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Marjo Tuppurainen

Marjo Tuppurainen

Professor

Institute of Clinical Medicine, School of Medicine, Faculty of Health Sciences

marjo.tuppurainen@uef.fi

Information Publications

Research groups

Kuopio Musculoskeletal Research Unit (KMRU) 01.05.2003 -

Projects

Kuopio Osteoporosis Risk Factor and Prevention (OSTPRE) Study Finished 01.01.1989 - 31.12.2030

Publications

120/120 items

Gynekologinen syöpä verisen vuodon taustalla
Niskanen, Laura; Tuppurainen, Marjo. 2024. Duodecim. 140: 199-205
Iäkkään gynekologiset ongelmat tulee ottaa puheeksi
Niskanen, Laura; Tuppurainen, Marjo. 2023. Lääkärilehti. 78: 1433-1436
Metabolite Profiling of Osteoporosis and Atherosclerosis in Postmenopausal Women: A Cross-Sectional Study
Värri, Miika; Niskanen, Leo; Tuomainen, Tomi-Pekka; Honkanen, Risto; Kröger, Heikki; Tuppurainen, Marjo T. 2020. Vascular health and risk management. 16: 515-524
Ehkäisytablettien hyödyt ja haitat
Tuppurainen, Marjo. Teoksessa: Ruskoaho, Heikki; Hakkola, Jukka; Huupponen, Risto; Kantele, Anu; Korpi, Esa R; Moilanen, Eeva; Piepponen, Petteri; Savontaus, Eriika; Tenhunen, Olli; Vähäkangas, Kirsi(toim.) , 2019. Lääketieteellinen farmakologia ja toksikologia. s. 856-857. Kustannus Oy Duodecim
Ehkäisytablettien ja muun lääkehoidon yhteisvaikutukset
Tuppurainen, Marjo. Teoksessa: Ruskoaho, Heikki; Hakkola, Jukka; Huupponen, Risto; Kantele, Anu; Korpi, Esa R; Moilanen, Eeva; Piepponen, Petteri; Savontaus, Eriika; Tenhunen, Olli; Vähäkangas, Kirsi(toim.) , 2019. Lääketieteellinen farmakologia ja toksikologia. s. 857-858. Kustannus Oy Duodecim
Estrogeenien kliininen käyttö
Tuppurainen, Marjo. Teoksessa: Ruskoaho, Heikki; Hakkola, Jukka; Huupponen, Risto; Kantele, Anu; Korpi, Esa R; Moilanen, Eeva; Piepponen, Petteri; Savontaus, Eriika; Tenhunen, Olli; Vähäkangas, Kirsi(toim.) , 2019. Lääketieteellinen farmakologia ja toksikologia. s. 846-847. Kustannus Oy Duodecim
Estrogeenien synteesi ja vaikutukset
Tuppurainen, Marjo. Teoksessa: Ruskoaho, Heikki; Hakkola, Jukka; Huupponen, Risto; Kantele, Anu; Korpi, Esa R; Moilanen, Eeva; Piepponen, Petteri; Savontaus, Eriika; Tenhunen, Olli; Vähäkangas, Kirsi(toim.) , 2019. Lääketieteellinen farmakologia ja toksikologia. s. 843-846. Kustannus Oy Duodecim
Higher protein intake is associated with a lower likelihood of frailty among older women, Kuopio OSTPRE-Fracture Prevention Study
Isanejad, M; Sirola, J; Rikkonen, T; Mursu, J; Kröger, H; Qazi, SL; Tuppurainen, M; Erkkilä, AT. 2019. European journal of nutrition. 2020; 59: 1181-1189
Hormonaalinen ehkäisy ja hormonihoito
Tuppurainen, Marjo. Teoksessa: Tapanainen, Juha; Heikinheimo, Oskari; Mäkikallio, Kaarin(toim.) , 2019. Naistentaudit ja synnytykset. s. -. Kustannus Oy Duodecim
Hormonaalinen jälkiehkäisy
Tuppurainen, Marjo. Teoksessa: Ruskoaho, Heikki; Hakkola, Jukka; Huupponen, Risto; Kantele, Anu; Korpi, Esa R; Moilanen, Eeva; Piepponen, Petteri; Savontaus, Eriika; Tenhunen, Olli; Vähäkangas, Kirsi(toim.) , 2019. Lääketieteellinen farmakologia ja toksikologia. s. 860. Kustannus Oy Duodecim
Hormonikierukka
Tuppurainen, Marjo. Teoksessa: Ruskoaho, Heikki; Hakkola, Jukka; Huupponen, Risto; Kantele, Anu; Korpi, Esa R; Moilanen, Eeva; Piepponen, Petteri; Savontaus, Eriika; Tenhunen, Olli; Vähäkangas, Kirsi(toim.) , 2019. Lääketieteellinen farmakologia ja toksikologia. s. 859-860. Kustannus Oy Duodecim
Hormonit raskauden ehkäisyssä
Tuppurainen, Marjo. Teoksessa: Ruskoaho, Heikki; Hakkola, Jukka; Huupponen, Risto; Kantele, Anu; Korpi, Esa R; Moilanen, Eeva; Piepponen, Petteri; Savontaus, Eriika; Tenhunen, Olli; Vähäkangas, Kirsi(toim.) , 2019. Lääketieteellinen farmakologia ja toksikologia. s. 855. Kustannus Oy Duodecim
Ihonalaiset progestiinit
Tuppurainen, Marjo. Teoksessa: Ruskoaho, Heikki; Hakkola, Jukka; Huupponen, Risto; Kantele, Anu; Korpi, Esa R; Moilanen, Eeva; Piepponen, Petteri; Savontaus, Eriika; Tenhunen, Olli; Vähäkangas, Kirsi(toim.) , 2019. Lääketieteellinen farmakologia ja toksikologia. s. 858-859. Kustannus Oy Duodecim
Laskurit murtumariskin arviointiin
Tuppurainen, Marjo. Teoksessa: Tapanainen, Juha; Heikinheimo, Oskari; Mäkikallio, Kaarin(toim.) , 2019. Naistentaudit ja synnytykset. s. -. Kustannus Oy Duodecim
Luukadon lääkkeetön ehkäisy
Tuppurainen, Marjo. Teoksessa: Tapanainen, Juha; Heikinheimo, Oskari; Mäkikallio, Kaarin(toim.) , 2019. Naistentaudit ja synnytykset. s. -. Kustannus Oy Duodecim
Lääkkeenä käytettävien estrogeenien farmakokinetiikka
Tuppurainen, Marjo. Teoksessa: Ruskoaho, Heikki; Hakkola, Jukka; Huupponen, Risto; Kantele, Anu; Korpi, Esa R; Moilanen, Eeva; Piepponen, Petteri; Savontaus, Eriika; Tenhunen, Olli; Vähäkangas, Kirsi(toim.) , 2019. Lääketieteellinen farmakologia ja toksikologia. s. 846. Kustannus Oy Duodecim
Osteoporoosin diagnostiikka
Tuppurainen, Marjo. Teoksessa: Tapanainen, Juha; Heikinheimo, Oskari; Mäkikallio, Kaarin(toim.) , 2019. Naistentaudit ja synnytykset. s. -. Kustannus Oy Duodecim
Osteoporoosin lääkehoito
Tuppurainen, Marjo. Teoksessa: Tapanainen, Juha; Heikinheimo, Oskari; Mäkikallio, Kaarin(toim.) , 2019. Naistentaudit ja synnytykset. s. -. Kustannus Oy Duodecim
