Matti Uusitupa

Association of omega 3 polyunsaturated fatty acids with incident chronic kidney disease: pooled analysis of 19 cohorts

Ong, Kwok Leung; Marklund, Matti; Huang, Liping; Rye, Kerry-Anne; Hui, Nicholas; Pan, Xiong-Fei; Rebholz, Casey M; Kim, Hyunju; Steffen, Lyn M; van Westing, Anniek C; Geleijnse, Johanna M; Hoogeveen, Ellen K; Chen, Yun-Yu; Chien, Kuo-Liong; Fretts, Amanda M; Lemaitre, Rozenn N; Imamura, Fumiaki; Forouhi, Nita G; Wareham, Nicholas J; Birukov, Anna; Jäger, Susanne; Kuxhaus, Olga; Schulze, Matthias B; de Mello, Vanessa Derenji; Tuomilehto, Jaakko; Uusitupa, Matti; Lindström, Jaana; Tintle, Nathan; . 2023. BMJ. 380:

Combination of Multiple Low-Risk Lifestyle Behaviors and Incident Type 2 Diabetes: A Systematic Review and Dose-Response Meta-analysis of Prospective Cohort Studies

Khan, Tauseef A.; Field, David; Chen, Victoria; Ahmad, Suleman; Mejia, Sonia Blanco; Kahleová, Hana; Rahelić, Dario; Salas-Salvadó, Jordi; Leiter, Lawrence A.; Uusitupa, Matti; Kendall, Cyril W.C.; Sievenpiper, John L.. 2023. Diabetes care. 46: 643-656

Diabeteksen kansallisen ehkäisyhankkeen pitkäaikaiset vaikutukset ja merkitys

Uusitupa, Matti; Saaristo, Timo; Rintamäki, Reeta; Pölönen, Auli; Valtanen, Mikko; Rautio, Nina; Risku, Sari; Länsipuro, Liisa; Hirsso, Päivi; Ahtiainen, Petteri; Saltevo, Juha; Keinänen-Kiukaanniemi, Sirkka; Moilanen, Leena; Lindström, Jaana; Peltonen, Markku; Oksa, Heikki; Tuomilehto, Jaakko . 2023. DIABETES JA LÄÄKÄRI. 52: 9-16

Eating behavior dimensions and 9-year weight loss maintenance: a sub-study of the Finnish Diabetes prevention study

Salmela, Jutta; Konttinen, Hanna; Lappalainen, Raimo; Muotka, Joona; Antikainen, Anne; Lindström, Jaana; Tuomilehto, Jaakko; Uusitupa, Matti; Karhunen, Leila. 2023. International journal of obesity. 47: 564-573

Evidence-based European recommendations for the dietary management of diabetes

The Diabetes and Nutrition Study Group (DNSG) of the European Association for the Study of Diabetes (EASD). 2023. Diabetologia. 66: 965-985

Genome-wide association study and functional characterization identifies candidate genes for insulin-stimulated glucose uptake

Williamson, Alice; Norris, Dougall M.; Yin, Xianyong; Broadaway, K. Alaine; Moxley, Anne H.; Vadlamudi, Swarooparani; Wilson, Emma P.; Jackson, Anne U.; Ahuja, Vasudha; Andersen, Mette K.; Arzumanyan, Zorayr; Bonnycastle, Lori L.; Bornstein, Stefan R.; Bretschneider, Maxi P.; Buchanan, Thomas A.; Chang, Yi-Cheng; Chuang, Lee-Ming; Chung, Ren-Hua; Clausen, Tine D.; Damm, Peter; Delgado, Graciela E.; de Mello, Vanessa D.; Dupuis, Josée; Dwivedi, Om P.; Erdos, Michael R.; Silva, Lilian Fernandes; F. 2023. Nature genetics. 55: 973-983

Lifestyle Intervention Guided by Group and Internet-Based Counseling in the T2D-GENE Trial Supports Its Applicability and Feasibility

Schwab, Ursula; Lankinen, Maria; Uusitupa, Matti; Laakso, Markku. 2023. Nutrients. 15:

Not all very-low-carbohydrate diets are created equal. Reply to Conte C, Camajani E, Lai A, Caprio M [letter]

Reynolds, Andrew N; Kahleova, Hana; Uusitupa, Matti; Hermansen, Kjeld; Aas, Anne Marie; Schwab, Ursula; Lean, Michael EJ; Pfeiffer, Andreas; Salas-Salvadó, Jordi; Mann, Jim I. 2023. Diabetologia. 66: 1754-1755

The effect of vitamin D3 supplementation on atrial fibrillation in generally healthy men and women: the Finnish Vitamin D Trial

Virtanen, Jyrki K; Hantunen, Sari; Lamberg-Allardt, Christel; Manson, JoAnn E; Nurmi, Tarja; Uusitupa, Matti; Voutilainen, Ari; Tuomainen, Tomi-Pekka. 2023. American heart journal. 264: 177-182

Towards Individually Tailored Diets in Prevention and Treatment of Diabetes?

Uusitupa, Matti; Schwab, Ursula. 2023. Nutrients. 15:

Type 2 Diabetes Prevention Programs — From Proof-of-Concept Trials to National Intervention and Beyond

Tuomilehto, Jaakko; Uusitupa, Matti; Gregg, Edward W.; Lindström, Jaana. 2023. Journal of clinical medicine. 12:

Analysis of the SYSDIET Healthy Nordic Diet randomized trial based on metabolic profiling reveal beneficial effects on glucose metabolism and blood lipids

Gürdeniz, Gözde; Uusitupa, Matti; Hermansen, Kjeld; Savolainen, Markku J.; Schwab, Ursula; Kolehmainen, Marjukka; Brader, Lea; Cloetens, Lieselotte; Herzig, Karl-Heinz; Hukkanen, Janne; Rosqvist, Fredrik; Ulven, Stine Marie; Gunnarsdóttir, Ingibjörg; Thorsdottir, Inga; Oresic, Matej; Poutanen, Kaisa S.; Risérus, Ulf; Åkesson, Björn; Dragsted, Lars Ove. 2022. Clinical nutrition. 41: 441-451

Genetic Predictors of Change in Waist Circumference and Waist-to-Hip Ratio With Lifestyle Intervention: The Trans-NIH Consortium for Genetics of Weight Loss Response to Lifestyle Intervention

McCaffery, Jeanne M.; Jablonski, Kathleen A.; Pan, Qing; Astrup, Arne; Revsbech Christiansen, Malene; Corella, Dolores; Corso, Lauren M.L.; Florez, Jose C.; Franks, Paul W.; Gardner, Christopher; Hansen, Torben; Kilpeläinen, Tuomas O.; Knowler, William C.; Lindström, Jaana; Saris, Wim H.M.; Sørensen, Thorkild I.A.; Tuomilehto, Jaakko; Uusitupa, Matti; Wing, Rena R.; Agurs-Collins, Tanya. 2022. Diabetes. 71: 669-676

Indolepropionic Acid, a Gut Bacteria-Produced Tryptophan Metabolite and the Risk of Type 2 Diabetes and Non-Alcoholic Fatty Liver Disease

Sehgal, Ratika; de Mello, Vanessa D.; Männistö, Ville; Lindström, Jaana; Tuomilehto, Jaakko; Pihlajamäki, Jussi; Uusitupa, Matti. 2022. Nutrients. 14:

Longitudinal Branched-Chain Amino Acids, Lifestyle Intervention, and Type 2 Diabetes in the Finnish Diabetes Prevention Study

Kivelä, Jemina; Meinilä, Jelena; Uusitupa, Matti; Tuomilehto, Jaakko; Lindström, Jaana. 2022. Journal of clinical endocrinology and metabolism. 107: 2844-2853

Nordic dietary patterns and cardiometabolic outcomes: a systematic review and meta-analysis of prospective cohort studies and randomised controlled trials

Massara, Paraskevi; Zurbau, Andreea; Glenn, Andrea J; Chiavaroli, Laura; Khan, Tauseef A; Viguiliouk, Effie; Mejia, Sonia Blanco; Comelli, Elena M; Chen, Victoria; Schwab, Ursula; Risérus, Ulf; Uusitupa, Matti; Aas, Anne-Marie; Hermansen, Kjeld; Thorsdottir, Inga; Rahelić, Dario; Kahleová, Hana; Salas-Salvadó, Jordi; Kendall, Cyril WC; Sievenpiper, John L. 2022. Diabetologia. 65: 2011-2031

PUFA ω-3 and ω-6 biomarkers and sleep: a pooled analysis of cohort studies on behalf of the Fatty Acids and Outcomes Research Consortium (FORCE)

Murphy, Rachel A; Tintle, Nathan; Harris, William S; Darvishian, Maryam; Marklund, Matti; Virtanen, Jyrki K; Hantunen, Sari; de Mello, Vanessa D; Tuomilehto, Jaakko; Lindström, Jaana; Bolt, Matthew A; Brouwer, Ingeborg A; Wood, Alexis C; Senn, Mackenzie; Redline, Susan; Tsai, Michael Y; Gudnason, Vilmundur; Eiriksdottir, Gudny; Lindberg, Eva; Shadyab, Aladdin H; Liu, Buyun; Carnethon, Mercedes; Uusitupa, Matti; Djousse, Luc; Risérus, Ulf; Lind, Lars; van Dam, Rob M; Koh, Woon-Puay; Shi, Peilin; . 2022. American journal of clinical nutrition. 115: 864-876

Sources of animal proteins and type 2 diabetes risk – decreasing the consumption of red meat is well grounded

Uusitupa, Matti. 2022. Diabetes research and clinical practice. 191:

Vitamin D supplementation and prevention of cardiovascular disease and cancer in the Finnish Vitamin D Trial: a randomized controlled trial

Virtanen, Jyrki K; Nurmi, Tarja; Aro, Antti; Bertone-Johnson, Elizabeth R; Hyppönen, Elina; Kröger, Heikki; Lamberg-Allardt, Christel; Manson, JoAnn E; Mursu, Jaakko; Mäntyselkä, Pekka; Suominen, Sakari; Uusitupa, Matti; Voutilainen, Ari; Tuomainen, Tomi-Pekka; Hantunen, Sari. 2022. American journal of clinical nutrition. 115: 1300-1310

Diabetes sairautena ja sen ravitsemus- ja muu hoito

Uusitupa, Matti. Teoksessa: Mutanen, Marja; Niinikoski, Harri; Schwab, Ursula; Uusitupa, Matti(toim.) , 2021. Ravitsemustiede (8. uud. painos). s. 426-456. Duodecim

Fruit and Vegetables consumption and Type 2 diabetes prevention

Uusitupa, Matti. 2021. The Global Fruit & Veg Newsletter. : -

Heikentynyt glukoosinsieto, insuliiniresistenssi ja metabolinen oireyhtymä ja niiden ehkäisy

Uusitupa, Matti. Teoksessa: Mutanen, Marja; Niinikoski, Harri; Schwab, Ursula; Uusitupa, Matti(toim.) , 2021. Ravitsemustiede (8. uud. painos). s. 402-403. Duodecim

Long-term outcomes of lifestyle intervention to prevent type 2 diabetes in people at high risk in primary health care

Rintamäki, Reeta; Rautio, Nina; Peltonen, Markku; Jokelainen, Jari; Keinänen-Kiukaanniemi, Sirkka; Oksa, Heikki; Saaristo, Timo; Puolijoki, Hannu; Saltevo, Juha; Tuomilehto, Jaakko; Uusitupa, Matti; Moilanen, Leena. 2021. Primary care diabetes. 15: 444-450

Mitä suomalainen tyypin 2 diabeteksen ehkäisytutkimus DPS on opettanut?

Lindström, Jaana; Uusitupa, Matti; Eriksson, Johan; Ilanne-Parikka, Pirjo; Keinänen-Kiukaanniemi, Sirkka; Tuomilehto, Jaakko. 2021. Duodecim. 137: 2399-2406

Ravitsemustiede

Mutanen, Marja; Niinikoski, Harri; Schwab, Ursula; Uusitupa, Matti. 2021. . 8. uud. painos. Duodecim

Ravitsemustilan arviointi ja ravinnonsaannin tehostaminen

Uusitupa, Matti; Fogelholm; Schwab, Ursula. Teoksessa: Mutanen, Marja; Niinikoski, Harri; Schwab, Ursula; Uusitupa, Matti(toim.) , 2021. Ravitsemustiede (8. uud. painos). s. 293-303. Duodecim

Serum Levels of Plasmalogens and Fatty Acid Metabolites Associate with Retinal Microangiopathy in Participants from the Finnish Diabetes Prevention Study

de Mello, Vanessa Derenji; Selander, Tuomas; Lindström, Jaana; Tuomilehto, Jaakko; Uusitupa, Matti; Kaarniranta, Kai. 2021. Nutrients. 13: 4452

Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability

Mägi, Reedik; Hottenga, Jouke- Jan; Grallert, Harald; Perry, John R. B.; Bouatia-Naji, Nabila; Marullo, Letizia; Rybin, Denis; Jansen, Rick; Min, Josine L.; Dimas, Antigone S.; Ulrich, Anna; Zudina, Liudmila; Gådin, Jesper R.; Jiang, Longda; Faggian, Alessia; Bonnefond, Amélie; Fadista, Joao; Stathopoulou, Maria G.; Isaacs, Aaron; Willems, Sara M et al. [incl. Kuusisto, Johanna; Laakso, Markku; Lakka, Timo, Uusitupa, Matti]. 2021. Nature communications. 12: 24

Sydämen vajaatoiminta

Uusitupa, Matti. Teoksessa: Mutanen, Marja; Niinikoski, Harri; Schwab, Ursula; Uusitupa, Matti(toim.) , 2021. Ravitsemustiede (8. uud. painos). s. 533-535. Duodecim

Sydän- ja verisuonitautien ehkäisy ja riskitekijöiden lääkkeetön hoito

Schwab, Ursula; Uusitupa, Matti; Niinikoski, Harri. Teoksessa: Mutanen, Marja; Niinikoski, Harri; Schwab, Ursula; Uusitupa, Matti(toim.) , 2021. Ravitsemustiede (8. uud. painos). s. 373-397. Duodecim

Syömisen säätely

Uusitupa, Matti; Karhunen, Leila. Teoksessa: Mutanen, Marja; Niinikoski, Harri; Schwab, Ursula; Uusitupa, Matti(toim.) , 2021. Ravitsemustiede (8. uud. painos). s. 404-405. Duodecim

Tehohoitopotilaan ravitsemushoito

Ala-Kokko, Tero; Bäcklund, Minna; Schwab, Ursula; Niinikoski, Harri; Uusitupa, Matti. Teoksessa: Mutanen, Marja; Niinikoski, Harri; Schwab, Ursula; Uusitupa, Matti(toim.) , 2021. Ravitsemustiede (8. uud. painos). s. 606-620. Duodecim

The trans-ancestral genomic architecture of glycemic traits

Chen, J; Spracklen, CN; Marenne, G; Varshney, A; Corbin, LJ; Luan, J; Willems, SM; Wu, Y; Zhang, X; Horikoshi, M; Boutin, TS; Mägi, R; Waage, J; Li-Gao, R; Chan, KHK; Yao, J; Anasanti, MD; Chu, AY; Claringbould, A; Heikkinen, J; et al. [incl. Kuulasmaa, T; Kuusisto, J; Laakso, M; Lakka, T; Uusitupa, M; Vangipurapu, J]. 2021. Nature genetics. 53: 840-860

Tyypin 2 diabeteksen Käypä hoito -suosituksessa laihduttaminen jää sivuosaan

Mustajoki, Pertti; Uusitupa, Matti. 2021. Duodecim. 137: 654 - 655

Tyypin 2 diabeteksen ehkäisy

Uusitupa, Matti. Teoksessa: Mutanen, Marja; Niinikoski, Harri; Schwab, Ursula; Uusitupa, Matti(toim.) , 2021. Ravitsemustiede (8. uud. painos). s. 400-402. Duodecim

Uudet tutkimusmenetelmät ja yksilöity ravitsemushoito

Uusitupa, Matti. Teoksessa: Mutanen, Marja; Niinikoski, Harri; Schwab, Ursula; Uusitupa, Matti(toim.) , 2021. Ravitsemustiede (8. uud. painos). s. 312-323. Duodecim

Covid-19-tauti muistuttaa lihavuuden hoidon merkityksestä

Uusitupa, Matti; Mustajoki, Pertti; Pietiläinen, Kirsi. 2020. Lääkärilehti. 75: 1736

Divergent pathologies and treatment options for diabetic neuropathies

Uusitupa, Matti; Niskanen, Leo; Laitinen, Tomi. 2020. Diabetologia. 63: 1947-1948

Evolving Nutritional Therapy for Diabetes Mellitus

Uusitupa, Matti; Schwab, Ursula. 2020. Nutrients. 12: 423

Fatty acids in the de novo lipogenesis pathway and incidence of type 2 diabetes: A pooled analysis of prospective cohort studies

Imamura, Fumiaki; Fretts, Amanda M; Marklund, Matti; Ardisson Korat, Andres V; Yang, Wei-Sin; Lankinen, Maria; Qureshi, Waqas; Helmer, Catherine; Chen, Tzu-An; Virtanen, Jyrki K; Wong, Kerry; Bassett, Julie K; Murphy, Rachel; Tintle, Nathan; Yu, Chaoyu Ian; Brouwer, Ingeborg A; Chien, Kuo-Liong; Chen, Yun-Yu; Wood, Alexis C; Del Gobbo, Liana C et al [incl. Laakso, Markku; Tuomainen, Tomi-Pekka; Uusitupa, Matti]. 2020. PLoS medicine. 17: e1003102

Metformin and risk of Alzheimer's disease among community-dwelling people with diabetes: a national case-control study

Sluggett, JK; Koponen, M; Bell, JS; Taipale, H; Tanskanen, A; Tiihonen, J; Uusitupa, M; Tolppanen, AM; Hartikainen, S. 2020. Journal of clinical endocrinology and metabolism. 105: dgz234

The Effects of Different Quantities and Qualities of Protein Intake in People With Diabetes Mellitus

Pfeiffer, AFH; Pedersen, E; Schwab, U; Risérus, U; Aas, AM; Uusitupa, M; Thanopoulou, A; Kendall, C; Sievenpiper, JL; Kahleová, H; Rahélic, D; Salas-Salvadó, J; Gebauer, S; Hermansen, K. 2020. Nutrients. 12: 365

Tyypin 2 diabetesepidemia odottaa edelleen ratkaisuja

Uusitupa, Matti. 2020. Lääkärilehti. 75: 740

An Isocaloric Nordic Diet Modulates RELA and TNFRSF1A Gene Expression in Peripheral Blood Mononuclear Cells in Individuals with Metabolic Syndrome-A SYSDIET Sub-Study

Ulven, SM; Holven, KB; Rundblad, A; Myhrstad, MCW; Leder, L; Dahlman, I; Mello, VD; Schwab, U; Carlberg, C; Pihlajamäki, J; Hermansen, K; Dragsted, LO; Gunnarsdottir, I; Cloetens, L; Åkesson, B; Rosqvist, F; Hukkanen, J; Herzig, KH; Savolainen, MJ; Risérus, U; et al. [incl. Uusitupa, M]. 2019. Nutrients. 11: 2932

Associations of circulating very-long-chain saturated fatty acids and incident type 2 diabetes: a pooled analysis of prospective cohort studies

Fretts, AM; Imamura, F; Marklund, M; Micha, R; Wu, JHY; Murphy, RA; Chien, KL; McKnight, B; Tintle, N; Forouhi, NG; Qureshi, WT; Virtanen, JK; Wong, K; Wood, AC; Lankinen, M; Rajaobelina, K; Harris, TB; et al (incl; Laakso, M; Uusitupa, M; Voutilainen, S). 2019. American journal of clinical nutrition. 109: 1216-1223

Biomarkers of Dietary Omega-6 Fatty Acids and Incident Cardiovascular Disease and Mortality: An Individual-Level Pooled Analysis of 30 Cohort Studies

Marklund, M; Wu, JHY; Imamura,;F, Del Gobbo, LC; Fretts, A; de Goede, J; Shi, P; Tintle, N; Wennberg, M; Aslibekyan, S; Chen, TA; de Oliveira Otto, MC; Hirakawa, Y; Eriksen, HH; Kröger, J; Jaguzzi, F; Lankinen, M; Murphy, Rachel A; Prem, Kiesha; Samieri, Cécilia; et al. (incl. Uusitupa, M; Mursu J; Laakso, M; Virtanen, J). 2019. Circulation. 139: 2422-2436

Good news from the Da Qing Diabetes Prevention Outcome Study-healthy lifestyles result in long-term cardiovascular benefits

Uusitupa, Matti. 2019. Annals of translational medicine. 7: S368

Healthy Nordic Diet Modulates the Expression of Genes Related to Mitochondrial Function and Immune Response in Peripheral Blood Mononuclear Cells from Subjects with the Metabolic Syndrome - A SYSDIET Sub-Study

Myhrstad, MC; de Mello, VD; Dahlman, I; Kolehmainen, M; Paananen, J; Rundblad, A; Carlberg, C; Olstad, OK; Pihlajamäki, J; Holven, KB; Hermansen, K; Dragsted, LO; Gunnarsdottir, I; Cloetens, L; Storm, MU; Åkesson, B; Rosqvist, F; Hukkanen, J; et al. (incl. Schwab, U; Uusitupa, M). 2019. Molecular nutrition and food research. 63: 1801405

Kalaöljyt ja sydäntautien ehkäisy

Uusitupa, Matti; Schwab, Ursula. 2019. Duodecim. 135: 905-907

Life Style Intervention Improves Retinopathy Status - The Finnish Diabetes Prevention Study

Aro, A; Kauppinen, A; Kivinen, N; Selander, T; Kinnunen, K; Tuomilehto, J; Keinänen-Kiukaanniemi, S; Lindström, J; Uusitupa, M; Kaarniranta, K. 2019. Nutrients. 11: 1691

Nordic Diet and Inflammation - A Review of Observational and Intervention Studies

Lankinen, Maria; Uusitupa, Matti; Schwab, Ursula. 2019. Nutrients. 11: 1369

Prevention of Type 2 Diabetes by Lifestyle Changes: A Systematic Review and Meta-Analysis

Uusitupa, M; Khan, TA; Viguiliouk, E; Kahleova, H; Rivellese, AA; Hermansen, K; Pfeiffer, A; Thanopoulou, A; Salas-Salvadó, J; Schwab, U; Sievenpiper, JL. 2019. Nutrients. 11: 2611

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

Justice, AE; Karaderi, T; Highland, HM; Young, KL; Graff, M; Lu, Y; Turcot, V; Auer, PL; Fine, RS; Guo, X; Schurmann, C; Lempradl, A; Marouli, E; Mahajan, A; Winkler, TW; Locke, AE; Medina-Gomez, C; Esko, T; Vedantam, S; Giri, A; Lo, KS; et al. (Incl. Kuusisto, Johanna; Laakso, Markku; Lakko, Timo; Uusitupa, Matti; Vanhala, Mauno). 2019. Nature genetics. 51: 452-469

Quantitative assessment of betainized compounds and associations with dietary and metabolic biomarkers in the randomized study of the healthy Nordic diet (SYSDIET)

Tuomainen, M; Kärkkäinen, O; Leppänen, J; Auriola, S; Lehtonen, M; Savolainen, MJ; Hermansen, K; Risérus, U; Åkesson, B; Thorsdottir, I; Kolehmainen, M; Uusitupa, M; Poutanen, K; Schwab, U; Hanhineva, K. 2019. American journal of clinical nutrition. 110: 1108-1118

Associations of serum indolepropionic acid, a gut microbiota metabolite, with type 2 diabetes and low-grade inflammation in high-risk individuals

Tuomainen, Marjo; Lindström, Jaana; Lehtonen, Marko; Auriola, Seppo; Pihlajamäki, Jussi; Peltonen, Markku; Tuomilehto, Jaakko; Uusitupa, Matti; de Mello, Vanessa D; Hanhineva, Kati. 2018. Nutrition and diabetes. 8: 35

Diets rich in whole grains increase betainized compounds associated with glucose metabolism

Kärkkäinen, O; Lankinen, MA; Vitale, M; Jokkala, J; Leppänen, J; Koistinen, V; Lehtonen, M; Giacco, R; Rosa-Sibakov, N; Micard, V; Rivellese, AAA; Schwab, U; Mykkänen, H; Uusitupa, M; Kolehmainen, M; Riccardi, G; Poutanen, K; Auriola, S; Hanhineva, K. 2018. American journal of clinical nutrition. 108: 971-979

Early fecal microbiota composition in children who later develop celiac disease and associated autoimmunity

Rintala, A; Riikonen, I; Toivonen, A; Pietilä, S; Munukka, E; Pursiheimo, JP; Elo, LL; Arikoski, P; Luopajärvi, K; Schwab, U; Uusitupa, M; Heinonen, S; Savilahti, E; Eerola, E; Ilonen, J. 2018. Scandinavian journal of gastroenterology. 53: 403-409

Fatty acid biomarkers of dairy fat consumption and incidence of type 2 diabetes: A pooled analysis of prospective cohort studies

Imamura, F; Fretts, A; Marklund, M; Ardisson Korat, AV; Yang, WS; Lankinen, M; Qureshi, W; Helmer, C; Chen, TA; Wong, K; Bassett, JK; Murphy, R; Tintle, N; Yu, CI; Brouwer, IA; Chien, KL; Frazier-Wood, AC; Del Gobbo, LC; Djoussé, L; Geleijnse, JM; et al (incl. Lankinen, Maria; Laakso, Markku; Uusitupa, Matti). 2018. PLoS medicine. 15: e100267

Genes and Dietary Fatty Acids in Regulation of Fatty Acid Composition of Plasma and Erythrocyte Membrane

Lankinen, Maria; Uusitupa, Matti; Schwab, Ursula. 2018. Nutrients. 10: 1785

Keinotekoiset makeutteet

Uusitupa, Matti; Schwab, Ursula. 2018. Lääkärilehti. 73: 926-930

Prevention of type 2 diabetes - success story that is waiting for next steps

Uusitupa, Matti; Lindström, Jaana; Tuomilehto, Jaakko. 2018. European journal of clinical nutrition. 72: 1260-1266

Remission of type 2 diabetes : mission not impossible

Uusitupa, Matti. 2018. The Lancet. 391: 515-516

Serum Adiponectin/Ferritin Ratio in Relation to the Risk of Type 2 diabetes and Insulin Sensitivity

Aregbesola, A; de Mello, VDF; Lindström, J; Voutilainen, S; Virtanen, JK; Keinänen-Kiukaanniemi, S; Tuomainen, TP; Tuomilehto, J; Uusitupa, M. 2018. Diabetes research and clinical practice. 141: 264-274

Susceptibility of low-density lipoprotein particles to aggregate depends on particle lipidome, is modifiable, and associates with future cardiovascular deaths

Ruuth, M; Nguyen, SD; Vihervaara, T; Hilvo, M; Laajala, TD; Kondadi, PK; Gisterå, A; Lähteenmäki, H; Kittilä, T; Huusko, J; Uusitupa, M; Schwab, U; Savolainen, MJ; Sinisalo, J; Lokki, ML; Nieminen, MS; Jula, A; Perola, M; Ylä-Herttula, S; Rudel, L; et al.. 2018. European heart journal. 39: 2562-2573

Varhainen laihdutus voi kääntää tyypin 2 diabeteksen remissioon

Uusitupa, Matti; Mustajoki, Pertti. 2018. Lääkärilehti. 73: 825-825a

A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk

Manning A, Highland HM, Gasser J, Sim X, Tukiainen T, Fontanillas P, Grarup N, Rivas MA, Mahajan A, Locke AE, Cingolani P, Pers TH, Viñuela A, Brown AA, Wu Y, Flannick J, Fuchsberger C, Gamazon ER, Gaulton KJ, Im HK et al. (incl. Lakka Timo, Kuulasmaa Teemu, Laakso Markku, Uusitupa Matti). 2017. Diabetes. 66: 2019-2032

Alterations in fatty acid metabolism in response to obesity surgery combined with dietary counseling

Walle P, Takkunen M, Männistö V, Vaittinen M, Käkelä P, Ågren J, Schwab U, Lindström J, Tuomilehto J, Uusitupa M, Pihlajamäki J. 2017. Nutrition and diabetes. 7: e285

Fasting serum hippuric acid is elevated after bilberry (Vaccinium myrtillus) consumption and associates with improvement of fasting glucose levels and insulin secretion in persons at high risk of developing type 2 diabetes

de Mello VD, Lankinen MA, Lindström J, Puupponen-Pimiä R, Laaksonen DE, Pihlajamäki J, Lehtonen M, Uusitupa M, Tuomilehto J, Kolehmainen M, Törrönen R, Hanhineva K. 2017. Molecular nutrition and food research. 61: 1700019

Indolepropionic acid and novel lipid metabolites are associated with a lower risk of type 2 diabetes in the Finnish Diabetes Prevention Study

de Mello VD, Paananen J, Lindstrom J, Lankinen MA, Shi L, Kuusisto J, Pihlajamaki J, Auriola S, Lehtonen M, Rolandsson O, Bergdahl IA, Nordin E, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Landberg R, Eriksson JG, Tuomilehto J, Hanhineva K, Uusitupa M. 2017. Scientific reports. 7: 46337

Instability of LDL particles predicts future cardiovascular deaths

Ruuth M, Nguyen SD, Vihervaara T, Hilvo M, Laajala TD, Kondadi PK, Anton G, Huusko J, Uusitupa M, Schwab U, Lawrence R, Ketelhuth D, Laaksonen R, Baumann M, Aittokallio T, Jauhiainen M, Jan B, Williams KJ, Kovanen P, Öörni K. 2017. Atherosclerosis

Painopiste preventioon!

