Jyrki Virtanen
Research Director
Nutrition researcher
Institute of Public Health and Clinical Nutrition, School of Medicine, Faculty of Health Sciences
[email protected] | +358 40 355 2957
I am a nutrition researcher, an adjunct professor of nutritional epidemiology and a licensed nutritionist. My main topics of interest include the role of dietary factors in development of chronic diseases, mainly cardiovascular diseases, type 2 diabetes and memory disorders. The study methods include both observational cohort studies and clinical trials.
Research groups
Projects
Publications
158/158 items-
Adherence to a healthy Nordic diet is associated with a lower prevalence of depressive symptoms
Roponen, Johanna; Virtanen, Jyrki K; Partonen, Timo; Absetz, Pilvikki; Hantunen, Sari; Tuomainen, Tomi Pekka; Nuutinen, Outi; Tolmunen, Tommi; Ruusunen, Anu, 2025, British journal of nutrition, 134, 1, 79-85. A1 Journal article (refereed), original research -
Associations of serum n-6 polyunsaturated fatty acid concentrations with heart rate at rest, during and after exercise in men
Esmaili, Haleh; Tajik, Behnam; Tuomainen, Tomi-Pekka; Kurl, Sudhir; Salonen, Jukka T; Virtanen, Jyrki K, 2025, Nutrition metabolism and cardiovascular diseases, 35, 7, 103873. A1 Journal article (refereed), original research -
Concentrations of the serum long-chain omega-3 polyunsaturated fatty acids and hair mercury in men in different apolipoprotein E phenotypes
Fagerholm, Unna; Virtanen, Heli EK; Tuomainen, Tomi-Pekka; Salonen, Jukka T; Virtanen, Jyrki K, 2025, Biometals, 38, 3, 807-816. A1 Journal article (refereed), original research -
Serum copper, zinc and selenium and their ratios as predictors of pneumonia death risk in men: the Kuopio Ischaemic Heart Disease Risk Factor Study
Laine, Jaakko T; Tuomainen, Tomi Pekka; Salonen, Jukka T; Virtanen, Jyrki K, 2025, Infection, [Epub ahead of print 10 July 2025], 1-8. A1 Journal article (refereed), original research -
The effect of vitamin D3 supplementation on the incidence of diagnosed dementia among healthy older adults – the Finnish Vitamin D Trial
Lönnroos, Eija; Ylilauri, Maija; Lamberg-Allardt, Christel; Manson, Jo Ann E; Nurmi, Tarja; Uusitupa, Matti; Voutilainen, Ari; Hantunen, Sari; Tuomainen, Tomi-Pekka; Virtanen, Jyrki K, 2025, Journals of gerontology series a: biological sciences and medical sciences, 80, 7, glaf077. A1 Journal article (refereed), original research -
Associations of the serum n-6 PUFA concentrations with exercise-induced myocardial ischaemia in middle-aged and older men
Esmaili, Haleh; Tajik, Behnam; Tuomainen, Tomi-Pekka; Kurl, Sudhir; Salonen, Jukka T; Virtanen, Jyrki K, 2024, British journal of nutrition, 132, 11, 1522-1529. A1 Journal article (refereed), original research -
Consensus Statement on Vitamin D Status Assessment and Supplementation: Whys, Whens, and Hows
Giustina, Andrea; Bilezikian, John P; Adler, Robert A; Banfi, Giuseppe; Bikle, Daniel D; Binkley, Neil C; Bollerslev, Jens; Bouillon, Roger; Brandi, Maria Luisa; Casanueva, Felipe F; di Filippo, Luigi; Donini, Lorenzo M; Ebeling, Peter R; Fuleihan, Ghada El-Hajj; Fassio, Angelo; Frara, Stefano; Jones, Glenville; Marcocci, Claudio; Martineau, Adrian R; Minisola, Salvatore; Napoli, Nicola; Procopio, Massimo; Rizzoli, Rene; Schafer, Anne L; Sempos, Christopher T; Ulivieri, Fabio Massimo; Virtanen,, 2024, Endocrine reviews, 45, 5, 624-654. A2 Review article, Literature review, Systematic review -
Eggs – a scoping review for Nordic Nutrition Recommendations 2023
Virtanen, Jyrki K; Larsson, Susanna C, 2024, Food and nutrition research, 68, 1-19. A2 Review article, Literature review, Systematic review -
General and abdominal adiposity and hypertension in eight world regions: a pooled analysis of 837 population-based studies with 7·5 million participants
NCD Risk Factor Collaboration (NCD-RisC), 2024, The Lancet, 404, 10455, 851-863. A1 Journal article (refereed), original research -
In vivo vitamin D targets reveal the upregulation of focal adhesion-related genes in primary immune cells of healthy individuals
Ghosh Dastidar, Ranjini; Jaroslawska, Julia; Malinen, Marjo; Tuomainen, Tomi Pekka; Virtanen, Jyrki K; Bendik, Igor; Carlberg, Carsten, 2024, Scientific reports, 14, 1, 17552. A1 Journal article (refereed), original research -
Meat and meat products – a scoping review for Nordic Nutrition Recommendations 2023
Meinilä, Jelena; Virtanen, Jyrki K, 2024, Food and nutrition research, 68, 10538. A2 Review article, Literature review, Systematic review -
Omega-3 Blood Levels and Stroke Risk: A Pooled and Harmonized Analysis of 183 291 Participants From 29 Prospective Studies
O’Keefe, James H.; Tintle, Nathan L.; Harris, William S.; O’Keefe, Evan L.; Sala-Vila, Aleix; Attia, John; Garg, G. Manohar; Hure, Alexis; Bork, Christian Sørensen; Schmidt, Erik Berg; Venø, Stine Krogh; Chien, Kuo-Liong; Chen, Yun-Yu (Amelia); Egert, Sarah; Feldreich, Tobias Rudholm; Ärnlöv, Johan; Lind, Lars; Forouhi, Nita G.; Geleijnse, Johanna M.; Pertiwi, Kamalita; Imamura, Fumiaki; de Mello Laaksonen, Vanessa; Uusitupa, W. Matti; Tuomilehto, Jaakko; Laakso, Markku; Lankinen, Maria Anneli;, 2024, Stroke, 55, 1, 50-58. A1 Journal article (refereed), original research -
Role of Polyunsaturated Fat in Modifying Cardiovascular Risk Associated With Family History of Cardiovascular Disease: Pooled De Novo Results From 15 Observational Studies
Laguzzi, F.; Åkesson, A.; Marklund, M.; Qian, F.; Gigante, B.; Bartz, T.M.; Bassett, J.K.; Birukov, A.; Campos, H.; Hirakawa, Y.; Imamura, F.; Jäger, S.; Lankinen, M.; Murphy, R.A.; Senn, M.; Tanaka, T.; Tintle, N.; Virtanen, J.K.; Yamagishi, K.; Allison, M.; Brouwer, I.A.; De Faire, U.; Eiriksdottir, G.; Ferrucci, L.; Forouhi, N.G.; Geleijnse, J.M.; Hodge, A.M; Kimura, H.; Laakso, M.; Risérus, U.; van Westing, A.C.; Bandinelli, S.; Baylin, A.; Giles, G.G.; Gudnason, V.; Iso, H.; Lemaitre, R.N.;, 2024, Circulation, 149, 4, 305-316. A1 Journal article (refereed), original research -
The effect of vitamin D3 supplementation on the incidence of type 2 diabetes in healthy older adults not at high risk for diabetes (FIND): a randomised controlled trial
Virtanen, Jyrki K; Hantunen, Sari; Kallio, Niko; Lamberg-Allardt, Christel; Manson, JoAnn E.; Nurmi, Tarja; Pihlajamäki, Jussi; Uusitupa, Matti; Voutilainen, Ari; Tuomainen, Tomi-Pekka, 2024, Diabetologia, [Published: 02 December 2024], 1-12. A1 Journal article (refereed), original research -
Worldwide trends in underweight and obesity from 1990 to 2022: a pooled analysis of 3663 population-representative studies with 222 million children, adolescents, and adults
NCD Risk Factor Collaboration (NCD-RisC), 2024, The Lancet, 403, 10431, 1027-1050. A1 Journal article (refereed), original research -
Association of omega 3 polyunsaturated fatty acids with incident chronic kidney disease: pooled analysis of 19 cohorts
Ong, Kwok Leung; Marklund, Matti; Huang, Liping; Rye, Kerry-Anne; Hui, Nicholas; Pan, Xiong-Fei; Rebholz, Casey M; Kim, Hyunju; Steffen, Lyn M; van Westing, Anniek C; Geleijnse, Johanna M; Hoogeveen, Ellen K; Chen, Yun-Yu; Chien, Kuo-Liong; Fretts, Amanda M; Lemaitre, Rozenn N; Imamura, Fumiaki; Forouhi, Nita G; Wareham, Nicholas J; Birukov, Anna; Jäger, Susanne; Kuxhaus, Olga; Schulze, Matthias B; de Mello, Vanessa Derenji; Tuomilehto, Jaakko; Uusitupa, Matti; Lindström, Jaana; Tintle, Nathan;, 2023, BMJ, 380, e072909. A1 Journal article (refereed), original research -
Dietary fat quality and serum androgen concentrations in middle-aged men
