MARKUS STORVIK

Contact info

Research groups - UEF

• 
  Neuropharmacology and Drug Targets Consortium (NDTC)

Publications

• Bjelogrlic-Laakso, Nina; Vuoti, Heidi; Storvik, Markus. 2020. Lääkehoito osastohoidossa olevilla kehitysvammaisilla eri autismikirjon potilailla Dosis 36 1: 24-34. 2020
• Laukkanen, V; Kärkkäinen, O; Kautiainen, H; Tiihonen, J; Storvik, M. 2019. Increased [³H]quisqualic acid binding density in the dorsal striatum and anterior insula of alcoholics: A post-mortem whole-hemisphere autoradiography study Psychiatry research: neuroimaging 287: 63-69. 2019
• Tiihonen, J; Koskuvi, M; Storvik, M; Hyötyläinen, I; Gao, Y; Puttonen, KA; Giniatullina, R; Poguzhelskaya, E; Ojansuu, I; Vaurio, O; Cannon, TD; Lönnqvist, J; Therman, S; Suvisaari, J; Kaprio, J; Cheng, L; Hill, AF; Lähteenvuo, M; Tohka, J; Giniatullin, R; et al.. 2019. Sex-specific transcriptional and proteomic signatures in schizophrenia Nature communications 10 1: 3933. 2019
• Biomarkers of Toxicity in Human Placenta [Chapter 18]. Vähäkangas, Kirsi; Loikkanen, Jarkko; Sahlman, Heidi; Karttunen, Vesa; Repo, Jenni; Sieppi, Elina; Kummu, Maria; Huuskonen, Pasi; Myöhänen, Kirsi; Storvik, Markus; Pasanen, Markku; Myllynen, Päivi; Pelkonen, Olavi / Biomarkers in Toxicology (Second edition). 2019. 2019
• Pesonen M, Rysä J, Storvik M, Rilla K, Pasanen M, Vähäkangas K. 2017. Molecular targets of chloropicrin in human airway epithelial cells. TOXICOLOGY IN VITRO 42: 247-254. 2017
• Tiihonen Jari, Halonen Pirjo, Tiihonen Laura, Kautiainen Hannu, Storvik Markus, Callaway James. 2017. The Association of Ambient Temperature and Violent Crime. Scientific Reports 7: 6543. 2017
• Niku Mikael, Pajari Anne-Maria, Sarantaus Laura, Päivärinta Essi, Storvik Markus, Heiman-Lindh Anu, Suokas Santeri, Nyström Minna, Mutanen Marja. 2016. Western diet enhances intestinal tumorigenesis in Min/+ mice, associating with mucosal metabolic and inflammatory stress and loss of Apc heterozygosity. JOURNAL OF NUTRITIONAL BIOCHEMISTRY 2017; 39: 126-133. 2016
• Päivärinta Essi, Niku Mikael, Maukonen Johanna, Storvik Markus, Heiman-Lindh Anu, Saarela Maria, Pajari Anne-Maria, Mutanen Marja. 2016. Changes in intestinal immunity, gut microbiota, and expression of energy metabolism-related genes explain adenoma growth in bilberry and cloudberry-fed ApcMin mice. NUTRITION RESEARCH 36 11: 1285-1297. 2016
• Kärkkäinen Olli, Häkkinen Merja R, Auriola Seppo, Kautiainen Hannu, Tiihonen Jari, Storvik Markus. 2016. Increased steroid hormone dehydroepiandrosterone and pregnenolone levels in post-mortem brain samples of alcoholics. ALCOHOL 52: 63-70. 2016
• Huuskonen Pasi, Amezaga Maria R, Bellingham Michelle, Jones Lucy H, Storvik Markus, Häkkinen Merja, Keski-Nisula Leea, Heinonen Seppo, O'Shaughnessy Peter J, Fowler Paul A, Pasanen Markku. 2016. The human placental proteome is affected by maternal smoking. REPRODUCTIVE TOXICOLOGY 63: 22-31. 2016
• Laitinen Kirsti, Storvik Markus, Ulrich Tacke. 2015. Voiko aivojen toimintaa tehostaa kognition kohentajalla?. Sic! Lääketietoa Fimeasta 1/2015: -. 2015
• Laukkanen Virpi, Kärkkäinen Olli, Kautiainen Hannu, Tiihonen Jari, Storvik Markus. 2015. Decreased [³H]naloxone Binding in the Dentate Gyrus of Cloninger Type 1 Anxiety-Prone Alcoholics: A Postmortem Whole-Hemisphere Autoradiography Study. ALCOHOLISM, CLINICAL AND EXPERIMENTAL RESEARCH 39 8: 1352-1359. 2015
