JARKKO KETOLAINEN

Contact info

Research groups - UEF

• 
  Continuous Manufacturing of Tablets
• 
  3D printing of dosage forms

Publications

• Viidik, Laura; Vesala, Jemina; Laitinen, Riikka; Korhonen, Ossi; Ketolainen, Jarkko; Aruväli, Jaan; Kirsimäe, Kalle; Kogermann, Karin; Heinämäki, Jyrki; Laidmäe, Ivo; Ervasti, Tuomas. 2021. Preparation and characterization of hot-melt extruded polycaprolactone-based filaments intended for 3D-printing of tablets European journal of pharmaceutical sciences 158: 105619. 2021
• Taipale-Kovalainen, Krista; Ketolainen, Jarkko; Korhonen, Ossi; Ervasti, Tuomas. 2020. Converting a batch based high-shear granulation process to a continuous dry granulation process; a demonstration with ketoprofen tablets European journal of pharmaceutical sciences 151: 105381. 2020
• Al-Sharabi, Mohammed; Markl, Daniel; Mudley, Theona; Bawuah, Prince; Karttunen, Anssi-Pekka; Ridgway, Cathy; Gane, Patrick; Ketolainen, Jarkko; Peiponen, Kai-Erik; Rades, Thomas; Zeitler, J. Axel. 2020. Simultaneous Investigation of the Liquid Transport and Swelling Performance during Tablet Disintegration International journal of pharmaceutics 584: 119380. 2020
• Kyttä, Kaisa M; Lakio, Satu; Wikström, Håkan; Sulemanji, Anisa; Fransson, Magnus; Ketolainen, Jarkko; Tajarobi, Pirjo. 2020. Comparison between twin-screw and high-shear granulation - The effect of filler and active pharmaceutical ingredient on the granule and tablet properties Powder technology 376: 187-198. 2020
• Ervasti, Tuomas; Niinikoski, Hannes;, Mäki-Lohiluoma, Eero; Leppinen, Heidi; Ketolainen, Jarkko; Korhonen, Ossi; Lakio, Satu. 2020. The Comparison of Two Challenging Low Dose APIs in a Continuous Direct Compression Process Pharmaceutics 12 3: 279. 2020
• Karttunen, AP; Wikström, H; Tajarobi, P; Fransson, M; Sparén, A; Marucci, M; Ketolainen, J; Folestad, S; Korhonen, O; Abrahmsén-Alami, S. 2019. Comparison between integrated continuous direct compression line and batch processing - The effect of raw material properties European journal of pharmaceutical sciences 133: 40-53. 2019
• Karttunen, AP; Hörmann, TR; De Leersnyder, F; Ketolainen, J; De Beer, T; Hsiao, WK; Korhonen, O. 2019. Measurement of residence time distributions and material tracking on three continuous manufacturing lines International journal of pharmaceutics 563: 184-197. 2019
• Bawuah, Prince; Karttunen, Anssi-Pekka; Markl, Daniel; Ridgway, Cathy; Korhonen, Ossi; Gane, Patrick; Zeitler, J Axel; Ketolainen, Jarkko; Peiponen, Kai-Erik. 2018. Investigating elastic relaxation effects on the optical properties of functionalised calcium carbonate compacts using optics-based Heckel analysis INTERNATIONAL JOURNAL OF PHARMACEUTICS 544 1: 278-284. 2018
• Bawuah, Prince; Zeitler, J Axel; Ketolainen, Jarkko; Peiponen Kai-Erik. 2018. Terahertz absorption spectra of commonly used antimalarial drugs. OPTICAL REVIEW 25 3: 444-449. 2018
• Markl, Daniel; Wang, Parry; Ridgway, Cathy; Karttunen, Anssi-Pekka; Bawuah, Prince; Ketolainen, Jarkko; Gane, Patrick; Peiponen, Kai-Erik; Zeitler, J Axel. 2018. Resolving the rapid water absorption of porous functionalised calcium carbonate powder compacts by terahertz pulsed imaging. Chemical Engineering Research And Design 132: 1082-1090. 2018
• Martinetz, MC; Karttunen, AP; Sacher, S; Wahl, P; Ketolainen, J; Khinast, JG; Korhonen, O. 2018. RTD-based Material Tracking in a Fully-Continuous Dry Granulation Tableting Line INTERNATIONAL JOURNAL OF PHARMACEUTICS 547 1-2: 469-479. 2018
• Taipale-Kovalainen, Krista; Karttunen, Anssi-Pekka; Niinikoski, Hannes; Ketolainen, Jarkko; Korhonen, Ossi. 2018. The effects of unintentional and intentional process disturbances on tablet quality during long continuous manufacturing runs EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES 2019; 129: 10-20. 2018
• Markl Daniel, Bawuah Prince, Ridgway Cathy, van den Ban Sander, Goodwin Daniel J, Ketolainen Jarkko, Gane Patrick, Peiponen Kai-Erik, Zeitler J.Axel. 2017. Fast and non-destructive pore structure analysis using terahertz time-domain spectroscopy. INTERNATIONAL JOURNAL OF PHARMACEUTICS 2018; 537 1-2: 102-110. 2017
• Taipale-Kovalainen Krista, Karttunen Anssi-Pekka, Ketolainen Jarkko, Korhonen Ossi. 2017. Lubricant based determination of design space for continuously manufactured high dose paracetamol tablets. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES 2018; 115: 1-10. 2017
• Markl Daniel, Ridgway Cathy, Bawuah Prince, Gane Patrick, Ketolainen Jarkko, Peiponen Kai-Erik, Zeitler Axel. 2017. Analysis of Anisotropic Pore Structures using Terahertz Spectroscopy and Imaging. In: - (ed.) , 42nd International Conference on Infrared, Millimeter, and Terahertz Waves (IRMMW-THz), 2017. International Conference on Infrared, Millimeter, and Terahertz Waves 2017. s. -. 2017
• Ridgway Cathy, Bawuah Prince, Markl Daniel, Zeitler J Axel, Ketolainen Jarkko, Peiponen Kai-Erik, Gane Patrick. 2017. On the role of API in determining porosity, pore structure and bulk modulus of the skeletal material in pharmaceutical tablets formed with MCC as sole excipient. INTERNATIONAL JOURNAL OF PHARMACEUTICS 526 1-2: 321-331. 2017
