Heli Koukkunen

Risk factors for major adverse cardiovascular events after the first acute coronary syndrome

Okkonen, M; Havulinna, AS; Ukkola, O; Huikuri, H; Pietilä, A; Koukkunen, H; Lehto, S; Mustonen, J; Ketonen, M; Airaksinen, J; Kesäniemi, YA; Salomaa, V. 2021. Annals of medicine. 53: 817-823

Screening for Glucose Perturbations and Risk Factor Management in Dysglycemic Patients With Coronary Artery Disease - A Persistent Challenge in Need of Substantial Improvement: A Report From ESC EORP EUROASPIRE V

Ferrannini, Giulia; De Bacquer, Dirk; De Backer, Guy; Kotseva, Kornelia; Mellbin, Linda; Wood, David; Rydén, Lars; on behalf of the EUROASPIRE V collaborators (incl. Koukkunen; Heli). 2020. Diabetes care. 43: 726-733

Management of dyslipidaemia in patients with coronary heart disease: Results from the ESC-EORP EUROASPIRE V survey in 27 countries

De Backer, Guy; Jankowski, Piotr; Kotseva, Kornelia; Mirrakhimov, Erkin; Reiner, ´eljko; Rydén, Lars; Tokgözoglu, Lale; Wood, David; De Bacquer, Dirk; Abreu, A; Aguiar, C; Badariene, J; Bruthans, J; Castro Conde, A; Cifkova, R; Crowley, J; Davletov; K; De Smeds, D; De Sutter, J; Deckers, J W et al. [incl. Koukkunen, Heli]. 2019. Atherosclerosis. 285: 135-146

Case fatality of acute coronary events is improving even among elderly patients: the FINAMI study 1995-2012

Koukkunen, Heli; Havulinna, Aki S; Lehto, Seppo; Ketonen, Matti; Mustonen, Juha; Airaksinen, Juhani K; Ukkola, Olavi; Kesäniemi, Y Antero; Salomaa, Veikko. 2017. Annals of medicine. 2018; 50: 35-45

Decreased mortality risk due to first acute coronary syndrome in women with postmenopausal hormone therapy use

Tuomikoski P, Salomaa V, Havulinna A, Airaksinen J, Ketonen M, Koukkunen H, Ukkola O, Kesäniemi YA, Lyytinen H, Ylikorkala O, Mikkola TS. 2016. Maturitas. 94: 106-109

Trends in long-term prognosis after acute coronary syndrome

Piironen Marjo, Ukkola Olavi, Huikuri Heikki, Havulinna Aki S, Koukkunen Heli, Mustonen Juha, Ketonen Matti, Lehto Seppo, Airaksinen Juhani, Kesäniemi Y Antero, Salomaa Veikko. 2016. European journal of preventive cardiology. [First Published November 19, 2016]: 1-7

Prognosis of acute coronary events is worse in patients living alone: the FINAMI myocardial infarction register

Lammintausta A, Airaksinen JK, Immonen-Räihä P, Torppa J, Kesäniemi AY, Ketonen M, Koukkunen H, Kärjä-Koskenkari P, Lehto S, Salomaa V, FINAMI Study Group. 2014. European journal of preventive cardiology. 21: 989-996

Socioeconomic Inequalities in the Morbidity and Mortality of Acute Coronary Events in Finland: 1988 to 2002

Lammintausta A, Immonen-Räihä P, Airaksinen JKE, Torppa J, Harald K, Ketonen M, Lehto S, Koukkunen H, Kesäniemi AY, Kärjä-Koskenkari P, Salomaa V. 2012. Annals of epidemiology. 22: 87-93

Vanhusten sepelvaltimotauti kuormittaa mmerkittävästi terveydenhoitojärjestelmää

Koukkunen H, Lehto S, Salomaa V, Ketonen M, Immonen-Räihä P, Kärjä-Koskenkari P, Mustonen J, Airaksinen J, Lehtonen A, Havulinna A, Kesäniemi YA, Pyörälä K, FINAMI-tutkimusryhmä. 2009. Lääkärilehti. 64: 795-802

