Leila Karhunen
University Lecturer
Institute of Public Health and Clinical Nutrition, School of Medicine, Faculty of Health Sciences
leila.karhunen@uef.fi | +358 40 355 2776
Research groups
Publications
130/130 items-
Associations of Lifestyle Patterns with Glucose and Lipid Metabolism in Finnish Adults at Increased Risk of Type 2 Diabetes
Manninen, Suvi; Tilles‐Tirkkonen, Tanja; Aittola, Kirsikka; Männikkö, Reija; Karhunen, Leila; Kolehmainen, Marjukka; Schwab, Ursula; Lindström, Jaana; Lakka, Timo; Pihlajamäki, Jussi; the Stop Diabetes study group. 2024. Molecular nutrition and food research. [Epub ahead of print 2 Feb 2024]: 1-12 -
Effectiveness of workplace choice architecture modification for healthy eating and daily physical activity
Rantala, Eeva; Vanhatalo, Saara; Valtanen, Mikko; Lindström, Jaana; Pihlajamäki, Jussi; Poutanen, Kaisa; Absetz, Pilvikki; Karhunen, Leila. 2024. Bmc public health. 24: . 939 -
Acceptability of workplace choice architecture modification for healthy behaviours
Rantala, Eeva; Vanhatalo, Saara; Perez-Cueto, Federico J A; Pihlajamäki, Jussi; Poutanen, Kaisa; Karhunen, Leila; Absetz, Pilvikki. 2023. Bmc public health. 23: . 2451 -
Associations of low levels of air pollution with cardiometabolic outcomes and the role of diet quality in individuals with obesity
Healy, Darren R; Kårlund, Anna; Mikkonen, Santtu; Puhakka, Soile; Karhunen, Leila; Kolehmainen, Marjukka. 2023. Environmental research. 2024; 242: -
Eating behavior dimensions and 9-year weight loss maintenance: a sub-study of the Finnish Diabetes prevention study
Salmela, Jutta; Konttinen, Hanna; Lappalainen, Raimo; Muotka, Joona; Antikainen, Anne; Lindström, Jaana; Tuomilehto, Jaakko; Uusitupa, Matti; Karhunen, Leila. 2023. International journal of obesity. 47: 564-573 -
Kokonaisvaltaista ruokakasvatusta varhaiskasvatukseen ja perusopetukseen - Loppuraportti 2023
Laitinen, Aija; Lindholm, Taru; Talvia, Sanna; Kettukangas, Titta; Kähkönen, Kaisa; Karhunen, Leila; Varjonen, Silja; Hyvönen, Aliisa; Paavola, Saila; Lyytikäinen, Katri; Sainio, Taina; Kuusisto, Anne. 2023. . . Itä-Suomen yliopisto -
Metabolic profiles reflect weight loss maintenance and the composition of diet after very-low-energy diet
Näätänen, Mari; Kårlund, Anna; Mikkonen, Santtu; Klåvus, Anton; Savolainen, Otto; Lehtonen, Marko; Karhunen, Leila; Hanhineva, Kati; Kolehmainen, Marjukka. 2023. Clinical nutrition. 42: 1126-1141 -
Associations between weight loss history and factors related to type 2 diabetes risk in the Stop Diabetes study
Halali, F; Lapveteläinen, A; Aittola, K; Männikkö, R; Tilles-Tirkkonen, T; Järvelä-Reijonen, E; Absetz, P; Kolehmainen, M; Schwab, U; Lindström, J; Lakka, TA; Pihlajamäki, J; Karhunen, L. 2022. International journal of obesity. 46: 935-942 -
Common Genetic Variation and Age of Onset of Anorexia Nervosa
Watson, Hunna J.; Thornton, Laura M.; Yilmaz, Zeynep; Baker, Jessica H.; Coleman, Jonathan R.I.; Adan, Roger A.H.; Alfredsson, Lars; Andreassen, Ole A.; Ask, Helga; Berrettini, Wade H.; Boehnke, Michael; Boehm, Ilka; Boni, Claudette; Buehren, Katharina; Bulant, Josef; Burghardt, Roland; Chang, Xiao; Cichon, Sven; Cone, Roger D.; Courtet, Philippe; Crow, Scott; Crowley, James J.; Danner, Unna N.; de Zwaan, Martina; Dedoussis, George; DeSocio, Janiece E.; Dick, Danielle M.; Dikeos, Dimitris; Dina,. 2022. Biological psychiatry global open science. 2: 368-378 -
Implementation of food education in school environments improves pupils’ eating patterns and social participation in school dining
Laitinen, Aija L; Antikainen, Amma; Mikkonen, Santtu; Kähkönen, Kaisa; Talvia, Sanna; Varjonen, Silja; Paavola, Saila; Karhunen, Leila; Tilles-Tirkkonen, Tanja. 2022. Public health nutrition. 25: 3548-3558 -
Psychometric evaluation of three-factor eating questionnaire -R18 in aging Finnish men with increased risk for type 2 diabetes
Malkki-Keinänen, Katriina; Lankinen, Maria; Karhunen, Leila; Schwab, Ursula. 2022. Nutrition and health. [First published 11 July 2022]: 1-12 -
Real-world effectiveness of digital and group-based lifestyle interventions as compared with usual care to reduce type 2 diabetes risk – A stop diabetes pragmatic randomised trial
Lakka, Timo A.; Aittola, Kirsikka; Järvelä-Reijonen, Elina; Tilles-Tirkkonen, Tanja; Männikkö, Reija; Lintu, Niina; Karhunen, Leila; Kolehmainen, Marjukka; Harjumaa, Marja; Mattila, Elina; Järvenpää, Riia; Ermes, Miikka; Mikkonen, Santtu; Martikainen, Janne; Poutanen, Kaisa; Schwab, Ursula; Absetz, Pilvikki; Lindström, Jaana; Pihlajamäki, Jussi. 2022. The Lancet regional health – Europe. 2023; 24: -
Ruokasuhde koulutuksen ja työn ulkopuolella olevilla nuorilla aikuisilla
Talvia, Sanna; Räsänen, Susanne; Helkkola, Lilian; Karhunen, Leila. 2022. Sosiaalilääketieteellinen aikakauslehti. 59: 153-168 -
