 147-150 A2 Review article, Literature review, Systematic review -
Vitamin D receptor ligands: the impact of crystal structures
Carlberg Carsten, Molnár Ferdinand, Mouriño Antonio. 2012. Expert opinion on therapeutic patents. 22: 417-435 A2 Review article, Literature review, Systematic review -
1,25-Dihydroxyvitamin D(3) Influences Cellular Homocystine Levels in Murine Preosteoplastic MC3T3-E1 Cells by Directs Regulation of Cystathionine beta-Synthase
Kriebitzsch C, Verlinden L, Eelen G, van Schoor NM, Swart K, Lips P, Meyer MB, Pike JW, Boonen S, Carlberg C, Vitvitsky V, Bouillon R, Banerjee R, Verstuyf A. 2011. Journal of bone and mineral research. 26: 2991-2000 A1 Journal article (refereed), original research -
Cyclical regulation of the insulin-like growth factor binding protein 3 gene in response to 1alpha,25-dihydroxyvitamin D3
Malinen Marjo, Ryynänen Jussi, Heinniemi Merja, Sami Väisänen Sami, Carlberg Carsten. 2011. Nucleic acids research. 39: 502-512 A1 Journal article (refereed), original research -
Dynamic nature of transcriptional regulation of nuclear receptor target genes in the context of chromatin organization
Väisänen Sami, Matilainen Juha, Carlberg Carsten. 2011. Dermato-endocrinology. 3: 1-5 A2 Review article, Literature review, Systematic review -
Electrophilic nitro-fatty acids activate NRF2 by a KEAP1 cysteine 151-independent mechanism
Kansanen Emilia, Bonacci Gustavo, Schopfer Francisco J, Kuosmanen Suvi M, Tong Kit I, Leinonen Hanna, Woodcock Steven R, Yamamoto Masayuk, Carlberg Carsten, Ylä-Herttuala Seppo, Freeman Bruce A, Levonen Anna-Liisa. 2011. Journal of biological chemistry. 286: 14019-14027 A1 Journal article (refereed), original research -
Mechanism of 1α ,25-dihydroxyvitamin D3-dependent repression of interleukin-12B
Gynther Petra, Toropainen Sari, Matilainen Juha M, Seuter Sabine, Carlberg Carsten, Väisänen Sami. 2011. Biochimica et biophysica acta: molecular cell research. 1813: 810-818 A1 Journal article (refereed), original research -
Nuclear hormone 1α ,25-dihydroxyvitamin D3 elicits a genome-wide shift in the locations of VDR chromatin occupancy
Heikkinen Sami, Väisänen Sami, Pehkonen Petri, Seuter Sabine, Benes Vladimir, Carlberg Carsten. 2011. Nucleic acids research. 39: 9181-9193 A1 Journal article (refereed), original research -
25-Hydroxyvitamin D3 is an Agonistic Vitamin D Receptor Ligand
Lou, Y-R., Molnár, F., Peräkylä, M., Qiao, S., Kalueff, A.V., St-Arnaud, R., Carlberg, C. and Tuohimaa, P.. 2010. Journal of steroid biochemistry and molecular biology. 118: 162-170 A1 Journal article (refereed), original research -
The Down-regulation of the Human MYC Gene by the Nuclear Hormone 1α ,25-dihydroxyvitamin D3 is Associated with Cycling of Corepressors and Histone Deacetylases
Sari Toropainen, Sami Väisänen, Sami Heikkinen,Carsten Carlberg. 2010. Journal of molecular biology. 400: 284-294 A1 Journal article (refereed), original research -
A genomic perspective on vitamin D signaling
Carlberg C, Seuter S. 2009. Anticancer research. 29: 3485-3494 A2 Review article, Literature review, Systematic review -
Cell cycle regulatory effects of retinoid acid and forskolin are mediated by the Cyclin C gene
Makkonen KM, Malinen M, Ropponen A, Väisänen S, Carlberg C. 2009. Journal of molecular biology. 393: 261-271 A1 Journal article (refereed), original research -
Cyclical chromatin looping and transcription factor association on the regulatory regions of the p21 (CDKN1A) gene in response to 1[alpha],25-dihydroxyvitamin D3
Saramäki A, Diermeier S, Kellner R, Laitinen H, Väisänen S, Carlberg C. 2009. Journal of biological chemistry. 284: 8073-8082 A1 Journal article (refereed), original research -
Peroxisome proliferator-activated receptor [alpha] controls hepatic heme biosynthesis throught ALAS1
Degenhardt T, Väisänen S, Rakhshandehroo M, Kersten S, Carlberg C. 2009. Journal of molecular biology. 388: 225-238 A1 Journal article (refereed), original research -