Coronary events in persons aged 75 years or older in Finland from 1995 to 2002. The FINAMI study

Koukkunen H, Salomaa V, Lehto S, Ketonen M, Immonen-Räihä P, Lehtonen A, Havulinna A, Kesäniemi YA, Pyörälä K, for the FINAMI Study Group. 2008. American journal of geriatric cardiology. 17: 78-86

Long-term prognosis after coronary artery bypass surgery

Ketonen M, Pajunen P, Koukkunen H, Immonen-Räihä P..., Lehto S, Miettinen H, Pyörälä K, Salomaa V, for the FINMONICA/FINAMI Study Group. 2008. International journal of cardiology. 124: 72-79

Muutokset akuuttien sepelvaltimotapahtumien esiintyvyydessä. FINAMI-tutkimuksen tulokset vuosilta 1993-2002

Salomaa V, Ketonen M, Koukkunen H, Immonen-Räihä P, Kärjä-Koskenkari P, Lehtonen A, Torppa J, Kuulasmaa K, Mustonen J, Kesäniemi YA, Pyörälä K, Lehto S, Miettinen H, Jerkkola T, Kesäniemi A, Arstila M, Vuorenmaa T, Airaksinen J, Romo M, Havulinna A. 2007. Lääkärilehti. 62: 2643-2649

Smoking behaviour in European patients with established coronary heart disease

Scholte op Reimer W, de Swart E, de Bacquer D, Pyörälä K, Keil U, Heidrich J, Deckers JW, Kotseva K, Wood D, Boersma E, for the EUROASPIRE Investigators, Lehto S, Lehto R, Koukkunen H, Puhakka M, Savolainen K. 2006. European heart journal. 27: 35-41

The effect of correcting for troponins on trends in coronary heart disease events in Finland during 1993-2002: the FINAMI study

Salomaa V, Ketonen M, Koukkunen H, Immonen-Räihä P, Lehtonen A, Torppa J, Kuulasmaa K, Kesäniemi YA, Pyörälä K, for the FINAMI Study Group, Lehto S, Miettinen H. 2006. European heart journal. 27: 2394-2399

A new definition for myocardial infarction: what difference does it make?

Salomaa V, Koukkunen H, Ketonen M, Immonen-Räihä P, Kärjä-Koskenkari P, Mustonen J, Lehto S, Torppa J, Lehtonen A, Tuomilehto J, Kesäniemi YA, Pyörälä K, for the FINAMI Study Group. 2005. European heart journal. 26: 1719-1725

Effects of long-term fenofibrate therapy on cardiovascular events in 9795 people with type 2 diabetes mellitus (the FIELD study): randomised controlled trial

The Field study investigators, Laakso M, Jantunen A, Kähkönen H, Kortelainen S, Koukkunen H, Laitinen M, Lehto S, Lehto R, Lumiaho A. 2005. The Lancet. 366: 1849-1861

Fenofibrate intervention and event lowering in diabetes (FIELD) study: baseline characteristics and short-term effects of fenofibrate [ISRCTN64783481]

The FIELD Study Investigators, Laakso M, Kortelainen S, Koukkunen H, Lehto S, Lehto R, Lumiaho A, Ruotsalainen S. 2005. Cardiovascular diabetology. 4: article 13 [9 p.]

Five-year risk of developing clinical diabetes after first myocardial infarction: the FINAMI study

Pajunen P, Koukkunen H, Ketonen M, Jerkkola T, Immonen-Räihä P, Kärjä-Koskenkari P, Mähönen M, Niemelä M, Kuulasmaa K, Palomäki P, Mustonen J, Lehtonen A, Arstila M, Vuorenmaa T, Lehto S, Miettinen H, Juolevi A, Torppa J, Tuomilehto J, Kesäniemi YA, Pyörälä K, Salomaa V. 2005. Diabetic medicine. 22: 1334-1337

Myocardial infarction in diabetic and non-diabetic persons with and without prior myocardial infarction: the FINAMI Study