Wynne-Ellis, Miika M; Mursu, Jaakko J; Tuomainen, Tomi Pekka; Bertone-Johnson, Elizabeth; Salonen, Jukka T; Virtanen, Jyrki K, 2023, European journal of clinical nutrition, 2024; 78, 2, 99-106. A1 Journal article (refereed), original research -
Diminishing benefits of urban living for children and adolescents’ growth and development
NCD Risk Factor Collaboration (NCD-RisC), 2023, Nature, 615, 7954, 874-883. A1 Journal article (refereed), original research -
Efficacy of vitamin D3 supplementation on cancer mortality: systematic review and individual patient data meta-analysis of randomised controlled trials
Kuznia, Sabine; Zhu, Anna; Akutsu, Taisuke; Buring, Julie E; Camargo Jr, Carlos A; Cook, Nancy R; Chen, Li-Ju; Cheng, Ting-Yuan David; Hantunen, Sari; Lee, I-Min; Manson, JoAnn E; Neale, Rachel E; Scragg, Robert; Shadyab, Aladdin H; Sha, Sha; Sluyter, John; Tuomainen, Tomi-Pekka; Urashima, Mitsuyoshi; Virtanen, Jyrki K; Voutilainen, Ari; Wactawski-Wende, Jean; Waterhouse, Mary; Brenner, Hermann; Schöttker, Ben, 2023, Ageing research reviews, 87, 101923. A2 Review article, Literature review, Systematic review -
Global variation in diabetes diagnosis and prevalence based on fasting glucose and hemoglobin A1c
NCD Risk Factor Collaboration (NCD-RisC), 2023, Nature medicine, 29, 11, 2885-2901. A1 Journal article (refereed), original research -
Multiplicative, additive, and interactive associations of 25-hydroxyvitamin D with lung and prostate cancer
Voutilainen, Ari; Virtanen, Jyrki K; Hantunen, Sari; Nurmi, Tarja; Kokko, Petra; Tuomainen, Tomi-Pekka, 2023, International journal for vitamin and nutrition research, 2024; 94, 2, 133-142. A1 Journal article (refereed), original research -
Omega-3 Fatty Acid Biomarkers and Incident Atrial Fibrillation
Qian, Frank; Tintle, Nathan; Jensen, Paul N; Lemaitre, Rozenn N.; Imamura, Fumiaki; Feldreich, Tobias Rudholm; Nomura, Sarah Oppeneer; Guan, Weihua; Laguzzi, Federica; Kim, Eunjung; Virtanen, Jyrki K; Steur, Marinka; Bork, Christian S; Hirakawa, Yoichiro; O'Donoghue, Michelle L; Sala-Vila, Aleix; Ardisson Korat, Andres V.; Sun, Qi; Rimm, Eric B; Psaty, Bruce M; Heckbert, Susan R; Forouhi, Nita G; Wareham, Nicholas J; Marklund, Matti; Risérus, Ulf; Lind, Lars; Ärnlöv, Johan; Garg, Parveen; Tsai,, 2023, Journal of the american college of cardiology, 82, 4, 336-349. A1 Journal article (refereed), original research -
The effect of vitamin D3 supplementation on atrial fibrillation in generally healthy men and women: the Finnish Vitamin D Trial
Virtanen, Jyrki K; Hantunen, Sari; Lamberg-Allardt, Christel; Manson, JoAnn E; Nurmi, Tarja; Uusitupa, Matti; Voutilainen, Ari; Tuomainen, Tomi-Pekka, 2023, American heart journal, 264, 177-182. A1 Journal article (refereed), original research -
Vitamin D status and supplementation before and after Bariatric Surgery: Recommendations based on a systematic review and meta-analysis
Giustina, Andrea; di Filippo, Luigi; Facciorusso, Antonio; Adler, Robert A; Binkley, Neil; Bollerslev, Jens; Bouillon, Roger; Casanueva, Felipe F; Cavestro, Giulia Martina; Chakhtoura, Marlene; Conte, Caterina; Donini, Lorenzo M; Ebeling, Peter R; Fassio, Angelo; Frara, Stefano; Gagnon, Claudia; Latella, Giovanni; Marcocci, Claudio; Mechanick, Jeffrey I; Minisola, Salvatore; Rizzoli, René; Santini, Ferruccio; Shaker, Joseph L; Sempos, Christopher; Ulivieri, Fabio Massimo; Virtanen, Jyrki K; Napo, 2023, Reviews in endocrine and metabolic disorders, 24, 6, 1011-1029. A2 Review article, Literature review, Systematic review -
n–6 fatty acid biomarkers and incident atrial fibrillation: an individual participant-level pooled analysis of 11 international prospective studies
Garg, Parveen K; Guan, Weihua; Nomura, Sarah; Weir, Natalie L; Tintle, Nathan; Virtanen, Jyrki K; Hirakawa, Yoichiro; Qian, Frank; Sun, Qi; Rimm, Eric; Lemaitre, Rozenn N; Jensen, Paul N; Heckbert, Susan R; Imamura, Fumiaki; Steur, Marinka; Leander, Karin; Laguzzi, Federica; Voortman, Trudy; Ninomiya, Toshiharu; Mozaffarian, Dariush; Harris, William S; Siscovick, David S; Tsai, Michael Y, 2023, American journal of clinical nutrition, 118, 5, 921-929. A1 Journal article (refereed), original research -
Are Eggs a Superpower for the Brain and Memory?
Ylilauri, Maija PT; Virtanen, Jyrki K, 2022, Frontiers for young minds, 10, 10, 697754. E1 Popularised article, newspaper article -
Associations between total dairy, high-fat dairy and low-fat dairy intake, and depressive symptoms: findings from a population-based cross-sectional study
Hockey, Meghan; Mohebbi, Mohammadreza; Tolmunen, Tommi; Hantunen, Sari; Tuomainen, Tomi Pekka; Macpherson, Helen; Jacka, Felice N; Virtanen, Jyrki K; Rocks, Tetyana; Ruusunen, Anu, 2022, European journal of nutrition, 2023; 62, 1, 227-237. A1 Journal article (refereed), original research -
Associations of dairy, meat, and fish intakes with risk of incident dementia and with cognitive performance: the Kuopio Ischaemic Heart Disease Risk Factor Study (KIHD)
Ylilauri, Maija PT; Hantunen, Sari; Lönnroos, Eija; Salonen, Jukka T; Tuomainen, Tomi-Pekka; Virtanen, Jyrki K, 2022, European journal of nutrition, 61, 5, 2531-2542. A1 Journal article (refereed), original research -
Associations of fermented and non-fermented dairy consumption with serum C-reactive protein concentrations – A cross-sectional analysis
Voutilainen, Elisa K; Hantunen, Sari; Ruusunen, Anu; Tuomainen, Tomi-Pekka; Virtanen, Jyrki K, 2022, Clinical nutrition ESPEN, 48, 401-407. A1 Journal article (refereed), original research -
Associations of reproductive factors with postmenopausal follicle stimulating hormone
Costa, Rebecca; Tuomainen, Tomi-Pekka; Virtanen, Jyrki; Niskanen, Leo; Bertone-Johnson, Elizabeth, 2022, Women's midlife health, 8, 1, 8. A1 Journal article (refereed), original research -
Associations of serum n-3 and n-6 polyunsaturated fatty acids with prevalence and incidence of nonalcoholic fatty liver disease
Mäkelä, Tiia NK; Tuomainen, Tomi Pekka; Hantunen, Sari; Virtanen, Jyrki K, 2022, American journal of clinical nutrition, 116, 3, 759-770. A1 Journal article (refereed), original research -
Associations of the serum n-6 PUFA with exercise cardiac power in men
Esmaili, Haleh; Tajik, Behnam; Tuomainen, Tomi-Pekka; Kurl, Sudhir; Salonen, Jukka T; Virtanen, Jyrki K, 2022, British journal of nutrition, 2023; 129, 8, 1388-1397. A1 Journal article (refereed), original research -
Egg and cholesterol intake, apoE4 phenotype and risk of venous thromboembolism: findings from a prospective cohort study
Kunutsor, Setor K; Laukkanen, Jari A; Virtanen, Jyrki K, 2022, British journal of nutrition, 2023; 129, 2, 292-300. A1 Journal article (refereed), original research -
How competing risks affect the epidemiological relationship between vitamin D and prostate cancer incidence? A population‐based study
Voutilainen, Ari; Virtanen, Jyrki K.; Hantunen, Sari; Nurmi, Tarja; Kokko, Petra; Tuomainen, Tomi‐Pekka, 2022, Andrologia, 54, 6, e14410. A1 Journal article (refereed), original research -
Nonfermented Dairy Intake, but Not Fermented Dairy Intake, Associated with a Higher Risk of Depression in Middle-Age and Older Finnish Men
Hockey, Meghan; Hoare, Erin; Mohebbi, Mohammadreza; Tolmunen, Tommi; Hantunen, Sari; Tuomainen, Tomi-Pekka; Macpherson, Helen; Staudacher, Heidi; Jacka, Felice N; Virtanen, Jykri K; Rocks, Tetyana; Ruusunen, Anu, 2022, Journal of nutrition, 152, 8, 1916-1926. A1 Journal article (refereed), original research -