Uusitupa Matti, Rautalahti Matti, Vartiainen Erkki. 2017. Duodecim. 133: 1125-1126

Potkiiko SOTE myös liikkumaan

Uusitupa Matti. 2017. Liikunta ja tiede. 54: 42-44

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

Turcot V, Lu Y, Highland HM, Schurmann C, Justice AE, Fine RS, Bradfield JP, Esko T, Giri A, Graff M, Guo X, Hendricks AE, Karaderi T, Lempradl A, Locke AE, Mahajan A, Marouli E, Sivapalaratnam S, Young KL, Alfred T et al. (incl. Laakso Markku, Lakka Timo, Uusitupa Matti). 2017. Nature genetics. 50; 2018: 26-41

A Healthy Nordic Diet Alters the Plasma Lipidomic Profile in Adults with Features of Metabolic Syndrome in a Multicenter Randomized Dietary Intervention

Lankinen Maria, Schwab Ursula, Kolehmainen Marjukka, Paananen Jussi, Nygren Heli, Seppänen-Laakso Tuulikki, Poutanen Kaisa, Hyötyläinen Tuulia, Risérus Ulf, Savolainen Markku J, Hukkanen Janne, Brader Lea, Marklund Matti, Rosqvist Fredrik, Hermansen Kjeld, Cloetens Lieselotte, Önning Gunilla, Thorsdottir Inga, Gunnarsdottir Ingibjork, Åkesson Björn et al. 2016. Journal of nutrition. 146: 662-672

A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape

Ried JS, Jeff M J, Chu AY, Bragg-Gresham JL, van Dongen J, Huffman JE, Ahluwalia TS, Cadby G, Eklund N, Eriksson J, Esko T, Feitosa MF, Goel A, Gorski M, Hayward C, Heard-Costa NL, Jackson AU, Jokinen E, Kanoni S, Kristiansson K et al. 2016. Nature communications. 7: 13357

Association of long-term dietary fat intake, exercise, and weight with later cognitive function in the Finnish Diabetes Prevention Study

Lehtisalo J, Lindström J, Ngandu T, Kivipelto M, Ahtiluoto S, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Eriksson JG, Uusitupa M, Tuomilehto J, Luchsinger J. 2016. Journal of nutrition health and aging. 20: 146-154

Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

Winkler Thomas W, Justice Anne E, Graff Mariaelisa, Barata Llilda, Feitosa Mary F, Chu Su, Czajkowski Jacek, Esko Tõnu, Fall Tove, Kilpeläinen Tuomas O, Lu Yingchang, Mägi Reedik, Mihailov Evelin, Pers Tune H, Rüeger Sina, Teumer Alexander, Ehret Georg B, Ferreira Teresa, Heard-Costa Nancy L, Karjalainen Juha et al. 2016. PLoS genetics. 12: e1006166

Effects of a healthy Nordic diet on gene expression changes in peripheral blood mononuclear cells in response to an oral glucose tolerance test in subjects with metabolic syndrome: a SYSDIET sub-study

Leder Lena, Kolehmainen Marjukka, Narverud Ingunn, Dahlman Ingrid, Myhrstad Mari CW, de Mello Vanessa D, Paananen Jussi, Carlberg Castren, Schwab Ursula, Herzig Karl-Heinz, Cloetens Lieselotte, Storm Matilda Ulmius, Hukkanen Janne, Savolainen Markku J, Rosqvist Fredrik, Hermansen Kjeld, Dragsted Lars O, Gunnarsdottir Ingibjörk, Thorsdottir Inga, Risérus Ulf et al.. 2016. Genes and nutrition. 11: 1-13

Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index

Hinney A, Kesselmeier M, Jall S, Volckmar AL, Föcker M, Antel J, Heid IM, Winkler TW, Grant SF, Guo Y, Bergen AW, Kaye W, Berrettini W, Hakonarson H, Herpertz-Dahlmann B, de Zwaan M, Herzog W, Ehrlich S, Zipfel S, Egberts KM et al., GCAN, WTCCC3, EGG, GIANT, Price Foundation Collaborative Group, Children's Hospital of Philadelphia/Price Foundation. 2016. Molecular psychiatry. 2017; 22: 192-201

FTO genotype and weight loss: systematic review and meta-analysis of 9563 individual participant data from eight randomised controlled trials

Livingstone KM, Celis-Morales C, Papandonatos GD, Erar B, Florez JC, Jablonski KA, Razquin C, Marti A, Heianza Y, Huang T, Sacks FM, Svendstrup M, Sui X, Church TS, Jääskeläinen T, Lindström J, Tuomilehto J, Uusitupa M, Rankinen T, Saris WH et al.. 2016. BMJ. 354: i4707

Following in the Footsteps of the North Karelia Project: Prevention of Type 2 Diabetes

Lindström Jaana, Uusitupa Matti, Tuomilehto Jaakko, Peltonen Markku. 2016. Global heart. 11: 223-228

Hälsofrämjande nordiska kostvanor - senaste framstegen och framtida forskningsutmaningar

Uusitupa Matti. 2016. Nordisk Nutrition. : 27-30

Lifestyle changes and cardiovascular risk reduction in diabetes

Uusitupa Matti. 2016. The Lancet Diabetes & Endocrinology. 4: 877-878

Liikuntalääketiede nyt!

Uusitupa, Matti. 2016. Liikunta ja tiede. 53: 83

Liikuntalääketieteen yhteiskunnallisen merkityksen ja liikuntalääketieteen keskusten toiminnan arviointi (2006 - 2016)

Uusitupa Matti. 2016. Valtion liikuntaneuvoston julkaisuja. .

Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease

Zanoni Paolo, Khetarpal Sumeet A, Larach Daniel B, Hancock-Cerutti William F, Millar John S, Cuchel Marina, DerOhannessian Stephanie, Kontush Anatol, Surendran Praveen, Saleheen Danish, Trompet Stella, Jukema J Wouter, De Craen Anton, Deloukas Panos, Sattar Naveed, Ford Ian, Packard Chris, Majumder Abdullah al Shafi , Alam Dewan S, Di Angelantonio Emanuele et al. 2016. Science. 351: 1166-1171

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

Ehret GB, Ferreira T, Chasman DI, Jackson AU, Schmidt EM, Johnson T, Thorleifsson G, Luan J, Donnelly LA, Kanoni S, Petersen AK, Pihur V, Strawbridge RJ, Shungin D, Hughes MF, Meirelles O, Kaakinen M, Bouatia-Naji N, Kristiansson K, Shah S et al.. 2016. Nature genetics. 48: 1171-1184

Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

Surendran P, Drenos F, Young R, Warren H, Cook JP, Manning AK, Grarup N, Sim X, Barnes DR, Witkowska K, Staley JR, Tragante V, Tukiainen T, Yaghootkar H, Masca N, Freitag DF, Ferreira T, Giannakopoulou O, Tinker A, Harakalova M et al. 2016. Nature genetics. 48: 1151-1161

Alkylresorcinols in adipose tissue biopsies as biomarkers of whole-grain intake: an exploratory study of responsiveness to advised intake over 12 weeks

Wu H, Kolehmainen M, Mykkänen H, Poutanen K, Uusitupa M, Schwab U, Wolk A, Landberg R. 2015. European journal of clinical nutrition. 69: 1244-1248

Biological interpretation of genome-wide association studies using predicted gene functions

Pers Tune H, Karjalainen Juha M, Chan Yingleong, Westra Harm-Jan, Wood Andrew R, Yang Jian, Lui Julian C, Vedantam Sailaja, Gustafsson Stefan, Esko Tonu, Frayling Tim, Speliotes Elizabeth K, Genetic Investigation of ANthropometric Traits (GIANT) Consortium (incl. Johanna Kuusisto, Markku Laakso, Timo Lakka, Matti Uusitupa), Boehnke Michael, Raychaudhuri Soumya, Fehrmann Rudolf SN, Hirschhorn Joel N, Franke Lude. 2015. Nature communications. 6: 5890

CMPF Does Not Associate with Impaired Glucose Metabolism in Individuals with Features of Metabolic Syndrome

Lankinen Maria A., Hanhineva Kati, Kolehmainen Marjukka, Lehtonen Marko, Auriola Seppo, Mykkänen Hannu, Poutanen Kaisa, Schwab Ursula, Uusitupa Matti. 2015. PLoS ONE. 10: e0124379

Changes in glucose metabolism in people with different glucose metabolism disorders at baseline: follow-up results of a Finnish national diabetes prevention programme

Rautio N, Jokelainen J, Oksa H, Saaristo T, Peltonen M, Puolijoki H, Tuomilehto J, Vanhala M, Moilanen L, Uusitupa M, Keinänen-Kiukaanniemi S. 2015. Diabetic medicine. [epub ahead of print 8 May 2015]: -

Cognition in the Finnish Diabetes Prevention Study

Luchsinger José A, Lehtisalo Jenni, Lindström Jaana, Ngandu Tiia, Kivipelto Miia, Ahtiluoto Satu, Ilanne-Parikka Pirjo, Keinänen-Kiukaanniemi Sirkka, Eriksson Johan G, Uusitupa Matti, Tuomilehto Jaakko, for the Finnish Diabetes Prevention Study (DPS). 2015. Diabetes research and clinical practice. 108: e63-e66

Development of gliadin-specific immune responses in children with HLA-associated genetic risk for celiac disease

Lammi Anne, Arikoski Pekka, Hakulinen Arja, Schwab Ursula, Uusitupa Matti, Heinonen Seppo, Savilahti Erkki, Kinnunen Tuure, Ilonen Jorma. 2015. Scandinavian journal of gastroenterology. 2016; 51: 168-177

Diabetes, glycaemia, and cognition - a secondary analysis of the Finnish Diabetes Prevention Study

Lehtisalo Jenni, Lindström Jaana, Ngandu Tiia, Kivipelto Miia, Ahtiluoto Satu, Ilanne-Parikka Pirjo, Keinänen-Kiukaanniemi Sirkka, Eriksson Johan G., Uusitupa Matti, Tuomilehto Jaakko, Luchsinger Jose A, for the Finnish Diabetes Prevention Study (DPS). 2015. Diabetes/metabolism research and reviews. [epub ahead of print 18 AUG 2015]: -

Diet heart controversies - Quality of fat matters

Schwab Ursula, Uusitupa Matti. 2015. Nutrition metabolism and cardiovascular diseases. 25: 617-622

Dietary polyunsaturated fatty acids and the Pro12Ala polymorphisms of PPARG regulate serum lipids through divergent pathways: a randomized crossover clinical trial

Pihlajamäki Jussi, Schwab Ursula, Kaminska Dorota, Ågren Jyrki, Kuusisto Johanna, Kolehmainen Marjukka, Paananen Jussi, Laakso Markku, Uusitupa Matti. 2015. Genes and nutrition. 10: 43

Gene-diet interaction of a common FADS1 variant with marine polyunsaturated fatty acids for fatty acid composition in plasma and erythrocytes among men

Takkunen Markus J, de Mello Vanessa D, Schwab Ursula S, Kuusisto Johanna, Vaittinen Maija, Ågren Jyrki J, Laakso Markku, Pihlajamäki Jussi, Uusitupa MI. 2015. Molecular nutrition and food research. 2016; 60: 381-389

Genetic studies of body mass index yield new insights for obesity biology

Locke Adam E, Kahali Bratati, Berndt Sonja I, Justice Anne E, Pers Tune H, Day Felix R, Powell Corey, Vedantam Sailaja, Buchkovich Martin L, Yang Jian, Croteau-Chonka Damien C, Esko Tonu, Fall Tove, Ferreira Teresa, Gustafsson Stefan, Kutalik Zoltán, Luan Jian'an, Mägi Reedik, Randall Joshua C, Winkler Thomas W et al. 2015. Nature. 518: 197-206

Glucose Metabolism Effects of Vitamin D in Prediabetes: the VitDmet Randomized Placebo-Controlled Supplementation Study

Tuomainen Tomi-Pekka, Virtanen Jyrki K, Voutilainen Sari, Nurmi Tarja, Mursu Jaakko, de Mello Vanessa DF, Schwab Ursula, Hakumäki Martti, Pulkki Kari, Uusitupa Matti. 2015. Journal of Diabetes Research. 2015: 8 pages

Identification and functional characterization of G6PC2 coding variants influencing glycemic traits define an effector transcript at the G6PC2-ABCB11 locus

Mahajan Anubha, Sim Xueling, Ng Hui Jin, Manning Alisa, Rivas Manuel A, Highland Heather M, Locke Adam E, Grarup Niels, Im Hae Kyung, Cingolani Pablo, Flannick Jason, Fontanillas Pierre, Fuchsberger Christian, Gaulton Kyle J, Teslovich Tanya M, Rayner N William, Robertson Neil R, Beer Nicola L, Rundle Jana K, Bork-Jensen Jette et al. On Behalf of the T2D-GENES consortium and GoT2D consortium. 2015. PLoS genetics. 11: e1004876

Is the adiposity-associated FTO gene variant related to all-cause mortality independent of adiposity? Meta-analysis of data from 169,551 Caucasian adults

Zimmermann E, Angquist LH, Mirza SS, Zhao JH, Chasman DI, Fischer K, Qi Q, Smith AV, Thinggaard M, Jarczok MN, Nalls MA, Trompet S, Timpson NJ, Schmidt B, Jackson AU, Lyytikäinen LP, Verweij N, Mueller-Nurasyid M, Vikström M et al. 2015. Obesity reviews. 16: 327-340

Longitudinal associations of serum fatty acid composition with type 2 diabetes risk and markers of insulin secretion and sensitivity in the Finnish Diabetes Prevention Study

Takkunen Markus J, Schwab Ursula S, de Mello Vanessa DF, Eriksson Johan G, Lindström Jaana, Tuomilehto Jaakko, Uusitupa Matti IJ, the DPS Study Group. 2015. European journal of nutrition. 2016; 55: 967-979

MFAP5 is Related to Obesity-Associated Adipose Tissue and Extracellular Matrix Remodeling and Inflammation

Vaittinen Maija, Kolehmainen Marjukka, Rydén Mikael, Eskelinen Matti, Wabitsch Martin, Pihlajamäki Jussi, Uusitupa Matti, Pulkkinen Leena. 2015. Obesity. 23: 1371-1378

Markers of cholesterol metabolism as biomarkers in predicting diabetes in the Finnish Diabetes Prevention Study

de Mello VDF, Lindström J, Eriksson JG, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Pihlajamäki J, Tuomilehto J, Uusitupa M. 2015. Nutrition metabolism and cardiovascular diseases. 25: 635-642

National diabetes prevention program (DEHKO): awareness and self-reported lifestyle changes in Finnish middle-aged population

Wikström K, Lindström J, Tuomilehto J, Saaristo TE, Helakorpi S, Korpi-Hyövälti E, Oksa H, Vanhala M, Keinänen-Kiukaanniemi S, Uusitupa M, Peltonen M. 2015. Public health. 129: 210-217

New genetic loci link adipose and insulin biology to body fat distribution

Shungin Dmitry, Winkler Thomas W, Croteau-Chonka Damien C, Ferreira Teresa, Locke Adam E, Mägi Reedik, Strawbridge Rona J, Pers Tune H, Fischer Krista, Justice Anne E, Workalemahu Tsegaselassie, Wu Joseph MW, Buchkovich Martin L, Heard-Costa Nancy L, Roman Tamara S, Drong Alexander W, Song Ci, Gustafsson Stefan, Day Felix R, Esko Tonu et al. 2015. Nature. 518: 187-196

Plasma fatty acids as predictors of glycaemia and type 2 diabetes

Lankinen Maria A, Stancáková Alena, Uusitupa Matti, Ågren Jyrki, Pihlajamäki Jussi, Kuusisto Johanna, Schwab Ursula, Laakso Markku. 2015. Diabetologia. 58: 2533-2544

Relevance of Vitamin D Receptor Target Genes for Monitoring the Vitamin D Responsiveness of Primary Human Cells

Vukic Maja, Neme Antonio, Seuter Sabine, Saksa Noora, de Mello Vanessa DF, Nurmi Tarja, Uusitupa Matti, Tuomainen Tomi-Pekka, Virtanen Jyrki K, Carlberg Carsten. 2015. PLoS ONE. 10: e0124339

Suomalaisen ravitsemustutkimuksen tähtihetkiä

Uusitpa Matti. 2015. Duodecim. 131: 1865-1871

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

Winkler Thomas W, Justice Anne E, Graff Mariaelisa, Barata Llilda, Feitosa Mary F, Chu Su, Czajkowski Jacek, Esko Tõnu, Fall Tove, Kilpeläinen Tuomas O, Lu Yingchang, Mägi Reedik, Mihailov Evelin, Pers Tune H, Rüeger Sina, Teumer Alexander, Ehret Georg B, Ferreira Teresa, Heard-Costa Nancy L, Karjalainen Juha et al. 2015. PLoS genetics. 11: e1005378

A dietary biomarker approach captures compliance and cardiometabolic effects of a healthy nordic diet in individuals with metabolic syndrome

Marklund Matti, Magnusdottir Ola K, Rosqvist Fredrik, Cloetens Lieselotte, Landberg Rikard, Kolehmainen Marjukka, Brader Lea, Hermansen Kjeld, Poutanen Kaisa S, Herzig Karl-Heinz, Hukkanen Janne, Savolainen Markku J, Dragsted Lars O, Schwab Ursula, Paananen Jussi, Uusitupa Matti, Åkesson Björn, Thorsdottir Inga, Risérus Ulf. 2014. Journal of nutrition. 144: 1642-1649

ADAMTS9 locus associates with increased risk of wet AMD

Helisalmi Seppo, Immonen Ilkka, Losonczy Gergely, Resch Miklos D, Benedek Szabolcs, Balogh Istvan, Papp Andras, Berta Andras, Uusitupa Matti, Hiltunen Mikko, Kaarniranta Kai. 2014. Acta ophthalmologica. 2014: 1

Assessment of Body Composition in Subjects with Metabolic Syndrome Comparing Single-Frequency Bioelectrical Impedance Analysis and Bioelectrical Spectroscopy

Cloetens Lieselotte, Johansson-Persson Anna, Helgegren Hannah, Landin-Olsson Mona, Uusitupa Matti, Åkesson Björn, Önning Gunilla. 2014. Metabolic syndrome and related disorders. Epub ahead of print: -

Association of serum 25-hydroxyvitamin D with lifestyle factors and metabolic and cardiovascular disease markers: population-based cross-sectional study (FIN-D2D)

Miettinen Maija E, Kinnunen Leena, Leiviskä Jaana, Keinänen-Kiukaanniemi Sirkka, Korpi-Hyövälti Eeva, Niskanen Leo, Oksa Heikki, Saaristo Timo, Tuomilehto Jaakko, Vanhala Mauno, Uusitupa Matti, Peltonen Markku. 2014. PLoS ONE. 9: e100235

Associations of erythrocyte membrane fatty acids with the concentrations of C-reactive protein, interleukin 1 receptor antagonist and adiponectin in1373 men

Takkunen MJ, de Mello VDF, Schwab US, Ågren JJ, Kuusisto J, Uusitupa MIJ. 2014. Prostaglandins leukotrienes and essential fatty acids. 91: 169-174

Changes in lifestyle modestly reduce the estimated cardiovascular disease risk in one-year follow-up of the Finnish diabetes prevention program (FIN-D2D)

Rautio N, Jokelainen J, Pölönen A, Oksa H, Peltonen M, Vanhala M, Puolijoki H, Moilanen L, Tuomilehto J, Uusitupa M, Keinänen-Kiukaanniemi S, Saaristo T. 2014. European journal of cardiovascular nursing. Epub ahead of print: -

Changes in vitamin D target gene expression in adipose tissue monitor the vitamin D response of human individuals

Ryynänen Jussi, Neme Antonio, Tuomainen Tomi-Pekka, Virtanen Jyrki K, Voutilainen Sari, Nurmi Tarja, de Mello Vanessa DF, Uusitupa Matti, Carlberg Carsten. 2014. Molecular nutrition and food research. 58: 2036-2045

DNA methylation in obesity and type 2 diabetes

de Mello Vanessa Derenji Ferreira, Pulkkinen Leena, Lalli Marianne, Kolehmainen Marjukka, Pihlajamäki Jussi, Uusitupa Matti. 2014. Annals of medicine. 46: 103-113

Defining the role of common variation in the genomic and biological architecture of adult human height

Wood Andrew R, Esko Tonu, Yang Jian, Vedantam Sailaja, Pers Tune H, Gustafsson Stefan, Chu Audrey Y, Estrada Karol, Luan Jian'an, Kutalik Zoltán, Amin Najaf, Buchkovich Martin L, Croteau-Chonka Damien C, Day Felix R, Duan Yanan, Fall Tove, Fehrmann Rudolf, Ferreira Teresa, Jackson Anne U, Karjalainen Juha et.al.. 2014. Nature genetics. 46: 1173-86

Diabetesepidemia on vielä ehkäistävissä

Uusitupa Matti, Lindström Jaana, Tuomilehto Jaakko. 2014. Lääkärilehti. 69: 1454-1455

Dissecting high from low responders in a vitamin D3 intervention study

Saksa Noora, Neme Antonio, Ryynänen Jussi, Uusitupa Matti, de Mello Vanessa DF, Voutilainen Sari, Nurmi Tarja, Virtanen Jyrki K, Tuomainen Tomi-Pekka, Carlberg Carsten. 2014. Journal of steroid biochemistry and molecular biology. Epub ahead of print: -

Effect of the amount and type of dietary fat on cardiometabolic risk factors and risk of developing type-2 diabetes, cardiovascular disease, and cancer: a systematic review

Schwab Ursula, Lauritzen Lotte, Tholstrup Tine, Haldorsson Thorhallur I, Riserus Ulf, Uusitupa Matti, Becker Wulf. 2014. Food and nutrition research. 58: -

Effects of a healthy Nordic diet on plasma 25-hydroxyvitamin D concentration in subjects with metabolic syndrome: a randomized, placebo-controlled trial (SYSDIET)

Brader Lea, Rejnmark Lars, Carlberg Carsten, Schwab Ursula, Kolehmainen Marjukka, Rosqvist Fredrik, Cloetens Lieselotte, Landin-Olsson Mona, Gunnarsdottir Ingibjorg, Poutanen Kaisa S, Herzig Karl-Heinz, Risérus Ulf, Savolainen Markku J, Thorsdottir Inga, Uusitupa Matti, Hermansen Kjeld. 2014. European journal of nutrition. 53: 1123-34

Effects of whole grain, fish and bilberries on serum metabolic profile and lipid transfer protein activities: a randomized trial (Sysdimet)

Lankinen Maria, Kolehmainen Marjukka, Jääskeläinen Tiina, Paananen Jussi, Joukamo Laura, Kangas Antti J, Soininen Pasi, Poutanen Kaisa, Mykkänen Hannu, Gylling Helena, Ore¨ic Matej, Jauhiainen Matti, Ala-Korpela Mika, Uusitupa Matti, Schwab Ursula. 2014. PLoS ONE. 9: e90352

FTO genetic variants, dietary intake and body mass index: insights from 177 330 individuals

Qi Qibin, Kilpeläinen Tuomas O, Downer Mary K, Tanaka Toshiko, Smith Caren E, Sluijs Ivonne, Sonerstedt Emily, Chu Audrey Y, Renström Frida, Lin Xiaochen, Ängquist Lars H, Huang Jinyan, Liu Zhonghua, Li Yanping, Asif Ali Muhammad, Xu Min, Singh Ahluwalia Tarunweer, Boer Jolanda MA, Chen Peng, Daimon Makoto et.al.. 2014. Human molecular genetics. Epub ahead of print: -

Genome-wide Enrichment Analysis between Endometriosis and Obesity-related Traits Reveals Novel Susceptibility Loci

Rahmioglu Nilufer, Macgregor Stuart, Drong Alexander W, Hedman Åsa K, Harris Holly R, Randall Joshua C, Prokopenko Inga, The International EndoGene Consortium (IEC), The GIANT Consortium, Nyholt Dale R, Morris Andrew P, Montgomery Grant W, Missmer Stacey A, Lindgren Cecilia M, Zondervan Krina T. 2014. Human molecular genetics. Epub ahead of print: -

Healthy Nordic diet downregulates the expression of genes involved in inflammation in subcutaneous adipose tissue in individuals with features of the metabolic syndrome

Kolehmainen Marjukka, Ulven Stine M, Paananen Jussi, de Mello Vanessa, Schwab Ursula, Carlberg Carsten, Myhrstad Mari, Pihlajamäki Jussi, Dungner Elisabeth, Sjölin Eva, Gunnarsdottir Ingibjörg, Cloetens Lieselotte, Landin-Olsson Mona, Akesson Björn, Rosqvist Fredrik, Hukkanen Janne, Herzig Karl-Heinz, Dragsted Lars O, Savolainen Markku J, Brader Lea, Hermansen Kjeld, Risérus Ulf, Thorsdottir Inga, Poutanen Kaisa S, Uusitupa Matti, Arner Peter, Dahlman Ingrid. 2014. American journal of clinical nutrition. 101: 228-239

Lifestyle Changes Aiming at Weight Loss Should Always Be Included in the Treatment of Obese Patients with Obstructive Sleep Apnea