Osteoporoosin määritelmä ja yleisyys
Tuppurainen, Marjo. Teoksessa: Tapanainen, Juha; Heikinheimo, Oskari; Mäkikallio, Kaarin(toim.) , 2019. Naistentaudit ja synnytykset. s. -. Kustannus Oy Duodecim
Osteoporoosin riskiryhmät
Tuppurainen, Marjo. Teoksessa: Tapanainen, Juha; Heikinheimo, Oskari; Mäkikallio, Kaarin(toim.) , 2019. Naistentaudit ja synnytykset. s. -. Kustannus Oy Duodecim
Osteoporoosin syntymekanismi
Tuppurainen, Marjo. Teoksessa: Tapanainen, Juha; Heikinheimo, Oskari; Mäkikallio, Kaarin(toim.) , 2019. Naistentaudit ja synnytykset. s. -. Kustannus Oy Duodecim
Paikalliset ehkäisyvalmisteet
Tuppurainen, Marjo. Teoksessa: Ruskoaho, Heikki; Hakkola, Jukka; Huupponen, Risto; Kantele, Anu; Korpi, Esa R; Moilanen, Eeva; Piepponen, Petteri; Savontaus, Eriika; Tenhunen, Olli; Vähäkangas, Kirsi(toim.) , 2019. Lääketieteellinen farmakologia ja toksikologia. s. 861. Kustannus Oy Duodecim
Progesteronijohdokset
Tuppurainen, Marjo. Teoksessa: Ruskoaho, Heikki; Hakkola, Jukka; Huupponen, Risto; Kantele, Anu; Korpi, Esa R; Moilanen, Eeva; Piepponen, Petteri; Savontaus, Eriika; Tenhunen, Olli; Vähäkangas, Kirsi(toim.) , 2019. Lääketieteellinen farmakologia ja toksikologia. s. 850-852. Kustannus Oy Duodecim
Progesteronin kliininen käyttö
Tuppurainen, Marjo. Teoksessa: Ruskoaho, Heikki; Hakkola, Jukka; Huupponen, Risto; Kantele, Anu; Korpi, Esa R; Moilanen, Eeva; Piepponen, Petteri; Savontaus, Eriika; Tenhunen, Olli; Vähäkangas, Kirsi(toim.) , 2019. Lääketieteellinen farmakologia ja toksikologia. s. 849-850. Kustannus Oy Duodecim
Suun kautta otettavat ehkäisyvalmisteet
Tuppurainen, Marjo. Teoksessa: Ruskoaho, Heikki; Hakkola, Jukka; Huupponen, Risto; Kantele, Anu; Korpi, Esa R; Moilanen, Eeva; Piepponen, Petteri; Savontaus, Eriika; Tenhunen, Olli; Vähäkangas, Kirsi(toim.) , 2019. Lääketieteellinen farmakologia ja toksikologia. s. 855-856. Kustannus Oy Duodecim
Vaihdevuosioireiden hormonihoito
Tuppurainen, Marjo. Teoksessa: Ruskoaho, Heikki; Hakkola, Jukka; Huupponen, Risto; Kantele, Anu; Korpi, Esa R; Moilanen, Eeva; Piepponen, Petteri; Savontaus, Eriika; Tenhunen, Olli; Vähäkangas, Kirsi(toim.) , 2019. Lääketieteellinen farmakologia ja toksikologia. s. 847-848. Kustannus Oy Duodecim
Valikoivat estrogeenireseptorin muuntelijat ja selektiiviset progesteronireseptorin muuntelijat
Tuppurainen, Marjo. Teoksessa: Ruskoaho, Heikki; Hakkola, Jukka; Huupponen, Risto; Kantele, Anu; Korpi, Esa R; Moilanen, Eeva; Piepponen, Petteri; Savontaus, Eriika; Tenhunen, Olli; Vähäkangas, Kirsi(toim.) , 2019. Lääketieteellinen farmakologia ja toksikologia. s. 852-855. Kustannus Oy Duodecim
Effects of ethinyl estradiol-containing oral contraception and other factors on body composition and muscle strength among young healthy females in Finland-A cross-sectional study
Suuronen, Juha; Sjöblom, Samu; Tuppurainen, Marjo; Honkanen, Risto; Rikkonen, Toni; Kröger, Heikki; Sirola, Joonas. 2018. European journal of obstetrics and gynecology and reproductive biology. 2019; 232: 75-81
Postmenopausal hormone therapy and Alzheimer disease. A prospective cohort study
Imtiaz B, Tuppurainen M, Rikkonen T, Kivipelto M, Soininen H, Kröger H, Tolppanen A-M. 2017. Neurology. 88: 1062-1068
Association of adipokines and estradiol with bone and carotid calcifications in postmenopausal women
Värri M, Niskanen L, Tuomainen T, Honkanen R, Kröger H, Tuppurainen MT. 2016. Climacteric. 19: 204-211
Association of protein intake with bone mineral density and bone mineral content among elderly women: The OSTPRE Fracture Prevention Study
Isanejad M, Sirola J, Mursu J, Kröger H, Tuppurainen M, Erkkilä AT. 2016. Journal of nutrition health and aging. 2017; 21: 622-630
Association of protein intake with the change of lean mass among elderly women: The Osteoporosis Risk Factor and Prevention - Fracture Prevention Study (OSTPRE-FPS)
Isanejad Masoud, Mursu Jaakko, Sirola Joonas, Kröger Heikki, Rikkonen Toni, Tuppurainen Marjo, Erkkilä Arja T. 2015. Journal of nutritional science. 4: 1-8
Oophorectomy, Hysterectomy, and Risk of Alzheimer's Disease: A Nationwide Case-Control Study
Imtiaz Bushra, Tuppurainen Marjo, Tiihonen Miia, Kivipelto Miia, Soininen Hilkka, Hartikainen Sirpa, Tolppanen Anna-Maija. 2014. Journal of Alzheimer's disease. 42: 575-581
HT and SERMs in the long-term management of osteoporosis
Tuppurainen, M. 2012. Minerva ginecologica. 64: 195-205
Muscle strength and body composition are clinical indicators of osteoporosis
Rikkonen, T; Sirola, J; Salovaara, K; Tuppurainen, M; Jurvelin, JS; Honkanen, R; Kröger, H. 2012. Calcified tissue international. 91: 131-138
Should risk of bone fragility restrict weight control for other health reasons in postmenopausal women? - A ten year prospective study
Sirola Joonas, Rikkonen Toni, Tuppurainen Marjo, Honkanen Risto, Kröger Heikki. 2012. Maturitas. 71: 162-168
Sustained efficacy and safety of bazedoxifene in preventing fractures in postmenopausal women with osteoporosis: results of a 5-year, randomized, placebo-controlled study
Silverman, SL; Chines, AA; Kendler, DL; Kung, AW; Teglbjærg, CS; Felsenberg, D; Mairon, N; Constantine, GD; Adachi, JD; Bazedoxifene Study Group; Collaborators 249; Kröger, H; Tuppurainen, M. 2012. Osteoporosis international. 23: 351-63