Population-level transcription cycles derive from stochastic timing of single-cell transcription
Degenhardt T, Rybakova KN, Tomaszewska A, Moné MJ, Westerhoff HV, Bruggeman FJ, Carlberg C. 2009. Cell. 138: 489-501 A1 Journal article (refereed), original research -
Regulation of the hyaluronan synthase 2 gene by convergence in cyclic AMP response element-binding protein and retinoid acid receptor signaling
Makkonen KM, Pasonen-Seppänen S, Törrönen K, Tammi MI, Carlberg C. 2009. Journal of biological chemistry. 284: 18270-18281 A1 Journal article (refereed), original research -
A role for the PPARgamma in cancer therapy
Campbell MJ, Carlberg C, Koeffler HP. 2008. Ppar research. : 17 s A2 Review article, Literature review, Systematic review -
DICKKOPF-4 is induced by TCF/beta-catenin and upregulated in human colon cancer, promotes tumour cell invasion and angiogenesis and is repressed by 1alpha,25-dihydroxyvitamin D3
Pendás-Franco N, García JM, Peña C, Valle N, Pálmer HG, Heinäniemi M, Carlberg C, Jiménez B, Bonilla F, Muñoz A, González-Sancho JM. 2008. Oncogene. 27: 4467-4477 A1 Journal article (refereed), original research -
Distinct HDACs regulate the transcriptional response of human cyclin-dependent kinase inhibitor genes to trichostatin A and 1alpha,25-dihydroxyvitamin D3
Malinen M, Saramäki A, Ropponen A, Degenhardt T, Väisänen S, Carlberg C. 2008. Nucleic acids research. 36: 121-132 A1 Journal article (refereed), original research -
Screening for PPAR responsive regulatory modules in cancer
Heinäniemi M, Carlberg C. 2008. Ppar research. 2008: 8 s A2 Review article, Literature review, Systematic review -
Variations in the ghrelin receptor gene associate with obesity and glucose metabolism in individuals with impaired glucose tolerance
Mager U, Degenhardt T, Pulkkinen L, Kolehmainen M, Tolppanen A-M, Lindström J, Eriksson JG, Carlberg, Tuomilehto J, Uusitupa M, for the Finnish Diabetes Prevention Study Group. 2008. PLoS ONE. 3: e2941 A1 Journal article (refereed), original research -
Controlling the chromatin organization of vitamin D target genes by multiple vitamin D receptor binding sites
Carlberg C, Dunlop TW, Saramäki A, Sinkkonen L, Matilainen M, Väisänen S. 2007. Journal of steroid biochemistry and molecular biology. : 338-343 A1 Journal article (refereed), original research -
Functional characterization of vitamin D responding regions in the human 5-lipoxygenase gene
Seuter S, Väisänen S, Rådmark O, Carlberg C, Steinhilber D. 2007. Biochimica et biophysica acta: international journal of biochemistry and biophysics. 1771: 864-872 A1 Journal article (refereed), original research -
Integration of the activation of the human hyaluronan synthase 2 gene promoter by common cofactors of the transcription factors retinoic acid receptor and nuclear factor kappaB
Saavalainen K, Tammi MI, Bowen T, Lienhard Schmitz M, Carlberg C. 2007. Journal of biological chemistry. 282: 11530-11539 A1 Journal article (refereed), original research -
Meta-analysis of primary target genes of peroxisome proliferator-activated receptors
Heinäniemi M, Uski JO, Degenhardt T, Carlberg C. 2007. Genome biology. 8: R147 A1 Journal article (refereed), original research -
Selective use of multiple vitamin D response elements underlies the 1alpha,25-dihydroxyvitamin D3-mediated negative regulation of the human CYP27B1 gene
Turunen MM, Dunlop TW, Carlberg C, Väisänen S. 2007. Nucleic acids research. 35: 2734-2747 A1 Journal article (refereed), original research -
Subcellular localisation of BAG-1 and its regulation of vitamin D receptor-mediated transactivation and involucrin expression in oral keratinocytes: implications for oral carcinogenesis
Lee SS, Crabb SJ, Janghra N, Carlberg C, Williams AC, Cutress RI, Packham G, Hague A. 2007. Experimental cell research. 313: 3222-3238 A1 Journal article (refereed), original research -