Tuomilehto Henri, Uusitupa Matti. 2014. Sleep. 37: 1021

Lifestyle intervention in prevention of type 2 diabetes in women with a history of gestational diabetes mellitus: one-year results of the FIN-D2D project

Rautio Nina, Jokelainen Jari, Korpi-Hyövälti Eeva, Oksa Heikki, Saaristo Timo, Peltonen Markku, Moilanen Leena, Vanhala Mauno, Uusitupa Matti, Tuomilehto Jaakko, Keinänen-Kiukaanniemi Sirkka. 2014. Journal of womens health. 23: 506-12

Nontargeted metabolite profiling discriminates diet-specific biomarkers for consumption of whole grains, fatty fish, and bilberries in a randomized controlled trial

Hanhineva Kati, Lankinen Maria A, Pedret Anna, Schwab Ursula, Kolehmainen Marjukka, Paananen Jussi, de Mello Vanessa, Sola Rosa, Lehtonen Marko, Poutanen Kaisa, Uusitupa Matti, Mykkänen Hannu. 2014. Journal of nutrition. 2015; 145: 7-17

Novel approach identifies SNPs in SLC2A10 and KCNK9 with evidence for parent-of-origin effect on body mass index

Hoggart Clive J, Venturini Giulia, Mangino Massimo, Gomez Felicia, Ascari Giulia, Zhao Jing Hua, Teumer Alexander, Winkler Thomas W, T¨ernikova Natalia, Luan Jian'an, Mihailov Evelin, Ehret Georg B, Zhang Weihua, Lamparter David, Esko Tõnu, Macé Aurelian, Rüeger Sina, Bochud Pierre-Yves, Barcella Matteo, Dauvilliers Yves et al (including Atalay Mustafa, Kuusisto Johanna, Lakka Timo, Yaluri Alena, Laakso Markku, Uusitupa Matti). 2014. PLoS genetics. 10: e1004508

Plasma alkylresorcinols C17:0/C21:0 ratio, a biomarker of relative whole-grain rye intake, is associated to insulin sensitivity: a randomized study

Magnusdottir OK, Landberg R, Gunnarsdottir I, Cloetens L, Åkesson B, Landin-Olsson M, Rosqvist F, Iggman D, Schwab U, Herzig K-H, Savolainen MJ, Brader L, Hermansen K, Kolehmainen M, Poutanen K, Uusitupa M, Thorsdottir I, Risérus U. 2014. European journal of clinical nutrition. 68: 453-458

Primary vitamin D receptor target genes as biomarkers for the vitamin D3 status in the hematopoietic system

Wilfinger Julia, Seuter Sabine, Tuomainen Tomi-Pekka, Virtanen Jyrki K, Voutilainen Sari, Nurmi Tarja, de Mello Vanessa DF, Uusitupa Matti, Carlberg Carsten. 2014. Journal of nutritional biochemistry. 25: 875-884

Quality control and conduct of genome-wide association meta-analyses

Winkler Thomas W, Day Felix R, Croteau-Chonka Damien C, Wood Andrew R, Locke Adam E, Mägi Reedik, Ferreira Teresa, Fall Tove, Graff Mariaelisa, Justice Anne E, Luan Jian'an, Gustafsson Stefan, Randall Joshua C, Vedantam Sailaja, Workalemahu Tsegaselassie, Kilpeläinen Tuomas O, Scherag André, Esko Tonu, Kutalik Zoltán, Heid Iris M, The Genetic Investigation of Anthropometric Traits (GIANT) Consortium et al. (including Atalay Mustafa, Kuusisto Johanna, Laakso Markku, Yaluri Alena). 2014. Nature physics. 9: 1192-1212

Ruokavalio ja lievä tulehdus

Uusitupa Matti, Schwab Ursula. 2014. Duodecim. 130: 9-11

The Association between HbA1c, Fasting Glucose, 1-Hour Glucose and 2-Hour Glucose during an Oral Glucose Tolerance Test and Cardiovascular Disease in Individuals with Elevated Risk for Diabetes

Lind Marcus, Tuomilehto Jaakko, Uusitupa Matti, Nerman Olle, Eriksson Johan, Ilanne-Parikka Pirjo, Keinänen-Kiukaanniemi Sirkka, Peltonen Markku, Pivodic Aldina, Lindström Jaana. 2014. PLoS ONE. 9: e109506

The impact of weight reduction in the prevention of the progression of obstructive sleep apnea: an explanatory analysis of a 5-year observational follow-up trial

Tuomilehto Henri, Seppä Juha, Uusitupa Matti, Peltonen Markku, Martikainen Tarja, Sahlman Johanna, Kokkarinen Jouko, Randell Jukka, Pukkila Matti, Vanninen Esko, Tuomilehto Jaakko, Gylling Helena. 2014. Sleep medicine. 15: 329-335

The prevalence of metabolic syndrome and metabolically healthy obesity in Europe: a collaborative analysis of ten large cohort studies

van Vliet-Ostaptchouk Jana V, Nuotio Marja-Liisa, Slagter Sandra N, Doiron Dany, Fischer Krista, Foco Luisa, Gaye Amadou, Gögele Martin, Heier Margit, Hiekkalinna Tero, Joensuu Anni, Newby Christopher, Pang Chao, Partinen Eemil, Reischl Eva, Schwienbacher Christine, Tammesoo Mari-Liis, Swertz Morris A, Burton Paul, Ferretti Vincent et.al.. 2014. Bmc endocrine disorders. 14: 1-13

Whole grain rye intake, reflected by a biomarker, is associated with favorable blood lipid outcomes in subjects with the metabolic syndrome - a randomized study

Magnusdottir Ola Kally, Landberg Rikard, Gunnarsdottir Ingibjorg, Cloetens Lieselotte, Åkesson Björn, Rosqvist Fredrik, Schwab Ursula, Herzig Karl-Heinz, Hukkanen Janne, Savolainen Markku J, Brader Lea, Hermansen Kjeld, Kolehmainen Marjukka, Poutanen Kaisa, Uusitupa Matti, Risérus Ulf, Thorsdottir Inga. 2014. PLoS ONE. 9: e110827

Adherence to the Nordic Nutrition Recommendations in a Nordic population with metabolic syndrome: high salt consumption and low dietary fibre intake (The SYSDIET study)

Jonsdottir SE, Brader L, Gunnarsdottir I, Magnusdottir OK, Schwab U, Kolehmainen M, Risérus U, Herzig K-H, Cloetens L, Helgegren H, Johansson-Persson A, Hukkanen J, Poutanen K, Uusitupa M, Hermansen K, Thorsdottir I. 2013. Food and nutrition research. 57: 21391

Alkylresorcinols and A-carotene in plasma as dietary biomarkers for healthy nordic diet

Magnusdottir OK, Landberg R, Gunnarsdottir I, Cloetens L, Åkesson B, Önning G, Jonsdottir SE, Rosqvist F, Schwab U, Herzig KH, Savolainen MJ, Brader L, Hermansen K, Kolehmainen M, Poutanen K, Uusitupa M, Thorsdottir I, Risérus U. 2013. Annals of nutrition and metabolism. 63: 459

Association of erythrocyte membrane fatty acids with changes in glycemia and risk of type 2 diabetes

Mahendran Y, Ågren J, Uusitupa M, Cederberg H, Vangipurapu J, Stancakova A, Schwab U, Kuusisto J, Laakso M. 2013. American journal of clinical nutrition. -: -

Common variants associated with plasma triglycerides and risk for coronary artery disease

Do R, Willer CJ, Schmidt EM, Sengupta S, Gao C, Peloso GM, Gustafsson S, Kanoni S, Ganna A, Chen J, Buchkovich ML, Mora S, Beckmann JS, Bragg-Gresham JL, Chang H-Y, Demirkan A, Den Hertog HM, Donnelly LA, Ehret GB, Esko T et.al.. 2013. Nature genetics. 45: 1345-52

D-vitamiinin puutos on yleistä suomalaisessa aikuisväestössä - D2D-väestötutkimus 2007

Miettinen M, Kinnunen L, Keinänen-Kiukaanniemi S, Korpi-Hyövälti E, Niskanen L, Oksa H, Saaristo T, Sundvall J, Tuomilehto J, Vanhala M, Uusitupa M, Peltonen M. 2013. Lääkärilehti. 68: 211-15

Diet, inflammation and prediabetes - impact of quality of diet

Uusitupa M, Schwab U. 2013. Canadian journal of diabetes. 37: 327-331

Dietary fat in relation to erythrocyte fatty acid composition in men

Takkunen M, Ågren J, Kuusisto J, Laakso M, Uusitupa M, Schwab U. 2013. Lipids. 48: 1093-1102

Discovery and refinement of loci associated with lipid levels

Willer CJ, Schmidt EM, Sengupta S, Peloso GM, Gustafsson S, Kanoni S, Ganna A, Chen J, Buchkovich ML, Mora S, Beckmann JS, Bragg-Gresham JL, Chang H-Y, Demirkan A, Den Hertog HM, Do R, Donnelly LA, Ehret GB, Esko T, Feitosa MF et.al.. 2013. Nature genetics. 45: 1274-1283

Do depressive symptoms have an impact on the effectiveness of lifestyle counseling in prevention of type 2 diabetes? One-year follow-up of FIN-D2D

Rautio N, Jokelainen J, Oksa H, Saaristo T, Moilanen L, Vanhala M, Peltonen M, Korpi-Hyövälti E, Tuomilehto J, Uusitupa M, Timonen M, Keinänen-Kiukaanniemi S. 2013. Primary care diabetes. -: -

Downregulation of CPPED1 expression improves glucose metabolism in vitro in adipocytes

Vaittinen M, Kaminska D, Käkelä P, Eskelinen M, Kolehmainen M, Pihlajamäki J, Uusitupa M, Pulkkinen L. 2013. Diabetes. 62: 3747-3750

Effect of fatty and lean fish intake on lipoprotein subclasses in subjects with coronary heart disease: A controlled trial

Erkkilä AT, Schwab US, Lehto S, de Mello VD, Kangas AJ, Soininen P, Ala-Korpela M, Uusitupa MIJ. 2013. Journal of clinical lipidology. online: -

Effects of an isocaloric healthy Nordic diet on ambulatory blood pressure in metabolic syndrome: a randomized SYSDIET sub-study

Brader L, Uusitupa M, Dragsted LO, Hermansen K. 2013. European journal of clinical nutrition. [Epub ahead of print]: x-x

Effects of an isocaloric healthy Nordic diet on insulin sensitivity, lipid profile and inflammation markers in metabolic syndrome - a randomized study (SYSDIET)

Uusitupa M, Hermansen K, Savolainen MJ, Schwab U, Kolehmainen M, Brader L, Mortensen LS, Cloetens L, Johansson-Persson A, Önning G, Landin-Olsson M, Herzig K-H, Hukkanen J, Rosqvist F, Iggman D, Paananen J, Pulkki KJ, Siloaho M, Dragsted L, Barri T et.al.. 2013. Journal of internal medicine. 274: 52-66

Effects of rye and whole wheat versus refined cereal foods on metabolic risk factors: A randomised controlled two-centre intervention study

Giacco R, Lappi J, Costabile G, Kolehmainen M, Schwab U, Landberg R, Uusitupa M, Poutanen K, Pacini G, Rivellese AA, Riccardi G, Mykkänen H. 2013. Clinical nutrition. online: x-x

Genetic predisposition to obesity and lifestyle factors - the combined analyses of twenty-six known BMI- and fourteen known waist:hip ratio (WHR)-associated variants in the Finnish Diabetes Prevention Study

Jääskeläinen T, Paananen J, Lindström J, Eriksson JG, Tuomilehto J, Uusitupa M. 2013. British journal of nutrition. 110: 1856-1965

Genetic risk score does not predict the outcome of obesity surgery

Käkelä P, Jääskeläinen T, Torpström J, Ilves I, Venesmaa S, Pääkkönen M, Gylling H, Paajanen H, Uusitupa M, Pihlajamäki J. 2013. Obesity surgery. online: -

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

Berndt SI, Gustafsson S, Mägi R, Ganna A, Wheeler E, Feitosa MF, Justice AE, Monda KL, Croteau-Chonka DC, Day FR, Esko T, Fall T, Ferreira T, Gentilini D, Jackson AU, Luan J, Randall JC, Vedantam S, Willer CJ, Winkler TW, et al. (including Atalay M, Kuusisto J, Lakka TA, Stancakova A, Laakso M, Uusitupa M). 2013. Nature genetics. 45: 501-512

Glycerol and fatty acids in serum predict the development of hyperglycemia and type 2 diabetes in Finnish men

Mahendran Yuvaraj, Cederberg Henna, Vangipurapu Jagadish, Kangas Antti J, Soininen Pasi, Kuusisto Johanna, Uusitupa Matti, Ala-Korpela Mika, Laakso Markku. 2013. Diabetes care. 36: 3732-3738

History of medically treated diabetes and risk of Alzheimer disease in a nationwide case-control study

Tolppanen Anna-Maija, Lavikainen Piia, Solomon Alina, Kivipelto Miia, Uusitupa Matti, Soininen Hilkka, Hartikainen Sirpa. 2013. Diabetes care. 36: 2015-2019

Importance of weight loss maintenance and risk prediction in the prevention of type 2 diabetes: analysis of European Diabetes Prevention Study RCT

Penn L, White M, Lindström J, den Boer AT, Blaak E, Eriksson JG, Feskens E, Ilanne-Parikka P, Keinänen-Kiukaanniemi SM, Walker M, Mathers JC, Uusitupa M, Tuomilehto J. 2013. PLoS ONE. 8: e57143

Kohti terveellistä pohjoismaista ruokavaliota

Uusitupa M, Kolehmainen M, Schwab U, Poutanen K. 2013. Kehittyvä Elintarvike. 2: 48-50

Meta-analysis of gene-level associations for rare variants based on single-variant statistics

Hu Y-J, Berndt SI, Gustafsson S, Ganna A, Genetic Investigation of ANthropometric Traits (GIANT) Consortium (including M Atalay, T Lakka, J Kuusisto, M Laakso), Hirschhorn J, North KE, Ingelsson E, Lin D-Y et.al.. 2013. American journal of human genetics. 93: 236-248

Plasma alkylresorcinols reflect important whole-grain components of a healthy nordic diet

Magnusdottir OK, Landberg R, Gunnarsdottir I, Cloetens L, Åkersson B, Önning G, Jonsdottir SE, Rosqvist F, Schwab U, Herzig K-H, Savolainen MJ, Brader L, Hermansen K, Kolehmainen M, Poutanen K, Uusitupa M, Thorsdottir I, Risérus U. 2013. Journal of nutrition. 143: 1383-1390

Predictors of success of a lifestyle intervention in relation to weight loss and improvement in glucose tolerance among individuals at high risk for type 2 diabetes: the FIN-D2D project

Rautio N, Jokelainen J, Saaristo T, Oksa H, Keinänen-Kiukaanniemi S; for the FIN-D2D writing group. 2013. Journal of primary care and community health. 4: 59-66

Rasvainen kala muokkaa HDL-hiukkaskokoa ja lipidipitoisuuksia

Joukamo L, Lankinen M, Schwab U, Soininen P, Kangas AJ, Kolehmainen M, Paananen J, Poutanen K, Mykkänen H, Seppänen-Laakso T, Gylling H, Oresic M, Ala-Korpela M, Uusitupa M. 2013. Duodecim. 129: 2661-70

Serum Omega-3 Polyunsaturated Fatty Acids and Risk of Incident Type 2 Diabetes in Men: The Kuopio Ischaemic Heart Disease Risk Factor Study

Virtanen JK, Mursu J, Voutilainen S, Uusitupa M, Tuomainen T-P. 2013. Diabetes care. 37: 189-196

Sex-stratified Genome-wide Association Studies Including 270,000 Individuals Show Sexual Dimorphism in Genetic Loci for Anthropometric Traits

Randall JC, Winkler TW, Kutalik Z, Berndt SI, Jackson AU, Monda KL, Kilpeläinen TO, Esko T, Mägi R, Li S, Workalemahu T, Feitosa MF, Croteau-Chonka DC, Day FR, Fall T, Ferreira T, Gustafsson S, Locke AE, Mathieson I, Scherag A, et al. (including J Kuusisto, M Laakso, M Atalay, T Lakka). 2013. PLoS genetics. 9: e1003500

The Genetic and Metabolic Determinants of Cardiovascular Complications in Type 2 Diabetes: Recent Insights from Animal Models and Clinical Investigations

Avramoglu RK, Laplante M-A, Quang KL, Deshaies Y, Despres J-P, Larose E, Mathieu P, Poirier P, Perusse L, Vohl M-C, Sweeney G, Ylä-Herttuala S, Laakso M, Uusitupa M, Marette A. 2013. Canadian journal of diabetes. 37: 351-358

Trans-Ethnic Fine-Mapping of Lipid Loci Identifies Population-Specific Signals and Allelic Heterogeneity That Increases the Trait Variance Explained

Wu Y, Waite LL, Jackson AU, Sheu WH, Buyske S, Absher D, Arnett DK, Boerwinkle E, Bonnycastle LL, Carty CL, Cheng I, Cochran B, Croteau-Chonka DC, Dumitrescu L, Eaton CB, Franceschini N, Guo X, Henderson BE, Hindorff LA, Kim E, et al. (including Stancakova A, Kuusisto J, Laakso M, Uusitupa M, Rauramaa R Lakka T.). 2013. PLoS genetics. 9: e1003379

Weight reduction and increased physical activity to prevent the progression of obstructive sleep apnea: a 4-year observational postintervention follow-up of randomized clinical trial

Tuomilehto H, Seppä J, Uusitupa M, Tuomilehto J, Gylling H for the Kuopio Sleep Apnea Group. 2013. JAMA internal medicine. 173: 929-930

A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance

Manning AK, Hivert MF, Scott RA, Grimsby JL, Bouatia-Naji N, Chen H, Rybin D, Liu CT, Bielak LF, Prokopenko I, Amin N, Barnes D, Cadby G, Hottenga JJ, Ingelsson E, Jackson AU, Johnson T, Kanoni S, Ladenvall C, Lagou V et.al.. 2012. Nature genetics. 44: 659-669

Adiponectin receptor 1 gene (ADIPOR1) variant is associated with advanced age-related macular degeneration in Finnish population

Kaarniranta K, Paananen J, Nevalainen T, Sorri I, Seitsonen S, Immonen I, Salminen A, Pulkkinen L, Uusitupa M. 2012. Neuroscience letters. 513: 233-237

Association of the fat mass and obesity-associated (FTO) gene variant (rs9939609) with dietary intake in the Finnish Diabetes Prevention Study

Lappalainen Tiina, Lindström Jaana, Paananen Jussi, Eriksson Johan G, Karhunen Leila, Tuomilehto Jaakko, Uusitupa Matti for the Finnish Diabetes Prevention Study Group. 2012. British journal of nutrition. 108: 1859-65

Conjugated Bile Acids Associate with Altered Rates of Glucose and Lipid Oxidation after Roux-en-Y Gastric Bypass

Simonen M, Dali-Youcef N, Kaminska D, Venesmaa S, Käkelä P, Pääkkönen M, Hallikainen M, Kolehmainen M, Uusitupa M, Moilanen L, Laakso M, Gylling H, Patti ME, Auwerx J, Pihlajamäki J. 2012. Obesity surgery. 22: 1473-1480

Do statins interfere with lifestyle intervention in the prevention of diabetes in primary healthcare? One-year follow-up of the FIN-D2D project

Rautio N, Jokelainen J, Oksa H, Saaristo T, Peltonen M, Vanhala M, Puolijoki H, Moilanen L, Tuomilehto J, Keinänen-Kiukaanniemi S, Uusitupa M. 2012. BMJ open. 2: -

Effects of n-6 PUFAs compared with SFAs on liver fat, lipoproteins, and inflammation in abdominal obesity: a randomized controlled trial

Bjermo H, Iggman D, Kullberg J, Dahlman I, Johansson L, Persson L, Berglund J, Pulkki K, Basu S, Uusitupa M, Rudling M, Arner P, Cederholm T, Ahlström H, Risérus U. 2012. American journal of clinical nutrition. 95: 1003-12

Family history of diabetes and effectiveness of lifestyle counselling on the cardio-metabolic risk profile in individuals at high risk of Type 2 diabetes: 1-year follow-up of the FIN-D2D project

Rautio N, Jokelainen J, Oksa H, Saaristo T, Peltonen M, Puolijoki H, Tuomilehto J, Vanhala M, Moilanen L, Uusitupa M, Keinänen-Kiukaanniemi S. 2012. Diabetic medicine. 29: 207-211

Gene expression of peripheral blood mononuclear cells as a tool in dietary intervention studies: What do we know so far?

de Mello VDF, Kolehmainen M, Schwab U, Pulkkinen L, Uusitupa M. 2012. Molecular nutrition and food research. 56: 1160-1172

How does lifestyle intervention affect depressive symptoms? Results from the Finnish Diabetes Prevention Study

Ruusunen A, Voutilainen S, Karhunen L, Lehto S. M., Tolmunen T, Keinänen-Kiukaanniemi S, Eriksson J, Tuomilehto J, Uusitupa M and Lindström J. 2012. Diabetic medicine. 29: e126-32

Improved lifestyle and decreased diabetes risk over 13 years: long-term follow-up of the randomised Finnish Diabetes Prevention Study (DPS)

Lindström J, Peltonen M, Eriksson JG, Ilanne-Parikka P, Aunola S, Keinänen-Kiukaanniemi S, Uusitupa M, Tuomilehto J. 2012. Diabetologia. online: -

Insulin secretion and its determinants in the progression of impaired glucose tolerance to type 2 diabetes in impaired glucose-tolerant individuals: the finnish diabetes prevention study

de Mello Laaksonen VD, Lindström J, Eriksson J, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Sundvall J, Laakso M, Tuomilehto J, Uusitupa M. 2012. Diabetes care. 35: 211-217

Kehon koostumuksen arviointi

Fogelholm M, Uusitupa M. Teoksessa: Aro A, Mutanen M, Uusitupa M(toim.) , 2012. Ravitsemustiede. s. 196-203. Duodecim

Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways

Scott RA, Lagou V, Welch RP, Wheeler E, Montasser ME, Luan J, Mägi R, Strawbridge RJ, Rehnberg E, Gustafsson S, Kanoni S, Rasmussen-Torvik L, Yengo L, Lecoeur C, Shungin D, Sanna S, Sidore C, Johnson PCD, Jukema JW, Johnson T et.al.. 2012. Nature genetics. 44: 991-1005

Leukocyte Telomere Lenght in the Finnish Diabetes Prevention Study

Hovatta I, de Mello VDF, Kananen L, Lindström J, Eriksson JG, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Peltonen M, Tuomilehto J, Uusitupa M. 2012. PLoS ONE. 7: 1-6

Lihavuuden, tyypin 2 diabeteksen ja metabolisen oireyhtymän ehkäisy

Uusitupa M. Teoksessa: Aro A, Mutanen M, Uusitupa M(toim.) , 2012. Ravitsemustiede. s. 306-309. Duodecim

Lihavuus

Uusitupa M. Teoksessa: Aro A, Mutanen M, Uusitupa M(toim.) , 2012. Ravitsemustiede. s. 347-367. Duodecim

Long-term effects of placental growth on overweight and body composition

Eriksson JG, Gelow J, Thornburg KL, Osmond C, Laakso M, Uusitupa M, Lindi V, Kajatie E, Barker DJP. 2012. International journal of pediatrics. 2012: 6 pages

Obesity and obstructive sleep apnea - Clinical significance of weight loss

Tuomilehto H, Seppä J, Uusitupa M. 2012. Sleep medicine reviews. online: -

Participation, socioeconomic status and group of individual counselling intervention in individuals at high risk for type 2 diabetes: One-year follow-up study of the FIN-D2D-project

Rautio N, Jokelainen J, Oksa H, Saaristo T, Peltonen M, Niskanen L, Saltevo J, Korpi-Hyövälti E, Uusitupa M, Tuomilehto J, Keinänen-Kiukaanniemi S. 2012. Primary care diabetes. 6: 277-283

Ravinto, geenien toiminta, genomiikka ja epigenetiikka

Mutanen M, Uusitupa M. Teoksessa: Aro A, Mutanen M, Uusitupa M(toim.) , 2012. Ravitsemustiede. s. 168-182. Duodecim

Ravintolisien lääkinnällinen käyttö

Uusitupa M, Schwab U. 2012. Erikoislääkäri. 22: 14-18

Ravintolisien lääkinnällinen käyttö

Uusitupa M, Schwab U. 2012. NIVELTIETO. 4: 18-21

Ravitsemus ja diabetes

Uusitupa M. Teoksessa: Aro A, Mutanen M, Uusitupa M(toim.) , 2012. Ravitsemustiede. s. 368-396.

Ravitsemus, kihti ja reumataudit

Uusitupa M. Teoksessa: Aro M, Mutanen M, Uusitupa M(toim.) , 2012. Ravitsemustiede. s. 477-480.

Ravitsemustiede

Aro A, Mutanen M, Uusitupa M. 2012. . . Duodecim

Ravitsemustilan arviointi

Uusitupa M, Fogelholm M. Teoksessa: Aro A, Mutanen M, Uusitupa M(toim.) , 2012. Ravitsemustiede. s. 204-209. Duodecim

Ruokavalio diabeteksen ehkäisyssä ja hoidossa

Uusitupa Matti. 2012. MEDIUUTISET. : 8-9

Sydämen vajaatoiminnan ravitsemushoito

Uusitupa M. Teoksessa: Aro A, Mutanen M, Uusitupa M(toim.) , 2012. Ravitsemustiede. s. 475-476.

Ylipainon ja lihavuuden esiintyvyys tyypin 2 diabetespotilailla

Pajunen P, Keinänen-Kiukaanniemi S, Korpi-Hyövälti E, Männistö S, Niskanen L, Oksa H, Saaristo T, Saltevo J, Sundvall J, Vanhala M, Uusitupa M, Eriksson J, Peltonen M. 2012. Lääkärilehti. 67: 2621-2626

A diet high in fatty fish, bilberries and wholegrain products improves markers of endothelial function and inflammation in individuals with impaired glucose metabolism in a randomised controlled trial: The Sysdimet study

de Mello Vanessa D, Schwab Ursula, Kolehmainen Marjukka, Koenig W, Siloaho Maritta, Poutanen Kaisa, Mykkänen Hannu, Uusitupa Matti. 2011. Diabetologia. 54: 2755-2767

Ageing and associations of fasting plasma glucose and 2 h plasma glucose with HbA1g in apparently healthy population. " FIN-D2D" study

Saltevo JT, Kautiainen H, Niskanen L, Oksa H, Puolijoki H, Sundvall J, Keinänen-Kiukaanniemi S, Peltonen T, Tuomilehto J, Uusitupa M, Mäntyselkä P, Vanhala MJ. 2011. Diabetes research and clinical practice. 93: 344-349

Are we really active in the prevention of obesity and type 2 diabetes at the community level?