The effect of hysterectomy or levonorgestrel-releasing intrauterine system on premenstrual symptoms in women treated for menorrhagia: secondary analysis of a randomized controlled trial
Leminen, H; Heliövaara-Peippo, S; Halmesmäki, K; Teperi, J; Grenman, S; Kivelä, A; Tuppurainen, M; Paavonen, J; Hurskainen, R. 2012. Acta obstetricia et gynecologica scandinavica. 91: 318-325
Validation of a semi-quantitative FFQ using food records as a reference in older women in the Kuopio Fracture Prefention Study (OSTPRE-FPS)
Erkkilä AT, Järvinen R, Karvonen H, Keronen L, Tuppurainen MT. 2012. Public health nutrition. 15: 635-639
Associations of dietary polyunsaturated fatty acids with bone mineral density in elderly women
Järvinen R, Tuppurainen M, Erkkilä AT, Penttinen P, Kärkkäinen M, Salovaara K, Jurvelin JS, Kröger H. 2011. European journal of clinical nutrition. 66: 496-503
Body fat distribution is associated with lumbar spine bone density independently of body weight in postmenopausal women
Saarelainen, Jarmo; Honkanen, Risto; Kröger, Heikki; Tuppurainen, Marjo; Jurvelin, Jukka; Niskanen, Leo. 2011. Maturitas. 69: 86-90
Body mass index and bone loss among postmenopausal women: the 10-year follow-up of the OSTPRE cohort
Saarelainen J, Kiviniemi V, Kröger H, Tuppurainen M, Niskanen L, Jurvelin J, Honkanen R. 2011. Journal of bone and mineral research. 30: 208-216
Bone health-related factors and the use of bisphosphonates in community setting - 15-year follow-up study
Sirola J, Salovaara K, Rikkonen T, Kärkkäinen M, Tuppurainen M, Jurvelin JS, Honkanen R, Kröger H. 2011. Osteoporosis international. 22: 255-264
Mikkeli Osteoporosis Index Identifies Fracture Risk Factors and Osteoporosis and Intervention Thresholds Parallel with FRAX
Ville Juhana Waris, Joonas P. Sirola, Vesa V. Kiviniemi, Marjo T. Tuppurainen, V. Pekka Waris. 2011. Journal of osteoporosis. 2011: 1-7
Osteoporoosi
Tuppurainen M, Komulainen M. Teoksessa: Olavi Ylikorkala, Juha Tapanainen(toim.) , 2011. Naistentaudit ja synnytykset, 5, uudistettu painos. s. 123-133. Kustannus Oy Duodecim
The effect of hysterectomy or levonorgestrel-releasing intrauterine system on cardiovascular disease risk factors in menorrhagia patients: A 10-year follow-up of a randomised trial
Heliövaara-Peippo S, Oksjoki R, Halmesmäki K, Kaaja R, Teperi J, Grenman S, Kivelä A, Surcel HM, Tomas E, Tuppurainen M, Hurskainen R, Paavonen J.. 2011. Maturitas. 69: 354-358
Validation of a semi-quantitative FFQ using food records as a reference in older women in the Kuopio Fracture Prevention Study (OSTPRE-FPS).
Erkkilä AT, Järvinen R, Karvonen H, Keronen L, Tuppurainen MT. 2011. Public health nutrition. 2011 online: 1-5
Bone Loss Rate May Interact with Other Risk Factors for Fractures among Elderly Women: A 15-Year Population-Based Study
Sirola J, Koistinen AK, Salovaara K, Rikkonen T, Tuppurainen M, Jurvelin JS, Honkanen R, Alhava E, Kröger H. 2010. Journal of osteoporosis. : 1-10
Correlates and predictors of self-rated health and ambulatory status among elderly women - Cross-sectional and 10 years population-based cohort study
Sirola J, Tuppurainen M, Rikkonen T, Honkanen R, Koivumaa-Honkanen H, Kröger H. 2010. Maturitas. 65: 244-252
Does daily vitamin D 800 IU and calcium 1000 mg supplementation decrease the risk of falling in ambulatory women aged 65-71 years? A 3-year randomized population-based trial (OSTPRE-FPS)
Kärkkäinen MK, Tuppurainen M, Salovaara K, Sandini L, Rikkonen T, Sirola J, Honkanen R, Arokoski J, Alhava E & Kröger H. 2010. Maturitas. 65: 359-365
Effect of calcium and vitamin D supplementation on bone mineral density in women aged 65-71 years: a 3-year randomized population-based trial (OSTPRE-FPS)
M. Kärkkäinen, M. Tuppurainen, K. Salovaara, L. Sandini, T. Rikkonen, J. Sirola, R. Honkanen, J. Jurvelin, E. Alhava & H. Kröger. 2010. Osteoporosis international. 21: 2047-2055
Effect of vitamin D(3) and calcium on fracture risk in 65- to 71-year-old women: a population-based 3-year randomized, controlled trial--the OSTPRE-FPS
Salovaara K, Tuppurainen M, Kärkkäinen M, Rikkonen T, Sandini L, Sirola J, Honkanen R, Alhava E, Kröger H. 2010. Journal of bone and mineral research. 25: 1487-1495
Effects of continuous combined hormone replacement therapy and clodronate on bone mineral density in osteoporotic postmenopausal women: A 5-year follow-up
Tuppurainen M, Härmä K, Komulainen M, Kiviniemi V, Kröger H, Honkanen R, Alhava E, Jurvelin J, Saarikoski S. 2010. Maturitas. 66: 423-430
Natural seroconversion to high-risk human papillomaviruses (hrHPVs) is not protective against related HPV genotypes
Johanna Palmrooth, Proscovia Namujju, Aline Simen-Kapeu, Vesa Kataja, Heljä-Marja Surcel, Marjo Tuppurainen, Merja Yliskoski, Kari Syrjänen & Matti Lehtinen. 2010. Scandinavian journal of infectious diseases. 42: 379-384
Physical activity slows femoral bone loss but promotes wrist fractures in postmenopausal women: a 15-year follow-up of the OSTPRE study
Rikkonen T, Salovaara K, Sirola J, Kärkkäinen M, Tuppurainen M, Jurvelin J, Honkanen R, Alhava E, Kröger H. 2010. Journal of bone and mineral research. vol 25: 2332-2340
