Juha Pulkkinen

Herbivory by an outbreaking moth increases emissions of biogenic volatiles and leads to enhanced secondary organic aerosol formation capacity

Yli-Pirilä Pasi, Copolovici Lucian, Kännaste Astrid, Noe Steffen, Blande James D, Mikkonen Santtu, Klemola Tero, Pulkkinen Juha, Virtanen Annele, Laaksonen Ari, Joutsensaari Jorma, Niinemets Ülo, Holopainen Jarmo K. 2016. Environmental science and technology. 50: 11501-11510

Improved assays for xenosensor activation based on reverse transfection

Küblbeck Jenni, Anttila Teemu, Pulkkinen Juha T, Honkakoski Paavo. 2015. Toxicology in vitro. 29: 1759-1765

Synthesis and Biological Evaluation of Second-Generation Tropanol-Based Androgen Receptor Modulators

Sundén Henrik, Holland Mareike C, Poutiainen Pekka K, Jääskeläinen Tiina, Pulkkinen Juha T, Palvimo Jorma J, Olsson Roger. 2015. Journal of medicinal chemistry. 58: 1569-1574

Preclinical pharmacology of FL442, a novel nonsteroidal androgen receptor modulator

Poutiainen Pekka K, Huhtala Tuulia, Jääskeläinen Tiina, Petsalo Aleksanteri, Küblbeck Jenni, Kaikkonen Sanna, Palvimo Jorma J, Raunio Hannu, Närvänen Ale, Peräkylä Mikael, Juvonen Risto O, Honkakoski Paavo, Laatikainen Reino, Pulkkinen Juha T. 2014. Molecular and cellular endocrinology. 387: 8-18

Discovery of 5-benzyl-3-phenyl-4,5-dihydroisoxazoles and 5-benzyl-3-phenyl-1,4,2-dioxazoles as potent firefly luciferase inhibitors

Poutiainen Pekka K, Palvimo Jorma J, Hinkkanen Ari E, Valkonen Arto, Väisänen Topi K, Laatikainen Reino, Pulkkinen Juha T. 2013. Journal of medicinal chemistry. 56: 1064-1073

Firefly luciferase inhibitor-conjugated peptide quenches bioluminescence: a versatile tool for real time monitoring cellular uptake of biomolecules

Poutiainen Pekka K, Rönkkö Teemu, Hinkkanen Ari E, Palvimo Jorma J, Närvänen Ale, Turhanen Petri, Laatikainen Reino, Weisell Janne, Pulkkinen Juha T. 2013. Bioconjugate chemistry. 2014:25: 4-10

Novel non-steroidal compounds as androgen receptor modulators

Pulkkinen Juha, Poutiainen Pekka, Oravilahti Tuomas, Palvimo Jorma, Peräkylä Mikael, Laatikainen Reino, Ihalainen Tarja. 2013.

Urinary glycol ether metabolites in women and time to pregnancy: The PELAGIE cohort

Garlantézec Ronan, Warembourg Charline, Monfort Christine, Labat Laurence, Pulkkinen Juha, Bonvallot Nathalie, Multigner Luc, Chevrier Cécile, Cordier Sylvaine. 2013. Environmental health perspectives. 121: 1167-1173

Design, synthesis and biological evaluation of nonsteroidal cycloalkane[d]isoxazole-containing androgen receptor modulators

Poutiainen Pekka, Oravilahti Tuomas, Peräkylä Mikael, Palvimo Jorma, Ihalainen Janne, Laatikainen Reino, Pulkkinen Juha. 2012. Journal of medicinal chemistry. 55: 6316-6327

Exposure during pregnancy to glycol ethers and chlorinated solvents and the risk of congenital malformations

Cordier Sylvaine, Garlantézec Ronan, Labat Laurence, Rouget Florence, Monfort Christine, Bonvallot Nathalie, Roig Benoit, Pulkkinen Juha, Chevrier Cécile, Multigner Luc. 2012. Epidemiology. 23: 806-812

Molecular dynamics simulations for human CAR inverse agonists

Jyrkkärinne Johanna, Küblbeck Jenni, Pulkkinen Juha, Honkakoski Paavo, Laatikainen Reino, Poso Antti, Laitinen Tuomo. 2012. Journal of chemical information and modeling. 52: 457-464

Urinary biomarkers of exposure to glycol ethers and chlorinated solvents during pregnancy: determinants of exposure and comparison with indirect methods of exposure assessment

Ronan Garlantézec, Luc Multigner, Laurence Labat, Nathalie Bonvallot, Juha Pulkkinen, Brigitte Dananché, Christine Monfort, Florence Rouget, Sylvaine Cordier. 2011. Occupational and environmental medicine. 69: 62-70

Birch (Betula spp.) leaves adsorb and re-release volatiles specific to neighbouring plants - a mechanism for associational herbivore resistance?