• Lakio S, Ervasti T, Tajarobi P, Wikström H, Fransson M, Karttunen AP, Ketolainen J, Folestad S, Abrahmsén-Alami S, Korhonen O. 2017. Provoking an end-to-end continuous direct compression line with raw materials prone to segregation. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES 109: 514-524. 2017
• Chakraborty Mousumi, Ridgway Cathy, Bawuah Prince, Markl Daniel, Gane Patrick AC, Ketolainen Jarkko, Zeitler J Axel, Peiponen Kai-Erik. 2017. Optics-based compressibility parameter for pharmaceutical tablets obtained with the aid of the terahertz refractive index. INTERNATIONAL JOURNAL OF PHARMACEUTICS 525 1: 85-91. 2017
• Laitinen R, Räty J, Korhonen K, Ketolainen J, Peiponen K-E. 2017. Reflectometric monitoring of the dissolution process of thin polymeric films. INTERNATIONAL JOURNAL OF PHARMACEUTICS 523 1: 127-132. 2017
• Markl Daniel, Wang Parry, Ridgway Cathy, Karttunen Anssi-Pekka, Chakraborty Mousumi, Bawuah Prince, Pääkkönen Pertti, Gane Patrick, Ketolainen Jarkko, Peiponen Kai, Zeitler J Axel. 2017. Characterization of the Pore Structure of Functionalized Calcium Carbonate Tablets by Terahertz Time-Domain Spectroscopy and X-ray Computed Microtomography. JOURNAL OF PHARMACEUTICAL SCIENCES 106 6: 1586-1595. 2017
• Kauppinen Ari, Broekhuis Joep, Grasmeijer Niels, Tonnis Wouter, Ketolainen Jarkko, Frijlink Henderik W, Hinrichs Wouter LJ. 2017. Efficient production of solid dispersions by spray drying solutions of high solid content using a 3-fluid nozzle. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS 2018; 123: 50-58. 2017
• Korhonen Kristiina, Smolander Elina, Korhonen Ossi, Ketolainen Jarkko, Laitinen Riikka. 2017. Effect of storage on the physical stability of thin polymethacrylate-perphenazine films. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES 104: 293-301. 2017
• Bawuah Prince, Chakraborty Mousumi, Ervasti Tuomas, Zeitler J Axel, Ketolainen Jarkko, Gane Patrick A C, Peiponen Kai-Erik. 2016. A structure parameter for porous pharmaceutical tablets obtained with the aid of Wiener bounds for effective permittivity and terahertz time-delay measurement. INTERNATIONAL JOURNAL OF PHARMACEUTICS 506 1-2: 87-92. 2016
• Bawuah Prince, Ervasti Tuomas, Tan Nicholas, Zeitler J Axel, Ketolainen Jarkko, Peiponen Kai-Erik. 2016. Noninvasive porosity measurement of biconvex tablets using terahertz pulses. INTERNATIONAL JOURNAL OF PHARMACEUTICS 509 1-2: 439-443. 2016
• Bawuah Prince, Tan Nicholas, Tweneboah Samuel Nana A., Ervasti Tuomas, Zeitler J Axel, Ketolainen Jarkko, Peiponen Kai-Erik. 2016. Terahertz study on porosity and mass fraction of active pharmaceutical ingredient of pharmaceutical tablets. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS 105: 122-133. 2016
• de Matas Marcel, De Beer Thomas, Folestad Staffan, Ketolainen Jarkko, Lindén Hans, Lopes João A, Oostra Wim, Weimer Marco, Ohrngren Per, Rantanen Jukka. 2016. Strategic framework for education and training in quality by design (QbD) and process analytical technology (PAT). EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES 90: 2-7. 2016
• Korhonen Kristiina, Poikolainen Mirja, Korhonen Ossi, Ketolainen Jarkko, Laitinen Riikka. 2016. Systematic evaluation of a spraying method for preparing thin Eudragit-drug films by Design of Experiments. JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY 35: 241-251. 2016
• Kumar Ashish, Alakarjula Maija, Vanhoorne Valérie, Toiviainen Maunu, De Leersnyder Fien, Vercruysse Jurgen, Juuti Mikko, Ketolainen Jarkko, Vervaet Chris, Remon Jean Paul, Gernaey Krist V, De Beer Thomas, Nopens Ingmar. 2016. Linking granulation performance with residence time and granulation liquid distributions in twin-screw granulation: An experimental investigation. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES 90: 25-37. 2016
• Lakio Satu, Tajarobi Pirjo, Wikström Håkan, Fransson Magnus, Arnehed Johan, Ervasti Tuomas, Simonaho Simo-Pekka, Ketolainen Jarkko, Folestad Staffan, Abrahmsén-Alami Susanna. 2016. Achieving a robust drug release from extended release tablets using an integrated continuous mixing and direct compression line. INTERNATIONAL JOURNAL OF PHARMACEUTICS 511 1: 659-668. 2016
• Peters Björn-Hendrik, Staels Lotte, Rantanen Jimi, Molnár Ferdinand, De Beer Thomas, Lehto Vesa-Pekka, Ketolainen Jarkko. 2016. Effects of Cooling Rate in Microscale and Pilot Scale Freeze-Drying - Variations in Excipient Polymorphs and Protein Secondary Structure. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES 95: 72-81. 2016
• Prince Bawuah, Mousumi Chakraborty, Tuomas Ervasti, J. Axel Zeitler, Jarkko Ketolainen, Kai-Erik Peiponen. 2016. Terahertz time-domain study on selected parameters of pharmaceutical tablets using effective medium approximations. In: TUT (ed.) , Abstract. Tampere university of technology. s. N/A. 2016
• Simonaho Simo-Pekka, Ketolainen Jarkko, Ervasti Tuomas, Toiviainen Maunu, Korhonen Ossi. 2016. Continuous manufacturing of tablets with PROMIS-line - Introduction and case studies from continuous feeding, blending and tableting. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES 90: 38-46. 2016