Sensory Appeal and Routines Beat Health Messages and Visibility Enhancements: Mixed-Methods Analysis of a Choice-Architecture Intervention in a Workplace Cafeteria
Rantala, Eeva; Järvelä-Reijonen, Elina; Pettersson, Kati; Laine, Janne; Vartiainen, Paula; Närväinen, Johanna; Pihlajamäki, Jussi; Poutanen, Kaisa; Absetz, Pilvikki; Karhunen, Leila. 2022. Nutrients. 14: -
The ‘Tasty School’ model is feasible for food education in primary schools
Laitinen, Aija Liisa; Antikainen, Amma; Mikkonen, Santtu; Kähkönen, Kaisa; Talvia, Sanna; Varjonen, Silja; Paavola, Saila; Karhunen, Leila; Tilles‐Tirkkonen, Tanja. 2022. Journal of human nutrition and dietetics. 2023; 36: 75-85 -
Choice Architecture Cueing to Healthier Dietary Choices and Physical Activity at the Workplace: Implementation and Feasibility Evaluation
Rantala, Eeva; Vanhatalo, Saara; Tilles-Tirkkonen, Tanja; Kanerva, Markus; Hansen, Pelle Guldborg; Kolehmainen, Marjukka; Männikkö, Reija; Lindström, Jaana; Pihlajamäki, Jussi; Poutanen, Kaisa; Karhunen, Leila; Absetz, Pilvikki. 2021. Nutrients. 13: 3592 -
Enhanced Eating Competence Is Associated with Improved Diet Quality and Cardiometabolic Profile in Finnish Adults with Increased Risk of Type 2 Diabetes
Aittola, Kirsikka; Karhunen, Leila; Männikkö, Reija; Järvelä-Reijonen, Elina; Mikkonen, Santtu; Absetz, Pilvikki; Kolehmainen, Marjukka; Schwab, Ursula; Harjumaa, Marja; Lindström, Jaana; Lakka, Timo; Tilles-Tirkkonen, Tanja; Pihlajamäki, Jussi. 2021. Nutrients. 13: 4030 -
Food education in Finnish primary education - defining themes and learning objectives using the Delphi technique
Laitinen, Aija Liisa; Tilles-Tirkkonen, Tanja; Karhunen, Leila; Talvia, Sanna. 2021. British food journal. 123: 404-427 -
Formation and Validation of the Healthy Diet Index (HDI) for Evaluation of Diet Quality in Healthcare
Lindström, Jaana; Aittola, Kirsikka; Pölönen, Auli; Hemiö, Katri; Ahonen, Kirsti; Karhunen, Leila; Männikkö, Reija; Siljamäki-Ojansuu, Ulla; Tilles-Tirkkonen, Tanja; Virtanen, Eeva; Pihlajamäki, Jussi; Schwab, Ursula. 2021. International journal of environmental research and public health. 18: 2362 -
Maistuva koulu
Tilles-Tirkkonen, Tanja; Laitinen, Aija; Antikainen, Amma; Karhunen, Leila; Kähkönen, Kaisa; Varjonen, Silja; Paavola, Saila; Lyytikäinen, Katri; Hyvönen, Aliisa; Erkkola, Maijaliisa; Valve, Raisa. 2021. HYTE-toimintamalli. . Terveyden ja hyvinvoinnin laitos -
Ruokasuhteen pedagoginen viitekehys ruokakasvatuksen näkökulmana
Talvia, Sanna; Lindholm, Taru; Helkkola, Lilian; Karhunen, Leila; Räsänen, Susanne; Kinnunen, Heidi; Ollilainen, Katja; Anglé, Susanna. 2021. Ainedidaktiikka. 2021; 5: 71–89 -
Sleep-time physiological recovery is associated with eating habits in distressed working-age Finns with overweight: secondary analysis of a randomised controlled trial
Järvelä-Reijonen, Elina; Järvinen, Suvi; Karhunen, Leila; Föhr, Tiina; Myllymäki, Tero; Sairanen, Essi; Lindroos, Sanni; Peuhkuri, Katri; Hallikainen, Maarit; Pihlajamäki, Jussi; Puttonen, Sampsa; Korpela, Riitta; Ermes, Miikka; Lappalainen, Raimo; Kujala, Urho M; Kolehmainen, Marjukka; Laitinen, Jaana. 2021. Journal of occupational medicine and toxicology. 16: 23 -
Syömisen säätely
Karhunen, Leila. Teoksessa: Mutanen, Marja; Niinikoski, Harri; Schwab, Ursula; Uusitupa, Matti(toim.) , 2021. Ravitsemustiede (8. uud. painos). s. 88-93. Duodecim -
Syömisen säätely
Uusitupa, Matti; Karhunen, Leila. Teoksessa: Mutanen, Marja; Niinikoski, Harri; Schwab, Ursula; Uusitupa, Matti(toim.) , 2021. Ravitsemustiede (8. uud. painos). s. 404-405. Duodecim -
Anodal tDCS Over the Left Prefrontal Cortex Does Not Cause Clinically Significant Changes in Circulating Metabolites
Kortteenniemi, Aaron; Ortega-Alonso, Alfredo; Javadi, Amir-Homayoun; Tolmunen, Tommi; Ali-Sisto, Toni; Kotilainen, Tuukka; Wikgren, Jan; Karhunen, Leila; Velagapudi, Vidya; Lehto, Soili M. 2020. Frontiers in psychiatry. 11: 403 -
Eating behavior tendencies among Finnish adults in relation to previous weight loss attempts
Halali, Faranak; Lapveteläinen, Anja; Karhunen, Leila; Kantanen, Teuvo. 2020. Appetite. 150: 104650 -
Effect of metabolic state on implicit and explicit responses to food in young healthy females
Juvonen, K; Lapveteläinen, A; Närväinen, J; Absetz, P; Kantanen, T; Kolehmainen, M; Sinikallio, S; Pihlajamäki, J; Karhunen, L. 2020. Appetite. 148: 104593 -
Genetic identification of cell types underlying brain complex traits yields insights into the etiology of Parkinson's disease
Bryois, Julien; Skene, Nathan G; Folkmann Hansen, Thomas; Kogelman, Lisette JA; Watson, Hunna J; Liu; Eating Disorders Working Group of the Psychiatric Genomics Consortium; International Headache Genetics Consortium, 23andMe Research Team [Incl. Karhunen, Leila]. 2020. Nature genetics. 52: 482-493 -