Nonoptimal Follow-up Times Make It Difficult to Detect the Epidemiological Inverse Relationship Between 25-Hydroxyvitamin D and Lung Cancer
Voutilainen, Ari; Virtanen, Jyrki K.; Hantunen, Sari; Nurmi, Tarja; Kokko, Petra; Tuomainen, Tomi-Pekka, 2022, Biostatistics Research (BSR), 1, 1, 1 - 10. D1 Article in a trade journal -
PUFA ω-3 and ω-6 biomarkers and sleep: a pooled analysis of cohort studies on behalf of the Fatty Acids and Outcomes Research Consortium (FORCE)
Murphy, Rachel A; Tintle, Nathan; Harris, William S; Darvishian, Maryam; Marklund, Matti; Virtanen, Jyrki K; Hantunen, Sari; de Mello, Vanessa D; Tuomilehto, Jaakko; Lindström, Jaana; Bolt, Matthew A; Brouwer, Ingeborg A; Wood, Alexis C; Senn, Mackenzie; Redline, Susan; Tsai, Michael Y; Gudnason, Vilmundur; Eiriksdottir, Gudny; Lindberg, Eva; Shadyab, Aladdin H; Liu, Buyun; Carnethon, Mercedes; Uusitupa, Matti; Djousse, Luc; Risérus, Ulf; Lind, Lars; van Dam, Rob M; Koh, Woon-Puay; Shi, Peilin;, 2022, American journal of clinical nutrition, 115, 3, 864-876. A1 Journal article (refereed), original research -
Serum metabolites associated with wholegrain consumption using nontargeted metabolic profiling: a discovery and reproducibility study
Noerman, Stefania; Virtanen, Jyrki K.; Lehtonen, Marko; Brunius, Carl; Hanhineva, Kati, 2022, European journal of nutrition, 2023; 62, 2, 713-726. A1 Journal article (refereed), original research -
Synergic Interaction of Vitamin D Deficiency and Renal Hyperfiltration on Mortality in Middle-Aged Men
Ould Setti, Mounir; Kacimi, Salah Eddine Oussama; Niskanen, Leo; Virtanen, Jyrki; Tuomainen, Tomi-Pekka, 2022, Journal of renal nutrition, 32, 6, 692-701. A1 Journal article (refereed), original research -
Urinary sodium concentration predicts time to major adverse coronary events and all-cause mortality in men with heart failure over a 28–33-year period: a prospective cohort study
Ganes, Anand; Davis, Jessica A.; Virtanen, Jyrki K.; Voutilainen, Ari; Tuomainen, Tomi-Pekka; Atherton, John J.; Amerena, John; Driscoll, Andrea; Hare, Dave L.; Wittert, Gary; Ruusunen, Anu; Marx, Wolfgang; Mohebbi, Mohammadreza; O’Neil, Adrienne, 2022, Bmc cardiovascular disorders, 22, 1, 391. A1 Journal article (refereed), original research -
Vitamin D supplementation and prevention of cardiovascular disease and cancer in the Finnish Vitamin D Trial: a randomized controlled trial
Virtanen, Jyrki K; Nurmi, Tarja; Aro, Antti; Bertone-Johnson, Elizabeth R; Hyppönen, Elina; Kröger, Heikki; Lamberg-Allardt, Christel; Manson, JoAnn E; Mursu, Jaakko; Mäntyselkä, Pekka; Suominen, Sakari; Uusitupa, Matti; Voutilainen, Ari; Tuomainen, Tomi-Pekka; Hantunen, Sari, 2022, American journal of clinical nutrition, 115, 5, 1300-1310. A1 Journal article (refereed), original research -
A healthy Nordic diet score and risk of incident CHD among men: the Kuopio Ischaemic Heart Disease Risk Factor Study
Tertsunen, Hanna-Mari; Hantunen, Sari; Tuomainen, Tomi-Pekka; Salonen, Jukka T; Virtanen, Jyrki K, 2021, British journal of nutrition, 2022; 127, 4, 599-606. A1 Journal article (refereed), original research -
Adherence to a healthy Nordic diet and risk of type 2 diabetes among men: the Kuopio Ischaemic Heart Disease Risk Factor Study
Tertsunen, Hanna-Mari; Hantunen, Sari; Tuomainen, Tomi-Pekka; Virtanen, Jyrki K, 2021, European journal of nutrition, 60, 7, 3927-3934. A1 Journal article (refereed), original research -
Associations of the serum metabolite profile with a healthy Nordic diet and risk of coronary artery disease
Noerman, Stefania; Kokla, Marietta; Koistinen, Ville M; Lehtonen, Marko; Tuomainen, Tomi-Pekka; Brunius, Carl; Virtanen, Jyrki K; Hanhineva, Kati, 2021, Clinical nutrition, 40, 5, 3250-3262. A1 Journal article (refereed), original research -
Blood n-3 fatty acid levels and total and cause-specific mortality from 17 prospective studies
Harris, William S; Tintle, Nathan L; Imamura, Fumiaki; Qian, Frank; Korat, Andres V Ardisson; Marklund, Matti; Djousse, Luc; Bassett, Julie K; Carmichael, Pierre-Hugues; Chen, Yun-Yu; Hirakawa, Yoichiro; Kupers, Leanne K; Laguzzi, Federica; Lankinen, Maria; Murphy, Rachel A; Samieri, Cecilia; Senn, Mackenzie K; Shi, Peilin; Virtanen, Jyrki K; Brouwer, Ingeborg A et al; The Fatty Acids and Outcomes Research Consortium (FORCE) [Incl Laakso, Markku; Mursu, Jaakko], 2021, Nature communications, 12, 1, 2329. A2 Review article, Literature review, Systematic review -
Serum n-6 polyunsaturated fatty acids and risk of atrial fibrillation: the Kuopio Ischaemic Heart Disease Risk Factor Study
Tajik, Behnam; Tuomainen, Tomi-Pekka; Isanejad, Masoud; Salonen, Jukka T; Virtanen Jyrki K, 2021, European journal of nutrition, [Published online 27 Dec 2021], 1-9. A1 Journal article (refereed), original research -
The associations between whole grain and refined grain intakes and serum C-reactive protein
Taskinen, Riikka E; Hantunen, Sari; Tuomainen, Tomi-Pekka; Virtanen, Jyrki K, 2021, European journal of clinical nutrition, [Published 17 August 2021], 1-7. A1 Journal article (refereed), original research -
Vexed causal inferences in nutritional epidemiology-call for genetic help
Ohukainen, P; Virtanen, JK; Ala-Korpela, M, 2021, International journal of epidemiology, 2022; 51, 1, 6-15. B1 Non-refereed journal articles -
Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants
NCD Risk Factor Collaboration (NCD-RisC); Zhou, Bin; Carrillo-Larco, Rodrigo M; Danaei, Goodarz; Riley, Leanne M; Paciorek, Christopher J; Stevens, Gretchen A; Gregg, Edward W; Bennett, James E; Solomon, Bethlehem; Singleton, Rosie K; Sophiea, Marisa K; Iurilli, Maria LC; Lhoste, Victor PF; Cowan, Melanie J; Savin, Stefan; Woodward, Mark; Balanova, Yulia; Cifkova, Renata; Damasceno, Albertino; Elliott, Paul [incl. Hantunen, Sari; Kauhanen, Jussi; Mursu, Jaakko; Tuomainen, Tomi-Pekka; Virtanen, J, 2021, The Lancet, 398, 10304, 957-980. A1 Journal article (refereed), original research -
n-3 Fatty Acid Biomarkers and Incident Type 2 Diabetes: An Individual Participant-Level Pooling Project of 20 Prospective Cohort Studies
Qian, Frank; Korat, Andres V Ardisson; Imamura, Fumiaki; Marklund, Matti; Tintle, Nathan; Virtanen, Jyrki K; Zhou, Xia; Bassett, Julie K; Lai, Heidi; Hirakawa, Yoichiro; Chien, Kuo-Liong; Wood, Alexis C; Lankinen, Maria; Murphy, Rachel A; Samieri, Cecilia; Pertiwi, Kamalita; de Mello, Vanessa D; Guan, Weihua; Forouhi, Nita G; Wareham, Nick et al. (Incl Laakso, Markku), 2021, Diabetes care, 44, 5, 1133-1142. A1 Journal article (refereed), original research -
Aina ajankohtainen D-vitamiini - uutta tietoa ihon ja aurinkosuojavoiteiden roolista
Virtanen, Jyrki; Hantunen, Sari, 2020, Duodecim, 136, 22, 2441-2443. D1 Article in a trade journal -
Changes in circulating metabolome precede alcohol-related diseases in middle-aged men: a prospective population-based study with a 30-year follow-up
Kärkkäinen, Olli; Klåvus, Anton; Voutilainen, Ari; Virtanen, Jyrki; Lehtonen, Marko; Auriola, Seppo; Kauhanen, Jussi; Rysä, Jaana, 2020, Alcoholism-clinical and experimental research, 44, 12, 2457-2467. A1 Journal article (refereed), original research -
Common and personal target genes of the micronutrient vitamin D in primary immune cells from human peripheral blood
Hanel, Andrea; Neme, Antonio; Malinen, Marjo; Hämäläinen, Emmi; Malmberg, Henna-Riikka; Etheve, Stéphane; Tuomainen, Tomi-Pekka; Virtanen, Jyrki K; Bendik, Igor; Carlberg, Carsten, 2020, Scientific reports, 10, 1, 21051. A1 Journal article (refereed), original research -
D-vitamiini syövän ehkäisyssä - totta vai tarua?