• Chakraborty Mousumi, Bawuah Prince, Tan Nicholas, Ervasti Tuomas, Pääkkönen Pertti, Zeitler J Axel, Ketolainen Jarkko, Peiponen Kai-Erik. 2016. On the Correlation of Effective Terahertz Refractive Index and Average Surface Roughness of Pharmaceutical Tablets. Journal of Infrared, Millimeter, and Terahertz Waves First online: 14 March 2016: 1-10. 2016
• Korhonen Kristiina, Granqvist Niko, Ketolainen Jarkko, Laitinen Riikka. 2015. Monitoring of Drug Release Kinetics from Thin Polymer Films by Multi-Parametric Surface Plasmon Resonance. INTERNATIONAL JOURNAL OF PHARMACEUTICS 494 1: 531-536. 2015
• Peters Björn-Hendrik, Leskinen Jari T, Molnár Ferdinand, Ketolainen Jarkko. 2015. Impact of Microscale and Pilot-Scale Freeze-Drying on Protein Secondary Structures: Sucrose Formulations of Lysozyme and Catalase. JOURNAL OF PHARMACEUTICAL SCIENCES 104 11: 3710-3721. 2015
• Peiponen Kai-Erik, Bawuah Prince, Chakraborty Mousumi, Juuti Mikko, Zeitler J Axel, Ketolainen Jarkko. 2015. Estimation of Young's modulus of pharmaceutical tablet obtained by terahertz time-delay measurement. INTERNATIONAL JOURNAL OF PHARMACEUTICS 489 1-2: 100-105. 2015
• Järvinen Maiju A, Paavola Marko, Poutiainen Sami, Itkonen Päivi, Pasanen Ville, Uljas Katja, Leiviskä Kauko, Juuti Mikko, Ketolainen Jarkko, Järvinen Kristiina. 2015. Comparison of a continuous ring layer wet granulation process with batch high shear and fluidized bed granulation processes. POWDER TECHNOLOGY 275: 113-120. 2015
• Bawuah Prince, Ervasti Tuomas, Tan Nicholas, Ketolainen Jarkko, Zeitler J Axel, Peiponen Kai-Erik. 2015. A Quantitative study on the change of the effective refractive index of pharmaceutical tablets using terahertz-time-domain spectroscopy. In: Prince Bawuah, Kai-Eric Peiponen (ed.) , The Eleventh Finland-Japan Joint Symposium on OPTICS IN ENGINEERING (OIE2015). UEF. s. 18-19. 2015
• Kauppinen Ari, Peters Björn-Hendrik, Toiviainen Maunu, Ketolainen Jarkko. 2015. Quality control of freeze-dried protein formulations using near-infrared imaging: n/a, Inventing Tomorrow's Development and Manufacturing. 37. 2015
• Ervasti Tuomas, Aaltonen Jaakko, Ketolainen Jarkko. 2015. Theophylline-nicotinamide cocrystal formation in physical mixture during storage. INTERNATIONAL JOURNAL OF PHARMACEUTICS 486 1-2: 121-130. 2015
• Ervasti Tuomas, Simonaho Simo-Pekka, Ketolainen Jarkko, Forsberg Peter, Fransson Magnus, Wikström Håkan, Folestad Staffan, Lakio Satu, Tajarobi Pirjo, Abrahmsén-Alami Susanna. 2015. Continuous manufacturing of extended release tablets via powder mixing and direct compression. INTERNATIONAL JOURNAL OF PHARMACEUTICS 495 1: 290-301. 2015
• Bawuah Prince, Pierotic Mendia Alessandra, Silfsten Pertti, Pääkkönen Pertti, Ervasti Tuomas, Ketolainen Jarkko, Zeitler J. Axel, Peiponen Kai-Erik. 2014. Detection of porosity of pharmaceutical compacts by terahertz radiation transmission and light reflection measurement techniques. INTERNATIONAL JOURNAL OF PHARMACEUTICS Volume 465 Issues 1-2: 70-76. 2014
• Bawuah Prince, Silfsten Pertti, Ervasti Tuomas, Ketolainen Jarkko, Zeitler J. Axel, Peiponen Kai-Erik. 2014. Non-contact weight measurement of flat-faced pharmaceutical tablets using terahertz transmission pulse delay measurements. INTERNATIONAL JOURNAL OF PHARMACEUTICS 276: 16-22. 2014
• Fonteyne Margot, Wickström Henrika, Peeters Elisabeth, Vercruysse Jurgen, Ehlers Henrik, Peters Björn-Hendrik, Remon Jean P, Vervaet Chris, Ketolainen Jarkko, Sandler Niklas, Rantanen Jukka, Naelapää Kaisa, De Beer Thomas. 2014. Influence of raw material properties upon critical quality attributes of continuously produced granules and tablets. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS 87: 252-263. 2014
• Kauppinen Ari, Toiviainen Maunu, Lehtonen Marko, Järvinen Kristiina, Paaso Janne, Juuti Mikko, Ketolainen Jarkko. 2014. Validation of a multipoint near-infrared spectroscopy method for in-line moisture content analysis during freeze-drying. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS 95: 229-237. 2014
• Kauppinen Ari, Toiviainen Maunu, Lehtonen Marko, Järvinen Kristiina, Paaso Janne, Juuti Mikko, Ketolainen Jarkko. 2014. Validation of a multipoint near-infrared spectroscopy method for in-line moisture content determination during freeze-drying, Polymorfi - Celebrating 25 years of Physical Pharmacy Symposia in Finland. 27-28. 2014
• Ketolainen Jarkko, Korhonen Ossi, Laitinen Riikka, Simonaho Simo-Pekka, Molnár Ferdinand. 2014. Pharmaceutical solids and processes. DOSIS : FARMASEUTTINEN AIKAKAUSKIRJA 30 3: 195. 2014
• P. Bawuah, P. Silfsten, T. Ervasti, J. Ketolainen, A. Zeitler, K-E. Peiponen. 2014. Towards a Noninvasive Detection of the Porosity, Absolute Weight and Height of Pharmaceutical Compacts Using a Training Set of Tablets and THz Pulse Delay. In: American Association of Pharmaceutical Scientists (AAPS): Published Meeting Abstracts (ed.) , Abstract. 2014
• Pajula Katja, Wittoek Lieke, Lehto Vesa-Pekka, Ketolainen Jarkko, Korhonen Ossi. 2014. Phase separation in co-amorphous systems: in silico prediction and the experimental challenge of detection. Molecular Pharmaceutics 11: 2271-2279. 2014