Plasma lipid profile associates with the improvement of psychological well-being in individuals with perceived stress symptoms
Noerman, S; Klåvus, A; Järvelä-Reijonen, E; Karhunen, L; Auriola, S; Korpela, R; Lappalainen, R; Kujala, UM; Puttonen, S; Kolehmainen, M; Hanhineva, K. 2020. Scientific reports. 10: 2143 -
Post-weight loss changes in fasting appetite- and energy balance-related hormone concentrations and the effect of the macronutrient content of a weight maintenance diet: a randomised controlled trial
Näätänen, Mari; Kolehmainen, Marjukka; Laaksonen, David E; Herzig, Karl-Heinz; Poutanen, Kaisa; Karhunen, Leila. 2020. European journal of nutrition. 2021; 60: 2603-2616 -
Shared Genetic Risk Between Eating Disorder- And Substance-Use-Related Phenotypes: Evidence From Genome-Wide Association Studies
Munn-Chernoff, Melissa A; Johnson, Emma C; Chou, Yi-Ling; Coleman, Jonathan RI; Thornton, Laura M; Walters, Raymond K; Yilmaz, Zeynep; Baker, Jessica H; Hübel, Christopher; Gordon, Scott; Medland, Sarah E; Watson, Hunna J; Gaspar, Héléna A; Bryois, Julien; Hinney, Anke; Leppä, Virpi M; Mattheisen, Manuel; Ripke, Stephan; Yao, Shuyang; Giusti-Rodríguez, Paola et al. [incl. Karhunen, Leila]. 2020. Addiction biology. 2021; 26: e12880 -
The Effects of Acceptance and Commitment Therapy (ACT) Intervention on Inflammation and Stress Biomarkers: a Randomized Controlled Trial
Järvelä-Reijonen, Elina; Puttonen, Sampsa; Karhunen, Leila; Sairanen, Essi; Laitinen, Jaana; Kolehmainen, Mikko; Pihlajamäki, Jussi; Kujala, Urho M; Korpela, Riitta; Ermes, Miikka; Lappalainen, Raimo; Kolehmainen, Marjukka. 2020. International journal of behavioral medicine. 27: 539-555 -
Treatment interventions for Severe and Enduring Eating Disorders: Systematic review
Kotilahti, Emilia; West, Madeline; Isomaa, Rasmus; Karhunen, Leila; Rocks, Tetyana; Ruusunen, Anu. 2020. International journal of eating disorders. 53: 1280-1302 -
Associations Between Attention-Deficit/Hyperactivity Disorder and Various Eating Disorders: A Swedish Nationwide Population Study Using Multiple Genetically Informative Approaches
Yao, Shuyang; Kuja-Halkola, Ralf; Martin, Joanna; Lu, Yi; Lichtenstein, Paul; Norring, Claes; Birgegård, Andreas; Yilmaz, Zeynep; Hübel, Christopher; Watson, Hunna; Baker, Jessica; Almqvist, Catarina; Eating Disorders Working Group of the Psychiatric Genomics Consortium; Thornton, Laura M; Magnusson, Patrik K; Bulik, Cynthia M; Larsson, Henrik [incl. Karhunen, L]. 2019. Biological psychiatry. 86: 577-586 -
Digitally supported program for type 2 diabetes risk identification and risk reduction in real-world setting: protocol for the StopDia model and randomized controlled trial
Pihlajamäki, J; Männikkö, R; Tilles-Tirkkonen, T; Karhunen, L; Kolehmainen, M; Schwab, U; Lintu, N; Paananen, J; Järvenpää, R; Harjumaa, M; Martikainen, J; Kohl, J; Poutanen, K; Ermes, M; Absetz, P; Lindström, J; Lakka, TA. 2019. Bmc public health. 19: 255 -
Eating Competence Is Associated with Lower Prevalence of Obesity and Better Insulin Sensitivity in Finnish Adults with Increased Risk for Type 2 Diabetes: The StopDia Study
Tilles-Tirkkonen, Tanja; Aittola, Kirsikka; Männikkö, Reija; Absetz, Pilvikki; Kolehmainen, Marjukka; Schwab, Ursula; Lindström, Jaana; Lakka, Timo; Pihlajamäki, Jussi; Karhunen, Leila. 2019. Nutrients. 2020; 12: 104 -
Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa
Watson, HJ; Yilmaz, Z; Thornton, LM; Hübel, C; Coleman, JRI; Gaspar, HA; Bryois, J; Hinney, A; Leppä, VM; Mattheisen, M; Medland, SE; Ripke, S; Yao, S; Giusti-Rodríguez, P; Hanscombe, KB; Purves, KL; Adan, RAH; Alfredsson, L; Ando, T; Andreassen, OA; Anorexia Nervosa Genetics Initiative; Eating Disorders Working Group of the Psychiatric Genomics Consortium et al. (incl. Karhunen, Leila). 2019. Nature genetics. 51: 1207-1214 -
Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders
Lee, Phil H; Anttila, Verneri; Won, Hyejung; Feng, Yen-Chen A; Rosenthal, Jacob; Zhu, Zhaozhong; Tucker-Drob, Elliot M; Nivard, Michel G; Grotzinger, Andrew D; Posthuma, Danielle; Wang, Meg M-J; Yu, Dongmei; Stahl, Eli A; Walters, Raymond K; Anney, Richard JL; Duncan, Laramie E; Ge, Tian; Adolfsson, Rolf; Banaschewski, Tobias; Belangero Sintia; et al. for the Cross-Disorder Group of the Psychiatric Genomics Consortium [incl. Karhunen, Leila]. 2019. Cell. 179: 1469-1482.e11 -
Metabolic state as a modulator of neural event-related potentials for food stimuli in an implicit association test
Lahtinen, Aapeli; Juvonen, Kristiina; Lapveteläinen, Anja; Kolehmainen, Marjukka; Lindholm, Mikko; Tanila, Heikki; Kantanen, Teuvo; Sinikallio, Sanna; Karhunen, Leila; Närväinen, Johanna. 2019. Physiology and behavior. 209: 112589 -
Mobile Phone App for Self-Monitoring of Eating Rhythm: Field Experiment