Hantunen, Sari; Virtanen, Jyrki, 2020, Duodecim, 136, 6, 601-603. D1 Article in a trade journal -
Dietary intake of choline and phosphatidylcholine and risk of type 2 diabetes in men: The Kuopio Ischaemic Heart Disease Risk Factor Study
Virtanen, Jyrki; Tuomainen, Tomi-Pekka; Voutilainen, Sari, 2020, European journal of nutrition, 59, 8, 3857-3861. A1 Journal article (refereed), original research -
Fatty acids in the de novo lipogenesis pathway and incidence of type 2 diabetes: A pooled analysis of prospective cohort studies
Imamura, Fumiaki; Fretts, Amanda M; Marklund, Matti; Ardisson Korat, Andres V; Yang, Wei-Sin; Lankinen, Maria; Qureshi, Waqas; Helmer, Catherine; Chen, Tzu-An; Virtanen, Jyrki K; Wong, Kerry; Bassett, Julie K; Murphy, Rachel; Tintle, Nathan; Yu, Chaoyu Ian; Brouwer, Ingeborg A; Chien, Kuo-Liong; Chen, Yun-Yu; Wood, Alexis C; Del Gobbo, Liana C et al [incl. Laakso, Markku; Tuomainen, Tomi-Pekka; Uusitupa, Matti], 2020, PLoS medicine, 17, 6, e1003102. A1 Journal article (refereed), original research -
Healthy Nordic Diet and Risk of Disease Death Among Men: The Kuopio Ischaemic Heart Disease Risk Factor Study
Tertsunen, H-M; Hantunen, S; Tuomainen, T-P; Virtanen, JK, 2020, European journal of nutrition, 59, 8, 3545-3553. A1 Journal article (refereed), original research -
Repositioning of the global epicentre of non-optimal cholesterol
Taddei, Cristina; Zhou, Bin; Bixby, Honor; Carrillo-Larco, Rodrigo M; Danaei, Goodarz; Jackson, Rod T; Farzadfar, Farshad; Sophiea, Marisa K; Di Cesare, Mariachiara; Iurilli, Maria LC; Rodriguez Martinez, Andrea; Asghari, Golaleh; Dhana, Klodian; Gulayin, Pablo; Kakarmath, Sujay; Santero, Marilina; Voortman, Trudy; Riley, Leanne M.; Cowan, Melanie J.; Savin, Stefan et al. (incl. Hantunen, Sari; Kauhanen, Jussi; Mursu, Jaakko; Tuomainen, Tomi-Pekka; Virtanen, Jyrki K; Voutilainen, Ari), 2020, Nature, 582, 7810, 73-77. A1 Journal article (refereed), original research -
Serum copper-to-zinc-ratio and risk of incident infection in men: the Kuopio Ischaemic Heart Disease Risk Factor Study
Laine, Jaakko; Tuomainen, Tomi-Pekka; Salonen, Jukka; Virtanen, Jyrki, 2020, European journal of epidemiology, 35, 12, 1149-1156. A1 Journal article (refereed), original research -
Association of fatty liver disease with mortality outcomes in an Eastern Finland male cohort
Olubamwo, Olubunmi O; Virtanen, Jyrki K; Pihlajamäki, Jussi; Tuomainen, Tomi-Pekka, 2019, BMJ open gastroenterology, 6, 1, e000219. A1 Journal article (refereed), original research -
Association of fatty liver index with risk of incident type 2 diabetes by metabolic syndrome status in an Eastern Finland male cohort: a prospective study
Olubamwo, OO; Virtanen, JK; Pihlajamaki, J; Tuomainen, TP, 2019, BMJ open, 9, 7, e026949. A1 Journal article (refereed), original research -
Associations of circulating very-long-chain saturated fatty acids and incident type 2 diabetes: a pooled analysis of prospective cohort studies
Fretts, AM; Imamura, F; Marklund, M; Micha, R; Wu, JHY; Murphy, RA; Chien, KL; McKnight, B; Tintle, N; Forouhi, NG; Qureshi, WT; Virtanen, JK; Wong, K; Wood, AC; Lankinen, M; Rajaobelina, K; Harris, TB; et al (incl; Laakso, M; Uusitupa, M; Voutilainen, S), 2019, American journal of clinical nutrition, 109, 4, 1216-1223. A1 Journal article (refereed), original research -
Associations of dietary choline intake with risk of incident dementia and with cognitive performance: the Kuopio Ischaemic Heart Disease Risk Factor Study
Ylilauri, MPT; Voutilainen, S; Lönnroos, E; Virtanen, HEK; Tuomainen, TP; Salonen, JT; Virtanen, JK, 2019, American journal of clinical nutrition, 110, 6, 1416-1423. A1 Journal article (refereed), original research -
Biomarkers of Dietary Omega-6 Fatty Acids and Incident Cardiovascular Disease and Mortality: An Individual-Level Pooled Analysis of 30 Cohort Studies
Marklund, M; Wu, JHY; Imamura,;F, Del Gobbo, LC; Fretts, A; de Goede, J; Shi, P; Tintle, N; Wennberg, M; Aslibekyan, S; Chen, TA; de Oliveira Otto, MC; Hirakawa, Y; Eriksen, HH; Kröger, J; Jaguzzi, F; Lankinen, M; Murphy, Rachel A; Prem, Kiesha; Samieri, Cécilia; et al. (incl. Uusitupa, M; Mursu J; Laakso, M; Virtanen, J), 2019, Circulation, 139, 21, 2422-2436. A1 Journal article (refereed), original research -
Dietary proteins and protein sources and risk of death: the Kuopio Ischaemic Heart Disease Risk Factor Study
Virtanen, HEK; Voutilainen, S; Koskinen, TT; Mursu, J; Kokko, P; Ylilauri, MPT; Tuomainen, TP; Salonen, JT; Virtanen, JK, 2019, American journal of clinical nutrition, 109, 5, 1462-1471. A1 Journal article (refereed), original research -
Egg consumption, cholesterol intake, and risk of incident stroke in men: the Kuopio Ischaemic Heart Disease Risk Factor Study
Abdollahi, AM; Virtanen, HEK; Voutilainen, S; Kurl, S; Tuomainen, TP; Salonen, JT; Virtanen, JK, 2019, American journal of clinical nutrition, 110, 1, 169-176. A1 Journal article (refereed), original research -
Fatty liver index as a predictor of increased risk of cardiometabolic disease: finding from the Kuopio Ischaemic Heart Disease Risk Factor Study Cohort
Olubamwo OO, Virtanen JK, Pihlajamaki J, Mantyselka P, Tuomainen TP, 2019, BMJ open, 9, 9, e031420. A1 Journal article (refereed), original research -
In vivo transcriptome changes of human white blood cells in response to vitamin D
Neme, Antonio; Seuter, Sabine; Malinen, Marjo; Nurmi, Tarja; Tuomainen, Tomi-Pekka; Virtanen, Jyrki K; Carlberg, Carsten, 2019, Journal of steroid biochemistry and molecular biology, 188, 71-76. A1 Journal article (refereed), original research -
National trends in total cholesterol obscure heterogeneous changes in HDL and non-HDLcholesterol and total-to-HDL cholesterol ratio: a pooled analysis of 458 population-based studiesin Asian and Western countries
NCD Risk Factor Collaboration; Taddei, C; Jackson, R; Zhou, B; Bixby, H; Danaei, G; Di Cesare, M; Kuulasmaa, K; Hajifathalian, K; Bentham, J; Bennett, JE; Aekplakorn, W; Cifkova, R; Dallongeville, J; De Bacquer, D; Giampaoli, S; Gudnason, V; Khang, YH; Laatikainen, T; Mann, JI; Marques-Vidal, P et al. (incl. Kauhanen, J; Mursu, J; Ronkainen, K; Tuomainen TP; Virtanen, JK; Voutilainen, S), 2019, International journal of epidemiology, 2020; 49, 1, 173-192. A1 Journal article (refereed), original research -
Random forest-based imputation outperforms other methods for imputing LC-MS metabolomics data: a comparative study
Kokla, M; Virtanen, J; Kolehmainen, M; Paananen, J; Hanhineva, K, 2019, Bmc bioinformatics, 20, 1, 492. A1 Journal article (refereed), original research -
Rising rural body-mass index is the main driver of the global obesity epidemic in adults
Bixby, Honor; Bentham, James; Zhou, Bin; Di Cesare, Mariachiara; Paciorek, Christopher J; Bennett, James E; Taddei, Cristina; Stevens, Gretchen A; Rodriguez-Martinez, Andrea; Carrillo-Larco, Rodrigo M; Khang, Young-Ho; Soric, Maroje; Gregg, Edward W; Miranda, J Jaime; Bhutta, Zulfiqar A; Savin, Stefan; Sophiea, Marisa K; Iurilli, Maria L C; Solomon, Bethlehem D; Cowan, Melanie J et al (Incl Kauhanen, Jussi; Mursu, Jaakko; Tuomainen, Tomi-Pekka; Virtanen, Jyrki K; Voutilainen, Ari; Voutilainen, S, 2019, Nature, 569, 260-264. A1 Journal article (refereed), original research -
Serum long-chain omega-3 fatty acids, hair mercury and exercise-induced myocardial ischaemia in men
Tajik, Behnam; Tuomainen, Tomi-Pekka; Kurl, Sudhir; Salonen, Jukka; Virtanen, Jyrki K, 2019, Heart, 105, 18, 1395-1401. A1 Journal article (refereed), original research -
Association of fatty liver index with the risk of incident cardiovascular disease and acute myocardial infarction.
