JAANA HARTIKAINEN

Contact info

RESEARCH GROUPS - UEF

• 
  Non-coding RNAs in Breast Cancer
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  Molecular Pathology and Genetics of Cancer
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  Predicting the outcome and toxicity in radiotherapy of head and neck cancers - TIARA

Publications

• Dorling, Leila; Carvalho, Sara; Allen, Jamie; González-Neira, Anna; Luccarini, Craig; Wahlström, Cecilia; Pooley, Karen A.; Parsons, Michael T.; Fortuno, Cristina; Wang, Qin; Bolla, Manjeet K.; Dennis, Joe; Keeman, Renske M.; Alonso, Rosario; Álvarez, Nuria; Herraez, Belen; Fernandez, Victoria; Núñez-Torres, Rocio; Osorio, Ana; Valcich, Jeanette et al. [incl. Hartikainen, Jaana; Kosma, Veli-Matti;. 2021. Breast Cancer Risk Genes - Association Analysis in More than 113,000 Women The new england journal of medicine 384 5: 428-439. 2021
• Launonen, Kaisa-Mari; Paakinaho, Ville; Sigismondo, Gianluca; Malinen, Marjo; Sironen, Reijo; Hartikainen, Jaana M; Laakso, Hanna; Visakorpi, Tapio; Krijgsveld, Jeroen; Niskanen, Einari A; Palvimo, Jorma J. 2021. Chromatin-directed proteomics-identified network of endogenous androgen receptor in prostate cancer cells Oncogene 40 27: 4567-4579. 2021
• Morra, Anna; Escala-Garcia, Maria; Beesley, Jonathan; Keeman, Renske; Canisius, Sander; Ahearn, Thomas U; Andrulis, Irene L; Anton-Culver, Hoda; Arndt, Volker; Auer, Paul L; Augustinsson, Annelie; Beane Freeman, Laura E; Becher, Heiko; Beckmann, Matthias W; Behrens, Sabine; Bojesen, Stig E; Bolla, Manjeet K; Brenner, Hermann; Brüning, Thomas; Buys, Saundra S; et al; [incl. Hartikainen, Jaana; Mann. 2021. Association of germline genetic variants with breast cancer-specific survival in patient subgroups defined by clinic-pathological variables related to tumor biology and type of systemic treatment Breast cancer research 23 1: 86. 2021
• Park, JooYong; Choi, Ji-Yeob; Choi, Jaesung; Chung, Seokang; Song, Nan; Park, Sue K; Han, Wonshik; Noh, Dong-Young; Ahn, Sei-Hyun; Lee, Jong Won; Kim, Mi Kyung; Jee, Sun Ha; Wen, Wanqing; Bolla, Manjeet K; Wang, Qin; Dennis, Joe; Michailidou, Kyriaki; Shah, Mitul; Conroy, Don M; Harrington, Patricia A; et al; [incl. Mannermaa, Arto; Hartikainen, Jaana]. 2021. Gene-Environment Interactions Relevant to Estrogen and Risk of Breast Cancer: Can Gene-Environment Interactions Be Detected Only among Candidate SNPs from Genome-Wide Association Studies? Cancer 13 10: 2370. 2021
• Kärkkäinen, Emmi; Heikkinen, Sami; Tengström, Maria; Kosma, Veli-Matti; Mannermaa, Arto; Hartikainen, Jaana M. 2021. The debatable presence of PIWI-interacting RNAs in invasive breast cancer Cancer medicine 10 11: 3593 - 3603. 2021
• Behravan, Hamid; Hartikainen, Jaana M; Tengström, Maria; Kosma, Veli-Matti; Mannermaa, Arto. 2020. Predicting Breast Cancer Risk Using Interacting Genetic and Demographic Factors and Machine Learning Scientific reports 10 1: 11044. 2020