Pajunen P, Koukkunen H, Ketonen M, Jerkkola T, Immonen-Räihä P, Kärjä-Koskenkari P, Kuulasmaa K, Palomäki P, Mustonen J, Lehtonen A, Arstila M, Vuorenmaa T, Lehto S, Miettinen H, Torppa J, Tuomilehto J, Kesäniemi YA, Pyörälä K, Salomaa V. 2005. Diabetologia. 48: 2519-2524

Sydäninfarktidiagnoosin luotettavuus hoitoilmoitus- ja kuomensyyrekisterissä vuosina 1988-2005

Pajunen P, Koukkunen H, Ketonen M, Jerkkola T, Immonen-Räihä P, Kärjä-Koskenkari P, Mähönen M, Niemelä M, Kuulasmaa K, Torppa J, Vuorenmaa T, Lehtonen A, Miettinen H, Mustonen J, Palomäki P, Arstila M, Tuomilehto J, Kesäniemi YA, Pyörälä K, Salomaa V. 2005. Duodecim. 60: 3883-3887

The validity of the Finnish hospital discharge register and causes of death register data on coronary heart disease

Pajunen P, Koukkunen H, Ketonen M, Jerkkola T, Immonen-Räihä P, Kärjä-Koskenkari P, Mähönen M, Niemelä M, Kuulasmaa K, Palomäki P, Mustonen J, Lehtonen A, Arstila M, Vuorenmaa T, Lehto S, Miettinen H, Torppa J, Tuomilehto J, Kesäniemi YA, Pyörälä K. 2005. EUROPEAN JOURNAL OF CARDIOVASCULAR PREVENTION AND REHABILITATION. 12: 132-137

Low-risk patients with chest pain and without evidence of myocardial infarction may be safely discharged from emergency department

Koukkunen H, Pyörälä K, Halinen MO. 2004. European heart journal. 25: 329-334

Decline in out-of-hospital coronary heart disease deaths has contributed the main part to the overall decline in coronary heart disease mortality rates among persons 35 to 64 years of age in Finland

Salomaa V, Ketonen M, Koukkunen H, Immonen-Räihä P, Jerkkola T, Kärjä-Koskenkari P, Mähönen M, Niemelä M, Kuulasmaa K, Palomäki P, Mustonen J, Arstila M, Vuorenmaa T, Lehtonen A, Lehto S, Miettinen H, Torppa J, Tuomilehto J, Kesäniemi YA, Pyörälä K. 2003. Circulation. 108: 691-696

Trends in coronary events in Finland during 1983-1997: the FINAMI study

Salomaa V, Ketonen M, Koukkunen H, Immonen-Räihä P, Jerkkola T, Kärjä-Koskenkari P, Mähönen M, Niemelä M, Kuulasmaa K, Palomäki P, Arstila M, Vuorenmaa T, Lehtonen A, Lehto S, Miettinen H, Torppa J, Tuomilehto J, Kesäniemi YA, Pyörälä K. 2003. European heart journal. 24: 311-319

Biochemical Markers in the Diagnostic and Prognostic Evaluation of Acute Coronary Syndromes

Koukkunen H. 2002. Kuopio University Publications D. Medical Sciences

Myoglobin, creatine kinase MB isoforms and creatine kinase MB mass in early diagnosis of myocardial infarction in patients with acute chest pain

Penttilä K, Koukkunen H, Halinen M, Rantanen T, Pyörälä K, Punnonen K, Penttilä I. 2002. Clinical biochemistry. 35: 647-653

Sepelvaltimotautitapahtumien esiintyvyyden kehityssuunnat Suomessa 1993-1997: FINAMI-tutkimus

Salomaa V, Ketonen M, Koukkunen H, Immonen-Räihä P, Jerkkola T, Kärjä-Koskenkari P, Mähönen M, Kuulasmaa K, Mustonen J, Palomäki P, Arstila M, Vuorenmaa T, Lehtonen A, Lehto S, Miettinen H, Juolevi A, Torppa J, Tuomilehto J, Kesäniemi YA, Pyörälä K. 2002. Lääkärilehti. 57: 3239-3244

Serum and plasma as alternative sample types in analysis of cardiac markers in the clinical routine