Uusitupa M, Tuomilehto J, Puska P. 2011. Nutrition metabolism and cardiovascular diseases. 21: 380-389

Association of ADIPOQ gene variants with body weight, type 2 diabetes and serum adiponectin concentrations: the Finnish Diabetes Prevention Study

Siitonen N, Pulkkinen L, Lindström J, Kolehmainen M, Eriksson JG, Venojärvi M, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Tuomilehto J & Uusitupa M. 2011. Bmc medical genetics. 12: 5

Association of ADIPOR2 gene variants with cardiovascular disease and type 2 diabetes risk in individuals with impaired glucose tolerance: the Finnish Diabetes Prevention Study

Siitonen N, Pulkkinen L, Lindstrom J, Kolehmainen M, Schwab U, Eriksson JG, Ilanne-Parikka P, Keinanen-Kiukaanniemi S, Tuomilehto J, Uusitupa M. 2011. Cardiovascular diabetology. 10: 83

Cardiovascular autonomic dysfunction is associated with central obesity in persons with impaired glucose tolerance

Laitinen T, Lindström J, Eriksson J, Ilanne-Parikka P, Aunola S, Keinänen-Kiukaanniemi S, Tuomilehto J, Uusitupa M. 2011. Diabetic medicine. 28: 699-704

Destiny in your own hands - Does a positive family history matter in the prevention of type 2 diabetes?

Uusitupa Matti, Tuomilehto Jaakko. 2011. Primary care diabetes. 5: 213-214

Family history of diabetes and effectiveness of lifestyle counselling on the cardiometabolic risk profile in individuals at high risk of type 2 diabetes: 1-year follow-up of the FIN-D2D project

Rautio N, Jokelainen J, Oksa H, Saaristo T, Peltonen M, Puolijoki H, Tuomilehto J,Vanhala M, Moilanen L, Uusitupa M, Keinänen-Kiukaanniemi S. 2011. . .

HbA(1c) in diagnosing and predicting Type 2 diabetes in impaired glucose tolerance: the Finnish Diabetes Prevention Study

Pajunen P, Peltonen M, Eriksson JG, Ilanne-Parikka P, Aunola S, Keinänen-Kiukaanniemi S, Uusitupa M, Tuomilehto J & Lindström J: Finnish Diabetes Prevention Study. 2011. Diabetic medicine. 28: 36-42

Impact of positive family history and genetic risk variants on the incidence of diabetes - the Finnish Diabetes Prevention Study

Uusitupa MI, Stancáková A, Peltonen M, Eriksson JG, Lindström J, Aunola S, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Tuomilehto J, Laakso M. 2011. Diabetes care. Online: 1-6

Increase in physical activity and cardiometabolic risk profile change during lifestyle intervention in primary healthcare: 1-year follow-up study among individuals at high risk for type 2 diabetes

Kujala UM, Jokelainen J, Oksa H, Saaristo T, Rautio N, Moilanen L, Korpi-Hyövälti E, Saltevo J, Vanhala M, Niskanen L, Peltonen M, Tuomilehto J, Uusitupa M, Keinänen-Kiukaannemi S. 2011. BMJ open. 1: e000292

Long-term effect of betaine on risk factors associated with the metabolic syndrome in healthy subjects

Schwab U, Alfthan G, Aro A &Uusitupa M. 2011. European journal of clinical nutrition. 65: 70-76

Metabolically healthy and unhealthy obesity phenotypes in the general population: the FIN-D2D Survey

Pajunen P, Kotronen A, Korpi-Hyovalti E, Keinanen-Kiukaanniemi S, Oksa H, Niskanen L, Saaristo T, Saltevo JT, Sundvall J, Vanhala M, Uusitupa M, Peltonen M.. 2011. Bmc public health. 11: 754

Microfibrillar-associated protein 5 is linked with markers of obesity-related extracellular matrix remodeling and inflammation

Vaittinen M, Kolehmainen M, Schwab U, Uusitupa M, Pulkkinen L. 2011. Nutrition and diabetes. 1: e15, 1-6

Miksi kaikki eivät liho?

Uusitupa Matti, Lappalainen Tiina. 2011. Lääkärilehti. 66: 1811-1812a

Millainen on sydämelle terveellinen ruokavalio?

Uusitupa Matti, Schwab Ursula. 2011. Duodecim. 127: 521-4

Mitä lihavuuden lääkehoidossa on luvassa?

Uusitupa Matti, Savolainen Markku. 2011. Lääkärilehti. 66: 2864-2866

Näkökulma. Karppaus - enemmän kuin muotivillitys?

Uusitupa Matti. 2011. Erikoislääkäri. : 144-145

Physical activity attenuates the influence of FTO variants on obesity risk: A meta-analysis of 218,166 adults and 19,268 children

Kilpeläinen Tuomas O, Qi Lu, Brage Soren, Sharp Stephen J., Sonestedt Emily, Demerath Ellen, Ahmad Tariq, Mora Samia, Kaakinen Marika, Sandholt Camilla H, Holzapfel Christina, Autenrieth Christine S., Hyppönen Elina, Cauchi Stéphane , He Meian, Kutalik Zoltan, Kumari Meena, Stancaková Alena, Meidtner Karina, Balkau Beverley et al.. 2011. PLoS medicine. 8: e1001116

Population-level effects of the national diabetes prevention programme (FIN-D2D) on the body weight, the waist circumference, and the prevalence of obesity.

Salopuro TM, Saaristo T, Oksa H, Puolijoki H, Vanhala M, Ebeling T, Niskanen L, Tuomilehto J, Uusitupa M, Peltonen M.. 2011. Bmc public health. 11: 350

Ravitsemussuosituksien nykylinjat YK:n agendalla

Uusitupa Matti. 2011. SYDÄN: SUOMEN SYDÄNTAUTILIITON JULKAISU. 54: 7

Response to Hoenselaar from Pedersen et al

Pedersen JI, Norum KR, James PT, Brouwer IA, Katan MB, Clarke R, Elmadfa I, Kris-Etherton PM, Kromhout D, Margetts BM, Mensink RP, Rayner M, Uusitupa M. 2011. British journal of nutrition. online: 452-454

Response to Ravnskov et al. on saturated fat and CHD

Pedersen JI, Norum KR, James PT, Brouwer IA, Katan MB, Clarke R, Elmadfa I, Kris-Etherton PM, Kromhout D, Margetts BM, Mensink RP, Rayner M, Uusitupa M.. 2011. British journal of nutrition. online: 458-460

Response to Slow et al.

Schwab U, Alfthan G, Aro A, Uusitupa M. 2011. European journal of clinical nutrition. 65: 772

Socioeconomic position and effectiveness of lifestyle intervention in prevention of type 2 diabetes: One-year follow-up of the FIN-D2D project

Rautio N, Jokelainen J, Oksa H, Saaristo T, Peltonen M, Niskanen L, Puolojoki H, Vanhala M, Uusitupa M, Keinänen-Kiukaanniemi S. & on the belalf of FIN-D2D study group. 2011. Scandinavian journal of public health. 39: 561-70

Solakaksi syömällä vai rajoittamalla hiilihydraatteja

Uusitupa Matti, Raussi Emmikaisa. 2011. Kehittyvä Elintarvike. 5: 12-15

Tenomodulin variants, APOE and Alzheimer's disease in a Finnish case-control cohort. Negative results

Tolppanen AM, Helisalmi S, Hiltunen M, Kolehmainen M, Schwab U, Pirttilä T, Pulkkinen L, Uusitupa M & Soininen H.. 2011. Neurobiology of aging. 32: 546.e7-546.e9

Tepsiikö vähähiilihydraattinen ruokavalio lihavuuden hoidossa?

Raussi Emmikaisa, Uusitupa Matti. 2011. Lääkärilehti. 66: 2659-2664a

The importance of reducing SFA to limit CHD

Pedersen JI, James PT, Brouwer IA, Clarke R, Elmadfa I, Katan MB, Kris-Etherton PM, Kromhout D, Margetts BM, Mensink RP, Norum KR, Rayner M, Uusitupa M. 2011. British journal of nutrition. 106: 961-963

Whole grain products, fish and bilberries alter glucose and lipid metabolism in a randomized, controlled trial: the sysdimet study

Lankinen Maria, Schwab Ursula, Kolehmainen Marjukka, Paananen Jussi, Poutanen Kaisa, Mykkänen Hannu, Seppänen-Laakso Tuulikki, Gylling Helena, Uusitupa Matti, Ore¿ič Matej. 2011. PLoS ONE. 6: e22646

A psyllium fiber-enriched meal strongly attenuates postprandial gastrointestinal peptide release in healthy young adults

Karhunen LJ, Juvonen KR, Flander SM, Liukkonen K-H, Lähteenmäki L, Siloaho M, Laaksonen DE, Hetzig K-H, Uusitupa MI & Poutanen KS. 2010. Journal of nutrition. 140: 737-744

Association of the FTO gene variant (rs9939609) with cardiovascular disease in men with abnormal glucose metabolism - The Finnish Diabetes Prevention Study

Lappalainen T, Kolehmainen M, Schwab US, Tolppanen AM, Stančáková A, Lindström J, Eriksson JG, Keinänen-Kiukaanniemi S, Aunola S, Ilanne-Parikka P, Herder C, Koenig W, Gylling H, Kolb H &Tuomilehto J for the Finnish diabetes prevention study group. 2010. Nutrition metabolism and cardiovascular diseases. 2011/21: 691-698/2011

Best of sleep medicine 2010. Lifestyle intervention with weight reduction: first-line treatment in mild obstructive sleep apnea.

Ed. Lee-Chiong T. Contributors: Tuomilehto HPI, Seppä JM, Partinen MM, Peltonen M, Gylling H, Tuomilehto JO, Vanninen EJ, Kokkarinen J, Sahlman JK, et.al.. 2010. . . Teofilio Lee-Chiong

Brain electrical activity during food presentation in obese binge-eating women

Tammela LI , Pääkkönen A, Karhunen LJ, Karhu J, Uusitupa MIJ & Kuikka JT. 2010. Clinical physiology and functional imaging. 30: 135-140

Cardiometabolic profile of people screened for high risk of type 2 diabetes in a national diabetes prevention programme (FIN-D2D)

Saaristo T, Moilanen L, Jokelainen J, Korpi-Hyövälti E, Vanhala M, Saltevo J, Niskanen L, Peltonen M, Oksa H, Cederberg H, Tuomilehto J, Uusitupa M, Keinänen-Kiukaanniemi S. 2010. Primary care diabetes. 4: 231-239

Cholesterol absorption decreases after Roux-en-Y gastric bypass but not after gastric banding

Pihlajamäki J, Grönlund S, Simonen M, Käkelä P, Moilanen L, Pääkkönen M, Pirinen E, Kolehmainen M, Kärjä V, Kainulainen S, Uusitupa M, Alhava E, Miettinen TA, Gylling H. 2010. Metabolism: clinical and experimental. 59: 866-872

Diabetesriskia voidaan vähentää perusterveydenhuollon keinoin. Taudin ilmaantuvuus pieneni D2D-hankkeessa

Saaristo T, Moilanen L, Jokelainen J, Oksa H, Korpi-Hyövälti E, Saltevo J, Vanhala M, Niskanen L, Peltonen M, Tuomilehto J, Uusitupa M & Keinänen-Kiukaanniemi S. 2010. Lääkärilehti. 65: 2369-2379

Diabetesriskiä voidaan vähentää perusterveydenhuollon keinoin. Taudin ilmaantuvuus pieneni D2D-hankkeessa.

Saaristo T, Moilanen L, Jokelainen J, Oksa H, Korpi-Hyövälti E, Saltevo J, Vanhala M, Niskanen L, Peltonen M, Tuomilehto J, Uusitupa M, Keinänen-Kiukaanniemi S. 2010. Lääkärilehti. 65: 2369-2379

Effect of weight loss on inflammation in patients with mild obstructive sleep apnea.

Sahlman J, Seppä J, Herder C, Peltonen M, Peuhkurinen K, Gylling H, Vanninen E, Tukiainen H, Punnonen K, Partinen M, Uusitupa M, Tuomilehto H.. 2010. Nutrition metabolism and cardiovascular diseases. online: 1-8

Gene Expression of FTO in Human Subcutaneous Adipose Tissue, Peripheral Blood Mononuclear Cells and Adipocyte Cell Line.

Lappalainen T, Kolehmainen M, Schwab U, Pulkkinen L, de Mello VD, Vaittinen M, Laaksonen DE, Poutanen K, Uusitupa M, Gylling H. 2010. Journal of nutrigenetics and nutrigenomics. 3: 37-45

Ghrelin in diabetes and metabolic syndrome

Pulkkinen L, Ukkola O, Kolehmainen M, Uusitupa M. 2010. International journal of peptides. 2010: ID 248948, 11 PAGES

Leisure-time physical activity and the metabolic syndrome in the Finnish diabetes prevention study

Ilanne-Parikka P, Laaksonen DE, Eriksson JG, Lakka TA, Lindström J, Peltonen M, Aunola S, Keinänen-Kiukaanniemi S, Uusitupa M & Tuomilehto J. On behalf of the Finnish diabetes prevention study group. 2010. Diabetes care. 33: 1610-1617

Lifestyle intervention for prevention of type 2 diabetes in primary health care

Saaristo T, Moilanen L, Korpi-Hyövälti E, Vanhala M, Saltevo J, Niskanen L, Jokelainen J, Peltonen M, Oksa H, Tuomilehto J, Uusitupa M, Keinänen-Kiukaanniemi S.. 2010. Diabetes care. 33: 2146-2151

Lihavuuden ja glukoosiaineenvaihdunnan häiriöiden esiintyvyydessä on selviä alueellisia eroja Suomessa

Salopuro T, Saaristo T, Korpi-Hyövälti E, Oksa H, Keinänen-Kiukaanniemi S, Saltevo J, Vanhala M, Niskanen L, Moltchanova E, Sundvall J, Tuomilehto J, Uusitupa M, Peltonen M. 2010. Lääkärilehti. 65: 2381-2388

Mid-infrared spectroscopy and multivariate curve resolution

Lundbom J, Kolehmainen M Pulkkinen L, Soininen P , Tiainen M, Schwab U, Uusitupa M & Tammi M. 2010. European journal of lipid science and technology. 112: 1308-1314

Prevention strategies for type 2 diabetes should be based on evidence-based medical nutrition data.

Uusitupa M, Lindström J, Tuomilehto J. 2010. Diabetologia. 53: 1809-1810

Quality of diet is important for the prevention of cardiovascular disease.

Uusitupa Matti. 2010. Journal of internal medicine. 269: 148-9

Semisolid meal enriched in oat bran decreases plasma glucose and insulin levels, but does not change gastrointestinal peptide responses or short-term appetite in healthy subjects

Juvonen K, Salmenkallio-Marttila M, Lyly M, Liukkonen KH, Lähteenmäki L, Laaksonen D, Uusitupa M, Herzig K, Poutanen K & Karhunen L. 2010. Nutrition metabolism and cardiovascular diseases. 21/2011: 2011/748-756

Socio-economic differences in dysglycemia and lifestyle-related risk factors in the Finnish middle-aged population.

Wikström K, Lindström J, Tuomilehto J, Saaristo TE, Korpi-Hyövälti E, Oksa H, Vanhala M, Niskanen L, Keinänen-Kiukaanniemi S, Uusitupa M, Peltonen M. 2010. European journal of public health. online: 1-7

Sustained improvement in mild obstructive sleep apnea after a diet- and physical activity-based lifestyle intervention: postinterventional follow-up.

Tuomilehto H, Gylling H, Peltonen M, Martikainen T, Sahlman J, Kokkarinen J, Randell J, Tukiainen H, Vanninen E, Partinen M, Tuomilehto J, Uusitupa M, Seppä J; for the Kuopio Sleep Apnea Group.. 2010. American journal of clinical nutrition. 92: 688-696

Tenomodulin gene and obesity-related phenolypes

Tolppanen A-M, Kolehmainen M, Pulkkinen L & Uusitupa M. 2010. Annals of medicine. 42: 265-275

The activation of the inflammatory cytokines in overweight patients with mild obstructive sleep apnoea.

Sahlman J, Miettinen K, Peuhkurinen K, Seppä J, Peltonen M, Herder C, Punnonen K, Vanninen E, Gylling H, Partinen M, Uusitupa M, Tuomilehto H; Kuopio Sleep Apnoea Group. 2010. Journal of sleep research. 19: 341-348

The rs1800629 polymorphism in the TNF gene interacts with physical activity on the changes in C-reactive protein levels in the Finnish diabetes prevention study

Kilpeläinen TO, Laaksonen DE, Lakka TA, Herder C, Koenig W, Lindström J, Eriksson JG, Uusitupa M, Kolb H, Laakso M, Tuomilehto J, for the Finnish Diabetes Prevention Study Group. 2010. Experimental and clinical endocrinology and diabetes. 118: 757-759

Tyypin 2 diabetes - vakava paikka

Tuomilehto J, Uusitupa M. 2010. Lääkärilehti. 65: 2345

Anti-inflammatory effect of lifestyle changes in the Finnish diabetes prevention study

Herder C, Peltonen M, Koenig W, Sütfels K, Lindström J, Martin S, Ilanne-Parikka P, Eriksson JG, Aunola S, Keinänen-Kiukaanniemi S, Valle TT, Uusitupa M, Kolb H, Tuomilehto J, for the Finnish Diabetes Prevention Study Group. 2009. Diabetologia. 52: 433-442

Association of sequence variations in the gene encoding insulin-like growth factor binding protein 5 with adiponectin

Kallio P, Tolppanen A-M, Kolehmainen M, Poutanen K, Lindström J, Tuomilehto J, Kuulasmaa T, Kuusisto J, Pulkkinen L, Uusitupa M, Kallio P, Tolppanen A-M, Kolehmainen M, Poutanen K, Pulkkinen L, Uusitupa M. 2009. International journal of obesity. 33: 80-88

Educational attainment and effectiveness of lifestyle intervention in the Finnish diabetes prevention study

Wikström K, Peltonen M, Eriksson JG, Aunola S, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Uusitupa M, Tuomilehto J, Lindström J. 2009. Diabetes research and clinical practice. 86: e1-e5

Fatty fish intake decreases lipids related to inflammation and insulin signaling-A lipidomics approach

Lankinen M, Schwab U, Erkkilä A, Seppänen-Laakso T, Hannila M-L, Mussalo H, Lehto S, Uusitupa M, Gylling H, Oresic M. 2009. PLoS ONE. 4: [1-9]

From the Authors: Avoiding the supine posture during sleep for patients with mild obstructive sleep apnea

Tuomilehto H, Seppä J, Partinen M, Uusitupa M. 2009. American journal of respiratory and critical care medicine

From the authors: Long-term weight loss and maintenance in morbidly obese individuals wih obstructive sleep apnea

Tuomilehto H, Seppä J, Gylling H, Uusitupa M. 2009. American journal of respiratory and critical care medicine

Lifestyle intervention with weight reduction. First line treatment in mild obstructive sleep apnea

Tuomilehto HPI, Seppä JM, Partinen MM, Peltonen M, Gylling H, Tuomilehto JOI, Vanninen EJ, Kokkarinen J, Sahlman JK, Martikainen T, Soini EJO, Randell J, Tukiainen H, Uusitupa M, on behalf of the Kuopio Sleep Apnea Group. 2009. American journal of respiratory and critical care medicine. 179: 320-327

Link between plasma ceramides, inflammation and insulin resistance: association with serum IL-6 concentration in patients with coronary heart disease

De Mello VDF, Lankinen M, Schwab U, Kolehmainen M, Lehto S, Seppä-Laakso T, Oresic M, Pulkkinen L, Uusitupa M, Erkkilä AT, De Mello VDF, Lankinen M, Schwab U, Kolehmainen M, Pulkkinen L, Uusitupa M. 2009. Diabetologia. 52: 2612-2615

Obstruktiivinen uniapnea ja lihavuus

Tuomilehto H, Seppä J, Gylling H, Uusitupa M. 2009. Duodecim

Single nucleotide polymorphisms of the tenomodulin gene (TNMD) in age-related macular degeneration

Tolppanen A-M, Nevalainen T, Kolehmainen M, Seitsonen S, Immonen I, Uusitupa M, Kaarniranta K, Pulkkinen L, Tolppanen A-M, Kolehmainen M, Uusitupa M, Pulkkinen L. 2009. Molecular vision. 15: 762-770

Sleep duration, lifestyle intervention, and incidence of type 2 diabetes in impaired glucose tolerance. The Finnish diabetes prevention study

Tuomilehto H, Peltonen M, Partinen M, Lavigne G, Eriksson JG, Herder C, Aunola S, Keinänen-Kiukaanniemi S, Ilanne-Parikka P, Uusitupa M, Tuomilehto J, Lindström J, on behalf of the Finnish diabetes prevention study group. 2009. Diabetes care. 32: 1965-1971

Ten-year morality and cardiovaskular morabidity in the Finnish diabetes prevention study - secondary analysis of the randomized trial

Uusitupa M, Peltonen M, Lindström J, Aunola S, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Valle TT, Eriksson JG, Tuomilehto J, for the Finnish Diabetes Prevention Study Group. 2009. PLoS ONE. 4: e5656

The effect of fatty or lean fish intake on inflammatory gene expression in peripheral blood mononuclear cells of patients with coronary heart disease

De Mello VDF, Erkkilä AT, Schwab US, Pulkkinen L, Kolehmainen M, Atalay M, Mussalo H, Lankinen M, Oresic M, Lehto S, Uusitupa M, De Mello VDF, Schwab US, Pulkkinen L, Kolehmainen M, Lankinen M, Uusitupa M. 2009. European journal of nutrition. 48: 447-455

The effect of glycaemic control on the quantitative characteristics of retinopathy lesions in patients with type 2 diabetes mellitus: 10-year follow-up study

Kalesnykiene V, Sorri I, Voutilainen R, Uusitupa M, Niskanen L, Uusitalo H, Uusitupa M. 2009. Graefes archive for clinical and experimental ophthalmology. 247: 335-341

Variation in the UCP2 and UCP3 genes associated with abdominal obesity and serum lipids: The Finnish diabetes prevention study

Salopuro T, Pulkkinen L, Lindström J, Kolehmainen M, Tolppanen A-M, Eriksson JG, Valle TT, Aunola S, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Tuomilehto J, Laakso M, Uusitupa M, Salopuro T, Pulkkinen L, Kolehmainen M, Tolppanen A-M, Uusitupa M. 2009. Bmc medical genetics. 10: [13 p.]

Viscosity of oat bran-enriched beverages influences gastrointestinal hormonal responses in healthy humans1-3

Juvonen KR, Purhonen A-K, Salmenkallio-Marttila M, Lähteenmäki L, Laaksonen DE, Herzig K-H, Uusitupa MIJ, Poutanen KS, Karhunen LJ, Juvonen KR, Uusitupa MIJ, Poutanen KS. 2009. Journal of nutrition. 139: 461-466

Determinants for the effectiveness of lifestyle intervention in the Finnish diabetes prevention study

Lindström J, Peltonen M, Eriksson JG, Aunola S, Hämäläinen H, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Uusitupa M, Tuomilehto J, for the Finnish Diabetes Prevention Study (DPS) group. 2008. Diabetes care. 31: 857-862

Downregulation of genes involved in NFkappaB activation in peripheral blood mononuclear cells after weight loss is associated with the improvement of insulin sensitivity in individuals with the metabolic syndrome: the GENOBIN study

De Mello V, Kolehmainen M, Pulkkinen L, Schwab U, Mager U, Laaksonen DE, Niskanen L, Gylling H, Atalay M, Rauramaa R, Uusitupa M, De Mello V, Kolehmainen M, Pulkkinen L, Schwab U, Mager U, Gylling H, Uusitupa M. 2008. Diabetologia. 51: 2060-2067

Effect of lifestyle intervention on the occurrence of metabolic syndrome and its components in the Finnish diabetes prevention study

Ilanne-Parikka P, Eriksson JG, Lindström J , Peltonen M, Aunola S, Hämäläinen H, Keinänen-Kiukaanniemi S, Laakso M, Valle TT, Lahtela J, Uusitupa M, Tuomilehto J, on behalf of the Finnish Diabetes Prevention Study Group. 2008. Diabetes care. 31: 805-807

Effect of weight loss on cytokine messenger RNA expression in peripheral blood mononuclear cells of obese subjects with the metabolic syndrome

de Mello VDF, Kolehmainen M, Schwab U, Mager U, Laaksonen DE, Pulkkinen L, Niskanen L, Gylling H, Atalay M, Rauramaa R, Uusitupa M, Ferreira de Mello V, Kolehmainen M, Schwab U, Mager U, Pulkkinen L, Gylling H, Uusitupa M. 2008. Metabolism: clinical and experimental. 57: 192-199

Effects of fatty and lean fish intake on blood pressure in subjects with coronary heart disease using multiple medications

Erkkilä AT, Schwab US, De Mello VDF, Lappalainen T, Mussalo H, Lehto S, Kemi V, Lamberg-Allardt C, Uusitupa MIJ. 2008. European journal of nutrition. 47: 319-328

Expression of ghrelin gene in peripheral blood mononuclear cells and plasma ghrelin concentrations in patients with metabolic syndrome

Mager U, Kolehmainen M, de Mello VDF, Schwab U, Laaksonen DE, Rauramaa R, Gylling G, Atalay M, Pulkkinen L, Uusitupa M, Mager U, Kolehmainen M, Ferreira, Schwab U, Gylling H, Pulkkinen L, Uusitupa M. 2008. European journal of endocrinology. 158: 499-510

Genetics or lifestyle - How do we prevent diabetes?