• Eneh, Stralina; Heikkinen, Sami; Hartikainen, Jaana M; Kuopio, Teijo; Mecklin, Jukka-Pekka; Kosma, Veli-Matti; Mannermaa, Arto. 2020. MicroRNAs Associated With Biological Pathways of Left- And Right-sided Colorectal Cancer Anticancer research 40 7: 3713-3722. 2020
• Fachal, L; Aschard, H; Beesley, J; Barnes, DR; Allen, J; Kar, S; Pooley, KA; Dennis, J; Michailidou, K; Turman, C; Soucy, P; Lemaçon, A; Lush, M; Tyrer, JP; Ghoussaini, M; Marjaneh, MM; Jiang, X; Agata, S; Aittomäki, K; Alonso, MR; et al. [incl. Hartikainen, J; Kosma, VM; Mannermaa, A; Tengström, M]. 2020. Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes Nature genetics 52: 56-73. 2020
• Kujala, J; Hartikainen, JM; Tengström, M; Sironen, R; Kosma, VM; Mannermaa, A. 2020. High Mutation Burden of Circulating Cell-Free DNA in Early-Stage Breast Cancer Patients Is Associated With a Poor Relapse-Free Survival Cancer medicine 9 16: 5922-5931. 2020
• Escala-Garcia, M; Guo, Q; Dörk, T; Canisius, S; Keeman, R; Dennis, J; Beesley, J; Lecarpentier, J; Bolla, MK; Wang, Q; Abraham, J; Andrulis, IL; Anton-Culver, H; Arndt, V; Auer, PL; Beckmann, MW; Behrens, S; Benitez, J; Bermisheva, M; Bernstein, L; et al. (Incl. Hartikainen, Jaana; Kosma, Veli-Matti; Mannermaa, Arto; Tengström, Maria). 2019. Genome-wide association study of germline variants and breast cancer-specific mortality British journal of cancer 120: 647-657. 2019
• Härkönen, K; Oikari, S; Kyykallio, H; Capra, J; Hakkola, S; Ketola, K; Thanigai Arasu, U; Daaboul, G; Malloy, A; Oliveira, C; Jokelainen, O; Sironen, R; Hartikainen, JM; Rilla, K. 2019. CD44s Assembles Hyaluronan Coat on Filopodia and Extracellular Vesicles and Induces Tumorigenicity of MKN74 Gastric Carcinoma Cells Cells 8 3: 276. 2019
• Pölönen, P; Jawahar Deen, A; Leinonen, HM; Jyrkkänen, HK; Kuosmanen, S; Mononen, M; Jain, A; Tuomainen, T; Pasonen-Seppänen, S; Hartikainen, JM; Mannermaa, A; Nykter, M; Tavi, P; Johansen, T; Heinäniemi, M; Levonen, AL. 2019. Nrf2 and SQSTM1/p62 jointly contribute to mesenchymal transition and invasion in glioblastoma Oncogene 38: 7473-7490. 2019
• Sallinen, H; Janhonen, S; Pölönen, P; Niskanen, H; Liu, OH; Kivelä, A; Hartikainen, JM; Anttila, M; Heinäniemi, M; Ylä-Herttuala, S; Kaikkonen, MU. 2019. Comparative transcriptome analysis of matched primary and distant metastatic ovarian carcinoma Bmc cancer 19: 1121. 2019
• Seibold, P; Auvinen, A; Averbeck, D; Bourguignon, M; Hartikainen, JM; Hoeschen, C; Laurent, O; Noël, G; Sabatier, L; Salomaa, S; Blettner, M. 2019. Clinical and epidemiological observations on individual radiation sensitivity and susceptibility International journal of radiation biology 2020; 96 3: 324-339. 2019
• Tervasmäki, Anna; Mantere, Tuomo; Hartikainen, Jaana M; Kauppila, Salla; Lee, Hang-Mao; Koivuluoma, Susanna; Grip, Mervi; Karihtala, Peeter; Jukkola-Vuorinen, Arja; Mannermaa, Arto; Winqvist, Robert; Pylkäs, Katri. 2018. Rare missense mutations in RECQL and POLG associate with inherited predisposition to breast cancer International journal of cancer 142 11: 2286-2292. 2018
• Horne, HN; Oh, H; Sherman, ME; Palakal, M; Hewitt, SM; Schmidt, MK; Milne, RL; Hardisson, D; Benitez, J; Blomqvist, C; Bolla, MK; Brenner, H; Chang-Claude, J; Cora, R; Couch, FJ; Cuk, K; Devilee, P; Easton, DF; Eccles, DM; Eilber, U; et al [Incl Mannermaa, A; Tengström, M]. 2018. E-cadherin breast tumor expression, risk factors and survival: Pooled analysis of 5,933 cases from 12 studies in the Breast Cancer Association Consortium Scientific reports 8 1: 6574. 2018
• Behravan, Hamid; Hartikainen, Jaana M; Tengström, Maria; Pylkäs, Katri; Winqvist, Robert; Kosma, Veli-Matti; Mannermaa, Arto. 2018. Machine learning identifies interacting genetic variants contributing to breast cancer risk: a case study in Finnish cases and controls Scientific Reports 8: 13149. 2018
• Guo Q, Burgess S, Turman C, Bolla MK, Wang Q, Lush M, Abraham J, Aittomäki K, Andrulis IL, Apicella C, Arndt V, Barrdahl M, Benitez J, Berg CD, Blomqvist C, Bojesen SE, Bonanni B, Brand JS, Brenner H, Broeks A et al. [Incl. Hartikainen J, Kataja V, Kosma V-M, Mannermaa A]. 2017. Body mass index and breast cancer survival: a Mendelian randomization analysis. INTERNATIONAL JOURNAL OF EPIDEMIOLOGY 46 6: 1814-1822. 2017
• Mantere T, Tervasmäki A, Nurmi A, Rapakko K, Kauppila S, Tang J, Schleutker J, Kallioniemi A, Hartikainen JM, Mannermaa A, Nieminen P, Hanhisalo R, Lehto S, Suvanto M, Grip M, Jukkola-Vuorinen A, Tengström M, Auvinen P, Kvist A, Borg Å et al. 2017. Case-control analysis of truncating mutations in DNA damage response genes connects TEX15 and FANCD2 with hereditary breast cancer susceptibility. Scientific Reports 7 1: 681. 2017
• Michailidou K, Lindstrom S, Dennis J, Beesley J, Hui S, Kar S, Lemacon A, Soucy P, Glubb D, Rostamianfar A, Bolla MK, Wang Q, Tyrer J, Dicks E, Lee A, Wang ZM, Allen J, Keeman R, Eilber U, French JD et al.. 2017. Association analysis identifies 65 new breast cancer risk loci. Nature 551 7678: 92-94. 2017
• Milne RL, Kuchenbaecker KB, Michailidou K, Beesley J, Kar S, Lindström S, Hui S, Lemaçon A, Soucy P, Dennis J, Jiang X, Rostamianfar A, Finucane H, Bolla MK, McGuffog L, Wang Q, Aalfs CM, ABCTB Investigators, Adams M, Adlard J et al [incl. Hartikainen Juha, Mannermaa Arto, Tengström Maria]. 2017. Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer. NATURE GENETICS 49: 1767-1778. 2017
• Hartikainen, Jaana. 2016. KEAP1-geenin variantit rintasyövässä. BestPractice: Onkologia/Hematologia 14: 12-13. 2016
• Ovarian Cancer Association Consortium, Breast Cancer Association Consortium, Consortium of Modifiers of BRCA1 and BRCA2, Hollestelle Antoinette, van der Baan Frederieke H, Berchuck Andrew, Johnatty Sharon E, Aben Katja K, Agnarsson Bjarni A, Aittomäki Kristiina, Alducci Elisa, Andrulis Irene L, Anton-Culver Hoda, Antonenkova Natalia N, Antoniou Antonis C, Apicella Carmel, Arndt Volker, Arnold Norb. 2016. No clinical utility of KRAS variant rs61764370 for ovarian or breast cancer. GYNECOLOGIC ONCOLOGY 141 2: 386-401. 2016
• Pelttari Liisa M, Khan Sofia, Vuorela Mikko, Kiiski Johanna I, Vilske Sara, Nevanlinna Viivi, Ranta Salla, Schleutker Johanna, Winqvist Robert, Kallioniemi Anne, Dörk Thilo, Bogdanova Natalia V, Figueroa Jonine, Pharoah Paul DP, Schmidt Marjanka K, Dunning Alison M, García-Closas Montserrat, Bolla Manjeet K, Dennis Joe, Michailidou Kyriaki et al. 2016. RAD51B in Familial Breast Cancer. PLOS ONE [ONLINE] 11 5: e0153788. 2016
• Southey MC, Goldgar DE, Winqvist R, Pylkäs K, Couch F, Tischkowitz M, Foulkes WD, Dennis J, Michailidou K, van Rensburg EJ, Heikkinen T, Nevanlinna H, Hopper JL, Dörk T, Claes KB, Reis-Filho J, Teo ZL, Radice P, Catucci I, Peterlongo P et al. 2016. PALB2, CHEK2 and ATM rare variants and cancer risk: Data from COGS. JOURNAL OF MEDICAL GENETICS 53 12: 800-811. 2016
• Zeng Chenjie, Guo Xingyi, Long Jirong, Kuchenbaecker Karoline B, Droit Arnaud, Michailidou Kyriaki, Ghoussaini Maya, Kar Siddhartha, Freeman Adam, Hopper John L, Milne Roger L, Bolla Manjeet K, Wang Qin, Dennis Joe, Agata Simona, Ahmed Shahana, Aittomäki Kristiina, Andrulis Irene L, Anton-Culver Hoda, Antonenkova Natalia N et al. 2016. Identification of independent association signals and putative functional variants for breast cancer risk through fine-scale mapping of the 12p11 locus. BREAST CANCER RESEARCH [ONLINE: HTTP://BREAST-CANCER-RESEARCH.COM/] 18 1: 64. 2016
• Michailidou Kyriaki, Beesley Jonathan, Lindstrom Sara, Canisius Sander, Dennis Joe, Lush Michael J, Maranian Mel J, Bolla Manjeet K, Wang Qin, Shah Mitul, Perkins Barbara J, Czene Kamila, Eriksson Mikael, Darabi Hatef, Brand Judith S, Bojesen Stig E, Nordestgaard Børge G, Flyger Henrik, Nielsen Sune F, Rahman Nazneen et al (incl. Arto Mannermaa, Jaana Hartikainen, Veli-Matti Kosma, Vesa Kataja). 2015. Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer. NATURE GENETICS 47: 373-380. 2015
• Sobral-Leite Marcelo, Wesseling Jelle, Smit Vincent THBM, Nevanlinna Heli, van Miltenburg Martine H, Sanders Joyce, Hofland Ingrid, Blows Fiona M, Coulson Penny, Patrycja Gazinska, Schellens Jan HM, Fagerholm Rainer, Heikkilä Päivi, Aittomäki Kristiina, Blomqvist Carl, Provenzano Elena, Ali Hamid Raza, Figueroa Jonine, Sherman Mark, Lissowska Jolanta et al (incl. Arto Mannermaa, Vesa Kataja, Veli-. 2015. Annexin A1 expression in a pooled breast cancer series: association with tumor subtypes and prognosis. BMC MEDICINE 13: 156. 2015
• Seibold Petra, Schmezer Peter, Behrens Sabine, Michailidou Kyriaki, Bolla Manjeet K, Wang Qin, Flesch-Janys Dieter, Nevanlinna Heli, Fagerholm Rainer, Aittomäki Kristiina, Blomqvist Carl, Margolin Sara, Mannermaa Arto, Kataja Vesa, Kosma Veli-Matti, Hartikainen Jaana M, Lambrechts Diether, Wildiers Hans, Kristensen Vessela, Alnæs Grethe Grenaker et al. 2015. A polymorphism in the base excision repair gene PARP2 is associated with differential prognosis by chemotherapy among postmenopausal breast cancer patients. BMC CANCER [ONLINE: HTTP://WWW.BIOMEDCENTRAL.COM/BMCCANCER/] 15 1: 978. 2015
• Pirie Ailith, Guo Qi, Kraft Peter, Canisius Sander, Eccles Diana M, Rahman Nazneen, Nevanlinna Heli, Chen Constance, Khan Sofia, Tyrer Jonathan, Bolla Manjeet K, Wang Qin, Dennis Joe, Michailidou Kyriaki, Lush Michael, Dunning Alison M, Shah Mitul, Czene Kamila, Darabi Hatef, Eriksson Mikael et al (incl. Vesa Kataja, Jaana Hartikainen, Veli-Matti Kosma). 2015. Common germline polymorphisms associated with breast cancer specific survival. BREAST CANCER RESEARCH [ONLINE: HTTP://BREAST-CANCER-RESEARCH.COM/] 17 58: -. 2015
• Orr Nick, Dudbridge Frank, Dryden Nicola, Maguire Sarah, Novo Daniela, Perrakis Eleni, Johnson Nichola, Ghoussaini Maya, Hopper John L, Southey Melissa C, Apicella Carmel, Stone Jennifer, Schmidt Marjanka K, Broeks Annegien, Van't Veer Laura J, Hogervorst Frans B, Fasching Peter A, Haeberle Lothar, Ekici Arif B, Beckmann Matthias W et al (incl. Arto Mannermaa, Vesa Kataja, Veli-Matti Kosma, Jaana. 2015. Fine-mapping identifies two additional breast cancer susceptibility loci at 9q31.2. HUMAN MOLECULAR GENETICS 24 10: 2966-2984. 2015
• Zhang Ben, Shu Xiao-Ou, Delahanty Ryan J, Zeng Chenjie, Michailidou Kyriaki, Bolla Manjeet K, Wang Qin, Dennis Joe, Wen Wanqing, Long Jirong, Li Chun, Dunning Alison M, Chang-Claude Jenny, Shah Mitul, Perkins Barbara J, Czene Kamila, Darabi Hatef, Eriksson Mikael, Bojesen Stig E, Nordestgaard Børge G et al. (incl. Mannermaa A, Kataja V, Kosma V-M, Hartikainen JM). 2015. Height and Breast Cancer Risk: Evidence From Prospective Studies and Mendelian Randomization. JOURNAL OF THE NATIONAL CANCER INSTITUTE 107 11: djv219. 2015
• Mavaddat Nasim, Pharoah Paul DP, Michailidou Kyriaki, Tyrer Jonathan, Brook Mark N, Bolla Manjeet K, Wang Qin, Dennis Joe, Dunning Alison M, Shah Mitul, Luben Robert, Brown Judith, Bojesen Stig E, Nordestgaard Børge G, Nielsen Sune F, Flyger Henrik, Czene Kamila, Darabi Hatef, Eriksson Mikael, Peto Julian et al (incl. Arto Mannermaa). 2015. Prediction of Breast Cancer Risk Based on Profiling With Common Genetic Variants. JOURNAL OF THE NATIONAL CANCER INSTITUTE 107 5: djv036. 2015
• Lei J, Rudolph A, Moysich KB, Behrens S, Goode EL, Bolla MK, Dennis J, Dunning AM, Easton DF, Wang Q, Benitez J, Hopper JL, Southey MC, Schmidt MK, Broeks A, Fasching PA, Haeberle L, Peto J, Dos-Santos-Silva I, Sawyer EJ et al.. 2015. Genetic variation in the immunosuppression pathway genes and breast cancer susceptibility: a pooled analysis of 42,510 cases and 40,577 controls from the Breast Cancer Association Consortium. HUMAN GENETICS 135 1: 137-154. 2015
• Kabisch Maria, Bermejo Justo Lorenzo, Dünnebier Thomas, Ying Shibo, Michailidou Kyriaki, Bolla Manjeet K, Wang Qin, Dennis Joe, Shah Mitul, Perkins Barbara J, Czene Kamila, Darabi Hatef, Eriksson Mikael, Bojesen Stig E, Nordestgaard Børge G, Nielsen Sune F, Flyger Henrik, Lambrechts Diether, Neven Patrick, Peeters Stephanie et al (incl.. 2015. Inherited variants in the inner centromere protein (INCENP) gene of the chromosomal passenger complex contribute to the susceptibility of ER-negative breast cancer. CARCINOGENESIS 36 2: 256-271. 2015
• Hartikainen Jaana M, Tengström Maria, Winqvist Robert, Jukkola-Vuorinen Arja, Pylkäs Katri, Kosma Veli-Matti, Soini Ylermi, Mannermaa Arto. 2015. KEAP1 Genetic Polymorphisms Associate with Breast Cancer Risk and Survival Outcomes. CLINICAL CANCER RESEARCH 21 onlinefirst January 14, 2015: -. 2015
• Guo Qi, Schmidt Marjanka K, Kraft Peter, Canisius Sander, Chen Constance, Khan Sofia, Tyrer Jonathan, Bolla Manjeet K, Wang Qin, Dennis Joe, Michailidou Kyriaki, Lush Michael, Kar Siddhartha, Beesley Jonathan, Dunning Alison M, Shah Mitul, Czene Kamila, Darabi Hatef, Eriksson Mikael, Lambrechts Diether et al. (incl. Mannermaa Arto). 2015. Identification of Novel Genetic Markers of Breast Cancer Survival. JOURNAL OF THE NATIONAL CANCER INSTITUTE 107 5: djv081. 2015
• Glubb Dylan M, Maranian Mel J, Michailidou Kyriaki, Pooley Karen A, Meyer Kerstin B, Kar Siddhartha, Carlebur Saskia, O'Reilly Martin, Betts Joshua A, Hillman Kristine M, Kaufmann Susanne, Beesley Jonathan, Canisius Sander, Hopper John L, Southey Melissa C, Tsimiklis Helen, Apicella Carmel, Schmidt Marjanka K, Broeks Annegien, Hogervorst Frans B et al (incl. Arto Mannermaa, Jaana Hartikainen, Vesa. 2015. Fine-scale mapping of the 5q11.2 breast cancer locus reveals at least three independent risk variants regulating MAP3K1. AMERICAN JOURNAL OF HUMAN GENETICS 96 1: 5-20. 2015
• Lei Jieping, Rudolph Anja, Moysich Kirsten B, Rafiq Sajjad, Behrens Sabine, Goode Ellen L, Pharoah Paul PD, Seibold Petra, Fasching Peter A, Andrulis Irene L, Kristensen Vessela N, Couch Fergus J, Hamann Ute, Hooning Maartje J, Nevanlinna Heli, Eilber Ursula, Bolla Manjeet K, Dennis Joe, Wang Qin, Lindblom Annika et al (incl. Mannermaa Arto, Kosma Veli-Matti, Hartikainen Jaana M, Kataja Vesa). 2015. Assessment of variation in immunosuppressive pathway genes reveals TGFBR2 to be associated with prognosis of estrogen receptor-negative breast cancer after chemotherapy. BREAST CANCER RESEARCH [ONLINE: HTTP://BREAST-CANCER-RESEARCH.COM/] 17 18: -. 2015
• Milne RL, Burwinkel B, Michailidou K, Arias-Perez JI, Zamora MP, Menéndez-Rodríguez P, Hardisson D, Mendiola M, González-Neira A, Pita G, Alonso MR, Dennis J, Wang Q, Bolla MK, Swerdlow A, ..., Mannermaa A, Kataja V, Kosma VM, Hartikainen JM, et al.. 2014. Common non-synonymous SNPs associated with breast cancer susceptibility: findings from the Breast Cancer Association Consortium. HUMAN MOLECULAR GENETICS 23 22: 6096-6111. 2014
• Spurdle Amanda B, Couch Fergus J, Parsons Michael T, McGuffog Lesley, Barrowdale Daniel, Bolla Manjeet K, Wang Qin, Healey Sue, Schmutzler Rita Katharina, Wappenschmidt Barbara, Rhiem Kerstin, Hahnen Eric, Engel Christoph, Meindl Alfons, Ditsch Nina, Norbert Arnold, Plendl Hansjoerg, Niede et al. (incl. Hartikainen Jaana)racher Dieter, Sutter Christian, Wang-Gohrke Shan,. 2014. Refined histopathological predictors of BRCA1 and BRCA2 mutation status: a large-scale analysis of breast cancer characteristics from the BCAC, CIMBA, and ENIGMA consortia. BREAST CANCER RESEARCH [ONLINE: HTTP://BREAST-CANCER-RESEARCH.COM/] 16: 3419. 2014
• Schoeps Anja, Rudolph Anja, Seibold Petra, Dunning Alison M, Milne Roger L, Bojesen Stig E, Swerdlow Anthony, Andrulis Irene, Brenner Hermann, Behrens Sabine, Orr Nicholas, Jones Michael, Ashworth Alan, Li Jingmei, Cramp Helen, Connley Dan, Czene Kamila, Darabi Hatef, Chanock Stephen J, Lissowska Jolanta et al (incl Kosma Veli-Matti, Kataja Vesa, Hartikainen Jaana M, Mannermaa Arto). 2014. Identification of new genetic susceptibility loci for breast cancer through consideration of gene-environment interactions. GENETIC EPIDEMIOLOGY 38 1: 84-93. 2014
• Sawyer Elinor, Roylance Rebecca, Petridis Christos, Brook Mark N, Nowinski Salpie, Papouli Efterpi, Fletcher Olivia, Pinder Sarah, Hanby Andrew, Kohut Kelly, Gorman Patricia, Caneppele Michele, Peto Julian, dos Santos Silva Isabel, Johnson Nichola, Swann Ruth, Dwek Miriam, Perkins Katherine-Anne, Gillett Cheryl, Houlston Richard et al (incl. Mannermaa Arto, Kataja Vesa, Kosma Veli-Matti, Hartikain. 2014. Genetic predisposition to in situ and invasive lobular carcinoma of the breast. PLOS GENETICS [ONLINE) 10 4: e1004285. 2014
• Rudolph A, Milne RL, Truong T, Knight JA, Seibold P, Flesch-Janys D, Behrens S, Eilber U, Bolla MK, Wang Q, Dennis J, Dunning AM, Shah M, ..., Mannermaa A, Kataja V, Kosma VM, Hartikainen JM, et al.. 2014. Investigation of gene-environment interactions between 47 newly identified breast cancer susceptibility loci and environmental risk factors. INTERNATIONAL JOURNAL OF CANCER 136 6: E685-E696. 2014
• Purrington KS, Slettedahl S, Bolla MK, Michailidou K, Czene K, Nevanlinna H, Bojesen SE, Andrulis IL, Cox A, Hall P, Carpenter J, Yannoukakos D, Haiman CA, Fasching PA, Mannermaa A, ...,Hartikainen JM, Kosma VM, Kataja V, et al.. 2014. Genetic variation in mitotic regulatory pathway genes is associated with breast tumor grade. HUMAN MOLECULAR GENETICS 23 22: 6034-6046. 2014
• Milne RL, Herranz J, Michailidou K, Dennis J, Tyrer JP, Zamora MP, Arias-Perez JI, González-Neira A, Pita G, Alonso MR, Wang Q, Bolla MK, Czene K, Eriksson M, Humphreys K, Darabi H,..., Mannermaa A, Kataja V, Kosma VM, Hartikainen J, et al.. 2014. A large-scale assessment of two-way SNP interactions in breast cancer susceptibility using 46 450 cases and 42 461 controls from the breast cancer association consortium. HUMAN MOLECULAR GENETICS 23 7: 1934-1946. 2014
• Lin WY, Camp NJ, Ghoussaini M, Beesley J, Michailidou K, Hopper JL, Apicella C, Southey MC, Stone J, Schmidt MK, Broeks A, Van't Veer LJ, Th Rutgers EJ, Muir K, Lophatananon A, Stewart-Brown S, ..., Mannermaa A, Kataja V, Kosma VM, Hartikainen JM, kConFab Investigators; Australian Ovarian Cancer Study Group, et al.. 2014. Identification and characterization of novel associations in the CASP8/ALS2CR12 region on chromosome 2 with breast cancer risk. HUMAN MOLECULAR GENETICS 2014: 1-14. 2014
• Mantere T, Haanpää M, Hanenberg H, Schleutker J, Kallioniemi A, Kähkönen M, Parto K, Avela K, Aittomäki K, von Koskull H, Hartikainen JM, Kosma VM, Laasanen SL, Mannermaa A, Pylkäs K, Winqvist R. 2014. Finnish Fanconi anemia mutations and hereditary predisposition to breast and prostate cancer. CLINICAL GENETICS (COPENHAGEN) 88: 68-73. 2014
• Luostari Kaisa, Hartikainen Jaana M, Tengström Maria, Palvimo Jorma J, Kataja Vesa, Mannermaa Arto, Kosma Veli-Matti. 2014. Type II Transmembrane Serine Protease Gene Variants Associate with Breast Cancer. PLOS ONE [ONLINE] 9 7: e102519. 2014
• Li Jingmei, Lindström Linda S, Foo Jia N, Rafiq Sajjad, Schmidt Marjanka K, Pharoah Paul DP, Michailidou Kyriaki, Dennis Joe, Bolla Manjeet K, Wang Qin, Van 't Veer Laura J, Cornelissen Sten, Rutgers Emiel, Southey Melissa C, Apicella Carmen, Dite Gillian S, Hopper John S, Fasching Peter A, Haeberle Lothar, Ekici Arif B et al. 2014. 2q36.3 is associated with prognosis for oestrogen receptor-negative breast cancer patients treated with chemotherapy. Nature Communications 5: 4051. 2014
• Khan Sofia, Greco Dari, Michailidou Kyriaki, Milne Roger L, Muranen Taru A, Heikkinen Tuomas, Aaltonen Kirsimari, Dennis Joe, Bolla Manjeet K, Liu Jianjun, Hall Per, Irwanto Astrid, Humphreys Keith, Li Jingmei, Czene Kamila, Chang-Claude Jenny, Hein Rebecca, Rudolp Anja, Seibold Petra, Flesch-Janys Dieter et at (including Kataja Vesa, Kosma Veli-Matti, Hartikainen Jaana M, Mannermaa Arto). 2014. MicroRNA Related Polymorphisms and Breast Cancer Risk. PLOS ONE [ONLINE] 9 11: e109973 (1-12). 2014
• Johnson Nichola, Dudbridge Frank, Orr Nick, Gibson Lorna, Jones Michael E, Schoemaker Minouk J, Folkerd Elizabeth J, Haynes Ben P, Hopper John L, Southey Melissa C, Dite Gillian S, Apicella Carmel, Schmidt Marjanka K, Broeks Annegien, Van T Veer Laura J, Atsma Femke et al. 2014. Genetic variation at CYP3A is associated with age at menarche and breast cancer risk: a case-control study. BREAST CANCER RESEARCH AND TREATMENT 16 3: R51. 2014
• Ghoussaini M, Edwards SL, Michailidou K, Nord S, Cowper-Sal Lari R, Desai K, Kar S, Hillman KM, Kaufmann S, Glubb DM, Beesley J, Dennis J, Bolla MK, Wang Q, Dicks E, Guo Q, Mannermaa A, Kataja V, Kosma VM, Hartikainen JM, et al.. 2014. Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation. Nature Communications 4: Article number:4999. 2014
• Agarwal D, Pineda S, Michailidou K, Herranz J, Pita G, Moreno LT, Mannermaa A, Kataja V, Kosma V-M, Hartikainen J, Easton DF, Pharoah PDP, Arias-Perez JI, Zamora P, Benitez J, Milne RL et.al. 2014. FGF receptor genes and breast cancer susceptibility: results from the Breast Cancer Association Consortium. BRITISH JOURNAL OF CANCER 110 4: 1088-1100. 2014
• Michailidou K, Hall P, Gonzalez-Neira A, Ghoussaini M, Dennis J, Milne RL, Schmidt MK, Chang-Claude J, Bojesen SE, Bolla MK, Wang Q, Dicks E, Lee A et. al. 2013. Large-scale genotyping identifies 41 new loci associated with breast cancer risk. NATURE GENETICS 45 4: 353-61. 2013
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