Himanen SJ, Blande JD, Klemola T, Pulkkinen J, Heijari J & Holopainen JK. 2010. New phytologist. 186: 722-732

Sex hormones and their analogues in neuroimmune biology.

Berczi, I.; Laatikainen, R.; Pulkkinen, J.. 2010. Immunology, endocrine and metabolic agents in medicinal chemistry. 10: 142-181

Synthesis and biological evaluation of phenolic 4,5-dihydroisoxazoles and 3-hydroxy ketones as estrogen receptor alpha and beta agonists

Poutiainen, Pekka K.; Venäläinen, Tuomas A.; Peräkylä, Mikael; Matilainen, Juha M.; Väisänen, Sami; Honkakoski, Paavo; Laatikainen, Reino; Pulkkinen, Juha T. 2010. Bioorganic and medicinal chemistry. 18: 3437-3447

Novel 4,5-dihydroisoxazoles with estrogenic activity

Pulkkinen J, Honkakoski P, Peräkylä M, Berczi I, Laatikainen R. 2009.

Novel beta-hydroxyketones and beta-alkoxyketones with estrogenic activity

Pulkkinen J, Honkakoski P, Peräkylä M, Berczi I, Laatikainen R. 2009.

Ligand specificity of constitutive androstane receptor as probed by induced-fit drocking and mutagenesis

Repo S, Jyrkkärinne J, Pulkkinen JT, Laatikainen R, Honkakoski P, Johnson MS. 2008. Journal of medicinal chemistry. 51: 7119-7131

Synthesis and evaluation of estrogen agonism of diaryl 4,5-dihydroisoxazoles, 3-hydroxyketones, 3-methoxyketones, and 1,3-diketones: A compound set forming a 4D molecular library

Pulkkinen JT, Honkakoski P, Peräkylä M, Berczi I, Laatikainen R. 2008. Journal of medicinal chemistry. 51: 3562-3571

The influence of different nutrient levels on insect-induced plant volatiles in Bt and conventional oilseed rape plants

Ibrahim MA, Stewart-Jones A, Pulkkinen J, Poppy GM, Holopainen JK. 2008. Plant biology. 10: 97-107

Biomonitoring of 2-(2-alkoxyethoxy)ethanols by analysing urinary2-(2-alkoxyethoxy)acetic acids

Laitinen J, Pulkkinen J. 2005. Toxicology letters. : 117-126

Application of novel metallocomplexes for mimicking of cytochrome P450 analysis of product distribution for 1-hexene as a substrate

Pulkkinen J, Zachar P, Borek VA, Laatikainen R, Kral V. 2004. Journal of molecular catalysis A : chemical. 219: 21-27

Highly enantio- and diastereoselective organocatalytic domino michael-aldol reactions of beta-diketone and beta-ketosulfone nucleophiles with alfa,beta-unsaturated ketones

Pulkkinen J, Aburel PS, Halland N, Jorgensen KA. 2004. Advanced synthesis and catalysis. : 1077-1080

Propylene glycol monomethyl ether occupational exposure (PGME). 4. Analysis of 2-methoxypropionic acid in urine

Devanthéry A, Berode M, Droz P-O, Pulkkinen J. 2003. International archives of occupational and environmental health. 76: 151-155

Conformational flexibility and role of aromatic-aromatic interactions in the crystal packing of the coordination compounds of some novel quadridentate Schiff bases

Pulkkinen JT, Laatikainen R, Ahlgrén MJ, Peräkylä M, Vepsäläinen JJ. 2000. JOURNAL OF THE CHEMICAL SOCIETY. PERKIN 2. 2: 777-784

1,5-Diphenylpentane-2,4-dione and 1,5-bis (2-naphtyl)pentane-2,4-dione

Pulkkinen J, Ahlgrén MJ. 1999. Acta crystallographica section C : crystal structure communications. 55: [29.11.1999]

Characterization of a conformationally flexible system: NMR spectroscopic study of 1,5-diphenylpentane-2,4-dione

Pulkkinen JT, Laatikainen R, Vepsäläinen JJ, Ahlgrén MJ. 1999. Magnetic resonance in chemistry. 37: 119-126

Synthesis and Structural Properties of Some Novel Quadridentate Schiff Base Ligands, Their Transition Metal Complexes and Precursor 1,5-Diaryl-2,4-Pentanediones

Pulkkinen J. 1999. Kuopion yliopiston julkaisuja C. Luonnontieteet ja ympäristötieteet

3-unsubstituted 1,5-Diaryl-2,4-pentanediones and -4-methoxy-2- pentanones: Synthesis via corresponding 3-hydroxy ketones generated from 2-isoxazolines

Pulkkinen JT, Vepsäläinen JJ. 1996. Journal of organic chemistry. 61: 8604-8609

A general route to 3-unsubstituted 1,5-diaryl-2,4-pentanediones and -4-methoxy-2-pentanones

Pulkkinen, Juha; Vepsäläinen, Jouko; Laatikainen, Reino. 1994. Tetrahedron letters. 35: 9749-9750

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Publications

Herbivory by an outbreaking moth increases emissions of biogenic volatiles and leads to enhanced secondary organic aerosol formation capacity

Improved assays for xenosensor activation based on reverse transfection

Synthesis and Biological Evaluation of Second-Generation Tropanol-Based Androgen Receptor Modulators

Preclinical pharmacology of FL442, a novel nonsteroidal androgen receptor modulator

Discovery of 5-benzyl-3-phenyl-4,5-dihydroisoxazoles and 5-benzyl-3-phenyl-1,4,2-dioxazoles as potent firefly luciferase inhibitors

Firefly luciferase inhibitor-conjugated peptide quenches bioluminescence: a versatile tool for real time monitoring cellular uptake of biomolecules

Novel non-steroidal compounds as androgen receptor modulators

Urinary glycol ether metabolites in women and time to pregnancy: The PELAGIE cohort

Design, synthesis and biological evaluation of nonsteroidal cycloalkane[d]isoxazole-containing androgen receptor modulators

Exposure during pregnancy to glycol ethers and chlorinated solvents and the risk of congenital malformations

Molecular dynamics simulations for human CAR inverse agonists

Urinary biomarkers of exposure to glycol ethers and chlorinated solvents during pregnancy: determinants of exposure and comparison with indirect methods of exposure assessment

Birch (Betula spp.) leaves adsorb and re-release volatiles specific to neighbouring plants - a mechanism for associational herbivore resistance?

Sex hormones and their analogues in neuroimmune biology.

Synthesis and biological evaluation of phenolic 4,5-dihydroisoxazoles and 3-hydroxy ketones as estrogen receptor alpha and beta agonists

Novel 4,5-dihydroisoxazoles with estrogenic activity

Novel beta-hydroxyketones and beta-alkoxyketones with estrogenic activity

Ligand specificity of constitutive androstane receptor as probed by induced-fit drocking and mutagenesis

Synthesis and evaluation of estrogen agonism of diaryl 4,5-dihydroisoxazoles, 3-hydroxyketones, 3-methoxyketones, and 1,3-diketones: A compound set forming a 4D molecular library

The influence of different nutrient levels on insect-induced plant volatiles in Bt and conventional oilseed rape plants

Biomonitoring of 2-(2-alkoxyethoxy)ethanols by analysing urinary2-(2-alkoxyethoxy)acetic acids

Application of novel metallocomplexes for mimicking of cytochrome P450 analysis of product distribution for 1-hexene as a substrate

Highly enantio- and diastereoselective organocatalytic domino michael-aldol reactions of beta-diketone and beta-ketosulfone nucleophiles with alfa,beta-unsaturated ketones

Propylene glycol monomethyl ether occupational exposure (PGME). 4. Analysis of 2-methoxypropionic acid in urine

Conformational flexibility and role of aromatic-aromatic interactions in the crystal packing of the coordination compounds of some novel quadridentate Schiff bases

1,5-Diphenylpentane-2,4-dione and 1,5-bis (2-naphtyl)pentane-2,4-dione

Characterization of a conformationally flexible system: NMR spectroscopic study of 1,5-diphenylpentane-2,4-dione

Synthesis and Structural Properties of Some Novel Quadridentate Schiff Base Ligands, Their Transition Metal Complexes and Precursor 1,5-Diaryl-2,4-Pentanediones

3-unsubstituted 1,5-Diaryl-2,4-pentanediones and -4-methoxy-2- pentanones: Synthesis via corresponding 3-hydroxy ketones generated from 2-isoxazolines

A general route to 3-unsubstituted 1,5-diaryl-2,4-pentanediones and -4-methoxy-2-pentanones