The effect of hysterectomy or levonorgestrel-relaeasing intrauterine system on lower urinary tract symptoms: a 10-year follof-up study of a randomised trial
Heliövaara-Peippo S, Halmesmäki K, Hurskainen R, Grenman S, Kivelä A, Tomas E, Tuppurainen M & Paavonen J. 2010. Bjog: an international journal of obstetrics and gynaecology. 117: 602-609
Hormone therapy protects from diabetes: the Kuopio osteoporosis risk factor and prevention study
Pentti K, Tuppurainen MT, Honkanen R, Sandini L, Kröger H, Alhava E, Saarikoski S. 2009. European journal of endocrinology. 160: 979-983
Nilkkamurtumien vaaratekijät - OSTPRE-murtumakohortin väestöpohjainen riskitekijäanalyysi 13,9 vuoden seurannassa
Salovaara K, Hietala J, Rikkonen T, Sirola J, Tuppurainen M, Kröger H. 2009. Suomen Ortopedia ja Traumatologia. 32: 310-313
Physical tests for patient selection for bone mineral density measurements in postmenopausal women
Kärkkäinen M, Rikkonen T, Kröger H, Sirola J, Tuppurainen M, Salovaara K, Arokoski J, Jurvelin J, Honkanen R, Alhava E. 2009. Bone. 44: 660-665
Sister's fracture history may be associated with perimenopausal bone fragility and modifies the predictability of fracture risk
Sirola J, Salovaara K, Tuppurainen M, Jurvelin JS, Alhava E, Kröger H. 2009. Osteoporosis international. 20: 557-565
The effect of hysterectomy or levonorgestrel-releasing intrauterine system on lower abdominal pain and back pain among women treated for menorrhagia: a five-year randomized controlled trial
Heliövaara-Peippo S, Halmesmäki K, Hurskainen R, Teperi J, Grenman S, Kivelä A, Kujansuu E, Tuppurainen M, Vuorma S, Yliskoski M, Paavonen J. 2009. Acta obstetricia et gynecologica scandinavica. 88: 1389-1396
Use of calcium supplements and the risk of coronary heart disease in 52-62-year-old women: The Kuopio Osteoporosis Risk Factor and Prevention Study
Pentti K, Tuppurainen MT, Honkanen R, Sandini L, Kröger H, Alhava E, Saarikoski S. 2009. Maturitas. 63: 73-78
Agreement of self-reported estrogen use with prescription data: an analysis of women from the Kuopio osteoporosis risk factor and prevention study (OSTPRE)
Sandini L, Pentti K, Tuppurainen M, Kröger H, Honkanen R. 2008. Menopause: the journal of the north american menopause society. 15: 282-289
Association between functional capacity tests and fractures: an eight-year prospective population-based cohort study
Kärkkäinen M, Rikkonen T, Kröger H, Sirola J, Tuppurainen M, Salovaara K, Arokoski J, Jurvelin J, Honkanen R, Alhava E. 2008. Osteoporosis international. 19: 1203-1210
Efficacy of Bazedoxifene in Reducing New Vertebral Fracture Risk in Postmenopausal Women With Osteoporosis: Results From a 3-Year, Randomized, Placebo-, and Active-Controlled Clinical Trial
Silverman SL, Cristiansen C, Genant HK, Vukicevic S, Zanchetta JR, de VILLIERS Tj, Constantine GD, Chines AA, Kröger H, Tuppurainen M. 2008. Journal of bone and mineral research. 23: 1923-1934
Grip strength may facilitate fracture prediction in perimenopausal women with normal BMD: a 15-year population-based study
Sirola J, Rikkonen T, Tuppurainen M, Jurvelin JS, Alhava E, Kröger H. 2008. Calcified tissue international. 83: 93-100
Onko pitkäaikainen hormonaalinen ehkäisy turvallista?
Backman T, Metsä-Heikkilä M, Tuppurainen M. 2008. Duodecim. 124: 445-50
Is discordance in bone measurements affected by body composition or anthropometry? A comparative study between peripheral and central devices
Saarelainen J, Rikkonen T, Honkanen R, Kröger H, Tuppurainen M, Niskanen L, Jurvelin JS. 2007. Journal of clinical densitometry. 10: 312-318
Association of grip strength change with menopausal bone loss and related fractures: A population-based follow-up study
Sirola J, Rikkonen T, Tuppurainen M, Jurvelin JS, Kröger H, Kröger H. 2006. Calcified tissue international. 78: 218-226
Distance of walking in childhood and femoral bne density in perimenopausal women
Rikkonen T, Tuppurainen M, Kröger H, Jurvelin J, Honkanen R, Kröger H. 2006. European journal of applied physiology. 97: 509-515
Effects of ospemifene and raloxifene on biochemical markers of bone turnover in postmenopausal women
Komi J, Lankinen KS, DeGregorio M, Heikkinen J, Saarikoski S, Tuppurainen M, Halonen K, Lammintausta R, Väänänen K, Ylikorkala O, Erkkola R. 2006. Journal of bone and mineral metabolism. 24: 314-318
Fracture risk and bone density of peri- and early postmenopausal women with uterine leiomyomas
Randell KM, Honkanen RJ, Tuppurainen MT, Kröger H, Jurvelin JS, Saarikoski S, Kröger H. 2006. Maturitas. 53: 333-342
Hormone replacement therapy and mortality in 52- to 70-year-old women: the Kuopio Osteoporosis Risk Factor and Prevention Study
Pentti K, Honkanen R, Tuppurainen MT, Sandini L, Kröger H, Saarikoski S, Kröger H. 2006. European journal of endocrinology. 154: 101-107
Maintenance of muscle strength may counteract weight-loss-related postmenopausal bone loss - a population based approach
Sirola J, Rikkonen T, Tuppurainen M, Honkanen R, Jurvelin JS, Kröger H. 2006. Osteoporosis international. 17: 775-782
Mikkelin Osteoporoosi -indeksi (MOI) ennustaa osteoporoottisia murtumia