Uusitupa M. Teoksessa: (toim.) , 2008. European Endocrinolgy. [Online]. s. 19-21. Touch Briefings

Heterogeneity of breast cancer associations with five susceptibility loci by clinical and pathological characteristics

Garcia-Closas M, Hall P, Nevanlinna H ..., Mannermaa A, Uusitupa M, Eskelinen M, Tengström M, Kosma V-M, Kataja V, Chenevix-Trench G .... 2008. PLoS genetics. 4: [e1000054]

Inflammation markers are modulated by responses to diets differing in postprandial insulin responses in individulas with the metabolic syndrome1-3

Kallio P, Kolehmainen M, Laaksonen DE, Pulkkinen L, Atalay M, Mykkänen H, Uusitupa M, Poutanen K, Niskanen L, Kallio P, Kolehmainen M, Pulkkinen L, Mykkänen H, Uusitupa M, Poutanen K. 2008. American journal of clinical nutrition. 87: 1497-503

Interaction of single nucleotide polymorphisms in ADRB2, ADRB3, TNF, IL6, IGF1R, LIPC, LEPR, and GHRL with physical activity on the risk of type 2 diabetes mellitus and changes in characteristics of the metabolic syndrome. The Finnish Diabetes Prevention Study

Kilpeläinen TO, Lakka TA, Laakosnen DE, Mager U, Salopuro T, Kubaszek A, Todorova B, Laukkanen O, Lindström J, Eriksson JG, Hämäläinen H, Aunola S, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Tuomilehto J, Laakso M, Uusitupa M. 2008. Metabolism: clinical and experimental. 57: 428-436

Lifestyle intervention, diabetes, and cardiovascular disease

Lindström J, Uusitupa M. 2008. The Lancet

Long-term repeatability of measures of early insulin secretion derived from an intravenous glucose tolerance test and conversion from impaired glucose tolerance to diabetes

Laaksonen DE, Niskanen L, Mykkänen H, Juntunen KS, Schwab U, Kolehmainen M, Rauramaa R, Tuomilehto J, Uusitupa M, Kolehmainen M, Uusitupa M. 2008. Annals of medicine. 40: 303-311

NAD(P)H:quinone oxidoreductase 1 NQ01*2 genotype (P187S) is a strong prognostic and predictive factor in breast cancer

Fagerholm Rainer, Hofstetter Barbara, Tommiska Johanna, Aaltonen Kirsimari, Vrtel Radek, Syrjäkoski Kirsi, Kallioniemi Anne, Kilpivaara Outi, Mannermaa Arto, Kosma Veli-Matti, Uusitupa Matti, Eskelinen Matti, Kataja Vesa, Aittomäki Kristiina. 2008. Nature genetics. 40: 844-853

SNPs in PPARG associte with type 2 diabetes and intract with physival activity

Kilpeläinen TO, Lakka TA, Laaksonen DE, Lindström J, Eriksson JG, Valle TT, Hämäläinen H, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Lindi V, Tuomilehto J, Uusitupa M, Laakso M. 2008. Medicine and science in sports and exercise. 40: 25-33

Serum concentrations and expressions of serum amyloid A and leptin in adipose tissue are interrelated: the Genobin Study

Lappalainen T, Kolehmainen M, Schwab U, Pulkkinen L, Laaksonen DE, Rauramaa R, Uusitupa M, Gylling H. 2008. European journal of endocrinology. 158: 333-341

The G-250A polymorphism in the hepatic lipase gene promotor is associated with changes in hepatic lipase activity and LDL cholesterol:The KANWU study

Lindi V, Schwab U, Louheranta A, Vessby B, Hermansen K, Tapsell L, Riccardi G, Rivellese AA, Laakso M, Uusitupa MIJ, KANWU Study Group. 2008. Nutrition metabolism and cardiovascular diseases. 18: 88-95

The genetic variation in the tenomodulin gene is associated with serum total and LDL cholesterol in a body size-dependent manner

Tolppanen A-M, Pulkkinen L, Kuulasmaa T, Kolehmainen M, Schwab U, Lindström J, Tuomilehto J, Uusitupa M, Kuusisto J. 2008. International journal of obesity. 32: 1868-1872

The genetic variation of the tenomodulin gene (TNMD) is associated with serum levels of systemic immune mediators--the Finnish Diabetes Prevention Study

Tolppanen AM, Pulkkinen L, Herder C, Koenig W, Kolehmainen M, Lindström J, Tuomilehto J, Uusitupa M. 2008. Genetics in medicine. 10: 536-544

Triacylglycerol fatty acid composition in diet-induced weight loss in subjects with abnormal glucose metabolism - the GENOBIN study

Schwab U, Seppänen-Laakso T, Yetukuri L, Ågren J, Kolehmainen M, Laaksonen DE, Ruskeepää A-L, Gylling H, Uusitupa M, Oresic M, for the Genobin Study Group, Schwab U, Kolehmainen M, Gylling H, Uusitupa M. 2008. PLoS ONE. 3: e2630

Variations in the ghrelin receptor gene associate with obesity and glucose metabolism in individuals with impaired glucose tolerance

Mager U, Degenhardt T, Pulkkinen L, Kolehmainen M, Tolppanen A-M, Lindström J, Eriksson JG, Carlberg, Tuomilehto J, Uusitupa M, for the Finnish Diabetes Prevention Study Group. 2008. PLoS ONE. 3: e2941

Weight reduction modulates expression of genes involved in extracellular matrix and cell death: the GENOBIN study

Kolehmainen M, Salopuro T, Schwab US, Kekäläinen J, Kallio P, Laaksonen DE, Pulkkinen L, Lindi VI, Sivenius K, Mager U, Siitonen N, Niskanen L, Gylling H, Rauramaa R, Uusitupa M, Kolehmainen M, Salopuro T, Schwab US, Kallio P, Pulkkinen L, Lindi VI. 2008. International journal of obesity. 32: 292-303

CYP1A1 and CYP1B1 genetic polymorphisms, smoking and breast cancer risk in a Finnish caucasian population

Sillanpää P, Heikinheimo L, Kataja V, Eskelinen M, Kosma V-M, Uusitupa M, Vainio H, Metsola K, Hirvonen A. 2007. Breast cancer research and treatment. 104: 287-297

Costs of a self-selected, health-promoting diet among the participants of the Finnish Diabetes Prevention Study

Ottelin A-M, Lindström J, Peltonen M, Martikainen J, Uusitupa M, Gylling H, Poutanen K, Louheranta A, Mannelin M, Paturi M, Salminen V, Tuomilehto J, Ottelin A-M, Uusitupa M, Gylling H, Poutanen K. 2007. Diabetes care. 30: 1275-1277

Dietary carbohydrate modification induces alterations in gene expression in abdominal subcutaneous adipose tissue in persons weith the metabolic syndrome: the FUNGENUT study1-4

Kallio P, Kolehmainen M, Laaksonen DE, Kekäläinen J, Salopuro T, Sivenius K, Pulkkinen L, Mykkänen HM, Niskanen L, Uusitupa M, Poutanen KS, Kallio P, Kolehmainen M, Poutanen KS. 2007. American journal of clinical nutrition. 85: 1417-1427

Fish oil, insulin sensitivity, insulin secretion and glucose toleranse in healthy people: Is there any effect of fish oil supplementation in relation to the type of backround diet and habitual dietary intake of n-6 and n-3 fatty acids?

Giacco R, Cuomo V, Vessby B, Uusitupa M, Hermansen K, Meyer BJ, Riccardi G, Rivellese AA, KANWU study group. 2007. Nutrition metabolism and cardiovascular diseases. 17: 572-580

Hiilihydraattien laatu säätelee geenien ilmentymistä rasvakudoksessa

Kallio P, Kolehmainen M, Laaksonen DE, Kekäläinen J, Salopuro T, Sivenius K, Pulkkinen L, Mykkänen HM, Niskanen L, Uusitupa M, Poutanen KS, Kallio P, Kolehmainen M, Salopuro T, Pulkkinen L, Mykkänen HM, Uusitupa M, Poutanen KS. 2007. Duodecim. 123: 1143-1144

Increased physical activity is a cornerstone in the prevention of type 2 diabetes in high-risk individuals

Laaksonen DE, Lindström J, Tuomilehto J, Uusitupa M. 2007. Diabetologia

Kansantaudit, ravitsemus ja perimä

Uusitupa M. 2007. BOLUS : RAVITSEMUSTERAPEUTTIEN YHDISTYKSEN LEHTI. : 12-14

Lifestyle intervention to prevent diabetes in men and women with impaired glucose tolerance is cost-effective

Lindgren P, Lindström J, Tuomilehto J, Uusitupa M, Peltonen M, Jönsson B, De Faire U, Hellénius M-L, The DPS Study Group. 2007. International journal of technology assessment in health care. 23: 177-183

Moderate increase in dietary sucrose does not influence fasting or postprandial serum lipids regardless of the presence of apolipoprotein E2 allele in healthy subjects

Erkkilä AT, Schwab US, Ågren JJ, Hallikainen M, Gylling H, Uusitupa MIJ, Schwab US, Uusitupa MIJ. 2007. European journal of clinical nutrition. 61: 1094-1101

No observed local immunological response at cell level after five years of oats in adult coeliac disease

Kemppainen T, Janatuinen E, Holm K, Kosma V-M, Heikkinen M, Mäki M, Laurila K, Uusitupa M, Julkunen R. 2007. Scandinavian journal of gastroenterology. 42: 54-59

Physical activity modifies the effect of SNPs in the SLC2A2 (GLUT2) and ABCC8 (SUR1) genes on the risk of developing type 2 diabetes

Kilpeläinen TO, Lakka TA, Laaksonen DE, Laukkanen O, Lindström J, Eriksson JG, Valle TT, Hämäläinen H, Aunola S, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Tuomilehto J, Uusitupa M, Laakso M, for the Finnish Diabetes Prevention Study Group, Laakso M. 2007. Physiological genomics. 31: 264-272

Physical activity, diet, and incident diabetes in relation to an ADRA2B polymorphism

Laaksonen D, Siitonen N, Lindström J, Eriksson JG, Reunanen P, Tuomilehto J, Uusitupa M, for Finnish Diabetes Prevention Study Group. 2007. Medicine and science in sports and exercise. 39: 227-232

Serum adipokines are associated with cholesterol metabolism in the metabolic syndrome

Hallikainen M, Kolehmainen M, Schwab U, Laaksonen DE, Niskanen L, Rauramaa R, Pihlajamäki J, Uusitupa M, Miettinen TA, Gylling H, Kolehmainen M. 2007. Clinica chimica acta. 383: 126-132

Tenomodulin is associated with obesity and diabetes risk: the Finnish diabetes prevention study

Tolppanen AM, Pulkkinen L, Kolehmainen M, Schwab U, Lindström J, Tuomilehto J, Uusitupa M. 2007. Obesity. 15: 1082

Tyypin 2 diabeteksen ehkäisy

Laakso M, Uusitupa M. 2007. Duodecim. 123: 1439-1447

Variants of transcription factor 7-like 2 (TCF7L2) gene predict conversion to type 2 diabetes in the Finnish Diabetes Prevention Study and are associated with impaired glucose regulation and impaired insulin secretion

Wang J, Kuusisto J, Vänttinen M, Kuulasmaa T, Lindström J, Tuomilehto J, Uusitupa M, Laakso M, Laakso M. 2007. Diabetologia. 50: 1192-1200

Association between ghrelin gene variations and blood pressure in subjects with impaired glucose tolerance

Mager U, Kolehmainen M, Lindström J, Eriksson JG, Valle TT, Hämäläinen H, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Tuomilehto JO, Pulkkinen L, Uusitupa MI, for the Finnish diabetes prevention study group, Mager U, Kolehmainen M, Pulkkinen L. 2006. American journal of hypertension. 19: 920-926

Association of sequence variations in the gene encoding adoponectin receptor 1 (ADIPOR1) with body size and insulin levels. The Finnish diabetes prevention study

Siitonen N, Pulkkinen L, Mager U, Lindström J, Eriksson JG, Valle TT, Hämäläinen H, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Tuomilehto J, Laakso M, Uusitupa M, for the Finnish diabetes prevention study group, Siitonen N, Pulkkinen L, Mager U. 2006. Diabetologia. 49: 1795-1805

Association of the Leu72Met polymorphism of the ghrelin gene with the risk of type 2 diabetes in subjects with impaired glucose tolerance in the Finnish diabetes prevention study

Mager U, Lindi V, Lindström J, Eriksson JG, Vallet TT, Hämäläinen H, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Tuomilehto J, Laakso M, Pulkkinen L, Uusitupa M, for the Finnish diabetes prevention study group, Mager U, Lindi V, Pulkkinen L. 2006. Diabetic medicine. 23: 685-689

Dietary (n-3) fatty acids reduce plasma F2-isoprostanes but not prostaglandin F2alfa in healthy humans

Nälsén C, Vessby B, Berglund L, Uusitupa M, Hermansen K, Riccardi G, Rivellese A, Storlien L, Erkkilä A, Ylä-Herttuala S, Tapsell L, Basu S. 2006. Journal of nutrition. 136: 1222-1228

Effects of dietary saturared, monounsaturated, and n-3 fatty acids on blood pressure in healthy subjects 1-3

Rasmussen BM, Vessby B, Uusitupa M, Berglund L, Pedersen E, Riccardi G, Rivellese AA, Tapsell L, Hermandsen K, for the KANWU Study Group. 2006. American journal of clinical nutrition. 83: 221-226

Effects of hempseed and flaxseed oils on the profile of serum lipids, serum total and lipoprotein lipid concentrations and haemostatic factors

Schwab US, Callaway JC, Erkkilä AT, Gynther J, Uusitupa MIJ, Järvinen T. 2006. European journal of nutrition. 45: 470-477

High-fibre, low-fat diet predicts long-term weight loss and decreased type 2 diabetes risk: the Finnish diabetes prevention study

Lindström J, Peltonen M, Eriksson JG, Louheranta A, Fogelholm M, Uusitupa M, Tuomilehto J. 2006. Diabetologia. 49: 912-920

Impact of sugar beet pectin and polydextrose on fasting and postprandial glycemia and fasting concentrations of serum total and lipoprotein lipids in middle-aged subjects with abnormal glucose metabolism

Schwab U, Louheranta A, Törrrönen A, Uusitupa M. 2006. European journal of clinical nutrition. 60: 1073-1080

Ketkä tarvitsevat vitamiinejä?

Uusitupa M. 2006. Lääkärilehti

Lihavan potilaan tutkiminen ja hoitomuodon valinta

Mustajoki P, Rissanen A, Uusitupa M. Teoksessa: Mustajoki P. Fogelholm M, Rissanen A, Uusitupa M(toim.) , 2006. Lihavuus. Ongelma ja hoito. 3. uud. p.. s. 158-166. Duodecim

Lihavuus ja terveys

Uusitupa M. Teoksessa: Mustajoki P. Fogelholm M, Rissanen A, Uusitupa M(toim.) , 2006. Lihavuus. Ongelma ja hoito. 3. uud. p.. s. 25-38. Duodecim

Orally administered betaine has an acute and dose-dependent effect on serum betaine and plasma homocysteine concentrations in healthy humans

Schwab U, Törrönen A, Meririnne E, Saarinen M, Alfthan G, Aro A, Uusitupa M. 2006. Journal of nutrition. 136: 34-38

Perimä ja lihavuus

Uusitupa M. Teoksessa: Mustajoki P. Fogelholm M, Rissanen A, Uusitupa M(toim.) , 2006. Lihavuus. Ongelma ja hoito. 3. uud. p.. s. 86-99. Duodecim

Rasvakudos - aineenvaihdunta ja merkitys lihavuudessa

Kolehmainen M, Uusitupa M. Teoksessa: Mustajoki P. Fogelholm M, Rissanen A, Uusitupa M(toim.) , 2006. Lihavuus. Ongelma ja hoito. 3. uud. p.. s. 62-70. Duodecim

Refinement of the 22q12-q13 Breast Cancer-Associated Region:Evidence of TMPRSS6 as a Candidate in an Eastern Finnish Population

Hartikainen JM, Tuhkanen H, Kataja V, Eskelinen M, Uusitupa M, Kosma V-M, Mannermaa A. 2006. Clinical cancer research. 12: 1454-1462

Serum uric acid as a harbinder of metabolic outcome in subjects with impaired glucose tolerance

Niskanen L, Laaksonen DE, Lindström J, Eriksson JG, Keinänen-Kiukaanniemi S, Ilanne-Parikka P, Aunola S, Hämäläinen H, Tuomilehto J, Uusitupa M, for the Finnish Diabetes Prevention Study Group. 2006. Diabetes care

Sustained reductione in the incidence of type 2 diabetes by lifestyle intervention: follow-up of the Finnish diabetes prevention study

Lindström J, Ilanne-Parikka P, Peltonen M, Aunola S, Erikssom JG, Hämäläinen H, Härkönen P, Keinänen-Kiukaanniemi S, Laakso M, Louheranta A, Mannelin M, Paturi M, Sundvall J, Valle TT, Uusitupa M, Tuomilehto J. 2006. The Lancet. 368: 1673-1679

Systemic immune mediators and lifestyle changes in the prevention of type 2 diabetes. Results from the Finnish diabes prevention study

Herder C, Peltonen M, Koenig W, Kräft I, Mûller-Scholze S, Martin S, Lakka T, Ilanne-Parikka P, Eriksson JG, Hämäläinen H, Keinänen-Kiukaanniemi S, Valle TT, Uusitupa M, Lindström J, Kolb H, Tuomilehto J. 2006. Diabetes. 55: 2340-2346

Tyypin 2 diabetes on ehkäistävissä ja niksit ovat tiedossa

Uusitupa M, Tuomilehto J. 2006. Duodecim

An autosome-wide scan for linkage disequilibrium-based association in sporadic breast cancer cases in Eastern Finland: three candidate regions found

Hartikainen JM, Tuhkanen H, Kataja V, Dunning AM, Antoniou A, Smith P, Arffman A, Pirskanen M, Easton DF, Eskelinen M, Uusitupa M, Kosma V-M, Mannermaa A. 2005. Cancer epidemiology biomarkers and prevention. 14: 75-80

Antibodies against oxidized LDL and cardiolipin and mortality in patients with coronary heart disease

Erkkilä AT, Närvänen O, Lehto S, Uusitupa MIJ, Ylä-Herttuala S. 2005. Atherosclerosis. 183: 157-162

Antropometriset mittaukset

Uusitupa M, Fogelholm M. Teoksessa: Aro A, Mutanen M, Uusitupa M(toim.) , 2005. Ravitsemustiede. 2. uud. p.. s. 276-281. Duodecim

Gene-diet interaction in relation to the prevention of obesity and type 2 diabetes: Evidence from the Finish diabetes prevention study

Uusitupa M, Uusitupa M. 2005. Nutrition metabolism and cardiovascular diseases. 15: 225-233

Genetic variation in leptin receptor gene is associated with type 2 diabetes and body weight: The Finnish diabetes prevention study

Salopuro T, Pulkkinen L, Lindström J, Eriksson JG, Valle TT, Hämäläinen H, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Tuomilehto J, Laakso M, Uusitupa M, for the Finnish Diabetes Prevention Study Group, Salopuro T, Pulkkinen L, Uusitupa M, Laakso M. 2005. International journal of obesity. 29: 1245-1251

Improved fibrinolysis by an intensive lifestyle intervention in subjects with impaired glucose tolerance. The Finnish diabetes prevention study

Hämäläinen H, Rönnemaa T, Virtanen A, Lindström J, Eriksson JG, Valle TT, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Rastas M, Aunola S, Uusitupa M, TuomilehtoJ, on behalf of the Finnish Diabetes Prevention Study Group. 2005. Diabetologia. 48: 2248-2253

Kehon koostumuksen arviointi

Fogelholm M, Uusitupa M. Teoksessa: Aro A, Mutanen M, Uusitupa M(toim.) , 2005. Ravitsemustiede. 2. uud. p.. s. 282-290. Duodecim

Lihavuus

Uusitupa M. Teoksessa: Aro A, Mutanen M, Uusitupa M(toim.) , 2005. Ravitsemustiede. 2. uud. p.. s. 369-393. Duodecim

Liikunta, energiankulutus ja ravitsemus

Uusitupa M. Teoksessa: Vuori I, Taimela S, Kujala U(toim.) , 2005. Liikuntalääketiede. 3. uud. p.. s. 60-75. Duodecim

Muuttaako lihavuusepidemia kansanterveytemme kehityssuunnan

Uusitupa M. 2005. Elintarvike ja Terveys. : 22-24

NAT2 slow acetylator genotype as an important modifier of breast cancer risk

Sillanpää P, Hirvonen A, Kataja V, Eskelinen M, Kosma V-M, Uusitupa M, Vainio H, Mitrunen K. 2005. International journal of cancer. 114: 579-584

Nuorten nopea lihominen hätkähdyttää

Laitinen J, Uusitupa M. 2005. Lääkärilehti

Nutrigenomiikka - avain ravintotekijöiden molekulaaristen vaikutusten selvittämiseen. Ravinnon ja perintötekijöiden yhteisvaikutusten salat julki

Kolehmainen M, Poutanen K, Uusitupa M, Poutanen K. 2005. Duodecim

Physical activity in the prevention of type 2 diabetes. The Finnish diabetes prevention study

Laaksonen DE, Lindström J, Lakka TA, Eriksson JG, Niskanen L, Wikström K, Aunola S, Keinänen-Kiukaanniemi S, Laakso M, Valle TT, Ilanne-Parikka P, Louheranta A, Hakumäki M, Kaikkonen H, Härkönen P, Sundvall J, Tuomilehto J, Uusitupa M, Louheranta A. 2005. Diabetes. 54: 158-165

Polymorphisms in the SLC2A2 (GLUT2) gene are associated with the conversation from impaired glucose tolerance to type 2 diabetes.The Finnish diabetes prevention study

Laukkanen O, Lindström J, Eriksson J, Valle TT, Hämäläinen H, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Tuomilehto J, Uusitupa M, Laakso M, Laakso M. 2005. Diabetes. 54: 2256-2260

Ravitsemus ja diabetes

Uusitupa M. Teoksessa: Aro A, Mutanen M, Uusitupa M(toim.) , 2005. Ravitsemustiede. 2. uud. p.. s. 394-424. Duodecim

Ravitsemustilan arviointi

Uusitupa M, Fogelholm M. Teoksessa: Aro A, Mutanen M, Uusitupa M(toim.) , 2005. Ravitsemustiede. 2. uud. p.. s. 291-296. Duodecim

Sokeri ja diabetes - onko syytä kiristää suitsia?

Uusitupa M, Uusitupa M. 2005. Lääkärilehti. 60: 1557-1558

Subtle hyperproinsulinaemia characterises the defective insulin secretory capacity in offspring of glutamic acid decarboxylase antibody-positive patients with latent autoimmune diabetes mellitus in adults

Vauhkonen I, Niskanen L, Knip M, Moilanen Mykkänen L, Uusitupa M, Laakso M. 2005. European journal of endocrinology. 153: 265-273

Sulfotransferase 1A1 genotype as a potential modifier of breast cancer risk among premenopausal women

Sillanpää P, Kataja V, Eskelinen M, Kosma V-M, Uusitupa M, Vainio H, Mitrunen K, Hirvonen A. 2005. Pharmacogenetics and genomics. 15: 749-752

XRCC1 and XPD genetic polymorphisms, smoking and breast cancer risk in the Finnish case-control study

Metsola K, Kataja V, Sillanpää P, Siivola P, Heikinheimo L, Eskelinen M, Kosma V-M, Uusitupa M, Hirvonen A. 2005. Breast cancer research. 7: R987-R997

Aldose reductase gene polymorphisms and peripheral nerve function in patients with type 2 diabetes

Sivenius K, Pihlajamäki J, Partanen J, Niskanen L, Laakso M, Uusitupa M. 2004. Diabetes care. 27: 2021-2026

Aldose reductase gene polymorphisms and susceptibility to microvascular complications in type 2 diabetes

Sivenius K, Niskanen L, Voutilainen-Kaunisto R, Laakso M, Uusitupa M. 2004. Diabetic medicine. 21: 1325-1333

Association between a deletion/insertion polymorphism in the alfa2B-adrenergic receptor gene and insulin secretion and type 2 diabetes. The Finnish diabetes prevention study

Siitonen N, Lindström J, Eriksson J, Valle TT, Hämäläinen H, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Tuomilehto J, Laakso M, Uusitupa M. 2004. Diabetologia. 47: 1416-1424

Common polymorphisms in the genes regulating the early insulin signalling pathway: effects on weight change and the conversion from impaired glucose tolerance to Type 2 diabetes

Laukkanen O, Pihlajamäki J, Lindström J, Eriksson J, Valle TT, Hämaläinen H, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Tuomilehto J, Uusitupa M, Laakso M, for the Finnish Diabetes Prevention Study Group, Laakso M. 2004. Diabetologia. 47: 871-877

Common variants in beta2- and beta3-adrenergic receptor genes and uncoupling protein 1 as predictors of the risk for type 2 diabetes and body weight changes. The Finnish diabetes prevention study

Salopuro T, Lindström J, Eriksson JG, Hämäläinen H, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Tuomilehto J, Laakso M, Uusitupa M, Finnish Diabetes Preventio Study Group. 2004. Clinical genetics

Comparative evaluation of simple indices of insulin resistance

Vaccaro O, Masulli M, Vincenzo C, Rivellese AA, Uusitupa M, Vessby B, Hermansen K, Tapsell L, Riccardi G. 2004. Metabolism: clinical and experimental. 53: 1522-1526

Dyslipidemiat

Suomen Sisätautilääkärien Yhdistys ry:n asettama työryhmä, Gylling H, Uusitupa M, Laakso M. 2004. Duodecim. 120: 1794-1816

Elämäntapamuutokset korjaavat pysyvästi insuliiniresistenssia heikentyneessä sokerinsiedossa

Uusitupa M, Lindi V, Louheranta A, Salopuro T, Lindström J, Tuomilehto J, Salopuro T. 2004. Duodecim. 120: 1495-1497

Epidemiology and treatment of the metabolic syndrome

Laaksonen DE, Niskanen L, Lakka H-M, Lakka TA, Uusitupa M, Laaksonen DE. 2004. Annals of medicine. 36: 332-346

Evidence-based nutritional approaches to treatment and prevention of diabetes mellitus

Mann JI, De Leeuw I, Hermansen K, Karamanos B, Karlström B, Katsilamros N, Riccardi G, Rivellese AA, Rizkalla S, Slama G, Toeller M, Uusitupa M, Vessby B, on behalf of the (DNSG) of the (EASD). 2004. Nutrition metabolism and cardiovascular diseases. 14: 373-394

Interactions between peroxisome proliferator-activated receptor-gamma 2 gene polymorphisms and size at birth on blood pressure and the use of antihypertensive medication

Yliharsila H, Eriksson JG, Forsen T, Laakso M, Uusitupa M, Osmond C, Barker DJ, Laakso M. 2004. Journal of hypertension. 22: 1283-1287

Leucine7 to proline7 polymorphism in prepro-NPY gene and femoral neck bone mineral density in postmenopausal women

Heikkinen A-M, Niskanen LK, Salmi JA, Koulu M, Pesonen U, Uusitupa MIJ, Komulainen MH, Tuppurainen MT, Kröger H, Jurvelin J, Saarikoski S, Kröger H. 2004. Bone. 35: 589-594

Long-term results, late complications and quality of life in a series of adjustable gastric banding

Martikainen T, Pirinen E, Alhava E, Poikolainen E, Pääkkönen M, Uusitupa M, Gylling H. 2004. Obesity surgery. 14: 648-654

Perinnöllisen kombinoituneen hyperlipidemian (FKH) geneettinen tausta - rengas kiristyy

Uusitupa M. 2004. Duodecim

Polymorphisms of the SUR1 (ABCC8) and Kir6.2 (KCNJ11) genes predict the conversion from impaired glucose tolerance to type 2 diabetes. The Finnish diabetes prevention study

Laukkanen O, Pihlajamäki J, Lindström J, Eriksson J, Valle TT, Hämäläinen H, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Tuomilehto J, Uusitupa M, Laakso M, for the Finnish diabetes prevention study group. 2004. Journal of clinical endocrinology and metabolism. 89: 6286-6290

Prevalence of the metabolic syndrome and its components. Finding from a Finnish general population sample and the diabetes prevention study cohort

Ilanne-Parikka P, Eriksson JG, Lindström J, Hämäläinen H, Keinänen-Kiukaanniemi S, Laakso M, Louheranta A, Mannelin M, Rastas M, Salminen V, Aunola S, Sundvall J, Valle T, Lahtela J, Uusitupa M, Tuomilehto J. 2004. Diabetes care. 27: 2135-2140

Ravitsemus- ja liikuntasuositukset linjaavat tervytemme perustan

Uusitupa M. 2004. Lääkärilehti

The G-250A promoter polymorphism of the hepatic lipase gene predicts the conversion from impaired glucose tolerance to type 2 diabetes mellitus: the Finnish Diabetes Prevention Study

Todorova B, Kubaszek A, Pihlajamäki J, Lindström J, Eriksson J, Valle TT, Hämäläinen H, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Tuomilehto J, Uusitupa M, Laakso M, Laakso M. 2004. Journal of clinical endocrinology and metabolism. 89: 2019-2023

The effect of meat products enriched with plant sterols and minerals on serum lipids and blood pressure

Tapola NS, Lyyra ML, Karvonen HM, Uusitupa MI, Sarkkinen ES. 2004. International journal of food sciences and nutrition. 55: 389-397

Vitamin D receptor gene polymorphism as an important modifier of positive family history related breast cancer risk

Sillanpää P, Hirvonen A, Kataja V, Eskelinen M, Kosma V-M, Uusitupa M, Vainio H, Mitrunen K. 2004. Pharmacogenetics and genomics. 14: 239-245

A deletion in the alfa2B-adrenergic receptor gene and autonomic nervous function in central obesity

