Maija Lahtela-Kakkonen

We are studying epigenetic regulators involved in histone acetylation. We use drug design methods for identifying novel inhibitors and activators, and study their impact with in vitro assays and in various cell lines. We are focused on class III histodecatylases (HDACs) and Bromodomains (BRDs). In addition we are identifying novel compounds for various other targets such as prolyloligopeptidase (POP, PREP) and TRPA1, latter is linked in neuropathic pain. We are also modeling transporters and microplastics.