Sirola J, Waris V, Tuppurainen M, Kiviniemi V, Waris P. 2006. Suomen Ortopedia ja Traumatologia. 29: 310-312
Periytyvätkö osteoporoosi ja luunmurtumat?
Tuppurainen M, Kröger H, Mahonen A, Kröger H. 2006. Duodecim
Associations between grip strength change and axial postmenopausal bone loss-a 10-year population-based follow-up study
Sirola J, Tuppurainen M, Honkanen R, Jurvelin JS, Kröger H, Kröger H. 2005. Osteoporosis international. 16: 1841-1848
Cross-calibration of lunar DPX-IQ and DPX dual-energy X-ray densitometers for bone mineral measurements in women
Saarelainen J, Honkanen R, Vanninen E, Kröger H, Tuppurainen M, Niskanen L, Jurvelin JS. 2005. Journal of clinical densitometry. 8: 320-329
High bone mineral density among perimenopausal women
Pesonen J, Sirola J, Tuppurainen M, Jurvelin J, Alhava E, Honkanen R, Kröger H, Kröger H. 2005. Osteoporosis international. 16: 1899-1906
Factors related to postmenopausal muscle performance: a cross-sectional population-based study
Sirola J, Rikkonen T, Kröger H, Honkanen R, Tuppurainen M, Airaksinen O, Saarikoski S, Kröger H. 2004. European journal of applied physiology. 93: 102-107
Leucine7 to proline7 polymorphism in prepro-NPY gene and femoral neck bone mineral density in postmenopausal women
Heikkinen A-M, Niskanen LK, Salmi JA, Koulu M, Pesonen U, Uusitupa MIJ, Komulainen MH, Tuppurainen MT, Kröger H, Jurvelin J, Saarikoski S, Kröger H. 2004. Bone. 35: 589-594
Osteoporoosi
Tuppurainen M, Komulainen M. Teoksessa: Ylikorkala O, Kauppila A(toim.) , 2004. Naistentaudit ja synnytykset. 4. uud. p.. s. 127-134. Duodecim
The combined contraceptive vaginal ring (NuvaRing) and lipid metabolism: a comparative study
Tuppurainen M, Klimscheffskij R, Venhola M, Dieben OM. 2004. Contraception. 69: 389-394
Changes in body weight and onset of hypertension in perimenopausal women
Juntunen M, Niskanen L, Saarelainen J, Tuppurainen M, Saarikoski S, Honkanen R. 2003. Journal of human hypertension. 17: 775-779
Estrogens and aging
Tuppurainen M, Saarikoski S. Teoksessa: Gordin A, Kaakkola S, Teräväinen H(toim.) , 2003. Parkinson¿s Disease. The XIV International Congress on Parkinson's Disease. s. 101-106. Lippincott Williams & Wilkins
Factors affecting bone loss around menopause in women with HRT: a prospective study
Sirola J, Kröger H, Honkanen R, Jurvelin JS, Sandini L, Tuppurainen MT, Saarikoski S, Kröger H. 2003. Maturitas. 45: 159-167
Interaction of nutritional calcium and HRT in prevention of postmenopausal bone loss: a prospective study
Sirola J, Kröger H, Sandini L, Tuppurainen M, Jurvelin JS, Saarikoski S, Honkanen R, Kröger H. 2003. Calcified tissue international. 72: 659-65
Luut murtuvat ilman estrogeenia
Komulainen M, Tuppurainen M, Kröger H, Kröger H, Tuppurainen M. 2003. Duodecim. 119: 2183-2189
Risk factors associated with peri- and postmenopausal bone loss: does HRT prevent weight loss-related bone loss?
Sirola J, Kröger H, Honkanen R, Sandini L, Tuppurainen M, Jurvelin JS, Saarikoski S. 2003. Osteoporosis international. 14: 27-33
Smoking may impair the bone protective effects of nutritional calcium: a population-based approach
Sirola J, Kröger H, Honkanen R, Sandini L, Tuppurainen M, Jurvelin JS, Saarikoski S. 2003. Journal of bone and mineral research. 18: 1036-1042
When and how should bone mineral density be measured?
Tuppurainen M. 2003. Acta obstetricia et gynecologica scandinavica. 82: 395-397
Does postmenopausal hormone replacement therapy affect cardiac autonomic regulation in osteoporotic women?
Niskanen L, Laitinen T, Tuppurainen M, Saarikoski S, Kröger H, Alhava E, Hartikainen J. 2002. Menopause: the journal of the north american menopause society. 9: 52-57
Lifestyle and other factors predict ankle fractures in perimenopausal women: A population-based prospective cohort study
Valtola A, Honkanen R, Kröger H, Tuppurainen M, Saarikoski S, Alhava E. 2002. Bone. 30: 238-242
Effect of calcium on bone loss and fractures according to estrogen repletion status
Honkanen R, Komulainen M, Kröger H, Tuppurainen M, Alhava E, Saarikoski S. Teoksessa: Burckhardt P, Dawson-Hughes B, Heaney RP(toim.) , 2001. Nutritional Aspects of Osteoporosis. s. 51-64. Academic Press
Hormone replacement therapy and risk of falling in early postmenopausal women-a population-based stydy
Randell KM, Honkanen RJ, Komulainen MH, Tuppurainen MT, Kröger H, Saarikoski S. 2001. Clinical endocrinology. 54: 769-774
Leisure-time physical activity and rate of bone loss among peri- and postmenopausal women: a longitudinal study
Puntila E, Kröger H, Lakka T, Tuppurainen M, Jurvelin J, Honkanen R. 2001. Bone. 29: 442-446
Does apolipoprotein E genotype relate to BMD and bone markers in postmenopausal women?
Heikkinen AM, Kröger H, Niskanen L, Komulainen MH, Ryynänen M, Parviainen MT, Tuppurainen MT, Honkanen R, Saarikoski S. 2000. Maturitas. 34: 33-41
Identification of early postmenopausal women with no bone response to HRT: results of a 5-year clinical trial
Komulainen M, Kröger H, Tuppurainen MT, Heikkinen A-M, Honkanen R, Saarikoski S. 2000. Osteoporosis international. 11: 211-218
Is the response of serum lipids and lipoproteins to postmenopausal hormone replacement therapy modified by ApoE genotype?