Sivenius K, Niskanen L, Laakso M, Uusitupa M, Laakso M. 2003. Obesity. 11: 962-970

Aineenvaihdunnan ja ravitsemuksen häiriöt

Uusitupa M. Teoksessa: Koskenvuo K(toim.) , 2003. Sairauksien ehkäisy. 2. uud. p.. s. 208-215. Duodecim

Aivojen kuvantaminen syömishäiriöiden ja lihavuuden tutkimuksessa

Karhunen L, Kuikka JT, Uusitupa M. 2003. Duodecim. 119: 859-865

Association of the PRO12ALA polymorphism of the PPAR-gamma2 gene with oxidized low-density lipoprotein and cardiolipin autoantibodies in nondiabetic and type 2 diabetic subjects

Niskanen L, Lindi V, Erkkilä A, Sivenius K, Luoma J, Ylä-Herttuala S, Laakso M, Uusitupa MIJ, Laakso M. 2003. Metabolism: clinical and experimental. 52: 213-217

Diabetes

Uusitupa M. Teoksessa: Koskenvuo K(toim.) , 2003. Sairauksien ehkäisy. 2. uud. p.. s. 216-225. Duodecim

Effect of the pro12ala polymorphism in the peroxisome proliferator-activated receptor (PPAR) gamma2 gene on the expression of PPARgamma target genes in adipose tissue of massively obese subjects

Kolehmainen M, Uusitupa MIJ, Alhava E, Laakso M, Vidal H, Laakso M. 2003. Journal of clinical endocrinology and metabolism. 88: 1717-1722

Effects of dietary saturated, monounsaturated and n-3 fatty acids on fasting lipoproteins, LDL size and post-prandial lipid metabolism in healthy subjects

Rivellese AA, Maffettone A, Vessby B, Uusitupa M, Hermansen K, Berglund L, Louheranta A, Meyer BJ, Riccardi G. 2003. Atherosclerosis. 167: 149-158

Efficacy and safety of plant stanols and sterols in the management of blood cholesterol levels

Katan MB, Grundy SM, Jones P, Law M, Miettinen T, Paoletti R, for the Stresa Workshop participants, Gylling H, Uusitupa M. 2003. Mayo Clinic Proceedings. 78: 965-978

Impact of the pro12ala polymorphism of the PPAR-gamma2 gene on serum triacylglycerol response to n - 3 fatty acid supplementation. For the KANWU study group

Lindi V, Schwab U, Louheranta A, Laakso M, Vessby B, Hermansen K, Storlien L, Riccardi G, Rivellese AA, Uusitupa MIJ, for the KANWU Study Group, Laakso M. 2003. Molecular genetics and metabolism. 79: 52-60

Interactions between peroxisome proliferator-activated receptor gene polymorphism and birth length influence risk for type 2 diabetes

Eriksson JG, Osmond C, Lindi V, Uusitupa M, Forsen T, Laakso M, Barker D, Laakso M. 2003. Diabetes care

Intressiristiriidat lääketieteelisen tutkimuksen rahoituksessa.Yhteisillä pelisäännöillä ongelmat vähenevät

Uusitupa M. 2003. Duodecim

Long-term improvement in insulin sensitivity by changing lifestyles of people with impaired glucose tolerance.4-year results from the Finnish diabetes prevention study

Uusitupa M, Lindi V, Louheranta A, Salopuro T, Lindström J, Tuomilehto J, for the Finnish Diabetes Prevention Study Group. 2003. Diabetes. 52: 2532-2538

Prevention of diabetes mellitus in subjects with impaired glucpse tolerance in the Finnish diabetes prevention study: Results from a randomized clinical trial

Lindström J, Eriksson JG, Valle TT, Aunola S, Cepaitis Z, Hakumäki M, Hämäläinen H, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Laakso M, Louheranta A, Mannelin M, Martikkala V, Moltchanov V, Rastas M, Salminen V, Sundvall J, Uusitupa M, Tuomilehto J. 2003. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. SUPPLEMENT. 14: S108-S113

Prolonged corrected QT interval is associated with acute and chronic hyperinsulinemia in nondiabetic subjects

Laitinen T, Vauhkonen I, Niskanen L, Hartikainen J, Uusitupa M, Laakso M. 2003. Diabetes care

Promoter polymorphisms of the TNF-alfa (G-308A) and IL-6 (C-174G) genes predict the conversion from impaired glucose tolerance to type 2 diabetes. The Finnish Diabetes Prevention Study

Kubaszek A, Pihlajamäki J, Komarovski V, Lindi V, Lindström J, Eriksson J, Valle TT, Hämäläinen H, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Tuomilehto J, Uusitupa M, Laakso M, Laakso M. 2003. Diabetes. 52: 1872-1876

The Finnish Diabetes Prevention Study (DPS): Lifestyle intervention and 3-year results on diet and physical activity

Lindström J, Louheranta A, Mannelin M, Rastas M, Salminen V, Eriksson J, Uusitupa M, Tuomilehto J, for the Finnish Diabetes Prevention Study Group. 2003. Diabetes care. 26: 3230-3236

The Leu7Pro polymorphism of the neuropeptide Y gene regulates free fatty acid metabolism

Pihlajamäki J, Karhapää P, Vauhkonen I, Kekäläinen P, Kareinen A, Viitanen L, Pesonen U, Kallio J, Uusitupa M, Laakso M. 2003. Metabolism: clinical and experimental. 52: 643-646

The effect of intensified diet conseling on the diet of hypertensive subjects in primary health care: a 2-year open randomized controlled trial of lifestyle intervention against hypertension in eastern Finland

Korhonen M, Kastarinen M, Uusitupa M, Puska P, Nissinen A. 2003. Preventive medicine. 36: 8-16

The effects of the Pro12Ala polymorphism of the PPARgamma-2 gene on lipid metabolism interact with body size at birth

Eriksson J, Lindi V, Uusitupa M, Forsén T, Laakso M, Osmond C, Barker D, Laakso M. 2003. Clinical genetics. 64: 366-370

Tolerance of symptomatic lactose malabsobers to lactose in milk chocolate

Järvinen RMK, Loukaskorpi M, Uusitupa MIJ. 2003. European journal of clinical nutrition. 57: 701-705

Treatment improves serotonin transporter binding and reduces binge eating

Tammela LI, Rissanen A, Kuikka JT, Karhunen LJ, Bergström KA, Repo-Tiihonen E, Naukkarinen H, Vanninen E, Tiihonen J, Uusitupa M. 2003. Psychopharmacology. 170: 89-93

Uudistuuko psykiatria terveydenhuollossa

Uusitupa M. Teoksessa: Valkonen-Korhonen M, Lehtonen K, Tuovinen T(toim.) , 2003. Mielenterveys uusiutuvana voimavarana. s. 272-276. Helsinki University Press

n-3 fatty acids and 5-y risks of death and cardiovascular disease events in patients with coronary artery disease1-3

Erkkilä AT, Lehto S, Pyörälä K, Uusitupa MIJ. 2003. American journal of clinical nutrition. 78: 65-71

A meta-analytic investigation of linkage and association of common leptin receptor (LEPR) polymorphisms with body mass index an waist circumference

Heo M, Leibel RL, Fontaine KR, Boyer BB, Chung WK, Koulu M, Karvonen MK, Pesonen U, Rissanen A, Laakso M, Uusitupa MIJ, Chagnon Y, Bouchard C, Donohoue PA, Burns TL, Shuldiner AR, Silver K, Andersen RE, Pedersen O, Echwald S, Sorensen TIA, Behn P, Permutt MA, Jacobs KB, Elston RC, Hoffman DJ, Gropp E, Allison DB. 2002. International journal of obesity. 26: 640-646

Anthropometry, bioelectrical impedance and dual-energy X-ray absorptiometry in the assessment of body composition in elderly Finnish women

Haapala I, Hirvonen A, Niskanen L, Uusitupa M, Kröger H, Alhava E, Nissinen A. 2002. Clinical physiology and functional imaging. 22: 383-391

Association of leucine 7 to proline 7 polymorphism in the preproneuropeptide Y with serum lipids in patients with coronary heart disease

Erkkilä AT, Lindi V, Lehto S, Laakso M, Uusitupa MIJ. 2002. Molecular genetics and metabolism. 75: 260-264

Association of the Pro12Ala polymorphism in the PPAR-gamma2 with 3-year incidence of type 2 diabetes and body weight change in the Finnish Diabetes Prevention Study

Lindi VI, Uusitupa MIJ, Lindström J, Louheranta A, Eriksson JG, Valle TT, Hämäläinen H, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Laakso M, Tuomilehto J, for the Finnish Diabetes Prevention Study Group. 2002. Diabetes. 51: 2581-2586

Association of the fatty acid profile of serum lipids with glucose and insulin metabolism during 2 fat-modified diets in subjects with impaired glucose tolerance 1-3

Louheranta AM, Sarkkinen ES, Vidgren HM, Schwab US, Uusitupa MIJ. 2002. American journal of clinical nutrition. 76: 331-337

Betaine supplementation decreases plasma homocysteine concentrations but does not affect body weight, body composition, or resting energy expenditure in human subjets 1,2,3

Schwab U, Törrönen A, Toppinen L, Alftan G, Saarinen M, Aro A, Uusitupa M. 2002. American journal of clinical nutrition. 76: 961-967

Combined COMT and GST genotypes and hormone replacement therapy associated breast cancer risk

Mitrunen K, Kataja V, Eskelinen M, Kosma V-M, Kang D, Benhamou S, Vainio H, Uusitupa M, Hirvonen A. 2002. Pharmacogenetics and genomics. 12: 67-72

Effect of alfa-linolenic acid-rich camelina sativa oil on serum fatty acid composition and serum lipids in hypercholesterolemic subjects

Karvonen HM, Aro A, Tapola NS, Salminen I, Uusitupa MIJ, Sarkkinen ES. 2002. Metabolism: clinical and experimental. 51: 1253-1260

Elämäntapamuutokset tehokkaita tyypin 2 diabeteksen ehkäisyssä. Diabetes prevention study, DPS

Valle TT, Lindström J, Eriksson JG, Hämäläinen H, Parikka P-I, Keinänen-Kiukaanniemi S, Louheranta A, Laakso M, Martikkala V, Rastas M, Salminen V, Aunola S, Hakumäki M, Mannelin M, Sundvall J, Uusitupa M, Tuomilehto J. 2002. Lääkärilehti. 57: 1369-1377

Hormone sensitive lipase expression and adipose tissue metabolism show gender difference in obese subjects after weight loss

Kolehmainen M, Vidal H, Ohisalo JJ, Pirinen E, Alhava E, Uusitupa MIJ. 2002. International journal of obesity. 26: 6-16

Iris transluminance in type 2 diabetes

Voutilainen-Kaunisto R, Niskanen L, Uusitupa M, Teräsvirta M. 2002. Acta ophthalmologica. 80: 64-68

Lifestyle intervention in the prevention of type 2 diabetes

Uusitupa M. 2002. DIABETES AND RELATED DISORDERS

Lifestyles matter in the prevention of type 2 diabetes

Uusitupa M. 2002. Diabetes care

Lihavuus ja ahmimishäiriö

Rissanen A, Uusitupa M. Teoksessa: Neuvonen PJ , Himberg J-J, Huupponen R, Kivistö KT, Ylitalo P(toim.) , 2002. Kliininen farmakologia ja lääkehoito. s. 428-434. Kandidaattikustannus

N-3-sarjan rasvahapot suojaavat sepelvaltimotautipotilasta äkkikuolemalta

Erkkilä A, Uusitupa M. 2002. Duodecim

No harm from five year ingestion of oats in coeliac disease

Janatuinen EK, Kemppainen TA, Julkunen RJK, Kosma V-M, Mäki M, Heikkinen M, Uusitupa MIJ. 2002. Gut. 50: 332-335

Non-pharmacological treatment of hypertension in primary health care: a 2-year open randomized controlled trial of lifestyle intervention against hypertension in eastern Finland

Kastarinen MJ, Puska PM, Korhonen MH, Mustonen JN, Salomaa VV, Sundvall JE, Tuomilehto JO, Uusitupa MI, Nissinen AM, for the LIHEF Study Group. 2002. Journal of hypertension. 20: 2505-2512

Ravintotekijät säätelevät geenien toimintaa

Hendolin M, Uusitupa M. 2002. Kehittyvä Elintarvike. : 6-7

Short-term LDL cholesterol-lowering efficacy of plant stanol esters

Hallikainen M, Sarkkinen E, Wester I, Uusitupa M. 2002. Bmc cardiovascular disorders. 2: 1-14

The effect of vegetable oil-based cheese on serum total and lipoprotein lipids

Karvonen HM, Tapola NS, Uusitupa MI, Sarkkinen ES. 2002. European journal of clinical nutrition. 56: 1094-1101

The effects of the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma2 gene on insulin sensitivity and insulin metabolism interact with size at birth

Eriksson JG, Lindi V, Uusitupa M, Forsén TJ, Laakso M, Osmond C, Barker DJP. 2002. Diabetes. 51: 2321-2324

The impact of the leucine 7 to proline 7 polymorphism of the neuropeptide Y gene on postprantial lipemia and on the response of serum total and lipoprotein lipids to a reduced fat diet

Schwab US, Ågren JJ, Valve R, Hallikainen MA, Sarkkinen ES, Jauhiainen M, Karvonen MK, Pesonen U, Koulu M, Uusitupa MIJ, Savolainen MJ. 2002. European journal of clinical nutrition. 56: 149-156

Variation in the fatty acid binding protein 2 gene is not associated with markers of metabolic syndrome in patients with coronary heart disease

Erkkilä AT, Lindi V, Lehto S, Pyörälä K, Laakso M, Uusitupa MIJ. 2002. Nutrition metabolism and cardiovascular diseases. 12: 53-59

APOE polymorphism and the hypertriglyceridemic effect of dietary sucrose 1-3

Erkkilä AT, Sarkkinen ES, Lindi V, Lehto S, Laakso M, Uusitupa MIJ. 2001. American journal of clinical nutrition. 73: 746-752

Aikuistyypin diabeteksen ehkäisy - haaste terveydenhuollollemme

Uusitupa M. 2001. DIABETES JA LÄÄKÄRI. 30: 6-7

Altered intracellular processing and release of neuropeptide Y due to leucine 7 to proline 7 polymorphism in the signal peptide of preproneuropeptide Y in humans

Kallio J, Pesonen U, Kaipio K, Karvonen MK, Jaakkola U, Heinonen OJ, Uusitupa MIJ, Koulu M. 2001. Faseb journal. 15: 1242-1244

Association between manganese superoxide dismutase (MnSOD) gene polymorphism and breast cancer risk

Mitrunen K, Sillanpää P, Kataja V, Eskelinen M, Kosma V-M, Benhamou S, Uusitupa M, Hirvonen A. 2001. Carcinogenesis. 22: 827-829

Clustering of cardiovascular risk factors in type 2 diabetes mellitus: prognostic significance and tracking

Kaukua J, Turpeinen A, Uusitupa M, Niskanen L. 2001. Diabetes obesity and metabolism. 3: 17-23

D-vitamiini ja eturauhassyöpä

Järvinen R, Uusitupa M. 2001. Lääkärilehti. 56: 3211-3212

Effect of a three-amino acid deletion in the alfa2B-adrenergic receptor gene on long-term body weight change in Finnish non-diabetic and type 2 diabetic subjects

Sivenius K, Lindi V, Niskanen L, Laakso M, Uusitupa M. 2001. International journal of obesity. 25: 1609-1614

Effect of the Pro12Ala polymorphism of the PPAR-gamma2 gene on lon-term weight change in Finnish non-diabetic subjects

Lindi V, Sivenius K, Niskanen L, Laakso M, Uusitupa MIJ. 2001. Diabetologia

Effects of ageing on serotonin transporters in healthy females

Kuikka JT, Tammela L, Bergström KA, Karhunen L, Uusitupa M, Tiihonen J. 2001. European journal of nuclear medicine and molecular imaging. 28: 911-913

Glutathione S-transferase M1, M3, P1, and T1 genetic polymorphisms and susceptibility to breast cancer

Mitrunen K, Jourenkova N, Kataja V, Eskelinen M, Kosma V-M, Benhamou S, Vainio H, Uusitupa M, Hirvonen A. 2001. Cancer epidemiology biomarkers and prevention. 10: 229-236

Leucine7 to proline7 polymorphism in the preproneuropeptide Y is associated with the progression of carotid atherosclerosis, blood pressure and serum lipids in Finnish men

Karvonen MK, Valkonen V-P, Lakka TA, Salonen R, Koulu M, Pesonen U, Tuomainen T-P, Kauhanen J, Nyyssönen K, Lakka H-M, Uusitupa MIJ, Salonen JT. 2001. Atherosclerosis. 159: 145-151

Liikunta ja ruokavalio ovat metabolisen oireyhtymän täsmähoitoa

Uusitupa M. 2001. Duodecim. 117: 621-630

Maculopathy and visual acuity in newly diagnosed type 2 diabetic patients and non-diabetic subjects: A 10-year follow-up study

Voutilainen-Kaunisto R, Teräsvirta M, Uusitupa M, Niskanen L. 2001. Acta ophthalmologica. 79: 163-168

Myocardial fatty acid oxidation in patients with impaired glucose tolerance

Knuuti J, Takala TO, Någren K, Sipilä H, Turpeinen AK, Uusitupa MIJ, Nuutila P. 2001. Diabetologia. 44: 184-187

Occurrence and predictors of retinopathy and visual acuity in type 2 diabetic patients and control subjects 10-year follow-up from the diagnosis

Voutilainen-Kaunisto RM, Teräsvirta ME, Uusitupa MIJ, Niskanen LK. 2001. Journal of diabetes and its complications. 15: 24-33

Polymorphic GSTs and cancer predisposition

Hirvonen A, Bouchardy C, Mitrunen K, Kataja V, Eskelinen M, Kosma V-M, Saarikoski ST, Jourenkova N, Anttila S, Dayer P, Uusitupa M, Benhamou S. 2001. Chemico-biological interactions. 133: 75-80

Polymorphic catechol-O-methyltransferase gene and breast cancer risik

Mitrunen K, Jourenkova N, Kataja V, Eskelinen M, Kosma V-M, Benhamou S, Kang D, Vainio H, Uusitupa M, Hirvonen A. 2001. Cancer epidemiology biomarkers and prevention. 10: 635-640

Postprandial responses of individual fatty acids in subjects homozygous for the threonine- or alanine-encoding allele in codon 54 of the intestinal fatty acid binding protein 2 gene 1,2

Ågren JJ, Vidgren HM, Valve RS, Laakso M, Uusitupa MI. 2001. American journal of clinical nutrition. 73: 31-35

Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance

Tuomilehto J, Lindström J, Eriksson JG, Valle TT, Hämäläinen H, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Laakso M, Louheranta A, Rastas M, Salminen V, Uusitupa M, for the Finnish Diabetes Prevention Study Group, Hakumäki M. 2001. The new england journal of medicine. 344: 1343-1350

Reduced serotonin transporter binding in binge eating women

Kuikka JT, Tammela L, Karhunen L, Rissanen A, Bergström KA, Naukkarinen H, Vanninen E, Karhu J, Lappalainen R, Repo-Tiihonen E, Tiihonen J, Uusitupa M. 2001. Psychopharmacology. 155: 310-314

Serum enterolactone and risk of breast cancer: A case-control study in Eastern Finland

Pietinen P, Stumpf K, Männistö S, Kataja V, Uusitupa M, Adlercreutz H. 2001. Cancer epidemiology biomarkers and prevention. 10: 339-344

Sterol regulatory element binding protein 1c (SREBP-1c) expression in human obesity

Kolehmainen M, Vidal H, Alhava E, Uusitupa MIJ. 2001. Obesity. 9: 706-712

Substituting dietary saturated for monounsaturated fat impairs insulin sensitivity in healthy men and women:The KANWU study

Vessby B, Uusitupa M, Hermansen K, Riccardi G, Rivellese AA, Tapsell LC, Nälsén C, Berglund L, Louheranta A, Rasmussen BM, Calvert GD, Maffetone A, Pedersen E, Gustafsson I-B, Storlien LH. 2001. Diabetologia. 44: 312-319

Tyypin 2 diabetes on ehkäistävissä elämäntapamuutoksilla

Valle TT, Lindström J, Eriksson JG, Uusitupa M, Tuomilehto J. 2001. Duodecim

Weight change and blood coagulability and fibrinolysis in healthy obese women

Rissanen P, Vahtera E, Krusius T, Uusitupa M, Rissanen A. 2001. International journal of obesity. 25: 212-218

Yhteistyö sairaanhoitopiirien välillä Suomessa

Uusitupa M, Tuomainen R. 2001. Lääkärilehti. 56: 683-687

Aerobic exercise and the lipid profile in type 1 diabetic men: a randomized controlled trial

Laaksonen DE, Atalay M, Niskanen LK, Mustonen J, Sen CK, Lakka TA, Uusitupa MIJ. 2000. Medicine and science in sports and exercise. 32: 1541-1548

Age-related macular degeneration in newly diagnosed type 2 diabetic patients and control subjects

Voutilainen-Kaunisto RM, Teräsvirta ME, Uusitupa MIJ, Niskanen LK. 2000. Diabetes care. 23: 1672-1678

Aikuistyypin diabeteksen ehkäisy

Louheranta A, Uusitupa M. 2000. Lääkärilehti. 55: 3919-3921

Autoantibodies against oxidized low-density lipoprotein and cardiolipin in patients with coronary heart disease

Erkkilä AT, Närvänen O, Lehto S, Uusitupa MIJ, Ylä-Herttuala S. 2000. Arteriosclerosis, thrombosis, and vascular biology. 20: 204-209

Comparison of the effects of plant sterol ester and plant stanol ester-enriched margarines in lowering serum cholesterol concentrations in hypercholesterolaemic subjects on low-fat diet

Hallikainen MA, Sarkkinen ES, Gylling H, Erkkilä AT, Uusitupa MIJ. 2000. European journal of clinical nutrition. 54: 715-725

Concordance of in vivo microdialysis and in vitro techniques in the studies of adipose tissue metabolism

Kolehmainen M, Ohisalo JJ, Kaartinen JM, Tuononen V, Pääkkönen M, Poikolainen E, Alhava E, Uusitupa MIJ. 2000. International journal of obesity. 24: 1426-1432

Effect of orlistat treatment on body composition and resting energy expenditure during a two-year weight -reduction programme in obese Finns

Karhunen L, Franssila-Kallunki A, Rissanen P, Valve R, Kolehmainen M, Rissanen A, Uusitupa M. 2000. International journal of obesity. 24: 1567-1572

Effects of a salt-restricted diet on the intake of other nutrients

Korhonen MH, Järvinen RMK, Sarkkinen ES, Uusitupa MIJ. 2000. American journal of clinical nutrition. 72: 414-420

Growth, dietary intake, and trace element status in pubescent athletes and schoolchildren

Fogelholm M, Rankinen T, Isokääntä M, Kujala U, Uusitupa M. 2000. Medicine and science in sports and exercise. 32: 738-746

Health effects of plant stanol esters

Hallikainen M, Sarkkinen E, Uusitupa M. 2000. FOOD INDUSTRY JOURNAL. 3: 232-238

Hyperproinsulinemia is not a charascteristic feature in the offspring of patients with different phenotypes of type II diabetes

Vauhkonen IKJ, Niskanen LK, Mykkänen L, Haffner SM, Uusitupa MIJ, Laakso M. 2000. European journal of endocrinology. 143: 251-260

Impaired insulin secretion in non-diabetic offspring of probands with latent autoimmune diabetes mellitus in adults

Vauhkonen I, Niskanen L, Knip M, Ilonen J, Vanninen E, Kainulainen S, Uusitupa M, Laakso M. 2000. Diabetologia. 43: 69-78

Insulin sensitivity after a reduced-fat diet and a monoene-ecriched idiet in subjects with elevated serum cholesterol and triglyceride concentrations

Louheranta AM, Schwab US, Sarkkinen ES, Voutilainen ET, Ebeling TML, Erkkilä AT, Turpeinen AK, Uusitupa MIJ. 2000. Nutrition metabolism and cardiovascular diseases. 10: 177-187

Kaura ja keliakia. Pitkäaikaistulokset varmistavat kauran sopivuuden

Uusitupa M, Kemppainen T. 2000. Lääkärilehti. 55: 1868-1869

Lack of cellular and humoral immunological responses to oats in adults with coeliac disease

Janatuinen EK, Kemppainen TA, Pikkarainen PH, Holm KH, Kosma V-M, Uusitupa MIJ, Mäki M, Julkunen RJK. 2000. Gut. 46: 327-331

Leucine 7 to proline 7 polymorphism in the neuropeptide Y gene is associated with enhanced carotid atherosclerosis in elderly patients with type 2 diabetes and control subjects

Niskanen L, Karvonen MK, Valve R, Koulu M, Pesonen UM, Mercuri M, Rauramaa R, Töyry J, Laakso M, Uusitupa MIJ. 2000. Journal of clinical endocrinology and metabolism. 85: 2266-2269

Leucine 7 to proline 7 polymorphism in the neuropeptide y gene is associated with retinopathy in Type 2 diabetes

Niskanen L, Voutilainen-Kaunisto R, Teräsvirta M, Karvonen M K, Valve R, Pesonen U, Laakso M, Uusitupa MIJ, Koulu M. 2000. Experimental and clinical endocrinology and diabetes. 108: 235-236

Leucine 7 to proline 7 polymorphism in the preproneuropeptide Y is associated with birth weight and serum triglyceride concentration in preschoolaged children

Karvonen MK, Koulu M, Pesonen U, Uusitupa MIJ, Tammi A, Viikari J, Simell O, Rönnemaa T. 2000. Journal of clinical endocrinology and metabolism. 85: 1455-1460

Lifetime alcohol consumption and breast cancer: a case-control study in Finland

Männistö S, Virtanen M, Kataja V, Uusitupa M, Pietinen P. 2000. Public health nutrition. 3: 11-18

Long-term effect of acetyl-L-carnitine on myocardial 123I-MIBG uptake in patients with diabetes

Turpeinen AK, Kuikka JT, Vanninen E, Yang J, Uusitupa MIJ. 2000. Clinical autonomic research. 10: 13-16

Neuropeptide Y polymorphism and alcohol consumption in middle-aged men

Kauhanen J, Karvonen MK, Pesonen U, Koulu M, Tuomainen T-P, Uusitupa MIJ, Salonen JT. 2000. American journal of medical genetics. Part A. 93: 117-121

Onko suklaa terveellistä?

Sarkkinen E, Uusitupa M. 2000. Lääkärilehti. 55: 2902-2903

Oral symptoms and signs in elderly patients with type 2 diabetes mellitus. A focus on diabetic neuropathy

Collin H-L, Niskanen L, Uusitupa M, Töyry J, Collin P, Koivisto A-M, Viinamäki H, Meurman JH. 2000. Oral surgery oral medicine oral pathology oral radiology and endodontology. 90: 299-305

Plant stanol esters affect serum cholesterol concentrations of hyperchlesterolemic men and women in a done-dependent manner

Hallikainen MA, Sarkkinen ES, Uusitupa MIJ. 2000. Journal of nutrition. 130: 767-776

Recommendations for the nutritional management of patients with diabetes mellitus

The Diabetes and Nutrition Study Group of the EASD, Uusitupa M. 2000. European journal of clinical nutrition. 54: 353-355

Regional cerebral blood flow during exposure to food in obese binge eating women

Karhunen LJ, Vanninen EJ, Kuikka JT, Lappalainen RI, Tiihonen J, Uusitupa MIJ. 2000. Psychiatry research: neuroimaging. 99: 29-42

Salivary matrix metalloproteinase (MMP-8) levels and gelatinase (MMP-9) activities in patients with type 2 diabetes mellitus

Collin H-L, Sorsa T, Meurman JH, Niskanen L, Salo T, Rönkä H, Konttinen YT, Koivisto A-M, Uusitupa M. 2000. Journal of periodontal research. 35: 259-265

Stanolia, sterolia - mutta kuinka paljon?