• Peters Björn-Hendrik, Molnár Ferdinand, Ketolainen Jarkko. 2014. Structural attributes of model protein formulations prepared by rapid freeze-drying cycles in a microscale heating stage. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS 87: 347-356. 2014
• Trnka Hjalte, Palou Anna, Panouillot Pierre-Emanuel, Kauppinen Ari, Toiviainen Maunu, Grohganz Holger, Alcalà Manel, Juuti Mikko, Ketolainen Jarkko, Rantanen Jukka. 2014. Near-Infrared Imaging for High-Throughput Screening of Moisture-Induced Changes in Freeze-Dried Formulations. JOURNAL OF PHARMACEUTICAL SCIENCES 103: 2839-2846. 2014
• Laitinen Riikka, Honkakoski Paavo, Järvinen Kristiina, Ketolainen Jarkko. 2013. Farmasian teknologia ja biofarmasia - uusia teknologioita lääkekehitykseen monitieteellisellä yhteistyöllä: Ahonen R, Laitinen K, Lapinjoki S, Mensalo P, Ranta V-P, Ylikangas H (toim)., Muutosten vuosikymmen : Itä-Suomen yliopiston farmasian laitos 40 vuotta. Publications of the University of Eastern Finland. General Series 13. 24-30. 2013
• Vercruysse Jurgen, Toiviainen Maunu, Fonteyne Margot, Helkimo Niko, Ketolainen Jarkko, Juuti Mikko, Delaet Urbain, Van Assche Ivo, Remon Jean P, Vervaet Chris, De Beer Thomas. 2013. Visualization and understanding of the granulation liquid mixing and distribution during continuous twin screw granulation using NIR chemical imaging. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS 2014:86: 383-392. 2013
• Peiponen K-E, Silfsten P, Pajander J, Ketolainen J. 2013. Broadening of a THz pulse as a measure of the porosity of pharmaceutical tablets. INTERNATIONAL JOURNAL OF PHARMACEUTICS 447: 7-11. 2013
• Kauppinen Ari, Toiviainen Maunu, Korhonen Ossi, Aaltonen Jaakko, Järvinen Kristiina, Paaso Janne, Juuti Mikko, Ketolainen Jarkko. 2013. In-line multipoint near-infrared spectroscopy for moisture content quantification during freeze-drying. ANALYTICAL CHEMISTRY 85: 2377-2384. 2013
• Aher Suyog, Dhumal Ravindra, Mahadik Kakasaheb, Ketolainen Jarkko, Paradkar Anant. 2013. Effect of cocrystallization techniques on compressional properties of caffeine/oxalic acid 2:1 cocrystal. PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY 18: 55-60. 2013
• Kauppinen Ari, Toiviainen Maunu, Lehtonen Marko, Järvinen Kristiina, Paaso Janne, Juuti Mikko, Ketolainen Jarkko. 2013. Validation of a multipoint near-infrared spectroscopy method for in-line moisture content determination during freeze-drying: Lopes, João, Tailoring QbD & PAT Science to Pharmaceutical Industry Needs. 68. 2013
• Kauppinen Ari, Toiviainen Maunu, Aaltonen Jaakko, Korhonen Ossi, Järvinen Kristiina, Juuti Mikko, Pellinen Riikka, Ketolainen Jarkko. 2013. Micro-scale freeze-drying with Raman spectroscopy as a tool for process development. In: (ed.) , The XXIV Symposium of the Finnish Society of Physical Pharmacy. ss. 23-24. 2013
• Kauppinen Ari, Toiviainen Maunu, Aaltonen Jaakko, Korhonen Ossi, Järvinen Kristiina, Juuti Mikko, Pellinen Riikka, Ketolainen Jarkko. 2013. Microscale freeze-drying with Raman spectroscopy as a tool for process development. ANALYTICAL CHEMISTRY 85: 2109-2116. 2013
• Pajula Katja, Lehto Vesa-Pekka, Ketolainen Jarkko, Korhonen Ossi. 2012. Computational approach for fast screening of small molecular candidates to inhibit crystallization in amorphous drugs Molecular Pharmaceutics 9: 2844-2855. 2012
• Simonaho Simo-Pekka, Laitinen Riikka, Rimpiläinen Ville, Heikkinen Lasse, Vauhkonen Marko, Paaso Janne, Juuti Mikko, Ketolainen Jarkko. 2012. PROMIS Centre - innovative pharmaceutical manufacturing research and technology development in Kuopio, Finland. DOSIS : FARMASEUTTINEN AIKAKAUSKIRJA 28 3: 251-260. 2012
• Savenkov S, Piezzhev A, Oberemok Ye, Silfsten P, Ervasti T, Ketolainen J, Peiponen K-E. 2012. Characterization of porous media by means of the depolarization metrics JOURNAL OF QUANTITATIVE SPECTROSCOPY & RADIATIVE TRANSFER 113: 2503-2511. 2012
• Poutiainen Sami, Matero Sanni, Hämäläinen Tatu, Leskinen Jari, Ketolainen Jarkko, Järvinen Kristiina. 2012. Predicting granule size distribution of a fluidized bed spray granulation process by regime based PLS modeling of acoustic emission data POWDER TECHNOLOGY 228: 149-157. 2012
• Poutiainen Sami, Honkanen Marko, Becker Johanna, Nachtweide Dominique, Järvinen Kristiina, Ketolainen Jarkko. 2012. X-ray microtomography analysis of intragranular drug migration during fluidized bed and oven tray drying JOURNAL OF PHARMACEUTICAL SCIENCES 101 4: 1587-1598. 2012
• Kauppinen Ari, Toiviainen Maunu, Korhonen Ossi, Aaltonen Jaakko, Järvinen Kristiina, Juuti Mikko, Ketolainen Jarkko. 2012. In-line moisture content monitoring of the freeze dried products using multipoint NIR spectroscopy. In: (ed.) , EuPAT5. ss. 57. 2012
• Kauppinen Ari, Toiviainen Maunu, Korhonen Ossi, Aaltonen Jaakko, Järvinen Kristiina, Juuti Mikko, Ketolainen Jarkko. 2012. Freeze drying formulation and process design using Raman spectrometer equipped micro scale freeze drying stage. In: (ed.) , EuPAT5. ss. 57. 2012
• Ervasti Tuomas, Silfsten Pertti, Ketolainen Jarkko, Peiponen Kai-Erik. 2012. A study on the resolution of a terahertz spectrometer for the assessment of the porosity of pharmaceutical tablets APPLIED SPECTROSCOPY 66 3: 319-323. 2012