Pentikäinen, S; Tanner, H; Karhunen, L; Kolehmainen, M; Poutanen, K; Pennanen, K. 2019. JMIR mhealth and uhealth. 7: e11490 -
Tuuppaamalla terveyttä: vihjeet vaikuttavat valintoihin
Kolehmainen, Marjukka; Poutanen, Kaisa; Absetz, Pilvikki; Karhunen, Leila. 2019. Lääkärilehti. 74: 811-815 -
A cross-sectional study of motivators and barriers of weight management among Finnish adult population
Halali F, Lapveteläinen A, Karhunen L, Saarela A-M, Lappalainen R, Kantanen T. 2018. Obesity facts -
Measured energy content of frequently purchased restaurant meals: multi-country cross sectional study
Roberts, SB; Das, SK; Suen, VMM; Pihlajamäki, J; Kuriyan, R; Steiner-Asiedu, M; Taetzsch, A; Anderson, AK; Silver, RE; Barger, K; Krauss, A; Karhunen, L; Zhang, X; Hambly, C; Schwab, U; Triffoni-Melo, AT; Taylor, SF; Economos, C; Kurpad, AV; Speakman, JR. 2018. BMJ. 363: k4864 -
Motivators, barriers and strategies of weight management: A cross-sectional study among Finnish adults
Halali, Faranak; Lapveteläinen, Anja; Karhunen, Leila; Saarela, Anne-Maria; Lappalainen, Raimo; Kantanen, Teuvo. 2018. Eating behaviors. 31: 80-87 -
Sosioekonomisesti heikommassa asemassa olevien kiinnostus ja mahdollisuudet digitaalisten terveyspalveluiden käyttöön
Tilles-Tirkkonen, Tanja; Lappi, Jenni; Karhunen, Leila; Harjumaa, Marja; Absetz, Pilvikki; Pihlajamäki, Jussi. 2018. Yhteiskuntapolitiikka. 83: 317-323 -
The effects of acceptance and commitment therapy on eating behavior and diet delivered through face-to-face contact and a mobile app: a randomized controlled trial
Järvelä-Reijonen, Elina; Karhunen, Leila; Sairanen, Essi; Muotka, Joona; Lindroos, Sanni; Laitinen, Jaana; Puttonen, Sampsa; Peuhkuri, Katri; Hallikainen, Maarit; Pihlajamäki, Jussi; Korpela, Riitta; Ermes, Miikka; Lappalainen, Raimo; Kolehmainen, Marjukka. 2018. International journal of behavioral nutrition and physical activity. 15: 22 -
Theory-informed nutrition education curriculum Tools For Feeling Good promotes healthy eating patterns among fifth grade pupils: cross-sectional study
Tilles-Tirkkonen, T; Nuutinen, O; Sinikallio, S; Poutanen, K; Karhunen, L. 2018. Journal of human nutrition and dietetics. 31: 647-657 -
A genome-wide association study of anorexia nervosa suggests a risk locus implicated in dysregulated leptin signaling
Li D, Chang X, Connolly JJ, Tian L, Liu Y, Bhoj EJ, Robinson N, Abrams D, Li YR, Bradfield JP, Kim CE, Li J, Wang F, Snyder J, Lemma M, Hou C, Wei Z, Guo Y, Qiu H, Mentch FD et al.. 2017. Scientific reports. : 847 -
Easy-going, rational, susceptible and struggling eaters: A segmentation study based on eating behaviour tendencies
Pentikäinen Saara, Arvola Anne, Karhunen Leila, Pennanen Kyösti. 2017. Appetite. 120: 212-221 -
Eating behaviour is associated with eating frequency and food consumption in 6-8 year-old children: The Physical Activity and Nutrition in Children (PANIC) study
Jalkanen H, Lindi V, Schwab U, Kiiskinen S, Venäläinen T, Karhunen L, Lakka TA, Eloranta AM. 2017. Appetite. 114: 28-37 -
Exploration of large, rare copy number variants associated with psychiatric and neurodevelopmental disorders in individuals with anorexia nervosa
Yilmaz Z, Szatkiewicz JP, Crowley JJ, Ancalade N, Brandys MK, van Elburg A, de Kovel CGF, Adan RAH, Hinney A, Hebebrand J, Gratacos M, Fernandez-Aranda F, Escaramis G, Gonzalez JR, Estivill X, Zeggini E, Sullivan PF, Bulik CM. 2017. Psychiatric genetics. 27: 152-158 -
Psychological flexibility mediates change in intuitive eating regulation in acceptance and commitment therapy interventions
Sairanen E, Tolvanen A, Karhunen L, Kolehmainen M, Järvelä-Reijonen E, Lindroos S, Peuhkuri K, Korpela R, Ermes M, Mattila E, Lappalainen R. 2017. Public health nutrition. 20: 1681-1691 -
Significant Locus and Metabolic Genetic Correlations Revealed in Genome-Wide Association Study of Anorexia Nervosa
Duncan L, Yilmaz Z, Gaspar H, Walters R, Goldstein J, Anttila V, Bulik-Sullivan B, Ripke S, Thornton L, Hinney A, Daly M, Sullivan PF, Zeggini E, Breen G, Bulik CM, Eating Disorders Working Group of the Psychiatric Genomics Consortium (incl. Karhunen L). 2017. American journal of psychiatry. [Epub ahead of print 12 May 2017]: 1-9 -
Development and preliminary validation of a Finnish version of the Eating Disorder Examination Questionnaire (EDE-Q)
Isomaa Rasmus, Lukkarila Ida-Lina, Ollila Teresa, Nenonen Helena, Charpentier Pia, Sinikallio Sanna, Karhunen Leila. 2016. Nordic journal of psychiatry. 70: 542-546 -
Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index
Hinney A, Kesselmeier M, Jall S, Volckmar AL, Föcker M, Antel J, Heid IM, Winkler TW, Grant SF, Guo Y, Bergen AW, Kaye W, Berrettini W, Hakonarson H, Herpertz-Dahlmann B, de Zwaan M, Herzog W, Ehrlich S, Zipfel S, Egberts KM et al., GCAN, WTCCC3, EGG, GIANT, Price Foundation Collaborative Group, Children's Hospital of Philadelphia/Price Foundation. 2016. Molecular psychiatry. 2017; 22: 192-201 -
