I am an Academy of Finland Research Fellow with more than 10 years of experience in applied and translational spectroscopy. My research interests range from applied spectroscopy, through multivariate and machine learning analysis in biospectroscopy, to computational biophotonics, all with the aim of bench-to-bedside translational of spectroscopy-based innovation for state-of-the-art optical characterization and diagnosis of biological tissue pathologies.
I currently lead the Biomedical Spectroscopy Lab (BSL, est. 2018), a multi-disciplinary team of Physicists and Engineers focused on applied spectroscopy and computational biophotonics research.
Research groups
Publications
75 items-
3-D T1 relaxation time measurements in an equine model of subtle post-traumatic osteoarthritis using MB-SWIFT
Pala, Swetha; Hänninen, Nina E; Mohammadi, Ali; Ebrahimi, Mohammadhossein; te Moller, Nikae CR; Brommer, Harold; René van Weeren, P; Mäkelä, Janne TA; Korhonen, Rami K; Afara, Isaac O; Töyräs, Juha; Mikkonen, Santtu; Nissi, Mikko J; Nykänen, Olli. 2023. Journal of orthopaedic research. [Epub ahead of print 31 May 2023]: 1-10 -
Characterisation of Cartilage Damage via Fusing Mid-Infrared, Near-Infrared, and Raman Spectroscopic Data
Shaikh, Rubina; Tafintseva, Valeria; Nippolainen, Ervin; Virtanen, Vesa; Solheim, Johanne; Zimmermann, Boris; Saarakkala, Simo; Töyräs, Juha; Kohler, Achim; Afara, Isaac O. 2023. Journal of personalized medicine. 13: -
Impact of experimental setup parameters on the measurement of articular cartilage optical properties in the visible and short near-infrared spectral bands
Kafian-Attari, Iman; Nippolainen, Ervin; Bergmann, Florian; Mirhashemi, Arash; Paakkari, Petri; Foschum, Florian; Kienle, Alwin; Töyräs, Juha; Afara, Isaac O.. 2023. Biomedical optics express. 14: 3397-3412 -
Near-infrared spectroscopic assessment of patellar tendon mechanics
Kositsky, Adam; Torniainen, Jari; Stenroth, Lauri; Nippolainen, Ervin; Mäkelä, Janne T.A.; Paakkari, Petri; Kröger, Heikki; Töyräs, Juha; Korhonen, Rami K.; Afara, Isaac O.. 2023. -
Near-infrared spectroscopy for structural bone assessment
Sharma, Varun J; Adegoke, John A; Afara, Isaac O; Stok, Kathryn; Poon, Eric; Gordon, Claire L; Wood, Bayden R; Raman, Jaishankar. 2023. Bone & joint open. 4: 250-261 -
Patellar tendon and tibial cartilage viscoelastic properties are inversely related in osteoarthritic knees
Kositsky, Adam; Linus, Awuniji; Stenroth, Lauri; Mononen, Mika E.; Nippolainen, Ervin; Kröger, Heikki; Töyräs, Juha; Mäkelä, Janne T.A.; Tanska, Petri; Afara, Isaac O.; Korhonen, Rami K.. 2023. Transactions of the annual meeting of the Orthopaedic Research Society -
Raman Spectroscopy and Machine Learning Enables Estimation of Articular Cartilage Structural, Compositional, and Functional Properties
Shehata, Eslam; Nippolainen, Ervin; Shaikh, Rubina; Ronkainen, Ari Petteri; Töyräs, Juha; Sarin, Jaakko K; Afara, Isaac O. 2023. Annals of biomedical engineering. [Epub ahead of print 16 June 2023]: 1-12 -
Visible and Near-Infrared Spectroscopy Enables Differentiation of Normal and Early Osteoarthritic Human Knee Joint Articular Cartilage
Linus, Awuniji; Tanska, Petri; Sarin, Jaakko K.; Nippolainen, Ervin; Tiitu, Virpi; Mäkelä, Janne T.A.; Töyräs, Juha; Korhonen, Rami K.; Mononen, Mika E.; Afara, Isaac O.. 2023. Annals of biomedical engineering. [Epub ahead of print 18 June 2023]: 1-13 -
Assessment of Ligament Viscoelastic Properties Using Raman Spectroscopy
Cui, Andy; Nippolainen, Ervin; Shaikh, Rubina; Torniainen, Jari; Ristaniemi, Aapo; Finnilä, Mikko; Korhonen, Rami K.; Saarakkala, Simo; Herzog, Walter; Töyräs, Juha; Afara, Isaac O.. 2022. Annals of biomedical engineering. 50: 1134-1142 -
Elastic and viscoelastic human patellar tendon regional properties
Kositsky, Adam; Stenroth, Lauri; Nippolainen, Ervin; Mäkelä, Janne; Paakkari, Petri; Torniainen, Jari; Kröger, Heikki; Afara, Isaac; Korhonen, Rami. 2022.