Olubamwo, Olubamwo O; Virtanen, Jyrki K; Voutilainen, Ari; Kauhanen, Jussi; Pihlajamäki, Jussi; Tuomainen, Tomi-Pekka, 2018, European journal of gastroenterology and hepatology, 30, 9, 1047-1054. A1 Journal article (refereed), original research -
Contributions of mean and shape of blood pressure distribution to worldwide trends and variations in raised blood pressure: a pooled analysis of 1018 population-based measurement studies with 88.6 million participants
Zhou B, Bentham J, Di Cesare M, Bixby H, Danaei G, Hajifathalian K, Taddei C, Carrillo-Larco RM, Djalalinia S, Khatibzadeh S, Lugero, C; Peykari, N; Zhang, WZ; Bennett, J; Bilano, V; Stevens, GA; Cowan, MJ; Riley, LM; Chen, Z; Hambleton, IR; et al [Incl Laatikainen, Tiina; Kauhanen, Jussi; Mursu, Jaakko; Tuomainen, Tomi-Pekka; Virtanen, Jyrki; Voutilainen, Sari], 2018, International journal of epidemiology, 47, 3, 872-883i. A1 Journal article (refereed), original research -
Follicle-stimulating hormone is associated with lipids in postmenopausal women
Serviente, Corinna; Tuomainen, Tomi-Pekka; Virtanen, Jyrki; Witkowski, Saraha; Niskanen, Leo; Bertone-Johnson, Elizabeth, 2018, Menopause: the journal of the north american menopause society, 2019; 26, 5, 540-545. A1 Journal article (refereed), original research -
In vivo response of the human epigenome to vitamin D: A proof-of-principle study
Carlberg, Carsten; Seuter, Sabine; Nurmi, Tarja; Tuomainen, Tomi-Pekka; Virtanen, Jyrki K; Neme, Antonio, 2018, Journal of steroid biochemistry and molecular biology, 180, 142-148. A1 Journal article (refereed), original research -
Intake of Different Dietary Proteins and Risk of Heart Failure in Men The Kuopio Ischaemic Heart Disease Risk Factor Study
Virtanen, Heli EK; Voutilainen, Sari; Koskinen, Timo T; Mursu, Jaakko; Tuomainen, Tomi-Pekka; Virtanen, Jyrki K, 2018, Circulation: heart failure, 11, 6, e004531. A1 Journal article (refereed), original research -
Intake of fermented and non-fermented dairy products and risk of incident CHD: The Kuopio Ischaemic Heart Disease Risk Factor Study
Koskinen, Timo T; Virtanen, Heli EK; Voutilainen, Sari; Tuomainen, Tomi-Pekka; Mursu, Jaakko; Virtanen, Jyrki K, 2018, British journal of nutrition, 120, 11, 1288-1297. A1 Journal article (refereed), original research -
Metabolic Profiling of High Egg Consumption and the Associated Lower Risk of Type 2 Diabetes in Middle-Aged Finnish Men
Noerman, S; Kärkkäinen, O; Mattsson, A; Paananen, J; Lehtonen, M; Nurmi, T; Tuomainen, TP; Voutilainen, S; Hanhineva, K; Virtanen, JK, 2018, Molecular nutrition and food research, 2019; 63, 5, 1800605. A1 Journal article (refereed), original research -
Randomized trials of replacing saturated fatty acids with n-6 polyunsaturated fatty acids in coronary heart disease prevention: Not the gold standard?
Virtanen, Jyrki K, 2018, Prostaglandins leukotrienes and essential fatty acids, 133, 8-15. A2 Review article, Literature review, Systematic review -
Serum Adiponectin/Ferritin Ratio in Relation to the Risk of Type 2 diabetes and Insulin Sensitivity
Aregbesola, A; de Mello, VDF; Lindström, J; Voutilainen, S; Virtanen, JK; Keinänen-Kiukaanniemi, S; Tuomainen, TP; Tuomilehto, J; Uusitupa, M, 2018, Diabetes research and clinical practice, 141, 264-274. A1 Journal article (refereed), original research -
Serum n-6 polyunsaturated fatty acids and risk of death: the Kuopio Ischaemic Heart Disease Risk Factor Study
Virtanen, Jyrki K; Wu, Jason HY; Voutilainen, Sari; Mursu, Jaakko; Tuomainen, Tomi-Pekka, 2018, American journal of clinical nutrition, 107, 3, 427-435. A1 Journal article (refereed), original research -
Association between serum zinc and later development of metabolic syndrome in middle aged and older men: The Kuopio Ischaemic Heart Disease Risk Factor Study
Yary T, Virtanen JK, Ruusunen A, Tuomainen TP, Voutilainen S, 2017, Nutrition, 37, 43-47. A1 Journal article (refereed), original research -
Association of dietary cholesterol and egg intakes with the risk of incident dementia or Alzheimer disease: the Kuopio Ischaemic Heart Disease Risk Factor Study
Ylilauri, Maija PT; Voutilainen, Sari; Lönnroos, Eija; Mursu, Jaakko; Virtanen, Heli EK; Koskinen, Timo T; Salonen, Jukka T; Tuomainen, Tomi-Pekka; Virtanen, Jyrki K, 2017, American journal of clinical nutrition, 105, 2, 476-484. A1 Journal article (refereed), original research -
Association of follicle-stimulating hormone levels and risk of type 2 diabetes in older postmenopausal women
Bertone-Johnson ER, Virtanen JK, Niskanen L, Nurmi T, Ronkainen K, Voutilainen S, Mursu J, Kauhanen J, Tuomainen T-P, 2017, Menopause: the journal of the north american menopause society, 24, 7, 796-802. A1 Journal article (refereed), original research -
Associations of estimated delta-5-desaturase and delta-6-desaturase activities with stroke risk factors and risk of stroke: the Kuopio Ischaemic Heart Disease Risk Factor Study
Daneshmand R, Kurl S, Tuomainen TP, Virtanen JK, 2017, British journal of nutrition, 117, 4, 582-590. A1 Journal article (refereed), original research -
Associations of the serum long-chain n-3 PUFA and hair mercury with resting heart rate, peak heart rate during exercise and heart rate recovery after exercise in middle-aged men
Tajik Behnam, Kurl Sudhir, Tuomainen Tomi-Pekka, Savonen Kai, Virtanen Jyrki K, 2017, British journal of nutrition, 2018; 119, 1, 66-73. A1 Journal article (refereed), original research -
Follicle-Stimulating Hormone Levels and Subclinical Atherosclerosis in Older Postmenopausal Women
Bertone-Johnson ER, Virtanen JK, Nurmi T, Niskanen L, Mursu J, Voutilainen S, Ronkainen K, Kauhanen J, Tuomainen TP, 2017, American journal of epidemiology, 2018; 187, 1, 16-26. A1 Journal article (refereed), original research -
Intake of different dietary proteins and risk of type 2 diabetes in men: the Kuopio Ischaemic Heart Disease Risk Factor Study
Virtanen HEK, Koskinen TT, Voutilainen S, Mursu J, Tuomainen TP, Kokko P, Virtanen JK, 2017, British journal of nutrition, 117, 6, 882-893. A1 Journal article (refereed), original research -
Low serum 25-hydroxyvitamin D is associated with higher risk of frequent headache in middle-aged and older men
Virtanen JK, Giniatullin R, Mäntyselkä P, Voutilainen S, Nurmi T, Mursu J, Kauhanen J, Tuomainen TP, 2017, Scientific reports, 7, 39697. A1 Journal article (refereed), original research -
Molecular evaluation of vitamin D responsiveness of healthy young adults
Seuter Sabine, Virtanen Jyrki K, Nurmi Tarja, Pihlajamäki Jussi, Mursu Jaakko, Voutilainen Sari, Tuomainen Tomi-Pekka, Neme Antonio, Carlberg Carsten, 2017, Journal of steroid biochemistry and molecular biology, 174, 314-321. A1 Journal article (refereed), original research -
Omega-6 fatty acid biomarkers and incident type 2 diabetes: pooled analysis of individual-level data for 39 740 adults from 20 prospective cohort studies
Wu JHY, Marklund M, Imamura F, Tintle N, Ardisson Korat AV, de Goede J, Zhou X, Yang WS, de Oliveira Otto MC, Kröger J, Qureshi W, Virtanen JK, Bassett JK, Frazier-Wood AC, Lankinen M, Murphy RA, Rajaobelina K, Del Gobbo LC, Forouhi NG, Luben R, Khaw KT, Wareham N, Kalsbeek A, Veenstra J, Luo J, Hu FB, Lin HJ, Siscovick DS, Boeing H, Chen TA, Steffen B, Steffen LM, Hodge A, Eriksdottir G, Smith AV, Gudnason V, Harris TB, Brouwer IA, Berr C, Helmer C, Samieri C, Laakso M, Tsai MY, Giles GG, Nurmi, 2017, The Lancet Diabetes & Endocrinology, 5, 12, 965-974. A1 Journal article (refereed), original research -