Heart rate reactivity associated to positive and negative food and non-food visual stimuli
Kuoppa P, Tarvainen MP, Karhunen L, Närväinen J. Teoksessa: -(toim.) , 2016. Proceedings of the 38th Annual International Conference of the IEEE Engineering in Medicine and Biology. s. 5279-5282. IEEE -
High perceived stress is associated with unfavorable eating behavior in overweight and obese Finns of working age
Järvelä-Reijonen E, Karhunen L, Sairanen E, Rantala S, Laitinen J, Puttonen S, Peuhkuri K, Hallikainen M, Juvonen K, Myllymäki T, Föhr T, Pihlajamäki J, Korpela R, Ermes M, Lappalainen R, Kolehmainen M. 2016. Appetite. 103: 249-258 -
Psychophysiological responses to positive and negative food and nonfood visual stimuli
Kuoppa Pekka, Pulkkinen Kaisa, Tarvainen Mika P, Lankinen Maria, Lapveteläinen Anja, Sinikallio Sanna, Karhunen Leila, Karjalainen Pasi A, Kolehmainen Marjukka, Sallinen Janne, Närväinen Johanna. 2016. Journal of neuroscience, psychology, and economics. 9: 78-88 -
Regulation of alternative splicing in human obesity loci
Kaminska Dorota, Käkelä Pirjo, Nikkola Elina, Venesmaa Sari, Ilves Imre, Herzig Karl-Heinz, Kolehmainen Marjukka, Karhunen Leila, Kuusisto Johanna, Gylling Helena, Pajukanta Päivi, Laakso Markku, Pihlajamäki Jussi. 2016. Obesity. 24: 2033-2037 -
Usage and Dose Response of a Mobile Acceptance and Commitment Therapy App: Secondary Analysis of the Intervention Arm of a Randomized Controlled Trial
Mattila E, Lappalainen R, Välkkynen P, Sairanen E, Lappalainen P, Karhunen L, Peuhkuri K, Korpela R, Kolehmainen M, Ermes M. 2016. JMIR mhealth and uhealth. 4: e90 -
Cross-linking of sodium caseinate-structured emulsion with transglutaminase alters postprandial metabolic and appetite responses in healthy young individuals
Juvonen Kristiina R, Macierzanka Adam, Lille Martina E, Laaksonen David E, Mykkänen Hannu M, Niskanen Leo K, Pihlajamäki Jussi, Mäkelä Kari A, Mills Clare EN, Mackie Alan R, Malcolm Paul, Herzig Karl-Heinz, Poutanen Kaisa S, Karhunen Leila J. 2015. British journal of nutrition. 114: 418-429 -
Lifestyle intervention has a beneficial effect on eating behavior and long-term weight loss in obese adults
Nurkkala Marjukka, Kaikkonen Kaisu, Vanhala Marja L, Karhunen Leila, Keränen Anna-Maria, Korpelainen Raija. 2015. Eating behaviors. 18: 179-185 -
Predictors of increase in physical activity during a 6-month follow-up period among overweight, physically inactive healthy young adults
Mutikainen Sara, Föhr (Teisala) T, Karhunen Leila, Kolehmainen Marjukka, Kainulainen Heikki, Lappalainen Raimo, Kujala Urho M. 2015. Journal of exercise science and fitness. 13: 63-71 -
Preliminary Finnish Measures of Eating Competence Suggest Association with Health-Promoting Eating Patterns and Related Psychobehavioral Factors in 10-17 Year Old Adolescents
Tilles-Tirkkonen Tanja, Nuutinen Outi, Suominen Sakari, Liukkonen Jarmo, Poutanen Kaisa, Karhunen Leila. 2015. Nutrients. 7: 3828-3846 -
Psychological Flexibility and Mindfulness Explain Intuitive Eating in Overweight Adults
Sairanen Essi, Tolvanen Asko, Karhunen Leila, Kolehmainen Marjukka, Järvelä Elina, Rantala Sanni, Peuhkuri Katri, Korpela Riitta, Lappalainen Raimo. 2015. Behavior modification. 39: 557-559 -
A genome-wide association study of anorexia nervosa
Boraska V, Franklin CS, Floyd JAB, Thornton LM, Huckins LM, Southam L, Rayner NW, Tachmazidou I, Klump KL, Treasure J, Lewis CM, Schmidt U, Tozzi F, Kiezebrink K, Hebebrand J, Gorwood P, Adan RAH, Kas MJH, Favaro A, Santonastaso P et.al. 2014. Molecular psychiatry. 19: 1085-1094 -
Determinants of a regular intake of a nutritionally balanced school lunch among 10-17-year-old schoolchildren with special reference to sense of coherence
Tilles-Tirkkonen T, Suominen S, Liukkonen J, Poutanen K, Karhunen L. 2014. Journal of human nutrition and dietetics. Epub ahead of print: - -
Enrichment of biscuits and juice with oat ß-glucan enhances postprandial satiety
Pentikäinen Saara, Karhunen Leila, Flander Laura, Katina Kati, Meynier Alexandra, Aymard Pierre, Vinoy Sophie, Poutanen Kaisa. 2014. Appetite. 75: 150-156 -
Flexibility in weight management
Sairanen Essi, Lappalainen Raimo, Lapveteläinen Anja, Tolvanen Asko, Karhunen Leila. 2014. Eating behaviors. 15: 218-224 -
The effectiveness and applicability of different lifestyle interventions for enhancing wellbeing: the study design for a randomized controlled trial for persons with metabolic syndrome risk factors and psychological distress
Lappalainen Raimo, Sairanen Essi, Järvelä Elina, Rantala Sanni, Korpela Riitta, Puttonen Sampsa, Kujala Urho M, Myllymäki Tero, Peuhkuri Katri, Mattila Elina, Kaipainen Kirsikka, Ahtinen Aino, Karhunen Leila, Pihlajamäki Jussi, Järnefelt Heli, Laitinen Jaana, Kutinlahti Eija, Saarelma Osmo, Ermes Miikka, Kolehmainen Marjukka. 2014. Bmc public health. 14: - -