The vitamin D receptor
Carlberg C, Seuter S. 2007. Dermatologic clinics. 25: 515-523 A1 Journal article (refereed), original research -
Three members of the human pyruvate dehydrogenase kinase gene family are direct targets of the peroxisome proliferator-activated receptor beta/delta
Degenhardt T, Saramäki A, Malinen M, Rieck M, Väisänen S, Huotari A, Herzig K-H, Müller R, Carlberg C. 2007. Journal of molecular biology. 372: 341-355 A1 Journal article (refereed), original research -
Vitamins as hormones
Reichrath J, Lehmann B, Carlberg C, Varani J, Zouboulis CC. 2007. Hormone and metabolic research. 39: 71-84 A2 Review article, Literature review, Systematic review -
An integrated biological approach to nuclear receptor signaling in physiological control and disease
Carlberg C, Dunlop TW. 2006. Critical reviews in eukaryotic gene expression. 16: 1-22 A1 Journal article (refereed), original research -
Analysis of the 5-lipoxygenase promoter and characterization of a vitamin D receptor binding site
Sorg BL, Klan N, Seuter S, Dishart D, Rådmark O, Habenicht A, Carlberg C, Werz O, Steinhilber D. 2006. Biochimica et biophysica acta: international journal of biochemistry and biophysics. 1761: 686-697 A1 Journal article (refereed), original research -
Detailed molecular understanding of agonistic and antagonistic vitamin D receptor ligands
Carlberg C, Molnar F. 2006. Current topics in medicinal chemistry. 6: 1243-53 A1 Journal article (refereed), original research -
Epigenetic corruption of VDR signalling in malignancy
Abedin SA, Banwell CM, Colston KW, Carlberg C, Campbell MJ. 2006. Anticancer research. 26: 2557-2566 A2 Review article, Literature review, Systematic review -
Regulation of the human p21(waf1/cip1) gene promoter via multiple binding sites for p53 and the vitamin D3 receptor
Saramäki A, Banwell CM, Campbell MJ, Carlberg C. 2006. Nucleic acids research. 34: 543-554 A1 Journal article (refereed), original research -
The impact of chromatin organization of vitamin D target genes
Carlberg C, Dunlop TW. 2006. Anticancer research. 26: 2637-2646 A2 Review article, Literature review, Systematic review -
The insulin-like growth factor-binding protein 1 gene is a primary target of peroxisome proliferator-activated receptors
Degenhardt T, Matilainen M, Herzig K-H, Dunlop TW, Carlberg C. 2006. Journal of biological chemistry. 281: 39607-39619 A1 Journal article (refereed), original research -
Vitamin D receptor agonists specifically modulate the volume of the ligand-binding pocket
Molnár F, Peräkylä M, Carlberg C. 2006. Journal of biological chemistry. 281: 10516-10526 A1 Journal article (refereed), original research -
A role of melatonin in neuroectodermal-mesodermal interactions: the hair follicle synthesizes melatonin and expresses functional melatonin receptors
Kobayashi H, Kromminga A, Dunlop TW, Tychsen B, Conrad F, Suzuki N, Memezava A, Bettermann A, Aiba S, Carlberg C, Paus R. 2005. Faseb journal. 19: 1710-1712 A1 Journal article (refereed), original research -
Antagonist- and inverse agonist-driven interactions of the vitamin D receptor and the constitutive androstane receptor with corepressor protein
Lempiäinen H, Molnár F, Macias Gonzalez M, Peräkylä M, Carlberg C. 2005. Molecular endocrinology. 19: 2258-2272 A1 Journal article (refereed), original research -
Gene regulatory potential of nonsteroidal vitamin D receptor ligands
Peräkylä M, Malinen M, Herzig K-H, Carlberg C. 2005. Molecular endocrinology. 19: 2060-2073 A1 Journal article (refereed), original research -
Identification of pregnane X reseptor binding sites in the regulatory regions of genes involved in bile acid homeostasis
Frank C, Makkonen H, Dunlop TW, Matilainen M, Väisänen S, Carlberg C. 2005. Journal of molecular biology. 346: 506-519 A1 Journal article (refereed), original research -
Molecular basis of the diversity of vitamin D target genes
