Jari Tiihonen
Professor
MD, PhD
Institute of Clinical Medicine, School of Medicine, Faculty of Health Sciences
jari.tiihonen@uef.fi
Office at Niuvanniemi Hospital (Niuvankuja 65, FI-70240 Kuopio, Finland)
Present positions
• Professor, University of Eastern Finland, School of Medicine, Institute of Clinical Medicine, Kuopio, Finland
• Professor, Karolinska Institutet, Department of Clinical Neuroscience, Stockholm, Sweden
Major research interests
• Psychiatry, psychopharmacology, functional brain imaging, autoradiography studies on dopamine and serotonin receptors and transporters in the human brain; epidemiology, genetics and neurobiology of substance dependence; violent and suicidal behavior
Research groups
Keywords
Publications
594/594 items-
Aggression hoidon psykofarmakologia
Lähteenvuo, Markku; Tiihonen, Jari. Teoksessa: Ahlgrén-Rimpiläinen, Aulikki; Seppänen, Allan; Melander, Sakari; Rautanen, Mika(toim.) , 2024. Oikeuspsykiatria. s. 322-327. Terveyden ja hyvinvoinnin laitos -
Aggression neurobiologia
Lähteenvuo, Markku; Tiihonen, Jari. Teoksessa: Ahlgrén-Rimpiläinen, Aulikki; Seppänen, Allan; Melander, Sakari; Rautanen, Mika(toim.) , 2024. Oikeuspsykiatria. s. 301-306. Terveyden ja hyvinvoinnin laitos -
Antipsychotic Use and Psychiatric Hospitalization in First-Episode Non-affective Psychosis and Cannabis Use Disorder: A Swedish Nationwide Cohort Study
Denissoff, Alexander; Taipale, Heidi; Tiihonen, Jari; Di Forti, Marta; Mittendorfer-Rutz, Ellenor; Tanskanen, Antti; Mustonen, Antti; Niemelä, Solja. 2024. Schizophrenia bulletin. [Epub ahead of print 26 Mar 2024]: 1-8 -
Association of antidepressant and benzodiazepine use, and anticholinergic burden with cognitive performance in schizophrenia
Mäkipelto, Ville; Tuulio-Henriksson, Annamari; Hakulinen, Christian; Niemelä, Solja; Lähteenvuo, Markku; Wegelius, Asko; Kieseppä, Tuula; Isometsä, Erkki; Tiihonen, Jari; Kampman, Olli; Lahdensuo, Kaisla; Mazumder, Atiqul; Suvisaari, Jaana; Holm, Minna. 2024. Schizophrenia research. 266: 118-126 -
Development and Validation of a Machine Learning–Based Model of Mortality Risk in First-Episode Psychosis
Lieslehto, Johannes; Tiihonen, Jari; Lähteenvuo, Markku; Leucht, Stefan; Correll, Christoph U.; Mittendorfer-Rutz, Ellenor; Tanskanen, Antti; Taipale, Heidi. 2024. JAMA network open. 7: -
Discontinuation of psychotropic medication: a synthesis of evidence across medication classes
Vinkers, Christiaan H; Kupka, Ralph W; Penninx, Brenda W; Ruhé, Henricus G; van Gaalen, Jakob M; van Haaren, Paul CF; Schellekens, Arnt FA; Jauhar, Sameer; Ramos-Quiroga, Josep A; Vieta, Eduard; Tiihonen, Jari; Veldman, Stijn E; Veling, Wim; Vis, Roeland; de Wit, Laura E; Luykx, Jurjen J. 2024. Molecular psychiatry. [Published: 19 March 2024]: 1-12 -
Efficacy and effectiveness of antipsychotics in schizophrenia: network meta-analyses combining evidence from randomised controlled trials and real-world data
Efthimiou, Orestis; Taipale, Heidi; Radua, Joaquim; Schneider-Thoma, Johannes; Pinzón-Espinosa, Justo; Ortuño, Maria; Vinkers, Christiaan H; Mittendorfer-Rutz, Ellenor; Cardoner, Narcís; Tanskanen, Antti; Fusar-Poli, Paolo; Cipriani, Andrea; Vieta, Eduard; Leucht, Stefan; Tiihonen, Jari; Luykx, Jurjen J. 2024. The Lancet Psychiatry. 11: 102-111 -
Genetic contribution to microglial activation in schizophrenia
Koskuvi, Marja; Pörsti, Elina; Hewitt, Tristen; Räsänen, Noora; Wu, Ying-Chieh; Trontti, Kalevi; McQuade, Amanda; Kalyanaraman, Shringaa; Ojansuu, Ilkka; Vaurio, Olli; Cannon, Tyrone D; Lönnqvist, Jouko; Therman, Sebastian; Suvisaari, Jaana; Kaprio, Jaakko; Blurton-Jones, Mathew; Hovatta, Iiris; Lähteenvuo, Markku; Rolova, Taisia; Lehtonen, Šárka; Tiihonen, Jari; Koistinaho, Jari. 2024. Molecular psychiatry. [Published: 22 March 2024]: 1-12 -
Navigated and individual α-peak-frequency–guided transcranial magnetic stimulation in male patients with treatment-refractory schizophrenia
Tuppurainen, Heli; Määttä, Sara; Könönen, Mervi; Julkunen, Petro; Kautiainen, Hannu; Hyvärinen, Soile; Vaurio, Olli; Joensuu, Mikko; Vanhanen, Matti; Aho-Mustonen, Kati; Mervaala, Esa; Tiihonen, Jari. 2024. Journal of psychiatry and neuroscience. 49: E87-E95 -
Psykoosisairaudet
Tiihonen, Jari; Lähteenvuo, Markku. Teoksessa: Ahlgrén-Rimpiläinen, Aulikki; Seppänen, Allan; Melander, Sakari; Rautanen, Mika(toim.) , 2024. Oikeuspsykiatria. s. 224-231. Terveyden ja hyvinvoinnin laitos -
Regional differences in mortality risk and in attenuating or aggravating factors in schizophrenia: A systematic review and meta-analysis
Solmi, Marco; Croatto, Giovanni; Fornaro, Michele; Schneider, Lynne Kolton; Rohani-Montez, S Christy; Fairley, Leanne; Smith, Nathalie; Bitter, István; Gorwood, Philip; Taipale, Heidi; Tiihonen, Jari; Cortese, Samuele; Dragioti, Elena; Rietz, Ebba Du; Nielsen, Rene Ernst; Firth, Joseph; Fusar-Poli, Paolo; Hartman, Catharina; Holt, Richard I G; Høye, Anne; Koyanagi, Ai; Larsson, Henrik; Lehto, Kelli; Lindgren, Peter; Manchia, Mirko; Nordentoft, Merete; Skonieczna-Żydecka, Karolina; Stubbs, Brendo. 2024. European neuropsychopharmacology. 80: 55-69 -
Relative Risk of Breast Cancer Associated With Prolactin-Increasing Antipsychotic Use
Taipale, Heidi; Solmi, Marco; Correll, Christoph U; Tiihonen, Jari. 2024. Journal of clinical psychiatry. 85: -
An international research agenda for clozapine-resistant schizophrenia
Luykx, Jurjen J.; Gonzalez-Diaz, Jairo M.; Guu, Ta Wei; van der Horst, Marte Z.; van Dellen, Edwin; Boks, Marco P.; Guloksuz, Sinan; DeLisi, Lynn E.; Sommer, Iris E.; Cummins, Russel; Shiers, David; Lee, Jimmy; Every-Palmer, Susanna; Mhalla, Ahmed; Chadly, Zohra; Chan, Sherry K.W.; Cotes, Robert O.; Takahashi, Shun; Benros, Michael E.; Wagner, Elias; Correll, Christoph U.; Hasan, Alkomiet; Siskind, Dan; Endres, Dominique; MacCabe, James; Tiihonen, Jari. 2023. The Lancet Psychiatry. 10: 644-652 -
Association of pharmacological treatments and real‐world outcomes in borderline personality disorder
Lieslehto, Johannes; Tiihonen, Jari; Lähteenvuo, Markku; Mittendorfer‐Rutz, Ellenor; Tanskanen, Antti; Taipale, Heidi. 2023. Acta psychiatrica scandinavica. 147: 603-613 -
Cause-specific excess mortality after first diagnosis of bipolar disorder: population-based cohort study
Paljärvi, Tapio; Herttua, Kimmo; Taipale, Heidi; Lähteenvuo, Markku; Tanskanen, Antti; Fazel, Seena; Tiihonen, Jari. 2023. BMJ mental health. 26: -
Cohort profile: SUPER-Finland – the Finnish study for hereditary mechanisms of psychotic disorders
Lähteenvuo, Markku; Ahola-Olli, Ari; Suokas, Kimmo; Holm, Minna; Misiewicz, Zuzanna; Jukuri, Tuomas; Männynsalo, Teemu; Wegelius, Asko; Haaki, Willehard; Kajanne, Risto; Kyttälä, Aija; Tuulio-Henriksson, Annamari; Lahdensuo, Kaisla; Häkkinen, Katja; Hietala, Jarmo; Paunio, Tiina; Niemi-Pynttäri, Jussi; Kieseppä, Tuula; Veijola, Juha; Lönnqvist, Jouko; Isometsä, Erkki; Kampman, Olli; Tiihonen, Jari; Hyman, Steven; Neale, Benjamin; Daly, Mark; Suvisaari, Jaana; Palotie, Aarno. 2023. BMJ open. 13: -
Comparative Effectiveness of Pharmacotherapies for the Risk of Attempted or Completed Suicide Among Persons With Borderline Personality Disorder
Lieslehto, Johannes; Tiihonen, Jari; Lähteenvuo, Markku; Mittendorfer-Rutz, Ellenor; Tanskanen, Antti; Taipale, Heidi. 2023. JAMA network open. 6: -
Effect of severity of depression on augmentation of antidepressant medication in young adults with depression
Lampela, Pasi; Tanskanen, Antti; Lähteenvuo, Markku; Tiihonen, Jari; Taipale, Heidi. 2023. Acta psychiatrica scandinavica. 2024; 49: 41-51 -
Effects of Substance Use and Antisocial Personality on Neuroimaging-Based Machine Learning Prediction of Schizophrenia
Taipale, Matias; Tiihonen, Jari; Korhonen, Juuso; Popovic, David; Vaurio, Olli; Lähteenvuo, Markku; Lieslehto, Johannes. 2023. Schizophrenia bulletin. 49: 1568-1578 -
Efficacy of immersive extended reality (XR) interventions on different symptom domains of schizophrenia spectrum disorders. A systematic review
Holopainen, Roope; Tiihonen, Jari; Lähteenvuo, Markku. 2023. Frontiers in psychiatry. 14: . 1208287 -
Functional Characterization of Six SLCO1B1 (OATP1B1) Variants Observed in Finnish Individuals with a Psychotic Disorder
Häkkinen, Katja; Kiander, Wilma; Kidron, Heidi; Lähteenvuo, Markku; Urpa, Lea; Lintunen, Jonne; Vellonen, Kati Sisko; Auriola, Seppo; Holm, Minna; Lahdensuo, Kaisla; Kampman, Olli; Isometsä, Erkki; Kieseppä, Tuula; Lönnqvist, Jouko; Suvisaari, Jaana; Hietala, Jarmo; Tiihonen, Jari; Palotie, Aarno; Ahola-Olli, Ari V.; Niemi, Mikko. 2023. Molecular pharmaceutics. 20: 1500-1508 -
General and violent recidivism of former forensic psychiatric patients in Finland
Ojansuu, Ilkka; Latvala, Antti; Kautiainen, Hannu; Forsman, Jonas; Tiihonen, Jari; Lähteenvuo, Markku. 2023. Frontiers in psychiatry. 14: . 1157171 -
Non-adherence to mood stabilizers and antipsychotics among persons with bipolar disorder-A nationwide cohort study
Lintunen, Jonne; Lahteenvuo, Markku; Tanskanen, Antti; Tiihonen, Jari; Taipale, Heidi. 2023. Journal of affective disorders. 333: 403-408 -
Real-world effectiveness of antidepressant use in persons with schizophrenia: within-individual study of 61,889 subjects
Puranen, Arto; Koponen, Marjaana; Lähteenvuo, Markku; Tanskanen, Antti; Tiihonen, Jari; Taipale, Heidi. 2023. Schizophrenia. 9: -
Real-world effectiveness of pharmacological treatments for bipolar disorder: Register-based national cohort study
Lähteenvuo, Markku; Paljärvi, Tapio; Tanskanen, Antti; Taipale, Heidi; Tiihonen, Jari. 2023. British journal of psychiatry. 223: 456-464 -
Real-world use of pharmacological treatments for incident bipolar disorder: A Finnish nationwide cohort study
Koistinaho, Aura; Poranen, Juulia; Tanskanen, Antti; Tiihonen, Jari; Taipale, Heidi; Lähteenvuo, Markku. 2023. Journal of affective disorders. 340: 237-244 -
Safety of Antipsychotic Polypharmacy Versus Monotherapy in a Nationwide Cohort of 61,889 Patients With Schizophrenia
Taipale, Heidi; Tanskanen, Antti; Tiihonen, Jari. 2023. American journal of psychiatry. 180: 377-385 -
Substance Use and Sleep Problems in Patients With Psychotic Disorders
Cederlöf, Erik; Holm, Minna; Ahti, Johan; Lähteenvuo, Markku; Hietala, Jarmo; Häkkinen, Katja; Isometsä, Erkki; Kampman, Olli; Lahdensuo, Kaisla; Lönnqvist, Jouko; Suvisaari, Jaana; Tiihonen, Jari; Wegelius, Asko; Veijola, Juha; Palotie, Aarno; Kieseppä, Tuula; Niemelä, Solja; Paunio, Tiina. 2023. Schizophrenia bulletin open. 4: . sgac073 -
The use of long-acting injectables in early-phase schizophrenia
Tiihonen, Jari. 2023. The Lancet Psychiatry. 10: 481-482 -
Use of antipsychotics and antidepressants in first‐episode psychotic depression: A nationwide register‐based study
Hamina, A; Paljärvi, T; Tanskanen, A; Lähteenvuo, M; Tiihonen, J; Taipale, H. 2023. Acta psychiatrica scandinavica. 148: 416-425 -
Validation of the Collaborative Outcomes study on Health and Functioning during Infection Times (COH-FIT) questionnaire for adults
Solmi, Marco; Thompson, Trevor; Estradé, Andrés; Agorastos, Agorastos; Radua, Joaquim; Cortese, Samuele; Dragioti, Elena; Leisch, Friedrich; Vancampfort, Davy; Thygesen, Lau Caspar; Aschauer, Harald; Schlögelhofer, Monika; Aschauer, Elena; Schneeberger, Andres; Huber, Christian G.; Hasler, Gregor; Conus, Philippe; Do Cuénod, Kim Q.; von Känel, Roland; Arrondo, Gonzalo; Fusar-Poli, Paolo; Gorwood, Philip; Llorca, Pierre-Michel; Krebs, Marie-Odile; Scanferla, Elisabetta; Kishimoto, Taishiro; Rabba. 2023. Journal of affective disorders. 326: 249-261 -
β2-Adrenoceptor Agonists in Asthma or Chronic Obstructive Pulmonary Disease and Risk of Parkinson’s Disease: Nested Case-Control Study
Paakinaho, Anne; Tiihonen, Miia; Koskela, Heikki; Koponen, Marjaana; Tiihonen, Jari; Hartikainen, Sirpa; Tolppanen, Anna-Maija. 2023. Clinical epidemiology. 15: 695-705 -
Aberrant motor contagion of emotions in psychopathy and high-functioning autism
Sun, Lihua; Lukkarinen, Lasse; Noppari, Tuomo; Nazari-Farsani, Sanaz; Putkinen, Vesa; Seppala, Kerttu; Hudson, Matthew; Tani, Pekka; Lindberg, Nina; Karlsson, Henry K.; Hirvonen, Jussi; Salomaa, Marja; Venetjoki, Niina; Lauerma, Hannu; Tiihonen, Jari; Nummenmaa, Lauri. 2022. Cerebral cortex. 2023; 33: 374-384 -
Allopurinol, dipyridamole and calcium channel blockers in the treatment of bipolar disorder – A nationwide cohort study
Lintunen, Jonne; Lähteenvuo, Markku; Tanskanen, Antti; Tiihonen, Jari; Taipale, Heidi. 2022. Journal of affective disorders. 313: 43-48 -
Antipsychotic Use and Risk of Low-Energy Fractures in People With Schizophrenia: A Nationwide Nested Case-Control Study in Finland
Solmi, Marco; Lähteenvuo, Markku; Correll, Christoph U; Tanskanen, Antti; Tiihonen, Jari; Taipale, Heidi. 2022. Schizophrenia bulletin. 2023; 49: 78-89 -
Association of Pharmacological Treatments and Hospitalization and Death in Individuals With Amphetamine Use Disorders in a Swedish Nationwide Cohort of 13 965 Patients
Heikkinen, Milja; Taipale, Heidi; Tanskanen, Antti; Mittendorfer-Rutz, Ellenor; Lähteenvuo, Markku; Tiihonen, Jari. 2022. JAMA psychiatry. 2023; 80: 31-39 -
Association of Treatment-Resistant Depression With Patient Outcomes and Health Care Resource Utilization in a Population-Wide Study
Lundberg, Johan; Cars, Thomas; Lööv, Sven-Åke; Söderling, Jonas; Sundström, Johan; Tiihonen, Jari; Leval, Amy; Gannedahl, Anna; Björkholm, Carl; Själin, Mikael; Hellner, Clara. 2022. JAMA psychiatry. 2023; 80: 167-175 -
Associations between antipsychotic use, substance use and relapse risk in patients with schizophrenia: real-world evidence from two national cohorts
Lähteenvuo, Markku; Luykx, Jurjen J.; Taipale, Heidi; Mittendorfer-Rutz, Ellenor; Tanskanen, Antti; Batalla, Albert; Tiihonen, Jari. 2022. British journal of psychiatry. 221: 758-765 -
Brain structural alterations in autism and criminal psychopathy
Noppari, Tuomo; Sun, Lihua; Lukkarinen, Lasse; Putkinen, Vesa; Tani, Pekka; Lindberg, Nina; Saure, Emma; Lauerma, Hannu; Tiihonen, Jari; Venetjoki, Niina; Salomaa, Marja; Rautio, Päivi; Hirvonen, Jussi; Salmi, Juha; Nummenmaa, Lauri. 2022. Neuroimage : clinical. 35: -
Clinical and societal burden of incident major depressive disorder: A population‐wide cohort study in Stockholm
Lundberg, Johan; Cars, Thomas; Lööv, Sven‐Åke; Söderling, Jonas; Tiihonen, Jari; Leval, Amy; Gannedahl, Anna; Björkholm, Carl; Själin, Mikael; Hellner, Clara. 2022. Acta psychiatrica scandinavica. 146: 51-63 -
Clozapine and the risk of haematological malignancies – Authors' reply
Tiihonen, Jari; Tanskanen, Antti; Bell, J Simon; Dawson, Jessica L; Kataja, Vesa; Taipale, Heidi. 2022. The Lancet Psychiatry. 9: 539-540 -
Comparative effectiveness of mood stabilizers and antipsychotics in the prevention of hospitalization after lithium discontinuation in bipolar disorder
Holm, M.; Tanskanen, A.; Lähteenvuo, M.; Tiihonen, J.; Taipale, H.. 2022. European neuropsychopharmacology. 61: 36-42 -
Courses of treatment and risk factors for treatment-resistant depression in Finnish primary and special healthcare: A nationwide cohort study
Lähteenvuo, Markku; Taipale, Heidi; Tanskanen, Antti; Rannanpää, Saara; Tiihonen, Jari. 2022. Journal of affective disorders. 308: 236-242 -
Differences in psychosocial functioning between psychotic disorders in the Finnish SUPER study
Ahti, Johan; Kieseppä, Tuula; Suvisaari, Jaana; Suokas, Kimmo; Holm, Minna; Wegelius, Asko; Ahola-Olli, Ari; Häkkinen, Katja; Kampman, Olli; Lähteenvuo, Markku; Paunio, Tiina; Tiihonen, Jari; Tuulio-Henriksson, Annamari; Isometsä, Erkki. 2022. Schizophrenia research. 244: 10-17 -
Effectiveness of Antipsychotic Use for Reducing Risk of Work Disability: Results From a Within-Subject Analysis of a Swedish National Cohort of 21,551 Patients With First-Episode Nonaffective Psychosis
Solmi, Marco; Taipale, Heidi; Holm, Minna; Tanskanen, Antti; Mittendorfer-Rutz, Ellenor; Correll, Christoph U.; Tiihonen, Jari. 2022. American journal of psychiatry. 179: 938-946 -
Factors and their weight in reducing life expectancy in schizophrenia
Correll, Christoph U.; Bitter, István; Hoti, Fabian; Mehtälä, Juha; Wooller, Annette; Pungor, Katalin; Tiihonen, Jari. 2022. Schizophrenia research. 250: 67-75 -
Female Psychopathy and Mortality
Vaurio, Olli; Lähteenvuo, Markku; Kautiainen, Hannu; Repo-Tiihonen, Eila; Tiihonen, Jari. 2022. Frontiers in psychiatry. 13: . 831410 -
Genome-wide association analyses of symptom severity among clozapine-treated patients with schizophrenia spectrum disorders
Okhuijsen-Pfeifer, C.; van der Horst, M. Z.; Bousman, C. A.; Lin, B.; van Eijk, K. R.; Ripke, S.; Ayhan, Y.; Babaoglu, M. O.; Bak, M.; Alink, W.; van Beek, H.; Beld, E.; Bouhuis, A.; Edlinger, M.; Erdogan, I. M.; Ertuğrul, A.; Yoca, G.; Everall, I. P.; Görlitz, T.; van Amelsvoort, T.; Bartels-Velthuis, A. A.; Bruggeman, R.; Cahn, W.; Guloksuz, S.; de Haan, L.; Kahn, R. S.; Schirmbeck, F.; Simons, C. J.P.; van Os, J.; Alizadeh, B. Z.; Luykx, J. J.; Rutten, B. P.F.; van Winkel, R.; Grootens, K. P.. 2022. Translational psychiatry. 12: . 145 -
Half a century of research on antipsychotics and schizophrenia: A scientometric study of hotspots, nodes, bursts, and trends
Sabe, Michel; Pillinger, Toby; Kaiser, Stefan; Chen, Chaomei; Taipale, Heidi; Tanskanen, Antti; Tiihonen, Jari; Leucht, Stefan; Correll, Christoph U.; Solmi, Marco. 2022. Neuroscience and biobehavioral reviews. 136: -
Healthcare utilization, costs, and productivity losses in treatment-resistant depression in Finland – a matched cohort study
Taipale, Heidi; Lähteenvuo, Markku; Tanskanen, Antti; Huoponen, Saara; Rannanpää, Saara; Tiihonen, Jari. 2022. Bmc psychiatry. 22: . 484 -