Serum concentrations of 25-hydroxyvitamin D and depression in a general middle-aged to elderly population in Finland
Vidgren M, Virtanen JK, Tolmunen T, Tuomainen T-P, Voutilainen S, Ruusunen A, 2017, Journal of nutrition health and aging, 2018; 22, 1, 159-164. A1 Journal article (refereed), original research -
The associations of serum n-6 polyunsaturated fatty acids with serum C-reactive protein in men: the Kuopio Ischaemic Heart Disease Risk Factor Study
Virtanen Jyrki K, Mursu Jaakko, Voutilainen Sari, Tuomainen Tomi-Pekka, 2017, European journal of clinical nutrition, 2018; 72, 3, 342-348. A1 Journal article (refereed), original research -
Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: a pooled analysis of 2416 population-based measurement studies in 128·9 million children, adolescents, and adults
Abarca-Gómez L, Abdeen ZA, Hamid ZA, Abu-Rmeileh NM, Acosta-Cazares B, Acuin C, Adams RJ, Aekplakorn W, Afsana K, Aguilar-Salinas CA, Agyemang C, Ahmadvand A, Ahrens W, Ajlouni K, Akhtaeva N, Al-Hazzaa HM, Al-Othman AR, Al-Raddadi R, Al Buhairan F, Al Dhukair S et al., NCD Risk Factor Collaboration (NCD-RisC), 2017, The Lancet, 390, 10113, 2627-2642. A1 Journal article (refereed), original research -
A century of trends in adult human height
NCD Risk Factor Collaboration (multiple authors including Mursu Jaakko, Ronkainen Kimmo, Tuomainen Tomi-Pekka, Virtanen Jyrki, Voutilainen Sari, Laatikainen Tiina), 2016, eLife, 5, e13410. A1 Journal article (refereed), original research -
Association between serum long-chain omega-3 polyunsaturated fatty acids and cognitive performance in elderly men and women: The Kuopio Ischaemic Heart Disease Risk Factor Study
D'Ascoli TA, Mursu J, Voutilainen S, Kauhanen J, Tuomainen T-P, Virtanen JK, 2016, European journal of clinical nutrition, [epub ahead of print 13 Apr 2016]. A1 Journal article (refereed), original research -
Associations of egg and cholesterol intakes with carotid intima-media thickness and risk of incident coronary artery disease according to apolipoprotein E phenotype in men: the Kuopio Ischaemic Heart Disease Risk Factor Study
Virtanen JK, Mursu J, Virtanen HE, Fogelholm M, Salonen JT, Koskinen TT, Voutilainen S, Tuomainen TP, 2016, American journal of clinical nutrition, 103, 3, 895-901. A1 Journal article (refereed), original research -
Associations of serum n-3 and n-6 PUFA and hair mercury with the risk of incident stroke in men: the Kuopio Ischaemic Heart Disease Risk Factor Study (KIHD)
Daneshmand Roya, Kurl Sudhir, Tuomainen Tomi-Pekka, Virtanen Jyrki K, 2016, British journal of nutrition, 115, 10, 1851-1859. A1 Journal article (refereed), original research -
Associations of serum n-3 and n-6 polyunsaturated fatty acids with plasma natriuretic peptides
Daneshmand R, Kurl S, Tuomainen TP, Virtanen JK, 2016, European journal of clinical nutrition, 70, 963-969. A1 Journal article (refereed), original research -
Associations of the serum long-chain omega-3 polyunsaturated fatty acids and hair mercury with heart rate-corrected QT and JT intervals in men: the Kuopio Ischaemic Heart Disease Risk Factor Study
Tajik B, Kurl S, Tuomainen T-P, Virtanen JK, 2016, European journal of nutrition, 56, 7, 2319-2327. A1 Journal article (refereed), original research -
Egg consumption and risk of incident type 2 diabetes: a dose-response meta-analysis of prospective cohort studies
Tamez M, Virtanen JK, Lajous M, 2016, British journal of nutrition, 115, 12, 2212-2218. A1 Journal article (refereed), original research -
Gender difference in type 2 diabetes and the role of body iron stores
Aregbesola Alex, Voutilainen Sari, Virtanen Jyrki K, Mursu Jaakko, Tuomainen Tomi-Pekka, 2016, Annals of clinical biochemistry, [epub ahead of print May 10, 2016]. A1 Journal article (refereed), original research -
Omega-3 Polyunsaturated fatty acid biomarkers and coronary heart disease: Pooling project of 19 cohort studies
Del Gobbo LC, Imamura F, Aslibekyan S, Marklund M, Virtanen JK, Wennberg M, Yakoob MY, Chiuve SE, Dela Cruz L, Frazier-Wood AC, Fretts AM, Guallar E, Matsumoto C, Prem K, Tanaka T, Wu JHY, Zhou X, Helmer C, Ingelsson E, Yuan J-M et al., for the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Fatty Acids and Outcomes Research Consortium (FORCe), 2016, JAMA internal medicine, 176, 8, 1155-1166. A1 Journal article (refereed), original research -
Omega-6 polyunsaturated fatty acids, serum zinc, delta-5- and delta-6-desaturase activities and incident metabolic syndrome
Yary T, Voutilainen S, Tuomainen TP, Ruusunen A, Nurmi T, Virtanen JK, 2016, Journal of human nutrition and dietetics, 30, 4, 506-514. A1 Journal article (refereed), original research -
Serum long-chain omega-3 polyunsaturated fattty acids and risk of orthostatic hypotension
Nyantika Asenath N, Tuomainen Tomi-Pekka, Kauhanen Jussi, Voutilainen Sari, Virtanen Jyrki K, 2016, Hypertension research, [epub ahead of print 25 Feb 2016]. A1 Journal article (refereed), original research -
Serum n-6 polyunsaturated fatty acids, delta5- and delta6-desaturase activities, and risk of incident type 2 diabetes in men: the Kuopio Ischaemic Heart Disease Risk Factor Study
Yary Teymoor, Voutilainen Sari, Tuomainen Tomi-Pekka, Ruusunen Anu, Nurmi Tarja, Virtanen Jyrki K, 2016, American journal of clinical nutrition, 103, 5, 1337-1343. A1 Journal article (refereed), original research -
The association of serum long-chain n-3 PUFA and hair mercury with exercise cardiac power in men
Tajik B, Kurl S, Tuomainen T-P, Virtanen JK, 2016, British journal of nutrition, 116, 3, 487-95. A1 Journal article (refereed), original research -
Trends in adult body-mass index in 200 countries from 1975 to 2014: a pooled analysis of 1698 population-based measurement studies with 19,2 million participants
NCD Risk Factor Collaboration (incl. Mursu Jaakko, Tuomainen Tomi-Pekka, Virtanen Jyrki, Voutilainen Sari, Ronkainen Kimmo, Laatikainen Tiina), 2016, The Lancet, 387, 10026, 1377-96. A1 Journal article (refereed), original research -
Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants
NCD Risk Factor Collaboration (including Laatikainen Tiina, Kauhanen Jussi, Mursu Jaakko, Tuomainen Tomi-Pekka, Virtanen Jyrki K, Voutilainen Sari), 2016, The Lancet, 2017; 389, 10064, 37-55. A1 Journal article (refereed), original research -
Worldwide trends in diabetes since 1980: a pooled analysis of 751 population-based studies with 4,4 million participants
NCD Risk Factor Collaboration (incl. Mursu Jaakko, Tuomainen Tomi-Pekka, Virtanen Jyrki, Voutilainen Sari, Ronkainen Kimmo, Laatikainen Tiina), 2016, The Lancet, 387, 10027, 1513-1530. A1 Journal article (refereed), original research -
Dietary polyunsaturated fat intake in coronary heart disease risk
Virtanen Jyrki K, 2015, Clinical lipidology, 10, 2, 115-117. B1 Non-refereed journal articles -
Effects of diabetes definition on global surveillance of diabetes prevalence and diagnosis: a pooled analysis of 96 population-based studies with 331288 participants
Danaei Goodarz, Fahimi Saman, Lu Yuan, Zhou Bin, Hajifathalian Kaveh, Di Cesare Mariachiara, Lo Wei-Cheng, Reis-Santos Barbara, Cowan Melanie J, Shaw Jonathan E, Bentham James, Lin John K, Bixby Honor, Magliano Dianna, Bovet Pascal, Miranda J Jaime, Khang Young-Ho, Stevens Gretchen A, Riley Leanne M, Ali Mohammed K, Ezzati Majid et al; NCD Risk Factor Collaboration (NCD-RisC), 2015, The Lancet Diabetes & Endocrinology, 3, 8, 624-637. A1 Journal article (refereed), original research -
Egg consumption and risk of incident type 2 diabetes in men: the Kuopio Ischaemic Heart Disease Risk Factor Study
Virtanen Jyrki K, Mursu Jaakko, Tuomainen Tomi-Pekka, Virtanen Heli EK, Voutilainen Sari, 2015, American journal of clinical nutrition, 101, 5, 1088-1096. A1 Journal article (refereed), original research -
Glucose Metabolism Effects of Vitamin D in Prediabetes: the VitDmet Randomized Placebo-Controlled Supplementation Study
Tuomainen Tomi-Pekka, Virtanen Jyrki K, Voutilainen Sari, Nurmi Tarja, Mursu Jaakko, de Mello Vanessa DF, Schwab Ursula, Hakumäki Martti, Pulkki Kari, Uusitupa Matti, 2015, Journal of Diabetes Research, 2015, 8 pages. A1 Journal article (refereed), original research -
Relevance of Vitamin D Receptor Target Genes for Monitoring the Vitamin D Responsiveness of Primary Human Cells
Vukic Maja, Neme Antonio, Seuter Sabine, Saksa Noora, de Mello Vanessa DF, Nurmi Tarja, Uusitupa Matti, Tuomainen Tomi-Pekka, Virtanen Jyrki K, Carlberg Carsten, 2015, PLoS ONE, 10, 4, e0124339. A1 Journal article (refereed), original research -
Reply to T Kawada
Virtanen Jyrki K, Mursu Jaakko, Tuomainen Tomi-Pekka, Virtanen Heli EK, Voutilainen Sari, 2015, American journal of clinical nutrition, 102, 4, 974-975. B1 Non-refereed journal articles -
Serum hepcidin concentrations and type 2 diabetes
Aregbesola Alex, Voutilainen Sari, Virtanen Jyrki K, Aregbesola Adeola, Tuomainen Tomi-Pekka, 2015, World journal of diabetes, 6, 7, 978-982. A1 Journal article (refereed), original research -
Serum long-chain omega-3 polyunsaturated fatty acids and future blood pressure in an ageing population
Nyantika AN, Tuomainen T-P, Kauhanen J, Voutilainen S, Virtanen Jyrki K, 2015, Journal of nutrition health and aging, 19, 5, 498-503. A1 Journal article (refereed), original research -
Serum zinc and risk of type 2 diabetes incidence in men: The Kuopio Ischaemic Heart Disease Risk Factor Study
Yary Teymoor, Virtanen Jyrki K, Ruusunen Anu, Tuomainen Tomi-Pekka, Voutilainen Sari, 2015, Journal of trace elements in medicine and biology, 2016; 33, 120-124. A1 Journal article (refereed), original research -
The association between serum 25-hydroxyvitamin D3 concentration and risk of disease death in men: modification by magnesium intake
Mursu Jaakko, Nurmi Tarja, Voutilainen Sari, Tuomainen Tomi-Pekka, Virtanen Jyrki K, 2015, European journal of epidemiology, 30, 4, 343-347. A1 Journal article (refereed), original research -
Changes in vitamin D target gene expression in adipose tissue monitor the vitamin D response of human individuals
Ryynänen Jussi, Neme Antonio, Tuomainen Tomi-Pekka, Virtanen Jyrki K, Voutilainen Sari, Nurmi Tarja, de Mello Vanessa DF, Uusitupa Matti, Carlberg Carsten, 2014, Molecular nutrition and food research, 58, 2036-2045. A1 Journal article (refereed), original research -
Dietary Fatty Acids and Risk of Coronary Heart Disease in Men: The Kuopio Ischemic Heart Disease Risk Factor Study
Virtanen Jyrki K, Mursu Jaakko, Tuomainen Tomi-Pekka, Voutilainen Sari, 2014, Arteriosclerosis, thrombosis, and vascular biology, Epub ahead of print. A1 Journal article (refereed), original research -
Dissecting high from low responders in a vitamin D3 intervention study
Saksa Noora, Neme Antonio, Ryynänen Jussi, Uusitupa Matti, de Mello Vanessa DF, Voutilainen Sari, Nurmi Tarja, Virtanen Jyrki K, Tuomainen Tomi-Pekka, Carlberg Carsten, 2014, Journal of steroid biochemistry and molecular biology, Epub ahead of print. A1 Journal article (refereed), original research -
Intake of fruit, berries, and vegetables and risk of type 2 diabetes in Finnish men: the Kuopio Ischaemic Heart Disease RiskFactor Study
Mursu Jaakko, Virtanen Jyrki K, Tuomainen Tomi-Pekka, Nurmi Tarja, Voutilainen Sari, 2014, American journal of clinical nutrition, 99, 2, 328-333. A1 Journal article (refereed), original research -
Primary vitamin D receptor target genes as biomarkers for the vitamin D3 status in the hematopoietic system
Wilfinger Julia, Seuter Sabine, Tuomainen Tomi-Pekka, Virtanen Jyrki K, Voutilainen Sari, Nurmi Tarja, de Mello Vanessa DF, Uusitupa Matti, Carlberg Carsten, 2014, Journal of nutritional biochemistry, 25, 8, 875-884. A1 Journal article (refereed), original research -
Serum ferritin and glucose homeostasis: change in the association by glycemic state
Aregbesola Alex, Virtanen Jyrki K, Voutilainen Sari, Mursu Jaakko, Lagundoye Ayodele, Kauhanen Jussi, Tuomainen Tomi-Pekka, 2014, Diabetes/metabolism research and reviews, Epub ahead of print. A1 Journal article (refereed), original research -
Body iron stores and the risk of type 2 diabetes in middle-aged men
Aregbesola A, Voutilainen S, Virtanen JK, Mursu J, Tuomainen T-P, 2013, European journal of endocrinology, 169, 247-253. A1 Journal article (refereed), original research -
Circulating omega-3 polyunsaturated fatty acids and subclinical brain abnormalities on MRI in older adults
Virtanen JK, Siscovick DS, Lemaitre RN, Longstreth WT, Spiegelman D, Rimm EB, King IB, Mozaffarian D, 2013, JAMA : Journal of the American Medical Association, 2, 5, e000305. A1 Journal article (refereed), original research -
High-performance liquid chromatography and coulometric electrode array detector in serum 25-hydroxyvitamin D3 and 25-hydroxyvitamin D2 analyses
Nurmi T, Tuomainen T-P, Virtanen J, Mursu J, Voutilainen S, 2013, Analytical biochemistry, 435, 1-9. A1 Journal article (refereed), original research -
Primary vitamin D target genes allow a categorization of possible benefits of vitamin D3 supplementation
Carlberg C, Seuter S, de Mello VDF, Schwab U, Voutilainen S, Pulkki K, Nurmi T, Virtanen J, Tuomainen T-P, Uusitupa M, 2013, PLoS ONE, 8, 7, e71042. A1 Journal article (refereed), original research -
Serum 25-hydroxyvitamin D3 and the risk of pneumonia in an ageing general population
Aregbesola A, Voutilainen S, Nurmi T, Virtanen JK, Ronkainen K, Tuomainen T-P, 2013, Journal of epidemiology and community health, 67, 1-4. A1 Journal article (refereed), original research -
Serum Omega-3 Polyunsaturated Fatty Acids and Risk of Incident Type 2 Diabetes in Men: The Kuopio Ischaemic Heart Disease Risk Factor Study
Virtanen JK, Mursu J, Voutilainen S, Uusitupa M, Tuomainen T-P, 2013, Diabetes care, 37, 2, 189-196. A1 Journal article (refereed), original research -
Voi ja sydäninfarktiriski
Voutilainen S, Nurmi A, Virtanen J, Mursu J, Tuomainen T-P, 2013, Lääkärilehti, 68, 38, 2351-2357. A1 Journal article (refereed), original research -
Association of serum 25-hydroxyvitamin D with type 2 diabetes and markers of insulin resistance in a general older population in Finland