• Ervasti Tuomas, Rudolph Stefan, Ketolainen Jarkko. 2012. Eyecon particle imager in granule size measurements: A case study with Cellets. In: (ed.) , EuPAT5. ss. 32. 2012
• Aksu Buket, De Beer Tomas, Folestad Staffan, Ketolainen Jarkko, Lindén Hans, Lopes Joao A, de Matas Marcel, Oostra Wim, Rantanen Jukka, Weimer Marco. 2012. Strategic funding priorities in the pharmaceutical sciences allied to Quality by Design (QbD) and Process Analytical Technology (PAT) EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES 47 2: 402-405. 2012
• Leskinen Jari T, Simonaho Simo-Pekka, Hakulinen Mikko, Ketolainen Jarkko. 2012. Real-time tablet formation monitoring with ultrasound measurements in eccentric single station tablet press. INTERNATIONAL JOURNAL OF PHARMACEUTICS 2013:442 1-2: 27-34. 2012
• Rimpiläinen Ville, Poutiainen Sami, Heikkinen Lasse M, Savolainen Tuomo, Vauhkonen Marko, Ketolainen Jarkko. 2011. Electrical capacitance tomography as a monitoring tool for high-shear mixing and granulation CHEMICAL ENGINEERING SCIENCE 66 18: 4090-4100. 2011
• Turunen Elina, Mannila Janne, Laitinen Riikka, Riikonen Joakim, Lehto Vesa-Pekka, Järvinen Tomi, Ketolainen Jarkko, Järvinen Kristiina, Jarho Pekka. 2011. Fast-dissolving sublingual solid dispersion and cyclodextrin complex increase the absorption of perphenazine in rabbits. JOURNAL OF PHARMACY AND PHARMACOLOGY 63: 19 - 25. 2011
• Srinarong Parinda, Hämäläinen Suvi, Visser Marinella R, Hinrichs Wouter L J, Ketolainen Jarkko, Frijlink Henderik W. 2011. Surface-active derivative of inulin (Inutec® SP1) is a superior carrier for solid dispersions with a high drug load. JOURNAL OF PHARMACEUTICAL SCIENCES 100 6: 2333 - 2342. 2011
• Simonaho Simo-Pekka, Takala Aleksi T, Kuosmanen Marko, Ketolainen Jarkko. 2011. Ultrasound transmission measurements for tensile strength evaluation of tablets. INTERNATIONAL JOURNAL OF PHARMACEUTICS 409 1-2: 104-110. 2011
• Silfsten Pertti, Kontturi Ville, Ervasti Tuomas, Ketolainen Jarkko, Peiponen Kai-Erik. 2011. Kramers-Kronig analysis on the real refractive index of porous media in the terahertz spectral range. OPTICS LETTERS 36 5: 778-780. 2011
• Kauppinen Ari, Toiviainen Maunu, Aaltonen Jaakko, Korhonen Ossi, Järvinen Kristiina, Ketolainen Jarkko. 2011. Determination of water content in freeze dried samples using NIR spectroscopy, The XXII Symposium of the Finnish Society of Physical Pharmacy. 26. 2011
• Poutiainen Sami, Pajander Jari, Savolainen Armi, Ketolainen Jarkko, Järvinen Kristiina. 2011. Evolution of granule structure and drug content during fluidized bed granulation by X-ray microtomography and confocal Raman spectroscopy JOURNAL OF PHARMACEUTICAL SCIENCES 100 12: 5254-5269. 2011
• Ervasti Tuomas, Nippolainen Ervin, Toiviainen Maunu, Kuivalainen Kalle, Ketolainen Jarkko, Aaltonen Jaakko. 2011. An LED-based multispectral imaging system for tablet quality control. In: (ed.) , EuroPact 2011. ss. 120. 2011
• Ciurczak Emil, Ketolainen Jarkko, Laitinen Riikka, Aaltonen Jaakko, Lindén Hans. 2011. Taking PAT to the next level. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES 42: 1-2. 2011
• Nguyen Thanh T, Tran Thanh N, Willemsz Tofan A, Frijlink Henderik W, Ervasti Tuomas, Ketolainen Jarkko, van der Voort Maarschalk Kees. 2011. A density based segmentation method to determine the coordination number of a particulate system CHEMICAL ENGINEERING SCIENCE 66: 6385-6392. 2011
• Kauppinen Ari, Ruottinen Ville-Petteri, Karttunen Anssi-Pekka, Ruotsalainen Janne, Pellinen Riikka, Järvinen Kristiina, Hinkkanen Ari, Ketolainen Jarkko. 2011. Screening of excipients for stabilizing Semliki Forest virus vector during freeze-drying, 3rd PharmSciFair. 73. 2011
• Kauppinen Ari, Ruottinen Ville-Petteri, Karttunen Anssi-Pekka, Ruotsalainen Janne, Pellinen Riikka, Järvinen Kristiina, Hinkkanen Ari, Ketolainen Jarkko. 2011. Screening of excipients for stabilizing Semliki Forest virus vector during freeze-drying. In: (ed.) , 5th FinPharmaNet. ss. 19-20. 2011
• Laitinen R, Suihko E, Bjorkqvist M, Riikonen J, Lehto V-P, Jarvinen K & Ketolainen J. 2010. Perphenazine solid dispersions for orally fast-disintegrating tablets: physical stability and formulation DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY 36 5: 601 - 613. 2010
• Tuononen H, Fukunaga K, Kuosmanen M, Ketolainen J & Peiponen K-E. 2010. Wiener bounds for complex permittivity in terahertz spectroscopy: case study of two-phase pharmaceutical tablets. APPLIED SPECTROSCOPY 64 1: 127-131. 2010
• Rimpiläinen V, Kuosmanen M, Ketolainen J, Järvinen K, Vauhkonen M & Heikkinen LM. 2010. ELECTRICAL IMPEDANCE TOMOGRAPHY FOR THREE-DIMENSIONAL DRUG RELEASE MONITORING EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES 41 2: 407-413. 2010
• Matero S, Poutiainen S, Leskinen J, Järvinen K, Ketolainen J, Poso A & Reinikainen S-P. 2010. Estimation of granule size distribution for batch fluidized bed granulation process using acoustic emission and N-way PLS. JOURNAL OF CHEMOMETRICS 24: 464-471. 2010