Penttilä K, Koukkunen H, Halinen M, Punnonen K, Pyörälä K, Rantanen T, Penttilä I. 2002. Scandinavian journal of clinical and laboratory investigation. 62: 553-560

The pursuit of secondary prevention targets in Czech coronary patients. a comparison of Euroaspire I and II surveys

Mayer O Jr, Simon J, Rosolová H, Dirk DeBacquer, (on behalf Euroaspire I and II Study Groups), Koukkunen H, Lehto S, Lehto R, Pyörälä K. 2002. Central european journal of public health. 10: 107-111

C-reactive proteins, fibrinogen, interleukin-6 and tumour necrosis factor-alfa in the prognostic classification of unstable angina pectoris

Koukkunen H, Penttilä K, Kemppainen A, Halinen M, Penttilä I, Rantanen T, Pyörälä K. 2001. Annals of medicine. 33: 37-47

Differences in the diagnosis of myocardial infarction by troponin T compared with clinical and epidemiologic criteria

Koukkunen H, Penttilä K, Kemppainen A, Penttilä I, Halinen MO, Rantanen T, Pyörälä K. 2001. American journal of cardiology. 88: 727-731

Ruling out myocardial infarction with Troponin T and creatine kinase MB massa: diagnostic and prognostic aspects

Koukkunen H, Penttilä K, Kemppainen A, Penttilä I, Halinen M, Rantanen T, Pyörälä K. 2001. Scandinavian cardiovascular journal. 35: 302-306

Depression after coronary heart disease events

Lehto S, Koukkunen H, Hintikka J, Viinamäki H, Laakso M, Pyörälä K. 2000. Scandinavian cardiovascular journal. 34: 580-583

Overweight and obesity: a major challenge for coronary heart disease secondary prevention in clinical practice in Europe

Montaye M, De Bacquer D, De Backer G, Amouyel P, on behalf of the EUROASPIRE investigators, Koukkunen H, Lehto S, Lehto R, Pyörälä K. 2000. European heart journal. 21: 808-813

Myoglobin, creatine kinase MB, troponin T, and troponin I - rapid bedside assays in patients with acute chest pain

Penttilä K, Koukkunen H, Kemppainen A, Halinen M, Rantanen T, Pyörälä K, Penttilä I. 1999. INTERNATIONAL JOURNAL OF CLINICAL AND LABORATORY RESEARCH. 29: 93-101

Concordance of diet with the recommended cholesterol lowering diet in patients with coronary heart disease

Erkkilä AT, Sarkkinen ES, Koukkunen H, Kemppainen A, Lehto S, Pyörälä K, Uusitupa MIJ. 1998. European journal of clinical nutrition. 52: 279-285

Sepelvaltimotaudin sekundaariprevention toteutuminen KYS:ssa hoidetuilla potilailla: EUROASPIRE-tutkimuksen tuloksia

Koukkunen H, Kemppainen A, Lehto S, Erkkilä A, Sarkkinen E, Uusitupa M, Pyörälä K. 1998. Lääkärilehti. 53: 2029-2041

Troponin T and creatinine kinase isoenzyme MB mass in the diagnosis of myocardial infarction

Koukkunen H, Penttilä K, Kemppainen A, Halinen M, Penttilä I, Rantanen T, Pyörälä K. 1998. Annals of medicine. 30: 488-496

Comparison of the troponin T and troponin I ELISA tests, as measured by microplate immunoassay tecniques, in diagnosing acute myocardial infarction

Penttilä K, Penttilä I, Bonnell R, Kerth P, Koukkunen H, Rantanen T, Svanas G. 1997. Clinical chemistry and laboratory medicine. 35: 767-774

EUROASPIRE. A European Society of Cardiology survey of secondary prevention of coronary heart disease: Principal results

EUROASPIRE Study Group, Kemppainen A, Koukkunen H, Lehto S, Lehto R, Pyörälä K. 1997. European heart journal. 18: 1569-1582

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Risk factors for major adverse cardiovascular events after the first acute coronary syndrome

Screening for Glucose Perturbations and Risk Factor Management in Dysglycemic Patients With Coronary Artery Disease - A Persistent Challenge in Need of Substantial Improvement: A Report From ESC EORP EUROASPIRE V