Implementation of CYP2D6 copy-number imputation panel and frequency of key pharmacogenetic variants in Finnish individuals with a psychotic disorder
Häkkinen, Katja; Kiiski, Johanna I; Lähteenvuo, Markku; Jukuri, Tuomas; Suokas, Kimmo; Niemi-Pynttäri, Jussi; Kieseppä, Tuula; Männynsalo, Teemu; Wegelius, Asko; Haaki, Willehard; Lahdensuo, Kaisla; Kajanne, Risto; Kaunisto, Mari A; Tuulio-Henriksson, Annamari; Kampman, Olli; Hietala, Jarmo; Veijola, Juha; Lönnqvist, Jouko; Isometsä, Erkki; Paunio, Tiina; Suvisaari, Jaana; Kalso, Eija; Niemi, Mikko; Tiihonen, Jari; Daly, Mark; Palotie, Aarno; Ahola-Olli, Ari V. 2022. Pharmacogenomics journal. 22: 166-172 -
Long-term treatment with clozapine and other antipsychotic drugs and the risk of haematological malignancies in people with schizophrenia: a nationwide case-control and cohort study in Finland
Tiihonen, Jari; Tanskanen, Antti; Bell, J Simon; Dawson, Jessica L; Kataja, Vesa; Taipale, Heidi. 2022. The Lancet Psychiatry. 9: 353-362 -
Lääkehoito voi vähentää psyykkisiin sairauksiin liittyvää ennenaikaista kuolleisuutta
Tiihonen, Jari. 2022. Lääkärilehti. 77: 1999 -
Mortality in people with schizophrenia: a systematic review and meta‐analysis of relative risk and aggravating or attenuating factors
Correll, Christoph U; Solmi, Marco; Croatto, Giovanni; Schneider, Lynne Kolton; Rohani‐Montez, S Christy; Fairley, Leanne; Smith, Nathalie; Bitter, István; Gorwood, Philip; Taipale, Heidi; Tiihonen, Jari. 2022. World psychiatry. 21: 248-271 -
Mortality in psychotic depression: 18-year follow-up study
Paljärvi, Tapio; Tiihonen, Jari; Lähteenvuo, Markku; Tanskanen, Antti; Fazel, Seena; Taipale, Heidi. 2022. British journal of psychiatry. 2023; 222: 37-43 -
Mu-opioid receptor system modulates responses to vocal bonding and distress signals in humans
Sun, Lihua; Lukkarinen, Lasse; Putkinen, Vesa; Karlsson, Henry K; Hirvonen, Jussi; Tiihonen, Jari; Lauerma, Hannu; Scott, Sophie; Nummenmaa, Lauri. 2022. Philosophical transactions of the Royal Society B: biological sciences. 377: . 20210181 -
Optimal Doses of Specific Antipsychotics for Relapse Prevention in a Nationwide Cohort of Patients with Schizophrenia
Taipale, Heidi; Tanskanen, Antti; Luykx, Jurjen J; Solmi, Marco; Leucht, Stefan; Correll, Christoph U; Tiihonen, Jari. 2022. Schizophrenia bulletin. 48: 774-784 -
Physical and mental health impact of COVID-19 on children, adolescents, and their families: The Collaborative Outcomes study on Health and Functioning during Infection Times - Children and Adolescents (COH-FIT-C&A)
Solmi, Marco; Estradé, Andrés; Thompson, Trevor; Agorastos, Agorastos; Radua, Joaquim; Cortese, Samuele; Dragioti, Elena; Leisch, Friedrich; Vancampfort, Davy; Thygesen, Lau Caspar; Aschauer, Harald; Schloegelhofer, Monika; Akimova, Elena; Schneeberger, Andres; Huber, Christian G.; Hasler, Gregor; Conus, Philippe; Cuénod, Kim Q. Do; von Känel, Roland; Arrondo, Gonzalo; Fusar-Poli, Paolo; Gorwood, Philip; Llorca, Pierre-Michel; Krebs, Marie-Odile; Scanferla, Elisabetta; Kishimoto, Taishiro; Rabba. 2022. Journal of affective disorders. 299: 367-376 -
Primary Nonadherence to Antipsychotic Treatment Among Persons with Schizophrenia
Lieslehto, Johannes; Tiihonen, Jari; Lähteenvuo, Markku; Tanskanen, Antti; Taipale, Heidi. 2022. Schizophrenia bulletin. 48: 655-663 -
Prolaktiinipitoisuutta suurentavat psykoosilääkkeet ja rintasyöpäriski rekisteritiedon valossa
Tiihonen, Jari; Kataja, Vesa; Lähteenvuo, Markku; Taipale, Heidi . 2022. Duodecim. 138: 296-298 -
Psychosis and the Risk of Stranger Homicides
Ojansuu, Ilkka; Lähteenvuo, Markku; Tiihonen, Jari; Lehti, Martti; Putkonen, Hanna. 2022. Schizophrenia bulletin open. 3: . sgac021 -
Psychotic depression and deaths due to suicide
Paljärvi, Tapio; Tiihonen, Jari; Lähteenvuo, Markku; Tanskanen, Antti; Fazel, Seena; Taipale, Heidi. 2022. Journal of affective disorders. 2023; 321: 28-32 -
Real-world effectiveness of antipsychotic doses for relapse prevention in patients with first-episode schizophrenia in Finland: a nationwide, register-based cohort study
Taipale, Heidi; Tanskanen, Antti; Correll, Christoph U; Tiihonen, Jari. 2022. The Lancet Psychiatry. 9: 271-279 -
Real-world effectiveness studies of low doses of antipsychotics – Authors' reply
Taipale, Heidi; Tanskanen, Antti; Correll, Christoph U; Tiihonen, Jari. 2022. The Lancet Psychiatry. 9: 536-537 -
Real‐world effectiveness of mood stabilizer use in schizophrenia
Puranen, Arto; Koponen, Marjaana; Lähteenvuo, Markku; Tanskanen, Antti; Tiihonen, Jari; Taipale, Heidi. 2022. Acta psychiatrica scandinavica. 2023; 147: 257-266 -
Real‐world effectiveness of pharmacological treatments of opioid use disorder in a national cohort
Heikkinen, Milja; Taipale, Heidi; Tanskanen, Antti; Mittendorfer‐Rutz, Ellenor; Lähteenvuo, Markku; Tiihonen, Jari. 2022. Addiction. 117: 1683-1691 -
Representation and Outcomes of Individuals With Schizophrenia Seen in Everyday Practice Who Are Ineligible for Randomized Clinical Trials
Taipale, Heidi; Schneider-Thoma, Johannes; Pinzón-Espinosa, Justo; Radua, Joaquim; Efthimiou, Orestis; Vinkers, Christiaan H; Mittendorfer-Rutz, Ellenor; Cardoner, Narcís; Pintor, Luis; Tanskanen, Antti; Tomlinson, Anneka; Fusar-Poli, Paolo; Cipriani, Andrea; Vieta, Eduard; Leucht, Stefan; Tiihonen, Jari; Luykx, Jurjen J. 2022. JAMA psychiatry. 79: 210-218 -
Sleep in Psychotic Disorders: Results From Nationwide SUPER Finland Study
Cederlöf, Erik; Holm, Minna; Lähteenvuo, Markku; Haaki, Willehard; Hietala, Jarmo; Häkkinen, Katja; Isometsä, Erkki; Jukuri, Tuomas; Kajanne, Risto; Kampman, Olli; Kieseppä, Tuula; Lahdensuo, Kaisla; Lönnqvist, Jouko; Männynsalo, Teemu; Niemi-Pynttäri, Jussi; Suokas, Kimmo; Suvisaari, Jaana; Tiihonen, Jari; Turunen, Hannu; Wegelius, Asko; Veijola, Juha; Palotie, Aarno; Paunio, Tiina. 2022. Schizophrenia bulletin open. 3: -
The collaborative outcomes study on health and functioning during infection times in adults (COH-FIT-Adults): Design and methods of an international online survey targeting physical and mental health effects of the COVID-19 pandemic
Solmi, Marco; Estradé, Andrés; Thompson, Trevor; Agorastos, Agorastos; Radua, Joaquim; Cortese, Samuele; Dragioti, Elena; Leisch, Friedrich; Vancampfort, Davy; Thygesen, Lau Caspar; Aschauer, Harald; Schloegelhofer, Monika; Akimova, Elena; Schneeberger, Andres; Huber, Christian G.; Hasler, Gregor; Conus, Philippe; Cuénod, Kim Q. Do; von Känel, Roland; Arrondo, Gonzalo; Fusar-Poli, Paolo; Gorwood, Philip; Llorca, Pierre-Michel; Krebs, Marie-Odile; Scanferla, Elisabetta; Kishimoto, Taishiro; Rabba. 2022. Journal of affective disorders. 299: 393-407 -
Twenty-year medication use trends in first-episode bipolar disorder
Poranen, Juulia; Koistinaho, Aura; Tanskanen, Antti; Tiihonen, Jari; Taipale, Heidi; Lähteenvuo, Markku. 2022. Acta psychiatrica scandinavica. 146: 583-593 -
Vuoden 2022 Matti Äyräpään palkinnon saaja Jari Tiihonen: Lääkehoitojen vaikuttavuustutkimus vie kohti dataohjautuvaa terveydenhuoltoa
Tiihonen, Jari. 2022. Duodecim. 138: 2091-2092 -
Women with Schizophrenia-Spectrum Disorders After Menopause: A Vulnerable Group for Relapse
Sommer, Iris E; Brand, Bodyl A; Gangadin, Shiral; Tanskanen, Antti; Tiihonen, Jari; Taipale, Heidi. 2022. Schizophrenia bulletin. 2023; 49: 136-143 -
Adenosine modulators and calcium channel blockers as add-on treatment for schizophrenia
Lintunen, Jonne; Lähteenvuo, Markku; Tiihonen, Jari; Tanskanen, Antti; Taipale, Heidi. 2021. NPJ schizophrenia. 7: 1 -
Antipsychotic Polypharmacy for the Management of Schizophrenia: Evidence and Recommendations
Lähteenvuo, Markku; Tiihonen, Jari. 2021. Drugs. 81: 1273-1284 -
Antipsychotic discontinuation: mind the patient and the real-world evidence
Luykx, Jurjen J; Tiihonen, Jari. 2021. The Lancet Psychiatry. 8: 555-557 -
Antipsychotic use and risk of breast cancer in women with schizophrenia: a nationwide nested case-control study in Finland
Taipale, Heidi; Solmi, Marco; Lähteenvuo, Markku; Tanskanen, Antti; Correll, Christoph U; Tiihonen, Jari. 2021. The Lancet Psychiatry. 8: 883-891 -
Antipsychotics Use Is Associated With Greater Adherence to Cardiometabolic Medications in Patients With Schizophrenia: Results From a Nationwide, Within-subject Design Study
Solmi, Marco; Tiihonen, Jari; Lähteenvuo, Markku; Tanskanen, Antti; Correll, Christoph U; Taipale, Heidi. 2021. Schizophrenia bulletin. 2022; 48: 166-175 -
Associations of age, sex, sexual abuse, and genotype with monoamine oxidase a gene methylation
Checknita, David; Tiihonen, Jari; Hodgins, Sheilagh; Nilsson, Kent W. 2021. Journal of neural transmission. 128: 1721-1739 -
Brain Basis of Psychopathy in Criminal Offenders and General Population
Nummenmaa, Lauri; Lukkarinen, Lasse; Sun, Lihua; Putkinen, Vesa; Seppälä, Kerttu; Karjalainen, Tomi; Karlsson, Henry K; Hudson, Matthew; Venetjoki, Niina; Salomaa, Marja; Rautio, Päivi; Hirvonen, Jussi; Lauerma, Hannu; Tiihonen, Jari. 2021. Cerebral cortex. 31: 4104-4114 -
Changes in the metabolic profile of human male postmortem frontal cortex and cerebrospinal fluid samples associated with heavy alcohol use
Kärkkäinen, Olli; Kokla, Marietta; Lehtonen, Marko; Auriola, Seppo; Martiskainen, Mika; Tiihonen, Jari; Karhunen, Pekka J.; Hanhineva, Kati; Kok, Eloise. 2021. Addiction biology. 26: e13035 -
Clozapine, Long-Acting Injectables (and Polypharmacy?) Superior in U.S. and International Registries
Leucht, Stefan; Tiihonen, Jari. 2021. American journal of psychiatry. 178: 888 - 889 -
Continuity of antipsychotic medication use among migrant and Finnish-born populations with a psychotic disorder: a register-based study
Lehti, Venla; Taipale, Heidi; Gissler, Mika; Tanskanen, Antti; Elonheimo, Martta; Tiihonen, Jari; Suvisaari, Jaana. 2021. Psychological medicine. [online 02 June 2021]: 1-11 -
Contribution of astrocytes to familial risk and clinical manifestation of schizophrenia
Koskuvi, Marja; Lehtonen, ¦árka; Trontti, Kalevi; Keuters, Meike; Wu, Ying-Chieh; Koivisto, Hennariikka; Ludwig, Anastasia; Plotnikova, Lidiia; Virtanen, Pekka LJ; Räsänen, Noora; Kaipainen, Satu; Hyötyläinen, Ida; Dhungana, Hiramani; Giniatullina, Raisa; Ojansuu, Ilkka; Vaurio, Olli; Cannon, Tyrone D; Lönnqvist, Jouko; Therman, Sebastian; Suvisaari, Jaana; Kaprio, Jaakko; Lähteenvuo, Markku; Tohka, Jussi; Giniatullin, Rashid; Rivera, Claudio; Hovatta, Iiris; Tanila, Heikki; Tiihonen, Jari; Koi. 2021. Glia. 2022; 70: 650-660 -
Correspondence regarding De Girolamo et al., 2021 'A multinational case-control study comparing forensic and non-forensic patients with schizophrenia spectrum disorders: the EU-VIORMED project'
Hodgins, Sheilagh; Eronen, Markku; Freese, Roland; Hart, Stephen; Mueller-Isberner, Ruediger; Ross, Deborah; Webster, Christopher; Tiihonen, Jari. 2021. Psychological medicine. Published online: 02 November 2021: 1 - 2 -
Effectiveness of pharmacotherapies for delusional disorder in a Swedish national cohort of 9076 patients
Lähteenvuo, Markku; Taipale, Heidi; Tanskanen, Antti; Mittendorfer-Rutz, Ellenor; Tiihonen, Jari. 2021. Schizophrenia research. 228: 367-372 -
Exploring the relation between high-activity COMT Val158Met genotype and psychopathy in male offenders
Pauli, Malin; Ölund Alonso, Hannibal; Liljeberg, Jenny; Gustavsson, Petter; Tiihonen, Jari; Howner, Katarina. 2021. Journal of forensic psychiatry and psychology. 2022; 33: 172-177 -
HLA-DQB1 6672G>C (rs113332494) is associated with clozapine-induced neutropenia and agranulocytosis in individuals of European ancestry
Konte, Bettina; Walters, James TR; Rujescu, Dan; Legge, Sophie E; Pardiñas, Antonio F; Cohen, Dan; Pirmohamed, Munir; Tiihonen, Jari; Hartmann, Annette M; Bogers, Jan P; van der Weide, Jan; van der Weide, Karen; Putkonen, Anu; Repo-Tiihonen, Eila; Hallikainen, Tero; Silva, Ed; Ingimarsson, Oddur; Sigurdsson, Engilbert; Kennedy, James L; Sullivan, Patrick F et al.. 2021. Translational psychiatry. 11: 214 -
Hip Fracture Risk in Antiepileptic Drug Initiators and Non-Initiators with Alzheimer's Disease
Pisa, Federica; Reinold, Jonas; Lavikainen, Piia; Koponen, Marjaana; Taipale, Heidi; Tanskanen, Antti; Tiihonen, Jari; Hartikainen, Sirpa; Tolppanen, Anna-Maija. 2021. Clinical epidemiology. 13: 295-307 -
Incidence of schizophrenia and influence of prenatal and infant exposure to viral infectious diseases
Tanskanen, Antti; Taipale, Heidi; Cannon, Mary; Cotter, David; Tiihonen, Jari. 2021. Acta psychiatrica scandinavica. 143: 487-494 -
Long-Term Real-World Effectiveness of Pharmacotherapies for Schizoaffective Disorder
Lintunen, Jonne; Taipale, Heidi; Tanskanen, Antti; Mittendorfer-Rutz, Ellenor; Tiihonen, Jari; Lähteenvuo, Markku. 2021. Schizophrenia bulletin. 47: 1099-1107 -
Long-term Continuity of Antipsychotic Treatment for Schizophrenia: A Nationwide Study
Rubio, Jose M; Taipale, Heidi; Tanskanen, Antti; Correll, Christoph U; Kane, John M; Tiihonen, Jari. 2021. Schizophrenia bulletin. 47: 1611-1620 -
Molecular signaling pathways underlying schizophrenia
Tiihonen, Jari; Koskuvi, Marja; Lähteenvuo, Markku; Trontti, Kalevi; Ojansuu, Ilkka; Vaurio, Olli; Cannon, Tyrone D; Lönnqvist, Jouko; Therman, Sebastian; Suvisaari, Jaana; Cheng, Lesley; Tanskanen, Antti; Taipale, Heidi; Lehtonen, ¦árka; Koistinaho, Jari. 2021. Schizophrenia research. 232: 33-41 -
Morbidity and mortality in schizophrenia with comorbid substance use disorders
Lähteenvuo, Markku; Batalla, Albert; Luykx, Jurjen J; Mittendorfer-Rutz, Ellenor; Tanskanen, Antti; Tiihonen, Jari; Taipale, Heidi. 2021. Acta psychiatrica scandinavica. 144: 42-49 -
Oikeuspsykiatria
Tiihonen, Jari. Teoksessa: Lönnqvist, Jouko; Henriksson, Markus; Marttunen, Mauri; Partonen, Timo(toim.) , 2021. Psykiatria (15. uudistettu painos). s. 825-843. Duodecim -
Päihdekäyttö ja riski syyllistyä muita vaarantaviin tekoihin
Tiihonen, Jari; Ojansuu, Ilkka; Lehti, Martti. 2021. Duodecim. 137: 2461-2466 -
Reaction Time and Visual Memory in Connection to Alcohol Use in Persons with Bipolar Disorder
Mazumder, Atiqul Haq; Barnett, Jennifer; Isometsä, Erkki Tapio; Lindberg, Nina; Torniainen-Holm, Minna; Lähteenvuo, Markku; Lahdensuo, Kaisla; Kerkelä, Martta; Ahola-Olli, Ari; Hietala, Jarmo; Kampman, Olli; Kieseppä, Tuula; Jukuri, Tuomas; Häkkinen, Katja; Cederlöf, Erik; Haaki, Willehard; Kajanne, Risto; Wegelius, Asko; Männynsalo, Teemu; Niemi-Pynttäri, Jussi [incl. Tiihonen, Jari]. 2021. Brain sciences. 11: 1154 -
Reaction Time and Visual Memory in Connection to Hazardous Drinking Polygenic Scores in Schizophrenia, Schizoaffective Disorder and Bipolar Disorder
Mazumder, Atiqul Haq; Barnett, Jennifer; Isometsä, Erkki Tapio; Lindberg, Nina; Torniainen-Holm, Minna; Lähteenvuo, Markku; Lahdensuo, Kaisla; Kerkelä, Martta; Ahola-Olli, Ari; Hietala, Jarmo; Kampman, Olli; Kieseppä, Tuula; Jukuri, Tuomas; Häkkinen, Katja; Cederlöf, Erik; Haaki, Willehard; Kajanne, Risto; Wegelius, Asko; Männynsalo, Teemu; Niemi-Pynttäri, Jussi; Suokas, Kimmo; Lönnqvist, Jouko; Tiihonen, Jari; Paunio, Tiina; Vainio, Seppo Juhani; Palotie, Aarno; Niemelä, Solja; Suvisaari, Jaana. 2021. Brain sciences. 11: 1422 -
Reaction Time and Visual Memory in Connection with Alcohol Use in Schizophrenia and Schizoaffective Disorder
Mazumder, Atiqul Haq; Barnett, Jennifer; Lindberg, Nina; Torniainen-Holm, Minna; Lähteenvuo, Markku; Lahdensuo, Kaisla; Kerkelä, Martta; Hietala, Jarmo; Isometsä, Erkki Tapio; Kampman, Olli; Kieseppä, Tuula; Jukuri, Tuomas; Häkkinen, Katja; Cederlöf, Erik; Haaki, Willehard; Kajanne, Risto; Wegelius, Asko; Männynsalo, Teemu; Niemi-Pynttäri, Jussi; Suokas, Kimmo; et al [incl. Tiihonen, Jari]. 2021. Brain sciences. 11: 688 -
Real-world effectiveness of pharmacological treatments of alcohol use disorders in a Swedish nation-wide cohort of 125-556 patients
Heikkinen, Milja; Taipale, Heidi; Tanskanen, Antti; Mittendorfer-Rutz, Ellenor; Lähteenvuo, Markku; Tiihonen, Jari. 2021. Addiction. 116: 1990-1998 -
Registry-based studies: What they can tell us, and what they cannot
Taipale, Heidi; Tiihonen, Jari. 2021. European neuropsychopharmacology. 45: 35-37 -
Risk Factors, Incidence, and Outcomes of Neuroleptic Malignant Syndrome on Long-Acting Injectable vs Oral Antipsychotics in a Nationwide Schizophrenia Cohort
Guinart, Daniel; Taipale, Heidi; Rubio, Jose M; Tanskanen, Antti; Correll, Christoph U; Tiihonen, Jari; Kane, John M. 2021. Schizophrenia bulletin. 47: 1621-1630 -
Risk of labour market marginalisation among young refugees and non-refugee migrants with common mental disorders
Di Thiene, D; Helgesson, Magnus; Rahman, S; Alexanderson, K; Tiihonen, J; La Torre, G; Mittendorfer-Rutz, E. 2021. Social psychiatry and psychiatric epidemiology. 56: 1024-1034 -
Switches and early discontinuations of antidepressant medication in young adults with depression
Lampela, Pasi; Tanskanen, Antti; Lähteenvuo, Markku; Tiihonen, Jari; Taipale, Heidi. 2021. Journal of affective disorders. 295: 1474-1481 -
The iPSC perspective on schizophrenia
Räsänen, Noora; Tiihonen, Jari; Koskuvi, Marja; Lehtonen, ¦árka; Koistinaho, Jari. 2021. Trends in neurosciences. 2022; 41: 8-26 -
Vaarallisuden ja väkivaltariskin arvioiminen
Tolvanen, Matti; Keski-Valkama, Alice; Koskela, Tarja; Pajuoja, Jussi; Rautanen, Mika; Tiihonen, Jari; Tyni, Sasu; Törölä, Miisa; Eskelinen, Emilia. 2021. Valtioneuvoston selvitys- ja tutkimustoiminnan julkaisusarja. . -
Vaarallisuuden ja väkivaltariskin arvioiminen
Tolvanen, Matti; Keski-Valkama, Alice; Koskela, Tarja; Pajuoja, Jussi; Rautanen, Mika; Tiihonen, Jari; Tyni, Sasu; Törölä, Miisa; Eskelinen, Emilia. 2021. Valtioneuvoston selvitys- ja tutkimustoiminnan julkaisusarja. . -
Voluntary patient safety incidents reporting in forensic psychiatry - What do the reports tell us?