Sarkkinen E, Hallikainen M, Uusitupa M. 2000. Lääkärilehti. 55: 846-847

Steroid metabolism gene CYP17 polymorpsm and the develpment of breast cancer

Mitrunen K, Jourenkova N, Kataja V, Eskelinen M, Kosma V-M, Benhamou S, Vainio H, Uusitupa M, Hirvonen A. 2000. Cancer epidemiology biomarkers and prevention. 9: 1343-1348

Sydänmerkki tutuksi

Uusitupa M. 2000. Lääkärilehti

Synergistic effect of polymorphisms in uncoupling protein 1 and beta3-adrenergic receptor genes on long-term body weight chance in Finnish type 2 diabetic and non-diabetic control subjects

Sivenius K, Valve R, Lindi V, Niskanen L, Laakso M, Uusitupa M. 2000. International journal of obesity. 24: 514-519

The Finnish Diabetes Prevention Study

Uusitupa M, Louheranta A, Lindström J, Valle T, Sundvall J, Eriksson J, Tuomilehto J, on behalf of the Finnish Diabetes Prevention Study Group. 2000. BRITISH JOURNAL OF NUTRITION. SUPPLEMENT. 83: S137-S142

The leucine (7)-to-proline (7) polymorphism in the signal peptide of neuropeptide y is not associated with Alzheimer¿s disease or the link apolipoprotein E

Helisalmi S, Valve R, Karvonen MK, Hiltunen M, Pirskanen M, Mannermaa A, Koulu M, Pesonen U, Uusitupa M, Soininen H. 2000. Neuroscience letters. 287: 25-28

Tieteellinen ja kliininen työ - yhdessä vai erikseen?

Uusitupa M. Teoksessa: Voipio-Pulkki L-M, Grenman R, Haapamäki M, Lenander-Lumikari M, Mäkinen J, Rautava P, Scheinin M, Vainikainen T(toim.) , 2000. Kliinisen tutkijan opas. s. 27-35. Duodecim

Toenail selenium and breast cancer - a case-control study in Finland

Männistö S, Alfthan G, Virtanen M, Kataja V, Uusitupa M, Pietinen P. 2000. European journal of clinical nutrition. 54: 98-103

Variants in the hepatocyte nuclear factor-1alfa and -4alfa genes in Finnish and Chinese subjects with late-onset type 2 diabetes

Rissanen J, Wang H, Miettinen R, Kärkkäinen P, Kekäläinen P, Mykkänen L, Kuusisto J, Karhapää P, Niskanen L, Uusitupa M, Laakso M. 2000. Diabetes care. 23: 1533-1538

A high-trans fatty acid diet and insulin sensitivity in young healthy women

Louheranta AM, Turpeinen AK, Vidgren HM, Schwab US, Uusitupa MIJ. 1999. Metabolism: clinical and experimental. 48: 870-875

Adherence to the salt restriction diet among people with mildly elevated blood pressure

Korhonen MH, Litmanen H, Rauramaa R, Väisänen SB, Niskanen L, Uusitupa MIJ. 1999. European journal of clinical nutrition. 53: 880-885

Antropometriset mittaukset

Uusitupa M, Fogelholm M. Teoksessa: Aro A, Mutanen M, Uusitupa M(toim.) , 1999. Ravitsemustiede. s. 267-272. Duodecim

Blood glutathione homeostasis as a determinant of resting and exercise-induced oxidative stress in young men

Laaksonen DE, Atalay M, Niskanen L, Uusitupa M, Hänninen O, Sen CK. 1999. Redox report. 4: 53 - 59

Bone recovery after a gluten-free diet: a 5-year follow-up study

Kemppainen T, Kröger H, Janatuinen E, Arnala I, Lamberg-Allardt C, Kärkkäinen M, Kosma V-M, Julkunen R, Jurvelin J, Alhava E, Uusitupa M. 1999. Bone. 25: 355-360

Diet and the risk of breast cancer in a case-control study: does the threat of disease have an influence on recall bias?

Männistö S, Pietinen P, Virtanen M, Kataja V, Uusitupa M. 1999. Journal of clinical epidemiology. 52: 429-439

Diet in relation to socioeconomic status in patients with coronary heart disease

Erkkilä AT, Sarkkinen ES, Lehto S, Pyörälä K, Uusitupa MIJ. 1999. European journal of clinical nutrition. 52: 662-668

Dietary associates of serum total, LDL, and HDL cholesterol and triglycerides in patients with coronary heart disease

Erkkilä AT, Sarkkinen ES, Lehto S, Pyörälä K, Uusitupa MIJ. 1999. Preventive medicine. 28: 558-565

Difficulties in changing the diet in relation to dietary fat intake among patients with coronary heart disease

Koikkalainen M, Mykkänen H, Erkkilä A, Julkunen J, Saarinen T, Pyörälä K, Uusitupa M, Lappalainen R. 1999. European journal of clinical nutrition. 53: 120-125

Effects of 2 low-fat stanol ester-containing margarines on serum cholesterol concentrations as a part of a low-fat diet in hypercholesterolemic subjects

Hallikainen MA, Uusitupa MIJ. 1999. American journal of clinical nutrition. 69: 403-410

Effects of low-fat stanol ester enriched margarines on concentrations of serum carotenoids in subjects with elevated serum cholesterol concentrations

Hallikainen MA, Sarkkinen ES, Uusitupa MIJ. 1999. European journal of clinical nutrition. 53: 966-969

Efficacy of plant stanol esters in subjects consuming NCEP diets

Uusitupa M, Hallikainen M. 1999. European heart journal supplements. 1: S91-S95

Hyperglykemian lääkehoito ja aikuistyypin diabeteksen ennuste

Niskanen L, Uusitupa M, Laakso M. 1999. Duodecim. 115: 1122-1124

Identification of a three-amino acid deletion in the alfa2B-adrenergic receptor that is associated with reduced basal metabolic rate in obese subjects

Heinonen P, Koulu M, Pesonen U, Karvonen MK, Rissanen A, Laakso M, Valve R, Uusitupa M, Scheinin M. 1999. Journal of clinical endocrinology and metabolism. 84: 2429-2433

Impaired free fatty acid uptake in skeletal muscle but not in myocardium in patients with impaired glucose tolerance Studies with PET and 14(R, S)-[18F]Fluoro-6-Thia-Heptadecanoic acid

Turpeinen AK, Takala TO, Nuutila P, Axelin T, Luotolahti M, Haaparanta M, Bergman J, Hämäläinen H, Iida H, Mäki M, Uusitupa MIJ, Knuuti J. 1999. Diabetes. 48: 1245-1250

Kehon koostumuksen arviointi

Fogelholm M, Uusitupa M. Teoksessa: Aro A, Mutanen M, Uusitupa M(toim.) , 1999. Ravitsemustiede. s. 273-279. Duodecim

Leptin concentrations and their relation to body fat distribution and weight loss - a prospective study in individuals with impaired glucose tolerance

Eriksson J, Valle T, Lindström J, Haffner S, Louheranta A, Uusitupa M, Tuomilehto J, on behalf of the DPS-study group. 1999. Hormone and metabolic research. 31: 616-619

Lihavuus

Uusitupa M. Teoksessa: Aro A, Mutanen M, Uusitupa M(toim.) , 1999. Ravitsemustiede. s. 354-376. Duodecim

Liikunta, energiankulutus ja ravitsemus

Fogelholm M, Uusitupa M. Teoksessa: Vuori I, Taimela S(toim.) , 1999. Liikuntalääketiede. 2., uud. p.. s. 73-82. Duodecim

Measurement of prostate-specific antigen in detection of benign or malignant breast disease in women

Romppanen J, Keskikuru R, Kataja V, Eskelinen M, Kosma V-M, Savolainen K, Uusitupa M, Mononen I. 1999. British journal of cancer. 79: 1583-1587

Neuropeptidi Y ja veren kolesterolipitoisuus

Uusitupa MIJ, Karvonen MK, Pesonen U, Koulu M. 1999. Duodecim

New aspects in the management of obesity: operation and the impact of lipase inhibitors

Uusitupa M. 1999. Current opinion in lipidology. 10: 3-7

Osteoporosis in adult patients with celiac disease

Kemppainen T, Kröger H, Janatuinen E, Arnala I, Kosma V-M, Pikkarainen P, Julkunen R, Jurvelin J, Alhava E, Uusitupa M. 1999. Bone. 24: 249-255

Power spectral analysis of heart rate variability during hyperinsulinemia in nondiabetic offspring of type 2 diabetic patients: evidence for possible early autonomic dysfunction in insulin-resistant subjects

Laitinen T, Vauhkonen IKJ, Niskanen LK, Hartikainen JEK, Länsimies EA, Uusitupa MIJ, Laakso M. 1999. Diabetes. 48: 1295-1299

Preoperative high type I collagen degradation marker ICTP reflects advanced breast cancer

Keskikuru R, Kataja V, Kosma V-M, Eskelinen M, Uusitupa M, Johansson R, Risteli L, Risteli J, Jukkola A. 1999. Anticancer research. 19: 4481-4484

Prevention of type II diabetes in subjects with impaired glucose tolerance:the Diabetes Prevention Study (DPS) in Finland: study design and 1-year interim report on the feasibility of the lifestyle intervention programme

Eriksson J, Lindström J, Valle T, Aunola S, Hämäläinen H, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Laakso M, Lauhkonen M, Lehto P, Louheranta A, Mannelin M, Martikkala V, Rastas M, Sundvall J, Turpeinen A, Viljanen T, Uusitupa M, Tuomilehto J. 1999. Diabetologia. 42: 793-801

Ravitsemus ja diabetes

Uusitupa M. Teoksessa: Aro A, Mutanen M, Uusitupa M(toim.) , 1999. Ravitsemustiede. s. 377-404. Duodecim

Ravitsemustilan arviointi

Uusitupa M, Fogelholm M, Nuutinen L. Teoksessa: Aro A, Mutanen M, Uusitupa M(toim.) , 1999. Ravitsemustiede. s. 280-285. Duodecim

Reply to S Jameson (to Villous atrophy and nutritional status in celiac disease)

Kemppainen TA, Uusitupa MI, Kosma V-M, Julkunen RJ. 1999. American journal of clinical nutrition

Rye bread decreases postprandial insulin response but does not alter glucose response in healthy Finnish subjects

Leinonen K, Liukkonen K, Poutanen K, Uusitupa M, Mykkänen H. 1999. European journal of clinical nutrition. 53: 262-267

Serum leptin and regional cerebral blood flow during exposure to food in obese and normal-weight women

Karhunen LJ, Lappalainen RI, Vanninen EJ, Kuikka JT, Uusitupa MIJ. 1999. Neuroendocrinology. 69: 154-159

Sydän- ja keuhkosairauksien ravitsemushoito

Uusitupa M. Teoksessa: Aro A, Mutanen M, Uusitupa M(toim.) , 1999. Ravitsemustiede. s. 522-523. Duodecim

The effect of orlistat on the fatty acid composition of serum lipid fractions in obese subjects

Vidgren HM, Ågren JJ, Valve RS, Karhunen LJ, Rissanen AM, Uusitupa MIJ. 1999. Clinical pharmacology and therapeutics. 66: 315-322

Two polymorphisms in the peroxisome proliferator-activated receptor-gamma gene are associated with severe overweight among obese women

Valve R, Sivenius K, Miettinen R, Pihlajamäki J, Rissanen A, Deeb SS, Auwerx J, Uusitupa M, Laakso M. 1999. Journal of clinical endocrinology and metabolism. 84: 3708-3712

A high-stearic acid diet does not impair glucose tolerance and insulin sensitivity in healthy women

Louheranta AM, Turpeinen AK, Schwab US, Vidgren HM, Parviainen MT, Uusitupa MIJ. 1998. Metabolism: clinical and experimental. 47: 529-534

Aineenvaihdunnan ja ravitsemuksen häiriöt: diabetes

Uusitupa M. Teoksessa: Koskenvuo K, Vertio H(toim.) , 1998. Sairauksien ehkäisy. s. 177-184. Duodecim

Aineenvaihdunnan ja ravitsemuksen häiriöt: lihavuus

Uusitupa M. Teoksessa: Koskenvuo K, Vertio H(toim.) , 1998. Sairauksien ehkäisy. s. 171-177. Duodecim

Association of a leucine(7)-to-proline(7) polymorphism in the signal peptide of neuropeptide Y with high serum cholesterol and LDL cholesterol levels

Karvonen MK, Pesonen U, Koulu M, Niskanen L, Laakso M, Rissanen A, Dekker JM, ¿T Hart LM, Valve R, Uusitupa MIJ. 1998. Nature medicine. 4: 1434-1437

Caries in patients with non-insulin-dependent diabetes mellitus

Collin H-L, Uusitupa M, Niskanen L, Koivisto A-M, Markkanen H, Meurman JH. 1998. Oral surgery oral medicine oral pathology oral radiology and endodontology. 85: 680-685

Concordance of diet with the recommended cholesterol lowering diet in patients with coronary heart disease

Erkkilä AT, Sarkkinen ES, Koukkunen H, Kemppainen A, Lehto S, Pyörälä K, Uusitupa MIJ. 1998. European journal of clinical nutrition. 52: 279-285

Defects in insulin secretion and insulin action in non-insulin-dependent diabetes mellitus are inherited: metabolic studies on offspring of diabetic probands

Vauhkonen I, Niskanen L, Vanninen E, Kainulainen S, Uusitupa M, Laakso M. 1998. Journal of clinical investigation. 101: 86-96

Divergent incorporation of dietary trans fatty acids in different serum lipid fractions

Vidgren HM, Louheranta AM, Ågren JJ, Schwab US, Uusitupa MIJ. 1998. Lipids. 33: 955-962

Early intervention in obesity: implications for impaired glucose tolerance and type II diabetes

Uusitupa M, Van Gaal L. 1998. EUROPEAN JOURNAL OF CLINICAL INVESTIGATION. SUPPLEMENT

Effect of apolipoprotein E polymorphism on serum lipid response to the separate modification of dietary fat and dietary cholesterol 1-3

Sarkkinen E, Korhonen M, Erkkilä A, Ebeling T, Uusitupa M. 1998. American journal of clinical nutrition. 68: 1215-1222

Fat-modified diets influence serum concentrations of cholesterol precursors and plant sterols in hypercholesterolemic subjects

Sarkkinen ES, Uusitupa MIJ, Gylling H, Miettinen TA. 1998. Metabolism: clinical and experimental. 47: 744-750

Hyperglycemia and compositional lipoprotein abnormalities as predictors of cardiovascular mortality in type 2 diabetes: a 15-year follow-up from the time of diagnosis

Niskanen L, Turpeinen A, Penttilä I, Uusitupa MIJ. 1998. Diabetes care. 21: 1861-1869

Hypo-cholesterolaemic effects of dietary fibre in relation to genetic factors

Uusitupa M. Teoksessa: Guillon E, Amado R et al.(toim.) , 1998. Functional Properties of Non-Digestible Carbohydrates. European Air Concerted Action AIR3CT94-2203. s. 97-100. European Commission

Identification of new sequence variants in the leptin gene

Karvonen MK, Pesonen U, Heinonen P, Laakso M, Rissanen A, Naukkarinen H, Valve R, Uusitupa MIJ, Koulu M. 1998. Journal of clinical endocrinology and metabolism. 83: 3239-3242

Insulin resistant phenotype is associated with high serum leptin levels in offspring of patients with non-insulin-dependent diabetes mellitus

Vauhkonen I, Niskanen L, Haffner S, Kainulainen S, Uusitupa M, Laakso M. 1998. European journal of endocrinology. 139: 598-604

Kost som prevention mot fetma

Uusitupa M. Teoksessa: Andersen T, Rissanen A, Rössner S (red.)(toim.) , 1998. Fetma/fedme - en nordisk lärobok. s. 325-330. Studentlitteratur

Lihavan potilaan tutkiminen ja hoitomuodon valinta

Mustajoki P, Rissanen A, Uusitupa M. Teoksessa: Fogelholm M, Mustajoki P, Rissanen A, Uusitupa M(toim.) , 1998. Lihavuus: ongelma ja hoito. 2. uud. p.. s. 103-107. Duodecim

Lihavuuden syyt

Rissanen A, Uusitupa M. Teoksessa: Fogelholm M, Mustajoki P, Rissanen A, Uusitupa M(toim.) , 1998. Lihavuus: ongelma ja hoito. 2. uud. p.. s. 89-91. Duodecim

Lihavuus ja terveys

Uusitupa M. Teoksessa: Fogelholm M, Mustajoki P, Rissanen A, Uusitupa M(toim.) , 1998. Lihavuus : ongelma ja hoito. 2. uud. p.. s. 19-28. Duodecim

Mäkihyppääjien ravitsemustila - kevyempänä lentää kauemmaksi

Uusitupa M. 1998. Lääkärilehti. 53: 836-837

Neuropeptide Y: a novel link between the neuroendocrine system and cholesterol metabolism

Uusitupa MIJ, Karvonen MK, Pesonen U, Koulu M. 1998. Annals of medicine

Nutritional status of newly diagnosed celiac disease patients before and after the institution of a celiac disease diet - association with the grade of mucosal villous atrophy1-3

Kemppainen TA, Kosma V-M, Janatuinen EK, Julkunen RJ, Pikkarainen PH, Uusitupa MI. 1998. American journal of clinical nutrition. 67: 482-487

Nutritional status of the Finnish elite ski jumpers

Rankinen T, Lyytikäinen S, Vanninen E, Penttilä I, Rauramaa R, Uusitupa M. 1998. Medicine and science in sports and exercise. 30: 1592-1597

Perimä ja lihavuus

Uusitupa M. Teoksessa: Fogelholm M, Mustajoki P, Rissanen A, Uusitupa M(toim.) , 1998. Lihavuus: ongelma ja hoito. 2. uud. p.. s. 60-69. Duodecim

Periodontal findings in elderly patients with non-insulin dependent diabetes mellitus

Collin H-L, Uusitupa M, Niskanen L, Kontturi-Närhi V, Markkanen H, Koivisto A-M, Meurman JH. 1998. Journal of periodontology. 69: 962-966

Postprandial lipemic response is modified by the polymorphism at codon 54 of the fatty acid-binding protein 2 gene

Ågren JJ, Valve R, Vidgren H, Laakso M, Uusitupa M. 1998. Arteriosclerosis, thrombosis, and vascular biology. 18: 1606-1610

Randomised placebo-controlled trial of orlistat for weight loss and prevention of weight regain in obese patients

Sjöström L, Rissanen A, Andersen T, Boldrin M, Golay A, Koppeschaar HPF, Krempf M, for the European Multicentre Orlistat Group, Uusitupa M. 1998. The Lancet. 352: 167-173

Risk factors of cardiovascular disease in the elderly

Uusitupa MIJ, Sarkkinen ES. 1998. Nutrition metabolism and cardiovascular diseases. 8: 341-348

Saliva in non-insulin-dependent diabetic patients and control subjects: the role of the autonomic nervous system

Meurman JH, Collin H-L, Niskanen L, Töyry J, Alakuijala P, Keinänen S, Uusitupa M. 1998. Oral surgery oral medicine oral pathology oral radiology and endodontology. 86: 69-76

Sepelvaltimotaudin sekundaariprevention toteutuminen KYS:ssa hoidetuilla potilailla: EUROASPIRE-tutkimuksen tuloksia

Koukkunen H, Kemppainen A, Lehto S, Erkkilä A, Sarkkinen E, Uusitupa M, Pyörälä K. 1998. Lääkärilehti. 53: 2029-2041

Serum leptin, food intake and preferences for sugar and fat in obese women

Karhunen LJ, Lappalainen RI, Haffner SM, Valve RH, Tuorila H, Miettinen H, Uusitupa MIJ. 1998. International journal of obesity. 1998: 819-821

Synergistic effect of polymorphisms in uncoupling protein 1 and beta3-adrenergic receptor genes on basal metabolic rate in obese Finns

Valve R, Heikkinen S, Rissanen A, Laakso M, Uusitupa M. 1998. Diabetologia. 41: 357-361

The effect of a very low-calorie diet-induced weight loss on the severity of obstructive sleep apnoea and autonomic nervous function in obese patients with obstructive sleep apnoea syndrome

Kansanen M, Vanninen E, Tuunainen A, Pesonen P, Tuononen V, Hartikainen J, Mussalo H, Uusitupa M. 1998. Clinical physiology and functional imaging. 18: 377-385

The effect of quality and amount of dietary fat on the susceptibility of low density lipoprotein to oxidation in subjects with impaired glucose tolerance

Schwab US, Sarkkinen ES, Lichtenstein AH, Li Z, Ordovas JM, Schaefer EJ, Uusitupa MIJ. 1998. European journal of clinical nutrition. 52: 452-458

Abnormal myocardial kinetics of 123I-heptadecanoic acid in subjects with impaired glucose tolerance

Turpeinen AK, Kuikka JT, Vanninen E, Uusitupa MIJ. 1997. Diabetologia. 40: 541-549

Altered antioxidant enzyme defences in insulin-dependent diabetic men with increased resting and exercise-induced oxidative stress

Atalay M, Laaksonen DE, Niskanen L, Uusitupa M, Hänninen O, Sen CK. 1997. Acta physiologica. 161: 195-201

Changes in autonomic nervous function during the 4-year follow-up in middle-aged diabetic and nondiabetic subjects initially free of coronary heart disease

Mustonen J, Uusitupa M, Mäntysaari M, Länsimies E, Pyörälä K, Laakso M. 1997. Journal of internal medicine. 241: 227-235

Determinants of resting energy expenditure in obese non-diabetic caucasian women

Karhunen L, Franssila-Kallunki A, Rissanen A, Kervinen K, Kesäniemi YA, Uusitupa M. 1997. International journal of obesity. 21: 197-202

Diabetesnefropati - screening, uppföljning och behandling

Koivisto V, Groop PH, Huttunen N-P, Kivekäs J, Pasternack A, Uusitupa M, Viikari J. 1997. NORDISK MEDICIN. 112: 154-162

Divergent association of apolipoprotein E polymorphism with vascular disease in patients with NIDDM and control subjects

Vauhkonen I, Niskanen L, Ryynänen M, Voutilainen R, Partanen J, Töyry J, Mercuri M, Rauramaa R, Uusitupa M. 1997. Diabetic medicine. 14: 748-756

Divergent development of autonomic and peripheral somatic neuropathies in NIDDM

Töyry JP, Partanen JVS, Niskanen LK, Länsimies EA, Uusitupa MIJ. 1997. Diabetologia. 40: 953-958

Do high proinsulin and C-peptide levels play a role in autonomic nervous dysfunction? Power spectral analysis in patients with non-insulin-dependent diabetes and nondiabetic subjects

Töyry JP, Niskanen LK, Mäntysaari MJ, Länsimies EA, Haffner SM, Miettinen HJJ, Uusitupa MIJ. 1997. Circulation. 96: 1185-1191

Effects of dietary fat modification on fibrinogen, factor VII, and plasminogen activator inhibitor-1 activity in subjects with impaired glucose tolerance

Niskanen L, Schwab US, Sarkkinen ES, Krusius T, Vahtera E, Uusitupa MIJ. 1997. Metabolism: clinical and experimental. 46: 666-672

Incorporation of n-3 fatty acids into plasma lipid fractions, and erythrocyte membranes and platelets during dietary supplementation with fish, fish oil, and docosahexaenoic acid-rich oil among healthy young men

Vidgren HM, Ågren JJ, Schwab U, Rissanen T, Hänninen O, Uusitupa MIJ. 1997. Lipids. 32: 697-705

Kaura ja keliakia

Janatuinen E, Julkunen R, Uusitupa M. 1997. Duodecim

Keliakian hoitosuositus

Suomen Gastroenterologiayhdistys Ry, Uusitupa M, Julkunen R. 1997. Duodecim. 113: [6]

Lathosterol and other non-cholesterol sterols during treatment of hypercholesteroleamia with beta-glucan-rich oat bran

Uusitupa MIJ, Miettinen TA, Sarkkinen ES, Ruuskanen E, Kervinen K, Kesäniemi YA. 1997. European journal of clinical nutrition. 51: 607-611

Lihavan potilaan tutkiminen ja hoitomuodon valinta

Mustajoki P, Rissanen A, Uusitupa M. Teoksessa: Fogelholm M, Mustajoki P, Rissanen A, Uusitupa M(toim.) , 1997. Lihavuus. Ongelma ja hoito. s. 88-92. Duodecim

Lihavuuden syyt

Rissanen A, Uusitupa M. Teoksessa: Fogelholm M, Mustajoki P, Rissanen A, Uusitupa M(toim.) , 1997. Lihavuus. Ongelma ja hoito. s. 56-67. Duodecim

Lihavuus ja terveys

Uusitupa M. Teoksessa: Fogelholm M, Mustajoki P, Rissanen A, Uusitupa M(toim.) , 1997. Lihavuus.Ongelma ja hoito. s. 15-25. Duodecim

Mahapantaleikkaus - sairaalloisen lihavuuden uusi hoitomuoto

Pirinen E, Uusitupa M, Tuononen V, Poikolainen E, Pääkkönen M, Alhava E. 1997. Duodecim. 113: 1471-1475

Metabolic effects of diets rich in saturated and omega-6 polyunsatured fatty acids in healthy young females

Schwab US, Karhapää P, Sarkkinen ES, Salminen I, Laakso M, Uusitupa MIJ. 1997. DIABETES, NUTRITION & METABOLISM. 10: 35-38

Miten aikuisiän diabeteksen hoitotuloksia voitaisiin parantaa

Uusitupa M. 1997. Lääkärilehti

Palmitic and stearic acid enriched diets have similar effects on glucose metabolism in healthy young females

Schwab US, Niskanen L, Uusitupa MIJ. 1997. Nutrition metabolism and cardiovascular diseases. 7: 315-319

Polymorphism of the Beta3-adrenergic receptor gene affects basal metabolic rate in obese Finns

Sipiläinen R, Uusitupa M, Heikkinen S, Rissanen A, Laakso M. 1997. Diabetes. 46: 77-80

Ravinto,terveytemme perusta nyt ja tulevaisuudessa

Uusitupa M, Aro A, Mykkänen H, Rissanen A. 1997. Lääkärilehti. 52: 2181-2186

Regional cerebral blood flow during food exposure in obese and normal-weight womem

Karhunen LJ, Lappalainen RI, Vanninen EJ, Kuikka JT, Uusitupa MIJ. 1997. Brain. 120: 1675-1684

Relationship of metabolic variables to abdominal adiposity measured by different anthropometric measurements and dual-energy X-ray absorptiometry in obese middle-aged women

Rissanen P, Hämäläinen P, Vanninen E, Tenhunen-Eskelinen M, Uusitupa M. 1997. International journal of obesity. 21: 367-371

Satellite Symposium on Nutrition, Obesity and Diabetes

Uusitupa M. 1997. Kuopio University Publications D. Medical Sciences. . -

Serum leptin and short-term regulation of eating in obese women

Karhunen L, Haffner S, Lappalainen R, Turpeinen A, Miettinen H, Uusitupa M. 1997. Clinical science. 92: 573-578