• Pesonen Maija, Storvik Markus, Kokkola Tarja, Rysä Jaana, Vähäkangas Kirsi, Pasanen Markku. 2015. Transcriptomic Analysis of Human Primary Bronchial Epithelial Cells after Chloropicrin Treatment. CHEMICAL RESEARCH IN TOXICOLOGY 28 10: 1926-1935. 2015
• Nieminen P, Mustonen A-M, Myllykangas M, Raunio H, Storvik M. 2014. Mitä terveystieteiden opiskelijoiden tulisi tietää uskomushoidoista?. Yliopistopedagogiikka 21 2: 39-43. 2014
• Vähäkangas Kirsi, Loikkanen Jarkko, Sahlman Heidi, Karttunen Vesa, Repo Jenni, Sieppi Elina, Kummu Maria, Huuskonen Pasi, Myöhänen Kirsi, Storvik Markus, Pasanen Markku, Myllynen Päivi, Pelkonen Olavi. 2014. Biomarkers of toxicity in human placenta [Chapter 20]: Gupta Ramesh C, Biomarkers in Toxicology. 325-360. 2014
• Storvik Markus, Laukkanen Virpi, Kupila Jukka, Kärkkäinen Olli. 2014. Alkoholismin autoradiografiatutkimus. DOSIS : FARMASEUTTINEN AIKAKAUSKIRJA 30 3: 217. 2014
• Storvik Markus, Huuskonen Pasi, Pehkonen Petri, Pasanen Markku. 2014. The unique characteristics of the placental transcriptome and the hormonal metabolism enzymes in placenta. REPRODUCTIVE TOXICOLOGY 47: 9-14. 2014
• Pelkonen Olavi, Pasanen Markku, Tolonen Ari, Koskinen Mikko, Hakkola Jukka, Abass Khaled, Laine Jaana, Häkkinen Merja, Juvonen Risto, Auriola Seppo, Storvik Markus, Huuskonen Pasi, Rousu Timo, Rahikkala Maiju. 2014. Reactive Metabolites in Early Drug Development: Predictive in Vitro Tools. CURRENT MEDICINAL CHEMISTRY (SCHIPHOL) 2015; 22: 538-550. 2014
• Kärkkäinen Olli, Laukkanen Virpi, Haukijärvi Tuija, Kautiainen Hannu, Tiihonen Jari, Storvik Markus. 2014. Lower [3H]Citalopram Binding in Brain Areas Related to Social Cognition in Alcoholics. ALCOHOL AND ALCOHOLISM 2015; 50 1: 46-50. 2014
• Marttinen Maija, Pajari Anne-Maria, Päivärinta Essi, Storvik Markus, Marttinen Pekka, Nurmi Tanja, Niku Mikael, Piironen Vieno, Mutanen Marja. 2014. Plant sterol feeding induces tumor formation and alters sterol metabolism in the intestine of Apc(Min) mice. NUTRITION AND CANCER 66: 259-269. 2014
• Lempiäinen Juha, Finckenberg Piet, Mervaala Elina E, Storvik Markus, Kaivola Juha, Lindstedt Ken, Levijoki Jouko, Mervaala Eero M. 2014. Dexmedetomidine preconditioning ameliorates kidney ischemia-reperfusion injury. Pharmacology Research & Perspectives 2 3: e00045. 2014
• Laukkanen Virpi, Kärkkäinen Olli, Kupila Jukka, Kautiainen Hannu, Tiihonen Jari, Storvik Markus. 2014. Increased metabotropic glutamate 2/3 receptor binding in the perigenual anterior cingulate cortex of Cloninger type 2 alcoholics: a whole-hemisphere autoradiography study. ALCOHOL AND ALCOHOLISM 50 (2015) 1: 62-67. 2014
• Kupila Jukka, Kärkkäinen Olli, Laukkanen Virpi, Häkkinen Merja, Kautiainen Hannu, Tiihonen Jari, Storvik Markus. 2014. [3H]Ifenprodil binding in post-mortem brains of Cloninger type 1 and 2 alcoholics: A whole-hemisphere autoradiography study. PSYCHIATRY RESEARCH: NEUROIMAGING 2015; 231 3: 197-201. 2014
• Kankuri Esko, Mervaala Elina, Storvik Markus, Ahola Aija-Maria, Levijoki Jouko, Muller Dominik N, Finckenberg Piet, Mervaala Eero. 2014. Exacerbation of acute kidney injury by bone marrow stromal cells from rats with persistent renin-angiotensin system activation. CLINICAL SCIENCE (LONDON) 2015; 128 11: 735-747. 2014