Using ancestry-informative markers to identify fine structure across 15 populations of European origin
Huckins Laura M, Boraska Vesna, Franklin Christopher S, FloydJames AB, Southam Lorraine, GCAN, WTCCC3, Sullivan Patrick F, Bulik Cynthia M, Collier David A, Tyler-Smith Chris, Zeggini Eleftheria, Tachmazidou Ioanna. 2014. European journal of human genetics. 22: 1190-1200 -
Adipose tissue INSR splicing in humans associates with fasting insulin level and is regulated by weight loss
Kaminska D, Hämäläinen M, Cederberg H, Käkelä P, Venesmaa S, Miettinen P, Ilves I, Herzig KH, Kolehmainen M, Karhunen L, Kuusisto J, Gylling H, Laakso M, Pihlajamäki J. 2013. Diabetologia. Epub 2013 Nov 7.: 1-5 -
Increased sensitivity to food cues in the fasted state and decreased inhibitory control in the satiated state in the overweight
Martens MJI, Born JM, Lemmens SGT, Karhunen L, Heinecke A, Goebel R, Adam TC, Westerterp-Plantenga MS. 2013. American journal of clinical nutrition. 97: 471-479 -
Influence of serotonin transporter gene polymorphism (5-HTTLPR polymorphism) on the relation between brain 5-HT transporter binding and heart rate corrected cardiac repolarization interval
Kauppila E, Vanninen E, Kaurijoki S, Karhunen L, Pietiläinen KH, Rissanen A, Tiihonen J, Pesonen U, Kaprio J. 2013. PLoS ONE. 8: e50303 -
Association of the fat mass and obesity-associated (FTO) gene variant (rs9939609) with dietary intake in the Finnish Diabetes Prevention Study
Lappalainen Tiina, Lindström Jaana, Paananen Jussi, Eriksson Johan G, Karhunen Leila, Tuomilehto Jaakko, Uusitupa Matti for the Finnish Diabetes Prevention Study Group. 2012. British journal of nutrition. 108: 1859-65 -
Crosslinking with transglutaminase does not change matabolic effects of sodium caseinate in model beverage in healthy young individuals
Juvonen KR, Lille ME, Laaksonen DE, Mykkänen HM, Niskanen LK, Herzig K-H, Poutanen KS, Karhunen LJ. 2012. Nutrition journal. 11: - -
Genome-wide association analysis of eating disorder-related symptoms, behaviors, and personality traits
Boraska V, Davis OSP, Cherkas LF, Helder SG, Harris J, Krug I, Liao TP-C, Treasure J, Ntalla I, Karhunen L, Keski-Rahkonen A, Christakopoulou D, Raevuori A, Shin S-Y, Dedoussis GV, Kaprio J, Soranzo N, Spector TD, Collier DA, Zeggini E. 2012. American journal of medical genetics. Part B : neuropsychiatric genetics. 159B: 803-811 -
How does lifestyle intervention affect depressive symptoms? Results from the Finnish Diabetes Prevention Study
Ruusunen A, Voutilainen S, Karhunen L, Lehto S. M., Tolmunen T, Keinänen-Kiukaanniemi S, Eriksson J, Tuomilehto J, Uusitupa M and Lindström J. 2012. Diabetic medicine. 29: e126-32 -
Painonhallinta ostoskeskusasiakkaan näkökulmasta
Lapveteläinen A, Karhunen L, Tammela L, Riekkinen K, Poutanen K, Kananen T.. Teoksessa: Kantanen T, Lapveteläinen A(toim.) , 2012. Kuluttajat painonhallinnan markkinoilla. s. 19-23. Itä-Suomen Yliopisto -
Perceptions, motives, and psychological flexibility associated with weight management
Sairanen E, Lappalainen R, Lapveteläinen A, Karhunen L. 2012. Journal of obesity & weight loss therapy. 2: 1 -
Psychobehavioural Factors Are More Strongly Associated with Successful Weight Management Than Predetermined Satiety Effect or Other Characteristics of Diet
Karhunen L, Lyly M, Lapveteläinen A, Kolehmainen M, Laaksonen DE, Lähteenmäki L, Poutanen K. 2012. Journal of obesity. 2012: - -
Syömisen säätely
Ukkola O, Karhunen L. Teoksessa: Aro A, Mutanen M, Uusitupa M(toim.) , 2012. Ravitsemustiede. s. 19-24. Duodecim -
Tuotetietoihin liittyvät painonhallintakäsitykset
Lapveteläinen A, Pulkkinen K, KarhunenL, Kantanen T. Teoksessa: Kantanen T, Lapveteläinen A(toim.) , 2012. Kuluttajat painonhallinnan markkinoilla. s. 25-30. Itä-Suomen Yliopisto -
Structure modification of a milk protein-based model food affects postprandial intestinal peptide release and fullness in healthy young men
Juvonen Kristiina R, Karhunen Leila J, Vuori Elisa, Lille Martina E, Karhu Toni, Jurado-Acosta Alicia, Laaksonen David E, Mykkänen Hannu M, Niskanen Leo K, Poutanen Kaisa S, Herzig Karl-heinz. 2011. British journal of nutrition. 106: 1890-1898 -
The quality of school lunch consumed reflects overall eating patterns in 11-16-year-old schoolchildren in Finland
Tilles-Tirkkonen Tanja, Pentikäinen Saara, Lappi Jenni, Karhunen Leila, Poutanen Kaisa, Mykkänen Hannu. 2011. Public health nutrition. 14: 2092-2098 -
A psyllium fiber-enriched meal strongly attenuates postprandial gastrointestinal peptide release in healthy young adults
Karhunen LJ, Juvonen KR, Flander SM, Liukkonen K-H, Lähteenmäki L, Siloaho M, Laaksonen DE, Hetzig K-H, Uusitupa MI & Poutanen KS. 2010. Journal of nutrition. 140: 737-744 -