Kuosmanen, Anssi; Tiihonen, Jari; Repo-Tiihonen, Eila; Turunen, Hannele. 2021. Journal of psychiatric and mental health nursing. 2022; 29: 36-47 -
20-year follow-up study of physical morbidity and mortality in relationship to antipsychotic treatment in a nationwide cohort of 62,250 patients with schizophrenia (FIN20)
Taipale, H; Tanskanen, A; Mehtälä, J; Vattulainen, P; Correll, CU; Tiihonen, J. 2020. World psychiatry. 19: 61-68 -
A Systematic Literature Review of Neuroimaging of Psychopathic Traits
Johanson, Mika; Vaurio, Olli; Tiihonen, Jari; Lähteenvuo, Markku. 2020. Frontiers in psychiatry. 10: 1027 -
Antiepileptic drug use and mortality among community-dwelling persons with Alzheimer disease
Sarycheva, Tatyana; Lavikainen, Piia; Taipale, Heidi; Tiihonen, Jari; Tanskanen, Antti; Hartikainen, Sirpa; Tolppanen, Anna-Maija. 2020. Neurology. 94: e2099-e2108 -
Antipsychotic use among persons with schizophrenia in Sweden and Finland, trends and differences
Taipale, Heidi; Puranen, Arto; Mittendorfer-Rutz, Ellenor; Tiihonen, Jari; Tanskanen, Antti; Cervenka, Simon; Lähteenvuo, Markku. 2020. Nordic journal of psychiatry. 2021; 75: 315-322 -
Asthma and Chronic Obstructive Pulmonary Disease as a Comorbidity and Association with the Choice of Antidementia Medication Among Persons with Alzheimer's Disease
Lampela, P; Tolppanen, AM; Koponen, M; Tanskanen, A; Tiihonen, J; Hartikainen, S; Taipale, H. 2020. Journal of Alzheimer's disease. 73: 1243-1251 -
Causes of death in a nationwide cohort of community-dwellers with Alzheimer's disease
Tolppanen, Anna-Maija; Taipale, Heidi; Koponen, Marjaana; Tiihonen, Jari; Hartikainen, Sirpa. 2020. Bmc geriatrics. 20: 441 -
Commentary on Robert Whitaker's viewpoint
Tiihonen, Jari; Taipale, Heidi; Correll, Christoph U. 2020. Psychological medicine. 50: 2653-2654 -
Comparative Effectiveness of Antipsychotics for Risk of Attempted or Completed Suicide Among Persons With Schizophrenia
Taipale, Heidi; Lähteenvuo, Markku; Tanskanen, Antti; Mittendorfer-Rutz, Ellenor; Tiihonen, Jari. 2020. Schizophrenia bulletin. 2021; 47: 23-30 -
Concordance and discordance in how patients and therapists experience the psychotherapy process in the treatment of depression
Ahola, Pasi; Härkänen, Tommi; Lehtonen, Johannes; Lindfors, Olavi; Knekt, Paul; Joensuu, Mikko; Saarinen, Pirjo; Tolmunen, Tommi; Virtala, Esa; Tiihonen, Jari; Valkonen-Korhonen, Minna. 2020. Psychiatria Fennica. 51: 122-141 -
Detection of medications associated with Alzheimer's disease using ensemble methods and cooperative game theory
Braithwaite, B; Paananen, J; Taipale, H; Tanskanen, A; Tiihonen, J; Hartikainen, S; Tolppanen, A-M. 2020. International journal of medical informatics. 141: 104142 -
Employment among people with schizophrenia or bipolar disorder: a population-based study using nationwide registers
Holm, Minna; Taipale, Heidi; Tanskanen, Antti; Tiihonen, Jari; Mitterdorfer-Rutz, Ellenor. 2020. Acta psychiatrica scandinavica. 2021; 143: 61-71 -
Health and Work Disability Outcomes in Parents of Patients With Schizophrenia Associated With Antipsychotic Exposure by the Offspring
Taipale, H; Rahman, S; Tanskanen, A; Mehtälä, J; Hoti, F; Jedenius, E; Enkusson, D; Leval, A; Sermon, J; Tiihonen, J; Mittendorfer-Rutz, E. 2020. Scientific reports. 10: 1219 -
In the aftermath of clozapine discontinuation: comparative effectiveness and safety of antipsychotics in patients with schizophrenia who discontinue clozapine
Luykx, JJ; Stam, N; Tanskanen, A; Tiihonen, J; Taipale, H. 2020. British journal of psychiatry. 217: 498-505 -
Incidence of and Characteristics Associated With Long-term Benzodiazepine Use in Finland
Taipale, Heidi; Särkilä, Hanna; Tanskanen, Antti; Kurko, Terhi; Taiminen, Tero; Tiihonen, Jari; Sund, Reijo; Tuulio-Henriksson, Annamari; Saastamoinen, Leena; Hietala, Jarmo. 2020. JAMA network open. 3: e2019029 -
Length of hospital stay for hip fracture and 30-day mortality in people with Alzheimer's disease: a cohort study in Finland
Lavikainen, Piia; Koponen, Marjaana; Taipale, Heidi; Tanskanen, Antti; Tiihonen, Jari; Hartikainen, Sirpa; Tolppanen, Anna-Maija. 2020. Journals of gerontology series a: biological sciences and medical sciences. 75: 2184-2192 -
Medication Use and Health Care Utilization After a Cost-sharing Increase in Schizophrenia: A Nationwide Analysis
Hamina, Aleksi; Tanskanen, Antti; Tiihonen, Jari; Taipale, Heidi. 2020. Medical care. 58: 763-769 -
Medication management of antipsychotic treatment in schizophrenia-A narrative review
Isohanni, Matti; Jääskeläinen, Erika; Miller, Brian J; Hulkko, Anja; Tiihonen, Jari; Möller, Hans-Jurgen; Hartikainen, Sirpa; Huhtaniska, Sanna; Lieslehto, Johannes. 2020. Human psychopharmacology: clinical and experimental. 2021; 36: e2765 -
Metformin and risk of Alzheimer's disease among community-dwelling people with diabetes: a national case-control study
Sluggett, JK; Koponen, M; Bell, JS; Taipale, H; Tanskanen, A; Tiihonen, J; Uusitupa, M; Tolppanen, AM; Hartikainen, S. 2020. Journal of clinical endocrinology and metabolism. 105: dgz234 -
Monoamine oxidase A genotype and methylation moderate the association of maltreatment and aggressive behaviour
Checknita, D; Bendre, M; Ekström, TJ; Comasco, E; Tiihonen, J; Hodgins, S; Nilsson, KW. 2020. Behavioural brain research. 382: 112476 -
Persistence of Antipsychotic Use After Clozapine Discontinuation: A Real-World Study Across Antipsychotics
Stam, Noraly; Taipale, Heidi; Tanskanen, Antti; Isphording, Luka; Okhuijsen-Pfeifer, Cynthia; Schuiling-Veninga, Catharina; Bos, Jens H; Bijker, Bert; Tiihonen, Jari; Luykx, Jurjen. 2020. Cts: clinical and translational science. 13: 1170-1177 -
Prevalence of cardiovascular drug use before and after diagnosis of Alzheimer's disease
Vu, Mai; Koponen, Marjaana; Taipale, Heidi; Tanskanen, Antti; Tiihonen, Jari; Kettunen, Raimo; Hartikainen, Sirpa; Tolppanen, Anna-Maija. 2020. International journal of cardiology. 300: 221-225 -
Psychosis relapse during treatment with long-acting injectable antipsychotics in individuals with schizophrenia-spectrum disorders: an individual participant data meta-analysis
Rubio, Jose M; Schoretsanitis, Georgios; John, Majnu; Tiihonen, Jari; Taipale, Heidi; Guinart, Daniel; Malhotra, Anil K; Correll, Christoph U; Kane, John M. 2020. The Lancet Psychiatry. 7: 749-761 -
Psykoosilääkkeiden käyttö on pitkäkestoista Alzheimerin tautia sairastavilla
Liehu, Maija; Tiihonen, Miia; Taipale, Heidi; Tanskanen, Antti; Tiihonen, Jari; Tolppanen, Anna-Maija; Hartikainen, Sirpa; Koponen, Marjaana. 2020. Dosis. 36: 6-23 -
Psyykenlääkkeet ja sydän
Kettunen, Raimo; Suvisaari, Jaana; Tiihonen, Jari; Ruskoaho, Heikki; Huikuri, Heikki. 2020. Duodecim. 136: 1411-1418 -
Rejoinder to rejoinder to commentary
Tiihonen, Jari; Taipale, Heidi; Correll, Christoph U.. 2020. Psychological medicine. 50: 2812-2813 -
Risk and risk factors for disability pension among patients with treatment resistant depression- a matched cohort study
Taipale, Heidi; Reutfors, Johan; Tanskanen, Antti; Brandt, Lena; Tiihonen, Jari; DiBernardo, Allitia; Mittendorfer-Rutz, Ellenor; Brenner, Philip. 2020. Bmc psychiatry. 20: 232 -
Suicide mortality and use of psychotropic drugs in patients hospitalized due to bipolar disorder: A Finnish nationwide cohort study
Antolín-Concha, Diego; Lähteenvuo, Markku; Vattulainen, Pia; Tanskanen, Antti; Taipale, Heidi; Vieta, Eduard; Tiihonen, Jari. 2020. Journal of affective disorders. 277: 885-892 -
The Risk of Head Injuries Associated With Antipsychotic Use Among Persons With Alzheimer's disease
Tapiainen, V; Lavikainen, P; Koponen, M; Taipale, H; Tanskanen, A; Tiihonen, J; Hartikainen, S; Tolppanen, AM. 2020. Journal of the american geriatrics society. 68: 595-602 -
The clinical course of schizophrenia in women and men-a nation-wide cohort study
Sommer, Iris E; Tiihonen, Jari; van Mourik, Anouk; Tanskanen, Antti; Taipale, Heidi. 2020. NPJ schizophrenia. 6: 12 -
Use of antidepressants and mood stabilizers in persons with first-episode schizophrenia
Puranen, Arto; Koponen, Marjaana; Tanskanen, Antti; Tiihonen, Jari; Taipale, Heidi. 2020. European journal of clinical pharmacology. 76: 711-718 -
Vaarallisuuden arviointi - sattuman summaako?
Ahlgrén-Rimpiläinen, Aulikki; Joelsson, Petteri; Kaarre, Hanna; Rautanen, Mika; Niinistö, Kirsi; Lindberg, Nina; Tiihonen, Jari. 2020. Edilex. : 1-30 -
Valproate and Neuroleptic Malignant Syndrome in an Elderly Patient With Schizoaffective Disorder
Lindeman, Sari; Kolari, Tuukka; Tiihonen, Jari. 2020. The primary care companion for cns disorders. 22: 19l02542 -
Accumulation of Hospital Days Among Antipsychotic Initiators With Alzheimer's Disease
Koponen, Marjaana; Lavikainen, Piia; Taipale, Heidi; Tanskanen, Antti; Tiihonen, Jari; Hartikainen, Sirpa; Tolppanen, Anna-Maija. 2019. Journal of the american medical directors association. 20: 1488-1494.e3 -
Adherence to psychotropic medication in completed suicide in Sweden 2006-2013: a forensic-toxicological matched case-control study
Forsman, J; Taipale, H; Masterman, T; Tiihonen, J; Tanskanen, A. 2019. European journal of clinical pharmacology. 75: 1421-1430 -
Alzheimer-potilaat ja psyykenlääkkeiden käyttö 2005-2011
Juhola, Laura; Taipale, Heidi; Koponen, Marjaana; Tanskanen, Antti; Tiihonen, Jari; Hartikainen, Sirpa; Tolppanen, Anna-Maija. 2019. Lääkärilehti. 74: 609-616 -
Antiepileptic Drug Use Is Associated with an Increased Risk of Pneumonia Among Community-Dwelling Persons with Alzheimer's Disease-Matched Cohort Study
Taipale, H; Lampela, P; Koponen, M; Tanskanen, A; Tiihonen, J; Hartikainen, S; Tolppanen, AM. 2019. Journal of Alzheimer's disease. 68: 127-136 -
Antiepileptic Drugs and Accumulation of Hospital Days Among Persons With Alzheimer's Disease
Lavikainen, Piia; Taipale, Heidi; Tanskanen, Antti; Koponen, Marjaana; Tiihonen, Jari; Hartikainen, Sirpa; Tolppanen, Anna-Maija. 2019. Journal of the american medical directors association. 20: 751-758 -
Association of Antipsychotic Polypharmacy vs Monotherapy With Psychiatric Rehospitalization Among Adults With Schizophrenia
Tiihonen, J; Taipale, H; Mehtälä, J; Vattulainen, P; Correll, CU; Tanskanen, A. 2019. JAMA psychiatry. 76: 499-507 -
Changes in Patient Safety Culture: A Patient Safety Intervention for Finnish Forensic Psychiatric Hospital Staff
Kuosmanen, A; Tiihonen, J; Repo-Tiihonen, E; Eronen, M; Turunen, H. 2019. Journal of nursing management. 27: 848-857 -
Hospital-Treated Pneumonia Associated with Opioid Use Among Community Dwellers with Alzheimer's Disease
Hamina, A; Taipale, H; Karttunen, N; Tanskanen, A; Tiihonen, J; Tolppanen, AM; Hartikainen, S. 2019. Journal of Alzheimer's disease. 69: 807-816 -
Incidence of head injury and traumatic brain injury among people with Alzheimer's disease
Ilmaniemi, S; Taipale, H; Tanskanen, A; Tiihonen, J; Hartikainen, S; Tolppanen, AM. 2019. Journal of epidemiology and community health. 73: 451-454 -
Increased [³H]quisqualic acid binding density in the dorsal striatum and anterior insula of alcoholics: A post-mortem whole-hemisphere autoradiography study
Laukkanen, V; Kärkkäinen, O; Kautiainen, H; Tiihonen, J; Storvik, M. 2019. Psychiatry research: neuroimaging. 287: 63-69 -
Long-acting injectable antipsychotics (LAIs) for maintenance treatment of bipolar and schizoaffective disorders: A systematic review
Pacchiarotti, I; Tiihonen, J; Kotzalidis, GD; Verdolini, N; Murru, A; Goikolea, JM; Valentí, M; Aedo, A; Vieta, E. 2019. European neuropsychopharmacology. 29: 457-470 -
Long-term thiazide use and risk of low-energy fractures among persons with Alzheimer's disease-nested case-control study
Taipale, H; Rysä, J; Hukkanen, J; Koponen, M; Tanskanen, A; Tiihonen, J; Kröger, H; Hartikainen, S; Tolppanen, AM. 2019. Osteoporosis international. 30: 1481-1489 -
Manifesto for an international digital mental health network
Maron, Eduard; Baldwin, David S; Balõt¨ev, Roman; Fabbri, Chiara; Gaur, Vikas; Hidalgo-Mazzei, Diego; Hood, Sean; Juhola, Martti; Kampman, Olli; Kasper, Siegfried; Kärkkäinen, Hilkka; Látalová, Klára; Lähteenvuo, Markku; Mastellos, Nikolas; McTigue, Joseph; Metsallik, Janek; Metspalu, Andres; Nutt, David; Nykänen, Pirkko; Olisa, Nigel et al. (incl. Tiihonen, Jari). 2019. Digital psychiatry. 2: 14-24 -
Neurobiological roots of psychopathy
Tiihonen, J; Koskuvi, M; Lähteenvuo, M; Virtanen, PLJ; Ojansuu, I; Vaurio, O; Gao, Y; Hyötyläinen, I; Puttonen, KA; Repo-Tiihonen, E; Paunio, T; Rautiainen, MR; Tyni, S; Koistinaho, J; Lehtonen, S. 2019. Molecular psychiatry. [Epub ahead of print 27 Aug 2019]: 1-10 -
Opioid Use After Hospital Care due to Hip Fracture Among Community-Dwelling Persons With and Without Alzheimer's Disease
Lintula, E; Tiihonen, M; Taipale, H; Tolppanen, AM; Tanskanen, A; Tiihonen, J; Hartikainen, S; Hamina, A. 2019. Drugs and aging. 2020; 37: 193-203 -
Predictors of high hospital care and medication costs and cost trajectories in community-dwellers with Alzheimer's disease
Kalamägi, J; Lavikainen, P; Taipale, H; Tanskanen, A; Tiihonen, J; Hartikainen, S; Tolppanen, AM. 2019. Annals of medicine. 51: 294-305 -
Psychosis breakthrough on antipsychotic maintenance: results from a nationwide study
Rubio, JM; Taipale, H; Correll, CU; Tanskanen, A; Kane, JM; Tiihonen, J. 2019. Psychological medicine. [Epub ahead of print 13 June 2019]: 1-12 -
Sex-specific transcriptional and proteomic signatures in schizophrenia
Tiihonen, J; Koskuvi, M; Storvik, M; Hyötyläinen, I; Gao, Y; Puttonen, KA; Giniatullina, R; Poguzhelskaya, E; Ojansuu, I; Vaurio, O; Cannon, TD; Lönnqvist, J; Therman, S; Suvisaari, J; Kaprio, J; Cheng, L; Hill, AF; Lähteenvuo, M; Tohka, J; Giniatullin, R; et al.. 2019. Nature communications. 10: 3933 -
Skitsofrenian lääkehoito
Tiihonen, Jari. 2019. Duodecim. 135: 2021-2027 -
Substance Abuse and Excessive Mortality Among Forensic Psychiatric Patients: A Finnish Nationwide Cohort Study
Ojansuu, Ilkka; Putkonen, Hanna; Lähteenvuo, Markku; Tiihonen, Jari. 2019. Frontiers in psychiatry. 10: 678 -
Trajectories of sickness absence, disability pension and unemployment in young immigrants with common mental disorders
Di Thiene, D; Mittendorfer-Rutz, E; Rahman, S; Wang, M; Alexanderson, K; Tiihonen, J; La Torre, G; Helgesson, M. 2019. European journal of public health. 29: 1055-1062 -
20-Year Nationwide Follow-Up Study on Discontinuation of Antipsychotic Treatment in First-Episode Schizophrenia
Tiihonen, Jari; Tanskanen, Antti; Taipale, Heidi. 2018. American journal of psychiatry. 175: 765-7731-9 -
Amygdala-orbitofrontal structural and functional connectivity in females with anxiety disorders, with and without a history of conduct disorder
Lindner, P; Flodin, P; Larm, P; Budhiraja, M; Savic-Berglund, I; Jokinen, J; Tiihonen, J; Hodgins, S. 2018. Scientific reports. 8: 1101 -
Antiepileptic Drug Use and the Risk of Stroke Among Community-Dwelling People With Alzheimer Disease: A Matched Cohort Study
Sarycheva, Tatyana; Lavikainen, Piia; Taipale, Heidi; Tiihonen, Jari; Tanskanen; Antti; Hartikainen, Sirpa; Tolppanen, Anna-Maija. 2018. Journal of the american heart association: Cardiovascular and cerebrovascular disease. 7: e009742 -
Antipsychotic Use and the Risk of Initiating Medication for Benign Prostate Hyperplasia in Persons With Alzheimer Disease: A Matched Cohort Study
Orsel, Kim; Taipale, Heidi; Raatikainen, Sami; Lampela, Pasi; Tolppanen, Anna-Maija; Koponen, Marjaana; Tanskanen, Antti; Tiihonen, Jari; Gardarsdottir, Helga; Hartikainen, Sirpa. 2018. Journal of clinical psychopharmacology. 38: 494-497 -
Antipsychotics and mortality in a nationwide cohort of 29,823 patients with schizophrenia
Taipale, Heidi; Mittendorfer-Rutz, Ellenor; Alexanderson, Kristina; Majak, Maila; Mehtälä, Juha; Hoti, Fabian; Jedenius, Erik; Enkusson, Dana; Leval, Amy; Sermon, Jan; Tanskanen, Antti; Tiihonen, Jari. 2018. Schizophrenia research. 197: 274-280 -
Associations between MAOA-uVNTR genotype, maltreatment, MAOA methylation and alcohol consumption in young adult males
Bendre, Megha; Comasco, Erika; Checknita, Dave; Tiihonen, Jari; Hodgins, Sheilagh; Nilsson, Kent W. 2018. Alcoholism-clinical and experimental research. 42: 508-519 -
Associations of Psychopathic Traits With Local and Global Brain Network Topology in Young Adult Women
Lindner, Philip; Flodin, Pär; Budhiraja, Meenal; Savic, Ivanka; Jokinen, Jussi; Tiihonen, Jari; Hodgins, Sheilagh. 2018. Biological psychiatry : cognitive neuroscience and neuroimaging. 3: 1003-1012 -
Associations of monoamine oxidase A gene first exon methylation with sexual abuse and current depression in women
Checknita, David; Ekström, Tomas J; Comasco, Erika; Nilsson, Kent W; Tiihonen, Jari; Hodgins, Sheilagh. 2018. Journal of neural transmission. 125: 1053-1064 -
Bentsodiatsepiinien pitkäaikaiskäyttö on vähentynyt
Kurko, Terhi; Saastamoinen, Leena; Tuulio-Henriksson, Annamari; Taiminen, Tero; Tiihonen, Jari; Airaksinen, Marja; Hietala, Jarmo. 2018. Lääkärilehti. 73: 1292-1299 -
Burden for Parents of Patients With Schizophrenia - A Nationwide Comparative Study of Parents of Offspring With Rheumatoid Arthritis, Multiple Sclerosis, Epilepsy, and Healthy Controls
Mittendorfer-Rutz, Ellenor; Rahman, Syed; Tanskanen, Anti; Majak, Maila; Mehtälä, Juha; Hoti, Fabian; Jedenius, Erik; Enkusson, Dana; Leval, Amy; Sermon, Jan; Taipale, Hedi; Tiihonen, Jari. 2018. Schizophrenia bulletin. [Published: 03 September 2018]: 1-10 -
Cause-specific mortality in Finnish forensic psychiatric patients
Ojansuu, Ilkka; Putkonen, Hanna; Tiihonen, Jari. 2018. Nordic journal of psychiatry. 72: 374-379 -
Comorbid opioid use is undertreated among forensic patients with schizophrenia
Kivimies, Kristiina; Repo-Tiihonen, Eila; Kautiainen, Hannu; Tiihonen, Jari. 2018. Substance abuse treatment, prevention, and policy. 13: 39 -
Comparison of dispensed medications and forensic-toxicological findings to assess pharmacotherapy in the Swedish population 2006 to 2013
Forsman, J; Taipale, H; Masterman, T; Tiihonen, J; Tanskanen, A. 2018. Pharmacoepidemiology and drug safety. 27: 1112-1122 -
Concomitant use of benzodiazepines and opioids in community-dwelling older people with or without Alzheimer's disease - A nationwide register-based study in Finland
Karttunen, Niina; Taipale, Heidi; Hamina, Aleksi; Tanskanen, Antti; Tiihonen, Jari; Tolppanen, Anna-Maija; Hartikainen, Sirpa. 2018. International journal of geriatric psychiatry. 2019; 34: 280-288 -
Cortical structure abnormalities in females with conduct disorder prior to age 15
Budhiraja, M; Pereira, JB; Lindner, P; Westman, E; Jokinen, J; Savic, I; Tiihonen, J; Hodgins, S. 2018. Psychiatry research: neuroimaging. 2019; 289: 37-44 -
Determinants of hospitalizations for pneumonia among Finnish drug users
Olubamwo, OO; Onyeka, IN; Aregbesola, A; Ronkainen, K; Tiihonen, J; Föhr, J; Kauhanen, J. 2018. SAGE Open Medicine. 6: 1-7 -
Diabetes hospitalizations and deaths in a cohort of treatment-seeking illicit drug users
Aregbesola, Alex; Onyeka, Ifeoma N; Olubamwo, Olubunmi; Ronkainen, Kimmo; Tiihonen, Jari; Föhr, Jaana; Kauhanen, Jussi. 2018. SAGE Open Medicine. 6: 1-5 -
Duration of new antidepressant use and factors associated with discontinuation among community-dwelling persons with Alzheimer's disease
Kettunen, Reetta; Taipale, Heidi; Tolppanen, Anna-Maija; Tanskanen, Antti; Tiihonen, Jari; Hartikainen, Sirpa; Koponen, Marjaana. 2018. European journal of clinical pharmacology. 2019; 75: 417-425 -
Editorial: let's take a break from studying the PPI-fracture association - Authors' reply
Torvinen-Kiiskinen, S; Tolppanen, AM; Koponen, M; Tanskanen, A; Tiihonen, J; Hartikainen, S; Taipale, H. 2018. Alimentary pharmacology and therapeutics. 47: 1544-1545 -
Hospitalization after Oral Antibiotic Initiation in Finnish Community Dwellers with and without Alzheimer's Disease: Retrospective Register-Based Cohort Study
Järvinen, Heli; Taipale, Heidi; Koponen, Marjaana; Tanskanen, Antti; Tiihonen, Jari; Tolppanen, Anna-Maija; Hartikainen, Sirpa. 2018. Journal of Alzheimer's disease. 64: 437-445 -
Impact of opioid initiation on antipsychotic and benzodiazepine and related drug use among persons with Alzheimer's disease
Hamina, Aleksi; Lavikainen, Piia; Tanskanen, Antti; Tolppanen, Anna-Maija; Tiihonen, Jari; Hartikainen, Sirpa; Taipale, Heidi. 2018. International psychogeriatrics. 30: 947-956 -
Incidence and Prevalence of Antiepileptic Medication Use in Community-Dwelling Persons with and without Alzheimer's Disease
Sarycheva, Tatyana; Taipale, Heidi; Lavikainen, Piia; Tiihonen, Jari; Tanskanen, Antti; Hartikainen, Sirpa; Tolppanen, Anna-Maija. 2018. Journal of Alzheimer's disease. 66: 387-395 -
Incident opioid use and risk of hip fracture among persons with Alzheimer's disease, a nationwide matched cohort study
Taipale, Heidi; Hamina, Aleksi; Karttunen, Niina; Koponen, Marjaana; Tanskanen, Antti; Tiihonen, Jari; Hartikainen, Sirpa; Tolppanen, Anna-Maija. 2018. Pain. 2019; 160: 417-423 -
Initiation and long-term use of benzodiazepines and Z-drugs in bipolar disorder
Wingård, Louise; Taipale, Heidi; Reutfors, Johan; Westerlund, Anna; Bodén, Robert; Tiihonen, Jari; Tanskanen, Antti; Andersen, Morten. 2018. Bipolar disorders. 20: 634-646 -
Kuinka pitkään psykoosilääkettä uusille skitsofreniapotilaille?