Heikkinen A-M, Niskanen L, Ryynänen M, Komulainen MH, Tuppurainen MT, Parviainen M, Saarikoski S. 1999. Arteriosclerosis, thrombosis, and vascular biology. 19: 402-407
Prevention of femoral and lumbar bone loss with hormone replacement therapy and vitamin D3 in early postmenopausal women: a population-based 5-year randomized trial
Komulainen M, Kröger H, Tuppurainen MT, Heikkinen A-M, Alhava E, Honkanen R, Jurvelin J, Saarikoski S. 1999. Journal of clinical endocrinology and metabolism. 84: 546-552
Does vitamin D strengthen the increase in femoral neck BMD in osteoporotic women treated with estrogen?
Tuppurainen MT, Komulainen M, Kröger H, Honkanen R, Jurvelin J, Puntila E, Heikkinen AM, Alhava E, Saarikoski S. 1998. Osteoporosis international. 7: 32-38
Effects of postmenopausal hormone replacement therapy with and without vitamin D3 on circulating levels of 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D
Heikkinen A-M, Parviainen MT, Tuppurainen MT, Niskanen L, Komulainen MH, Saarikoski S. 1998. Calcified tissue international. 62: 26-30
HRT and vit D in prevention of non-vertebral fractures in postmenopausal women: a 5 year randomized trial
Komulainen MH, Kröger H, Tuppurainen MT, Heikkinen A-M, Alhava E, Honkanen R, Saarikoski S. 1998. Maturitas. 31: 45-54
Postmenopausal hormone replacement therapy and autoantibodies against oxidized LDL
Heikkinen A-M, Niskanen L, Ylä-Herttuala S, Luoma J, Tuppurainen MT, Komulainen M, Saarikoski S. 1998. Maturitas. 29: 155-161
Relationships between risk factors and fractures differ by type of fracture: a population-based study of 12192 perimenopausal women
Honkanen R, Tuppurainen M, Kröger H, Alhava E, Saarikoski S. 1998. Osteoporosis international. 8: 25-31
Associations of early premenopausal fractures with subsequent fractures vary by sites and mechanisms of fractures
Honkanen R, Tuppurainen M, Kroger H, Alhava E, Puntila E. 1997. Calcified tissue international. 60: 327-331
Biochemical bone markers and bone mineral density during postmenopausal hormone replacement therapy with and without vitamin D3: A prospective, controlled, randomized stydy
Heikkinen A-M, Parviainen M, Niskanen L, Komulainen M, Tuppurainen MT, Kröger H, Saarikoski S. 1997. Journal of clinical endocrinology and metabolism. 82: 2476-2482
Lactose intolerance associated with fractures of weight-bearing bones in finnish women aged 38-57 years
Honkanen R, Kröger H, Alhava E, Turpeinen P, Tuppurainen M, Saarikoski S. 1997. Bone. 21: 473-477
Long-term vitamin D3 supplementation may have adverse effects on serum lipids during postmenopausal hormone replacement therapy
Heikkinen A-M, Tuppurainen MT, Niskanen L, Komulainen M, Penttilä I, Saarikoski S. 1997. European journal of endocrinology. 137: 495-502
Physical activity in adolescence and bone density in peri- and postmenopausal women: A population-based study
Puntila E, Kröger H, Lakka T, Honkanen R, Tuppurainen M. 1997. Bone. 21: 363-367
Vitamin D and HRT: No benefit additional to that of HRT alone in prevention of bone loss in early postmenopausal women. A 2.5-year randomized placebo-controlled stydy
Komulainen M, Tuppurainen MT, Kröger H, Heikkinen AM, Puntila E, Alhava E, Honkanen R, Saarikoski S. 1997. Osteoporosis international. 7: 126-132
Does lactose intolerance predispose to low bone density? A population-based study of perimenopausal Finnish women
Honkanen R, Pulkkinen P, Järvinen R, Kröger H, Lindstedt K, Tuppurainen M, Uusitupa M. 1996. Bone. 19: 23-28
Does vitamin D3 have negative effects on serum levels of lipids? A follow-up study with a sequential combination of estradiol valerate and cyproterone acetate and/or vitamin D3
Tuppurainen M, Heikkinen A-M, Penttilä I, Saarikoski S. 1995. Maturitas. 22: 55-61
Fractures and low axial bone density in perimenopausal women
Honkanen R, Kröger H, Tuppurainen M, Alhava E, Saarikoski S. 1995. Journal of clinical epidemiology. 48: 881-888
Osteoporosis Risk Factors and Fractures Among Perimenopausal Women Women
Tuppurainen M. 1995. Kuopio University Publications D. Medical Sciences
Prediction of fracture risk using axial bone mineral density in a perimenopausal population: a prospective study
Kröger H, Huopio J, Honkanen R, Tuppurainen M, Puntila E, Alhava E, Saarikoski S. 1995. Journal of bone and mineral research. 10: 302-306
Risks of perimenopausal fractures - a prospective population-based study
Tuppurainen M, Kröger H, Honkanen R, Puntila E, Huopio J, Saarikoski S, Alhava E. 1995. Acta obstetricia et gynecologica scandinavica. 74: 624-628
The effect of gynecological risk factors on lumbar and femoral bone mineral density in peri- and postmenopausal women
Tuppurainen M, Kröger H, Saarikoski S, Honkanen R, Alhava E. 1995. Maturitas. 21: 137-145
The effect of fluoridated drinking water on axial bone mineral density - a population-based study
Kröger H, Alhava E, Honkanen R, Tuppurainen M, Saarikoski S. 1994. BONE AND MINERAL. 27: 33-41
The effect of previous oral contraceptive use on bone mineral density in perimenopausal women
Tuppurainen M, Kröger H, Saarikoski S, Honkanen R, Alhava E. 1994. Osteoporosis international. 4: 93-98