Brain electrical activity during food presentation in obese binge-eating women
Tammela LI , Pääkkönen A, Karhunen LJ, Karhu J, Uusitupa MIJ & Kuikka JT. 2010. Clinical physiology and functional imaging. 30: 135-140 -
Rye, oats, and weight management
Poutanen K, Lyly M, Juvonen K & Karhunen L. 2010. Cereal foods world. 55: 66-69 -
Semisolid meal enriched in oat bran decreases plasma glucose and insulin levels, but does not change gastrointestinal peptide responses or short-term appetite in healthy subjects
Juvonen K, Salmenkallio-Marttila M, Lyly M, Liukkonen KH, Lähteenmäki L, Laaksonen D, Uusitupa M, Herzig K, Poutanen K & Karhunen L. 2010. Nutrition metabolism and cardiovascular diseases. 21/2011: 2011/748-756 -
The effect of fibre amount, energy level and viscosity of beverages containing oat fibre supplement on perceived satiety
Lyly M, Ohls N, Lähteenmäki L, Salmenkallio-Marttila M, Liukkonen KH, Karhunen L, Poutanen K.. 2010. Food and nutrition research. 54: 2149 -
Cardiac repolarization and striatal dopamine transporter function are interrelated
Kauppila E, Vanninen E, Kuusela T, Kaurijoki S, Karhunen L, Pietiläinen KH, Rissanen A, Kaprio J, Tiihonen J, Kuikka J, Kaurijoki S, Karhunen L. 2009. Nuclear medicine communications. 30: 713-717 -
Effect of diet-induced weight loss on plasma apelin and cytokine levels in individuals with the metabolic syndrome
Heinonen MV, Laaksonen DE, Karhu T, Karhunen L, Laitinen T, Kainulainen S, Rissanen A, Niskanen L, Herzig KH. 2009. Nutrition metabolism and cardiovascular diseases. 19: 626-633 -
Fibre in beverages can enchance perceived satiety
Lyly M, Liukkonen K-H, Salmenkallio-Marttila M, Karhunen L, Poutanen K, Lähteenmäki L, Karhunen L, Poutanen K. 2009. European journal of nutrition. 48: 251-258 -
Foods for increasing satiety
Lyly M, Due A, Gunnarsdottir I, Karhunen L, Karhunen L. 2009. Agro food industry hi-tech. 20: 42-45 -
Geta heilsufullyröingar á matvaelaumbúöum byggt á vísindalega staöreyndum grunni?
Gunnarsdóttir I, Due A, Karhunen L, Lyly M, Karhunen L. 2009. LAEKNABLADID. 95: 195-200 -
Kan anprisning af fødevarer gøre os mere mætte?
Due A, Lyly M, Gunnarsdottir I, Karhunen L, Karhunen L. 2009. DIAETISTEN. 99: 15-17 -
Ruoansulatuskanavan peptidit kylläisyyden säätelyssä - miten ravinto vaikuttaa?
Juvonen KR, Purhonen A-K, Karhunen LJ, Hertzig K-H, Poutanen KS, Juvonen KR, Karhunen LJ, Poutanen KS. 2009. Duodecim. 125: 2067-2074 -
Viscosity of oat bran-enriched beverages influences gastrointestinal hormonal responses in healthy humans1-3
Juvonen KR, Purhonen A-K, Salmenkallio-Marttila M, Lähteenmäki L, Laaksonen DE, Herzig K-H, Uusitupa MIJ, Poutanen KS, Karhunen LJ, Juvonen KR, Uusitupa MIJ, Poutanen KS. 2009. Journal of nutrition. 139: 461-466 -
Association of serotonin transporter promoter regulatory region polymorphism and cerebral activity to visual presentation of food
Kaurijoki S, Kuikka JT, Niskanen E, Carlson S, Pietiläinen KH, Pesonen U, Kaprio JM, Rissanen A, Tiihonen J, Karhunen L, Karhunen L. 2008. Clinical physiology and functional imaging. 28: 270-276 -
Effect of protein, fat, carbohydrate and fibre on gastrointestinal peptide release in humans
Karhunen LJ, Juvonen KR, Huotari A, Purhonen AK, Herzig KH. 2008. Regulatory peptides. 149: 70-78 -
Neuroendocrinological regulation of food intake
Karhunen L, Herzig K-H, Karhunen L. 2008. Regulatory peptides -
Serotonin transporter binding and acquired obesity - An imaging study of monozygotic twin pairs
Koskela AK, Kaurijoki S, Pietiläinen KH, Karhunen L, Pesonen U, Kuikka JT, Kaprio J, Rissanen A. 2008. Physiology and behavior. 93: 724-732 -
Effect of dietary fibre and protein on postprandial satiety and satiety peptides
Juvonen KR, Flander SM, Karhunen LJ, Juvonen KR, Flander SM, Karhunen LJ. 2007. Agro food industry hi-tech. 18: [3 p.] -
Plasma ghrelin levels after two high-carbohydrate meals producing different insulin responses in patients with metabolic syndrome
Heinonen MV, Karhunen LJ, Chabot ED, Toppinen LK, Juntunen KS, Laaksonen DE, Siloaho M, Liukkonen K-H, Herzig K-H, Niskanen LK, Mykkänen HM. 2007. Regulatory peptides. 138: 118-125 -
Ruokahalun ja kylläisyyden säätely
Karhunen L, Mustajoki P. Teoksessa: Mustajoki P. Fogelholm M, Rissanen A, Uusitupa M(toim.) , 2006. Lihavuus. Ongelma ja hoito. 3. uud. p.. s. 100-118. Duodecim -
Aistien toiminta ja aistihavaintojen luokitukset
Karhunen L, Tuorila H, Karhunen L. Teoksessa: Tuorila H, Appelbye U(toim.) , 2005. Elintarvikkeiden aistinvaraiset tutkimusmenetelmät. s. 33-54. Yliopistopaino -
Kuitu ja proteiini tekevät kylläisemmäksi
Karhunen L, Liukkonen K-H, Karhunen L. 2005. Kehittyvä Elintarvike. : 37 -
Elintarvikkeet, kylläisyys ja painonhallinta