• Huuskonen Pasi, Myllynen Päivi, Storvik Markus, Pasanen Markku. 2013. The effects of aflatoxin B1 on transporters and steroid metabolizing enzymes in JEG-3 cells. TOXICOLOGY LETTERS 218: 200-206. 2013
• Kärkkäinen Olli K, Lehtonen Marko, Laukkanen Virpi, Tupala Erkki, Hyytiä Petri, Kautiainen Hannu, Tiihonen Jari, Callaway JC, Storvik Markus. 2013. Endogenous cannabinoids in amygdala and hippocampus in post-mortem brains of Cloninger type 1 and 2 alcoholics. ALCOHOL 47: 399-403. 2013
• Kärkkäinen Olli, Kupila Jukka, Häkkinen Merja, Laukkanen Virpi, Tupala Erkki, Kautiainen Hannu, Tiihonen Jari, Storvik Markus. 2013. AMPA receptors in post-mortem brains of Cloninger type 1 and 2 alcoholics: A whole-hemisphere autoradiography study. PSYCHIATRY RESEARCH: NEUROIMAGING 214: 429-434. 2013
• Laukkanen Virpi, Storvik Markus, Häkkinen Merja, Akamine Yumiko, Tupala Erkki, Virkkunen Matti, Tiihonen Jari. 2013. Decreased GABA(A) benzodiazepine binding site densities in postmortem brains of Cloninger type 1 and 2 alcoholics. ALCOHOL 47: 103-108. 2013
• Tenorio-Laranga Jofre, Männistö Pekka T, Storvik Markus, Van der Veken Pieter, García-Horsman J. Arturo. 2012. Four day inhibition of prolyl oligopeptidase causes significant changes in the peptidome of rat brain, liver and kidney. BIOCHIMIE 94: 1849-1859. 2012
• Storvik Markus, Häkkinen Merja, Tupala Erkki, Tiihonen Jari. 2012. Whole-hemisphere autoradiography of 5-HT₁B receptor densities in postmortem alcoholic brains. PSYCHIATRY RESEARCH: NEUROIMAGING 202: 264-270. 2012
• Kurronen A, Pihlaja R, Pollari E, Kanninen K, Storvik M, Wong G, Koistinaho M, Koistinaho J. 2012. Adult and neonatal astrocytes exhibit diverse gene expression profiles in response to beta amyloid ex vivo. World Journal of Neuroscience 2/2012: 57-67. 2012
• Marttinen Maija, Päivärinta Essi, Storvik Markus, Huikko Laura, Luoma-Halkola Heli, Piironen Vieno, Pajari Anne-Maria, Mutanen Marja. 2012. Plant stanols induce intestinal tumor formation by up-regulating Wnt and EGFR signaling in Apc(Min) mice. JOURNAL OF NUTRITIONAL BIOCHEMISTRY 2013:24: 343-352. 2012
• Kupila Jukka, Kärkkäinen Olli, Laukkanen Virpi, Tupala Erkki, Tiihonen Jari, Storvik Markus. 2012. mGluR1/5 receptor densities in the brains of alcoholic subjects: A whole-hemisphere autoradiography study. PSYCHIATRY RESEARCH: NEUROIMAGING 2013:212: 245-250. 2012
• Aflatoxin B1 up-regulates CYP19A1 in JEG-3 cells. Huuskonen Pasi, Storvik Markus, Kyllönen Taija, Lehtonen Sarka, El-Nezami Hani, Auriola Seppo, Pasanen Markku / 48th Congress of the European Societies of Toxicology (EUROTOX), Stockholm, Sweden, 17th-20th June 2012. 2012. 2012
• Aarnio Vuokko, Lehtonen Marko, Storvik Markus, Callaway James C, Lakso Merja, Wong Garry. 2011. Caenorhabditis elegans mutants predict regulation of fatty acids and endocannabinoids by the CYP-35A gene family. FRONTIERS IN PHARMACOLOGY 2: 1-10. 2011
• Kurki Mitja I, Paananen Jussi, Storvik Markus, Ylä-Herttuala Seppo, Jääskeläinen Juha E, Fraunberg von und zu Mikael, Wong Garry, Pehkonen Petri. 2011. TAFFEL: Independent enrichment analysis of gene sets. BMC BIOINFORMATICS [ONLINE] 12: 171. 2011