Carlberg C, Dunlop TW, Frank C, Väisänen S. Teoksessa: Feldman D, Wesley Pike J, Glorieux FH(toim.) , 2005. Vitamin D. s. 313-325. Elsevier Academic Press A3 Book section, Chapters in research books -
Regulation of multiple insulin-like growth factor binding protein genes by 1[alpha],25-dihydroxyvitamin D3
Matilainen M, Malinen M, Saavalainen K, Carlberg C. 2005. Nucleic acids research. 33: 5521-5532 A1 Journal article (refereed), original research -
Regulation of the human cyclin C gene via multiple vitamin D3-responsive regions in its promoter
Sinkkonen L, Malinen M, Saavalainen K, Väisänen S, Carlberg C. 2005. Nucleic acids research. 33: 2440-2451 A1 Journal article (refereed), original research -
Spatio-temporal activation of chromatin on the human CYP24 gene promoter in the presence of 1[alpha],25-dihydroxyvitamin D3
Väisänen S, Dunlop TW, Sinkkonen L, Frank C, Carlberg C. 2005. Journal of molecular biology. 350: 65-77 A1 Journal article (refereed), original research -
Structural determinants of the agonist-independent association of human peroxisome proliferator-activated receptors with coactivators
Molnár F, Matilainen M, Carlberg C. 2005. Journal of biological chemistry. 280: 26543-26556 A1 Journal article (refereed), original research -
The human hyaluronan synthase 2 gene is a primary retinoic acid and epidermal growth factor responding gene
Saavalainen K, Pasonen-Seppänen S, Dunlop TW, Tammi R, Tammi MI, Carlberg C. 2005. Journal of biological chemistry. 280: 14636-14644 A1 Journal article (refereed), original research -
The human peroxisome proliferator-activated receptor [delta] gene is a primary target of 1[alpha],25-dihydroxyvitamin D3 and its nuclear receptor
Dunlop T, Väisänen S, Frank C, Molnár F, Sinkkonen L, Carlberg C. 2005. Journal of molecular biology. 349: 248-260 A1 Journal article (refereed), original research -
A structural basis for the species-specific antagonism of 26,23-lactones on vitamin D signaling
Peräkylä M, Molnar F, Carlberg C. 2004. Chemistry and biology. 11: 1147-1156 A1 Journal article (refereed), original research -
Agonist-dependent and agonist-independent transactivations of the human constitutive androstane receptor are modulated by specific amino acid pairs
Frank C, Molnar F, Matilainen M, Lempiäinen H, Carlberg C. 2004. Journal of biological chemistry. 279: 33558-33566 A1 Journal article (refereed), original research -
Ligand-mediated conformational changes of the VDR are required for gene transactivation
Carlberg C. 2004. Journal of steroid biochemistry and molecular biology. 89-90: 227-232 A1 Journal article (refereed), original research -
Principles of gene regulation by bioactive lipids through members of the nuclear receptor family
Carlberg C. Teoksessa: Schmitz ML, Bacher S(toim.) , 2004. Mechanisms of Signal Transduction and Inducible Gene Expression. s. 77-95. Research signpost A3 Book section, Chapters in research books -
The genes of the coactivator TIF2 and the corepressor SMRT are primary 1alfa,25(OH)2D3 targets
Dunlop TW, Väisänen S, Frank C, Carlberg C. 2004. Journal of steroid biochemistry and molecular biology. 89-90: 257-260 A1 Journal article (refereed), original research -
The highly conserved region of the co-repressor Sin3A functionally interacts with the co-repressor alien
Moehren U, Dressel U, Reeb CA, Väisänen S, Dunlop TW, Carlberg C, Baniahmad A. 2004. Nucleic acids research. 32: 2995-3004 A1 Journal article (refereed), original research -
Using chromatin immunoprecipitation to monitor 1alfa,25-dihydroxyvitamin D3-dependent chromatin activity on the human CYP24 promoter
Väisänen S, Dunlop TW, Frank C, Carlberg C. 2004. Journal of steroid biochemistry and molecular biology. 89-90: 277-279 A1 Journal article (refereed), original research -
Characterization of DNA complexes formed by the nuclear receptor constitutive androstane receptor
