Jukka Jolkkonen
Research Director
Institute of Biomedicine, School of Medicine, Faculty of Health Sciences
[email protected] | +358 40 355 2519
Major Research Interests
Mechanisms underlying brain repair following stroke and development of restorative therapies to enhance functional recovery.
Research Methods
Experimental stroke models, sensorimotor and cognitive behavioral tests, histology, electron microscopy, stereological counting methods and different imaging modalities (SPECT, MRI).
Research groups
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- MSc (Biochemistry), University of Kuopio, 1983
- PhD, University of Kuopio (Clinical Biochemistry), 1991
- Adjunct Professor (Docent) in Neurobiology, University of Kuopio, 1994
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- Postdoctoral Fellow, Pharmacology Group, University of London, UK, 1991-93
- Senior Scientist, Department of Neurology, University of Kuopio, 1994-2005
- Reasearch Director, University of Eastern Finland, 2005-
- Visiting Professor, China Medical University, China, 2012-
Publications
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ciRS-7 and miR-7 regulate ischemia-induced neuronal death via glutamatergic signaling
Scoyni, Flavia; Sitnikova, Valeriia; Giudice, Luca; Korhonen, Paula; Trevisan, Davide M; Hernandez de Sande, Ana; Gomez-Budia, Mireia; Giniatullina, Raisa; Ugidos, Irene F; Dhungana, Hiramani; Pistono, Cristiana; Korvenlaita, Nea; Välimäki, Nelli-Noora; Kangas, Salla M; Hiltunen, Anniina E; Gribchenko, Emma; Kaikkonen-Määttä, Minna U; Koistinaho, Jari; Ylä-Herttuala, Seppo; Hinttala, Reetta; Venø, Morten T; Su, Junyi; Stoffel, Markus; Schaefer, Anne; Rajewsky, Nikolaus; Kjems, Jørgen; LaPierre, . 2024. Cell reports. 43: A1 Journal article (refereed), original research -
Blockade of CCR5 suppresses paclitaxel-induced peripheral neuropathic pain caused by increased deoxycholic acid
Zhong, Shanshan; Liu, Fangxi; Giniatullin, Rashid; Jolkkonen, Jukka; Li, Yong; Zhou, Zhike; Lin, Xinyu; Liu, Chang; Zhang, Xiuchun; Liu, Zhouyang; Lv, Cheng; Guo, Qianqian; Zhao, Chuansheng. 2023. Cell reports. 42: . 113386 A1 Journal article (refereed), original research -
Dynamic release of neuronal extracellular vesicles containing miR‐21a‐5p is induced by hypoxia
Korvenlaita, Nea; Gómez‐Budia, Mireia; Scoyni, Flavia; Pistono, Cristiana; Giudice, Luca; Eamen, Shaila; Loppi, Sanna; de Sande, Ana Hernández; Huremagic, Benjamin; Bouvy‐Liivrand, Maria; Heinäniemi, Merja; Kaikkonen, Minna U.; Cheng, Lesley; Hill, Andrew F.; Kanninen, Katja M.; Jenster, Guido W.; van Royen, Martin E.; Ramiro, Laura; Montaner, Joan; Batkova, Tereza; Mikulik, Robert; Giugno, Rosalba; Jolkkonen, Jukka; Korhonen, Paula; Malm, Tarja. 2023. Journal of extracellular vesicles. 12: A1 Journal article (refereed), original research -
Editorial: Common and distinct mechanisms of migraine and stroke
Giniatullin, Rashid; Khazipov, Roustem; van den Maagdenberg, Arn M. J. M.; Jolkkonen, Jukka. 2023. Frontiers in cellular neuroscience. 17: . 1171836 B1 Non-refereed journal articles -
Join us on an amazing journey towards next‐generation treatments for CNS disorders: Launch of Neuroprotection, a new high‐quality journal in translational neuroscience
Ji, Xunming; Walczak, Piotr; van Beusekom, Heleen MM.; Casas, Ana I.; Clarkson, Andrew; Farr, Tracy; Jolkkonen, Jukka; Liang, Yajie; Modo, Michel M.; Rosado‐de‐Castro, Paulo H; Ruscher, Karsten; Wang, Yan‐Jiang; Wu, Haitao; Zille, Marietta; Li, Shen; Boltze, Johannes. 2023. Neuroprotection. 1: 5-8 B1 Non-refereed journal articles -
Activation of Meningeal Afferents Relevant to Trigeminal Headache Pain after Photothrombotic Stroke Lesion: A Pilot Study in Mice
Krivoshein, Georgii; Bakreen, Abdulhameed; van den Maagdenberg, Arn MJM; Malm, Tarja; Giniatullin, Rashid; Jolkkonen, Jukka. 2022. International journal of molecular sciences. 23: A1 Journal article (refereed), original research -
Astrocyte Progenitors Derived From Patients With Alzheimer Disease Do Not Impair Stroke Recovery in Mice
Välimäki, Nelli-Noora; Bakreen, Abdulhameed; Häkli, Sara; Dhungana, Hiramani; Keuters, Meike H; Dunlop, Yannick; Koskuvi, Marja; Keksa-Goldsteine, Velta; Oksanen, Minna; Jäntti, Henna; Lehtonen, Šárka; Malm, Tarja; Koistinaho, Jari; Jolkkonen, Jukka. 2022. Stroke. 53: 3192-3201 A1 Journal article (refereed), original research -
Impact of drug treatment and drug interactions in post-stroke epilepsy
Zhao, Lanqing; Li, Jinwei; Kälviäinen, Reetta; Jolkkonen, Jukka; Zhao, Chuansheng. 2022. Pharmacology and therapeutics. 233: A2 Review article, Literature review, Systematic review -
Long-term modification of gut microbiota by broad-spectrum antibiotics improves stroke outcome in rats
Liu, Chang; Cheng, Xi; Zhong, Shanshan; Liu, Zhouyang; Liu, Fangxi; Lin, Xinyu; Zhao, Yinan; Guan, Meiting; Xiao, Ting; Jolkkonen, Jukka; Wang, Ying; Zhao, Chuansheng. 2022. Stroke and vascular neurology. 7: 381-389 A1 Journal article (refereed), original research -
Perioperative stroke: A perspective on challenges and opportunities for experimental treatment and diagnostic strategies
Jin, Xia; Li, Peiying; Michalski, Dominik; Li, Shen; Zhang, Yueman; Jolkkonen, Jukka; Cui, Lili; Didwischus, Nadine; Xuan, Wei; Boltze, Johannes. 2022. Cns neuroscience and therapeutics. 28: 497-509 A2 Review article, Literature review, Systematic review