• Lehtonen Marko, Storvik Markus, Malinen Hanna, Hyytiä Petri, Lakso Merja, Auriola Seppo, Wong Garry, Callaway James. 2011. Determination of endocannabinoids in nematodes and human brain tissue by liquid chromatography electrospray ionization tandem mass spectrometry JOURNAL OF CHROMATOGRAPHY. B. ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES 879: 677 - 694. 2011
• Moreno-Baylach José, Puttonen Katja, Tenorio-Laranga Jofre, Venäläinen Jarkko, Storvik Markus, Forsberg Markus, García-Horsman Arturo. 2011. Prolyl endopeptidase is involved in cellular signalling in human neuroblastoma SH-SY5Y cells Neurosignals 19: 97 - 109. 2011
• Reisner Kaja, Lehtonen Marko, Storvik Markus, Jantson Tanel, Lakso Merja, Callaway James C, Wong Garry. 2011. Trans fat diet causes decreased brood size and shortened lifespan in Caenorhabditis elegans delta-6-desaturase mutant fat-3. Journal of Biochemical and Molecular Toxicology 25 5: 269-279. 2011
• Storvik Markus, Huuskonen Pasi, Kyllönen Taija, Lehtonen Sarka, El-Nezami Hani, Auriola Seppo, Pasanen Markku. 2011. Aflatoxin B1 - a potential endocrine disruptor - up-regulates CYP19A1 in JEG-3 cells Toxicology letters 202 3: 161 - 167. 2011
• Tauriainen Eveliina, Storvik Markus, Finckenberg Piet, Merasto Saara, Martonen Essi, Pilvi Taru K, Korpela Riitta, Mervaala Eero M. 2011. Skeletal muscle gene expression profile is modified by dietary protein source and calcium during energy restriction. JOURNAL OF NUTRIGENETICS AND NUTRIGENOMICS 4 1: 49-62. 2011
• Vahtola Erik, Storvik Markus, Louhelainen Marjut, Merasto Saara, Lakkisto Päivi, Lakkisto Jarkko, Tikkanen Ilkka, Kaheinen Petri, Levijoki Jouko, Mervaala Eero. 2011. Effects of levosimendan on cardiac gene expression profile and post-infarct cardiac remodelling in diabetic Goto-Kakizaki rats BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY 109: 387-397. 2011
• Aarnio V, Storvik M, Lehtonen M, Asikainen S, Reisner K, Callaway J, Rudgalvyte M, Lakso M & Wong G. 2010. Fatty acid composition and gene expression profiles are altered in aryl hydrocarbon receptor-1 mutant Caenorhabditis elegans. Comparative Biochemistry and Physiology. Part C 151: 318 - 324. 2010
• Lehtonen M, Storvik M, Tupala E, Hyytiä P, Tiihonen J & Callaway JC. 2010. Endogenous cannabinoids in post-mortem brains of Cloninger type 1 and 2 alcoholics. EUROPEAN NEUROPSYCHOPHARMACOLOGY 20: 245 - 252. 2010
• Storvik M, Arguel MJ, Schmieder S, Delerue-Audegond A, Li Q, Qin C, Vital A, Bioulac B, Gross CE, Wong G et al. 2010. Genes regulated in MPTP-treated macaques and human Parkinson's disease suggest a common signature in prefrontal cortex NEUROBIOLOGY OF DISEASE (SAN DIEGO CA) 38: 386-394. 2010
• Storvik M, Häkkinen M, Tupala E, Tiihonen J. 2009. 5-HT1A receptors in the frontal cortical brain areas in Cloninger type 1 and 2 alcoholics measured by whole-hemisphere autoradiography. ALCOHOL AND ALCOHOLISM 44 1: 2-7. 2009
• Asikainen S, Heikkinen L, Wong G, Storvik M. 2008. Functional characterization of endogenous siRNA target genes in Caenorhabditis elegans. BMC GENOMICS [ONLINE:HTTP://WWW.BIOMEDCENTRAL.COM/BMCGENOMICS/] 9 270: 10 s. 2008