Tiihonen, Jari; Tanskanen, Antti; Taipale, Heidi. 2018. Duodecim. 134: 1044 -
Mortality in schizophrenia: 30-year nationwide follow-up study
Tanskanen, A; Tiihonen, J; Taipale, H. 2018. Acta psychiatrica scandinavica. 138: 492-499 -
Nurses' Views Highlight a Need for the Systematic Development of Patient Safety Culture in Forensic Psychiatry Nursing
Kuosmanen, Anssi; Tiihonen, Jari; Repo-Tiihonen, Eila; Eronen, Markku; Turunen, Hannele. 2018. Journal of patient safety. [Epub ahead of print 4 Nov 2017]: 1-6 -
Proton pump inhibitor use and risk of hip fractures among community-dwelling persons with Alzheimer's disease - a nested case-control study
Torvinen-Kiiskinen, S; Tolppanen, AM; Koponen, M; Tanskanen, A; Tiihonen, J; Hartikainen, S; Taipale, H. 2018. Alimentary pharmacology and therapeutics. 47: 1135-1142 -
Psychopharmacological treatment, mortality and suicide in bipolar disorder in a Finnish nationwide cohort of 18,018 patients
Lähteenvuo, Markku; Antolín-Concha, Diego; Vattulainen, Pia, Tanskanen, Antti; Taipale, Heidi; Tiihonen, Jari. 2018. Psychiatria Fennica. 49: 10-21 -
Psychotropic drugs use and psychotropic polypharmacy among persons with Alzheimer's disease
Orsel, Kim; Taipale, Heidi; Tolppanen, Anna-Maija; Koponen, Marjaana; Tanskanen, Antti; Tiihonen, Jari; Gardarsdottir, Helga; Hartikainen, Sirpa. 2018. European neuropsychopharmacology. 28: 1260-1269 -
Real-world Effectiveness of Pharmacologic Treatments for the Prevention of Rehospitalization in a Finnish Nationwide Cohort of Patients With Bipolar Disorder
Lähteenvuo, Markku; Tanskanen, Antti; Taipale, Heidi; Hoti, Fabian; Vattulainen, Pia; Vieta, Eduard; Tiihonen, Jari. 2018. JAMA psychiatry. 75: 347-355 -
Response to the editorial on antipsychotics and mortality in a nationwide cohort of 29,823 patients with schizophrenia
Tiihonen, Jari. 2018. Schizophrenia research. 202: 397 -
Risk of Treatment Failure: Response to Czobor and Volavka
Tiihonen, Jari; Tanskanen, Antti; Taipale, Heidi. 2018. American journal of psychiatry. 175: 909 -
Risk of Treatment Failure: Response to Ghosh and Noble
Tiihonen, Jari; Tanskanen, Antti; Taipale, Heidi. 2018. American journal of psychiatry. 175: 1267 -
Systemic Estrogen Use and Discontinuation After Alzheimer's Disease Diagnosis in Finland 2005-2012: A Nationwide Exposure-Matched Cohort Study
Tolppanen, Anna-Maija; Tiihonen, Miia; Taipale, Heidi; Koponen, Marjaana; Tanskanen, Antti; Lavikainen, Piia; Tiihonen, Jari; Hartikainen, Sirpa. 2018. Drugs and aging. 35: 985-992 -
The risk of Alzheimer's disease associated with benzodiazepines and related drugs: a nested case-control study
Tapiainen, V; Taipale, H; Tanskanen, A; Tiihonen, J; Hartikainen, S; Tolppanen, A-M. 2018. Acta psychiatrica scandinavica. 138: 91-100 -
Trends in the long-term use of benzodiazepine anxiolytics and hypnotics: A national register study for 2006 to 2014
Kurko, Terhi; Saastamoinen, Leena K; Tuulio-Henriksson, Annamari; Taiminen, Tero; Tiihonen, Jari; Airaksinen, Marja; Hietala, Jarmo. 2018. Pharmacoepidemiology and drug safety. 27: 674-682 -
Use of antiepileptic drugs and dementia risk - an analysis of Finnish health register and German health insurance data
Taipale, H; Gomm, W; Broich, K; Maier, W; Tolppanen, AM; Tanskanen, A; Tiihonen, J; Hartikainen, S; Haenisch, B. 2018. Journal of the american geriatrics society. 66: 1123-1129 -
Antidepressant use and risk of hip fractures among community-dwelling persons with and without Alzheimer's disease
Torvinen-Kiiskinen Sanna, Tolppanen Anna-Maija, Koponen Marjaana, Tanskanen Antti, Tiihonen Jari, Hartikainen Sirpa, Taipale Heidi. 2017. International journal of geriatric psychiatry. 32: e107-e115 -
Antipsychotic use and the risk of hip fracture among community-dwelling persons with Alzheimer's disease
Koponen M, Taipale H, Lavikainen P, Tanskanen A, Tiihonen J, Tolppanen AM, Ahonen R, Hartikainen S. 2017. Journal of clinical psychiatry. 78: e257-e263 -
Association between route of illicit drug administration and hospitalizations for infective endocarditis
Olubamwo O, Onyeka IN, Aregbesola A, Ronkainen K, Tiihonen J, Föhr J, Kauhanen J. 2017. SAGE Open Medicine. 5: 1-5 -
Brain structure abnormalities in young women who presented conduct disorder in childhood/adolescence
Budhiraja Meenal, Savic Ivanka, Lindner Philip, Jokinen Jussi, Tiihonen Jari, Hodgins Sheilagh. 2017. Cognitive affective and behavioral neuroscience. 17: 869-885 -
Comparative Effectiveness of Antipsychotic Drugs for Rehospitalization in Schizophrenia-A Nationwide Study With 20-Year Follow-up
Taipale Heidi, Mehtälä Juha, Tanskanen Antti, Tiihonen Jari. 2017. Schizophrenia bulletin. Published: 20 December 2017: 1-7 -
De-escalation techniques used, and reasons for seclusion and restraint, in a forensic psychiatric hospital
Kuivalainen S, Vehviläinen-Julkunen K, Louheranta O, Putkonen A, Repo-Tiihonen E, Tiihonen J. 2017. International journal of mental health nursing. 26: 513-524 -
Drug exposure in register-based research - An expert-opinion based evaluation of methods
Tanskanen A, Taipale H, Koponen M, Tolppanen AM, Hartikainen S, Ahonen R, Tiihonen J. 2017. PLoS ONE. 12: e0184070 -
Firesetting and general criminal recidivism among a consecutive sample of Finnish pretrial male firesetters: A register-based follow-up study
Thomson A, Tiihonen J, Miettunen J, Virkkunen M, Lindberg N. 2017. Psychiatry research. 2018; 259: 377-384 -
Genome-wide association studies of a broad spectrum of antisocial behavior
Tielbeek JJ, Johansson A, Polderman TJC, Rautiainen MR, Jansen P, Taylor M, Tong X, Lu Q, Burt AS, Tiemeier H, Viding E, Plomin R, Martin NG, Heath AC, Madden PAF, Montgomery G, Beaver KM, Waldman I, Gelernter J, Kranzler HR et al.. 2017. JAMA psychiatry. 74: 1242-1250 -
Healthcare use among immigrants and natives in Sweden on disability pension, before and after changes of regulations
Di Thiene D, Rahman S, Helgesson M, Wang M, Alexanderson K, Tiihonen J, La Torre G, Mittendorfer-Rutz E. 2017. European journal of public health. [Epub ahead of print 30 Nov 2017]: 1-7 -
Hospital-treated mental and behavioral disorders and risk of Alzheimer's disease: A nationwide nested case-control study
Tapiainen V, Hartikainen S, Taipale H, Tiihonen J, Tolppanen A-M. 2017. European psychiatry. 43: 92-98 -
Huumeiden terveysriskit Suomessa - voiko niitä hallita? HUUTI-tutkimuksen antia
Kauhanen Jussi, Tiihonen Jari. 2017. Duodecim. 133: 34-42 -
Incident Use of a Potentially Inappropriate Medication and Hip Fracture in Community-Dwelling Older Persons With Alzheimer's Disease
Hyttinen V, Taipale H, Tolppanen A-M, Tanskanen A, Tiihonen J, Hartikainen S, Valtonen H. 2017. Annals of pharmacotherapy. 51: 725-734 -
Is Alzheimer's Disease Associated with Previous Opioid Use?
Taipale H, Hamina A, Lampela P, Tanskanen A, Tiihonen J, Karttunen N, Tolppanen AM, Hartikainen S. 2017. Pain medicine. 2018; 19: 2115-2121 -
Long-term use of proton pump inhibitors among community-dwelling persons with and without Alzheimer's disease
Juntunen Heidi, Taipale Heidi, Tanskanen Antti, Tolppanen Anna-Maija, Tiihonen Jari, Hartikainen Sirpa, Tiihonen Miia. 2017. European journal of clinical pharmacology. 73: 1149-1158 -
No Association Between Proton Pump Inhibitor Use and Risk of Alzheimer's Disease
Taipale Heidi, Tolppanen Anna-Maija, Tiihonen Miia, Tanskanen Antti, Tiihonen Jari, Hartikainen Sirpa. 2017. American journal of gastroenterology. 112: 1802-1808 -
Pharmacological treatments and risk of readmission to hospital for unipolar depression in Finland: a nationwide cohort study
Tiihonen Jari, Tanskanen Antti, Hoti Fabian, Vattulainen Pia, Taipale Heidi, Mehtälä Juha, Lähteenvuo Markku. 2017. The Lancet Psychiatry. 4: 547-553 -
Platelet monoamine oxidase activity and interpersonal violence in male suicide attempters
Jokinen Jussi, Königsson Johan, Moberg Tomas, Jönsson Erik G, Tiihonen Jari, Nordström Peter, Oreland Lars, Åsberg Marie. 2017. Psychiatry research. 2018; 260: 173-176 -
Psychopathy and Mortality
Vaurio Olli, Repo-Tiihonen Eila, Kautiainen Hannu, Tiihonen Jari. 2017. Journal of forensic sciences. 2018; 63: 474-477 -
Real-World Effectiveness of Antipsychotic Treatments in a Nationwide Cohort of 29 823 Patients With Schizophrenia
Tiihonen Jari, Mittendorfer-Rutz Ellenor, Majak Maila, Mehtälä Juha, Hoti Fabian, Jedenius Erik, Enkusson Dana, Leval Amy, Sermon Jan, Tanskanen Antti, Taipale Heidi. 2017. JAMA psychiatry. 74: 686-693 -
Reducing the rehospitalization risk after a manic episode: A population based cohort study of lithium, valproate, olanzapine, quetiapine and aripiprazole in monotherapy and combinations
Wingård L, Bodén R, Brandt L, Tiihonen J, Tanskanen A, Kieler H, Andersen M, Reutfors J. 2017. Journal of affective disorders. 217: 16-23 -
Regional changes in psychotropic use among Finnish persons with newly diagnosed Alzheimer's disease in 2005-2011
Tolppanen A-M, Voutilainen A, Taipale H, Tanskanen A, Lavikainen P, Koponen M, Tiihonen J, Hartikainen S. 2017. PLoS ONE. 12: e0173450 -
Risk of Alzheimer's disease among users of postmenopausal hormonetherapy: A nationwide case-control study
Imtiaz B, Taipale H, Tanskanen A, Tiihonen M, Kivipelto M, Heikkinen A-M, Tiihonen J, Soininen H, Hartikainen S, Tolppanen A-M. 2017. Maturitas. 98: 7-13 -
Risk of death associated with new benzodiazepine use among persons with Alzheimer disease: A matched cohort study
Saarelainen Laura, Tolppanen Anna-Maija, Koponen Marjaana, Tanskanen Antti, Tiihonen Jari, Hartikainen Sirpa, Taipale Heidi. 2017. International journal of geriatric psychiatry. 2018; 33: 583-590 -
Risk of disability pension in first and second generation immigrants: the role of age and region of birth in a prospective population-based study from Sweden
Di Thiene D, Helgesson M, Alexanderson K, La Torre G, Tiihonen J, Mittendorfer-Rutz E. 2017. Bmc public health. 17: 931 -
Risk of head and traumatic brain injuries associated with antidepressant use among community-dwelling persons with Alzheimer's disease: a nationwide matched cohort study
Taipale Heidi, Koponen Marjaana, Tanskanen Antti, Lavikainen Piia, Sund Reijo, Tiihonen Jari, Hartikainen Sirpa, Tolppanen Anna-Maija. 2017. Alzheimer's research and therapy. 9: 59 -
Risk of pneumonia associated with incident benzodiazepine use among community-dwelling persons with Alzheimer's disease
Taipale Heidi, Tolppanen Anna-Maija, Koponen Marjaana, Tanskanen Antti, Lavikainen Piia, Sund Reijo, Tiihonen Jari, Hartikainen Sirpa. 2017. Canadian medical association journal. 189: E519-E529 -
Screening approach for identifying candidate drugs and drug-drug interactions related to hip fracture risk in persons with Alzheimer disease
Tolppanen A-M, Taipale H, Koponen M, Tanskanen A, Lavikainen P, Paananen J, Tiihonen J, Hartikainen S. 2017. Pharmacoepidemiology and drug safety. 26: 875-889 -
Seasonal variation of hospital violence, seclusion and restraint in a forensic psychiatric hospital
Kuivalainen Satu, Vehviläinen-Julkunen Katri, Louheranta Olavi, Putkonen Anu, Repo-Tiihonen Eila, Tiihonen Jari. 2017. International journal of law and psychiatry. 52: 1-6 -
The Association of Ambient Temperature and Violent Crime
Tiihonen Jari, Halonen Pirjo, Tiihonen Laura, Kautiainen Hannu, Storvik Markus, Callaway James. 2017. Scientific reports. 7: 6543 -
Trajectories and characteristics of work disability before and after acute myocardial infarction
Wang M, Vaez M, Dorner TE, Tiihonen J, Voss M, Ivert T, Mittendorfer-Rutz E. 2017. Heart. [Epub ahead of print 1 Sept 2017]: 1-9 -
Use of benzodiazepines and related drugs is associated with risk of stroke among persons with Alzheimer's disease
Taipale Heidi, Koponen Marjaana, Tanskanen Antti, Lavikainen Piia, Tolppanen Anna-Maija, Sund Reijo, Tiihonen Jari, Hartikainen Sirpa. 2017. International clinical psychopharmacology. 32: 135-141 -
Use of lithium in patients with unipolar depression - Author's reply
Tiihonen Jari. 2017. The Lancet Psychiatry. 4: 663 -
White matter correlates of psychopathic traits in a female community sample
Lindner P, Budhiraja M, Westerman J, Savic I, Jokinen J, Tiihonen J, Hodgins S. 2017. Social cognitive and affective neuroscience. 12: 1500-1510 -
A Comparison of Sex Differences in Psychotropic Medication Use in Older People with Alzheimer's Disease in the US and Finland
Moga Daniela C, Taipale Heidi, Tolppanen Anna-Maija, Tanskanen Antti, Tiihonen Jari, Hartikainen Sirpa, Wu Qishan, Jicha Gregory A, Gnjidic Danijela. 2016. Drugs and aging. 2017; 34: 55-65 -
Add-on mirtazapine improves orgasmic functioning in patients with schizophrenia treated with first-generation antipsychotics
Terevnikov V, Stenberg JH, Tiihonen J, Burkin M, Joffe G. 2016. Nordic journal of psychiatry. 2017; 71: 77-80 -
Agreement between PRE2DUP register data modeling method and comprehensive drug use interview among older persons
Taipale Heidi, Tanskanen Antti, Koponen Marjaana, Tolppanen Anna-Maija, Tiihonen Jari, Hartikainen Sirpa. 2016. Clinical epidemiology. 8: 363-371 -
Alueelliset erot sairaalapäivissä ja lääkekustannuksissa Alzheimerin tautia sairastavilla ja verrokeilla [English Summary: Regional differences in number of hospital days and drug costs in people with and without Alzheimer's disease]
Taipale Heidi, Tolppanen Anna-Maija, Purhonen Maija, Tanskanen Antti, Ahonen Riitta, Tiihonen Jari, Hartikainen Sirpa. 2016. Lääkärilehti. 71: 1613-1619a -
Anticholinergic Exposure and Risk of Pneumonia in Persons with Alzheimer's Disease: A Nested Case-Control Study
Lampela Pasi, Tolppanen Anna-Maija, Tanskanen Antti, Tiihonen Jari, Hartikainen Sirpa, Taipale Heidi. 2016. Journal of Alzheimer's disease. 2017; 56: 119-128 -
Antipsychotic use and risk of hospitalization or death due to pneumonia in persons with and without Alzheimer's disease
Tolppanen Anna-Maija, Koponen Marjaana, Tanskanen Antti, Lavikainen Piia, Sund Reijo, Tiihonen Jari, Hartikainen Sirpa, Taipale Heidi. 2016. Chest. 150: 1233-1241 -
Association between routes of drug administration and all-cause mortality among drug users
Onyeka Ifeoma N, Basnet Sushil, Beynon Caryl M, Tiihonen Jari, Föhr Jaana, Kauhanen Jussi. 2016. Journal of substance use. 21: 559-565 -
Cognitive insight, clinical insight, and reasoning in schizophrenia: a pilot study in a forensic setting
Kuokkanen R, Lappalainen R, Repo-Tiihonen E, Tiihonen J, Aho-Mustonen K. 2016. Journal of forensic psychology practice. 16: 253-267 -
Cohort profile: the Finnish Medication and Alzheimer's disease (MEDALZ) study
Tolppanen Anna-Maija, Taipale Heidi, Koponen Marjaana, Lavikainen Piia, Tanskanen Antti, Tiihonen Jari, Hartikainen Sirpa. 2016. BMJ open. 6: e012100 -
Comparison of predictors of hip fracture and mortality after hip fracture in community-dwellers with and without Alzheimer's disease - exposure-matched cohort study
Tolppanen Anna-Maija, Taipale Heidi, Tanskanen Antti, Tiihonen Jari, Hartikainen Sirpa. 2016. Bmc geriatrics. 16: 204 -
Conduct disorder in females is associated with reduced corpus callosum structural integrity independent of comorbid disorders and exposure to maltreatment
Lindner P, Savic I, Sitnikov R, Budhiraja M, Liu Y, Jokinen J, Tiihonen J, Hodgins S. 2016. Translational psychiatry. 6: e714 -
Dementialääkkeitä käytetään esitettyä pidempään [Ajassa
Hartikainen Sirpa, Paananen Jussi, Taipale Heidi, Tanskanen Antti, Tiihonen Jari, Tolppanen Anna-Maija. 2016. Lääkärilehti. 71: 3003 -
Differences in analgesic use in community-dwelling persons with and without Alzheimer's disease
Hamina Aleksi, Taipale Heidi, Tanskanen Antti, Tolppanen Anna-Maija, Tiihonen Jari, Hartikainen Sirpa. 2016. European journal of pain. 2017; 21: 658-667 -
Drug use in persons with and without Alzheimer's disease aged 90 years or more
Taipale Heidi, Koponen Marjaana, Tanskanen Antti, Tolppanen Anna-Maija, Tiihonen Jari, Hartikainen Sirpa. 2016. Age and ageing. 45: 900-904 -
Effects of Scheduled Waiting for Psychotherapy in Patients With Major Depression
Ahola P, Joensuu M, Knekt P, Lindfors O, Saarinen P, Tolmunen T, Valkonen-Korhonen M, Jääskeläinen T, Virtala E, Tiihonen J, Lehtonen J. 2016. Journal of nervous and mental disease. 205: 611-617 -
Fire-setting performed in adolescence or early adulthood predicts schizophrenia: a register-based follow-up study of pre-trial offenders
Thomson A, Tiihonen J, Miettunen J, Virkkunen M, Lindberg N. 2016. Nordic journal of psychiatry. 2017; 71: 96-101 -
Genome-wide association study of antisocial personality disorder
Rautiainen M-R, Paunio T, Repo-Tiihonen E, Virkkunen M, Ollila HM, Sulkava S, Jolanki O, Palotie A, Tiihonen J. 2016. Translational psychiatry. 6: e883 -
Incidence and Duration of Cumulative Bisphosphonate Use among Community-Dwelling Persons with or without Alzheimer's Disease
Tiihonen Miia, Taipale Heidi, Tanskanen Antti, Tiihonen Jari, Hartikainen Sirpa. 2016. Journal of Alzheimer's disease. 52: 127-132 -
Incidence of antidepressant use in community-dwelling persons with and without Alzheimer's disease: 13-year follow-up
Puranen Arto, Taipale Heidi, Koponen Marjaana, Tanskanen Antti, Tolppanen Anna-Maija, Tiihonen Jari, Hartikainen Sirpa. 2016. International journal of geriatric psychiatry. 2017; 32: 94-101 -
Increased steroid hormone dehydroepiandrosterone and pregnenolone levels in post-mortem brain samples of alcoholics
Kärkkäinen Olli, Häkkinen Merja R, Auriola Seppo, Kautiainen Hannu, Tiihonen Jari, Storvik Markus. 2016. Alcohol. 52: 63-70 -
Influence of a HTR2B stop codon on glucagon homeostasis and glucose excursion in non-diabetic men
Tikkanen R, Saukkonen T, Fex M, Bennet H, Rautiainen MR, Paunio T, Koskinen M, Panarsky R, Bevilacqua L, Sjöberg RL, Tiihonen J, Virkkunen M. 2016. Experimental and clinical endocrinology and diabetes. 124: 529-534 -
Long-term use of opioids for non-malignant pain among community-dwelling persons with and without Alzheimer disease in Finland: a nationwide register-based study
Hamina Aleksi, Taipale Heidi, Tanskanen Antti, Tolppanen Anna-Maija, Karttunen Niina, Pylkkänen Liisa, Tiihonen Jari, Hartikainen Sirpa. 2016. Pain. 2017; 158: 252-260 -
Month and Season of Birth as a Risk Factor for Alzheimer's Disease: A Nationwide Nested Case-control Study
Tolppanen Anna-Maija, Ahonen Riitta, Koponen Marjaana, Lavikainen Piia, Purhonen Maija, Taipale Heidi, Tanskanen Antti, Tiihonen Jari, Tiihonen Miia, Hartikainen Sirpa. 2016. Journal of preventive medicine and public health. 49: 134-138 -
Mortality and cumulative exposure to antipsychotics, antidepressants, and benzodiazepines in patients with schizophrenia: an observational follow-up study
Tiihonen J, Mittendorfer-Rutz E, Torniainen M, Alexanderson K, Tanskanen A. 2016. American journal of psychiatry. 173: 600-6 -
Nurses' Time Use in Forensic Psychiatry: Core Interventions Outlined in the Finnish Clinical Practice Guideline on Schizophrenia
Tenkanen Helena, Taskinen Helena, Kontio Raija, Repo-Tiihonen Eila, Tiihonen Jari, Kinnunen Juha. 2016. Journal of forensic nursing. 12: 64-73 -
Psykoosilääkkeet yhteydessä Alzheimer-potilaiden keuhkokuumeriskiin
Tolppanen Anna-Maija, Koponen Marjaana, Tanskanen Antti, Lavikainen Piia, Sund Reijo, Tiihonen Jari, Hartikainen Sirpa, Taipale Heidi. 2016. Duodecim. 132: 1490 -
Real-world effectiveness of antipsychotics
Tiihonen Jari. 2016. Acta psychiatrica scandinavica. 134: 371-373 -