Frank C, Macias Gonzalez M, Oinonen C, Dunlop TW, Carlberg C. 2003. Journal of biological chemistry. 278: 43299-43310 A1 Journal article (refereed), original research -
Corepressor excess shifts the two-side chain vitamin D analog gemini from an agonist to an inverse agonist of the vitamin D receptor
Macias Gonzalez M, Samenfeld P, Peräkylä M, Carlberg C. 2003. Molecular endocrinology. 17: 2028-2038 A1 Journal article (refereed), original research -
Current understanding of the function of the nuclear vitamin D receptor in response to its natural and synthetic ligands
Carlberg C. Teoksessa: J Reichrath, M Friedrich, W Tilgen(toim.) , 2003. Vitamin D Analogs in Cancer Prevention and Therapy. s. 29-42. Springer-Verlag A3 Book section, Chapters in research books -
Molecular basis of the selective activity of vitamin D analogues
Carlberg C. 2003. Journal of cellular biochemistry. 88: 274-281 A1 Journal article (refereed), original research -
New vitamin D receptor ligands
Carlberg C, Mourino A. 2003. Expert opinion on therapeutic patents. 13: 761-772 A2 Review article, Literature review, Systematic review -
Structural evaluation of the agonistic action of a vitamin D analog with two side chains binding to the nuclear vitamin D receptor
Väisänen S, Peräkylä M, Kärkkäinen JI, Uskokovic MR, Carlberg C. 2003. Molecular pharmacology. 63: 1230-1237 A1 Journal article (refereed), original research -
The critical role of carboxy-terminal amino acids in ligand-dependent and -independent transactivation of the constitutive androstane receptor
Andersin T, Väisänen S, Carlberg C. 2003. Molecular endocrinology. 17: 234-246 A1 Journal article (refereed), original research -
Critical role of helix 12 of the vitamin D3 receptor for the partial agonism of carboxylic ester antagonists
Väisänen S, Peräkylä M, Kärkkäinen JI, Steinmeyer A, Carlberg C. 2002. Journal of molecular biology. 315: 229-238 A1 Journal article (refereed), original research -
Cross-repression, a functional consequence of the physical interaction of non-liganded nuclear receptors and POU domain transcription factors
Macias Gonzalez M, Carlberg C. 2002. Journal of biological chemistry. 277: 18501-18509 A1 Journal article (refereed), original research -
Differential nuclear receptor signalling from DR4-type response elements
Quack M, Frank C, Carlberg C. 2002. Journal of cellular biochemistry. 86: 601-612 A1 Journal article (refereed), original research -
Modulation of mouse and human phenobarbital-responsive enhancer module by nuclear receptors
Mäkinen J, Frank C, Jyrkkärinne J, Gynther J, Carlberg C, Honkakoski P. 2002. Molecular pharmacology. 62: 366-378 A1 Journal article (refereed), original research -
Orphan nuclear receptor binding site in the human inducible nitric oxide synthase promoter mediates responsiveness to steroid and xenobiotic ligands
Toell A, Kröncke K-D, Kleinert H, Carlberg C. 2002. Journal of cellular biochemistry. 85: 72-82 A1 Journal article (refereed), original research -
Different molecular mechanisms of vitamin D3 receptor antagonists
Toell A, Macias Gonzalez M, Ruf D, Steinmeyer A, Ishizuka S, Carlberg C. 2001. Molecular pharmacology. 59: 1478-1485 A1 Journal article (refereed), original research -
Peroxisome proliferator-activated receptor delta is a specific sensor for teratogenic valproic acid derivatives
Lampen A, Carlberg C, Nau H. 2001. European journal of pharmacology. 431: 25-33 A1 Journal article (refereed), original research -
Single thyroid hormone receptor monomers are competent for co-activator-mediated transactivation
Quack M, Carlberg C. 2001. Biochemical journal. 360: 387-393 A1 Journal article (refereed), original research -
Vitamin D and cancer: Effects of 1,25(OH)2D3 and its analogs on growth control and tumorigenesis
Mork Hansen C , Binderup L, Hamberg KJ, Carlberg C. 2001. FRONTIERS IN BIOSCIENCE. 6: d820-d848 A2 Review article, Literature review, Systematic review