University of Eastern Finland Joensuu, Kuopio © University of Eastern Finland

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Marjo Tuppurainen

Research groups

Projects

Gynekologinen syöpä verisen vuodon taustalla

Iäkkään gynekologiset ongelmat tulee ottaa puheeksi

Metabolite Profiling of Osteoporosis and Atherosclerosis in Postmenopausal Women: A Cross-Sectional Study

Ehkäisytablettien hyödyt ja haitat

Ehkäisytablettien ja muun lääkehoidon yhteisvaikutukset

Estrogeenien kliininen käyttö

Estrogeenien synteesi ja vaikutukset

Higher protein intake is associated with a lower likelihood of frailty among older women, Kuopio OSTPRE-Fracture Prevention Study

Hormonaalinen ehkäisy ja hormonihoito

Hormonaalinen jälkiehkäisy

Hormonikierukka

Hormonit raskauden ehkäisyssä

Ihonalaiset progestiinit

Laskurit murtumariskin arviointiin

Luukadon lääkkeetön ehkäisy

Lääkkeenä käytettävien estrogeenien farmakokinetiikka

Osteoporoosin diagnostiikka

Osteoporoosin lääkehoito

Osteoporoosin määritelmä ja yleisyys

Osteoporoosin riskiryhmät

Osteoporoosin syntymekanismi

Paikalliset ehkäisyvalmisteet

Progesteronijohdokset

Progesteronin kliininen käyttö

Suun kautta otettavat ehkäisyvalmisteet

Vaihdevuosioireiden hormonihoito

Valikoivat estrogeenireseptorin muuntelijat ja selektiiviset progesteronireseptorin muuntelijat

Effects of ethinyl estradiol-containing oral contraception and other factors on body composition and muscle strength among young healthy females in Finland-A cross-sectional study

Postmenopausal hormone therapy and Alzheimer disease. A prospective cohort study

Association of adipokines and estradiol with bone and carotid calcifications in postmenopausal women

Association of protein intake with bone mineral density and bone mineral content among elderly women: The OSTPRE Fracture Prevention Study

Association of protein intake with the change of lean mass among elderly women: The Osteoporosis Risk Factor and Prevention - Fracture Prevention Study (OSTPRE-FPS)

Oophorectomy, Hysterectomy, and Risk of Alzheimer's Disease: A Nationwide Case-Control Study

HT and SERMs in the long-term management of osteoporosis

Muscle strength and body composition are clinical indicators of osteoporosis

Should risk of bone fragility restrict weight control for other health reasons in postmenopausal women? - A ten year prospective study

Sustained efficacy and safety of bazedoxifene in preventing fractures in postmenopausal women with osteoporosis: results of a 5-year, randomized, placebo-controlled study

The effect of hysterectomy or levonorgestrel-releasing intrauterine system on premenstrual symptoms in women treated for menorrhagia: secondary analysis of a randomized controlled trial

Validation of a semi-quantitative FFQ using food records as a reference in older women in the Kuopio Fracture Prefention Study (OSTPRE-FPS)

Associations of dietary polyunsaturated fatty acids with bone mineral density in elderly women

Body fat distribution is associated with lumbar spine bone density independently of body weight in postmenopausal women

Body mass index and bone loss among postmenopausal women: the 10-year follow-up of the OSTPRE cohort

Bone health-related factors and the use of bisphosphonates in community setting - 15-year follow-up study

Mikkeli Osteoporosis Index Identifies Fracture Risk Factors and Osteoporosis and Intervention Thresholds Parallel with FRAX

Osteoporoosi

The effect of hysterectomy or levonorgestrel-releasing intrauterine system on cardiovascular disease risk factors in menorrhagia patients: A 10-year follow-up of a randomised trial

Validation of a semi-quantitative FFQ using food records as a reference in older women in the Kuopio Fracture Prevention Study (OSTPRE-FPS).

Bone Loss Rate May Interact with Other Risk Factors for Fractures among Elderly Women: A 15-Year Population-Based Study

Correlates and predictors of self-rated health and ambulatory status among elderly women - Cross-sectional and 10 years population-based cohort study

Does daily vitamin D 800 IU and calcium 1000 mg supplementation decrease the risk of falling in ambulatory women aged 65-71 years? A 3-year randomized population-based trial (OSTPRE-FPS)

Effect of calcium and vitamin D supplementation on bone mineral density in women aged 65-71 years: a 3-year randomized population-based trial (OSTPRE-FPS)

Effect of vitamin D(3) and calcium on fracture risk in 65- to 71-year-old women: a population-based 3-year randomized, controlled trial--the OSTPRE-FPS

Effects of continuous combined hormone replacement therapy and clodronate on bone mineral density in osteoporotic postmenopausal women: A 5-year follow-up

Natural seroconversion to high-risk human papillomaviruses (hrHPVs) is not protective against related HPV genotypes

Physical activity slows femoral bone loss but promotes wrist fractures in postmenopausal women: a 15-year follow-up of the OSTPRE study

The effect of hysterectomy or levonorgestrel-relaeasing intrauterine system on lower urinary tract symptoms: a 10-year follof-up study of a randomised trial

Hormone therapy protects from diabetes: the Kuopio osteoporosis risk factor and prevention study

Nilkkamurtumien vaaratekijät - OSTPRE-murtumakohortin väestöpohjainen riskitekijäanalyysi 13,9 vuoden seurannassa

Physical tests for patient selection for bone mineral density measurements in postmenopausal women

Sister's fracture history may be associated with perimenopausal bone fragility and modifies the predictability of fracture risk

The effect of hysterectomy or levonorgestrel-releasing intrauterine system on lower abdominal pain and back pain among women treated for menorrhagia: a five-year randomized controlled trial

Use of calcium supplements and the risk of coronary heart disease in 52-62-year-old women: The Kuopio Osteoporosis Risk Factor and Prevention Study

Agreement of self-reported estrogen use with prescription data: an analysis of women from the Kuopio osteoporosis risk factor and prevention study (OSTPRE)

Association between functional capacity tests and fractures: an eight-year prospective population-based cohort study

Efficacy of Bazedoxifene in Reducing New Vertebral Fracture Risk in Postmenopausal Women With Osteoporosis: Results From a 3-Year, Randomized, Placebo-, and Active-Controlled Clinical Trial

Grip strength may facilitate fracture prediction in perimenopausal women with normal BMD: a 15-year population-based study

Onko pitkäaikainen hormonaalinen ehkäisy turvallista?

Is discordance in bone measurements affected by body composition or anthropometry? A comparative study between peripheral and central devices

Association of grip strength change with menopausal bone loss and related fractures: A population-based follow-up study

Distance of walking in childhood and femoral bne density in perimenopausal women

Effects of ospemifene and raloxifene on biochemical markers of bone turnover in postmenopausal women

Fracture risk and bone density of peri- and early postmenopausal women with uterine leiomyomas

Hormone replacement therapy and mortality in 52- to 70-year-old women: the Kuopio Osteoporosis Risk Factor and Prevention Study

Maintenance of muscle strength may counteract weight-loss-related postmenopausal bone loss - a population based approach

Mikkelin Osteoporoosi -indeksi (MOI) ennustaa osteoporoottisia murtumia

Periytyvätkö osteoporoosi ja luunmurtumat?