Risk Factors for Initiation of Potentially Inappropriate Medications in Community-Dwelling Older Adults with and without Alzheimer's Disease
Hyttinen Virva, Taipale Heidi, Tanskanen Antti, Tiihonen Jari, Tolppanen Anna-Maija, Hartikainen Sirpa, Valtonen Hannu. 2016. Drugs and aging. 2017; 34: 67-77 -
Risk of Hip Fracture in Benzodiazepine Users With and Without Alzheimer Disease
Saarelainen Laura, Tolppanen Anna-Maija, Koponen Marjaana, Tanskanen Antti, Sund Reijo, Tiihonen Jari, Hartikainen Sirpa, Taipale Heidi. 2016. Journal of the american medical directors association. 2017; 18: 87.e15-87.e21 -
Risk of Mortality associated with Antipsychotic Monotherapy and Polypharmacy among Community-Dwelling Persons with Alzheimer's Disease
Koponen Marjaana, Taipale Heidi, Lavikainen Piia, Tanskanen Antti, Tiihonen Jari, Tolppanen Anna-Maija, Ahonen Riitta, Hartikainen Sirpa. 2016. Journal of Alzheimer's disease. 2017; 56: 107-118 -
The effects of a HTR2B stop codon and testosterone on energy metabolism and beta cell function among antisocial Finnish males
Tikkanen R, Saukkonen T, Fex M, Bennet H, Rautiainen MR, Paunio T, Koskinen M, Panarsky R, Bevilacqua L, Sjöberg RL, Tiihonen J, Virkkunen M. 2016. Journal of psychiatric research. Jun 25;81: 79-86 -
Use of antidementia drugs and risk of pneumonia in older persons with Alzheimer's disease
Lampela Pasi, Tolppanen Anna-Maija, Tanskanen Antti, Tiihonen Jari, Lavikainen Piia, Hartikainen Sirpa, Taipale Heidi. 2016. Annals of medicine. 2017; 49: 230-239 -
A pilot study of group administered metacognitive training (MCT) for schizophrenia patients in a high-security forensic setting: subjective training success and health-related quality of life
Kuokkanen Riitta, Aho-Mustonen Kati, Muotka Joona, Lappalainen Raimo, Tiihonen Jari. 2015. Journal of forensic psychology practice. 15: 344-362 -
Antipsychotic Treatment and Mortality in Schizophrenia
Torniainen Minna, Mittendorfer-Rutz Ellenor, Tanskanen Antti, Bjorkenstam Charlotte, Suvisaari Jaana, Alexanderson Kristina, Tiihonen Jari. 2015. Schizophrenia bulletin. 41: 656-663 -
Baseline symptom severity predicts serotonin transporter change during psychotherapy in patients with major depression
Joensuu M, Ahola P, Knekt P, Lindfors O, Saarinen P, Tolmunen T, Valkonen-Korhonen M, Vanninen R, Jääskeläinen T, Virtala E, Kuikka J, Tiihonen J, Lehtonen J. 2015. Psychiatry and clinical neurosciences. 2016; 70: 34-41 -
Characteristics of drug-abusing females with and without children seeking treatment in Helsinki, Finland
Basnet Sushil, Onyeka Ifeoma N, Tiihonen Jari, Föhr Jaana, Kauhanen Jussi. 2015. Scandinavian journal of public health. 43: 221-228 -
Decreased [³H]naloxone Binding in the Dentate Gyrus of Cloninger Type 1 Anxiety-Prone Alcoholics: A Postmortem Whole-Hemisphere Autoradiography Study
Laukkanen Virpi, Kärkkäinen Olli, Kautiainen Hannu, Tiihonen Jari, Storvik Markus. 2015. Alcoholism-clinical and experimental research. 39: 1352-1359 -
Factors associated with hospitalization for blood-borne viral infections among treatment-seeking illicit drug users
Onyeka Ifeoma N, Olubamwo Olubunmi, Beynon Caryl M, Ronkainen Kimmo, Föhr Jaana, Tiihonen Jari, Tuomola Pekka, Tasa Niko, Kauhanen Jussi. 2015. Journal of substance abuse treatment. 53: 71-77 -
From prescription drug purchases to drug use periods - a second generation method (PRE2DUP)
Tanskanen Antti, Taipale Heidi, Koponen Marjaana, Tolppanen Anna-Maija, Hartikainen Sirpa, Ahonen Riitta, Tiihonen Jari. 2015. Bmc medical informatics and decision making. 15: 21 -
Hospital care and drug costs from five years before until two years after the diagnosis of Alzheimer's disease in a Finnish nationwide cohort
Taipale Heidi, Purhonen Maija, Tolppanen Anna-Maija, Tanskanen Antti, Tiihonen Jari, Hartikainen Sirpa. 2015. Scandinavian journal of public health. 44(2016): 150-158 -
Hospital-treated suicide attempts among Finnish fire setters: A follow-up study
Thomson Annika, Tiihonen Jari, Miettunen Jouko, Virkkunen Matti, Lindberg Nina. 2015. Criminal behaviour and mental health. [epub ahead of print 17 AUG 2015]: - -
Hospitalization in a Cohort Seeking Treatment for Illicit Drug Use in Finland
Onyeka Ifeoma N, Beynon Caryl M, Ronkainen Kimmo, Tiihonen Jari, Föhr Jaana, Kuikanmäki Outi, Paasolainen Mika, Kauhanen Jussi. 2015. Journal of substance abuse treatment. 53: 64-70 -
Impulsive alcohol-related risk-behavior and emotional dysregulation among individuals with a serotonin 2B receptor stop codon
Tikkanen R, Tiihonen J, Rautiainen MR, Paunio T, Bevilacqua L, Panarsky R, Goldman D, Virkkunen M. 2015. Translational psychiatry. 5: e681 -
Incidence of antipsychotic use in relation to diagnosis of Alzheimer's disease among community-dwelling persons
Koponen Marjaana, Tolppanen Anna-Maija, Taipale Heidi, Tanskanen Antti, Tiihonen Jari, Johnell Kristina, Fastbom Johan, Ahonen Riitta, Hartikainen Sirpa. 2015. British journal of psychiatry. 207: 444-449 -
Lithium is associated with decrease in all-cause and suicide mortality in high-risk bipolar patients: a nationwide registry-based prospective cohort study
Toffol Elena, Hätönen Taina, Tanskanen Antti, Lönnqvist Jouko, Wahlbeck Kristian, Joffe Grigori, Tiihonen Jari, Haukka Jari, Partonen Timo. 2015. Journal of affective disorders. 183: 159-165 -
Long-term use of antipsychotics among community-dwelling persons with Alzheimer's disease: A nationwide register-based study
Koponen Marjaana, Taipale Heidi, Tanskanen Antti, Tolppanen Anna-Maija, Tiihonen Jari, Ahonen Riitta, Hartikainen Sirpa. 2015. European neuropsychopharmacology. 25: 1706-1713 -
Long-term use of benzodiazepines and related drugs among community-dwelling individuals with and without Alzheimer's disease
Taipale Heidi, Koponen Marjaana, Tanskanen Antti, Tolppanen Anna-Maija, Tiihonen Jari, Hartikainen Sirpa. 2015. International clinical psychopharmacology. 30: 202-208 -
Long-term use of benzodiazepines: Definitions, prevalence and usage patterns - a systematic review of register-based studies
Kurko TAT, Saastamoinen LK, Tähkäpää T, Tuulio-Henriksson A, Taiminen T, Tiihonen J, Airaksinien MS, Hietala J. 2015. European psychiatry. 30: 1037-1047 -
Mortality among forensic psychiatric patients in Finland
Ojansuu Ilkka, Putkonen Hanna, Tiihonen Jari. 2015. Nordic journal of psychiatry. 69: 25-27 -
Opioid abuse and hospitalization rates in patients with schizophrenia
Kivimies Kristiina, Repo-Tiihonen Eila, Kautiainen Hannu, Maaranen Päivi, Muhonen Leea H., Heikkinen Martti , Tiihonen Jari. 2015. Nordic journal of psychiatry. 2016; 70: 128-132 -
Potential Years of Life Lost Due to Premature Mortality Among Treatment-Seeking Illicit Drug Users in Finland
Onyeka Ifeoma N, Beynon Caryl M, Vohlonen Ilkka, Tiihonen Jari, Föhr Jaana, Ronkainen Kimmo, Kauhanen Jussi. 2015. Journal of community health. 40: 1099-1106 -
Predictors for initiation of pharmacological prophylaxis in patients with newly diagnosed bipolar disorder - A nationwide cohort study
Scheen Louise, Brandt Lena, Boden Robert, Tiihonen Jari, Andersen Morten, Kieler Helle, Reutfors Johan. 2015. Journal of affective disorders. 172: 204-210 -
Prevalence of Drug Combinations Increasing Bleeding Risk Among Warfarin Users With and Without Alzheimer's Disease
Taipale Heidi, Vuorikari Hanna, Tanskanen Antti, Koponen Marjaana, Tiihonen Jari, Kettunen Raimo, Hartikainen Sirpa. 2015. Drugs and aging. 32: 937-945 -
Psychopathic traits among a consecutive sample of Finnish pretrial fire-setting offenders
Thomson Annika, Tiihonen Jari, Miettunen Jouko, Sailas Eila, Virkkunen Matti, Lindberg Nina. 2015. Bmc psychiatry. 15: 44 -
Psychotropic drugs and homicide: A prospective cohort study from Finland
Tiihonen Jari, Lehti Martti, Aaltonen Mikko, Kivivuori Janne, Kautiainen Hannu, Virta Lauri J., Hoti Fabian, Tanskanen Antti, Korhonen Pasi. 2015. World psychiatry. 14: 245-247 -
The Incidence of Benzodiazepine and Related Drug Use in Persons with and without Alzheimer's Disease
Saarelainen Laura, Taipale Heidi, Koponen Marjaana, Tanskanen Antti, Tolppanen Anna-Maija, Tiihonen Jari, Hartikainen Sirpa. 2015. Journal of Alzheimer's disease. 2016; 49: 809-818 -
Aivosairaudet ovat kalleimmat kansantautimme
Lindsberg Perttu J, Castrén Eero, Korkeila Jyrki, Alho Hannu, Erkinjuntti Timo, Isometsä Erkki, Kalso Eija, Marttunen Mauri, Pihko Helena, Tienari Pentti, Wartiovaara Anu, Jäkälä Pekka, Kälviäinen Reetta, Soininen Hilkka, Tiihonen Jari, Karlsson Hasse, Rinne Juha, Roine Risto O, Elovaara Irina, Tamminen Tuula, Öhman Juha, Majamaa Kari, Hari Riitta. 2014. Duodecim. 130: 1721-1730 -
Antidementia drug use among community-dwelling individuals with Alzheimer's disease in Finland: a nationwide register-based study
Taipale Heidi, Tanskanen Antti, Koponen Marjaana, Tolppanen Anna-Maija, Tiihonen Jari, Hartikainen Sirpa. 2014. International clinical psychopharmacology. 29: 216-223 -
Antipsychotic Doses Among Community-Dwelling Persons With Alzheimer Disease in Finland
Taipale Heidi, Koponen Marjaana, Tanskanen Antti, Tolppanen Anna-Maija, Tiihonen Jari, Hartikainen Sirpa. 2014. Journal of clinical psychopharmacology. 34: 435-440 -
Antipsychotic Polypharmacy among a Nationwide Sample of Community-Dwelling Persons with Alzheimer's Disease
Taipale Heidi, Koponen Marjaana, Tanskanen Antti, Tolppanen Anna-Maija, Tiihonen Jari, Hartikainen Sirpa. 2014. Journal of Alzheimer's disease. 41: 1223-1228 -
Association of socio-demographic factors, sick-leave and health care patterns with the risk of being granted a disability pension among psychiatric outpatients with depression
Mittendorfer-Rutz E, Härkänen T, Tiihonen J, Haukka J. 2014. PLoS ONE. 9: e99869 -
Basal insulin secretion, PCL-R and recidivism among impulsive violent alcoholic offenders
Ojala Kari PT, Tiihonen Jari, Repo-Tiihonen Eila, Tikkanen Roope, Virkkunen Matti. 2014. Psychiatry research. 225: 420-424 -
Concomitant Use of Acetylcholine Esterase Inhibitors and Urinary Antispasmodics Among Finnish Community-Dwelling Persons With Alzheimer Disease
Torvinen-Kiiskinen Sanna, Taipale Heidi, Tanskanen Antti, Tiihonen Jari, Hartikainen Sirpa. 2014. Journal of clinical psychopharmacology. 34: 722-727 -
Factors associated with buprenorphine compared to amphetamine abuse among clients seeking treatment in Finland
Uosukainen Hanna, Ilomäki Jenni, Kauhanen Jussi, Tacke Ulrich, Föhr Jaana, Tiihonen Jari, Bell J. Simon. 2014. Journal of substance abuse treatment. 46: 561-566 -
From prescriptions to drug use periods - things to notice
Tanskanen Antti, Taipale Heidi, Koponen Marjaana, Tolppanen Anna-Maija, Hartikainen Sirpa, Ahonen Riitta, Tiihonen Jari. 2014. Bmc research notes. 7: 796 -
Genetic background of extreme violent behavior
Tiihonen J, Rautiainen M-R, Ollila HM, Repo-Tiihonen E, Virkkunen M, Palotie A, Pietiläinen O, Kristiansson K, Joukamaa M, Lauerma H, Saarela J, Tyni S, Vartiainen H, Paananen J, Goldman D, Paunio T. 2014. Molecular psychiatry. 2015; 20: 786-792 -
High prevalence of psychotropic drug use among persons with and without Alzheimer's disease in Finnish nationwide cohort
Taipale Heidi, Koponen Marjaana, Tanskanen Antti, Tolppanen Anna-Maija, Tiihonen Jari, Hartikainen Sirpa. 2014. European neuropsychopharmacology. 24: 1729-1737 -
Increased metabotropic glutamate 2/3 receptor binding in the perigenual anterior cingulate cortex of Cloninger type 2 alcoholics: a whole-hemisphere autoradiography study
Laukkanen Virpi, Kärkkäinen Olli, Kupila Jukka, Kautiainen Hannu, Tiihonen Jari, Storvik Markus. 2014. Alcohol and alcoholism. 50 (2015): 62-67 -
Kun psyykenlääke vain katoaa
Purhonen Maija, Koponen Hannu, Tiihonen Jari, Tanskanen Antti. 2014. Duodecim. 130: 438-439 -
Lower [3H]Citalopram Binding in Brain Areas Related to Social Cognition in Alcoholics
Kärkkäinen Olli, Laukkanen Virpi, Haukijärvi Tuija, Kautiainen Hannu, Tiihonen Jari, Storvik Markus. 2014. Alcohol and alcoholism. 2015; 50: 46-50 -
Metacognitive group training for forensic and dangerous non-forensic patients with schizophrenia: A randomised controlled feasibility trial
Kuokkanen Riitta, Lappalainen Raimo, Repo-Tiihonen Eila, Tiihonen Jari. 2014. Criminal behaviour and mental health. 24: 345-357 -
Mortality of firesetters: A follow-up study of Finnish male firesetters who underwent a pretrial forensic examination in 1973-1998
Thomson Annika, Tiihonen Jari, Miettunen Jouko, Virkkunen Matti, Lindberg Nina. 2014. Psychiatry research. 225: 638-642 -
Oikeuspsykiatria
Tiihonen Jari. Teoksessa: Lönnqvist Jouko, Henriksson Markus, Marttunen Mauri, Partonen Timo(toim.) , 2014. Psykiatria. s. 697-715. -
Patterns and 14-year trends in mortality among illicit drug users in Finland: The HUUTI study
Onyeka Ifeoma N, Beynon Caryl M, Hannila Marja-Leena, Tiihonen Jari, Föhr Jaana, Tuomola Pekka, Kuikanmäki Outi, Tasa Niko, Paasolainen Mika, Kauhanen Jussi. 2014. International journal of drug policy. 25: 1047-1053 -
Previous forensic mental examination is a useful marker indicating effective violence relapse prevention among psychotic patients
Kivimies Kristiina, Repo-Tiihonen Eila, Kautiainen Hannu, Tiihonen Jari. 2014. Nordic journal of psychiatry. 68: 311-315 -
Skitsofrenian käypä hoito -suosituksen toteuttaminen Niuvanniemen sairaalassa
Tuppurainen Heli, Kivistö Päivi, Repo-Tiihonen Eila, Tiihonen Jari. 2014. Lääkärilehti. 69: 2549-2553 -
The C90RF72 expansion does not affect the phenotype in Nasu-Hakola disease with the DAP12 mutation
Solje Eino, Hartikainen Päivi, Valori Miko, Vanninen Ritva, Tiihonen Jari, Hakola Panu, Tienari Pentti J, Remes Anne M. 2014. Neurobiology of aging. 35: 1780.e13-1780.e17 -
[3H]Ifenprodil binding in post-mortem brains of Cloninger type 1 and 2 alcoholics: A whole-hemisphere autoradiography study
Kupila Jukka, Kärkkäinen Olli, Laukkanen Virpi, Häkkinen Merja, Kautiainen Hannu, Tiihonen Jari, Storvik Markus. 2014. Psychiatry research: neuroimaging. 2015; 231: 197-201 -
AMPA receptors in post-mortem brains of Cloninger type 1 and 2 alcoholics: A whole-hemisphere autoradiography study
Kärkkäinen Olli, Kupila Jukka, Häkkinen Merja, Laukkanen Virpi, Tupala Erkki, Kautiainen Hannu, Tiihonen Jari, Storvik Markus. 2013. Psychiatry research: neuroimaging. 214: 429-434 -
Atypical nucleus accumbens morphology in psychopathy: Another limbic piece in the puzzle
Boccardi M, Bocchetta M, Aronen HJ, Repo-Tiihonen E, Vaurio O, Thompson PM, Tiihonen J, Frisoni GB. 2013. International journal of law and psychiatry. 36: 157-167 -
Cavum septum pellucidum and psychopathy
Toivonen P, Könönen M, Niskanen E, Vaurio O, Repo-Tiihonen E, Seppänen A, Aronen HJ, Vanninen R, Tiihonen J, Laakso MP. 2013. British journal of psychiatry. 203: 152-153 -
Cluster-randomized controlled trial of reducing seclusion and restraint in secured care of men with schizophrenia
Putkonen A, Kuivalainen S, Louheranta O, Repo-Tiihonen E, Ryynänen O-P, Kautiainen H, Tiihonen J. 2013. Psychiatric services. 64: 850-855 -
Coexisting social conditions and health problems among clients seeking treatment for illicit drug use in Finland: The HUUTI study
Onyeka Ifeoma N, Beynon Caryl M, Uosukainen Hanna, Korhonen Maarit J, Ilomäki Jenni, Bell J. Simon, Paasolainen Mika, Tasa Niko, Tiihonen Jari, Kauhanen Jussi. 2013. Bmc public health. 13: 380 -
Decreased GABA(A) benzodiazepine binding site densities in postmortem brains of Cloninger type 1 and 2 alcoholics
Laukkanen Virpi, Storvik Markus, Häkkinen Merja, Akamine Yumiko, Tupala Erkki, Virkkunen Matti, Tiihonen Jari. 2013. Alcohol. 47: 103-108 -
Description of long-term polypharmacy among schizophrenia outpatients
Suokas JT, Suvisaari JM, Haukka J, Korhonen P, Tiihonen J. 2013. Social psychiatry and psychiatric epidemiology. 48: 631-638 -
Endogenous cannabinoids in amygdala and hippocampus in post-mortem brains of Cloninger type 1 and 2 alcoholics
Kärkkäinen Olli K, Lehtonen Marko, Laukkanen Virpi, Tupala Erkki, Hyytiä Petri, Kautiainen Hannu, Tiihonen Jari, Callaway JC, Storvik Markus. 2013. Alcohol. 47: 399-403 -
Exome sequence analysis of Finnish patients with clozapine-induced agranulocytosis
Tiwari AK, Need AC, Lohoff FW, Zai CC, Chowdhury NI, Müller DJ, Putkonen A, Repo-Tiihonen E, Hallikainen T, Anil Yağcıoğlu AE, Tiihonen J, Kennedy JL, Meltzer HY. 2013. Molecular psychiatry. e-pub: e-pub -
Extended-release methylphenidate for treatment of amphetamine/metamphetamine depence: a randomized, double-blind, placebo-controlled trial
Miles SW, Sheridan J, Russell B, Kydd R, Wheeler A, Walters C, Gamble G, Hardley P, Jensen M, Kuoppasalmi K, Tuomola P, Föhr J, Kuikanmäki O, Vorma H, Salokangas R, Mikkonen A, Kallio M, Kauhanen J, Kiviniemi V, Tiihonen J. 2013. Addiction. 108: 1279-86 -
Influence of serotonin transporter gene polymorphism (5-HTTLPR polymorphism) on the relation between brain 5-HT transporter binding and heart rate corrected cardiac repolarization interval
Kauppila E, Vanninen E, Kaurijoki S, Karhunen L, Pietiläinen KH, Rissanen A, Tiihonen J, Pesonen U, Kaprio J. 2013. PLoS ONE. 8: e50303 -
Letter to the Editor (Clozapine resistance - Augmentation strategies)
Tiihonen J, Leucht S. 2013. European neuropsychopharmacology. 23: 338 -
Mortality among clients seeking treatment for buprenorphine abuse in Finland. Erratum in Drug Alcohol Depend 2014: 142:361
Uosukainen Hanna, Kauhanen Jussi, Bell J. Simon, Ronkainen Kimmo, Tiihonen Jari, Föhr Jaana, Onyeka Ifeoma N, Korhonen Maarit J. 2013. Drug and alcohol dependence. 133: 391-397 -
Patient Safety Culture in Two Finnish State-Run Forensic Psychiatric Hospitals
Kuosmanen Anssi, Tiihonen Jari, Repo-Tiihonen Eila, Eronen Markku, Turunen Hannele. 2013. Journal of forensic nursing. Epub: 1-10 -
Predictors and mediators of add-on mirtazapine-induced cognitive enhancement in schizophrenia - A path model investigation
Stenberg J-H, Terevnikov V, Joffe M, Tiihonen J, Chukhin E, Burkin M, Joffe G. 2013. Neuropharmacology. 64: 248-253 -
Relationships between pharmacotherapy-induced metabolic changes and improved psychopathology in schizophrenia: data from a mirtazapine and first-generation antipsychotics combination trial
Terevnikov V, Stenberg J-H, Tiihonen J, Chukhin E, Joffe M, Burkin M, Joffe G. 2013. International journal of neuropsychopharmacology. 16: 1661-1666 -
Use of existing data sources in clinical epidemiology: Finnish health care registers in Alzheimer's disease research - the Medication use among persons with Alzheimer's disease (MEDALZ-2005) study
Tolppanen Anna-Maija, Taipale Heidi, Koponen Marjaana, Lavikainen Piia, Tanskanen Antti, Tiihonen Jari, Hartikainen Sirpa. 2013. Clinical epidemiology. 5: 277-285 -
Using the HCR-20 to predict aggressive behavior among men with schizophrenia living in the community: accuracy of prediction, general and forensic settings, and dynamic risk factors
Michel SF, Riaz M, Webster C, Hart SD, Levander S, Müller-Isberner R, Tiihonen J, Repo-Tiihonen E, Tuninger E, Hodgins S. 2013. International journal of forensic mental health. 12: 1-13 -
Violent behaviour in a forensic psychiatric hospital in Finland: an analysis of violence incident reports
Kuivalainen S, Vehviläinen-Julkunen K, Putkonen A, Louheranta O, Tiihonen J.. 2013. Journal of psychiatric and mental health nursing. : 1-5 -
Voisiko luonnon oma säilöntäaine mullistaa psykoosin hoidon?
Tiihonen J. 2013. Duodecim. 129: 2098-2099 -
Word list learning in patients with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy
Vanhanen M, Hakola P, Ilonen T, Tiihonen J. 2013. Dementia and geriatric cognitive disorders. 3: 10-15 -
Antipsychotic polypharmacy in clozapine resistant schizophrenia: a randomized controlled trial of tapering antipsychotic co-treatment
Repo-Tiihonen E, Hallikainen T, Kivistö P, Tiihonen J. 2012. Mental illness. 4: e1 -
Cardiovascular morbidity, mortality, and pharmacotherapy in patients with schizophrenia.
Lahti M, Tiihonen J, Wildgust H, Beary M, Hodgson R, Kajantie E, Osmond C, Räikkönen K, Eriksson JG. 2012. Psychological medicine. 42: 2275-2285 -
Examining the effectiveness of antipsychotic medication in first-episode psychosis
Taylor M, Cavanagh J, Hodgson R, Tiihonen J.. 2012. Journal of psychopharmacology. 26: 27-32 -
Exome sequencing followed by large-scale genotyping suggests a limited role for moderately rate risk factors of strong effect in schizophrenia
Need AC, McEvoy JP, Gennarelli M, Heinzen EL, Ge D, Maia JM, Shianna KV, He M, Cirulli ET, Gumbs CE, Zhao Q, Campbell CR, Hong L, Rosenquist P, Putkonen A, Hallikainen T, Repo-Tiihonen E, Tiihonen J, Levy DL, Meltzer HY, Goldstein DB. 2012. American journal of human genetics. 91: 303-312 -
Nalreksoni-implantti hyödyttää moniriippuvaisia huumeiden käyttäjiä
Tiihonen J, Krupitsky E, Verbitskaya E, Blokhina E, Mamontova O, Föhr J, Tuomola P, Kuoppasalmi K, Kiviniemi V, Zwartau E. 2012. Duodecim. 128: 830 -
Naltrexone implant for the treatment of polydrug dependence: a randomized controlled trial.
Tiihonen J, Krupitsky E, Verbitskaya E, Blokhina E, Mamontova O, Föhr J, Tuomola P, Kuoppasalmi K, Kiviniemi V, Zwartau E.. 2012. American journal of psychiatry. 169: 531-536 -
Outcome of patients after market withdrawal of thioridazine. A retrospective analysis in a nationwide cohort
Purhonen M, Koponen H, Tiihonen J, Tanskanen A. 2012. Pharmacoepidemiology and drug safety. 21: 1227-1231 -
Polypharmacy with antipsychotics, antidepressants, or benzodiazepines and mortality in schizophrenia
Tiihonen J, Suokas JT, Suvisaari JM, Haukka J, Korhonen P. 2012. Archives of general psychiatry. 69: 476-483 -
Potilasturvallisuuskulttuurin arviointi -kysely valtion oikeuspsykiatristen sairaaloiden henkilöstölle
Kuosmanen Anssi, Tiihonen Jari, Repo-Tiihonen Eila, Eronen Markku, Turunen Hannele. Teoksessa: Kääriäinen Maria, Elo Satu, Kaakinen Pirjo, Helvi Kyngäs(toim.) , 2012. Alakko nää mua? Yhteistyöllä vaikuttavaa hoitotieteellistä tutkimusta, XII Kansallinen hoitotieteellinen konferenssi 27.-28.9.2012, Oulun yliopisto, Proceedings. s. 49-53. -
Reply to Drs. Nauta and van Domburg
Haukka J, Niskanen L, Partonen T, Lönnqvist J, Tiihonen J. 2012. Pharmacoepidemiology and drug safety. 21: 342 -
Rorschach assessment of personality functioning in patients with polycystic lipomembraneous osteodysplasia with sclerosing leukoencephalopathy
Ilonen T, Hakola HPA, Vanhanen M, Tiihonen J. 2012. Acta neuropsychiatrica. 24: 236-244 -
Sociodemographic characteristics and drug abuse patterns of treatment-seeking illicit drug abusers in Finland 1997-2008: The HUUTI study
Onyeka Ifeoma N, Uosukainen Hanna, Korhonen Maarit J, Beynon Caryl, Bell J Simon, Ronkainen Kimmo, Föhr Jaana, Tiihonen Jari, Kauhanen Jussi. 2012. Journal of addictive diseases. 31: 350-362 -
Statin usage and all-cause and disease-specific mortality in a nationwide study
Haukka J, Niskanen L, Partonen T, Lönnqvist J, Tiihonen J.. 2012. Pharmacoepidemiology and drug safety. 21: 61-69 -
The net effect of smoking on healthcare and welfare costs. A cohort study.
Tiihonen J, Ronkainen K, Kangasharju A, Kauhanen J. 2012. BMJ open. 2: e001678 -
The substance use of among forensic psychiatric patients
Kivimies K, Repo-Tiihonen E, Tiihonen J. 2012. American journal of drug and alcohol abuse. 38: 273-277 -
Toward molecular psychotherapy of depression?
Lehtonen J, Tiihonen J, Joensuu MMO, Lehto SM, Ahola PA, Saarinen PI, Valkonen-Korhonen M, Tolmunen T, Kuikka JT. Teoksessa: Levy RA, Ablon JS, Kächele H,(toim.) , 2012. Psychodynamic psychotherapy research: Evidence-based practice and practice-based evidence. s. 219-232. Humana Press -
Twelve-year trend in treatment seeking for buprenorphine abuse in Finland
Uosukainen Hanna, Kauhanen Jussi, Voutilainen Sari, Föhr Jaana, Paasolainen Mika, Tiihonen Jari, Laitinen Kirsti, Onyeka Ifeoma N, Bell J Simon. 2012. Drug and alcohol dependence. 2013:127: 207-214 -
Use of benzodiazepines in adults with schizophrenia is associated with increased mortality
Tiihonen J, Suokas JT, Suvisaari JM. 2012. Evidence-based mental health. 15: 97 -
Whole-hemisphere autoradiography of 5-HT₁ B receptor densities in postmortem alcoholic brains
Storvik Markus, Häkkinen Merja, Tupala Erkki, Tiihonen Jari. 2012. Psychiatry research: neuroimaging. 202: 264-270 -
mGluR1/5 receptor densities in the brains of alcoholic subjects: A whole-hemisphere autoradiography study
Kupila Jukka, Kärkkäinen Olli, Laukkanen Virpi, Tupala Erkki, Tiihonen Jari, Storvik Markus. 2012. Psychiatry research: neuroimaging. 2013:212: 245-250 -
A nationwide cohort study of oral and depot antipsychotics after first hospitalization for schizophrenia
Tiihonen J, Haukka J, Taylor M, Haddad PM, Patel MX, Korhonen P. 2011. American journal of psychiatry. 168: 603-609 -
Add-on mirtazapine improves depressive symptoms in schizophrenia: a double-blind randomized placebo-controlled study with an open-label extension phase
Terevnikov V, Stenberg J-H, Tiihonen J, Joffe M, Burkin M, Tchoukhine E, Joffe G. 2011. Human psychopharmacology: clinical and experimental. 26: 188-193 -
Clinical relevance in Finnish population based studies in schzophrenia, with special reference to the Northern Finland 1966 Birth Cohort Study
Isohanni M, Miller B, Koivumaa H, Tiihonen J, Koponen H, Moilanen K, Tanskanen P, Penttilä M, Rannikko I, Culpepper N, Ghose S, Moilanen J, Rissanen I, Huhtaniska S, Ruonala P, Keskinen E, Hirvasniemi J, Leviäkangas A, Isohanni I, Alaräisänen A, Miettunen J, Jääskeläinen E. 2011. Psychiatria fennica. 42: 65-86 -
Cortex and amygdala morphology in psychopathy
Boccardi M, Frisoni GB, Hare RD, Cavedo E, MNajt P, Pievani M, Rasser PE, Laakso MP, Aronen HJ, Repo-Tiihonen E, Vaurio O, Thompson PM, Tiihonen J. 2011. Psychiatry research: neuroimaging. 193: 85-92 -
Costs of intensive psychiatric care for treatment-resistant minors
Paakkonen T, Tiihonen J, Paakkonen H, Hallikainen T, Ryynänen O-P, Kinnunen J. 2011. Journal of mental health policy and economics. 14: 149-156 -
Gender differences in brain serotonin transporter availability in panic disorder
Maron E, Tõru I, Hirvonen J, Tuominen L, Lumme V, Vasar V, Shlik J, Nutt DJ, Helin S, Någren K, Tiihonen J, Hietala J. 2011. Journal of psychopharmacology. 25: 952-959 -
Group psychoeducation for long-term offender patients with schizophrenia: An exploratory randomized controlled trial
Aho-Mustonen Kati, Tiihonen Jari, Repo-Tiihonen Eila, Ryynänen Olli-Pekka, Miettinen Raili & Räty Hannu. 2011. Criminal behaviour and mental health. 21: 163-176 -
Interrelationship between core interventions and core competencies of forensic psychiatric nursing in Finland
Tenkanen Helena, Tiihonen Jari, Repo-Tiihonen Eila, Kinnunen Juha. 2011. Journal of forensic nursing. 7: 32-39 -
Lastenpsykiatrian ja nuorisopsykiatrian erikoisalojen säilyttäminen on yhteiskunnallinen kysymys
Aalberg V, Arajärvi T, Haukkamaa K, Laukkanen E, Lehtonen J, Pylkkänen K, Taipale V, Tiihonen J. 2011. Lääkärilehti. 66: 3562-3563 -
More evidence on proneurocognitive effects of add-on mirtazapine in schizophrenia
Stenberg J-H, Terevnikov V, Joffe M, Tiihonen J, Tchoukhine E, Burkin M, Joffe G. 2011. Progress in neuro-psychopharmacology and biological psychiatry. 35: 1080-1086 -
Niuvanniemen nuoriso-osastolle ohjautuneiden potilaiden kotikuntien mielenterveyttä tukevien palvelujen tarjonta ja menot
Rissanen T, Tiihonen J, Paakkonen H, Hallikainen T, Ryynänen O-P, Kinnunen J. 2011. Sosiaalilääketieteellinen aikakauslehti. 48: 22-37 -
Oikeuspsykiatria
Tiihonen J. Teoksessa: Lönnqvist J, Henriksson M, Marttunen M, Partonen T(toim.) , 2011. Psykiatria. 9. uudistettu painos. s. 611-628. -
Psychopathy, PCL-R, and MAOA genotype as predictors of violent reconvictions
Tikkanen R, Auvinen-Lintunen L, Ducci F, Sjöberg RL, Goldman D, Tiihonen J, Ojansuu I, Virkkunen M. 2011. Psychiatry research. 185: 382-386 -
Päivittäistavarakaupoissa myytävien juomien alkoholipitoisuuden alentamisen vaikutus alkoholin kulutukseen ja kuolemiin
Tiihonen Jari, Kangasharju Aki, Mäkelä Pia, Saari Juho, Österberg Esa. 2011. VATT valmisteluraportit. . -
The patient- therapist interaction and the recognition of affects during the process of psychodynamic psychotherapy for depression
Ahola P, Valkonen-Korhonen M, Tolmunen T, Joensuu M, Lehto SM, Saarinen PI, Tiihonen J, Lehtonen J. 2011. American journal of psychotherapy. 65: 355-379 -
The place of observational studies in assessing the effectiveness of depot antipsychotics
Haddad PM, Tiihonen J, Haukka J, Taylor M, Patel MX, Korhonen P. 2011. Schizophrenia research. 131: 260-261 -
Abnormal hippocampal shape in offenders with psychopathy
Boccardi M, Ganzola R, Rossi R, Sabattoli F, Laakso MP, Repo-Tiihonen E, Vaurio O, Könönen M, Aronen HJ, Thompson PM, Frisoni GB, Tiihonen J. 2010. Human brain mapping. 31: 438-447 -
Dopamine transporter binding in females with panic disorder may vary with clinical status
Maron E, Nutt DJ, Kuikka J, Tiihonen J. 2010. Journal of psychiatric research. 44: 56-59 -
Effects of add-on mirtazapine on neurocognition in schisophrenia: a double-blind, randomized, placebo-controlled study
Stenberg J-H, Terevnikov V, Joffe M, Tiihonen J, Tchoukhine E, Burkin M, Joffe G. 2010. International journal of neuropsychopharmacology. 13: 433-441 -
Endogenous cannabinoids in post-mortem brains of Cloninger type 1 and 2 alcoholics
Lehtonen M, Storvik M, Tupala E, Hyytiä P, Tiihonen J & Callaway JC. 2010. European neuropsychopharmacology. 20: 245 - 252 -
Extrapyramidal side-effects and dopamine D2/3 receptor binding in substanta nigra
Tuppurainen H, Kuikka JT, Viinamäki H, Husso M, Tiihonen J. 2010. Nordic journal of psychiatry. 64: 233-238 -
Incidence of cancer and antidepressant medication: record linkage study
Haukka J, Sankila R, Klaukka T, Lonnqvist J, Niskanen L, Tanskanen J, Wahlbeck K & Tiihonen J. 2010. International journal of cancer. 126: 285-296 -
Incidence of cancer and statin usage - record linkage study
Haukka J, Sankila R, Klaukka T, Lonnqvist J, Niskanen L, Tanskanen A, Wahlbeck K &Tiihonen J. 2010. International journal of cancer. 126: 279-284 -
MAOA alters the effects of heavy drinking and childhood physical abuse on risk for severe impulsive acts of violence among alcoholic violent offenders
Tikkanen R, Ducci F, Goldman D, Holi M, Lindberg N, Tiihonen J, Virkkunen M. 2010. Alcoholism-clinical and experimental research. 35: 1-8 -
More evidence on additive antipsychotic effect of adjunctive mirtazapine in schizophrenia: an extension phase of a randomized controlled trial
Terevnikov V, Stenberg J-H, Joffe M, Tiihonen J, Burkin M, Tchoukhine E, Joffe G. 2010. Human psychopharmacology: clinical and experimental. 25: 431-438 -
Seasonal variation of seclusion incidents from violent and suicidal acts in forensic psychiatric patients
Paavola P, Tiihonen J. 2010. International journal of law and psychiatry. 33: 27-34 -
Serotonin-transporter-linked promoter region polymorphism and serotonin transporter binding in drug-naive patients with major depression
Joensuu M, Lehto SM, Tolmunen T, Saarinen PI, Valkonen-Korhonen M, Vanninen R, Ahola P, Tiihonen J, Kuikka J, Pesonen U, Lehtonen J. 2010. Psychiatry and clinical neurosciences. 64: 387-393 -
The intergenerational cycle of criminality - association with psychopathy
Repo-Tiihonen E, Tiihonen J, Lindberg N, Weizmann-Henelius G, Putkonen H, Häkkänen H. 2010. Journal of forensic sciences. 55: 116-120 -
11-year follow-up of mortality in patients with schizophrenia: a population-based cohort study (FIN11 study)
Tiihonen J, Lönnqvist J, Wahlbeck K, Klaukka T, Niskanen L, Tanskanen A, Haukka J. 2009. The Lancet. 374: 620-627 -
5-HT1A receptors in the frontal cortical brain areas in Cloninger type 1 and 2 alcoholics measured by whole-hemisphere autoradiography
Storvik M, Häkkinen M, Tupala E, Tiihonen J. 2009. Alcohol and alcoholism. 44: 2-7 -
Add-on mirtazapine enhances antipsychotic effect of first generation antipsychotics in schizophrenia: A double-blind, randomized, placebo-controlled trial
Joffe G, Terevnikov V, Joffe M, Stenberg J-H, Burkin M, Tiihonen J. 2009. Schizophrenia research. 108: 245-251 -
Altered hemispheric balance of temporal cortex dopamine D2/3 receptor binding in major depressive disorder
Lehto SM, Kuikka J, Tolmunen T, Hintikka J, Viinamäki H, Vanninen R, Koivumaa-Honkanen H, Honkalampi K, Tiihonen J. 2009. Psychiatry research: neuroimaging -
Antidepressant use and mortality in Finland: a register-linkage study from a nationwide cohort
Haukka J, Arffman M, Partonen T, Sihvo S, Elovainio M, Tiihonen J, Lönnqvist J, Keskimäki I. 2009. European journal of clinical pharmacology. 65: 715-720 -
Author's reply (to 11-year follow-up study of mortality in patients with schizophrenia: a population-based cohort study (FIN11 study)
Tiihonen J, on behalf of all authors. 2009. The Lancet -
Cardiac repolarization and striatal dopamine transporter function are interrelated
Kauppila E, Vanninen E, Kuusela T, Kaurijoki S, Karhunen L, Pietiläinen KH, Rissanen A, Kaprio J, Tiihonen J, Kuikka J, Kaurijoki S, Karhunen L. 2009. Nuclear medicine communications. 30: 713-717 -
Dopamine D2/3 receptor binding potential and occupancy in midbrain and temporal cortex by haloperidol, olanzapine and clozapine
Tuppurainen H, Kuikka JT, Viinamäki H, Husso M, Tiihonen J. 2009. Psychiatry and clinical neurosciences. 63: 529-537 -
Effects of MAOA-genotype, alcohol consumption, and aging on violent behavior
Tikkanen R, Sjöberg RL, Ducci F, Goldman D, Holi M, Tiihonen J, Virkkunen M. 2009. Alcoholism-clinical and experimental research. 33: 428-434 -
Low non-oxidative glucose metabolism and violent offending: An 8-year prospective follow-up study
Virkkunen M, Rissanen A, Franssila-Kallunki A, Tiihonen J. 2009. Psychiatry research. 168: 26-31 -
Predicting forensic admission among the mentally ill in a multinational setting: A Bayesian modelling approach
Soini EJO, Rissanen T, Tiihonen J, Hodgins S, Eronen M, Ryynänen O-P. 2009. Data and knowledge engineering. 68: 1427-1440 -
Premorbid personality factors in schizophrenia and bipolar disorder: Results from a large cohort study of male conscripts
Lönnqvist J-E, Verkasalo M, Haukka J, Nyman K, Tiihonen J, Laaksonen I, Leskinen J, Lönnqvist J, Henriksson M. 2009. Journal of abnormal psychology. 118: 418-423 -
Psykopatian etiologia
Repo-Tiihonen E, Holi M, Tiihonen J. Teoksessa: Häkkänen-Nyholm H(toim.) , 2009. Psykopatia. s. 99-111. Edita Prima -
Recidivistic offending and mortality in alcoholic violent offenders: A prospective follow-up study
Tikkanen R, Holi M, Lindberg N, Tiihonen J, Virkkunen M. 2009. Psychiatry research. 168: 18-25 -
The efficacy of lamotrigine in clozapine-resistant schizophrenia: A systemic review and meta-analysis
Tiihonen J, Wahlbeck K, Kiviniemi V. 2009. Schizophrenia research. 109: 10-14 -
Association between medication and risk of suicide, attempted suicide and death in nationwide cohort of suicidal patients with schizophrenia
Haukka J, Tiihonen J, Härkänen T, Lönnqvist J. 2008. Pharmacoepidemiology and drug safety. 17: 686-696 -
Association of serotonin transporter promoter regulatory region polymorphism and cerebral activity to visual presentation of food
Kaurijoki S, Kuikka JT, Niskanen E, Carlson S, Pietiläinen KH, Pesonen U, Kaprio JM, Rissanen A, Tiihonen J, Karhunen L, Karhunen L. 2008. Clinical physiology and functional imaging. 28: 270-276 -
Autoradiographic characterization of alpha 2C-adrenoceptors in the human striatum
Fagerholm V, Rokka J, Nyman L, Sallinen J, Tiihonen J, Tupala E, Haaparanta M, Hietala J. 2008. Synapse. 62: 508-515 -
Brain anatomy of persistent violent offenders: more rather than less
Tiihonen J, Rossi R, Laakso MP, Hodgins S, Testa C, Perez J, Repo-Tiihonen E, Vaurio O, Soininen H, Aronen HJ, Könönen M, Thompson PM, Frisoni G, Könönen M, Soininen H. 2008. Psychiatry research: neuroimaging. 163: 201-212 -
Changes in midbrain serotonin transporter availability in atypically depressed subjects after one year of psychotherapy
Lehto SM, Tolmunen T, Joensuu M, Saarinen PI, Valkonen-Korhonen M, Vanninen R, Ahola P, Tiihonen J, Kuikka J, Lehtonen J. 2008. Progress in neuro-psychopharmacology and biological psychiatry. 32: 229-237 -
Characterization of metabolic syndrome among forensic psychiatric inpatients
Ojala K, Niskanen L, Tiihonen J, Paavola P, Putkonen A, Repo-Tiihonen E. 2008. Journal of forensic psychiatry and psychology. 19: 33-51 -
Correlation between the SERT binding densities in hypothalamus and amygdala in Cloninger type 1 and 2 alcoholics
Storvik M, Haukijärvi T, Tupala E, Tiihonen J. 2008. Alcohol and alcoholism. 43: 25-30 -
Cortical dopamine D1 receptors in type 1 and type 2 alcoholics measured with human whole hemisphere autoradiography
Tupala E, Tiihonen J. 2008. Psychiatry research: neuroimaging. 162: 1-9 -
Midbrain serotonin and striatum dopamine transporter binding in double depression: a one-year follow-up study
Lehto SM, Tolmunen T, Kuikka J, Valkonen -Korhonen M, Joensuu M, Saarinen PI, Vanninen R, Ahola P, Tiihonen J, Lehtonen J. 2008. Neuroscience letters. 441: 291-295 -
Pharmacotherapy of methamphetamine addiction: an update
Elkashef A, Vocci F, Hanson G, White J, Wickes W, Tiihonen J. 2008. Substance abuse. 29: 31-49 -
Statins are effective in treating dyslipidemia among psychiatric patiens using second-generation antipsychotic agents
Ojala K, Repo-Tiihonen E, Tiihonen J, Niskanen L. 2008. Journal of psychopharmacology. 22: 33-38 -
Striatal dopaminergic terminals in type 1 and type 2 alcoholics measured with [3H]dihydrotetrabenazine and human whole himisphere autoradiography
Tupala E, Häkkinen M, Storvik M, Tiihonen J. 2008. Psychiatry research: neuroimaging. 163: 70-75 -
Temporal cortex dopamine D2/3 receptor binding in major depression
Lehto S, Kuikka J, Tolmunen T, Hintikka J, Viinamäki H, Vanninen R, Haatainen K, Koivumaa-Honkanen H, Honkalampi K, Tiihonen J. 2008. Psychiatry and clinical neurosciences. 62: 345-348 -
Vagushermostimulaattori hoitoresistentin depression hoidossa
Kaila M, Lehtonen M-L, Kärkkäinen M, Tiihonen J. 2008. Lääkärilehti. 63: 271-273 -
A comparison of aripiprazole, methylphenidate, and placebo for amphetamine dependence
Tiihonen J, Kuoppasalmi K, Föhr J, Tuomola P, Kuikanmäki O, Vorma H, Sokero P, Haukka J, Meririnne E. 2007. American journal of psychiatry. 164: 160-162 -
A comparison of general adult and forensic patients with schizophrenia living in the community
Hodgins S, Müller-Isberner R, Tiihonen J, Repo-Tiihonen E, Eronen M, Eaves D, Hart S, Webster C, Levander S, Tuninger E, Ross D, Kronstrand R. 2007. International journal of forensic mental health. 6: 65-77 -
A multisite study of community treatment programs for mentally ill offenders with major mental disorders. Design, measures, and the forensic sample
Hodgins S, Tengström A, Eriksson A, Österman R, Kronstrand R, Eavek D, Hart S, Webster C, Ross D, Levin A, Levander S, Tuninger E, Müller-Isberner R, Freese R, Tiihonen J, Kotilainen I, Repo-Tiihonen E, Väänänen K, Eronen M, Vokkolainen A. 2007. Criminal justice and behavior. 34: 211-228 -
Amygdala serotonin transporters in alcoholics measured by whole hemisphere autoradiography
Storvik M, Tiihonen J, Haukijärvi T, Tupala E. 2007. Synapse. 61: 629-636 -
Body size and violent offending among males in the Northern Finland 1966 birth cohort
Ikäheimo P, Räsänen P, Hakko H, Hartikainen A-L, Laitinen J, Hodgins S, Tiihonen J. 2007. Social psychiatry and psychiatric epidemiology. 42: 845-850 -
Energy substrate metabolism among habitually violent alcoholic offenders having antisocial personality disorder
Virkkunen M, Rissanen A, Naukkarinen H, Franssila-Kallunki A, Linnoila M, Tiihonen J. 2007. Psychiatry research. 150: 287-295 -
Functional COMT Val158Met polymorphism, risk of acute coronary events and serum homocysteine: the Kuopio Ischaemic Heart Disease Risk Factor Study
Voutilainen S, Tuomainen TP, Korhonen M, Mursu J, Virtanen JK, Happonen P, Alftan G, Erlund I, North KE, Mosher MJ, Kauhanen J, Tiihonen J, Kaplan GA, Salonen JT. 2007. PLoS ONE. 2: e181 -
Masennuslääkkeet ja itsetuhokäyttäytyminen
Tiihonen J. 2007. Lääkärilehti -
Näkyykö pahuus aivoista?
Tiihonen J. 2007. Duodecim. 123: 2367-2368 -
Oikeuspsykiatria
Tiihonen J. Teoksessa: Lönnqvist J, Heikkinen M, Henriksson M, Marttunen M, Partonen T(toim.) , 2007. Psykiatria. 5. uud. p.. s. 650-667. Duodecim -
Reduced midbrain serotonin transporter availability in drug-naive patients with depression measured by SERT-specific [(123)I] nor-beta-CIT SPECT imaging
Joensuu M, Tolmunen T, Saarinen PI, Tiihonen J, Kuikka J, Ahola P, Vanninen R, Lehtonen J. 2007. Psychiatry research: neuroimaging. 154: 125-131 -
Transmission of violent offending and crime across three generations
Putkonen A, Ryynänen O-P, Eronen M, Tiihonen J. 2007. Social psychiatry and psychiatric epidemiology. 42: 94-9 -
Violent persons with schizophrenia and comorbid disorders: a functional magnetic resonance imaging study
Joyal CC, Putkonen A, Mancini-Marïe A, Hodgins S, Kononen M, Boulay L, Pihlajamaki M, Soininen H, Stip E, Tiihonen J, Aronen HJ, Könönen M. 2007. Schizophrenia research. 91: 97-102 -
Antidepressants and the risk of suicide, attempted suicide, and overall mortality in a nationwide cohort
Tiihonen J, Lönnqvist J, Wahlbeck K, Klaukka T, Tanskanen A, Haukka J. 2006. Archives of general psychiatry. 63: 1358-1367 -
Effectiveness of antipsychotic treatments in a nationwide cohort of patients in community care after first hospitalisation due to schizophrenia and schizoaffective disorder: observational follow-up study
Tiihonen J, Walhbeck K, Lönnqvist J, Klaukka T, Ioannidis JP, Volavka J, Haukka J. 2006. BMJ (INTERNATIONAL). 333: 224 -
Fatal agranulocytosis 4 years after discontinuation of clozapine
Tiihonen J. 2006. American journal of psychiatry -
Lower serotonin transporter binding in caudate in alcoholics
Storvik M, Tiihonen J, Haukijärvi T, Tupala E. 2006. Synapse. 59: 144-151 -
Midbrain binding of (123I)nor-beta-CIT in atypical depression
Lehto S, Tolmunen T, Joensuu M, Saarinen PI, Vanninen R, Ahola P, Tiihonen J, Kuikka J, Lehtonen J. 2006. Progress in neuro-psychopharmacology and biological psychiatry. 30: 1251-1255 -
Midbrain dopamine D2/3 receptor binding in schizophrenia
Tuppurainen H, Kuikka JT, Laakso MP, Viinamäki H, Husso M, Tiihonen J, Laakso MP. 2006. European archives of psychiatry and clinical neuroscience. 256: 382-387 -
Visualization of the cortical dopamine transporter in type 1 and 2 alcoholics with human whole hemisphere autoradiography
Tupala E, Halonen P, Tiihonen J. 2006. European neuropsychopharmacology. 16: 552-560 -
An outcome of psychodynamic psychotherapy: a case study of the change in serotonin transporter binding and the activation of the dream screen
Saarinen PI, Lehtonen J, Joensuu M, Tolmunen T, Ahola P, Vanninen R, Kuikka J, Tiihonen J. 2005. American journal of psychotherapy. 59: 61-73 -
Effects of venlafaxine treatment on clozapine plasma levels in schizophrenic patients
Repo-Tiihonen E, Eloranta A, Hallikainen T, Tiihonen J. 2005. Neuropsychobiology. 51: 173-176 -
Glutamatergic drugs for schizophrenia: a systematic review and meta-analysis
Tuominen HJ, Tiihonen J, Wahlbeck K. 2005. Schizophrenia research. 72: 225-234 -
Premorbid intellectual functioning in bipolar disorder and schizophrenia: Results from a cohort study of male conscripts
Tiihonen J, Haukka J, Henriksson M, Cannon M, Kieseppä T, Laaksonen I, Sinivuo J, Lönnqvist J. 2005. American journal of psychiatry. 162: 1904-1910 -
Seasonal variations in [3H]citalopram platelet binding between healthy controls and violent offenders in Finland
Callaway J, Storvik M, Halonen P, Hakko H, Räsänen P, Tiihonen J. 2005. Human psychopharmacology: clinical and experimental. 20: 467-472 -
Striatal dopamine D1 receptors in type 1 and 2 alcoholics measured with human whole hemisphere autoradiography
Tupala E, Tiihonen J. 2005. Brain research. 1031: 20-29 -
The consequences of Conduct Disorder for males who develop schizophrenia: Associations with criminality, aggressive behavior, substance use, and psychiatric services
Hodgins S, Tiihonen J, Ross D. 2005. Schizophrenia research. 78: 323-335 -
Topiramate add-on in treatment-resistant schizophrenia: a randomized, double-blind, placebo-controlled, crossover trial
Tiihonen J, Halonen P, Wahlbeck K, Repo-Tiihonen E, Hyvärinen S, Eronen M, Putkonen H, Takala P, Mehtonen O-P, Puck M, Oksanen J, Koskelainen P, Joffe G, Aer J, Hallikainen T, Ryynänen O-P, Tupala E. 2005. Journal of clinical psychiatry. 66: 1012-1015 -
Verklighetstrogen utvärderande forskning med hjälp av nationella datariserade register
Tiihonen J. 2005. Finska läkaresällskapets handlingar. 165: 26-27 -
Visualisation of the cortical dopamine D3 receptors in alcoholics and controls with human whole-hemisphere autoradiography
Tupala E, Hall H, Tiihonen J. 2005. Psychopharmacology. 181: 412-413 -
123I-beta-CIT binding and recovery from depression. A six-month follow-up study
Laasonen-Balk T, Viinamäki H, Kuikka JT, Husso-Saastamoinen M, Lehtonen J, Tiihonen J. 2004. European archives of psychiatry and clinical neuroscience. 254: 152-155 -
A controlled study of tryptophan and cortisol in violent offenders
Soderstrom H, Blennow K, Forsman A, Liesivuori J, Pennanen S, Tiihonen J. 2004. Journal of neural transmission. 111: 1605-1610 -
Brain serotonin 1A receptor binding in bulimia nervosa
Tiihonen J, Keski-Rahkonen A, Löppönen M, Muhonen M, Kajander J, Allonen T, Någren K, Hietala J, Rissanen A. 2004. Biological psychiatry. 55: 871-873 -
Characteristics and circumstances of homicidal acts committed by offenders with schizophrenia
Joyal CC, Putkonen A, Paavola P, Tiihonen J. 2004. Psychological medicine. 34: 433-442 -
Comorbid personality disorders and substance use disorders of mentally I11 homide offenders: A structural clinical study on dual and triple diagnoses
Putkonen A, Kotilainen I, Joyal CC, Tiihonen J. 2004. Schizophrenia bulletin. 30: 59-72 -
Cortical dopamine D2 receptors in type 1 and 2 alcoholics measured with human whole hemisphere autoradiography
Tupala E, Hall H, Halonen P, Tiihonen J. 2004. Synapse. 54: 129-137 -
Distribution of 5-HT7 receptors in the human brain: a preliminary autoradiographic study using [3H]SB-269970
Varnäs K, Thomas DR, Tupala E, Tiihonen J, Hall H. 2004. Neuroscience letters. 367: 313-316 -
Dopamine and alcoholism: neurobiological basis of ethanol abuse
Tupala E, Tiihonen J. 2004. Progress in neuro-psychopharmacology and biological psychiatry. 28: 1221-1247 -
Elevated midbrain serotonin transporter availability in mixed mania : a case report
Tolmunen T, Joensuu M, Saarinen PI, Mussalo H, Ahola P, Vanninen R, Kuikka J, Tiihonen J, Lehtonen J. 2004. Bmc psychiatry. 4: [13 September 2004] -
MRI volumetry of the vermis and cerebellar hemispheres in men with schizophrenia
Joyal CC, Pennanen C, Tiihonen E, Laakso MP, Tiihonen J, Aronen HJ, Laakso MP. 2004. Psychiatry research: neuroimaging. 131: 115-124 -
Miksi pakon käyttö vaihtelee niin paljon psykiatrisessa hoidossa?
Tiihonen J. 2004. Lääkärilehti -
Omega-3-rasvahapot -uusi lisähoito masennukseen?
Tanskanen A, Tiihonen J. 2004. Duodecim -
Reduced brain serotonin transporter binding in patients with panic disorder
Maron E, Kuikka JT, Shlik J, Vasar V, Vanninen E, Tiihonen J. 2004. Psychiatry research: neuroimaging. 132: 173-181 -
SPECT imaging of serotonin transporter binding in patients with generalized anxiety disorder
Maron E, Kuikka JT, Ulst K, Tiihonen J, Vasar V, Shlik J. 2004. European archives of psychiatry and clinical neuroscience. 254: 392-396 -
Stimulanttiriippuvuuden hoidot
Tiihonen J. 2004. Duodecim -
Alcoholics show altered histaminergic neurotransmission in several cortical areas - preliminary report
Alakärppä K, Tupala E, Mantere T, Särkioja T, Räsänen P, Tarhanen J, Tiihonen J, Tuomisto L. 2003. INFLAMMATION RESEARCH. SUPPLEMENT. 52: 37-38 -
Different effect of age on dopamine transporters in the dorsal and ventral striatum of controls and alcoholics
Tupala E, Hall H, Bergström K, Mantere T, Räsänen P, Särkioja T, Hiltunen J, Tiihonen J. 2003. Synapse. 48: 205-211 -
Dopamine D2 receptors and transporters in type 1 and 2 alcoholics measured with human whole hemisphere autoradiography
Tupala E, Hall H, Bergström K, Mantere T, Räsänen P, Särkioja T, Tiihonen J. 2003. Human brain mapping. 20: 91-102 -
Dopamine receptors and transporters in the brain reward circuits of type 1 and 2 alcoholics measured with human whole hemisphere autoradiography
Tupala E, Hall H, Mantere T, Räsänen P, Särkioja T, Tiihonen J. 2003. Neuroimage. 19: 145-155 -
Ethanol consumption and DRD2 gene TaqI A polymorphism among socially drinking males
Hallikainen T, Hietala J, Kauhanen J, Pohjalainen T, Syvälahti E, Salonen JT, Tiihonen J. 2003. American journal of medical genetics. Part A. 119A: 152-155 -
Extrastriatal dopamine D2/3 receptor density and distribution in drug-naive schizophrenic patients
Tuppurainen H, Kuikka J, Viinamäki H, Husso-Saastamoinen M, Bergström K, Tiihonen J. 2003. Molecular psychiatry. 8: 453-455 -
Lamotrigine in treatment-resistant schizophrenia: a randomized placebo-controlled crossover trial
Tiihonen J, Hallikainen T, Ryynänen O-P, Repo-Tiihonen E, Kotilainen I, Eronen M, Toivonen P, Wahlbeck K, Putkonen A. 2003. Biological psychiatry. 54: 1241-1248 -
The amygdala and schizophrenia: A volumetric magnetic resonance imaging stury in first-episode, neuroleptic-naive patients
Joyal CC, Laakso MP, Tiihonen J, Syvälahti E, Vilkman H, Laakso A, Alakare B, Räkköläinen V, Salokangas RKR, Hietala J. 2003. Biological psychiatry. 54: 1302-1304 -
Total plasma L-tryptophan, free L-tryptophan and competing amino acid levels in a homicidal male adolescent with conduct disorder
Virkkunen M, Ebeling H, Moilanen I, Tani P, Pennanen S, Liesivuori J, Tiihonen J. 2003. Acta psychiatrica scandinavica. 108: 244-247 -
Treatment improves serotonin transporter binding and reduces binge eating
Tammela LI, Rissanen A, Kuikka JT, Karhunen LJ, Bergström KA, Repo-Tiihonen E, Naukkarinen H, Vanninen E, Tiihonen J, Uusitupa M. 2003. Psychopharmacology. 170: 89-93 -
A volumetric MRI study of the entorhinal cortex in first episode neuroleptic-naive schizophrenia
Joyal CC, Laakso MP, Tiihonen J, Syvälahti E, Vilkman H, Laakso A, Alakare B, Räkköläinen V, Salokangas RKR, Hietala J. 2002. Biological psychiatry. 51: 1005-1007 -
Analysis of monoamine oxidase A (MAOA) promoter polymorphism in Finnish male alcoholics
Saito T, Lachman HM, Diaz L, Hallikainen T, Kauhanen J, Salonen JT, Ryynanen O-P, Karvonen MK, Syvalahti E, Pohjalainen T, Hietala J, Tiihonen J. 2002. Psychiatry research. 109: 113-119 -
Effect of alcohol abuse on human brain histamine and tele-methylhistamine
Alakärppä K, Tupala E, Mantere T, Särkioja T, Räsänen P, Tarhanen J, Tiihonen J, Tuomisto L. 2002. INFLAMMATION RESEARCH. SUPPLEMENT. 51: 40-41 -
Is occupation relevant in suicide?
Koskinen O, Pukkila K, Hakko H, Tiihonen J, Väisänen E, Särkioja T, Räsänen P. 2002. Journal of affective disorders. 70: 197-203 -
Prefrontal volumes in habitually violent subjects with antisocial personality disorder and type 2 alcoholism
Laakso MP, Gunning-Dixon F, Vaurio O, Repo-Tiihonen E, Soininen H, Tiihonen J. 2002. Psychiatry research: neuroimaging. 114: 95-102 -
Seasonal variation in specific methods of suicide: a national register study of 20 234 Finnish people
Räsänen P, Hakko H, Jokelainen J, Tiihonen J. 2002. Journal of affective disorders. 71: 51-59 -
Seclusion treatment measures and serum cholesterol levels among Finnish male forensic psychiatric patients
Repo-Tiihonen E, Paavola P, Halonen P, Tiihonen J, Repo-Tiihonen E. 2002. JOURNAL OF FORENSIC PSYCHIATRY. 13: 157-165 -
Serotonin transporter distribution and density in the cerebral cortex of alcoholic and nonalcoholic comparison subjects: a whole-hemisphere autoradiography sudy
Mantere T, Tupala E, Hall H, Särkioja T, Räsänen P, Bergström K, Callaway J, Tiihonen J. 2002. American journal of psychiatry. 159: 599-606 -
Serum lipid levels and violence among Finnish male forensic psychiatric patients
Paavola P, Repo-Tiihonen E, Tiihonen J. 2002. JOURNAL OF FORENSIC PSYCHIATRY. 13: 555-568 -
The quantitative risk of violent crime and criminal offending: a case-control study among the offspring of recidivistic Finnish homicide offenders
Putkonen A, Ryynänen O-P, Eronen M, Tiihonen J. 2002. Acta psychiatrica scandinavica, supplement. 106: 54-57 -
Total serum cholesterol level, violent criminal offences, suicidal behavior, mortality and the appearance of conduct disorder in Finnish male criminal offenders with antisocial personality disorder
Repo-Tiihonen E, Halonen P, Tiihonen J, Virkkunen M. 2002. European archives of psychiatry and clinical neuroscience. 252: 8-11 -
Use of statistical techniques in studies of suicide seasonality, 1970 to 1997
Hakko H, Räsänen P, Tiihonen J, Nieminen P. 2002. Suicide and life-threatening behavior. 32: 191-208 -
A morphometric MRI study of the hippocampus in first-episode, neuroleptic-naive schizophrenia
Laakso MP, Tiihonen J, Syvälahti E, Vilkman H, Laakso A, Alakare B, Räkköläinen V, Salokangas RKR, Koivisto E, Hietala J. 2001. Schizophrenia research. 50: 3-7 -
Altered frontal lobe function suggested by source analysis of event-related potentials in impulsive violent alcoholics
Tarkka IM, Karhu J, Kuikka J, Pääkkönen A, Bergström K, Partanen J, Tiihonen J. 2001. Alcohol and alcoholism. 36: 323-328 -
Characterization of gamma-aminobutyrate type A receptors with atypical coupling between agonist and convulsant binding sites in discrete brain regions
Sinkkonen ST, Uusi-Oukari M, Tupala E, Särkioja T, Tiihonen J, Panula P, Lüddens H, Korpi ER. 2001. MOLECULAR BRAIN RESEARCH. 86: 168-178 -
Cluster C personality disorder has no independent effect on stratial dopamine transporter densities in major depression
Laasonen-Balk T, Viinamäki H, Kuikka J, Husso-Saastamoinen M, Lehtonen J, Halonen P, Tiihonen J. 2001. Psychopharmacology -
Dopamine D2/D3-receptor and transporter densities in nucleus accumbens and amygdala of type 1 and 2 alcoholics
Tupala E, Hall H, Bergström K, Särkioja T, Räsänen P, Mantere T, Callaway J, Hiltunen J, Tiihonen J. 2001. Molecular psychiatry. 6: 261-267 -
Dopamine transporter density and novelty seeking among alcoholics
Laine TPJ, Ahonen A, Räsänen P, Tiihonen J. 2001. Journal of addictive diseases. 20: 91-96 -
Dopamine transporter in vitro binding and in vivo imaging in the brain
Bergström KA, Tupala E, Tiihonen J. 2001. Basic and clinical pharmacology and toxicology. 88: 287-293 -
Effects of ageing on serotonin transporters in healthy females
Kuikka JT, Tammela L, Bergström KA, Karhunen L, Uusitupa M, Tiihonen J. 2001. European journal of nuclear medicine and molecular imaging. 28: 911-913 -
Free L-tryptophan plasma levels in antisocial violent offenders
Tiihonen J, Virkkunen M, Räsänen P, Pennanen S, Sainio E-L, Callaway J, Halonen P, Liesivuori J. 2001. Psychopharmacology. 157: 395-400 -
Measurement of the striatal dopamine transporter density and heterogeneity in type 1 alcoholics using human whole hemisphere autoradiography
Tupala E, Kuikka JT, Hall H, Bergström K, Särkioja T, Räsänen P, Mantere T, Hiltunen J, Vepsäläinen J, Tiihonen J. 2001. Neuroimage. 14: 87-94 -
Mortality of antisocial male criminals
Repo-Tiihonen E, Virkkunen M, Tiihonen J. 2001. JOURNAL OF FORENSIC PSYCHIATRY. 12: 677-683 -
Oikeuspsykiatria
Tiihonen J. Teoksessa: Lönnqvist J, Heikkinen M, Henriksson M, Marttunen M, Partonen T(toim.) , 2001. Psykiatria. 2. uud. p.. s. 746-761. Duodecim -
Psychopathy and the posterior hippocampus
Laakso MP, Vaurio O, Koivisto E, Savolainen L, Eronen M, Aronen HJ, Hakola P, Repo E, Soininen H, Tiihonen J. 2001. Behavioural brain research. 118: 187-193 -
Recidivistic violent behavior and axis I and axis II disorders
Tiihonen J. Teoksessa: Pinard G-F, Pagani L(toim.) , 2001. Clinical Assessment of Dangerousness: Empirical Contributions. s. 121-135. Cambridge University Press -
Reduced serotonin transporter binding in binge eating women
Kuikka JT, Tammela L, Karhunen L, Rissanen A, Bergström KA, Naukkarinen H, Vanninen E, Karhu J, Lappalainen R, Repo-Tiihonen E, Tiihonen J, Uusitupa M. 2001. Psychopharmacology. 155: 310-314 -
SPECT and neuropsychological performance in severe depression treated with ECT
Mervaala E, Könönen M, Föhr J, Husso-Saastamoinen M, Valkonen-Korhonen M, Kuikka JT, Viinamäki H, Tammi A-K, Tiihonen J, Partanen J, Lehtonen J. 2001. Journal of affective disorders. 66: 47-58 -
The A1 allele of the D2 dopamine receptor gene is associated with high dopamine transporter density in detoxified alcoholics
Laine TPJ, Ahonen A, Räsänen P, Pohjalainen T, Tiihonen J, Hietala J. 2001. Alcohol and alcoholism. 36: 262-265 -
A volumetric MRI study of the hippocampus in type 1 and 2 alcoholism
Laakso MP, Vaurio O, Savolainen L, Repo E, Soininen H, Aronen HJ, Tiihonen J. 2000. Behavioural brain research. 109: 177-186 -
Aging and homicide rates
Paanila J, Eronen M, Hakola P, Tiihonen J. 2000. Journal of forensic sciences. 45: 390-391 -
Aivojen toiminnallinen kuvantaminen psykiatriassa
Karhu J, Kuikka J, Tiihonen J. 2000. Duodecim. 116: 409-415 -
Association between the functional polymorphism of catechol-0-methyltransferase gene and alcohol consumption among social drinkers
Kauhanen J, Hallikainen T, Tuomainen T-P, Koulu M, Karvonen MK, Salonen JT, Tiihonen J. 2000. Alcoholism-clinical and experimental research. 24: 135-139 -
Benzodiazepine receptor density in major depression
Laasonen-Balk T, Viinamäki H, Kuikka J, Lehtonen J, Husso-Saastamoinen M, Mervaala E, Partanen J, Tiihonen J. 2000. Nordic journal of psychiatry. 54: 361-363 -
CYP2A6 genotype and smoking
Tiihonen J, Pesonen U, Kauhanen J, Koulu M, Hallikainen T, Leskinen L, Salonen JT. 2000. Molecular psychiatry. 5: 347-348 -
Dopamine-transporter density in nucleus accumbens of type-1 alcoholics
Tupala E, Hall H, Särkioja T, Räsänen P, Tiihonen J. 2000. The Lancet. 355: 380 -
Ethanol modulates evoked dopamine release in mouse nucleus accumbens: dependence on social stress and dose
Yavich L, Tiihonen J. 2000. European journal of pharmacology. 401: 365-373 -
Forensic psychiatric organization in Finland
Eronen M, Repo E, Vartiainen H, Tiihonen J. 2000. International journal of law and psychiatry. 23: 541-546 -
In vivo voltammetry with removable carbon fibre electrodes in freely-moving mice: dopamine release during intracranial self-stimulation
Yavich L, Tiihonen J. 2000. Journal of neuroscience methods. 104: 55-63 -
Lack of association between the functional variant of the catechol-o-methyltransferase (COMT) gene and early-onset alcoholism associated with severe antisocial behavior
Hallikainen T, Lachman H, Saito T, Volavka J, Kauhanen J, Salonen JT, Ryynänen O-P, Koulu M, Karvonen MK, Pohjalainen T, Syvälahti E, Hietala J, Tiihonen J. 2000. American journal of medical genetics. Part A. 96: 348-352 -
Metabolism of (123I)epidepride may affect brain dopamine D2 receptor imaging with single-photon emission tomography
Bergström KA, Yu M, Kuikka JT, Åkerman KK, Hiltunen J, Lehtonen J, Halldin C, Tiihonen J. 2000. European journal of nuclear medicine and molecular imaging. 27: 206-208 -
Oikeuspsykiatria
Tiihonen J, Hakola P. Teoksessa: Penttilä A, Hirvonen J, Saukko P, Karhunen PJ(toim.) , 2000. Oikeuslääketiede. 1. p.. s. 315-334. Duodecim -
Patterns of dopamine overflow in mouse nucleus accumbens during intracranial self-stimulation
Yavich L, Tiihonen J. 2000. Neuroscience letters. 293: 41-44 -
Pharmacological intervention for preventing violence among the mentally ill with secondary alcohol- and drug-use disorders
Tiihonen J, Swartz MS. Teoksessa: Hodgins S(toim.) , 2000. Violence among the Mentally Ill: Effective Treatments and Management Strategies. s. 171-191. Kluwer -
Pharmacological treatments for personality disordered offenders
Tiihonen J. Teoksessa: Hodgins S, Müller-Isberner R(toim.) , 2000. Violence, Crime and Mentally Disordered Offenders: Concepts and Methods for Effective Treatment and Prevention. s. 177-192. John Wiley & Sons -
Quantitative MRI of the hippocampus and amygdala in severe depression
Mervaala E, Föhr J, Könönen M, Valkonen-Korhonen M, Vainio P, Partanen K, Partanen J, Tiihonen J, Viinamäki H, Karjalainen A-K, Lehtonen J. 2000. Psychological medicine. 30: 117-125 -
Regional cerebral blood flow during exposure to food in obese binge eating women
Karhunen LJ, Vanninen EJ, Kuikka JT, Lappalainen RI, Tiihonen J, Uusitupa MIJ. 2000. Psychiatry research: neuroimaging. 99: 29-42 -
Specific binding and laterality of human extrastriatal dopamine D2/D3 receptors in late onset type 1 alcoholic patients
Kuikka JT, Repo E, Bergström KA, Tupala E, Tiihonen J. 2000. Neuroscience letters. 292: 57-59 -
Suicidal behavior in patients with schizophrenia is related to COMT polymorphism
Nolan KA, Volavka J, Czobor P, Cseh A, Lachman H, Saito T, Tiihonen J, Putkonen A, Hallikainen T, Kotilainen I, Räsänen P, Isohanni M, Järvelin M-R, Karvonen MK. 2000. Psychiatric genetics. 10: 117-124 -
Weather conditions and violent behavior
Tiihonen J, Callaway J, Storvik M, Räsänen P, Repo E, Hakko H, Väisänen E, Mantere T. Teoksessa: de Dear R, Kalma J, Oke T, Auliciems A(toim.) , 2000. Biometeorology and Urban Climatology at the Turn of the Millennium. Selected Papers from the Conference ICB-ICUC'99.. s. 155-156. World Meterological Organization -
Altered parallel auditory processing in schizophrenia patients
Pekkonen E, Huotilainen M, Katila H, Karhu J, Näätänen R, Tiihonen J. 1999. Schizophrenia bulletin. 25: 601-607 -
Association between low activity serotonin transporter promoter genotype and early onset alcoholism with habitual impulsive violent behavior
Hallikainen T, Saito T, Lachman HM, Volavka J, Pohjalainen T, Ryynänen O-P, Kauhanen J, Syvälahti E, Hietala J, Tiihonen J. 1999. Molecular psychiatry. 4: 385-388 -
Association between the functional variant of the catechol-O-methyltransferase (COMT) gene and type 1 alcoholism
Tiihonen J, Hallikainen T, Lachman H, Saito T, Volavka J, Kauhanen J, Salonen JT, Ryynänen O-P, Koulu M, Karvonen MK, Pohjalainen T, Syvälahti E, Hietala J. 1999. Molecular psychiatry. 4: 286-289 -
Comparison of iodine-123 labelled nor-beta-CIT and beta-CIT as potential radioligands for serotonin transporter imaging
Kuikka JT, Bergström KA, Åkerman K, Tiihonen J. Teoksessa: Bergmann H, Köhn H, Sinzinger H(toim.) , 1999. Radioactive Isotopes in Clinical Medicine and Research XXIII. Proceedings of the 23rd International Badgastein Symposium. s. 25-30. Birkhäuser -
Dopamine transporter and D2-receptor density in late-onset alcoholism
Repo E, Kuikka JT, Bergström KA, Karhu J, Hiltunen J, Tiihonen J. 1999. Psychopharmacology. 147: 314-318 -
Dopamine transporter availability and depressive symptoms during alcohol withdrawal
Laine TPJ, Ahonen A, Räsänen P, Tiihonen J. 1999. Psychiatry research: neuroimaging. 90: 153-157 -
First evaluation in humans of (123I)PE2I: a selective radioligand for visualization of the striatal dopamine transporter density
Bergström KA, Kuikka JT, Emond P, Hiltunen J, Halldin C, Guilloteau D, Mauclaire L, Yu M , Karhu J , Tupala E, Tiihonen J. Teoksessa: Bergmann H, Köhn H, Sinzinger H(toim.) , 1999. Radioactive Isotopes in Clinical Medicine and Research XXIII. Proceedings of the 23rd International Badgastein Symposium. s. 19-23. Birkhäuser -
Iodine-123 labelled PE2I for dopamine transporter imaging: influence of age in healthy subjects
Kuikka JT, Tupala E, Bergström KA, Hiltunen J, Tiihonen J. 1999. European journal of nuclear medicine and molecular imaging. 26: 1486-1488 -
Letter to the editor (to Is a large body size during childhood a risk factor for later aggression?)
Räsänen P, Hakko H, Järvelin M-R, Tiihonen J. 1999. Archives of general psychiatry -
Maternal smoking during pregnancy and risk of criminal behavior among adult male offspring in the Northern Finland 1966 birth cohort
Räsänen P, Hakko H, Isohanni M, Hodgins S, Järvelin M-R, Tiihonen J. 1999. American journal of psychiatry. 156: 857-862 -
Mortality among habitually violent offenders
Paanila J, Hakola P, Tiihonen J. 1999. Forensic science international. 100: 187-191 -
Oikeuspsykiatria
Tiihonen J. Teoksessa: Lönnqvist J, Heikkinen M, Henriksson M, Marttunen M, Partonen T(toim.) , 1999. Psykiatria. s. 712-731. Duodecim -
Outcome of different types of long-term antidepressant treatments: a 3-year follow-up study of 14 182 patients
Räsänen P, Hakko H, Jokelainen J, Tiihonen J. 1999. Journal of affective disorders. 55: 67-71 -
Pindolol and major affective disorders: a three-year follow-up study of 30,485 patients
Räsänen P, Hakko H, Tiihonen J. 1999. Journal of clinical psychopharmacology. 19: 297-302 -
Reply (to Cosinor modelling of suicides in Finland)
Hakko H, Räsänen P, Tiihonen J. 1999. Acta psychiatrica scandinavica -
Schizophrenia and seasonality of admissions: the Northern Finland 1966 birth cohort study
Räsänen P, Hakko H, Järvelin M-R, Isohanni M, Tiihonen J. 1999. Schizophrenia research -
Serum testosterone levels, mental disorders and criminal behaviour
Räsänen P, Hakko H, Visuri S, Paanila J, Kapanen P, Suomela T, Tiihonen J. 1999. Acta psychiatrica scandinavica. 99: 348-352 -
Striatal dopamine transporter density in major depression
Laasonen-Balk T, Kuikka J, Viinamäki H, Husso-Saastamoinen M, Lehtonen J, Tiihonen J. 1999. Psychopharmacology. 144: 282-285 -
Transient syncope and ECG changes associated with the concurrent administration of clozapine and diazepam
Tupala E, Niskanen L, Tiihonen J. 1999. Journal of clinical psychiatry -
Abnormal structure of human striatal dopamine re-uptake sites in habitually violent alcoholic offenders: a fractal analysis
Kuikka JT, Tiihonen J, Bergström KA, Karhu J, Räsänen P, Eronen M. 1998. Neuroscience letters. 253: 195-197 -
Change in monoamine transporter density related to clinical recovery: A case-control study
Viinamäki H, Kuikka J, Tiihonen J, Lehtonen J. 1998. Nordic journal of psychiatry. 52: 39-44 -
Fentanyl decreases beta-CIT binding to the dopamine transporter
Bergström KA, Jolkkonen J, Kuikka JT, Åkerman KK, Viinamäki H, Airaksinen O, Länsimies E, Tiihonen J. 1998. Synapse. 29: 413-415 -
Fractal analysis - a new approach in brain receptor imaging
Kuikka J, Tiihonen J. 1998. Annals of medicine. 30: 242-248 -
Helsingin yliopiston psykiatrian klinikan tutkimustoiminta vuosina 1994-1997
Virkkunen M, Tiihonen J. 1998. Sosiaalilääketieteellinen aikakauslehti. 35: 171-173 -
Imaging the structure of the striatum: a fractal approach to SPECT image interpretation
Kuikka JT, Yang J, Karhu J, Laitinen T, Tupala E, Hallikainen T, Tiihonen J. 1998. Physiological measurement. 19: 367-374 -
Increasing homicide rate in Finland accompanied by decreasing seasonality over the period 1957-95
Hakko H, Räsänen P, Tiihonen J. 1998. Social science and medicine. 47: 1695-1698 -
Iodine-123 labeled nor-beta-CIT as a potential tracer for serotonin transporter imaging in the human brain with single-photon emission tomography
Hiltunen J, Åkerman KK, Kuikka JT, Bergström KA, Halldin C, Nikula T, Räsänen P, Tiihonen J, Vauhkonen M, Karhu J, Kupila J, Länsimies E, Farde L. 1998. European journal of nuclear medicine and molecular imaging. 25: 19-23 -
Juvenile mortality, mental disturbances and criminality: a prospective study of the Northern Finland 1966 birth cohort
Räsänen P, Tiihonen J, Isohanni M, Moring J, Koiranen M. 1998. Acta psychiatrica scandinavica. 97: 5-9 -
Kuopion yliopiston oikeuspsykiatrian klinikan tutkimustoiminta vuosina 1994-1997
Tiihonen J. 1998. Sosiaalilääketieteellinen aikakauslehti. 35: 174-175 -
Mitä uutta neurofarmakologiasta?
Castrén E, Männistö PT, Tiihonen J. 1998. Duodecim. 114: 993-1001 -
Parental age gap and child sex ratio - fact or fiction?
Hakko H, Räsänen P, Järvelin M-R , Tiihonen J. 1998. International journal of epidemiology -
Pharmacokinetics and dosimetry of iodine-123 labelled PE2I in humans, a radioligand for dopamine transporter imaging
Kuikka JT, Baulieu JL, Hiltunen J, Halldin C, Bergström KA, Farde L, Emond P, Chalon S, Yu M, Nikula T, Laitinen T, Karhu J, Tupala E, Hallikainen T, Kolehmainen V, Mauclaire L, Maziere B, Tiihonen J, Guilloteau D. 1998. European journal of nuclear medicine and molecular imaging. 25: 531-534 -
Reversal of cerebral asymmetry in schizophrenia measured with magnetoencephalography
Tiihonen J, Katila H, Pekkonen E, Jääskeläinen IP, Huotilainen M, Aronen HJ, Ilmoniemi RJ, Räsänen P, Virtanen J, Salli E, Karhu J. 1998. Schizophrenia research. 30: 209-219 -
SPET psykiatrisessa tutkimuksessa
Kuikka J, Bergström K, Tiihonen J. 1998. Lääkärilehti. 53: 2301-2307 -
Schizophrenia, alcohol abuse, and violent behavior: a 26-year followup study of an unselected birth cohort
Räsänen P, Tiihonen J, Isohanni M, Rantakallio P, Lehtonen J, Moring J. 1998. Schizophrenia bulletin. 24: 437-441 -
Seasonal variation in suicide occurrence in Finland
Hakko H, Räsänen P, Tiihonen J. 1998. Acta psychiatrica scandinavica. 98: 92-97 -
Secular trends in the rates and seasonality of violent and nonviolent suicide occurrence in Finland during 1980-95
Hakko H, Räsänen P, Tiihonen J. 1998. Journal of affective disorders. 50: 49-54 -
Striatal presynaptic dopamine function in type 1 alcoholics measured with positron emission tomography
Tiihonen J, Vilkman H, Räsänen P, Ryynänen O-P, Hakko H, Bergman J, Hämäläinen T, Laakso A, Haaparanta-Solin M, Solin O, Kuoppamäki M, Syvälahti E, Hietala J. 1998. Molecular psychiatry. 4: 156-161 -
The incidence and onset-age of hospitalized bipolar affective disorder in Finland
Räsänen P, Tiihonen J, Hakko H. 1998. Journal of affective disorders. 48: 63-68 -
The metabolism of iodine-123 labelled 3-(5-cyclopropyl-1,2,4-oxadiazo-3-yl)-7-iodo-5,6-dihydro-5-methyl-6-oxo-4H-imidazo(1,5-a) (1,4)benzodiazepine (NNC 13-8241) measured in human plasma is only minor
Åkerman KK, Bergström KA, Halldin C, Lötjönen S, Yu M, Nikula T, Hiltunen J, Foged C, Kuikka JT, Tiihonen J. 1998. Human psychopharmacology: clinical and experimental. 13: 177-182 -
Benzodiazepine receptor uptake in a patient with panic disorder after citalopram treatment
Tiihonen J, Lepola U, Kuikka J. 1997. NEUROPSYCHIATRY, NEUROPSYCHOLOGY, AND BEHAVIORAL NEUROLOGY -
Cerebral benzodiazepine receptor binding and distribution in generalized anxiety disorder: a fractal analysis
Tiihonen J, Kuikka J, Räsänen P, Lepola U, Koponen H, Liuska A, Lehmusvaara A, Vainio P, Könönen M, Bergström K, Yu M, Kinnunen I, Åkerman K, Karhu J. 1997. Molecular psychiatry. 2: 463-471 -
Dopamine reuptake site densities in patients with social phobia
Tiihonen J, Kuikka J, Bergström K, Lepola U, Koponen H, Leinonen E. 1997. American journal of psychiatry. 154: 239-242 -
Fractal analysis of striatal dopamine re-uptake sites
Kuikka JT, Tiihonen J, Karhu J, Bergström KA, Räsänen P. 1997. European journal of nuclear medicine and molecular imaging. 24: 1085-1090 -
Major mental disorders and violent behaviour
Tiihonen J. Teoksessa: Edling C, Golding A(toim.) , 1997. Violence as a Public Health Issue. Proceedings of a Conference Organized by the Royal Society of Medicine and the Swedish Society of Medicine. s. 27-28. Royal Society of Medicine Press Limited -
Mental disorders and homicide: Quantitative risk assessment
Tiihonen J, Eronen M. 1997. NORDISK RETTSMEDISIN. 3: 75-78 -
Psychiatric disorders and violent behavior
Eronen M, Tiihonen J, Hakola P. 1997. International journal of psychiatry in clinical practice. 1: 179-188 -
Seasonal variation in the occurrence of homicide in Finland
Tiihonen J, Räsänen P, Hakko H. 1997. American journal of psychiatry. 154: 1711-1714 -
Single-photon emission tomography imaging of monoamine transporters in impulsive violent behaviour
Tiihonen J, Kuikka JT, Bergström KA, Karhu J, Viinamäki H, Lehtonen J, Hallikainen T, Yang J, Hakola P. 1997. European journal of nuclear medicine and molecular imaging. 24: 1253-1260 -
Specific major mental disorders and criminality: a 26-year prospective study of the 1966 northern Finland birth cohort
Tiihonen J, Isohanni M, Räsänen P, Koiranen M, Moring J. 1997. American journal of psychiatry. 154: 840-845 -
Striatal and extrastriatal imaging of dopamine D2 receptors in the living human brain with (123I)epidepride single-photon emission tomography
Kuikka JT, Åkerman KK, Hiltunen J, Bergström KA, Räsänen P, Vanninen E, Halldin C, Tiihonen J. 1997. European journal of nuclear medicine and molecular imaging. 24: 483-487 -
Characterization of C-11 or I-123 labelled beta-CIT-FP and beta-CIT-FE metabolism measured in monkey and human plasma. Identification of two labelled metabilites with HPLC
Bergström KA, Halldin C, Lundkvist C, Swan C-G, Åkerman KK, Kuikka JT, Hiltunen J, Tiihonen J, Länsimies E, Neumeyer JL, Farde L. 1996. Human psychopharmacology: clinical and experimental. 11: 483-490 -
Citalopram in the treatment of alcoholism: a double-blind placebo-controlled study
Tiihonen J, Ryynänen O-P, Kauhanen J, Hakola HPA, Salaspuro M. 1996. Pharmacopsychiatry. 29: 27-29 -
Factors associated with homicide recidivism in a 13-year sample of homicide offenders in Finland
Eronen M, Hakola P, Tiihonen J. 1996. Psychiatric services. 47: 403-406 -
Forensic psychotherapy. Book review. Cordess C, Cox M, eds. Crime, Psychodynamics and the Offender Patient
Räsänen P, Tiihonen J. 1996. The Lancet -
Initial human studies with single-photon emission tomography using iodine-123 labelled 3-(5-cyclopropyl-1,2,4-oxadiazo-3-yl)-7 -iodo-5,6-dihydro-5-methyl-6-oxo-4H-imidazo(1,5-a)(1,4) -benzodiazepine (NNC 13-8241)
Kuikka JT, Hiltunen J, Foged C, Bergström KA, Halldin C, Åkerman K, Tiihonen J, Farde L. 1996. European journal of nuclear medicine and molecular imaging. 23: 798-803 -
Low incidence of mania in northern Finland
Veijola J, Räsänen P, Isohanni M, Tiihonen J. 1996. British journal of psychiatry -
Mental disorders and homicidal behavior in Finland
Eronen M, Hakola P, Tiihonen J. 1996. Archives of general psychiatry. 53: 497-501 -
Naisten tekemät henkirikokset Suomessa 1980-94
Eronen M, Tiihonen J, Hakola P. 1996. Duodecim. 112: 1281-1286 -
Risk of homicidal behavior among discharged forensic psychiatric patients
Tiihonen J, Hakola P, Eronen M, Vartiainen H, Ryynänen O-P. 1996. Forensic science international. 79: 123-129 -
Schizophrenia and homicidal behavior
Eronen M, Tiihonen J, Hakola P. 1996. Schizophrenia bulletin. 22: 83-89 -
Serotonergic modulation of striatal D2 dopamine receptor binding in humans measured with positron emission tomography
Tiihonen J, Kuoppamäki M, Någren K, Bergman J, Eronen E, Syvälahti E, Hietala J. 1996. Psychopharmacology. 126: 277-280 -
Väkivaltainen potilas
Tiihonen J. Teoksessa: Isohanni M, Larivaara P, Winblad I(toim.) , 1996. Perusterveydenhuollon psykiatria 1. p.. s. 27-28. Duodecim -
Acute ethanol-induced changes in cerebral blood flow
Kuikka J, Tiihonen J, Hakola P, Paanila J, Airaksinen J, Eronen M, Hallikainen T. Teoksessa: Bergmann H, Sinzinger H(toim.) , 1995. Radioactive Isotopes in Clinical Medicine and Research. s. 345-350. Birkhäuser -
Altered cerebral blood flow during hysterical paresthesia
Tiihonen J, Kuikka J, Viinamäki H, Lehtonen J, Partanen J. 1995. Biological psychiatry. 37: 134-135 -
Altered striatal dopamine re-uptake site densities in habitually violent and non-violent alcoholics
Tiihonen J, Kuikka J, Bergström K, Hakola P, Karhu J, Ryynänen O-P, Föhr J. 1995. Nature medicine. 1: 654-657 -
Carbamazepine-induced changes in plasma levels of neuroleptics
Tiihonen J, Vartiainen H, Hakola P. 1995. Pharmacopsychiatry. 28: 26-28 -
Citalopram, a selective serotonin reuptake inhibitor, in the treatment of aggression in schizophrenia
Vartiainen H, Tiihonen J, Putkonen A, Koponen H, Virkkunen M, Hakola P, Lehto H. 1995. Acta psychiatrica scandinavica. 91: 348-351 -
Emootioiden neurofysiologiasta
Tiihonen J. Teoksessa: Lehtonen J, Viinamäki H, Väänänen K(toim.) , 1995. Psykiatrian vaellusvuodet. KYS:n psykiatrian klinikka 20 vuotta. s. 171-178. -
Homicidal behaviour and mental disorders
Tiihonen J, Hakola P, Eronen M. 1995. British journal of psychiatry -
Homicide and mental disorders
Tiihonen J, Hakola P. 1995. Psychiatria fennica. 26: 125-129 -
Imaging of serotonin and dopamine transporters in the living human brain
Kuikka JT, Tiihonen J, Bergström KA, Karhu J, Hartikainen P, Viinamäki H, Länsimies E, Lehtonen J, Hakola P. 1995. European journal of nuclear medicine and molecular imaging. 22: 346-350 -
Iodine-123 labelled N-(2-fluoroethyl)-2beta -carbomethoxy-3beta-(4-iodophenyl)nortropane for dopamine transporter imaging in the living human brain
Kuikka JT, Åkerman K, Bergström KA, Karhu J, Hiltunen J, Haukka J, Heikkinen J, Tiihonen J, Wang S, Neumeyer JL. 1995. European journal of nuclear medicine and molecular imaging. 22: 682-686 -
Lipophilic metabolite of [123I] beta-CIT in human plasma may obstruct quantitation of the dopamine transporter
Bergström KA, Halldin C, Kuikka JT, Swan C-G, Tiihonen J, Hiltunen J, Länsimies E, Farde L. 1995. Synapse. 19: 297-300 -
Pitfalls of SPECT studies of acute ethanol-induced changes in cerebral blood flow
Tiihonen J, Kuikka J. 1995. American journal of psychiatry -
Quantitative risk assessment of homicidal behaviour
Tiihonen J. 1995. JOURNAL OF FORENSIC PSYCHIATRY. 6: 477-485 -
Risk of homicidal behaviour among persons convicted of homicide
Tiihonen J, Hakola P, Nevalainen A, Eronen M. 1995. Forensic science international. 72: 43-48 -
The metabolite pattern of (123I)beta CIT determined with a gradient HPLC method
Bergström KA, Halldin C, Kuikka JT, Swahn C-G, Tiihonen J, Hiltunen J, Länsimies E, Farde L. 1995. Nuclear medicine and biology. 22: 971-976 -
Uusi psykoosilääke risperidoni
Tiihonen J. 1995. Duodecim -
Uusia löydöksiä skitsofreniaan liittyvistä neuroanatomisista muutoksista
Tiihonen J. 1995. SANDOZ REPORT. : 14-15 -
Uusimpia tutkimushavaintoja rikoksista syytettyjen henkilöiden oikeuspsykiatrisista mielentilatutkimuksista
Eronen M, Tiihonen J, Ylitapio J, Hakola P. 1995. Lakimies. : 538-547