Hurskainen AR, Virtanen JK, Tuomainen T-P, Nurmi T, Voutilainen S, 2012, Diabetes/metabolism research and reviews, 28, 418-423. A1 Journal article (refereed), original research -
Association of serum n-3 polyunsaturated fatty acids with C-reactive protein in men
Reinders I, Virtanen JK, Brouwer IA, Tuomainen T-P, 2012, European journal of clinical nutrition, 66, 736-741. A1 Journal article (refereed), original research -
Dietary intake of polyunsaturated fatty acids and risk of hip fracture in men and women
Virtanen JK, Mozaffarian D, Willett WC, Feskanich D, 2012, Osteoporosis international, 23, 2615-2624. A1 Journal article (refereed), original research -
Dietary supplements and mortality
Tuomainen TP, Virtanen JK, Voutilainen S, 2012, Archives of internal medicine, 171, 18, 449-50. A1 Journal article (refereed), original research -
Myocardial infarction in relation to mercury and fatty acids from fish: a risk-benefit analysis based on pooled Finnish and Swedish data in men
Wennberg M, Strömberg U, Bergdahl IA, Jansson J-H, Kauhanen J, Norberg M, Salonen JT, Skerfving S, Tuomainen T-P, Vessby B, Virtanen JK, 2012, American journal of clinical nutrition, 96, 706-713. A1 Journal article (refereed), original research -
Regular consumption of eggs does not affect carotid plaque area or risk of acute myocardial infarction in Finnish men
Voutilainen S, Nurmi A, Mursu J, Tuomainen T-P, Ruusunen A, Virtanen JK, 2012, Atherosclerosis, 227, 1, 186-188. A1 Journal article (refereed), original research -
Serum long-chain n-3 polyunsaturated fatty acids, mercury, and risk of sudden cardiac death in men: a prospective population-based study
Virtanen JK, Laukkanen JA, Mursu J, Voutilainen S, Tuomainen TP, 2012, PLoS ONE, 7, 7, 1046. A1 Journal article (refereed), original research -
Serum long-chain n-3 polyunsaturated fatty acids, methylmercury and blood pressure in an older population
Virtanen JK, Nyantika AN, Kauhanen J, Voutilainen S, Tuomainen TP, 2012, Hypertension research, 35, 10, 1000-1004. A1 Journal article (refereed), original research -
Association of serum 25-hydroxyvitamin D with the risk of death in a general older population in Finland
Virtanen JK, Nurmi T, Voutilainen S, Mursu J & Tuomainen TP, 2011, European journal of nutrition, 50, 305-312. A1 Journal article (refereed), original research -
Evaluation of the cardiovascular effects of methylmercury exposures: current evidence supports development of a dose-response function for regulatory benefits analysis
Roman HA, Walsh TL, Coull BA, Dewailly É, Guallar E, Hattis D, Mariën K, Schwartz J, Stern AH, Virtanen JK, Rice G, 2011, Environmental health perspectives, 119, 5, 607-14. A2 Review article, Literature review, Systematic review -
Glycemic index, glycemic load, and the risk of acute myocardial infarction in Finnish men: the Kuopio Ischaemic Heart Disease Risk Factor Study
Mursu J, Virtanen JK, Rissanen TH, Tuomainen TP, Nykänen I, Laukkanen JA, Kortelainen R & Voutilainen S., 2011, Nutrition metabolism and cardiovascular diseases, 21, 144-149. A1 Journal article (refereed), original research -
Serum polyunsaturated fatty acids are not associated with the risk of severe depression in middle-aged Finnish men: Kuopio Ischaemic Heart Disease Risk Factor (KIHD) Study.
Ruusunen A, Virtanen JK, Lehto SM, Tolmunen T, Kauhanen J, Voutilainen S., 2011, European journal of nutrition, 50, 89-96. A1 Journal article (refereed), original research -
Serum long-chain n-3 polyunsaturated fatty acids and risk of hospital diagnosis of atrial fibrillation in men
Virtanen JK, Mursu J, Voutilainen S, Tuomainen T-P, 2009, Circulation, 120, 2315-2321. A1 Journal article (refereed), original research -
Fish consumption and risk of major chronic disease in men
Virtanen JK, Mozaffarian D, Chiuve E, Rimm EB, 2008, American journal of clinical nutrition, 88, 1618-1625. A1 Journal article (refereed), original research -
Fish consumption and risk of subclinical brain abnormalities on MRI in older adults
Virtanen JK, Siscovick DS, Longstreth Jr WT, Kuller LH, Mozaffarian D, 2008, Neurology, 71, 439-446. A1 Journal article (refereed), original research -
Functional COMT Val158Met polymorphism, risk of acute coronary events and serum homocysteine: the Kuopio Ischaemic Heart Disease Risk Factor Study
Voutilainen S, Tuomainen TP, Korhonen M, Mursu J, Virtanen JK, Happonen P, Alftan G, Erlund I, North KE, Mosher MJ, Kauhanen J, Tiihonen J, Kaplan GA, Salonen JT, 2007, PLoS ONE, 2, 1, e181. A1 Journal article (refereed), original research -
Mercury as a risk factor for cardiovascular diseases
Virtanen JK, Rissanen TH, Voutilainen S, Tuomainen T-P, 2007, Journal of nutritional biochemistry, 18, 75-85. A1 Journal article (refereed), original research -
High dietary methionine intake increases the risk of acute coronary events in middle-aged men
Virtanen JK, Voutilainen S, Rissanen TH, Happonen P, Mursu J, Laukkanen JA, Poulsen H, Lakka TA, Salonen JT, 2006, Nutrition metabolism and cardiovascular diseases, 16, 113-120. A1 Journal article (refereed), original research -
Homocysteine, Folate and Cardiovascular Diseases
Virtanen JK, 2005, Kuopio University Publications D. Medical Sciences. G5 Doctoral dissertation (article) -
Mercury, fish oils, and risk of acute coronary events and cardiovascular disease, coronary heart disease, and all-cause mortality in men in Eastern Finland
Virtanen JK, Voutilainen S, Rissanen TH, Mursu J, Tuomainen T-P, Korhonen MJ, Valkonen V-P, Seppänen K, Laukkanen JA, Salonen JT, 2005, Arteriosclerosis, thrombosis, and vascular biology, 25, 228-233. A1 Journal article (refereed), original research -
Serum homocysteine, folate and risk of stroke: Kuopio ischaemic heart disease risk factor (KIHD) study
Virtanen JK, Voutilainen S, Happonen P, Alfthan G, Kaikkonen J, Mursu J, Rissanen TH, Kaplan GA, Korhonen MJ, Sivenius J, Salonen JT, 2005, EUROPEAN JOURNAL OF CARDIOVASCULAR PREVENTION AND REHABILITATION, 12, 369-375. A1 Journal article (refereed), original research -
The effects of coffee consumption on lipid peroxidation and plasma total homocysteine concentrations: a clinical trial
Mursu J, Voutilainen S, Nurmi T, Alfthan G, Virtanen JK, Rissanen TH, Happonen P, Nyyssönen K, Kaikkonen J, Salonen R, Salonen JT, 2005, Free radical biology and medicine, 38, 527-534. A1 Journal article (refereed), original research -
Serum folate and homocysteine and the incidence of acute coronary events: the Kuopio Ischaemic Heart Disease Risk Factor Study
Voutilainen S, Virtanen JK, Rissanen TH, Alfthan G, Laukkanen J, Nyyssönen K, Mursu J, Valkonen V-P, Tuomainen T-P, Kaplan GA, Salonen JT, 2004, American journal of clinical nutrition, 80, 317-23. A1 Journal article (refereed), original research -
Folic acid supplementation increases serum paraoxonase activity: evidence from a randomized double blind oral supplementarion trial in men
Voutilainen S, Rissanen TH, Virtanen JK, Porkkala-Sarataho E, Kaikkonen J, Seppänen K, Tuomainen T-P, Lehtimäki T, Rontu R, Hämelahti P, Penttilä I, Mursu J, Salonen JT, 2003, Current topics in nutraceutical research, 1, 3, 175-182. A1 Journal article (refereed), original research