Management of dyslipidaemia in patients with coronary heart disease: Results from the ESC-EORP EUROASPIRE V survey in 27 countries

Case fatality of acute coronary events is improving even among elderly patients: the FINAMI study 1995-2012

Decreased mortality risk due to first acute coronary syndrome in women with postmenopausal hormone therapy use

Trends in long-term prognosis after acute coronary syndrome

Prognosis of acute coronary events is worse in patients living alone: the FINAMI myocardial infarction register

Socioeconomic Inequalities in the Morbidity and Mortality of Acute Coronary Events in Finland: 1988 to 2002

Vanhusten sepelvaltimotauti kuormittaa mmerkittävästi terveydenhoitojärjestelmää

Coronary events in persons aged 75 years or older in Finland from 1995 to 2002. The FINAMI study

Long-term prognosis after coronary artery bypass surgery

Muutokset akuuttien sepelvaltimotapahtumien esiintyvyydessä. FINAMI-tutkimuksen tulokset vuosilta 1993-2002

Smoking behaviour in European patients with established coronary heart disease

The effect of correcting for troponins on trends in coronary heart disease events in Finland during 1993-2002: the FINAMI study

A new definition for myocardial infarction: what difference does it make?

Effects of long-term fenofibrate therapy on cardiovascular events in 9795 people with type 2 diabetes mellitus (the FIELD study): randomised controlled trial

Fenofibrate intervention and event lowering in diabetes (FIELD) study: baseline characteristics and short-term effects of fenofibrate [ISRCTN64783481]

Five-year risk of developing clinical diabetes after first myocardial infarction: the FINAMI study

Myocardial infarction in diabetic and non-diabetic persons with and without prior myocardial infarction: the FINAMI Study

Sydäninfarktidiagnoosin luotettavuus hoitoilmoitus- ja kuomensyyrekisterissä vuosina 1988-2005

The validity of the Finnish hospital discharge register and causes of death register data on coronary heart disease

Low-risk patients with chest pain and without evidence of myocardial infarction may be safely discharged from emergency department

Decline in out-of-hospital coronary heart disease deaths has contributed the main part to the overall decline in coronary heart disease mortality rates among persons 35 to 64 years of age in Finland

Trends in coronary events in Finland during 1983-1997: the FINAMI study

Biochemical Markers in the Diagnostic and Prognostic Evaluation of Acute Coronary Syndromes

Myoglobin, creatine kinase MB isoforms and creatine kinase MB mass in early diagnosis of myocardial infarction in patients with acute chest pain

Sepelvaltimotautitapahtumien esiintyvyyden kehityssuunnat Suomessa 1993-1997: FINAMI-tutkimus

Serum and plasma as alternative sample types in analysis of cardiac markers in the clinical routine

The pursuit of secondary prevention targets in Czech coronary patients. a comparison of Euroaspire I and II surveys

C-reactive proteins, fibrinogen, interleukin-6 and tumour necrosis factor-alfa in the prognostic classification of unstable angina pectoris

Differences in the diagnosis of myocardial infarction by troponin T compared with clinical and epidemiologic criteria

Ruling out myocardial infarction with Troponin T and creatine kinase MB massa: diagnostic and prognostic aspects

Depression after coronary heart disease events

Overweight and obesity: a major challenge for coronary heart disease secondary prevention in clinical practice in Europe

Myoglobin, creatine kinase MB, troponin T, and troponin I - rapid bedside assays in patients with acute chest pain

Concordance of diet with the recommended cholesterol lowering diet in patients with coronary heart disease

Sepelvaltimotaudin sekundaariprevention toteutuminen KYS:ssa hoidetuilla potilailla: EUROASPIRE-tutkimuksen tuloksia

Troponin T and creatinine kinase isoenzyme MB mass in the diagnosis of myocardial infarction

Comparison of the troponin T and troponin I ELISA tests, as measured by microplate immunoassay tecniques, in diagnosing acute myocardial infarction

EUROASPIRE. A European Society of Cardiology survey of secondary prevention of coronary heart disease: Principal results