• Leskinen Jari, Hakulinen Mikko Antero, Kuosmanen Marko, Ketolainen Jarkko, Abrahmsén-Alami Susanna, Lappalainen Reijo. 2010. Monitoring of swelling of hydrophilic polymer matrix tablets by ultrasound techniques. INTERNATIONAL JOURNAL OF PHARMACEUTICS 404 1-2: 142-147. 2010
• Leskinen J, Okkonen M, Toiviainen M, Poutiainen S, Tenhunen M, Teppola P, Lappalainen R, Ketolainen J, Järvinen K.. 2010. Labscale fluidized bed granulator instrumented with non-invasive process monitoring devices. CHEMICAL ENGINEERING JOURNAL 164 2-3: 268-274. 2010
• Rimpiläinen V, Poutiainen S, Heikkinen LM, Savolainen T, Vauhkonen M & Ketolainen J. 2010. MONITORING OF HIGH-SHEAR MIXING AND GRANULATION WITH CAPACITIVE MEASUREMENTS AND TOMOGRAPHY: Liu S, Takei M & Wang M, 6th World Congress on Industrial Process Tomography. 44-51. 2010
• Laitinen R, Lahtinen J, Silfsten P, Vartiainen E, Jarho P & Ketolainen J. 2010. An optical method for continuous monitoring of the dissolution rate of pharmaceutical powders. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS 52: 181 - 189. 2010
• Ervin Nippolainen, Tuomas Ervasti, Laure Fauch, Serguei V. Miridonov, Jarkko Ketolainen, Alexei A. Kamshilin. 2010. Fast noncontact measurements of tablet dye concentration. OPTICS EXPRESS: THE INTERNATIONAL ELECTRONIC JOURNAL OF OPTICS 18 15: 15634. 2010
• Kauppinen Ari, Reinisalo Mika, Pellinen Riikka, Korhonen Ossi, Järvinen Kristiina, Ketolainen Jarkko. 2010. Effect of freeze-drying conditions on transfection efficiency of cationic polymer DNA complexes. In: (ed.) , The XXI Symposium of the Finnish Society of Physical Pharmacy. ss. 50. 2010
• E. Nippolainen, T. Ervasti, J. Ketolainen, A. A. Kamshilin. 2010. Measuring tablet porosity using multispectral imaging system. OPTICAL REVIEW 17 3: 323-326. 2010
• Ervasti Tuomas, Ketolainen Jarkko, Aaltonen Jaakko. 2010. Spontaneous formation of theophylline-nicotinamide cocrystals. In: (ed.) , Scientia Pharmaceutica. ss. 622. 2010
• Pajula K, Taskinen M, Lehto V-P, Ketolainen J & Korhonen O. 2010. Predicting the formation and stability of amorphous small molecule binary mixtures from computationally determined Flory-Huggins interaction parameter and phase diagram. Molecular Pharmaceutics 7 3: 795-804. 2010
• Kauppinen Ari, Pellinen Riika, Karjalainen Mikko, Korhonen Ossi, Aaltonen Jaakko, Heikkilä Katri, Järvinen Kristiina, Nokelainen Minna, Ketolainen Jarkko. 2010. Design of freeze drying process for an adenovirus vector. In: (ed.) , EuPAT4. ss. 29. 2010
• Jari Leskinen, Simo-Pekka Simonaho, Mikko Antero Hakulinen, Jarkko Ketolainen. 2010. In-line ultrasound measurement system for detecting tablet integrity. INTERNATIONAL JOURNAL OF PHARMACEUTICS 400 1-2: 104-113. 2010
• Kauppinen Ari, Pellinen Riikka, Karjalainen Mikko, Korhonen Ossi, Aaltonen Jaakko, Heikkilä Katri, Järvinen Kristiina, Nokelainen Minna, Ketolainen Jarkko. 2010. Designing of freeze drying cycle for an adenovirus vector, AAPS National Biotechnology Conference. 102-103. 2010
• Laitinen R, Suihko E, Toukola K, Björkqvist M, Riikonen J, Lehto V-P, Järvinen K, Ketolainen J. 2009. Intraorally fast-dissolving particles of a poorly soluble drug: Preparation and in vitro characterization. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS 71: 271-281. 2009
• Matero S, Poutiainen S, Leskinen J, Reinikainen S-P, Ketolainen J, Järvinen K, Poso A. 2009. Monitoring the wetting phase of fluidized bed granulation process using multi-way methods: The separation of successful from unsuccessful batches CHEMOMETRICS AND INTELLIGENT LABORATORY SYSTEMS 96: 88-93. 2009
• Rimpiläinen V, Heikkinen LM, Kuosmanen M, Lehikoinen A, Voutilainen A, Vauhkonen M, Ketolainen J. 2009. An electrical impedance tomography-based approach to monitor in vitro sodium chloride dissolution from pharmaceutical tablets. REVIEW OF SCIENTIFIC INSTRUMENTS 80 103706. 2009
• Pajander J, Korhonen O, Laamanen M, Ryynänen E-L, Grimsey I, Van Veen B, Ketolainen J. 2009. Effect of formulation parameters and drug-polymer interactions on drug release from starch acetate matrix tablets. JOURNAL OF PHARMACEUTICAL SCIENCES 98 10: 3676-3690. 2009
• Paakkunainen M, Matero S, Ketolainen J, Lahtela-Kakkonen M, Poso A, Reinikainen S-P. 2009. Uncertainty in dissolution test of drug release. CHEMOMETRICS AND INTELLIGENT LABORATORY SYSTEMS 97: 82-90. 2009
• Matero S, Poutiainen S, Leskinen J, Järvinen K, Ketolainen J, Reinikainen S-P, Hakulinen M, Lappalainen R, Poso A. 2009. The feasibility of using acoustic emissions for monitoring of fluidized bed granulation. CHEMOMETRICS AND INTELLIGENT LABORATORY SYSTEMS 97: 75-81. 2009
• Kauppinen Ari, Reinisalo Mika, Pellinen Riikka, Gieseler Henning, Schneid Stefan, Rutzinger Susanne, Beirowski Jakob, Korhonen Ossi, Järvinen Kristiina, Ketolainen Jarkko. 2009. Determining the critical properties of formulations for freeze drying by DSC and FDM, 4th FinPharmaNet. 1. 2009
• Juuti M, Tuononen H, Prykäri T, Kontturi V, Kuosmanen M, Alarousu E, Ketolainen J, Myllylä R, Peiponen K-E. 2009. Optical and terahertz measurement techniques for flat-faced pharmaceutical tablets: a case study of gloss, surface roughness and bulk properties of starch acetate tablets MEASUREMENT SCIENCE AND TECHNOLOGY 20: [9 pp]. 2009
• Juuti M, Tuononen H, Prykari T, Kontturi V, Kuosmanen M, Alarousu E, Ketolainen J, Myllyla R, Peiponen KE. 2009. Optical and terahertz measurement techniques for flat-faced pharmaceutical tablets: a case study of gloss, surface roughness and bulk properties of starch acetate tablets. Measurement Science & Technology 20 1: Article Number: 015301. 2009
• Hakulinen MA, Pajander J, Leskinen J, Ketolainen J, van Veen B, Niinimäki K, Pirskanen K, Poso A, Lappalainen R. 2008. Ultrasound transmission technique as a potential tool for physical evaluation of monolithic matrix tablets. AAPS PHARMSCITECH [ONLINE: HTTP://WWW.AAPSPHARMSCITECH.ORG/] 9 1: 267-273. 2008
• Leskinen J, Hakulinen A, Ketolainen J, Abrahamsen-Alami S, Kuosmanen M and Lappalainen R.. 2008. Dissolution monitoring of hydrophilic matrix tablets by using frequency information of ultrasound echo, Abstracts: 19th Helsinki Drug Research 2008. S26. 2008
• Matero S, Poutiainen S, Leskinen J, Hakulinen M, Lahtela-Kakkonen M, Ketolainen J, Lappalainen R, Järvinen K & Poso A. 2008. Determination of batch-to-batch variation for fluidized bed granulation, Eur J Pharm Sci Vol 34 (1 Suppl 1). Abstracts: 19th Helsinki Drug Research June 9-11. S31. 2008
• Matero S, Reinikainen S-P, Lahtela-Kakkonen M, Korhonen O, Ketolainen J, Poso A. 2008. Estimation of drug release profiles of a heterogeneous set of drugs from a hydrophobic matrix tablet using molecular descriptors JOURNAL OF CHEMOMETRICS 22: 653-660. 2008
• Pajander J, Soikkeli A, Korhonen O, Forbes RT, Ketolainen J. 2008. Drug release phenomena within a hydrophobic starch acetate matrix: FTIR mapping of tablets after in vitro dissolution testing. JOURNAL OF PHARMACEUTICAL SCIENCES 97 8: 3367-3378. 2008
• Nurmi T, Kangasmäki J, Ketolainen J. 2007. Teollisen lääkkeenvalmistuksen opetusta lähes aidossa ympäristössä. Kuopion yliopiston teollisen lääkkeenvalmistuksen kurssi rantautui Sotilasapteekin Viitasaaren toimintayksikköön. DOSIS : FARMASEUTTINEN AIKAKAUSKIRJA 23 1: 53-56. 2007
• Matero S, Pajander J, Soikkeli A-M, Reinikainen S-P, Lahtela-Kakkonen M, Korhonen O, Ketolainen J, Poso A. 2007. Predicting the drug concentration in starch acetate matrix tablets from ATR-FTIR spectra using multi-way methods ANALYTICA CHIMICA ACTA (AMSTERDAM) 595: 190-197. 2007
• Mäki R, Suihko E, Rost S, Heiskanen M, Murtomaa M, Lehto V-P, Ketolainen J. 2007. Modifying drug release and tablet properties of starch acetate tablets by dry powder agglomeration. JOURNAL OF PHARMACEUTICAL SCIENCES 96 2: 438-447. 2007
• Juuti M, van Veen B, Peiponen K-E, Ketolainen J, Kalima V, Silvennoinen R, Pakkanen TT. 2006. Local and average gloss from flat-faced sodium chloride tablets. AAPS PHARMSCITECH [ONLINE: HTTP://WWW.AAPSPHARMSCITECH.ORG/] 7 1: Article 7. 2006
• M. Juuti;B. van Veen;K.-E. Peiponen;J. Ketolainen;V. Kalima;R. Silvennoinen and T.T. Pakkanen. 2006. Local and average gloss from flat-faced sodium chloride tablets. AAPS PharmSciTech 7 1: Article 7. 2006
• Matero S, Lahtela-Kakkonen M, Korhonen O, Ketolainen J, Lappalainen R, Poso A. 2006. Chemical space of orally active compounds. CHEMOMETRICS AND INTELLIGENT LABORATORY SYSTEMS 84: 134-141. 2006
• Mäki R, Suihko E, Korhonen O, Pitkänen H, Niemi R, Lehtonen M, Ketolainen J. 2006. Controlled release of saccharides from matrix tablets. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS 62: 163-170. 2006
• Pajander J, van Veen B, Korhonen O, Lappalainen R, Ketolainen J. 2006. Liquid boundary movements in cylindrical and convex hydrophobic matrix tablets: effects on tablet cracking and drug release. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS 64: 167-172. 2006
• van Veen B , Pajander J, Zuurman K, Lappalainen R, Poso A, Frijlink HW, Ketolainen J. 2005. The effect of powder blend and tablet structure on drug release mechanisms of hydrophobic starch acetate matrix tablets. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS 61: 149-157. 2005
• Suihko E, Forbes RT, Korhonen O, Ketolainen J, Paronen P, Gynther J, Poso A. 2005. Prediction of contact angle for pharmaceutical solids from their molecular structure. JOURNAL OF PHARMACEUTICAL SCIENCES 94 4: 745-758. 2005
• Korhonen O, Matero S, Poso A, Ketolainen J. 2005. Partial least square projections to latent structures analysis (PLS) in evaluating and predicting drug release from starch acetate matrix tablets JOURNAL OF PHARMACEUTICAL SCIENCES 94 12: 2716-2730. 2005
• Korhonen O, Kanerva H, Vidgren M, Urtti A, Ketolainen J. 2004. Evaluation of novel starch acetate-diltiazem controlled release tablets in healthy human volunteers. JOURNAL OF CONTROLLED RELEASE 95: 515-520. 2004
• Pohja S, Suihko E, Vidgren M, Paronen P, Ketolainen J. 2004. Starch acetate as a tablet matrix for sustained drug release JOURNAL OF CONTROLLED RELEASE 94: 293-302. 2004
• Tarvainen M, Peltonen S, Mikkonen H, Elovaara M, Tuunainen M, Paronen P, Ketolainen J, Sutinen R. 2004. Aqueous starch acetate dispersion as a novel coating material for controlled release products JOURNAL OF CONTROLLED RELEASE 96: 179-191. 2004
• Korhonen O, Pohja S, Peltonen S, Suihko E, Vidgren M, Paronen P, Ketolainen J. 2002. Effects of physical properties for starch acetate powders on tableting [online]. AAPS PHARMSCITECH [ONLINE: HTTP://WWW.AAPSPHARMSCITECH.ORG/] 3 4: [21.2.2003]. 2002
• Suihko E, Korhonen O, Järvinen T, Ketolainen J, Jarho P, Laine E, Paronen P. 2001. Complexation with tolbutamide modifies the physicochemical and tableting properties of hydroxypropyl-beta-cyclodextrin. INTERNATIONAL JOURNAL OF PHARMACEUTICS 215: 137-145. 2001
• Suihko E, Lehto V-P, Ketolainen J, Laine E, Paronen P. 2001. Dynamic solid-state and tableting properties of four theophylline forms. INTERNATIONAL JOURNAL OF PHARMACEUTICS 217: 225-236. 2001
• Suihko E, Poso A, Korhonen O, Gynther J, Ketolainen J, Paronen P. 2000. Deformation behaviors of tolbutamide, hydroxypropyl-beta-cyclodextrin, and their dispersions. PHARMACEUTICAL RESEARCH 17 8: 942-948. 2000
• Suihko E, Korhonen O, Järvinen T, Ketolainen J, Laine E, Paronen P. 1997. Evaluation of physical properties of tolbutamide/hydroxypropyl-ß-cyclodextrin inclusion complex. In: (ed.) , 16th Pharmaceutical Technology Conference and Exhibition. Vol. 2.. ss. 286-294. 1997
• Ketolainen J, Silvennoinen R, Peiponen K-E, Laakkonen P, Suihko E, Räsänen J, Matsuda K, Paronen P. 1997. Optical homogeneity of tablet surfaces. In: (ed.) , 16th Pharmaceutical Technology Conference and Exhibition. Vol. 1a.. ss. 624-628. 1997
• Päivärinta J, Poso A, Gynther J, Suihko E, Ketolainen J. 1997. Computational elasticity of anhydrous betalactose, 16th Pharmaceutical Technology Conference and Exhibition. Vol. 2.. 509-522. 1997
• Avila E, Suihko E, Muñoz-Ruiz A, Jimenez-Castellanos M, Justo A, Cucala J, Ketolainen J, Paronen P. 1997. Predicting preferred orientation of crystals due to tabletting from particle image analysis, 16th Pharmaceutical Technology Conference and Exhibition. Vol. 1a.. 617-623. 1997
• Raatikainen P, Silvennoinen R, Ketolainen J, Ketolainen P, Paronen P. 1996. A comparison of three- and four-point beam bending tests using double-exposure holographic interferometry, Proceedings of the 15th Pharmaceutical Technology Conference. Vol. 1a.. 356-361. 1996
• Raatikainen P, Stor-Pellinen J, Räikkönen H, Ketolainen J, Luukkala M, Paronen P. 1996. Evaluation of compressional characteristics of some excipients using ultrasonic measurement, Proceedings of the 15th Pharmaceutical Technology Conference. Vol 1a.. 351-355. 1996
• Silvennoinen R, Raatikainen P, Ketolainen J, Ketolainen P, Paronen P. 1996. Holographic evaluation of bending and integrity of pharmaceutical powder beams. INTERNATIONAL JOURNAL OF PHARMACEUTICS 131: 209-217. 1996
• Suihko E, Poso A, Ketolainen J, Gynther J, Paronen P. 1996. Partial least squares (pls) analysis in prediction of contact angles for pharmaceutical materials, Proceedings of the 15th Pharmaceutical Technology Conference. Vol. 2a.. 259-264. 1996
• Ketolainen J, Kubicár L, Bohác V, Markovic M, Paronen P. 1995. Thermophysical properties of some pharmaceutical excipients compressed in tablets. PHARMACEUTICAL RESEARCH 12 11: 1701-1707. 1995
• Ketolainen J, Oksanen M, Rantala J, Stor-Pellinen J, Luukkala M, Paronen P. 1995. Photoacoustic evaluation of elasticity and integrity of pharmaceutical tablets. INTERNATIONAL JOURNAL OF PHARMACEUTICS 125: 45-53. 1995
• Ketolainen J, Oksanen M, Rantala J, Stor-Pellinen J, Luukkala M, Paronen P. 1995. Photoacoustic investigation of tablet integrity, Proceedings of the 14th Pharmaceutical Technology Conference. 561-565. 1995
• Ketolainen J, Poso A, Viitasaari V, Gynther J, Pirttimäki J, Laine E, Paronen P. 1995. Changes in solid-state structure of cyclophosphamide monohydrate induced by mechanical treatment and storage PHARMACEUTICAL RESEARCH 12 2: 299-304. 1995
• Ketolainen J, Suihko E, Poso A, Ahlgren M, Gynther J, Paronen P. 1995. Characterization of physical properties of theophylline and its polymorphs, Proceedings of the 14th Pharmaceutical Technology Conference. Vol. 3. 109-115. 1995
• Ketolainen J. 1995. Evaluation of Changes in Physical Properties of Tablets and Tableting Materials due to Mechanical and Thermal Stress. Kuopion yliopiston julkaisuja A. Farmaseuttiset tieteet. 1995
• Raatikainen P, Silvennoinen R, Ketolainen J, Ketolainen P, Paronen P. 1995. Evaluation of elasticity and homogeneity of compacts by double-exposure holographic interferometry, Proceedings of the 14th Pharmaceutical Technology Conference. Vol. 1. 125-133. 1995
• Ketolainen J, Kubicar L, Bohac V, Markovic M, Laakkonen M, Paronen P. 1994. Evaluation of thermophysical properties of pharmaceutical tablets by heat pulse method, Proceedings of the 13th Pharmaceutical Technology Conference. 141-151. 1994
• Oksanen M, Ketolainen J, Rantala J, Stor-Pellinen J, Paronen P, Luukkala M. 1994. Pulsed photoacustic evaluation of tablet integrity: Thompson DO, Chimenti DE, Review of Progress in Quantitative Nondestructive Evaluation.Plenum Press. 449-453. 1994
• Raatikainen P, Pöntinen T, Ilkka J, Ketolainen J, Paronen P. 1994. Critical evaluation of three point bending test for measuring Young's modulus of pharmaceutical powders, Proceedings of the 13th Pharmaceutical Technology Conference. 192-203. 1994