Liukkonen K-H, Kauppinen S, Karppinen S, Karhunen L, Autio K, Lähteenmäki L, Kauppinen S, Karhunen L. 2004. VTT-Tiedotteita. . VTT, Biotekniikka -
Aivojen kuvantaminen syömishäiriöiden ja lihavuuden tutkimuksessa
Karhunen L, Kuikka JT, Uusitupa M. 2003. Duodecim. 119: 859-865 -
Genetics of Obesity. Satellite Meeting of the 12th European Congress on Obesity
Karhunen L, Pihlajamäki J. 2003. Kuopio University Publications D. Medical Sciences. . - -
Treatment improves serotonin transporter binding and reduces binge eating
Tammela LI, Rissanen A, Kuikka JT, Karhunen LJ, Bergström KA, Repo-Tiihonen E, Naukkarinen H, Vanninen E, Tiihonen J, Uusitupa M. 2003. Psychopharmacology. 170: 89-93 -
Effects of ageing on serotonin transporters in healthy females
Kuikka JT, Tammela L, Bergström KA, Karhunen L, Uusitupa M, Tiihonen J. 2001. European journal of nuclear medicine and molecular imaging. 28: 911-913 -
Reduced serotonin transporter binding in binge eating women
Kuikka JT, Tammela L, Karhunen L, Rissanen A, Bergström KA, Naukkarinen H, Vanninen E, Karhu J, Lappalainen R, Repo-Tiihonen E, Tiihonen J, Uusitupa M. 2001. Psychopharmacology. 155: 310-314 -
Effect of orlistat treatment on body composition and resting energy expenditure during a two-year weight -reduction programme in obese Finns
Karhunen L, Franssila-Kallunki A, Rissanen P, Valve R, Kolehmainen M, Rissanen A, Uusitupa M. 2000. International journal of obesity. 24: 1567-1572 -
Regional cerebral blood flow during exposure to food in obese binge eating women
Karhunen LJ, Vanninen EJ, Kuikka JT, Lappalainen RI, Tiihonen J, Uusitupa MIJ. 2000. Psychiatry research: neuroimaging. 99: 29-42 -
Serum leptin and regional cerebral blood flow during exposure to food in obese and normal-weight women
Karhunen LJ, Lappalainen RI, Vanninen EJ, Kuikka JT, Uusitupa MIJ. 1999. Neuroendocrinology. 69: 154-159 -
The effect of orlistat on the fatty acid composition of serum lipid fractions in obese subjects
Vidgren HM, Ågren JJ, Valve RS, Karhunen LJ, Rissanen AM, Uusitupa MIJ. 1999. Clinical pharmacology and therapeutics. 66: 315-322 -
Regulation of Eating Behaviour in Human Obesity with Special Reference to Cephalic Phase Reactivity
Karhunen L. 1998. Kuopio University Publications D. Medical Sciences -
Serum leptin, food intake and preferences for sugar and fat in obese women
Karhunen LJ, Lappalainen RI, Haffner SM, Valve RH, Tuorila H, Miettinen H, Uusitupa MIJ. 1998. International journal of obesity. 1998: 819-821 -
Determinants of resting energy expenditure in obese non-diabetic caucasian women
Karhunen L, Franssila-Kallunki A, Rissanen A, Kervinen K, Kesäniemi YA, Uusitupa M. 1997. International journal of obesity. 21: 197-202 -
Regional cerebral blood flow during food exposure in obese and normal-weight womem
Karhunen LJ, Lappalainen RI, Vanninen EJ, Kuikka JT, Uusitupa MIJ. 1997. Brain. 120: 1675-1684 -
Serum leptin and short-term regulation of eating in obese women
Karhunen L, Haffner S, Lappalainen R, Turpeinen A, Miettinen H, Uusitupa M. 1997. Clinical science. 92: 573-578 -
Serum leptin in obesity is related to gender and body fat topography but does not predict successful weight loss
Niskanen LK, Haffner S, Karhunen LJ, Turpeinen AK, Miettinen H, Uusitupa MIJ. 1997. European journal of endocrinology. 137: 61-67 -
Serum leptin in relation to resting energy expenditure and fuel metabolism in obese subjects
Niskanen L, Haffner S, Karhunen LJ, Turpeinen AK, Miettinen H, Uusitupa MIJ. 1997. International journal of obesity. 21: 309-313 -
Subjective and physiological cephalic phase responses to food in obese binge-eating women
Karhunen LJ, Lappalainen RI, Tammela L, Turpeinen AK, Uusitupa MIJ. 1997. International journal of eating disorders. 21: 321-328 -
Apolipoprotein E phenotype modifies metabolic and hemodynamic abnormalities related to central obesity in women 1-3
Uusitupa MIJ, Karhunen L, Rissanen A, Franssila-Kallunki A, Niskanen L, Kervinen K, Kesäniemi YA. 1996. American journal of clinical nutrition. 64: 131-136 -
Determinants of the cephalic-phase insulin response in obese nondiabetic subjects
Karhunen LJ, Lappalainen RI, Niskanen LK, Turpeinen AK, Uusitupa MIJ. 1996. Metabolism: clinical and experimental. 45: 168-173 -
High cheese intake and faecal bacterial enzyme activities in the elderly
Salminen SJ, Mykkänen HM, Karhunen LJ, Ling W-H. 1995. International dairy journal. 5: 259-264 -
Effect of cheese on intestinal transit time and other indicators of bowel function in residents of a retirement home
Mykkänen HM, Karhunen LJ, Korpela R, Salminen S. 1994. Scandinavian journal of gastroenterology. 29: 29-32 -
Inhibition of anticipatory salivation and craving in response to food stimuli
Lappalainen R, Sjödén P-O, Karhunen L, Gladh V, Lesinska D. 1994. Physiology and behavior. 56: 393-398