• Huuskonen P, Storvik M, Reinisalo M, Honkakoski P, Rysä J, Hakkola J, Pasanen M. 2008. Microarray analysis of the global alterations in the gene expression in the placentas from cigarette-smoking mothers. CLINICAL PHARMACOLOGY AND THERAPEUTICS 83: 542-550. 2008
• Pilvi TK, Storvik M, Louhelainen M, Merasto S, Korpela R, Mervaala EM. 2008. Effect of dietary calcium and dairy proteins on the adipose tissue gene expression profile in diet-induced obesity. JOURNAL OF NUTRIGENETICS AND NUTRIGENOMICS 1: 240-251. 2008
• Storvik M, Haukijärvi T, Tupala E, Tiihonen J. 2008. Correlation between the SERT binding densities in hypothalamus and amygdala in Cloninger type 1 and 2 alcoholics. ALCOHOL AND ALCOHOLISM 43 1: 25-30. 2008
• Tupala E, Häkkinen M, Storvik M, Tiihonen J. 2008. Striatal dopaminergic terminals in type 1 and type 2 alcoholics measured with [3H]dihydrotetrabenazine and human whole himisphere autoradiography PSYCHIATRY RESEARCH: NEUROIMAGING 163: 70-75. 2008
• Storvik M, Tiihonen J, Haukijärvi T, Tupala E. 2007. Amygdala serotonin transporters in alcoholics measured by whole hemisphere autoradiography. SYNAPSE 61: 629-636. 2007
• Storvik M. 2004. Molecular Mechanisms of the Effects of Uncompetitive NMDA-antagonist MK-801 on CREB Related Transcription Factors. Kuopion yliopiston julkaisuja G.- A.I. Virtanen -instituutti. 2004
• Marvanová M, Storvik M, Wong G. 2003. Microarray data analysis - applications for studies on gene expression in addiction and human/nonhuman primates: Kotila S, Haataja J, Forsström P-L, Ignatius J, Jukka L, Laine MM, Runeberg N, Råback P, Savolainen V, CSC Report on Scientific Computing 2001-2003.CSC-Scientific Computing. 151-154. 2003
• Storvik M, Lindén A-M, Lakso M, Wong G. 2003. Subunit selective decrease of AMPA and metabotropic glutamate receptor mRNA expression in rat brain by systemic administration of the NMDA receptor blocker MK-801. JOURNAL OF MOLECULAR NEUROSCIENCE 21 1: 29-34. 2003
• Marvanova M, Törönen P, Storvik M, Lakso M, Castrén E, Wong G. 2002. Synexpression analysis of ESTs in the rat brain reveals distinct patterns and potential drug targets MOLECULAR BRAIN RESEARCH 104 2: 176-183. 2002
• Törönen P, Storvik M, Lindén A-M, Kontkanen O, Marvanova M, Lakso M, Castrén E, Wong G. 2002. Expression profiling to understand actions of NMDA/glutamate receptor antagonists in rat brain. NEUROCHEMICAL RESEARCH 27 10: 1205-1216. 2002
• Lindén A-M, Storvik M, Lakso M, Haapasalo A, Lee D, Witkin JM, Sei Y, Castrén E, Wong G. 2001. Increased expression of neuronal Src and tyrosine phosphorylation of NMDA receptors in rat brain after systemic treatment with MK-801. NEUROPHARMACOLOGY 40: 469-481. 2001
• Lindén A-M, Väisänen J, Storvik M, Lakso M, Korpi ER, Wong G, Castrén E. 2001. Uncompetitive antagonists of the N-methyl-D-aspartate (NMDA) receptors alter the mRNA expression of proteins associated with the NMDA receptor complex. BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY 88: 98-105. 2001
• Storvik M, Lindén A-M, Kontkanen O, Lakso M, Castrén E, Wong G. 2000. Induction of cAMP response element modulator (CREM) and inducible cAMP early repressor (ICER) expression in rat brain by uncompetitive N-methyl-D-aspartate receptor antagonists. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 294 1: 52-60. 2000