Serum leptin in obesity is related to gender and body fat topography but does not predict successful weight loss

Niskanen LK, Haffner S, Karhunen LJ, Turpeinen AK, Miettinen H, Uusitupa MIJ. 1997. European journal of endocrinology. 137: 61-67

Serum leptin in relation to resting energy expenditure and fuel metabolism in obese subjects

Niskanen L, Haffner S, Karhunen LJ, Turpeinen AK, Miettinen H, Uusitupa MIJ. 1997. International journal of obesity. 21: 309-313

Serum leptin in subjects with impaired glucose tolerance in relation to insulin sensitivity and first-phase insulin responce

Turpeinen AK, Haffner SM, Louheranta AM, Niskanen LK, Miettinen H, Uusitupa MIJ. 1997. International journal of obesity. 21: 284-287

Subjective and physiological cephalic phase responses to food in obese binge-eating women

Karhunen LJ, Lappalainen RI, Tammela L, Turpeinen AK, Uusitupa MIJ. 1997. International journal of eating disorders. 21: 321-328

Threonine allele in codon 54 of the fatty acid binding protein 2 gene does not modify the fatty acid composition of serum lipids in obese subjects

Vidgren HM, Sipiläinen RH, Heikkinen S, Laakso M, Uusitupa MIJ. 1997. European journal of clinical investigation. 27: 405-408

Variants in the human intestinal fatty acid binding protein 2 gene in obese subjects

Sipiläinen R, Uusitupa M, Heikkinen S, Rissanen A, Laakso M. 1997. Journal of clinical endocrinology and metabolism. 82: 2629-2632

Aikuistyypin diabeteksen ehkäisylle on vankat perusteet

Uusitupa M. 1996. DIABETES (LÄÄKÄRILIITE, HELMIKUU)

Aikuistyypin diabeteksen hoidon periaatteet - repetitio mater studiorum est

Uusitupa M. 1996. Lääkärilehti. 51: 1065-1067

Apolipoprotein E phenotype modifies metabolic and hemodynamic abnormalities related to central obesity in women 1-3

Uusitupa MIJ, Karhunen L, Rissanen A, Franssila-Kallunki A, Niskanen L, Kervinen K, Kesäniemi YA. 1996. American journal of clinical nutrition. 64: 131-136

Apolipoprotein E phenotypes and response to dietary fat and cholesterol

Kesäniemi YA, Savolainen MJ, Uusitupa M, Sarkkinen E, Rantala M, Kervinen K. Teoksessa: Bray GA, Ryan DH(toim.) , 1996. Nutrition, Genetics, and Heart Disease. s. 379-387. Louisiana State University Press

Athletic heart: a metabolic, anatomical, and functional study

Turpeinen AK, Kuikka JT, Vanninen E, Vainio P, Vanninen R, Litmanen H, Koivisto VA, Bergström K, Uusitupa MIJ. 1996. Medicine and science in sports and exercise. 28: 33-40

Autoantibodies against oxidized LDL do not predict atherosclerotic vascular disease in non-insulin-dependent diabetes mellitus

Uusitupa MIJ, Niskanen L, Luoma J, Vilja P, Mercuri M, Rauramaa R, Ylä-Herttuala S. 1996. Arteriosclerosis, thrombosis, and vascular biology. 16: 1236-1242

Autonomic neuropathy predicts the development of stroke in patients with non-insulin-dependent diabetes mellitus

Töyry JP, Niskanen LK, Länsimies EA, Partanen KPL, Uusitupa MIJ. 1996. Stroke. 27: 1316-1318

Body-size indicators and risk of breast cancer according to menopause and estrogen-reseptor status

Männistö S, Pietinen P, Pyy M, Palmgren J, Eskelinen M, Uusitupa M. 1996. International journal of cancer. 68: 8-13

Carotid artery intima-media thickness in elderly patients with NIDDM and in nondiabetic subjects

Niskanen L, Rauramaa R, Miettinen H, Haffner SM, Mercuri M, Uusitupa M. 1996. Stroke. 27: 1986-1992

Demonstration of regional sympathetic denervation of the heart in diabetes

Turpeinen AK, Vanninen E, Kuikka JT, Uusitupa MIJ. 1996. Diabetes care. 19: 1083-1090

Determinants of the cephalic-phase insulin response in obese nondiabetic subjects

Karhunen LJ, Lappalainen RI, Niskanen LK, Turpeinen AK, Uusitupa MIJ. 1996. Metabolism: clinical and experimental. 45: 168-173

Diabeettinen nefropatia-seulonta, seuranta ja hoito 1996

Suomen Diabetesliiton nefropatiatyöryhmä, Uusitupa M. 1996. Lääkärilehti. 51: 2479-2489

Diabetestutkimuksen näkymiä

Uusitupa M. 1996. DIABETES (LÄÄKÄRILIITE, JOULUKUU). 48: 3-5

Different effects of palmitic and stearic acid-enriched diets on serum lipids and lipoproteins and plasma cholesterol ester transfer protein activity in healthy young women

Schwab US, Maliranta HM, Sarkkinen ES, Savolainen MJ, Kesäniemi YA, Uusitupa MIJ. 1996. Metabolism: clinical and experimental. 45: 143-149

Does lactose intolerance predispose to low bone density? A population-based study of perimenopausal Finnish women

Honkanen R, Pulkkinen P, Järvinen R, Kröger H, Lindstedt K, Tuppurainen M, Uusitupa M. 1996. Bone. 19: 23-28

Early lifestyle intervention in patients with non-insulin-dependent diabetes mellitus and impaired glucose tolerance

Uusitupa MIJ. 1996. Annals of medicine. 28: 445-449

Effects of moderate salt restriction alone and in combination with cilazapril on office and ambulatory blood pressure

Uusitupa M, Korhonen M, Litmanen H, Niskanen L, Väisänen S, Rauramaa R. 1996. Journal of human hypertension. 10: 319-326

Hemodialyysipotilaiden ravitsemustila

Alakärppä S, Nuutinen O, Lampainen E, Uusitupa M. 1996. Duodecim. 112: 986-993

Increased resting and excercise-indused oxidative stress in young IDDM men

Laaksonen DE, Atalay M, Niskanen L, Uusitupa M, Hänninen O, Sen CK. 1996. Diabetes care. 19: 569-574

Lääkkeettömät keinot aikuistyypin diabeteksen ehkäisyssä

Uusitupa M. 1996. DIABETES (LÄÄKÄRILIITE, HELMIKUU). 48: 13-16

Measurement of myocardial accumulation of 123I-metaiodobenzylguanidine for studying cardiac autonomic neuropathy in diabetes mellitus

Mäntysaari M, Kuikka J, Mustonen J, Tahvanainen K, Vanninen E, Länsimies E, Uusitupa M. 1996. Clinical autonomic research. 6: 163-169

Metabolic control and macrovascular disease

Uusitupa M. Teoksessa: Alberti P,Zimmet RA,DeFronzo, Keen H(toim.) , 1996. International Textbook of Diabetes Mellitus, Second Edition. s. 1-17. K.G.M.M

Onko kalarasvalla ja n-3-sarjan monityydyttymättömillä rasvahapoilla merkitystä sairauksien ehkäisyssä ja hoidossa?

Sarkkinen E, Uusitupa M. 1996. Duodecim. 112: 1755-1763

Ravitsemusneuvonnasta lisäpotkua diabeetikon hoitoon

Uusitupa M. 1996. DIABETES (LÄÄKÄRILIITE, HUHTIKUU)

Sepelvaltimotaudin ehkäisy käytännön lääkärintyössä

Suomen Sisätautilääkärien yhdistyksen, Suomen Kardiologisen seuran, Suomen Verenpaineyhdistyksen, Kunnallislääkärit-yhdistyksen, Suomen Teollisuuslääketieteen yhdistyksen ja Suomen Sydäntautiliiton työryhmä, Pyörälä K, Uusitupa M. 1996. Lääkärilehti. 51: 783-802

The authors reply (to Oats in celiac disease)

Janatuinen EK, Julkunen RJK, Uusitupa MI. 1996. The new england journal of medicine

The effects of monounsaturated-fat enriched diet and polyunsaturated-fat enriched diet on lipid and glucose metabolism in subjects with impaired glucose tolerance

Sarkkinen E, Schwab U, Niskanen L, Hannuksela M, Savolainen M, Kervinen K, Kesäniemi A, Uusitupa MIJ. 1996. European journal of clinical nutrition. 50: 592-598

The effects of weight loss on insulin sensitivity, skeletal muscle composition and capillary density in obese non-diabetic subjects

Niskanen L, Uusitupa M, Sarlund H, Siitonen O, Paljärvi L, Laakso M. 1996. International journal of obesity. 20: 154-160

The nutritional status of Finnish home-living elderly people and the relationship between energy intake and chronic diseases

Rissanen PM, Laakkonen EI, Suntioinen S, Penttilä IM, Uusitupa MI. 1996. Age and ageing. 25: 133-138

Troglitazone, an insulin action enhancer, improves metabolic control in NIDDM patients

Kumar S, Boulton AJM, Beck-Nielsen H, Berthezene F, Muggeo M, Persson B, Spinas GA, Donoghue S, Lettis S, Stewart-Long P, for the Troglitazone study group, Uusitupa M. 1996. Diabetologia. 39: 701-709

Ventricular repolarization is correlated with metabolic control in newly diagnosed type 2 diabetes

Vanninen E, Uusitupa MIJ, Länsimies E. 1996. Clinical physiology and functional imaging. 16: 449-461

Vitamin E concentration in breast adipose tissue of breast cancer patients (Kuopio, Finland)

Zhu Z, Parviainen M, Männistö S, Pietinen P, Eskelinen M, Syrjänen K, Uusitupa M. 1996. Cancer causes and control. 7: 591-595

A comparison of diets with and without oats in adults with celiac disease

Janatuinen EK, Pikkarainen PH, Kemppainen TA, Kosma V-M, Järvinen RMK, Uusitupa MIJ, Julkunen RJK. 1995. The new england journal of medicine. 333: 1033-1037

Aikuistyypin diabeteksen hoitosuositus uusittu

Uusitupa M. 1995. Lääkärilehti

Dietary intake and nutritional status of athletic and nonathletic children in early puberty

Rankinen T, Fogelholm M, Kujala U, Rauramaa R, Uusitupa M. 1995. International journal of sport nutrition and exercise metabolism. 5: 136-150

Energiestoffwechsel bei typ-II-(non-insulindependent) Diabetes mellitus und Adipositas

Uusitupa M. 1995. DIABETES UND STOFFWECHSEL. 4: 263-264

Fatty acid composition of breast adipose tissue in breast cancer patients and in patients with bening breast disease

Zhu ZR, Ågren J, Männistö S, Pietinen P, Eskelinen M, Syrjänen K, Uusitupa M. 1995. Nutrition and cancer: an international journal. 24: 151-160

GAD antibodies in NIDDM. Ten-year follow-up from the diagnosis

Niskanen LK, Tuomi TM, Karjalainen J, Groop LC, Uusitupa MIJ. 1995. Diabetes care. 18: 1557-1565

Hyperglycemia and cardiovascular risk in NIDDM

Uusitupa MIJ, Niskanen LK. 1995. Diabetes care

Hyperkolesterolemian hoito lääkäreiden ilmoituksen mukaan vuosina 1985 ja 1992

Nissinen A, Enlund H, Korhonen M, Uusitupa M, Niskanen L, Lempiäinen-Kuosa P, Tuomilehto J. 1995. Lääkärilehti. 50: 2003-2006

Intakes of nutrients and nutritional status in coeliac patients

Kemppainen T, Uusitupa M, Janatuinen E, Järvinen R, Julkunen R, Pikkarainen P. 1995. Scandinavian journal of gastroenterology. 30: 575-579

Kauraa keliaakikoille

Uusitupa M. 1995. Lääkärilehti. 50: 3476-3477

Lauric and palmitic acid-enriched diets have minimal impact on serum lipid and lipoprotein concentrations and glucose metabolism in healthy young women

Schwab US, Niskanen LK, Maliranta HM, Savolainen MJ, Kesäniemi YA, Uusitupa MIJ. 1995. Journal of nutrition. 125: 466-473

Liikunta, energiankulutus ja ravitsemus

Fogelholm M, Uusitupa M. Teoksessa: Vuori I, Taimela S(toim.) , 1995. Liikuntalääketiede. s. 69-79. Duodecim

Mental well-being in people with non-insulin-dependent diabetes

Viinamäki H, Niskanen L, Uusitupa M. 1995. Acta psychiatrica scandinavica. 92: 392-397

Metabolinen oireyhtymä

Uusitupa M. 1995. KÄYTÄNNÖN LÄÄKÄRI. 4: 147-151

Miten ehkäistä diabeetikon koronaaritautia?

Uusitupa M. 1995. DIABETES JA LÄÄKÄRI. : 7,11

Mitä rasvaa leivän päälle?

Uusitupa M, Sarkkinen E. 1995. Duodecim

Myocardial sympathetic nervous dysfunction detected with iodine-123-MIBG is associated with low heart rate variability after myocardial infarction

Mäntysaari M, Kuikka J, Hartikainen J, Mustonen J, Mussalo H, Tahvanainen K, Länsimies E, Uusitupa M, Pyörälä K. 1995. Journal of nuclear medicine. 36: 956-961

Natural history of peripheral neuropathy in patients with non-insulin-dependent diabetes mellitus

Partanen J, Niskanen L, Lehtinen J, Mervaala E, Siitonen O, Uusitupa M. 1995. The new england journal of medicine. 333: 89-94

Plasma lipid peroxidation and hyperglycaemia: a connection trough hyperinsulinaemia?

Niskanen LK, Salonen JT, Nyyssönen K, Uusitupa MIJ. 1995. Diabetic medicine. 12: 802-808

Ravitsemustilan arviointi käytännön potilastyössä

Uusitupa M, Nuutinen L. 1995. Lääkärilehti. 50: 888-889

Recommendations for the nutritional management of patients with diabetes mellitus

Slama G, Lean M, Mann J, Toeller M, Chantelau E, Van Gaal L, Heine R, Karamantos B, Karlstrom B, De Leeuw I, Librenti M, Riccardi G, Rivellese A, Teuscher A, Uusitupa M, Vessby B. 1995. DIABETES, NUTRITION & METABOLISM. 8: 1-4

Short-term and long-term memory in elderly patients with NIDDM

Helkala E-L, Niskanen L, Viinamäki H, Partanen J, Uusitupa M. 1995. Diabetes care. 18: 681-685

Tehostettu ravitsemushoito

Nuutinen L, Uusitupa M. 1995. Lääkärilehti. 50: 1991-1993

The role of rye in Finnish diet

Mykkänen H, Sipiläinen R, Uusitupa M. Teoksessa: Poutanen K, Autio K(toim.) , 1995. International Rye Symposium: Technology and Products, VTT Symposium 161. s. 77-82. Technical Research Centre of Finland

Uniapneapotilaiden laihdutus ja autonomisen hermoston toiminta

Pesonen PHM, Vanninen E, Tuononen V, Tuunainen A, Kansanen M, Hartikainen J, Mussalo H, Uusitupa M. 1995. Duodecim. 111: 1136-1140

Vitamin A concentration in breast adipose tissue of breast cancer patients

Zhu ZR, Parviainen M, Männistö S, Pietinen P, Eskelinen M, Syrjänen K, Uusitupa M. 1995. Anticancer research. 15: 1593-1596

Aikuistyypin diabetes: Hyperglykemia ja elinkomplikaatiot

Uusitupa M. 1994. DIABETES (LÄÄKÄRILIITE, HELMIKUU). 2: 10-17

Apolipoprotein E phenotype and blood pressure

Uusitupa M, Sarkkinen E, Kervinen K, Kesäniemi YA. 1994. The Lancet. 343: 57

Apoprotein (a) is not a predictor of cardiovascular events in elderly patients with Type 2 (non-insulin-dependent) diabetes

Niskanen L, Mykkänen L, Uusitupa M, Karonen S-L. 1994. CARDIOVASCULAR RISK FACTORS. 4: 71-73

Cholesterol synthesis in humans

Uusitupa M. Teoksessa: Lairon D(toim.) , 1994. Mechanisms of action of dietary fibre on lipid and cholesterol metabolism. Proceedings of a Workshop Held. s. 71-75. Commission of the European Communities

Do genetic markers modify serum cholesterol lowering effects of dietary fiber?

Uusitupa M. Teoksessa: Lairon D(toim.) , 1994. Mechanisms of action of dietary fibre on lipid and cholesterol metabolism. Proceedings of a Workshop Held. s. 159-161. Commission of the European Communities

Effects of two high-fat diets with different fatty acid compositions on glucose and lipid metabolism in healthy young women

Uusitupa M, Schwab U, Mäkimattila S, Karhapää P, Sarkkinen E, Maliranta H, Ågren J, Penttilä I. 1994. American journal of clinical nutrition. 59: 1310-1316

Enteraalinen vai parenteraalinen ravitsemus?

Nuutinen L, Uusitupa M. 1994. Duodecim. 110: 1935-1943

Fatty acid composition of serum cholesterol esters, and erythrocyte and platelet membranes as indicators of long-term adherence to fat-modified diets

Sarkkinen ES, Ågren JJ, Ahola I, Ovaskainen M-L, Uusitupa MIJ. 1994. American journal of clinical nutrition. 59: 364-70

Fructose in the diabetic diet

Uusitupa MIJ. 1994. American journal of clinical nutrition. 59: 753S-757S

Long-term effects of four fat-modified diets on blood pressure

Uusitupa MIJ, Sarkkinen ES, Torpström J, Pietinen P, Aro A. 1994. Journal of human hypertension. 8: 209-218

Long-term effects of three fat-modified diets in hypercholesterolemic subject

Sarkkinen ES, Uusitupa MIJ, Pietinen P, Aro A, Ahola I, Penttilä I, Kervinen K, Kesäniemi YA. 1994. Atherosclerosis. 105: 9-23

Metabolic and dietary variables associated with glycaemic control in patients with recently diagnosed Type II diabetes mellitus

Laitinen J, Uusitupa M, Ahola I, Laakso M, Siitonen O. 1994. DIABETES, NUTRITION & METABOLISM. 7: 77-87

Metabolic and dietery determinants of serum lipids in obese patients with recently diagnosed non-insulin-dependent diabetes

Laitinen J, Uusitupa M, Ahola I, Siitonen O. 1994. Annals of medicine. 26: 119-124

Metabolic evolution of type 2 diabetes: a 10-year follow-up from the time of diagnosis

Niskanen L, Karjalainen J, Siitonen O, Uusitupa M. 1994. Journal of internal medicine. 236: 263-270

Relation of habitual diet and cardiorespiratory fitness to blood coagulation and fibrinolytic factors

Rankinen T, Rauramaa R, Väisänen S, Penttilä IM, Uusitupa M. 1994. Thrombosis and haemostasis. 71: 180-183

Screening for mutations in the exon 26 of the apolipoprotein B gene in hypercholesterolemic Finnish families by the single-strand conformation polymorphism method

Ilmonen M, Heliö T, Ebeling T, Pyörälä K, Uusitupa M, Palotie A, Tikkanen MJ. 1994. Human mutation. 4: 217-223

Stability and magnitude of serum low-density lipoprotein response to a 6-month dietary intervention

Sarkkinen ES, Uusitupa M. 1994. Nutrition metabolism and cardiovascular diseases. 4: 36-42

Tehostettu ruokavalio-ohjaus voi motivoida parempaan hoitotulokseen

Uusitupa M. 1994. DIABETES (LÄÄKÄRILIITE, SYYSKUU). 46: 17-25

Therapeutic traditions in type 2 diabetes - are they changing?

Niskanen L, Enlund H, Jormanainen V, Nissinen A, Uusitupa M. 1994. European journal of clinical pharmacology. 46: 101-105

Veren suurentunut glukoosipitoisuus lisää aikuistyypin diabeetikon valtimotautiriskiä

Uusitupa M, Niskanen L. 1994. Duodecim

Cardiac arrhythmias in the differential diagnosis of epilepsy

Nousiainen U, Mervaala E, Ylinen A, Uusitupa M, Riekkinen P. 1989. Journal of neurology. 236: 93-96

Association of omega 3 polyunsaturated fatty acids with incident chronic kidney disease: pooled analysis of 19 cohorts

Combination of Multiple Low-Risk Lifestyle Behaviors and Incident Type 2 Diabetes: A Systematic Review and Dose-Response Meta-analysis of Prospective Cohort Studies

Diabeteksen kansallisen ehkäisyhankkeen pitkäaikaiset vaikutukset ja merkitys

Eating behavior dimensions and 9-year weight loss maintenance: a sub-study of the Finnish Diabetes prevention study

Evidence-based European recommendations for the dietary management of diabetes

Genome-wide association study and functional characterization identifies candidate genes for insulin-stimulated glucose uptake

Lifestyle Intervention Guided by Group and Internet-Based Counseling in the T2D-GENE Trial Supports Its Applicability and Feasibility

Not all very-low-carbohydrate diets are created equal. Reply to Conte C, Camajani E, Lai A, Caprio M [letter]

The effect of vitamin D3 supplementation on atrial fibrillation in generally healthy men and women: the Finnish Vitamin D Trial

Towards Individually Tailored Diets in Prevention and Treatment of Diabetes?

Type 2 Diabetes Prevention Programs — From Proof-of-Concept Trials to National Intervention and Beyond

Analysis of the SYSDIET Healthy Nordic Diet randomized trial based on metabolic profiling reveal beneficial effects on glucose metabolism and blood lipids

Genetic Predictors of Change in Waist Circumference and Waist-to-Hip Ratio With Lifestyle Intervention: The Trans-NIH Consortium for Genetics of Weight Loss Response to Lifestyle Intervention

Indolepropionic Acid, a Gut Bacteria-Produced Tryptophan Metabolite and the Risk of Type 2 Diabetes and Non-Alcoholic Fatty Liver Disease

Longitudinal Branched-Chain Amino Acids, Lifestyle Intervention, and Type 2 Diabetes in the Finnish Diabetes Prevention Study

Nordic dietary patterns and cardiometabolic outcomes: a systematic review and meta-analysis of prospective cohort studies and randomised controlled trials

PUFA ω-3 and ω-6 biomarkers and sleep: a pooled analysis of cohort studies on behalf of the Fatty Acids and Outcomes Research Consortium (FORCE)

Sources of animal proteins and type 2 diabetes risk – decreasing the consumption of red meat is well grounded

Vitamin D supplementation and prevention of cardiovascular disease and cancer in the Finnish Vitamin D Trial: a randomized controlled trial

Diabetes sairautena ja sen ravitsemus- ja muu hoito

Fruit and Vegetables consumption and Type 2 diabetes prevention

Heikentynyt glukoosinsieto, insuliiniresistenssi ja metabolinen oireyhtymä ja niiden ehkäisy

Kehon koostumuksen mittaaminen

Kihti ja nivelreuma

Lihavuuden ehkäisy

Lihavuuden hoito

Lihavuuden syyt

Lihavuus sairautena

Long-term outcomes of lifestyle intervention to prevent type 2 diabetes in people at high risk in primary health care

Mitä suomalainen tyypin 2 diabeteksen ehkäisytutkimus DPS on opettanut?

Ravitsemustiede

Ravitsemustilan arviointi ja ravinnonsaannin tehostaminen

Serum Levels of Plasmalogens and Fatty Acid Metabolites Associate with Retinal Microangiopathy in Participants from the Finnish Diabetes Prevention Study

Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability

Sydämen vajaatoiminta

Sydän- ja verisuonitautien ehkäisy ja riskitekijöiden lääkkeetön hoito

Syömisen säätely

Tehohoitopotilaan ravitsemushoito

The trans-ancestral genomic architecture of glycemic traits

Tyypin 2 diabeteksen Käypä hoito -suosituksessa laihduttaminen jää sivuosaan

Tyypin 2 diabeteksen ehkäisy

Uudet tutkimusmenetelmät ja yksilöity ravitsemushoito

Covid-19-tauti muistuttaa lihavuuden hoidon merkityksestä

Divergent pathologies and treatment options for diabetic neuropathies

Evolving Nutritional Therapy for Diabetes Mellitus

Fatty acids in the de novo lipogenesis pathway and incidence of type 2 diabetes: A pooled analysis of prospective cohort studies

Metformin and risk of Alzheimer's disease among community-dwelling people with diabetes: a national case-control study

The Effects of Different Quantities and Qualities of Protein Intake in People With Diabetes Mellitus

Tyypin 2 diabetesepidemia odottaa edelleen ratkaisuja

An Isocaloric Nordic Diet Modulates RELA and TNFRSF1A Gene Expression in Peripheral Blood Mononuclear Cells in Individuals with Metabolic Syndrome-A SYSDIET Sub-Study

Associations of circulating very-long-chain saturated fatty acids and incident type 2 diabetes: a pooled analysis of prospective cohort studies

Biomarkers of Dietary Omega-6 Fatty Acids and Incident Cardiovascular Disease and Mortality: An Individual-Level Pooled Analysis of 30 Cohort Studies

Good news from the Da Qing Diabetes Prevention Outcome Study-healthy lifestyles result in long-term cardiovascular benefits

Healthy Nordic Diet Modulates the Expression of Genes Related to Mitochondrial Function and Immune Response in Peripheral Blood Mononuclear Cells from Subjects with the Metabolic Syndrome - A SYSDIET Sub-Study

Kalaöljyt ja sydäntautien ehkäisy

Life Style Intervention Improves Retinopathy Status - The Finnish Diabetes Prevention Study

Nordic Diet and Inflammation - A Review of Observational and Intervention Studies

Prevention of Type 2 Diabetes by Lifestyle Changes: A Systematic Review and Meta-Analysis

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

Quantitative assessment of betainized compounds and associations with dietary and metabolic biomarkers in the randomized study of the healthy Nordic diet (SYSDIET)

Associations of serum indolepropionic acid, a gut microbiota metabolite, with type 2 diabetes and low-grade inflammation in high-risk individuals

Diets rich in whole grains increase betainized compounds associated with glucose metabolism

Early fecal microbiota composition in children who later develop celiac disease and associated autoimmunity

Fatty acid biomarkers of dairy fat consumption and incidence of type 2 diabetes: A pooled analysis of prospective cohort studies

Genes and Dietary Fatty Acids in Regulation of Fatty Acid Composition of Plasma and Erythrocyte Membrane

Keinotekoiset makeutteet

Prevention of type 2 diabetes - success story that is waiting for next steps

Remission of type 2 diabetes : mission not impossible

Serum Adiponectin/Ferritin Ratio in Relation to the Risk of Type 2 diabetes and Insulin Sensitivity

Susceptibility of low-density lipoprotein particles to aggregate depends on particle lipidome, is modifiable, and associates with future cardiovascular deaths

Varhainen laihdutus voi kääntää tyypin 2 diabeteksen remissioon

A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk

Alterations in fatty acid metabolism in response to obesity surgery combined with dietary counseling

Fasting serum hippuric acid is elevated after bilberry (Vaccinium myrtillus) consumption and associates with improvement of fasting glucose levels and insulin secretion in persons at high risk of developing type 2 diabetes

Indolepropionic acid and novel lipid metabolites are associated with a lower risk of type 2 diabetes in the Finnish Diabetes Prevention Study

Instability of LDL particles predicts future cardiovascular deaths

Painopiste preventioon!

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Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity